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The Unsettling Truth About Plastic: Microplastics Found in Human Stool Samples
July 29, 2023 11:04 AM
We all know that plastic pollution is a serious issue, but what we may not be aware of is that we are consuming it. Yes, you read that right. The researchers have recently discovered microplastic particles present in human stool samples, making us ingest the plastic we produced. It is not only our oceans and landfills that are clogged with plastic waste, but even our bodies, and that's alarming.
According to the study, participants from Finland, Italy, Japan, the Netherlands, Poland, Russia, the United Kingdom, and Austria were tested for ten different types of plastics, and nine types were found in their stool samples. On average, participants had 20 microplastic particles per 10 grams of stool. That's a concerning number.
As we all know, plastic is everywhere, from plastic bags to water bottles, from household items to toys, and the list goes on. A recent study revealed a frightening fact that our food, especially seafood and sea salt, and tap water and bottled water contain microplastics too. It is surprising to know that plastic is all around us, and we are consuming it daily.
Apart from being present in our bodies, research suggests that microplastics may have adverse effects on our gut microbiota. As per a study conducted by the University of Vienna, polystyrene microplastics adversely affected the gut barrier, microbiota, and metabolism of mice. Moreover, it can lead to a bacterial imbalance in our gut, decreasing our immune response.
Microplastics have a size smaller than 5 millimeters and are much smaller than the size we can see with naked eyes. Therefore, our bodies cannot filter them out. As a result, these microplastics can cause inflammation, obstruct our digestive system, and damage our gut lining.
The impact of plastic on the environment and marine life is alarming, but knowing that we, humans, are part of the problem is overwhelming. The amount of plastic waste we produce every year is immense, and if we don't change our ways, it will only get worse.
The Solution to Microplastics in Our Digestive Tract Could Be Psyllium Husk and Inulin.
Psyllium husk is a soluble fiber that is derived from the seeds of the Plantago ovata plant. It is a powerful colon cleanser that can rid our bodies of toxins, including microplastics. When mixed with water, psyllium husk forms a gel-like substance that bulks up and moves through our digestive tract, trapping and removing microplastics along the way. Psyllium husk is also known to help regulate bowel movements and reduce inflammation in our gut.
Another solution to microplastics in our digestive tract is prebiotics, specifically inulin. Inulin is a type of soluble fiber that feeds friendly bacteria in our gut, promoting gut health. Studies have shown that inulin can strengthen the gut lining, which can reduce the absorption of toxins like microplastics into our bodies. Inulin can also help regulate bowel movements and reduce inflammation in our gut.
In addition to psyllium husk and inulin, there are other steps we can take to reduce our exposure to microplastics. One such step is to avoid plastic packaging and utensils when possible and opt for reusable and sustainable options instead. We can also be mindful of the products we use that contain microplastics, such as cosmetics and cleaning products, and choose more natural alternatives.
It is also important to note that the effects of microplastics on our health are still being studied, and more research is needed to fully understand the extent of their impact. However, taking steps to reduce our exposure to microplastics and improve our gut health can only be beneficial for our overall well-being.
The discovery of microplastics in human stool samples is the harsh reality of the plastic pollution crisis. The studies strongly suggest that it may have severe implications for human health (we haven't even touched on the topic of endocrine disruptors due to plastics), and we must take action to reduce plastic consumption and pollution.
Reducing plastic waste from our daily lives might seem challenging, but it's essential if we want to create a healthier planet for ourselves and the generations to follow. Being more conscious of our daily habits in using plastic, choosing eco-friendly alternatives, and encouraging others to do the same can go a long way in reducing our plastic footprint.
We must work together as a community to reduce plastic waste and promote a sustainable future. The change starts with us, and together we can make a difference. You can get started to better health by adding psyllium husk and inulin to your daily supplement regiment. Your colon will thank you for it!
How To Heal Cold Sore Naturally!!
July 15, 2017 12:14 PM
A cold sore is a concern that most of us have dealt with at least one time in our life, and for some people, they are a recurring nightmare. No matter which category you fall into, natural healing of that cold sore is a realistic possibility. If you know how to naturally treat a cold sore you can get the fast and effective relief -efficiently delivered to your lips- no matter the time of the year.https://www.youtube.com/watch?v=L8hTEZJWMr4&rel=0
"Oral herpes is an infection caused by the herpes simplex virus, and it can be transmitted by kissing, hugs, and using same eating utensils."
Replace Steel With Copper Utensils At Home To Aid Weight Loss
December 19, 2016 10:59 AM
All your utensils in your kitchen may be steel, but new research shows it may be time to replace them with cooper. Cooper utensils provides a whole host of healthy benefits while maybe aiding in weight loss. New research shows that the more cooper present the easier it is for a body to break down fat.
"Copper also helps cleanse and detox your stomach."
How to detoxify from heavy metal aluminum toxitity
November 09, 2010 06:04 PM
Although aluminum is not a heavy metal, it can be toxic if present in excessive amounts or small amounts if it is deposited in the brain. Many of the symptoms of aluminum toxicity are similar to those of Alzheimer’s disease and osteoporosis. Aluminum toxicity can often lead to colic, rickets, gastrointestinal disturbances, poor calcium metabolism, extreme nervousness, anemia, headaches, decreased liver and kidney function, forgetfulness, speech disturbances, memory loss, softening of the bones, and weak, aching muscles. Since aluminum is excreted through the kidneys, toxic amounts of aluminum can often impair kidney function.
When aluminum salts accumulate in the brain, seizures and reduced mental function can often result. In order to reach the brain, aluminum must pass the blood-brain barrier, which is an elaborate structure that filters the blood before it reaches the vital organ. Although elemental aluminum does not ordinarily pass through this barrier, certain aluminum compounds, such as aluminum fluoride, will. Many municipal water supplies are treated with aluminum sulfate and fluoride. These two chemicals readily combine with each other in the blood and are poorly excreted in the urine. The absorption of high levels of aluminum and silicon in the intestines can result in the formation of compounds that accumulate in the cerebral cortex and prevent nerve impulses from being carried to and from the brain in the proper manner. This situation can be aggravated by a chronic calcium deficiency.
People who have spent their career in aluminum smelting plants for long periods have been known to experience dizziness, impaired coordination, and a loss of balance and energy. When aluminum accumulates in the brain, the above symptoms are often caused. Perhaps the most alarming thing to note it that there is evidence to suggest that long-term accumulation of aluminum in the brain may contribute to the development of Alzheimer’s disease. It has been estimated that an ordinary person ingests about 3 and 10 milligrams of aluminum a day. Aluminum, being the most abundant metallic element in the earth’s crust, is primarily absorbed in the body through the digestive tract, but can also be absorbed through the lungs and skin. Additionally, aluminum can be absorbed by and accumulate in the body tissues. Since aluminum permeates our air, water, and soil, it can be found naturally in varying amounts in almost all food and water. Aluminum is also used to make cookware, cooking utensils, and foil, along with being present in many other everyday products including over-the-counter painkillers, anti-inflammatories, douche preparations, antacids, baking powder, food processing, antiperspirants, toothpaste, dental amalgams, bleached flour, grated cheese, table salt, beer, and municipal water supplies.
The following nutrients are very helpful when dealing with aluminum toxicity: apple pectin, calcium, magnesium, coenzyme A, garlic, kelp, lecithin capsules or granules, l-glutathione, a multivitamin and mineral complex, SAMe, vitamin B complex, N-Acetyl Cysteine, and vitamin E. Additionally, the following herbs are great for blocking damage to the body from toxic heavy metals and radiation when taken regularly: burdock root, Echinacea, ginseng, ginkgo biloba, and fiber. Other recommendations to help prevent aluminum toxicity include maintaining a diet that is high in fiber and includes apple pectin; using only stainless steel, glass, or iron cookware, with stainless steel being the best; and being aware of the products that contain aluminum by reading labels and avoiding those that contain aluminum. Sulfur container foods like N-Acetyl Cysteine can help find up heavy metals and eliminate them from the body. If you suspect you have heavy metal toxicity, consult your health care provider immediately.
Clantro (Coriander Plant) to remove heavy metals
November 05, 2009 01:51 PM
Cilantro Heavy Metal Detox With Chlorella
Planetary Herbals is pleased to introduce Cilantro heavy metal detox, a unique herbal cleansing formula for defense against today’s environmental toxins. The herbs in Cilantro heavy metal detox are known to bind to heavy metals, helping to clear them from the body. Chlorella is added to increase the chelating and cleansing actions of cilantro. This combination also provides effective antioxidant support for overall cell health.
Planetary Herbals Cilantro heavy metal detox contains organic cilantro leaf and organic chlorella, for the purest product possible.
Herbs: Nature’s Answer to a Toxic World
Cilantro (one of the names used for the leaves of the coriander plant, Coriandrum sativum) is an ancient herb that has been used for millennia for health and for its robust, savory taste. Beyond its culinary value, modern research has confirmed the benefits of cilantro as a natural means of internal cleansing.
Recent studies show the cilantro attaches to heavy metals in the bloodstream. This process, known as “Chelation,” helps our bodies eliminate metals from our systems, and helps cleanse and purify our tissues, organs and blood. This process is supported with the addition of chlorella, single celled algae that work synergistically to enhance cilantro’s chelating and cleansing ability.
Binding heavy metals
Thousands of noxious chemical compounds, many of which didn’t exist on the planet 100 years ago, now pervade our food, water, and air. Heavy metals like lead, mercury, arsenic, aluminum, and cadmium enter our bodies through food, air, cooking utensils, deodorant, and even the fillings in our teeth.
Cilantro’s properties that enable binding with these toxins are thought to come from unique constituents, including citric acid, phytic acid, and electrolytes that attach to metals. The sequestration of metal ions by chlorella is assumed to be accomplished by surface ligands in the cell walls. Simply stated, both cilantro and chlorella contain properties that bind with metals, and chlorella additionally helps purge the bound metals from the organs.
Planetary Herbals: the PhytoDynamic Difference
Cilantro heavy metal detox is the latest in a herbal product line based on the principles of PhytoDynamics. PhytoDynamics unites a profound understanding of the interaction between plants and people, a commitment to holistic integrity of herbs for optimal efficacy, a strong grounding in scientific research, a world class quality control team, and a level of clinical expertise unmatched in the industry.
February 27, 2009 02:34 PM
Mumps, a common viral illness mostly occurring during childhood, is caused by a type of virus that is known as a paramyxovirus that infects the parotid glands, which are the salivary glands that are located at the jaw angles below the ears. Symptoms include swelling of one or both glands plus headache, fever, chills, decreased appetite, sore throat, and pain when swallowing or chewing, especially when swallowing acidic substances such as citrus juices. A lot of times, one of the parotid glands will swell before the other, and as swelling in one gland subsides, the other begins to swell. Mumps travels from person to person by means of infected droplets of saliva or direct contact with contaminated materials. This illness can be contracted through sneezing, coughing, kissing, talking, breathing, drinking out of the same glass as an infected person, and sharing utensils. This virus has an incubation period that can vary from fourteen to twenty-four days, with the average period being about eighteen days. A person with mumps is contagious any time from forty-eight hours before the onset of symptoms to six days after the symptoms have started. Although this attack is not as contagious as measles or chickenpox, it is similar in that one attack usually gives lifetime immunity.
Mumps occurs most commonly in those children that range between the ages of three and ten. However, it can occur through teenage years and, rarely, in adulthood. If this illness does occur after puberty, the ovaries or testes may become involved and sterility may result. If the testicles are affected, they become swollen and painful, while abdominal pain will result if the ovaries or pancreas is affected. Other organs that can be affected by mumps in rare or severe cases include the brain, pancreas, and kidneys. All of these can potentially cause serious complications.
The following bacteria are beneficial in dealing with mumps. Unless otherwise specified, the dosages given are for adults. For children between the ages of twelve and seventeen, the dose should be reduced to three-quarters of the recommended amount. For children between six and twelve, one-half of the recommended doses should be used, while one-quarter of the amount should be used for children under the age of six. Bifidobacterium bifidus should be taken as directed on the label to provide friendly bacteria, which contains antibiotic substances that inhibit pathogenic organisms. Vitamin C with bioflavonoids helps to destroy the virus and eliminate toxins if taken in dosages of 500 mg every 2 hours until improvement is noted.
One 15 mg zinc lozenge should be taken every 4 to 6 hours to aid healing. Acidophilus should be taken as directed on the label, as it contains antibiotic substances that inhibit pathogenic organisms. A free-form amino acid complex should be taken as directed on the label, as it is important for tissue repair and healing. 50,000 IU of vitamin A with mixed carotenoids should be taken daily, as it potentates immune function. Kelp, which contains essential minerals, iodine, and vitamins, should be taken in dosages of 1,000-1,500 mg daily. Additionally, the following herbs are beneficial in dealing with mumps: catnip, chamomile, dandelion, Echinacea, elderflower, lobelia, mullein, peppermint tea, slippery elm bark, barley, and yarrow.
Vitamin supplements are great to help fight off colds, but with the mumps always consult your doctor, if left untreated further life threatening complications may occur which is not desirable by anybody. Vitamin and Herbs are available at your local or internet health food store.
February 23, 2009 11:54 AM
Mononucleosis is an infectious viral disease that is most often caused by the Epstein-Barr virus. More rarely, it can be caused by cytomegalovirus. Both of these viruses are members of the herpes family. Once the virus enters the body, it multiplies in lymphocytes. Mono then affects the respiratory system, the lymphatic tissues, and glands in the neck, groin, armpits, bronchial tubes, spleen, and liver.
Symptoms of mono include depression, extreme fatigue, fever, generalized aching, headache, jaundice, and loss of appetite, sore throat, pain on the upper left side of the abdomen, puffy eyelids, swollen glands, and sometimes, a bumpy, red rash. Additionally, the spleen may become enlarged and liver function may be affected. Meningitis, encephalitis, and rupturing of the spleen are very rare complications that may develop as a result of mono.
The virus’s associated with mono are extremely contagious, often being transmitted from person to person by close contact such as kissing, which explains why mono is often referred to as the “kissing disease.” The disease can also be spread by sharing food or utensils, as well as through sexual contact or through respiratory droplets. The incubation period for mono is about ten days in children and thirty to fifty days in adults. A lot of mononucleosis cases occur in the military and in colleges, as living conditions are crowded and sleeping patterns are inadequate. High school students also have a high incidence of this disease. Mono is most common among children and adolescents, as about 90 percent of people over age thirty-five have mono antibodies in their blood, which means that they had the disease at some point in their lives, although many do not even know they had it.
The symptoms of mononucleosis are very similar to those of influenza, which often results in mono often being mistaken for it. However, with mono, the symptoms tend to be more persistent, with acute symptoms usually lasting from two to four weeks, and fatigue persisting for three to eight weeks after the other symptoms disappear. The disease can even linger for a year or more in some individuals. It can also produce recurring, but successively milder, attacks. If the immune system has been compromised by an organ transplant, HIV/AIDS, or other viruses, the mono symptoms can be extremely serious and chronic.
Mononucleosis is diagnosed through a blood test called a spot test. This test reveals the presence of specific viral antibodies and also confirms the presence of mono. Additionally, a liver function test can assist in the diagnosis.
The following nutrients are considered to be extremely important in dealing with mononucleosis: acidophilus, proteolytic enzymes, vitamin A with mixed carotenoids, and vitamin C with bioflavonoids. Other nutrients that have proven to be both important and helpful include: DMG, a free-form amino acid complex, garlic, vitamin B complex, zinc lozenges, maitake extract, reishi extract, shiitake extract, a multivitamin and mineral complex, and raw thymus glandular.
Astragalus and Echinacea are also beneficial in boosting the immune system, while cat’s claw has immune-enhancing properties that act against viral infections. Dandelion and milk thistle are beneficial in protecting the liver. Goldenseal helps to fight infection, while olive leaf extract helps to inhibit the growth of viruses that cause mono. Pau d’arco balances the bacteria in the colon and spirulina contains phytonutrients that are helpful in boosting the immune system.
Whether you want to combat mono symptoms naturally or use prescription drugs, always consult your family physician before taking matters into your own hands. A correct diagnosis is important to how one might want to combat sickness in general. Natural vitamins like the ones listed above are available at your internet health food store.
*Statements contained herein have not been evaluated by the Food and Drug Administration. Vitamins and herbs are not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.
May 15, 2008 01:21 PM
Copper is an essential trace mineral necessary for life, and it is necessary for the proper function of certain enzymes that allow certain biochemical functions of the body to take place. Without copper neither plant nor animal life would be possible.
Dietary sources include nuts, grains, seeds, beans and other vegetable protein sources. Although it is also obtained from animal sources, these tend to be rich in zinc, and for reasons that will be discussed shortly, the presence of zinc can deplete copper absorption. Other common sources are copper cooking utensils and drinking water from copper pipes. After digestion, copper is absorbed into the body through the stomach and the small intestine. It is also possible for copper to be absorbed through the skin from copper bracelets.
Once absorbed, copper is bound to albumin and taken by the blood to the liver, where it is bound to a plasma protein known as ceruloplasmin. Among the enzymes with which copper is associated as a ‘helper’ are Cytochrome C oxidase, used in the conversion of glucose to energy, Dopamine hydroxylase, an essential component in the biochemical production of adrenaline, and superoxidase dismutase, that protects against the oxidative damage of cell tissue. Of particular benefit are its anti-inflammatory and antioxidant properties, and its role in energy production. Because of its antioxidant effect, copper could well play a very important role in protecting against atherosclerosis, and cardiovascular disease, the ravaging effects of free radicals on body cells and also certain forms of cancer.
Copper is also important in electron transport, and is responsible for the blue coloration of the blood of most molluscs and many arthropods. This is because rather than hemoglobin, these animals use the copper-based hemocyanin for oxygen transport in the blood. Rather than the iron-containing hemoglobin making the blood of these creatures red as it is with mammals, theirs is blue due to the hemocyanin. Copper salts are generally green and blue, as are the blue copper proteins plastocyanin and azurin.
So how is copper used by the body? It is, after all, fairly toxic, as little as 30 grams being fatal to humans, bringing on similar symptoms to those of arsenic poisoning. It is in fact the reason for its toxicity that also renders it so useful to the body. The toxicity is largely due to the ability of copper to accept and donate electrons as it changes between oxidation states. This results in the generation of very reactive radicals that can cause severe oxidative stress. The complete reason for its toxicity has yet to be determined, but the stress caused to body cells by free radical oxidation is a very serious condition.
It is this rapid change in its oxidation state that is valuable to the enzymes with which it is associated. The ceruloplasmin is responsible for most of the transport of bivalent copper around the body, in the tissues of which it helps to form the bivalent copper enzymes previously mentioned, such as Cytochrome C oxidase and Lysyl oxidase. In doing so the copper is converted to the monovalent state.
It also helps to aid in the production of the strong antioxidant Superoxide dismutase (SOD). What this enzyme does is to catalyze the formation of oxygen and hydrogen peroxide by the dismutation of superoxide, a negative ion consisting of two oxygen atoms and a free electron, and hence a very powerful free radical. Dismutation is the simultaneous oxidation and reduction of the species, rendering the free radical relatively harmless. This type of action on free radicals is a very powerful one, and essential in the body’s fight against such free radical species that are so dangerous to animal cells.
SOD exists in more than one form, and can also contain zinc, manganese and nickel in addition to copper. The internal fluid (cytosol) of practically all eukaryotic cells (cells containing a nucleus) contain a form of Superoxide dismutase dependent on copper and zinc, while most mitochondria contain an SOD with manganese.
Another of the important uses that your body can find for copper lies in the production of hemoglobin. This is because copper is needed for the storage and release of iron to produce hemoglobin, the protein in red blood cells. It is believed that ceruloplasmin is involved in the catalytic formation of ferric iron by the oxidation of ferrous iron, so allowing the iron to be attached to a protein that transfers it round the body to enable its use in the biosynthesis of various ferrous compounds, especially of hemoglobin.
Copper bracelets are commonly worn by arthritis sufferers, and there is a scientific explanation for that. As previously inferred, it is believed to be possible to absorb copper through the skin and copper is known to be involved in the formation of collagen and is a commonly used treatment for arthritis and osteoporosis. Part of its effect on arthritis is likely due to the antioxidant effect of the SOD that helps to reduce the inflammation at arthritis sites.
Although a deficiency in copper can lead to serious health problems, an excess is also harmful. Potential conditions include neurological problems, liver damage and bone abnormalities, although deficiency is far more common because of the competition between copper and zinc. Zinc is a copper antagonist, as is iron and manganese, and copper imbalances can be moderated by the use of these as supplements.
The symptoms of a copper deficiency include fatigue, hair loss, stunted growth, anorexia and a host of other conditions. Luckily, however, a deficiency is rare and most people receive a sufficient amount of copper in their diet. Supplements are available to ensure an adequate intake.
There is still much to be learned about the interaction between copper and enzymes, and there is also a great deal still to be learned of its role in human metabolism and biochemistry than is currently known. However, sufficient is known already for us to be certain that copper is a very important trace element and that we should be certain that our intake is sufficient, given that zinc iron and manganese compete to prevent copper being absorbed by the body.
Neurological Health and CoQ10
February 25, 2007 12:06 PM
Between 1946 and 1965, 78 million Americans were born, creating the largest number of children in U.S. history. This Baby Boom generation has greatly influenced the makeup of American society and undoubtedly w ill continue to do so. Thanks to good nutrition and health care, Baby Boomers are aging well and have an excellent life expectancy. For the first time in history, we have more people turning 60 every day, and record numbers of adults reaching their seventh decade. As a result, neurological diseases associated with aging, such as Parkinson’s disease, are becoming major health care concerns. The good news is CoQ10 has applications for neurological diseases, in addition to its better known use for cardiovascular diseases.
Q. What is CoQ10?
A. CoQ10 is a natural, fat-soluble nutrient present in virtually all cells. CoQ10 also is known as ubiquinone (existing everywhere there is human life). CoQ10 is vital to the production of adenosine triphosphate (ATP). ATP is the energy-rich compound used for all energy-requiring processes in the body.
Q. Isn’t CoQ10 a supplement for heart health?
A. Yes, it is. Because the heart requires lots of ATP to meet its high energy needs, CoQ10’s function in heart health is well understood. Numerous clinical studies have demonstrated that when individuals with heart disease take CoQ10, their symptoms improve, sometimes quite dramatically. Supplemental CoQ10 improves the heart’s pumping ability, improves blood circulation, increases tolerance to exercise, and improves the heart’s muscle tone. CoQ10 also is a powerful antioxidant and protects heart tissue from free-radical damage.
Q. How does CoQ10 affect brain health?
A. CoQ10 works in the brain the same way it works elsewhere in the body: it’s essential to ATP production. Nearly all human cells contain tiny structures called mitochondria. Mitochondria are referred to as cell powerhouses because they produce cellular energy. Depending on what each cell’s job is. There can be several thousand mitochondria in one cell. If a cell needs a lot of energy, it will have more mitochondria. This explains why heart cells contain so many mitochondria; the continual pumping of blood requires continual ATP production.
The brain also requires huge amounts of uninterrupted energy to regulate, integrate, and coordinate ongoing nervous system transmissions. To meet this need, ATP production within the mitochondria of brain cells is vital. Since CoQ10 exerts such a powerful influence on heart cells in ATP production, it was a natural progression for scientists to wonder how it affects brain cells. Brain and nervous system research led to the conclusion that the same intracellular principles apply. CoQ10 is produced in the body to assist in ATP production. Without it, ATP cannot be produced.
The most important discovery regarding CoQ10 and the brain is that CoQ10, when formulated with certain ingredients, can cross the blood-brain barrier and enter the brain’s mitochondria. If large amounts of CoQ10 can get into the brain cell’s mitochondria, its ability to make ATP is greatly enhanced.
Q. What is the blood-brain barrier and why is it important?
A. The blood-brain barrier is a unique anatomical structure. The cells that make up the blood vessels that provide blood to the brain are extremely close together. This greatly restricts what can leave the bloodstream and enter the brain. While the blood-brain barrier protects the brain and spinal cord from potentially toxic substances, it also can be a significant obstacle to therapy of central nervous system disorders. Only substances with certain solubilities or those that have a transport system can cross the blood-brain barrier to a significant degree.
Obtaining optimal absorption of CoQ10 is difficult. The CoQ10 molecule is large and inflexible. The easiest and least expensive way to increase absorption levels is with the use of harsh solvents such as propylene glycol. However, at higher doses, these types of chemicals are considered dangerous (neurotoxic) to the person with a serious neurodegenerative disease. It is more difficult, as well as more expensive (considering raw materials, research, and proper manufacturing methods) to promote absorption with less harmful alternatives. However, reputable companies ensure that their products are safe for all their customers. Look for CoQ10 products formulated with vitamin E and other safe ingredients such as Micosolle.
Nearly all CoQ10 supplements enter the bloodstream. But, only CoQ10 supplements with special formulations have been scientifically shown to enter the mitochondria and cross the blood-brain barrier.
Q. If CoQ10 is made in the body, why take supplements?
A. While CoQ10 is synthesized in the body, these levels may be insufficient to meet the body’s requirements. Researchers have discovered CoQ10 levels diminish with age and as a result of dietary inadequacies and various disease states. They also have determined some medications significantly reduce CoQ10 levels in the body.
Although CoQ10 exists in some dietary sources, it may not be realistic to obtain CoQ10 through food alone. For example, it would take approximately 3 pounds of sardines, 7 pounds of beef, or 8 pounds of peanuts to equal 100 mg of supplemental CoQ10.
Q. How does CoQ10 help people with Parkinson’s disease?
A. CoQ10 seems to have several beneficial actions in the illness. Researchers have looked at mitochondria in brain cells and determined people with Parkinson’s disease have reduced activity of Complex I in the electron transport chain. Recent research has proposed the reduced activity of Complex I interferes with the brain-signaling chemical dopamine. Stored and newly synthesized dopamine is depleted. The dopamine depletion causes nerve cell degeneration.
A recent clinical study involved 80 patients with Parkinson’s disease (both men and women). The researchers first evaluated all the participants to establish scores for basic motor skills (measuring the ability to control physical movements such as walking), mental status (whether the person was depressed or experiencing memory loss) and the activities of daily living (whether the person was experiencing difficulty with handwriting, dressing themselves, using utensils such as knives and forks, and so on). This scale is known as the Unified Parkinson’s Disease Rating Scale (UPDRS). This process is known as establishing “baseline values,” that is, the condition of the patient before receiving any treatment.
Participants were divided into 4 groups. Each group received either 300 mg, 600 mg, or 1200 mg of the special form of CoQ10, or a placebo. The researchers observed the participants for 16 months.
The results of the study showed that all the participants who received CoQ10 had smaller declines in function compared to the placebo group, but the smallest decline was experienced by the group taking the highest amount of the special form of CoQ10.
The most significant results were noted specifically in the activities of daily living scores by the people taking 1200 mg of CoQ10 daily. These people retained better ability to feed and dress themselves, speak, walk, and bathe or shower by themselves. They maintained greater independence for a longer time. Parkinson’s disease, as with other neurodegenerative diseases, robs the sufferer of their ability to control the movements of their own body and care for themselves. Supplementation with CoQ10, while not a cure, is the first intervention that showed a slowing in the progressive deterioration of the function associated with this disease.
Q. What were the results of clinical research on Huntington’s Disease?
A. A randomized, double-blind, placebo controlled study respected type of study, was conducted at the University of Rochester. All of the 347 Huntington’s disease (HD) patients were experiencing some HD symptoms, but were still in the early stages of the disease. The patients (who did not know which drug they were receiving) were randomly assigned to four different treatment groups: 25 percent received Remacemide, 25 percent received CoQ10, 25 percent received both, and 25 percent received a placebo, or sugar pill. The researchers, who also did not know which patients got which drug, watched and recorded their progress for two and one-half years. Remacemide is a new drug made by Astra Seneca that blocks the neurotransmitter glutamate in the brain, that has long been suspected of contributing to the death of brain cells in Huntington’s disease.
Unfortunately, in the CARE-HD study, Remacemide had no effect on the progression of the disease in patients in the early stages. However, the individuals who received 600 mg of CoQ10 per day experienced some slowing of the disease progression. They were able to manage daily activities, such as meal preparation, housekeeping tasks, and personal care longer than those not on CoQ10. They were also able to focus their attention better and were less depressed and irritable. The portion of the studied patients receiving 600 mg of CoQ10 per day experienced a 15 percent decline in the progression of HD. According to the researchers conducting the study, a 15 percent decline in the progression of HD would roughly translate into approximately one more year of independence for patients. This is the very first study from more than a dozen Huntington’s disease patient trails that showed any modification of the course of the illness.
Of note, the effects of the CoQ10 had not abated at the end of the research study. That is, the benefit of using CoQ10, 600 mg per day, was still increasing; this suggests that the longer a patient supplements with CoQ10, the greater the decline in the progression of HD. The next phase of the CARE-HD research will test a higher dose of CoQ10 (1200 mg or more per day), with more patients (over 1000), for a longer period of time (approximately 5 years). This study should improve our understanding of the optimal dose and the total achievable decline in the progression of HD. The CoQ10 product used in the CARE-HD study was designated an Orphan Drug by the FDA. The product utilizes a proprietary, patent-pending delivery mechanism, which is proven to be safe and tolerable at high doses for people suffering from neurodegenerative diseases, substantially improving brain tissue levels of CoQ10.
Q. What other diseases could benefit from CoQ10 supplementation?
A. Studies show CoQ10 levels are greatly reduced in Alzheimer’s patients. Mitochondrial abnormalities also are noted; however, research has yet to determine how or why this occurs. Some scientists believe damage to mitochondria is an early feature of the disease. Free-radical damage also is a feature of Alzheimer’s.
In a study of 27 Alzheimer’s patients, subjects were given 60 mg of CoQ10, 150 mg of iron, and 180 mg of vitamin B6 daily. Each patient’s mitochondria activity was effectively activated. All patients continued to experience gradual decline. However, researchers believed that with this combination, the progression was much slower and allowed the patients to experience 1 to 2 years of extended good health.
ALS (also known as Lou Gehrig’s disease) is a progressive, fatal, neurological disease. It occurs when the nerve cells in the brain that control voluntary movement gradually degenerate. Investigation of CoQ10 in individuals with ALS is just beginning. Researchers at the Eleanor and Lou Gehrig ALS Center at Columbia University recently conducted a small clinical pilot trial of CoQ10 in ALS. The study was an open label study, which meant that everyone enrolled received CoQ10, 400 mg three times per day. Of the 16 patients originally enrolled, nine patients completed the study. Six of these nine patients experienced some benefits. The patients declined from 0 – 25 percent in functional scores, 6 percent in strength, and 10 percent in breathing ability. These scores reflect a positive trend compared to the 50 percent decline that is seen in the natural history of ALS over the same period of time (5 to 9 months). Citing the need to conduct more studies of the effectiveness of CoQ10 for people with ALS is rapidly and efficiently as possible to get answers to patients and clinicians, another clinical trial is currently underway at the Gehrig ALS Center. This is a pilot study to determine if CoQ10 has short-term effects on motor nerves in the brain using magnetic resonance spectroscopy (MRS). The researchers are going to try to “see” if CoQ10 can change the chemical sin the brain’s upper motor nerves of people with ALS, an important next step of the investigation.
Q. Can taking CoQ10 prevent neurodegenerative disease?
A. To date, there have been no studies or research examining whether CoQ10 can prevent these diseases.
Alzheimer’s disease prevention is being clinically investigated. Researchers have determined that people who take certain anti-inflammatory medications seem less likely to develop the illness. A large, multi-centered trial is studying this connection.
Q. How much CoQ10 should I take?
A. Depending on your family history of neurological disease and your disease experience, studies show benefits at doses of 100 to 200 mg of CoQ10 daily. Some studies used doses of up to 1,200 mg per day.
CoQ10’s safety has been evaluated. To date, no toxicities have been reported. Mild stomach upset may occur. Taking CoQ10 with meals usually alleviates this rare effect.
Q. What should I look for in a CoQ10 supplement?
A. Use products which have a strong clinical research track record, supported by product-specific research from reputable institutions, and have been proven to be safe, tolerable and effective in treatment of neurodegenerative diseases. The CoQ10 product you choose should be proven to: be absorbed, enter the blood stream, cross the blood brain barrier and increase mitochondrial levels of CoQ10. If the product you are considering does not have evidence to support these points, keep looking. Once you have found a candidate, examine the product’s safety and efficacy record for neurodegenerative diseases- if the product has not been proven to be safe and effective, keep looking. Good products exist; however, caveat emptor.
CoQ10 supplementation for people with neurodegenerative diseases is supported by contemporary clinical research. CoQ10 is certainly not the only answer to the complex issues of management and treatment of these types of diseases. However, research indicates that it is a bigger piece of the puzzle than physicians and scientists ever imagined. As we continue to study this naturally occurring compound, we are finding more and more benefits to the body.
All CoQ10 is not created equal. For safety and overall effectiveness, use a CoQ10 product that is supported by product-specific research from reputable institution, which is proven to be safe, tolerable and effective at high doses; deviating from this set of criteria may do more harm than good for people with these serious illnesses. Choose clinically tested products from a well-respected company and increase the potential to achieve and maintain brain and neurological health.
Cuddlin’ in the Kitchen
July 27, 2005 03:44 PM
Cuddlin’ in the Kitchen
You and your sweetie can turn up the heat by cooking together.
Since the beginning of time, the pleasures of the table have been intertwined with those of the boudoir. (Remember the scene in the film Tom Jomes in which Tom and his amorata-of-the-moment wolf down a meal while staring lustily into each other’s eyes?) But when most of your kitchen time is spent trying to get everyone fed and out of the house in time for the night’s soccer game/ PTA meeting/ballet lesson, it can be tough keeping the pilot light lit on your love.
That’s why one of the best ways to spice up your sex life is to prepare a sensuous meal together sans offspring (thank heavens for doting grandparents with spare rooms!). A little fourhanded cooking- preferably while sharing some suggestive banter- can create chemistry that allows your playful, non-parenting side s to emerge, enhancing intimacy and setting the stage for the seductive feast to follow.
Just as the frenzied pace of modern living can often foster a sense of separation, cooking together as a couple can promote a sense of union. “Eventually you get a feel for your partner’s rhythms and adjust yours accordingly,” says food TV personality Jacqui Malouf, author of Booty Food (Bloomsbury). “Before you know it you’re passing the coriander, peeling the potatoes and stirring the risotto at precisely the right moments.”
With time, you can learn what each of you does best: Who has a flair for combining spices in just the right proportions? Who can chop carrots into perfect little matchsticks without taking all night? Since nothing kills the mood more than arguing over who misplaced the baker’s chocolate or the pasta platter, buy your ingredients earlier in the day and have all the necessary utensils out and at the ready. (Safety note: while two in a tiny kitchen can be steamily cozy, do be careful with hot pots and sharp knives.)
Four hands can also be better than two, so why not make the most of it? Malouf suggests approaching your combined efforts with a sense of adventure: “Use more than three ingredients in a salad dressing! Be daring with your desserts! Try concocting something with squab or squid or quince or quail- the sky’s the limit.”
One advantage of using exotic ingredients (or at least foods not normally found on your weekly shopping list) is that they can help you and your partner break through the limits of everyday experience by reawakening long-dormant senses. Go ahead- run your fingertips over the rough rind of a pomegranate before feeling the smooth, full seeds within. Inhale the sweet, perfumed scent of a dead-ripe apricot, and appreciate its downy skin. Admire the cool green beauty of a cut avocado, and share a spoonful with your sweetie.
Avocado, in fact, is one of the foods known for inflaming passion based on its suggestive shape, along with artichoke and asparagus- and that’s just the AS! (Chocoholics rejoice: Chocolate, full of the same feel-good chemical released by the brain when one falls in love, also makes the ecstasy encouraging grade, even when obtained in standard shapes.) “coincidentally, many foods long considered aphrodisiacs are low in fat (avocado and chocolate are delectably healthy exceptions) and are high in vitamins and minerals,” write Martha Hopkins and Randall Lockridge in Intercourses: An Aphrodisiac Cookbook (Terrace Publishing). “A diet heavy in these foods, then, yields a healthy blood healthy body with the energy, blood flow and nutrients needed for a peak sexual experience.” (The way these foods feed the imagination- the ultimate smorgasbord of pleasure- is a bountiful bonus.) Other foods, such as honey, have been treasured for supplying the energy needed to fan love’s flames far into the night; no wonder the sweet, sticky stuff shows up in a number of naughty-night concoctions.
Just as Venus, the Roman goddess of love, emerged fully formed from the sea, so do the foods that best encourage those under her spell. In addition to being chockfull of healthy protein, “seafood is elegant, clean and light enough to keep your sleek loving machine fully fueled but never weighed down,” says Jacqui Malouf. Oysters are famous- or infamous- for their amorous effects (Cassanova was fond of them) but aren’t for everyone; other romantic dining favorites include shrimp or scallops.
Time to Eat
Once you’ve worked your kitchen magic together, it’s time to move the action into the dining room. Again, a little preparation can keep the evening at a slow, sensuous boil. Use the best china you have, along with matching silverware, cloth napkins and nice glasses (sippy cups don’t count). The warm glow of candlelight can both set off your tantalizing table and set your hearts aflame, along with a rose or two in the most decorative vase you own. Music (from Mozart to Motown, depending on your taste) is another surefire mojo mover. But please guys- catch up with CNN or ESPN some other time.
When you do finally sit down to dinner don’t rush, even (especially) if fast-forward eating is the norm in your house. “Treat the food as if you are making love for the first time,” advises Kerry McCloskey in The Ultimate Sex Diet (True Courage Press). “Before putting any in your mouth, inhale its aroma to get your digestive juices flowing…Cut your food into small, bite-sized pieces, (which) will ensure that you enjoy each bite.” The idea is to enhance all of your senses, which will come in handy later on in the evening.
You can make your couple dining experience even more intimate by feeding each other; some foods. Like asparagus spears and shrimp, beg for finger-feeding. McCloskey recommends also trying chopsticks: “Because it will take longer to maneuver your food when using them, you will feel full sooner with less food.” That’s important since you don’t want to overeat- passing out right after dessert is not the way to impress your partner (they’ve seen you snoring away on the couch a hundred times before).
In the wee hours, happily exhausted, you can ponder this: No matter how hectic your lives get, you should always make time for each other. You already share a mortgage and kids. Cooking together is a great way to share sensuality, too.