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colostral can help boost immunity Darrell Miller 12/17/13
Acne Treatment of Different Skin Types Darrell Miller 9/20/11
Colostrum and immunity Darrell Miller 6/17/09
First, the Painful Inflammation Darrell Miller 4/3/08
A Periwinkle Extract Vinpocetine May Promote Cerebral Blood Flow Darrell Miller 12/1/07
Butterbur Extract Fact Sheet Darrell Miller 12/8/05




colostral can help boost immunity
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Date: December 17, 2013 12:14 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: colostral can help boost immunity

milkWhat is Colustrum

Colostrum is the milk produced by mammary glands in female mammals at the late stages of pregnancy and shortly after birth. It is yellowish in color and sticky. It has all the nutrients necessary to keep your child healthy and strong. Above all, it contains antibodies and living cells capable of protecting your child from infections. It is a key source of immunity. It is less in volume but highly concentrated with nutrients and antibodies. It has a laxative effect hence helps the child in the excretion process and elimination of bilirubin.

Colustrum Benefits

A newly born child should be breast fed at least 8 to 12 times a day. This enables the child to rip the maximum out of the colostrums in the milk. It contains secretory immunoglobulin that protects the mucus membrane of the infant. The membrane in the throat, intestines and the throat is fragile and needs such protection. The leucocytes in the colostrums is responsible for shielding the new born from viruses and bacteria. Colostrums contain beneficial bacteria. These bacteria are ingested in the digest tract boosting the intestinal activities.

Bovine colostrums developers depended upon this knowledge.

The Agrifood Research Finland established that bovine could help boost your immunity. They established that the colostrums could not cure an ailment but can prevent infection in a healthy rat. It also promoted the removal of coli bacteria in the bloodstream of a Calve. The study established that the bovine colostrums could control gastrointestinal diseases.

It takes about two weeks after birth for colostrum to mature into milk. The volume of antibodies in the milk drastically goes down and the milk volume increases. The immunity component in the milk does not varnish either. The milk is still capable to supply the child with immunological protection. What changes is the degree of protection. Remember as the child grows, he/she builds an independent immune system. The colostrums taken at early stages stimulates the process.

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Acne Treatment of Different Skin Types
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Date: September 20, 2011 11:30 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Acne Treatment of Different Skin Types

Not everyone has the same skin type, and if you have acne, then the treatment could be dependent on your skin type. Before discussing the different acne treatments available, therefore, it will be necessary to discuss the various skin types.

Skin types are graded in a number of ways, anything from 3 types to several. Here we shall discuss more than the normal three (oily, dry and normal) but instead look at seven.

1. Normal Skin

Normal skin looks evenly colored and textured, firm and smooth without larger pores. People with normal skin probably had mild acne when at high school, but cleared up fairly quickly during the teenage years without specialized treatment or scarring. Acne in this type of skin normally requires only mild topical treatment and a mild antibiotic face wash to keep the pores clean of dead skin cells.

Treatments designed to reduce sebum production could result in dry skin susceptible to environmental damage. What must be kept in mind is that the prime cause of acne is excessive production of skin oil, correctly known as sebum, becoming mixed with shed skin cells within the sebaceous pores and plugging them. When this plug gets infected with bacteria, the immune system leaps into action to produce puss through leucocytes attacking the bacteria, and inflammation designed to create temperature conditions alien to bacteria.

If you use treatments formulated to reduce sebum production in oily skin, then you might lose the natural skin oil needed to keep your skin waterproof and resistant to the pollution and chemical agents that can cause dermatitis.

2. Dry Skin

If you got through adolescence with few or no skin problems, and you have dry hair and your skin feels dry after washing, then you have dry skin. It is even more important with dry skin that you do not use sebum-reducing treatments, if you even get acne at all. Only the mildest acne treatments should be used if you have dry skin, thought is unlikely that you will get anything other the very mildest case if you really have dry skin.

Your skin can dry through age, so to be of a dry skin type, you should have suffered, or be suffering, these problems while you are 35 years old or under. After that age your skin tends to dry out naturally.

3. Oily Skin

This completes the trilogy of the classic skin types. Oily skin is associated with acne, and if your hair is oily, you tend to tan very easily rather than go red in the sun, and if oily make-ups, such as some foundations, tend to last only a short time, then you likely have oily skin.

You will also have suffered from acne as a teenager, and your skin will have a particular 'look'. It will often appear shiny, and will also seem to have a coarse texture with larger pores than most others seem to have. You will tend to get a lot of blackheads, not only as a teenager.

Oily skin is classically associated with acne, and it is for those with that skin type that classic treatments will be prescribed, such as antibiotics and Accutane.

Apart from these three skin types, there are others that have been defined involving a combination of these and also age.

Sensitive Skin

Sensitive skin is associated with broken blood vessels beneath the surface of the skin, and such skin types should be treated very carefully. If creams or lotions are applied to sensitive skin they should be rubbed in very gently as it could cause bruising.

Sensitive skin is no more susceptible to acne than most other skin types although significantly less so than oily skin. For that reason, treatments for sensitive skin should be similar to that for dry skin or in most cases normal skin.

Combination skin

Combination skin has an oily zone across the forehead, and down the nose and chin, the other areas of the face being normal or dry. Such skin can also be oily along the jaw line and normal to dry everywhere else. In such cases aggressive acne treatment might be necessary in the oily zones, and more mild treatments used in the areas which are normal.

There are three other classes or skin type based upon age or condition, one being mature skin and other ailing skin and the final type, surprise, surprise, being known as acne skin. Ailing skin is caused by skin conditions other than acne, and you should get the advice of a dermatologist if you believe you have this type of skin. Mature skin on the other hand is natural and occurs with age: the skin becomes slack and loose due to a slowing down of cell growth which causes the skin to lose elasticity. There is no cure for this type of skin other than cosmetic surgery, and it is rarely affected by acne.

Acne Skin

Acne skin is normally oily and associated with blackheads, pimples and spots. It is not normally applied to serious acne conditions, being mostly associated with skin which is generally 'spotty', as opposed to mostly clear. It is debatable whether acne skin is any different from oily skin which also tends to be covered with spots and pimples, and the treatments for acne skin are no different to those for oily skin: these are Accutane, antibiotics and topical treatments such as face washes and scrubs.

If you have acne skin you must be careful about the type of cosmetics and face cleansers you use, since either could aggravate your condition. This is not restricted only to those with oily skins of course, since everyone should be aware of the effect of cosmetics and face cleansers on their skin but it is more significant with those who suffer from acne. Cosmetics cannot cause acne, but they can help to aggravate infections which have already occurred.

Although most focus is placed on those with oily skins which are more susceptible to acne, people with any type of skin should consider carefully the types of cosmetic and cleansers which they use. Contrary to what you may have heard or read, acne has nothing to do with your diet - eating fatty foods or chocolates do not cause acne, which is caused only through production of excess sebum, or skin oil, by the sebaceous glands.

Irrespective of your skin type your physician will determine the best treatment that is appropriate for your particular case of acne. This may be different for individuals and may or may not change according to skin type. Antiseptic face washes or scrubs may be appropriate for some acne cases, Accutane might be the best treatment for others, while a course of internal antibiotics such as tetracyclines may be deemed appropriate for yet other cases.

Treating acne has three distinct phases:

1. Removal of the blackheads and lesions. The removal of lesions can also involve a degree of scar removal, although that is another topic. Black heads, whiteheads and other papules can be treated by the use of facial cleansers and scrubs. They should not be squeezed since the puss inside them could be forced deeper into the skin and so lead to a more generalized infection.

2. Treatment of the bacterial infection. The typical symptoms of acne, the papules, whiteheads and blackheads, are caused by bacterial infection of the plug of sebum and dead skin cells within the sebaceous follicles. The general treatment for such infections is antibiotics, both topically and internally. Tetracycline has already been mentioned as a common internal antibiotic, and several forms of antibiotics are used in facial scrubs of which peroxides and benzoates may perhaps be rather severe for dry and sensitive skins.

3. The third phase is treatment of the causes of excessive sebum production. This is generally not entirely treatable since it is predominantly due to excessive hormonal activity at certain times of your life such as puberty, menstruation, pregnancy and menopause. However, your physician may offer treatments such as the contraceptive pill which should be used with care.

Other treatments include agents that aid desquamation, so preventing the irregular shedding of skin cells that lead to the mixture of sebum and dead skin cells that form the plug that is so easily affected by bacterial infection.

Together these three stages of acne treatment can, if not prevent the condition, certainly reduce its extent and have less of an effect on your skin, particularly if you are the off the oily skin type. Doctors will take your skin type into consideration when determining the best acne treatment for you, although all generally this will only be with respect to topical treatments: treatments that are applied to the surface of your skin.

There are also a number of herbal treatments which are used in the treatment of various stages of acne, and many sufferers find these equally as effective as the more traditional forms of topical applications as prescribed by physicians. However given that the treatment you use is safe according to your physician, any that works for you is the acne treatment that you should likely use, irrespective of your skin type.

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Colostrum and immunity
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Date: June 17, 2009 10:13 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Colostrum and immunity

In order to obtain a smooth running immune system, communication between cells is absolutely essential. To communicate between cells, the system uses hormone-like signal substances, which can often be found in colostrum. It has been found in studies that an immune response can literally be transferred from a donor to another recipient by simply feeding that person with an extract of leucocytes. This extract contained a factor that was capable of passing on the donor’s immunity to the recipient. Scientists and researchers still do not know the exact constituents of colostrum, as colostrum extracts have been estimated to contain more than 200 individual compounds which each play a role in the communication process.

Because an immature response within the immune system to an infection can take anywhere from ten days to two weeks to completely develop, colostrum is essential because it can reduce this delay in reaction time due to two factors it possesses: an inducer/helper function, and a suppressor function. The inducer function allows the body to develop a mature response in as little time as twenty-four hours. However, an overactive immune response to agents that are always present like pollens and the body’s own cells is not healthy. The suppression factor comes in here, as it helps to control hyper-reactive responses that commonly turn into allergies and autoimmune diseases. Together, all of this helps to keep the immune system and the body’s overall health in a balanced state.

An infant’s first food is usually a mother’s milk, which is full of nutrient-rich colostrum. Colostrum contains valuable components which help the immune system to communicate and pass information between the cells. There are agents passed through colostrum that are not species-specific, meaning that they are equally effective in one species as they are in another. Additionally, this means that these agents generally do not cause allergies.

Colostrum and its derivatives can be used for many conditions including herpes, hepatitis, chronic fatigue syndrome, candidiasis, cancer, type I diabetes, intestinal injury, autism, rheumatoid arthritis, AIDS, and the Epstein-Barr virus. Herpes, which is a commonly found disease in today’s world that manifests itself in recurrent outbreaks which are characterized by sores and other skin lesions. Colostrum has been found to decrease the frequency of herpes outbreaks, as well as shortening the duration of any outbreak that is experienced. Agents found within colostrum are specifically programmed to fight the hepatitis viruses and are even able to prevent the onset of hepatitis.

Because colostrum and its immune agents are able to effectively help the body combat a variety of pathogens, it is also believed that colostrum can help to fight conditions like chronic candidiasis. Cancer may be prevented and fought with the use of colostrum and its various agents. Diabetes, which is one of the world’s most widespread and debilitating disorder, is increasingly associated with dysfunction of the immune system. Research has shown that colostrum and its compounds may have the ability to reverse diabetes. Colostrum has also been proven in studies to reverse the effects of autism on a child to the extent that the child can return to a mainstream school and participate in social activities. The Epstein-Barr virus, which is associated with symptoms including extreme fatigue and headaches, may be affected by colostrum, as studies have shown the total remission of symptoms in patients with this virus.

Colostrum is an amazing substance. Fortunately, it can be found at your local or internet health food store in capsule or tablet forms for easy consumption. Always purchase name brands like Source Naturals, Kal, and Now Foods to ensure quality and purity of the product you purchase.

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First, the Painful Inflammation
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Date: April 03, 2008 12:43 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: First, the Painful Inflammation

Inflammation occurs because of the reaction of your immune system to what it perceives as being the presence in your tissues of dangerous foreign particles. Your immune system generally reacts to particles. Typical particles are bacteria and viruses, pollen, smoke, your own body cells that are not doing what they should, moulds and fungi, and various other things that can circulate in your blood.

There are several reasons for the immune system being activated, some of them historical due to your body having an imprinted memory of previous bacteria and viruses that it has dealt with, and others the reaction to new invaders that it has never met before, and for which your immune system creates antibodies to destroy. Another is the recognition of abnormal body cells that have to be destroyed before they can proliferate, and yet another is when the immune system gets confused and itself damages your own tissues such as in rheumatoid arthritis.

Whatever the cause, inflammation is a common result of the immune system going to work, and can be extremely painful. It can cause damage to our own joints, vascular system and major organs, although treatment of the inflammation does not reduce the effectiveness of the immune response. You can safely treat the inflammation with anti-inflammatories and painkillers without the condition getting worse.

Common physical manifestations of inflammation are the swollen and painful joints of rheumatoid arthritis (osteoarthritis is not an immune response), the swelling in the airway of asthma, the spots and swellings of measles and chickenpox, the lesions of psoriasis and the swelling and pain of abrasions and cuts that have gone ‘septic’ or ‘poisoned’. The latter two are simply examples of the effect of phagocytes and leucocytes on bacterial infection – the white blood cells and their cohorts!

The reason that inflammation causes pain is that it affects nerve endings, and causes pressure against the damaged tissues that initiated the immune response. Although regular painkillers can control the pain of inflammation to an extent, they are generally not the ideal treatment. Herbal treatments are not necessarily always the ideal treatments either, but boswellia is one herb that has been proved to be effective in reducing the pain of inflammation.

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A Periwinkle Extract Vinpocetine May Promote Cerebral Blood Flow
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Date: December 01, 2007 09:05 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: A Periwinkle Extract Vinpocetine May Promote Cerebral Blood Flow

Periwinkles form the plant genus Vinca, of which the lesser periwinkle and the greater periwinkle are the two members. They are also a form of dogbane, known for its alkaloid properties. Periwinkles are of interest to the medical profession due to their biosynthesis of a number of alkaloids that are used to protect themselves from bacteria and are also toxic to the herbivores that would otherwise eat them.

Many other plants produce alkaloids, perhaps the best known being poppy, that produces the alkaloid opium that is the precursor to heroin. The alkaloids of the periwinkle, however, have a much more beneficial use for mankind in their action on certain types of cancer such as Hodgkin’s disease, and also on the flow of blood to the brain.

The components of the periwinkle include vinblastine, which is used in the treatment of Hodgkin’s lymphoma, and it is the only plant known to produce the alkaloid, although only in very small quantities after synthetic seeding. This involves introducing modified tryptamines to the plant so that they produce the desired alkaloid, although only in quantities of 0.002% of the weight of the plant. Although small, this is still less expensive that synthesizing the alkaloid in a chemical plant rather than a biological one!

Chemists are now seeking more readily synthesizable alternative forms of the alkaloid that have the same effect, again using the periwinkle as a botanical chemical factory to provide them with a lead as to possible synthetic routes. However, it is for the application of another alkaloid of this amazing little plant that we are more concerned with here.

In addition to vinblastine, the periwinkle produces the alkaloid vincamine, a type of tryptamine that can be extracted from the leaves of the lesser periwinkle, the Vinca minor. This periwinkle has been used through the ages as an invigorating tonic and as an astringent to treat bleeding gums and sores in the mouth. Vincamine promotes the aerobic glycolysis that is essential to cerebral health.

Normal glycolysis, or the conversion of glucose to energy in the mitochondria of the cells of the body, occurs best in the absence of oxygen (anaerobic glycolysis). However, the brain produces up to and over 90% more energy through aerobic glycolysis in the presence of oxygen than through anaerobic. Hence one of the needs for such a rich supply of oxygenated blood being needed by the brain. As people grow older, or their brain tissue becomes damaged, then the supply of blood can be reduced and more and more anaerobic glycolysis is switched on. This results in an increasing loss of brain energy and hence brain function. Vincamine can reverse this effect, or at least maintain the status quo, and so enable people to maintain their brain function for longer.

It is also what is known as a vasodilator, and dilates the blood vessels in the brain allowing a greater blood flow. It is known to be beneficial in relation to tasks requiring focused concentration such as mathematical problem solving, and has also been found effective in the treatment of people with poor memory.

Vinpocetine (ethyl apovincaminate) is a derivative of vincamine, obtained by slightly modifying the molecule to produce a commercial form of the alkaloid. This possesses all of the beneficial effects of its precursor, including its positive effects on memory, believed to be due to the stimulation of serotonin production that improves the rate at which the brain can process information. Tinnitus, or ringing in the ears that has severely reduced the quality of life of so many people, can also be treated with vinpotecine.

Its vascodilation effect is thought to be through its action as a phosphodeaterase 1 (PDE1) inhibitor that results in an improvement in the plasticity of neurons. The mechanism is complex, but the end result is an improvement in the cognitive abilities of the subject. This is supplemented by the effect of vinpocetine on the calcium levels in the blood vessels. This renders them more plastic in much the same way that some anti-hypertension treatments work to reduce blood pressure by increasing the plasticity of the blood vessels by modification of their calcium levels. It can also reduce the viscosity of the blood through its action on the “stickiness” of leucocytes and so allow the blood to run more freely through the capillaries of the brain.

These effects have been demonstrated through double blind studies, and there is little doubt that vinpocetine helps to maintain a healthy cerebral circulation. So let’s have a recap on its various effects, and then finish with a summary of the conditions that the alkaloid can be used to treat or improve. The theory and biochemistry behind these effects is known, but is complex, but here are the major actions:

a) It improves blood flow by modifying the calcium content of the blood vessels and so improves their elasticity, hence allowing a freer movement of blood. In effect it helps the blood vessels to dilate easier.

b) It inhibits the enzyme PDE1 and by doing so helps to restore the elasticity of neurons in aging brain cells, allowing them to relax more and operate more effectively.

c) It promotes aerobic glycolysis, and so the rate at which the mitochondria of brain cells produce ATP (adenosine triphosphate) that is the chemical manifestation of energy.

d) It helps to maintain a good supply of glucose and oxygen in the brain to allow (c) to occur.

Not all of these may be separate effects, but the outcome is an improvement in conditions such as short term memory loss, dementia and other conditions associated with a reduction in the blood supply to the brain including Menière’s syndrome and vertigo. There is also evidence that it helps with hearing problems, macular degeneration of the eye, and fatigue.

It is a supplement that should be taken by the elderly to help with age-related memory problems, but has also been found to be beneficial in normal healthy people. The periwinkle extract Vinpocetine has been shown to have benefits, largely through an increase in the blood flow to the brain, and will be of use to anybody suffering from conditions that can be related to a deficiency in their cerebral blood supply.



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Butterbur Extract Fact Sheet
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Date: December 08, 2005 04:22 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Butterbur Extract Fact Sheet

Butterbur Extract Fact Sheet

Neil E. Levin, CCN, DANLA 8/1/05

LIKELY USERS: People wanting to support healthy blood flow to the brain and healthy neurological function 1-6,10 Those maintaining normal seasonal immune responses 7-10

KEY INGREDIENTS: 75 mg of Guaranteed Potency Butterbur Root (Petasites hybridus) Extract, min. 15 Sesquiterpenes as Petasines; 200 mg of Feverfew Leaf (Tanacetum parthenium) min. 0.4% Parthenolides

MAIN PRODUCT FEATURES: Butterbur (Petasites hybridus) is a native shrub of Europe, North America, and Asia that has been used by herbalists for centuries. Modern scientific studies have demonstrated that Butterbur supports healthy blood flow to the brain and healthy neurological function.1-6, 10 In addition, Butterbur may help to maintain balanced seasonal immune responses.7-10 In a synergistic base of guaranteed potency Feverfew leaf.11-26

ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: NOW Butterbur is free of harmful levels of Pyrrolizidine Alkaloids (PAs), the undesirable compounds naturally found in Butterbur, so it is safe to use regularly.

SERVING SIZE & HOW TO TAKE IT: Take one VCap one to three times per day, or as directed by your physician.

COMPLEMENTARY PRODUCTS: Magnesium, Ulcetrol, B-2, B-12, Fish Oil (EPA, DHA), SAM-e, Ginger, Ginkgo Biloba

CAUTIONS: None.

SPECIFIC: Do not discontinue use abruptly; taper off use if discontinuing. Discontinue use at least 14 days before surgery or oral surgery. Use with caution if you have ragweed allergies or blood disorders and let your physician know that you plan to use it before you take it. May be contraindicated for pregnant women.

GENERAL: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. Information given here may vary from what is shown on the product label because this represents my own professional experience and understanding of the science underlying the formula and ingredients. When taking any new formula, use common sense and cautiously increase to the full dose over time.

Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. REFERENCES:

1. Diener HC, Rahlfs VW, Danesch U (2004) The First Placebo-Controlled Trial of a Special Butterbur Root Exract for the Preventio of Migraine: Reanalysis of Efficacy Criteria. Eur Neurol 51:89-97.
2. Lipton RB, Gobel H, Einhaupl KM, Wilks K, Mauskop A (2004) Petasites hybridus root (butterbur) is an effective preventative treatment for migraine. Neurology 63:2240-2244.
3. Pothmann R, Danesch U (2005) Migraine Preventiuon in Children and Adolescents: Results of an Open Study With a Special Butterbur Root Extract. Headache 45:196-203.
4. Rapaport AM, Bigal ME (2004) Perventive migraine therapy: what is new. Neurol Sci 25:S177-S185.
5. Wu SN, Chen H, Lin YL (2003) The mechanism of inhibitory actions of S-petasin, a sequiterpene of Petasites formosanus, on L-type calcium current in NG108-15 neuronal cells. Planta Med 69(2):118-124.
6. Wang G-J, Wu X-C, Lin Y-L, Ren J, Shum AY-C, Wu Y-Y, Chen C-F (2002) Ca2+ channel blockin effect of iso-S-petasin in rat aoritic smooth muscle cells. Eur J Pharmacol 445(3):239-45.
7. Lee DKC, Carstairs IJ, Haggart K, Jackson CM, Currie GP, Lipworth BJ (2003) Butterbur, a herbal remedy, attenuates adenosine monophosphate induced nasal responsiveness in seasonal allergic rhinitis. Clin Exp Allergy 33:882-886.
8. Lee DKC, Haggart K, Robb FM, Lipworth BJ (2004) Butterbur, a herbal remedy, confers complementary anti-inflammatory activity in asthmatic patients receiving inhaled corticosteroids. Clin Exp Allergy 34:110-114.
9. Lee DKC, Gray RD, Robb FM, Fujihara S, Lipworth BJ (2004) A placebo-controlled evaluation of butterbur and fexofenadine on objective and subjective outcomes in perennial allergic rhinitis. Clin Exp Allergy 34:646-649.
10. (No Author) (2001) Petasites hybridus (Butterbur). Alt Med Rev 6(2):207-209.
11. Hayes NA, et al. The Activity of Compounds Extracted from Feverfew on Histamine Release from Rat Mast Cells. J Pharm Pharmacol. Jun1987;39(6):466-70.
12. 2 Groenewegen WA, et al. A Comparison of the Effects of an Extract of Feverfew and Parthenolide, a Component of Feverfew, on Human Platelet Activity In-vitro. J Pharm Pharmacol. 1990;42(8):553-57.
13 Capasso F. The Effect of An Aqueous Extract of Tanacetum parthenium L. on Arachidonic Acid Metabolism by Rat Peritoneal Leucocytes. J Pharm Pharmacol. Jan1986;38(1):71-72.
14. 4 Bejar E. Parthenolide Inhibits the Contractile Responses of Rat Stomach Fundus to Fenfluramine and Dextroamphetamine but not Serotonin. J Ethnopharmacol. Jan1996;50(1):1-12.
15. 5 Prusinski A, Durko A, Niczyporuk-Turek A. [Feverfew as a Prophylactic Treatment of Migraine]. Neurol Neurochir Pol. 1999;33(Suppl 5):89-95.
16. 6 Barsby RW, et al. Feverfew Extracts and Parthenolide Irreversibly Inhibit Vascular Responses of the Rabbit Aorta. J Pharm Pharmacol. Sep1992;44(9):737-40.
17. 7 Pittler MH, Vogler BK, Ernst E. Feverfew for Preventing Migraine (Cochrane Review). Cochrane Database Syst Rev. 2000;(3):CD002286.
18. 8 Pattrick M, et al. Feverfew in Rheumatoid Arthritis: A Double-blind, Placebo Controlled Study. Ann Rheum Dis. 1989;48:547-49.
19. 9 Makheja AM, et al. A Platelet Phospholipase Inhibitor from the Medicinal Herb Feverfew (Tanacetum parthenium). Prostaglandin Leukotri Med. 1982;8:653-60. 20. 12 Drug Identification Number Notification. Drugs Directorate, Therapeutic Products Division, Health Protection Branch, Health Canada . Ottawa , Canada
20. 12 Drug Identification Number Notification. Drugs Directorate, Therapeutic Products Division, Health Protection Branch, Health Canada. Ottawa, Canada.
21. 14 Newall CA, et al. Herbal Medicines: A Guide for Health Care Professionals. London: The Pharmaceutical Press; 1996:119-21.
22. 15 PDR for Herbal Medicines, 2nd ed. Montvale , NJ: Medical Economics Company; 2000:307.
23. 16 Pribitkin ED. Herbal therapy: what every facial plastic surgeon must know. Arch Facial Plast Surg. Apr2001;3(2): 127-32.
24. 17 Schmidt RJ. Plant dermatitis. Compasitae. Clin Dermatol. Apr1986;4(2):46-61.
25. 18 Heck AM, et al. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm. Jul2000;57(13): 1221-7.
26. 19 Newall CA, et al. Herbal Medicines: A Guide for Health Care Professionals. London : The Pharmaceutical Press; 1996:119-21.



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