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  Messages 1-15 from 15 matching the search criteria.
Study: Single Dose Of CBD Shown To Reduce Blood Pressure Darrell Miller 8/25/17
What Makes Curamed such a good Pain Remedy? Darrell Miller 10/24/11
Buckthorn Of The Sea Darrell Miller 8/5/09
Capsicum - Cayenne Red Pepper Darrell Miller 7/28/08
Benefits - Supports joint function and tissue health* Darrell Miller 12/11/06
Curcumin - Turmeric Extract Darrell Miller 8/19/05
WHAT EXACTLY IS PYCNOGENOL? Darrell Miller 7/13/05
MILK THISTLE: A VITAL COMPONENT OF LIVER REHABILITATION Darrell Miller 7/12/05
HISTORY Darrell Miller 7/12/05
HISTORY Darrell Miller 6/25/05
HISTORY Darrell Miller 6/23/05
GPC (GlyceroPhosphoCholine) Versatile Life Support Nutrient .... Darrell Miller 6/21/05
Winter Survival Kit Darrell Miller 6/13/05
Resveratrol - New Hope for Long Life ... Darrell Miller 6/6/05
Menopause Multiple - Eternal Woman Darrell Miller 6/3/05




Study: Single Dose Of CBD Shown To Reduce Blood Pressure
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Date: August 25, 2017 09:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Study: Single Dose Of CBD Shown To Reduce Blood Pressure





A recent study conducted at the University of Nottingham in England has shown that a single dose of Cannabidiol can effectively lower blood pressure for individuals that are suffering from high blood pressure. This is great news, considering Cannabidiol is a non-addictive, natural medication. It is also an amazing breakthrough because this means that it can treat many other cardiovascular disorders, not just hypertension. Cannabidiol is believed to be a neuroprotectant that can help prevent cardiovascular disease and stroke, in addition to lowering an elevated heart rate.

Key Takeaways:

  • CBD may help prevent cardiovascular disease, specifically by lowering systolic blood pressure.
  • Patients who received one oral dose had an average of 5-7 mmHg drop in systolic blood pressure.
  • CBD may help reduce cardiovascular risk in other ways- like being a vasodilator and protecting neurons that regulate heartbeat.

"Nearly 75 million adults in the United States suffer from hypertension, or high blood pressure. That means around 32 percent of the population is at an increased risk for heart disease and stroke. It’s very promising that CBD has the possibility of reducing and preventing certain cardiovascular disorders."

Read more: http://www.cannatech.news/2017/08/21/single-dose-cbd-shown-reduce-blood-pressure/

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What Makes Curamed such a good Pain Remedy?
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Date: October 24, 2011 08:24 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Makes Curamed such a good Pain Remedy?

Curamed And Pain (Inflammation)

Curamed is an herbal supplement primarily used as a pain relief treatment. This product is a combination of many herbs which has anti - inflammatory properties. In addition, this supplement which is a blend of many herbs is also useful in enhancing the defense mechanism of the body against harmful microorganisms and illnesses. And not to mention, Curamed also contains powerful antioxidants to help protect the body from free radical damage.

Many users have reported that Curamed is effective as a pain remedy. Clinically, Curamed is approximately equal to 4,000 milligrams of curcumin and 85,000 milligrams of turmeric. Turmeric is a pepper - like herb which has a bitter taste but mild aroma. This herb is commonly used since the ancient times as a home remedy for pain. The mechanism of action of this herb is said to be because of its ability to reduce inflammation thus reducing swelling and pain sensation. Clinical studies showed that the substance in turmeric is called curcumin. This is the chemical substance in the herb which has a strong anti – inflammatory property. It can even relieve swelling and pain during osteoarthritis and rheumatoid arthritis attacks. The anti –inflammatory effect of curcumin has been compared to that of the common and effective anti -inflammatory drugs such as hydrocortisone and phenylbutazone. The good thing is that though they may have similar actions, curcumin does not have the toxic effects associated with those drugs such as ulcer formation, leucopenia and intestinal bleeding.

Curamed supplement contains proprietary complex which can provide an enhanced bioavailability and constant retention time inside the body. It is formulated using a distinctive and patented process so that it can deliver the anti – inflammatory ingredient curcumin to the body 1000%. The patented process also allows the chemicals to be inside the body for about 8 to 12 hours. Curamed is clinically studied and proven with the help of intensive research. In addition, Curamed has also been found to be an effective liver detoxifier and protectant.

Other ingredients containing the Curamed supplement include triglycerides, glycerin phosphatidylcholine lecithin, purified water and beeswax. It contains only natural ingredients and has no sugar therefore it is safe for diabetic patients and those who are under weight loss programs. It also contains no salt and gluten making it safe for cardiovascular disease and Celiac disease patients, respectively. Each product container contains 30, 60 or 120 750 milligram – soft gel. It is made available in health food stores, drug stores and even Online. Make sure to check labels before purchasing since there are many imitations and fraud.

Recommended dosage depends on the individual’s age, gender, pain threshold, health condition and other related factors. The recommended dosage is usually one to two soft gels everyday. Give Curamed a try and feel the difference!

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Buckthorn Of The Sea
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Date: August 05, 2009 04:05 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Buckthorn Of The Sea

Sea buckthorn is also known as sea berry or Siberian pineapple. It is a small shrub that can be found growing natively in a wild swath across Europe and Asia. This plant has been used by southeast Asians to treat various diseases for hundreds of years. The ancient Greeks are believed to have used the berries of the sea buckthorn plant in order to promote weight gain and shiny fur in horses.

After analyzing the orange berries of sea buckthorn, an abundance of vitamins C and E, carotenoids, flavonoids, glucose, fructose, several amino acids, and fatty acids have been found. The berries of this herb are used in order to produce juices, jams, liquors, and lotions. The oil that comes from the berries of sea buckthorn has been used to treat ailments that are related to inflammation. Included in these ailments are canker sores, esophagitis, cervicitis, peptic ulcers, and ulcerative colitis. Horticulturalists from the Soviet Union and East Germany came up with new varieties of sea buckthorn during the Cold War years that produce bigger berries and better nutrition.

Traditional Chinese medicine uses sea buckthorn to boost energy. Olympic athletes in the country have recently used sea-buckthorn-based sports drinks as part of their training. This herb is used in Russia in ointments to help shield cosmonauts from radiation damage while in orbit. The oil found in sea buckthorn contains high amounts of palmitoleic acid, which is a rare fatty acid that is found in skin fat. This fatty acid aids cell tissue and wound healing. Some U.S. cosmetic firms put this herb into their skin creams in order to provide protectant and anti-aging properties.

Sea buckthorn is recommended by herbalists in order to boost energy levels, promote wound healing, and shield the skin from the damage caused by ultraviolet rays. Some research on the wound-healing and tissue-protecting properties of this herb has provided positive results. The extract was shown to strengthen cardiac pump function and myocardial contractility in animal studies where dogs with heart failure were tested. The herb also seems to improve oxygen use in the hearts of dogs and animal heart cells in test tubes.

Generally, sea buckthorn oils are used externally for burns and other skin damage. They are also used internally for stomach and duodenal ulcers. Anecdotal reports of sea buckthorn extract have shown it being used to fight tumor growth, high blood pressure, and high cholesterol.

The berries of the sea buckthorn plant are used to provide anti-inflammatory properties. The primary nutrients found in this herb are amino acids, carotenoids, fatty acids, flavonoids, fructose, glucose, and vitamins C and E. Primarily, sea buckthorn is extremely beneficial in treating burns, canker sores, cervicitis, colitis, lack of energy, esophagitis, skin protection, ulcers, and wounds. In order to obtain the best results when supplementing with this, or any herb, it is important to consult your health care provider before beginning any regimen while on medications. For more information on the many beneficial effects provided by sea buckthorn, please feel free to consult a representative from your local health food store with questions.

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Capsicum - Cayenne Red Pepper
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Date: July 28, 2008 03:06 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Capsicum - Cayenne Red Pepper

Capsicum also known as cayenne pepper has been known to the natives of the tropical Americas for thousands of years. It was first introduced to Europe by Christopher Columbus as Guinea Pepper and was originally used by Native Americans that were located south of the Mexican boarder as early as 700 B.C. The mixture of chocolate and red chilies was a taste treat that was reserved exclusively for Aztec royalty. Although the exact origin of the word Capsicum is somewhat a mystery, it is assumed to be derived from the Greek word kapto, which means to bite. Capsicum is a fruit found on a shrub-like tropical plant that is technically considered a berry. The designation of it as a pepper can be traced back to Columbus, who compared its hot taste sensation with that, a black pepper.

Gerard referred to Capsicum as extremely hot and dry in 1597 and prescribed it to those with skin and throat infections. The health practitioners of the 1800s used Capsicum to counteract rheumatism, arthritis, depression, and chills. Capsicum was used in the early 1800s as a potent and safe natural stimulant and was believed to be able to treat a large array of diseases. It was first used orally to treat tumors, toothaches, fevers, and respiratory conditions.

This cayenne red pepper was introduced to England by Dr. John Stevens in 1804 when it became the catalyst component in many herbal blends. Additionally, herbal and medical practitioners used Capsicum in order to fight infection and sustain the natural heat that the body produces. After, it became very well known in American dispensatories and pharmacopeia. In 1943, The Dispensary of the United States recorded Capsicum to be a powerful local stimulant that produces a sense of heat in the stomach and a general glow over the whole body when it is swallowed. It does all of this without having a narcotic effect.

Physicians in the twentieth-century recognized the medicinal value of Capsicum. This caused the herb to find its way to the American Illustrated Medical Dictionary, the Merck Manual and Materia Medica, where it is named a rubefacient, local stimulant, counter-irritant, gastric stimulant, and diaphoretic. Mexican Indians today use Capsicum as an intestinal disinfectant and protectant against contaminated food and, additionally, to treat fevers. In the world today, this cayenne pepper is no more appreciated and more widely used than in Mexico and a few other Latin American countries, which together are the original home of all the peppers. Practically every dish the Indians eat both in the morning and evening include Capsicum, just as it was 2,000 years ago. These peppers are a wonderful source of essential vitamins in a diet that is otherwise lacking of them.

Capsicum is a source of health and vitality in many countries which include the Bahamas and Costa Rica, in which it is used to treat colic and indigestion, in Africa for vascular disorders, and in North America as a tonic and natural stimulant. Currently undergoing a large variety of studies, Capsicum has emerged with an impressive list of actions. Scientists are currently taking notice and looking at Capsicum with a new respect and interest. Capsicum can be set apart from powerful pharmaceutical stimulants and pain killers because it possesses the potency without the delirious side effects.



--
Buy Cayenne At Vitanet ®, LLC

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Benefits - Supports joint function and tissue health*
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Date: December 11, 2006 03:46 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Benefits - Supports joint function and tissue health*

To understand glucosamine's role, it is important to understand joint structure and function. Cartilage in the joints acts as a shock absorber to cushion the blows of daily wear and tear. Joint cartilage is made of a unique connective tissue that consists of collagen and proteoglycans. Collagen is a strong, fibrous, insoluble protein. Proteoglycans are large, carbohydrate-rich protein chains made up of 95 percent polysaccharides and 5 percent protein called glycosaminoglycans (GAGs). GAGs are composed of repeating two-sugar units (disaccharides) that contain glucosamine sulfate and other amino sugars. Surrounding the joint cartilage is synovial fluid, which contains many substances including its chief component, hyaluronic acid. Hyaluronic acid forms the backbone of other proteoglycans and is responsible for the thickness of synovial fluid as well as its lubricating and shock-absorbing properties. Synovial fluid also provides nutrients for the joint cartilage.

Glucosamine sulfate is a normal constituent of glycosaminoglycans in cartilage and synovial fluid. In essence, glucosamine sulfate provides important building blocks for cartilage production. Laboratory studies suggest that glucosamine may also function to stimulate production of cartilage-building proteins. It is also thought that the sulfate portion of the molecule contributes to the efficacy of glucosamine sulfate in the synovial fluid by providing the elemental sulfur needed for strengthening cartilage and aiding glycosaminoglycan synthesis. 1,2,3

Glucosamine sulfate has been the subject of research for over twenty years. Clinical trials as well as experimental studies have repeatedly supported the efficacy of oral glucosamine sulfate in supporting joint function. In one large open trial, over 1200 people took oral glucosamine sulfate for periods ranging from 36 to 64 days. In this multi-center trial, ninety-five percent of the subjects experienced greater joint comfort and increased mobility. The physicians reported "good" results in 59%, and "sufficient" results in 36%. Furthermore, the improvements in joint health lasted for up to three months after the glucosamine sulfate was discontinued. 3

Promotes optimal joint comfort, function and flexibility*

Boswellia serrata (Indian frankincense) has been used for centuries in the Indian Ayurvedic system of medicine to maintain healthy joints. Even today, this is one of the primary uses for this plant in Ayurvedic medicine. Boswellic acids have been shown to support healthy joint tissue, maintain circulation to joints, enhance joint mobility, and promote joint comfort in animal models without known side effects. 4

Boswellin® is an extract rich in boswellic acids. Boswellic acids are potent modulators of enzymes involved in leukotriene synthesis in vitro, promoting a healthy balanced production of these components of the immune system.5 Healthy leukotriene balance can lead to enhanced joint function. A human clinical study was conducted to assess the effects of supplementation with a formula containing Boswellia, Curcumin and other nutrients on joint function. In this double-blind placebo-controlled crossover trial, participants were randomly assigned to receive the herbal formulation or a placebo for 3 months. Following this 3-month period, the treatments were reversed for an additional 3 months. The results showed that while each group was receiving the herbal formulation, they had superior joint function and a greater sense of joint comfort when compared to the placebo groups.6 Other trials lend further support to Boswellia’s ability to promote healthy joint function.4,6,7

Curcumin is a potent antioxidant that has known free radical scavenging activity. This activity of Curcumin is thought to play a major part in its role as a joint protective nutrient. In fact, the numerous beneficial effects attributed of whole turmeric are thought to stem in large measure from the antioxidant properties of curcuminoids. Antioxidants neutralize free radicals, which are highly unstable molecules that can damage cellular structures through abnormal oxidative reactions. Curcumin is not toxic to cells, even at high concentrations. Pure Curcumin was shown to be less protective than a mixture of curcuminoids, indicating a possible synergism among the curcuminoids.8

Curcumin demonstrates several other in vitro effects linked to free radical scavenging. Curcumin scavenges nitric oxide, a compound associated with the body’s inflammatory response.9 Curcumin also demonstrates in vitro inhibition of certain enzymes involved in promoting inflammatory reactions in the body. Together these results strongly suggest that Curcumin is a potent bioprotectant with a potentially wide range of therapeutic applications.9,10,11

Preliminary human trials have assessed the therapeutic potential of Curcumin, with results that verify the traditional use of turmeric as an herb to enhance joint health. In a short-term double-blind, cross-over, comparative study, eighteen people were randomized to receive Curcumin (1200 mg daily) or an alternative therapy for two-week periods. The participants in the Curcumin groups were shown to produce measurable enhancements in joint flexibility and walking time.12 Research suggests that Curcumin and Boswellia work extremely well in combination to benefit joint health and mobility, as trials combining both nutrients have yielded highly positive results.

Bioperine-Nature’s Absorption Enhancer Boosts Nutrient Absorption*

Traditional Ayurvedic herbal formulas often include black pepper or long pepper as synergistic herbs. The active ingredient in both black pepper and long pepper is the alkaloid, piperine. Experiments carried out to evaluate the scientific basis for the use of peppers have shown that piperine significantly enhances bioavailability when consumed with other substances.13 Several double-blind clinical studies have confirmed that Bioperine® increases absorption of nutrients.14

Curcumin is known to be poorly absorbed in the intestinal tract when used on its own, thereby limiting its therapeutic effectiveness. Oral doses are largely excreted in feces, and only trace amounts appear in the bloodstream. However, a study has shown that concomitant administration of 20 mg of piperine with 2 grams of Curcumin was able to enhance Curcumin bioavailability by an astounding 2000%. 15 These results speak to the wisdom of including a small amount of Bioperine® in the formulation to ensure nutrient bioavailability.

Sustained Release – For lasting joint comfort and convenient dosing

To ensure that the body can utilize all of the joint health-enhancing nutrients effectively, Best Joint Support featuring ArthriBlend-SR™ has been designed to have a sustained release delivery system. The nutrients are released over a longer period of time, maximizing absorption and providing the comfort-enhancing properties in a sustained manner. This unique delivery system allows the product to be taken just twice daily while maintaining its efficacy throughout the day.

Safety

Suggested Adult Use: Take two tablets every 12 hours. Take 4 tablets daily.

Scientific References
1. Vidal y Plana, R.R., Bizzarri, D., Rovati, A.L. Articular cartilage pharmacology: I. In vitro studies on glucosamine and non-steroidal antiinflammatory drugs. Pharmacological Research Communications 1978; 10(6):557-569.

2. Tapadinhas M.J., Rivera, I.C. Bignamini, A.A. Oral glucosamine sulphate in the management of arthrosis: report on a multi-centre open investigation in Portugal. Pharmatherpeutica 1982; 3(3):157-68.

3. Vaz, A.L. Double-blind clinical evaluation of the relative efficacy of ibuprofen and glucosamine sulphate in the management of osteoarthrosis of the knee in out-patients. Current Medical Research and Opinion 1982; 8(3):145-149.

4. Kimmatkar N, Thawani V, Hingorani L, Khiyani R. Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee--a randomized double blind placebo controlled trial. Phytomedicine. 2003 Jan;10(1):3-7.

5. Safayhi, H., Mack, T., Sabieraj, J., Anazodo, M.I., Subramanian, L.R., and Ammon, H.P.T. (1992) Boswellic acids: Novel, specific, nonredox inhibitors of 5-lipoxygenase. J. Pharmacol. Exp. Ther. 261(3), 1143-1146.

6. Boswellia serrata. Alternative Medicine Review Monographs – Volume One. 2002.

7. Kulkarni RR, Patki PS, Jog VP, Gandage SG, Patwardhan B. Treatment of osteoarthritis with a herbomineral formulation: a double-blind, placebo-controlled, cross-over study. J Ethnopharmacol. 1991 May-Jun;33(1-2):91-5.

8. Majeed, M., Badmaev, V., Shivakumar, U., Rajendran, R. Curcuminoids: Antioxidant Phytonutrients. 1995. Piscataway, NJ: NutriScience Publishers.

9. Snow, J.M. Herbal Monograph: Curcuma longa L. (Zingiberaceae). The Protocol Journal of Botanical Medicine, Autumn 1995:43-46.

10. Rao, S., Rao, M.N.A. Nitric oxide scavenging by curcuminoids. J Pharm. Pharmacol. 1997;49:105-7.

11. Ramsewak, R.S., DeWitt, D.L., Nair, M.G. Cytotoxicity, antioxidant, and anti-inflammatory activities of Curcumins I-III from Curcuma longa. Phytomedicine 2000;7(4):303-308.

12. Deodhar, S.D., Sethi, R. Srimal. R.C. Preliminary study on antirheumatic activity of curcumin (diferoyl methane). Indian J Med Res 1980;71:632-34.

13. Atal, C., Zutshi, U., Rao, P. Scientific evidence on the role of Ayurvedic herbals on bioavailability of drugs. Journal of Ethnopharmacology 1981;4:229-232.

14. Bioperine®–Nature's Bioavailability Enhancing Thermonutrient. Executive Summary. 1996; Sabinsa Corporation, Piscataway, N.J.

15. Shoba, G., et al. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Medica 1998;64(4):353-6.



--
for Great Joint Health buy Best Joint Support at Vitanet

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Curcumin - Turmeric Extract
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Date: August 19, 2005 12:47 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Curcumin - Turmeric Extract

Curcumin

Turmeric- History and Traditional Usage

Native to Southeast Asia, Curcuma longa is a tall
tropical shrub with large oblong leaves and pale yellow flowers.
The genus “Curcuma” belongs to the Zingiberaceae family, which
includes ginger.1 The plant possesses a large root structure
with fleshy, bulbous underground parts called “rhizomes.” These
rhizomes, known as turmeric root, are harvested at maturity,
dried and cured for commercial use. Chemical analysis shows that
dried turmeric contains essential and volatile oils, with a
curcuminoid content of 2.5 to 5.0 %.2

In addition to its
popularity as a spice, turmeric is used as a dye for cloth and
coloring agent in foods and cosmetics, thanks to its rich yellow
color. Turmeric also serves as a preservative, probably owing to
the antioxidant and antimicrobial properties of curcumin.
Extracts of Curcuma longa have demonstrated in vitro
antibacterial and anti-fungal effects.3

Turmeric is named in
ancient Ayurvedic and Chinese herbal texts as a traditional folk
remedy. Historically, turmeric was used externally for wounds,
and sprains, and internally for digestive complaints,
rheumatism, liver disorders, coughs and colds.4
Benefits

Protects cells and tissues by fighting free radicals.*

Supports joint function*

The numerous beneficial
effects attributed to turmeric stem in large measure from the
antioxidant properties of curcumin. Antioxidants neutralize free
radicals, which are highly unstable molecules that can damage
cellular structures through abnormal oxidative reactions.
Curcumin is a potent “scavenger” of the superoxide radical, a
free radical that initiates potentially harmful oxidative
processes such as lipid peroxidation.5 Through this activity,
curcumin has been shown to protect skin cells from the injurious
effect of nitroblue tetrazolium, a toxin that generates
superoxide radicals. Curcumin also increases survival of cells
exposed in vitro to the enzyme hypoxanthine/xanthine oxidase,
which stimulates superoxide and hydrogen peroxide production.
Curcumin itself is not toxic to cells, even at high
concentrations. Pure curcumin was shown to be less protective
than a mixture of curcuminoids, indicating a possible synergism
among curcuminoids.6 Because free radicals are involved in aging
and exert harmful effects on skin, these results suggest
curcumin may help slow skin aging.

Curcumin demonstrates
several other in vitro effects linked to free radical
scavenging. Curcumin scavenges nitric oxide, a compound
associated with the body’s inflammatory response.7 Pure curcumin
and turmeric extracts protect red blood cells from lipid
peroxidation induced by hydrogen peroxide.8 Curcumin has been
shown to protect DNA from oxidative damage, inhibit binding of
toxic metabolites to DNA, and reduce DNA mutations in the Ames’
test.9 Although additional studies suggest an anticarcinogenic
effect of curcumin, through protection of DNA,10 one in vitro
study found that curcumin induced DNA damage in human gastric
mucosal cells.11 It is speculated that curcumin may act as a
pro-oxidant in the presence of transition metal ions such as
copper and iron. (This is true for other antioxidants, including
vitamin C.) Curcumin also demonstrates in vitro inhibition of
COX-I and COX-II enzymes, which are involved in the inflammatory
reaction.12 Together these results strongly suggest that
curcumin is a potent bioprotectant with a potentially wide range
of therapeutic applications.

Animal studies- In vivo protective effects

Through its free radical scavenging
properties, curcumin has shown bioprotective effects in animals.
In one study, rats were treated with isoproterenol, a chemical
that causes cardiac hypertrophy (enlargement of the heart) due
to abnormal collagen metabolism. Co-treatment with curcumin
reversed the degradation of collagen and cardiac hypertrophy
induced by isoproterenol.13 Curcumin protects mice from
detrimental effects of radiation, by stabilizing the glyoxalase
system, a biological system that regulates cell division.14
Curcumin protects livers of rats from the damaging effects of
carbon tetrachloride (CCl4), a potent hepatoxin that injures the
liver via its free radical metabolite, CCl3.15,16 Curcumin
protected rats from alcohol-induced brain damage, in a study in
which oral administration of curcumin reversed lipid
peroxidation, reduced levels of free-radical metabolites and
increased levels of glutathione, a major physiologic
antioxidant.17 Curcuma longa extracts have shown
anti-inflammatory effects in rats.18

Human Trials

Curcumin exhibits free-radical scavenging ability when
administered to humans. In an open trial (uncontrolled), 18
healthy individuals ranging in age from 27 to 67 years consumed
a Curcuma longa extract, at a dose supplying 20 mg curcuminoids,
for 45 days. Before and after blood tests showed a statistically
significant decrease in lipid peroxides.19 Preliminary trials
have tested the anti-inflammatory action of curcumin, with
results that verify the traditional use of turmeric as an
anti-rheumatic herb. In a short-term double-blind, cross-over,
comparative study, 18 people received curcumin (1200 mg daily)
or phenylbutazone for two week periods. Both curcumin and
phenylbutazone produced measurable improvements in joint
flexibility and walking time. The subjects reported results only
with phenylbutazone, which may be explained by the short
duration of the trial.20 In a small placebo-controlled trial
comparing curcumin to phenylbutazone, 45 patients with
post-operative inflammation received curcumin, phenylbutazone or
placebo. The anti-inflammatory effects of curcumin and
phenylbutazone were comparable and superior to placebo.21
Curcumin has not been found to produce an analgesic (pain
relieving) effect.

Bioperine-Nature’s Absorption Enhancer
Boosts Curcumin Absorption*

Traditional Ayurvedic herbal
formulas often include black pepper and long pepper as
synergistic herbs. The active ingredient in both black pepper
and long pepper is the alkaloid, piperine. Experiments carried
out to evaluate the scientific basis for the use of peppers have
shown that piperine significantly enhances bioavailability when
consumed with other substances.22 Several double-blind clinical
studies have confirmed that Bioperine® increases absorption of
nutrients.23

Curcumin is poorly absorbed in the intestinal
tract, limiting its therapeutic effectiveness. Oral doses are
largely excreted in feces, and only trace amounts appear in the
blood. Concomitant administration of 20 mg of piperine with 2
grams of curcumin increases the bioavailability of curcumin by
2000%.24

Scientific References


1. Majeed, M., Badmaev,
V., Shivakumar, U., Rajendran, R. Curcuminoids. 1995.
Piscataway, NJ: NutriScience Publishers.
2. Srimal, R.C.
Turmeric: a brief review of its medicinal properties.
Fitoterapia 1997;68(6):483-93.
3. Ammon, H.P.T., Wahl, M.A.
Pharmacology of Curcuma longa. Planta Medica 1991;57:1-7.
4.
Snow, J.M. Herbal Monograph: Curcuma longa L. (Zingiberaceae).
The Protocol Journal of Botanical Medicine, Autumn
1995:43-46.
5. Rao, N.S., Rao, M.N.A. Free radical scavenging
activity of curcuminoids. Arzneim.-Forsch./Drug Res.
1996;46(2):169-171.
6. Bonté. F. et al. Protective effect of
curcuminoids on epidermal skin cells under free oxygen radical
stress. Planta Medica 1997;63:265-66.
7. Rao, S., Rao, M.N.A.
Nitric oxide scavenging by curcuminoids. J Pharm. Pharmacol.
1997;49:105-7.
8. Lalitha, S., Selvam, R. Prevention of
H2Os-induced red blood cell lipid peroxidation by aqueous
extracted turmeric. Asia Pacific J Clin Nutr
1999;8(2):113-14.
9. Deshpande, S.S., Maru, G.B. Effects of
curcumin on the formation of benzo[a]pyrene derived DNA adducts
in vitro. Cancer Letters 1995;96:71-80.
10. Subramanian, M., et
al. Diminution of singlet oxygen-induced DNA damage by curcumin
and related antioxidants. Mutation Research
1994;311:249-55.
11. Blasiak, J., Trzeciak, A., Kowalik, J.
Curcumin damages DNA in human gastric mucosa cells and
lymphocytes. Journal of Environmental Pathology, Toxicology and
Oncology 1999;18(4):271-76.
12. Ramsewak, R.S., DeWitt, D.L.,
Nair, M.G. Cytotoxicity, antioxidant, and anti-inflammatory
activities of Curcumins I-III from Curcuma longa. Phytomedicine
2000;7(4):303-308.
13. Nirmala, C. Anand, S., Puvanakrishnan,
R. Curcumin treatment modulates collagen metabolism in
isoproterenol induced myocardial necrosis in rats. Molecular and
Cellular Biochemistry 1999;197:31-37.
14. Choudhary, D.,
Chandra, D. Kale, R.K. Modulation of radioresponse of glyoxalase
system by curcumin. Journal of Ethnopharmacology
1999;64:1-7.
15. Park, E-J. et al. Protective effect of
curcumin in rat liver injury induced by carbon tetrachloride. J
Pharm. Pharmacol. 2000;52:437-40.
16. Deshpande, U.R. et al.
Protective effect of turmeric (Curcuma longa L.) extract on
carbon tetrachloride-induced liver damage in rats. Indian
Journal of Experimental Biology 1998;36:573-77.
17.
Rajakrishnan, V. et al. Neuroprotective role of curcumin from
Curcuma longa on ethanol-induced brain damage. Phytotherapy
Research 1999;13:571-74.
18. Arora, R.B. Basu, N., Kapoor, V.,
Jain, A.P. Anti-inflammatory studies on Curcuma longa
(Turmeric). Indian J Med Res 1971;59(8):1289-95.
19.
Ramirez-Bosca, A. et al. Antioxidant curcuma extracts decrease
the blood peroxide levels of human subjects. Age
1995;18:167-69.
20. Deodhar, S.D., Sethi, R. Srimal. R.C.
Preliminary study on antirheumatic activity of curcumin
(diferoyl methane). Indian J Med Res 1980;71:632-34.
21.
Satoskar, R.R., Shah, S J. Shenoy, S.G. Evaluation of
anti-inflammatory property of curcumin (diferoyl methane) in
patients with postoperative inflammation. International Journal
of Clinical Pharmacology, Therapy and Toxicolgy
1986;24(12):651-54.
22. Atal, C., Zutshi, U., Rao, P.
Scientific evidence on the role of Ayurvedic herbals on
bioavailability of drugs. Journal of Ethnopharmacology
1981;4:229-232.
23. Bioperine®–Nature's Bioavailability
Enhancing Thermonutrient. Executive Summary. 1996; Sabinsa
Corporation, Piscataway, N.J.
24. Shoba, G., et al. Influence
of piperine on the pharmacokinetics of curcumin in animals and
human volunteers. Planta Medica 1998;64(4):353-6.

© 2002
Doctor's Best, Inc. Revised 8/13/02

*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.



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WHAT EXACTLY IS PYCNOGENOL?
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Date: July 13, 2005 09:42 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: WHAT EXACTLY IS PYCNOGENOL?

WHAT EXACTLY IS PYCNOGENOL?

Pycnogenol is a super antioxidant which consists of a highly bioavailable flavonoid called proanthocyanidin. This compound can be extracted from either pine bark or grape seed, and both sources are virtually identical. Biochemists will confirm that as a class, the proanthocyanidin bioflavonoids, regardless of their source, possess the same biochemical activity with very slight exceptions.

The differences lie in the varying concentrations of the flavonoid and its purity. Extraction processes for each source d i ffer and may contribute to the cost of the type of Pycnogenol in question. Regardless of its source, Pycnogenol has demonstrated extraordinary antioxidant capabilities.

NATURE’S BEST DEFENSE AGAINST FREE RADICALS: ANTIOXIDANTS

Potent substances called antioxidants, which scavenge for dangerous free radicals, afford us the best prospect for disease prevention, toxin protection and sustained longevity and vigor. According to many experts, making sure we arm our cellular systems with adequate supplies of antioxidants should be our first health priority. “It has now been established that more than 60 human diseases involve free-radical damage, including cancer, heart disease and the acceleration of the aging process. All that you really need to know is that your body is under constant free - radical atta ck, and that you need to keep your antioxidant defenses strong.”1 The role of Pycnogenol as an exc e ptional free radical scavenger is just beginning to emerge, and the protective potential of Pycnogenol is impressive, to say the least. It’s only a matter of time before scientific data supports the fact that this family of nutrients is far more effective in its antioxidant capacity than previously assumed.

OTHER ANTIOXIDANTS

Some of the most common of free radical scavengers or antioxidants include:

  • • Vitamin E
  • • Vitamin C
  • • Vitamin A and Beta Carotene
  • • Coenzyme Q-10
  • • Selenium

    While all of these are excellent cellular protectants, the compound missing from the above list may be the most remarkable of all.

    PYCNOGENOL: THE HERCULES OF ANTIOXIDANTS

    Pycnogenol provides some of the most potent compounds known to nutritionally support and potentiate the body’s defense system against oxidants. Continually emerging research supports the fact that Pycnogenol may be the best antioxidant nature has to offer. In this regard, it is 50 times more potent than vitamin E and 20 times more so than vitamin C.2 Pycnogenol is considered by some health experts to be the greatest nutritional breakthrough of our century.

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    MILK THISTLE: A VITAL COMPONENT OF LIVER REHABILITATION
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    Date: July 12, 2005 10:01 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: MILK THISTLE: A VITAL COMPONENT OF LIVER REHABILITATION

    MILK THISTLE: A VITAL COMPONENT OF LIVER REHABILITATION

    In addition to the flavonoid-like components of Silymarin, Milk Thistle seeds also contain betaine, which has proven itself as a liver protectant. Additionally, essential fatty acids are found in Milk Thistle which help control chronic inflammation.7

    Milk Thistle should be a vital part of any therapeutic program designed to treat liver disorders. It can provide liver protection after exposure to radiation, heavy metals or toxic chemicals. Anyone who has hepatitis or cirrhosis should be using this herb as part of their treatment regimen. Concerning Milk Thistle and the liver, Christopher Hobbs wrote:

    “I first learned of Milk Thistle in early 1984, when I began harvesting seeds from wild plants growing in California and taking the liquid extract I made from them. I had sustained heavy damage to my liver as a result of having hepatitis twice, in 1963 and in 1967, and I was able to greatly restore my digestive power with the help of this herb. Since then, I have witnessed other surprising recoveries from severe liver ailments with the use of this herb.”8

    There is no question that the Silymarin compounds of Milk Thistle have significant therapeutic value for liver diseases of various kinds including: hepatitis, fatty infiltration of the liver, cirrhosis, and inflammation of the bile duct.9

    The tyramine and histamine content of Milk Thistle works to stimulate the production and flow of bile, which also benefits the liver. A whole host of laboratory tests from biopsies to clinical data confirm that Silymarin is particularly effective in treating and preventing liver damage from alcohol abuse or chemical exposure. Extensive clinical trails have clearly shown that Milk Thistle can reverse the symptoms of many liver disorders.

    In addition, Milk Thistle can exert a therapeutic effect on chronic hepatitis, cirrhosis, fatty infiltration of the liver, cholestasis of pregnancy, cholangitis and pericholangitis.10 While the liver has a great capacity for regeneration, when it is diseased or damaged by toxins like alcohol, it can cease to produce badly needed liver cells. Milk Thistle can stimulate this proliferation. The earlier it is taken, the quicker recovery will be.

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    HISTORY
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    Date: July 12, 2005 09:52 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: HISTORY

    HISTORY or Milk Thistle

    Natural substances which afford us protection from toxins and potential carcinogens have recently come to the fore front of scientific attention. Compounds known as antioxidants, which can help minimize the damaging effects of chemical stru c t u res called free radicals, are extensively used today. One of these protectant substances is not as familiar to most people as vitamin C or beta-carotene. It is an herb called Milk Thistle and it has some extraordinary protective properties. Milk Thistle, also known as Silymarin has enjoyed a long history of use in European folk medicine. Centuries ago, Romans recognized the value of this herb for liver impairments. They routinely used the seeds and roots of the plant to restore and rejuvenate a diseased liver. Pliny the Elder, an ancient Roman, re c o rded how the juice of Milk Thistle, when mixed with honey was used for carrying off bile. Dioscorides extolled the virtues of Milk Thistle as an effective protectant against snake bites. The genus silybum is a member of the thistle tribe of the daisy family. Two species of the plant exist and both are native to southern Europe and Eurasia. Plants which grow in the Southern United States actually have more potent seeds than their European and Asian counterparts. Milk Thistle is a stout and sturdy looking plant, which can grow up to 12 feet tall. The flower heads can expand to six inches in diameter and are a vivid purple color. They usually bloom from June to August. Very sharp spines cover the heads. The leaves are comprised of hairless, milky bands, and when young, are quite tender. Historically, the seed of Milk Thistle was used as a cholagogue which stimulated the flow of bile. The seed was also used to treat jaundice, dyspepsia, lack of appetite and other stomach disorders. Homeopathic uses included:

    peritonitis, coughs, varicose veins and uterine congestion. While tonics were sometimes made from the leaves of Milk Thistle, the most valuable part of the plant was contained in its seeds.

    Milk Thistle is also known as Marian Thistle, Wild Artichoke, Variegated Thistle or St. Mary’s Thistle. Reference to Milk Thistle as “Vi rgin Mary” stems from its white milky veins. Legends explained that these veins were created when Mary’s milk fell on the thistle. Subsequently, a connection between the herb and lactation arose, which has no scientific basis for its claims. Milk Thistle is frequently confused with Blessed Thistle, which does act to stimulate the production of mother’s milk. Gerarde, a practicing herbalist in 1597, said that Milk Thistle was one of the best remedies for melancholy (liver related) diseases. In 1650, Culpeper wrote of its ability to remove obstructions in the liver and spleen. In 1755, Von Haller recorded that he used Milk Thistle for a variety of liver disorders. Subsequently, Milk Thistle became a staple agent for the treatment of any kind of liver aliment. European physicians included it in their written materia medica. Unfortunately, for an extended period during the 18th century, the herb was not stressed, however in 1848, Johannes Gottfried Rademacher rediscovered its medicinal merits. He recorded in great detail how Milk Thistle treated a number of liver ailments and spleen disorders. His research was later confirmed in medical literature. In the early 20th century, Milk Thistle was recommended for female problems, colon disorders, liver complaints and gallstones. Almost every significant European pharmaceutical establishment listed Milk Thistle as a valuable treatment. In recent decades, Milk Thistle has been primarily used as a liver tonic and digestive aid. Nursing women who wanted to stimulate the production of their milk used Milk thistle as a traditional tonic. As mentioned earlier, modern day medical science now refutes this particular action of Milk Thistle, however, its benefit to the liver has been confirmed.

    German herbalists have routinely used Milk Thistle for treating jaundice, mushroom poisoning and other liver disorders. This therapeutic tradition contributed to modern German research into Milk Thistle, resulting in its use as a widely prescribed phytomedicine for liver disease. Silymarin or Thisilyn, as it is also known, is a relatively new nutrient in the United States. Since 1954, scientists have known the Milk Thistle contained flavonoids, however, it wasn’t until the 1960’s that they discovered the just how unique silymarin is. Silymarin was considered an entirely new class of chemical compound, and its therapeutic properties continue to impress the scientific community.

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    HISTORY
    TopPreviousNext

    Date: June 25, 2005 09:58 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: HISTORY

    HISTORY

    For thousands of years amazing magical and medicinal powers have been attributed to garlic. Prized as a legendary protectant against vampires in Transylvania, it has also been used to enhance sexual prowess and fight off infections. Referred to as “the stinking rose,” it is mentioned in Bible, the Talmud, and in the Odyssey by Homer as well. The Egyptians looked to garlic as a tonic which boosted physical strength and consumed it while building the pyramids. The Greeks utilized its laxative properties, and the Chinese prescribed it for high blood pressure. Vikings and Phoenicians alike extolled the virtues of garlic and used it both for flavoring foods and treating disease.

    Garlic is a hardy, perennial bulb which is native to the Mediterranean regions of Africa and Europe. Along with onions, leeks, chives and shallots, garlic is a member of the lily family. The botanical name for garlic, allium sativum may have been derived from the celtic word all which refers to “pungent.” The edible portion of the garlic plant grows underground and consists of a cloved bulb.

    Hippocrates believed that garlic could treat uterine cancer and Native Americans used it for stomach cancer. During the Bubonic Plague years in Europe, garlic was used to boost immunity against the infectious organism responsible for so many deaths. Several accounts relate that survivors of the plague were frequently those who had routinely ingested large amounts of garlic. A sixteenth- century herbalist writes, referring to garlic, “The virtue of this herb is thus. It will unbind all wicked winds within a man’s body.”1

    During the eighteenth century, Russians utilized garlic to treat influenza. Eventually, garlic would become known as “Russian penicillin.” American colonists regarded garlic for its ability to kill parasites.

    In the nineteenth century, Louis Pasteur finally proved scientifically that garlic contains antibiotic properties. His discovery led to the initiation of hundreds of studies which have substantiated his findings. What was thought to be nothing more than a culinary ingredient has medicinal value. Garlic can effectively kill bacteria, fungi, viruses and parasites. In the late nineteenth century, garlic was routinely used by physicians as an effective treatment for typhus, cholera and whooping cough. It was highly recommended by medical practitioners and considered as staple treatment for infection. Albert Schweitzer used garlic for treating amebic dysentery in Africa. Early in this century, tuberculosis was treated with garlic and it was also used as an antibiotic/antiseptic for wounds during World War II. American and European doctors alike noted a remarkable high cure rate in tuberculosis patients treated with garlic.

    2 Septic poisoning and gangrene, which can so quickly develop in battlefield wounds were prevented to a significant degree by using garlic. During the 1950’s Chinese scientists used garlic to successfully treat influenza. Subsequently, western studies found that garlic was an effective treatment for the common cold. Today the widespread use of antibiotics have relegated garlic to the back burner of medicinal therapies for infection. The discovery of penicillin resulted in classifying garlic as nothing more than a folk remedy. Unfortunately, for several decades its medicinal potential was no longer taken seriously by scientists. Over the last decade, scientific interest in garlic has dramatically escalated. In 1990, the First World Congress on the Health Significance of garlic and Garlic Constituents was held in Washington D.C. Herbalists have always considered garlic as an effective treatment and preventative agent against colds, flu and other infectious diseases. The present focus on garlic as a medicinal agent promises to support the notion that garlic should be utilized by medical practitioners much more than it currently is.

    Recently, medical research has focused on garlic’s potential value in treating cardiovascular disorders and as an anti-cancer agent. This renewed interest in garlic has contributed to the development of the “Designer Foods Program” which is sponsored by the National Cancer Institute.3 This agency investigates foods that may be effective cancer preventatives. Garlic is one of those foods which may have profound cancer prevention potential.

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    HISTORY
    TopPreviousNext

    Date: June 23, 2005 10:53 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: HISTORY

    HISTORY

    Known to the natives of the tropical Americas for millennia, Capsicum, or Cayenne Pepper, was introduced to Europe by Christopher Columbus and became known as “Guinea Pepper. ” Originally used by Native Americans located south of the Mexican border, archeological evidence supports its cultivation from 7000 B.C. Apparently, mixing chocolate and red chiles was a taste treat exclusively reserved for Aztec royalty.5 The exact origin of the word Capsicum remains somewhat of a mystery. However, it is assumed to be a derivative of the Greek word kapto, meaning “to bite,” an appropriate reference to its fiery pods. Capsicum is the fruit of a shrub-like tropical plant and is technically considered a berry. Its designation as a “pepper” can be traced back to Columbus, who equated its hot taste sensation with that of black pepper.

    In 1597, Gerard referred to Capsicum as extremely hot and dry and prescribed it for throat and skin infections. Health practitioners of the nineteenth century called phsysiomedicalists used Capsicum to counteract rheumatism, arthritis, depression and chills. In the early 1800s, Dr. Samuel Thompson utilize d Capsicum as a potent and safe natural stimulant. His followe r s , who would become known as Thomsonians, believed that Capsicum should be used to treat a wide variety of diseases. It was used orally and as a poultice to treat tumors, toothaches, feve r s , and respiratory ailments.

    In 1804, Dr. John St e vens introduced the red pepper to England where it became the catalyst component in a variety of herbal blends. Subsequently, herbal and medical practitioners used Capsicum to fight infection and sustain the natural heat of the body. It became well known in American dispensatories and pharmacopeia. In 1943, The Dispensary of the United States recorded that, “Capsicum is a powe rful local stimulant, producing when CAPSICUM swallowed, a sense of heat in the stomach and a general glow over the body without narcotic effect.”6 Twentieth-century physicians recognized the medicinal value of Capsicum which eventually found its way to the American Illust rated Medical Dictionary, the Merck Manual and Materia Medica, where it was referred to as a rubefacient, local stimulant, counter-irritant, gastric stimulant, and diaphoretic.7

    Today Mexican Indians continue to use Capsicum as an internal disinfectant and protectant against contaminated food and also to treat fevers.8 “Today the pepper is nowhere in the world more appreciated and more widely used than in Mexico and certain other Latin American countries, which together form the original home of all the peppers. Both at morning and at evening, practically eve ry dish the Indians eat included Capsicum, just as their food did 2,000 years ago. The diet of the Indians was, and still is, rather bland . . . maize, beans, squash, pumpkin, yucca, potatoes . . . little wonder that the pepper was so highly regarded. And of course . . . the peppers were a wonderful source of essential vitamins in a diet otherwise lacking in them.”9 Capsicum continues to be a source of vitality and health in numerous countries including the Bahamas and Costa Rica, where it is used to overcome colic or indigestion, in Africa for vascular disorders and by North Americans who use it as a tonic and natural stimulant.

    Capsicum is currently experiencing a renaissance in that a number of recent studies have emerged adding to its already impressive list of actions. Scientists are taking notice and looking at Capsicum with new respect and interest. Perhaps what sets Capsicum apart is that unlike powe rful pharmaceutical stimulants and pain killers, Capsicum possess potency without deleterious side effects.

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    GPC (GlyceroPhosphoCholine) Versatile Life Support Nutrient ....
    TopPreviousNext

    Date: June 21, 2005 05:25 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: GPC (GlyceroPhosphoCholine) Versatile Life Support Nutrient ....

    GPC (GlyceroPhosphoCholine): Versatile Life Support Nutrient

    Parris Kidd, Ph.D.

  • GPC - Marked Benefits to the Brain
  • GPC Supports Normal Brain Function
  • GPC Works Through Multiple Mechanisms
  • Dosing, Safety, Tolerability, Compatibility
  • GPC: Nutrient for All Ages
  • GPC or GlyceroPhosphoCholine (pronounced gli-sero-fos-fo-ko-lean) is a nutrient with many different roles in human health. It reaches extremely high concentrations within our cells, and its abundance in mother's milk suggests it is crucial to life processes. Clinically, GPC has been most intensively researched for its brain benefits. Biologically, it has great importance for the skeletal "voluntary" muscles, the autonomic nervous system, kidneys, liver, and reproductive organs. GPC goes beyond being a brain nutrient; it is a nutrient for vitality and long life.

    Marked Benefits to the Brain

    As a dietary supplement, GPC's brain benefits are unique. It boosts mental performance in healthy young people, as shown by three double-blind trials. In trials on middle aged subjects, GPC improved several physiologic measures of mental performance: reaction time, visual evoked potential, and EEG delta slow waves. In the elderly, GPC improves mental performance and provides noticeable revitalisation. In 11 human trials with 1,799 patients, memory, attention, and other cognitive measures improved. So did mood (including irritability and emotional lability), and patients often developed renewed interest in relatives and friends. GPC was well tolerated, and generated no bad drug interactions. A large trial on elderly subjects with memory challenges published in 2003 concluded GPC had significant benefits for these individuals.

    GPC Supports Normal Brain Function

    Circulatory deprivation or surgery can challenge healthy brain function. GPC can speed recovery and support improved quality of life. In four trials with GPC on 2,804 subjects who experienced difficulties under these circumstances, up to 95% showed good or excellent improvement. GPC consistently improved space-time orientation, degree of consciousness, language, motor capacity, and overall quality of life. The investigators concluded GPC offered marked benefits, with an excellent benefit-to-risk profile. Up to half of patients who survive bypass surgery experience problems with memory and other mental performance. A double-blind trial conducted with bypass survivors for six months determined that the GPC group had no remaining memory deterioration, while the placebo group failed to improve.

    GPC Works Through Multiple Mechanisms

    GPC supports human health through a variety of mechanisms:

    1. It helps keep choline and acetylcholine available to the tissues. Choline is an essential nutrient and GPC appears to be the body's main choline reservoir. GPC in mother's milk represents the baby's main source of dietary choline. Acetylcholine (ACh) is an important substance employed extensively throughout the body. ACh is a major brain transmitter; the motor nerves use ACh to drive the skeletal ("voluntary") muscles; the autonomic nervous system uses it to pace all the organs. ACh is also central to mental and physical endurance, and mind-body coordination.

    2. GPC is a major cell-level protectant, not as another antioxidant but in pivotal roles of osmotic pressure regulator and metabolic antitoxin. GPC for osmotic regulation can reach very high concentrations in the kidney, bladder, liver, brain, and other organs. As metabolic protectant, GPC shields proteins against urea buildup.

    3. GPC is a major reservoir for cell membrane omega-3 phospholipids. These substances are the major building blocks for cell membranes. Enzymes couple GPC with the omega-3 fatty acid DHA, to make the phospholipid PC-DHA. This makes membranes especially fluid, enabling membrane proteins to perform with better efficiency. GPC produces PC-DHA in the skeletal muscles, wherein fluidity is essential for contraction. Muscles that function abnormally can show GPC deficiency.

    4. GPC contributes to both male and female in reproduction. As spermatozoa mature, GPC is used to make PC-DHA that makes their membranes fluid to enable motility. With men, the lower their semen GPC the greater the likelihood of poor sperm motility and with it, infertility. Once semen is inserted into the female, an enzyme in uterine secretions breaks down the semen's GPC into substances that energize the sperm to achieve fertilization.

    Dosing, Safety, Tolerability, Compatibility

    Oral intake of GPC in the clinical trials was usually 1,200 milligrams (mg) per day, taken early in the day on an empty stomach. A reasonable dietary supplementation regimen is 1200 mg/day, taken in divided doses (AM and PM) between meals for 15-30 days, and thereafter 600 mg/day for maintenance. Symptomatic subjects can take 1200 mg/day until adequate improvement is achieved. Young, healthy subjects may experience benefit from daily intakes as low as 300 milligrams. GPC is very safe, being compatible with vitamins and nutrients and with pharmaceuticals. In clinical trial comparisons, GPC's benefits surpassed the nutrients acetylcarnitine and CDP-choline.

    GPC: Nutrient for All Ages

    GPC is unmatched for its support of active living and healthy aging. In some 23 clinical trials GPC improved mental performance in all functional categories. GPC can revitalize the aging brain, facilitating growth hormone (GH) release and boosting nerve growth factor actions. GPC's ample presence in human mother's milk suggests it could be conditionally essential. By supporting mental integrity, mind-body integration, the autonomic system, and the body's other organs, GPC enhances the active lifestyle. GPC is remarkable nutritional support for optimal health at any age.

    Parris M. Kidd, PhD is a cell biologist trained at the University of California, Berkeley and San Francisco. Since entering the dietary supplement field in 1983, he has published many in-depth reviews of integrative medicine in the journal Alternative Medicine Reviews, and is science columnist for totalhealth magazine. Dr. Kidd is internationally recognized for his accomplishments in dietary supplement product development, documentation and quality control.

    Disclaimer: the above article is for informational purposes only and is not intended to diagnose or treat a particular illness. The reader is encouraged to seek the advice of a holistically competent licensed professional health care provider.



    --
    Vitanet ®

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    Winter Survival Kit
    TopPreviousNext

    Date: June 13, 2005 07:35 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Winter Survival Kit

    Winter Survival Kit by Joanne Gallo Energy Times, February 4, 2000

    Now that the flesh-baring season is but a distant memory, skin care may have dropped off your list of priorities. But unless you're planning on hibernating until May, Old Man Winter can play a cruel joke on your smooth, glowing complexion-causing cumulative damage not easily remedied. Defend yourself with our survival kit and keep the harsh elements from wreaking havoc on your outer sheath.

    Winter Blast

    Frigid temperatures and blustery winds take their toll on everyone's skin, whether it's normal, oily or dry. Cold dry air, combined with arid indoor heat, results in less natural sebum (oil) production. This oil acts as a protective barrier that helps hold moisture on the surface of the skin; hence less sebum leads to a rough and dry exterior. Icy winds can also cause redness as the stress induces tiny capillaries just underneath the skin's surface to burst.

    So the first order of business for winter skincare is preserving your skin's moisture. Along with external methods of bundling up all exposed areas, dietary habits can help preserve moisture internally.

    Skincare consultant Lynn J. Parentini, author of The Joy of Healthy Skin: A Lifetime Guide to Beautiful, Problem-Free Skin (Prentice Hall), suggests reducing your intake of coffee and tea, which act as diuretics; eating lots of fresh fruits and vegetables, which contain natural, vitamin-rich moisture; and increasing the amount of water you drink (those daily recommended eight glasses of water are even more important in winter).

    A Cleansing Experience

    Bathing can strip skin of its natural oils, so you should be careful of washing with overdrying soaps. Avoid deodorant soaps with harsh detergents which can irritate the skin, and look for milder soaps with moisturizers or a skin-softening shower gel. Neutrogena Rainbath Shower & Bath Gels gently cleanse and condition skin with a rich, full lather that won't leave a residue. Showers tend to be less drying than baths, but if you prefer soaking in a tub you can use bath oil to lubricate the skin. Also avoid very hot showers and baths as they can pull moisture out of the body.

    For extremely dry and sensitive skin, shower at night and follow with a rich moisturizer. Skin then can replenish its protective oils before the morning's icy blast.

    Skin Savers

    Now's the time to use a heavier cream moisturizer to counteract all these dehydrating forces, so finding the right one is imperative. In simpler times, choosing a body moisturizer came down to which one possessed the most pleasing smell. Today, lotions are formulated with nutrients and natural ingredients for powerful, soothing benefits. • CAMOCARE Soothing Cream contains patented Camillosan Camomile, a natural anti-inflammatory. This thick, therapeutic cream is great for dry patches on hands or elbows.

  • • Curel Ultra Protective Concentrated Antioxidant Moisturizer with SPF 15 features an exclusive "cationic technology" that delivers a high level of long-lasting hydration, as well as antioxidants like vitamin E to protect against environmental elements that can cause damage and premature aging.
  • • Nivea Creme, developed in 1911, reportedly smooths roughness even 12 hours after being applied. More than 98% of Nivea's ingredients are natural, and its Eucerit base resembles human sebum.

    Face the Season

    Faces need extra-special protection during winter, as moisturizers do double duty to fight the elements and aging. Many formulas contain alpha (AHA) and beta hydroxy acids: gentle exfoliants that slough off the top layer of dead skin cells to allow younger, smoother-looking skin to emerge. • Oil of Olay's Age Defying Series: Protective Renewal Lotion contains moisturizers, a beta-hydroxy complex, vitamin E and SPF 15. • Neutrogena Healthy Skin Face Lotion is formulated with alpha-hydroxy acids to ease lines, blotches and discoloration; vitamin A and pro-vitamin B5 to increase firmness and moisture levels; and antioxidant vitamins C and E to fight free radical damage and protect new skin.

    Sun Damage

    So you think the sun is the least of your problems in the winter? Better reflect on that matter again. The general public has finally warmed up to wearing sunblock in the summer, but year-round protection against ultraviolet (UV) rays is crucial to avoid premature aging.

    There are two types of UV rays, UVA and UVB: the former are responsible for aging and the latter for burning. Although UVB rays produce a more blatant sign of skin damage, it is limited to the epidermis, or outer layer of the skin.

    UVA rays, on the other hand, don't cause any discomfort, but they penetrate deep to the dermis or second layer of skin. Researchers at the University of Pennsylvania Department of Dermatology have shown that chronic exposure to sunlight can cause holes and breaks in the elastin and collagen fibers that give the skin its shape, definition and supple quality. This damage is what is known as "photoaging." Severely photoaged skin appears dry, scaly, leathery, spotted and deeply wrinkled.

    While the burning UVB rays are most intense during the summer months, UVA rays are prevalent year-round. Their effect on the skin is cumulative, so that the more you're exposed the more likely your skin is to age prematurely. And as only 14% of Americans wear sunscreen year-round (according to the American Academy of Dermatology), most of us are getting more UVA exposure than we realize.

    " New clinical evidence proves that sun damages the skin much faster than previously thought," notes Zoe Draelos, MD, clinical associate professor of dermatology at Wake Forest University School of Medicine. "It only takes small amounts of sun exposure, such as walking to the car or to the mailbox, to start skin damage."

    And for those who engage in popular winter sports like skiing, UVA rays are even stronger at higher elevations. Sunblocks with high SPFs (sun protection factor) guard against UVB rays but they do not block against UVAs, so many sunscreen products do not sufficiently protect against the entire range of UVA rays.

    It is crucial, then, to look for products that guard against the entire spectrum of UVA/UVB rays. Sunblocks that contain zinc oxide, titanium dioxide or Parsol 1789 provide complete protection against aging and burning rays. Try Coppertone Shade UVA Guard SPF 30, Hawaiian Tropic 30 Plus Broad Spectrum Sunblock, L'Oreal Ombrelle Sunscreen Lotion or Spray in SPF 15, or PreSun Ultra SPF 30.

    Lip Tips

    Don't forget that the lips are particularly susceptible to sun damage too. In comparison to other facial skin, they have far fewer oil glands, no sweat glands, a much thinner protective outer layer and very few melanocytes, the cells that produce the protective pigment melanin. Accumulated sun exposure makes the lips less plump as UV rays damage their collagen and elastin fibers, resulting in rough spots, scaly patches or faded areas.

    Even if you wear lipstick on a regular basis, most do not contain the sunscreens and conditioners you can find in a lip balm. Blistex offers a wide range of lip care products, like their new Blistex Herbal Answer, which contains the conditioning qualities of five natural, herbal extracts: aloe, chamomile, avocado, jojoba and shea butter, plus SPF 15; Blistex Ultra Protection with SPF 30 has six protectants for advanced defense against cold, wind and sun; Blistex DCT (Daily Conditioning Treatment) with SPF 20 contains aloe, lanolin, cocoa butter, and vitamins A and E to help keep lips soft and supple. o



    --
    Vitanet ®

    Solaray - Ultimate Nutrition - Actipet Pet supplements - Action Labs - Sunny Greens - Thompson nutritional - Natural Sport - Veg Life Vegan Line - Premier One - NaturalMax - Kal

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    Resveratrol - New Hope for Long Life ...
    TopPreviousNext

    Date: June 06, 2005 08:23 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Resveratrol - New Hope for Long Life ...

    Resveratrol

    We all want to live long, vibrant and healthy lives. At one time intervention in the aging process was regarded as mere fantasy—but today it is within our reach due to breakthroughs in nutritional science. Resveratrol, a compound that is abundant in red wine, has been making headlines recently for its anti-aging potential and its well-documented antioxidant and cardiovascular benefits. Resveratrol has been shown in new research at Harvard Medical School to increase the lifespan of yeast cells—a finding that may help explain the lifeextending effects of the Mediterranean diet. Now Source Naturals offers you RESVERATROL from a non-alcoholic source. RESVERATROL is part of Source Naturals’ extensive line of scientifically based nutrients, designed to help you shape a successful anti-aging program.

    Resveratrol in the News

    Researchers at Harvard Medical School recently made headlines when they identified a plant molecule they believe may hold the key to slowing the human aging process. The compound, resveratrol, is produced by grapevines and other plants in response to environmental stress. The groundbreaking study, reported in the journal Nature, showed that resveratrol mimics the life-extending effects of calorie restriction and increases the lifespan of yeast cells by up to 80%. Resveratrol was found to activate certain enzymes that influence the genes that regulate aging. This research may help explain the long-established association between moderate red wine consumption and cardiovascular health and longevity.

    Wide-Ranging Anti-Aging Benefits

    Previous research has documented resveratrol’s many health benefits:

  • • Resveratrol is a phytoestrogen, which may protect breast, prostate, and endometrial tissue, according to animal and in vitro research.
  • • Resveratrol was found to support healthy mammary and skin tissue in mice by suppressing damaging free radicals.
  • • Resveratrol may support healthy circulation, according to human and animal studies.
  • • Resveratrol has been shown to reduce LDL (bad cholesterol) oxidation and to promote healthy HDL (good cholesterol) levels.
  • • Resveratrol was found to inhibit the Cox-1 and Cox-2 enzymes, which are involved with cellular irritation and cellular growth and regeneration, according to in vitro studies. Recent research focuses on its role in suppressing Cox-2 via the action of NFkappa B, an important DNA regulating factor.

    A Non-Alcoholic Source

    Most publicity about resveratrol focuses on its presence in grape skins and red wine. However, this beneficial compound is found in other plants. Source Naturals RESVERATROL is a standardized extract of Hu Zhang root, a celebrated traditional Chinese herb. This offers consumers the advantage of a non-alcoholic source. Each tablet contains 500 mg of Hu Zhang extract, yielding 40 mg of resveratrol activity. RESVERATROL is available in bottles of 30 or 60 tablets.

    Nature’s Protectant

    Source Naturals, the science company, is pleased to partner with your natural foods retailer in bringing you this botanical treasure. For a long and vital life, RESVERATROL belongs at the center of your anti-aging regimen.

    References:
    Bowers, J.L. et al. 2000. Resveratrol acts as a mixed agonist/antagonist for estrogen receptors alpha and beta. Endocrinol. 141(10):3657-67. Fustier, P. et al. 2003. Resveratrol increases BRCA1 and BRCA2 mRNA expression in breast tumour cell lines. Brit J Cancer. 89(1):168-72. Howitz, Konrad T. et al. Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature. (Published online 8/24/03 in advance of print publication) Jang, M. et al. 1997. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science. 275(5297):218-20. Pace-Asciak C.R. et al. 1996. Wines and grape juices as modulators of platelet aggregation in healthy human subjects. Clin Chim Acta. 246(1-2):163-82.



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    Menopause Multiple - Eternal Woman
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    Date: June 03, 2005 05:54 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Menopause Multiple - Eternal Woman

    Menopause

    Menopause happens to all women, but affects each woman uniquely. For some, the end of fertility (and the end of concerns about contraception) brings a sense of freedom. For others, it is a time of troublesome symptoms or perhaps the need for certain lifestyle adjustments. Menopause is a bridge to a point in life when many women report feeling more confident, empowered and energized than in their younger years. MENOPAUSE MULTIPLE is a Bio-Aligned Formula™ that helps bring alignment to a range of interrelated body systems: hormonal regulation, bone metabolism, cardiovascular health, energy generation and circulation.

    After menopause, the ovaries no longer secrete two critical steroid hormones in the amount or pattern characteristic of a regular menstrual cycle. These two hormones are estrogen and progesterone. The transition from regular ovarian function to its absence is often called the perimenopause or perimenopausal transition. The time involved can range from one to 10 years. More than one third of the women in the United States, about 36 million, have been through menopause. With a life expectancy of 81 years, a 50-year-old woman can expect to live more than one third of her life after menopause. Low estrogen levels are linked to some uncomfortable symptoms in many women. The most common and easy to recognize symptom is hot flashes -- sudden intense waves of heat and sweating. Some women find that these hot flashes disrupt their sleep, and others report mood changes. Other symptoms may include irregular periods, vaginal or urinary tract infections, urinary incontinence (leakage of urine or inability to control urine flow), and inflammation of the vagina. Because of the changes in the urinary tract and vagina, some women may have discomfort or pain during sexual intercourse. Many women also notice changes in their skin, digestive tract, and hair during menopause. Because the menopausal years place unique nutritional demands on a woman’s body, Source Naturals created MENOPAUSEMULTIPLE. This comprehensive formula brings together optimal amounts of the finest phytonutrients and herbs--including genistein, black cohosh, and chaste berry--plus vitamins and minerals known to support the biochemistry of mature women.

    Bio-Aligned Formula™

    MENOPAUSE MULTIPLE is a comprehensive herbal-nutrient formula that supports the multiple, interconnected systems involved with female hormone function.

    Hormonal Regulation

    Hot flashes are related to hormone levels. As estrogen declines, FSH and LH (folliclestimulating and luteinizing hormones) increase, causing blood capillaries to dilate. This brings more blood and higher temperatures to the skin. Soy isoflavones and other herbs can mimic the effects of estrogen. Support for the adrenal glands is important since they account for most estrogen production after menopause.

    Musculoskeletal System

    During and after menopause, a woman’s hormonal balance and biochemistry change. Lower estrogen levels may affect bone density. Phytonutrients and calcium are important to maintain healthy bones in postmenopausal women. Calcium and magnesium work together in the metabolism of bone.

    Heart & Circulation

    Menopause increases concern for the health of the heart and circulatory system. Soy isoflavones and other ingredients may help maintain healthy cholesterol levels. To regulate homocysteine levels for cardiovascular health, vitamins B-6, B-12, and folic acid are critical.

    Liver Support

    Among its many functions, the liver has the important job of promoting hormonal balance by processing excess levels of hormones. The powerful antioxidant, N-acetyl cysteine, helps the liver detoxify chemicals and milk thistle is a liver protectant.

    Energy Generation

    The fatigue that is common during menopause makes nutritional support for energy and metabolism especially important. Metabolism can influence weight, energy levels, and mood. MENOPAUSE MULTIPLE contains ingredients that support energy generation, including the advanced nutrients CoQ10 and lipoic acid and ginkgo biloba.

    Antioxidants: Anti-Aging

    Antioxidants help protect the circulatory system, which is important as estrogen declines. Antioxidants also defend tissues and cell membranes in all your body systems from free radicals, which are formed during normal cellular metabolism. Some important antioxidants: vitamin E, vitamin C, selenium, zinc, and manganese all have strong antioxidant powers.

    Lifestyle Tips for a Healthy Transition

    Get Moving. Exercise is a powerful remedy for many menopause complaints and may help prevent future menopause-related diseases. It promotes better, more restorative sleep, and it stimulates production of endorphins, or “feel good” brain chemistry. Some women report having fewer hot flashes when they exercise regularly. Eat Well. A balanced diet low in saturated fat and high in whole grains, fruits and vegetables, with adequate water, vitamins and minerals contributes to good health. Women at perimenopause and beyond have special dietary concerns, because both heart disease and osteoporosis are greatly affected by diet. A balanced diet is also important for bone development and maintaining bone strength. Some women – especially those who are elderly and have reduced appetites, who diet frequently, who don’t consume diary products, or who have eating disorders – may not consume adequate vitamins and minerals to maintain optimal bone mass. There is evidence that the natural, estrogenlike compounds in soybeans and many other plant foods used in MENOPAUSE MULTIPLE may reduce hot flashes and vaginal dryness and increase bone density in women after menopause. Studies suggest that body cells respond to plant estrogens as if they were weaker versions of the human hormone. So consuming more of these estrogen-mimicking compounds may help compensate for the loss of estrogen naturally as women age. Prevent Bone Loss. Osteoporosis is one of the most preventable of bone diseases. Exercise maintains the strength of bones through aerobics, stair climbing, hiking, or walking. Prevention focuses on nutrition for bones, including a sufficient calcium intake of 1000 to 1500 mg/day.

    Musculoskeletal System: Black Cohosh, Dong Quai, Licorice, Soy Isoflavones, Boron, Calcium, Magnesium, Manganese, Vitamins A, B-6, B-12, C, D & E, Folic Acid

    Heart and Circulation: Black Cohosh, Coenzyme Q10, Dong Quai, Licorice, Soy Isoflavones, Magnesium, Vitamins B-6, B-12, & E, Folic Acid

    Hormonal Regulation: Black Cohosh, Dong Quai, Licorice, Soy Isoflavones, Vitex, Vitamins B-5 & C

    Liver Support: Coenzyme Q10, N-Acetyl Cysteine, Dandelion, alpha-Lipoic Acid, Silymarin, Selenium, Vitamin C, Biotin

    Antioxidant Defense: Coenzyme Q10, N-Acetyl Cysteine, alpha-Lipoic Acid, Silymarin, Selenium, Zinc, Vitamins A, C & E

    Energy Generation: alpha-Lipoic Acid, Coenzyme Q10, Magnesium, Manganese, Zinc, Vitamins B-1, B-2, B-5, & B-6, Niacinamide

    References
    Abraham, G.E. & Grewal, H.G. 1990. JRM, 35:503. Anderson, J.W., et al. 1995. The New England Journal of Medicine, 335(5): 276-82. Avioli, L. V. (1993). Calcium and Bone: Myths, Facts and Controversies in the Osteoporotic Syndrome: Detection, Prevention and Treatment, 3rd ed. (Avioli ed.) New York: Wiley-Liss. Christy, C.J. 1945. American Journal of Obstetrics & Gynecology, 50:45. Colborn, Theo. 1996. Our Stolen Future. New York: Dutton. Murkies, A.L., et al. 1995. Maturitas, 21:189-95. Nielsen, F.H., et al. 1987. FASEB J, 1:394-97. Raines, E.W., & Ross, R. 1995. Journal of Nutrition, 125:624S-30S. Tranquilli, A., et al. 1994. Gynecological Endocrinology, 8(1):55-8.



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