Search Term: " recall "
PQQ is effective in combating neurodegeneration that can affect theaging brain
December 21, 2018 08:53 AM
A nutrient called Pyrroloquinoline quinone (PQQ) has shown potential for combating the degenerative neurological symptoms of Alzheimer’s, according to research published by Life Extension. Mice that were given a PQQ supplement developed smaller deposits of toxic proteins in their brains compared to the mice that did not, and also demonstrated better recall, memory, motor skills and learning relative to the control group. Other research suggests PQQ may help with Parkinson’s symptoms, and improve blood circulation within the brain.
"But there are many ways in which a person can reduce their risk of neurodegeneration as they age, like healthy eating."
Read more: https://www.naturalnews.com/2018-12-13-pqq-combats-neurodegeneration-that-can-affect-the-aging-brain.html
Improve memory and mood with curcumin: Study finds it boostscognitive function in those with mild, age-related memory loss
October 11, 2018 02:28 PM
There are some people who are finding that retaining their memory gets harder and harder with age. Some people deal with it better than others but when this moment comes, it is a tough pill to swallow. Many people do not want to face reality as they struggle to comes to terms with the fact that they are getting older. However, it happens to everyone. Now you can improve your memory with curcumin and more things.
"Results after the completion of the study indicated that participants who took curcumin had significantly improved their cognitive function than those who received the placebo – in particular, they had better recall, visual memory, and attention than the placebo group."
Read more: https://www.naturalnews.com/2018-09-23-improve-memory-and-mood-with-curcumin-cognitive-function.html
Taking vitamin B6 could help you recall dreams
May 24, 2018 09:16 AM
A study that was recently shown in the journal called Perceptual and Motor Skills proved that vitamin B6 supplements can actually help you recall dreams. They ended up giving 100 participants from Australia the vitamin right before bedtime in order to see if they could recall what they dreamed about the night before. It did not impact the color or vividness of the imagery, but they were clear and easy to remember. The participants each took 240mg of Vitamin B6 before bed.
"The study, published online in the journal Perceptual and Motor Skills, included 100 participants from around Australia taking high-dose vitamin B6 supplements before going to bed for five consecutive days."
Read more: http://www.thesouthasiantimes.info/news-Taking_vitamin_B6_could_help_you_recall_dreams-207247-Health-23.html
How Huperzine Helps With Memory
Memory refers to the process by which information is encoded, stored and retrieved when required. Encoding makes information from the outside world to be sensed in form of physical and chemical stimuli. In the first stage, information has to be changed in order to be put into the encoding process. Storage is the process by which the information is maintained over duration of time. The third of final stage is the retrieval process where the information stored is returned back to the consciousness.
One of the major problems that many people undergo is memory loss. This is a condition in which a person cannot recall information or events that they would be able to remember in normal circumstances. One of the most effective ways to help improve memory is by taking Huperzine. This is a drug that has proven to help boost memory and learning.
Here are some of the ways on how Huperzine help with memory:
1. Boost the level of acetylcholine
Acetylcholine is a very important transmitter in the brain responsible for carrying out several functions including those associated to memory and cognition. It is released into the space between two cells, where it then stimulates nerve impulses from one cell to the other. When acetylcholine fails to work effectively, several types of brain dysfunction occurs. A shortage of acetylcholine is known to be the common cause of memory loss, decreased intelligence and learning ability. Huperzine helps in reducing the breakdown of acetylcholine and boost the duration and strength of nerve impulse. It makes the neurotransmitter more available leading to better memory and improved overall brain functioning.
2. Protection against free radicals
Huperzine offers protection against free radicals that are known to be the major cause of modern diseases. It decreases the activity of heightened free radical activity in the brain. This goes a long way in reducing the risk of having memory loss. It has also proved to be effective in helping adolescents improve their learning abilities and memories.
Ginkgo Biloba A Modular Solution To Boosting Memory.
August 04, 2014 08:16 PM
Memory loss occurs when one loses the ability to remember information and events that you would normally be able to recall. It is usually distressing for the person affected and the family members.
Gingko Biloba Benefits
Ginkgo biloba is effective for memory aid as it improves blood flow to the brain. It can help with memory problems caused by dementia or Alzheimer's disease. It helps to prevent the progression of dementia symptoms. It also helps in the improvement in cognitive function. Taking ginkgo biloba leaf extract by mouth seems to improve thinking skills in elderly people with mild moderate age related memory loss or thinking problems. It improves short-term visual memory and speed of mental processing in non-demented people with age related memory loss and it can improve memory and speed of mental processing in people without memory loss.
Ingredients of Gingko Biloba
The active ingredients in ginkgo biloba are ginkgolides, bilobalides and flavonoids. It works by delaying the symptoms of dementia. Adding ginkgo biloba supplements may help battle cognitive impairments and memory loss associated with dementia since it encourages the growth and development of neural stem cells. It protects the neurons from oxidative damage by potentially preventing the progression of tissue generation in patients suffering from dementia. Ginkgo biloba extracts promotes growth in brain regions.
Due to its benefit of boosting memory, most doctors prescribe ginkgo biloba as the treatment choice for dementia and for age related memory dysfunction. It has been approved for symptomatic treatment of deficits in memory impairment, concentration difficulties and depression from organic brain disease. In conclusion, it is evident that ginkgo biloba extracts helps to stabilize and improve memory loss in several measures of social functioning and cognitive functioning in mixed or vascular dementia patients and Alzheimer's Disease. It might also improve memory and speed of mental processing in people without memory loss.
Does Broccoli Really Fight Cancer?
May 27, 2014 05:23 PM
What is a broccoli?
Cruciferous vegetables such as broccoli is known to have numerous health benefits within the body. In addition, many studies have proved that broccoli has another element known as sulforaphane that has cancer-fighting properties.
Benefits of broccoli
A recent study by the Oregon State University, suggested that sulforaphane is a powerful antioxidant in broccoli and many other cruciferous vegetables do have the power and the ability to kill cancer cells, thus leaving the prostate cells unaffected.
Sulforaphane is also another potent antioxidant that has the ability to inhibit HDAC enzymes known as histone deacetylase and play a vital role in suppressing tumor-like genes thus making a perfect solution to cancer treatment. HDAC in Cruciferous vegetables such as broccoli is known to have numerous health benefits within the body. In addition, many studies have proved that broccoli has another element known as sulforaphane that has cancer-fighting properties.
A recent study by the Oregon State University, suggested that sulforaphane is a powerful antioxidant in broccoli and many other cruciferous vegetables do have the power and the ability to kill cancer cells, thus leaving the prostate cells unaffected.
Sulforaphane is also another potent antioxidant that has the ability to inhibit HDAC enzymes known as histone deacetylase and play a vital role in suppressing tumor-like genes thus making a perfect solution to cancer treatment. HDAC inhibition is another very promising cancer treatment and many researchers have found that it is associated with broccoli. Cancer is often characterized by the inappropriate cell growth, however, HDAC inhibitors has the ability of restoring cells to normalcy in terms of function and thus the most effective cure of cancer.
Other studies have also demonstrated the cancer-fighting ability of the cruciferous vegetables. In the year 2009, Victoria Kirsh., of Toronto Cancer Care Ontario and her team discovered that eating vegetables and fruits in general was associated with the decreased prostate cancer risk, making it one of the best ways of enhancing health. This remarkable compound in broccoli is among the strongest anti-cancer elements in the body.
It is important to recall that you cook your broccoli in the best way possible since this will preserve the elements that helps in fighting cancer. In addition, Broccoli has myrosinase that helps in the formation of sulforaphane. You need to remember that Myrosinase is an element that can be destroyed through overcooking the broccoli. You should only steam it for 2 to 4 minutes. In conclusion, the above information should convince on the incredible ability to cure the cancer cells that are found within the body.
How L-Glutamine Increases Memory And Cognitive Functions!
January 20, 2014 09:26 AM
Assuming that you are one of the numerous people that experience the ill effects of cerebrum fogginess, weakness and even laziness, you can discover the easing you require since L-Glutamine enhances memory and cognitive capacities. This amino acid is extremely pervasive in a few parts of the mind, the spinal string, and even organs of assimilation and detoxification. These methodologies all work synergistically with one another to handle optimal health conditions that abandon you feeling extraordinary constantly. When you have ever battled to recall certain occasions, data, or basic portions, you have to adjust the way your cerebrum appreciates data, which might be adequately finished when you utilize L-Glutamine to upgrade memory capacity. This compelling cell reinforcement does everything, and revitalizes your cells so you profit from improved vigor levels for your health and against maturing necessities.
How the medicinal utilization of L-Glutamine enhances your memory
Presently you can encounter all the rushes of having the ability to recall again when you use this characteristic elective health supplement for sum figure quality and persistence. This animated amino acid works through protein combination and compound transformations in distinctive parts of the form which invigorate sound responses to happen. Engaging your psyche from the cell level up, L-Glutamine enhances memory and evacuates collections of smelling salts and nitrogen in the blood which at last influences the working of your cerebrum. Smelling salts is available when this fixing is changed over into glutamic acid which obliges certain measures of alkali. When you standardize these levels, the mind fogginess vanishes as your units accept fitting measures of oxygen and supplements for sound working.
Health points of interest of utilizing L-Glutamine to improve memory capacity
Furthermore, there are other sound motivating forces to utilize this part also. The point when this valuable substance is changed over into its hostile to oxidizing structure, it improves the benefit of the focal apprehensive framework, beginning at the cerebrum. It can likewise secure your nerves from harm because of hormones, chemicals, and extreme electrical indicators. When you utilize L-Glutamine to improve memory capacity, you are likewise diminishing the dangers of experiencing tension, melancholy, and a large portion of its identified indications in view of its stimulant qualities. This elective health supplement impacts the pituitary organ to discharge certain chemicals, indicators, and hormones all around the figure to equalize out physiological capacities.
Together Glucosamine, Chondroitin, and MSM Fight The Battle Against Joint Pain
December 18, 2013 03:36 AM
What Do Glucosamine / Chondroitin / MSM Have In Common?
In today's cultural, there seems to be a remedy for almost any ailment. If you have a headache then just take two acetaminophen every four to six hours. Maybe you have broken your arm and can recall the pain medication that was prescribed by your doctor. Unfortunately, as far as science is concerned,not a single treatment works 100% of the time. There is always some sort of relapse period during which, if an individual forgets to take their medicine the pain will return.
How Does Glucosamine Fit Into The Picture
Hundreds of individuals suffer from some sort of joint pain that is found in the knee, hip, or shoulder area. The chance is high that you are one of those people who have been diagnosed witharthritis, osteoarthritis, gout, or bursitis. Most likely, you have also been written a prescription from your doctor for anything from a muscle relaxer to an anti-inflammatory. Be aware of the fact that these medicines will reduce pain and swelling but only for a short period of time. What happens when the pain relapses and you cannot take anymore? Perhaps, you should consider a nutrional supplement that will help your body fight from within.
What About Chondroitin
By itself, glucosamine lubricates the connective tissues of the body. Although, glucosamine cannot work without another natural compound called chondroitin. The body uses glucosamine to produce chrondroitin which is an example of a glycosaminoglycan. Better known as chondroitin sulfate, it must mix with other proteins in the body to create proteoglycans which are found in all connective tissues.
Why Does MSM Sound So Similar
Just like glucosamine and chondroitin , also known as methyl sulfonyl methane , MSM is known to help aid in the fight against osteoarthritis and joint pain. It is naturally found in humans and in certain plants and animals. Usually MSM is paired with glucosamine and chondroitin in a pill or capsule form.
March 23, 2009 01:56 PM
Our memory is as natural to us as breathing. An ability we all have, but don’t often think of, it doesn’t seem to cross our mind until we perceive that we are losing the ability. Memory lapses are an annoyance in themselves, but the anxiety that often comes along with them seems to be even worse. We often wonder if our memory problems are a symptom of some other problem like midlife depression, arteriosclerosis, or even Alzheimer’s disease. Although Alzheimer’s disease is a fairly common disorder among older people, one must realize that most memory lapses have nothing to do with Alzheimer’s disease.
Generally, it is believed that increasing age brings about an increased likelihood of developing memory loss. The mildest form of this illness is called age-associated memory impairment. This is characterized by one’s perception of his or her own memory loss and it is estimated that it is experienced by 40 percent of Americans over the age of sixty-five. Not all memory loss is attributable to aging, as occasional memory lapses are a natural normal part of life at almost any age, and are not likely to precede serious memory loss. With a proper diet, nutrition, and memory use, the memory should remain sharp and active well into one’s nineties or beyond.
One big reason why people suffer from memory loss is an insufficient supply of necessary nutrients to the brain. The life of the body is in the blood, as it literally feeds and nourishes every cell within our bodies. Only certain substances are allowed to pass from the bloodstream into the brain, thanks to the protective envelope that is known as the blood-brain barrier. If the blood is thick with cholesterol and triglycerides, the amount of nutrient-rich blood that can pass through the blood-brain barrier decreases. This can result in the brain becoming malnourished over time.
The functioning of the brain also depends upon substances that are referred to as neurotransmitters, which are brain chemicals that act as electrical switches in the brain and are responsible for all the functions of the body. If the brain does not have an adequate supply of neurotransmitters, or the nutrients to make them, it starts to develop something similar to a power failure or a short circuit. If you are trying to recall as specific fact or piece of information and your mind goes blank, it is likely that the above “short circuit” has occurred.
There are many other factors that are involved in the deterioration of the memory. One of the most important is exposure to free radicals, which can cause huge amounts of damage if the memory is unchecked. Alcoholics and drug addicts often suffer a great deal of memory loss, with alcoholics being notorious for huge memory gaps that occur even though they are conscious. Allergies, candidiasis, stress, thyroid disorders, and poor circulation to the brain can also contribute to memory loss, while hypoglycemia can play a role in memory loss as well, as the brain requires that the level of glucose in the blood fall within a specific narrow range. Wide swings in blood sugar levels affect brain function and memory.
The following nutrients are beneficial in dealing with and preventing memory loss: acetylcholine, boron, DMAE, garlic, huperzine A, lecithin granules, manganese, multivitamin and mineral complex, omega-3 fatty acid complex, phosphatidyl choline, phosphatidyl serine, SOD, vitamin A, vitamin B complex, vitamin B3, vitamin C, vitamin E, zinc, acetyl-l-carnitine, l-glutamine, l-tyrosine, coenzyme Q10, DHEA, DMG, melatonin, NADH, pregnenolone, RNA and DNA, Brahmi, ginkgo biloba, anise, blue cohosh, ginseng, gotu kola, and rosemary.
All of the above mentioned as well as formulas tailored to help improve memory can be found in capsule, table, or power forms. Remember, only look to name brands such as Solaray, Source Naturals and Natures Plus for quality products. Memory vitamins and herbs can be found at your local or internet health food store.
*Statements contained herein have not been evaluated by the Food and Drug Administration. Vitamins and herbs are not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.
May 30, 2008 02:43 PM
You're ready to leave the house, you're already running late and you can't remember where you put the keys. You try retracing your steps, check all of your coat pockets and start to panic. You can't remember where you put them or where you last saw them. Does this sound familiar? Do you have trouble focusing clearly? Our thinking process slows as we age. It is as if a cloud lingers over our brains, making it impossible to think clearly.
Improve Your Mind with Bacopa Extract
There is help for people who can't learn or think as fast as they once could. An all-natural product, bacopa extract, has been used for thousands of years as a "brain tonic" in India. It has been used to enhance memory, learning and concentration. This aquatic plant has strong antioxidant powers. It helps people retain new information by stimulating the brain's neurotransmitters.
Bacopa extract can be used for:
* Relieving anxiety
It also has antispasmodic and anti-allergic properties.
Clinical Study Proves Benefits of Bacopa Extract
A study reported in the August 2002 issue of Neuropsychopharmocolgy, "Chronic Effects of Brahmi (Bacopa) on Human Memory," stated positive results. The study found that "Brahmi decreased the rate of forgetting of newly acquired information."
This means you can learn faster and think more clearly when taking a bacopa extract. Consider, for example, a situation in which you are meeting people for the first time and being introduced to them by name. Will you be able to remember any of their names when you see them across the room in 10 minutes? How about if you run into them a few weeks later?
What if you couldn't remember their name, or worse, called them by the wrong name? That doesn't send a very good first impression. Or maybe you have been on the receiving end of this and have been repeatedly called the wrong name by someone. You know how irritating it can be. Bacopa extract can help in this type of situation. Taken daily over an extended period of time, you will see a difference in the amount of information you can retain. You won't have to struggle so much to recall where you left your keys or the name of the person you just met.
Studies have shown that bacopa extract is effective for mental acuity. It helps by smoothing neurotransmitters and relaxing the brain. It has no known side effects and is deemed safe for children, as well.
Pair Bacopa Extract with a Healthy Lifestyle for Best Results
As with any natural supplement, bacopa will not improve your mental health unless it is accompanies by healthy lifestyle choices. Make sure you get the proper rest your body needs, daily exercise and good nutrition. Furthermore, it is important to exercise your brain. Find ways to challenge your mental alertness on a daily basis. Combine this with a daily dose of bacopa extract and you will see improvement in the clarity of your thinking.
May 28, 2008 03:25 PM
Phosphatidylserine (PS), a phospholipid, and DHA, an omega-3 fatty acid, are major components of cell membranes, particularly the membranes of nerve cells. They facilitate the electric signals that are the basis of neuron communication, supporting memory, mood, concentration, stress control and other cognitive functions. This DHA conjugate form of PS is believed to increase the delivery of this vital compound to the brain, supporting advanced brain protection and enhanced cell function.
• PhosphatidylSerine is a phospholipid essential to the brain’s structure and function. DHA is an omega-3 fatty acid, well known for supporting healthy cognitive function.
• The combination of PS and DHA is designed to function like animal phospholipids: supporting healthy cognitive function including memory, learning, comprehension, and word recall.
• With Phospatidylserine/Dha Optimized, P-S from soy is conjoined with DHA from fish oil. This replicates our natural, healthy neuron membranes.
1 capsule contains:
Suggested Use: 1 capsule three times daily with meals for the first 8 weeks, then 1 capsule daily with a meal thereafter.
Bioflavonoids: Boost Your Brain and Circulatory Health
January 17, 2008 01:16 PM
Bioflavonoids are most commonly praised for their antioxidant properties. They were first identified in the 1930’s by Albert Szent-Gyorgyi, Ph.D., a Nobel laureate. They are thought to prevent the breakdown of vitamin C in the body, and they also boast their own antioxidant capabilities. Over 5000 different bioflavonoids have been identified in nature. They are classified into categories including flavones, anthocyanidins, flavones, flavonols, isoflavones and flavans. Science is still discovering new types and their healing properties every day. The best part about them is that they are all natural and very powerful.
For example, scientists have been promoting the amazing benefits of the antioxidant found in dark chocolate. It is called epicatechin, and it is an excellent bioflavonoid for heart health. Studies show that it helps maintain healthy blood vessels. Antioxidants in dark chocolate are also believed to lower high blood pressure, according to a study published in the Aug. 27, 2003 edition of The Journal of the American Medical Association.
Rutin and quecertin, both found in red grapes, are also linked with a healthier circulatory system. A study conducted at the University of Wisconsin in Madison in 1995 found that “the antioxidant and platelet inhibitory properties of other naturally occurring compounds in the wine the consumption of flavonoid-containing foods and beverages may retard atherogenesis and prevent thrombosis on a daily basis.” Translated into common terms, the researchers concluded that bioflavonoid may slow artery and vein degeneration and prevent blood clotting.
The American Heart Association feels that this area of research is very promising. Their website states, “Phytochemicals are chemicals found in plants. Plant sterols, flavonoids and sulfur-containing compounds are three classes of micronutrients found in fruits and vegetables. These compounds may be important in reducing the risk of atherosclerosis, which is the buildup of fatty deposits in artery walls.”
As far as healthy brain function is concerned, bioflavonoid is thought to help with microcirculation in small vessels throughout the body. You might recall seeing ginkgo biloba in the news. It has been shown to improve memory with its powerful bioflavonoid in numerous studies. What makes ginkgo especially significant is that its bioflavonoids have a stronger potency than many other bioflavonoids, and it seems to have specific benefits in the capillary beds of the brain.
The National Center for Biotechnology Information recently reported the following on their website: “Flavonoids were shown to activate key enzymes in mitochondrial respiration and to protect neuronal cells by acting as antioxidants, thus breaking the vicious cycle of oxidative stress and tissue damage. Furthermore, recent data indicate a favorable effect of flavonoids on neuro-inflammatory events.” In other words, bioflavonoid is thought to help protect your brain cells from degeneration, and recent data shows that they may also reduce swelling.
Researchers are eager to discover all the healing properties bioflavonoids possess. Modern medicine is now faced with an all natural group of chemicals found in plant pigments that may prove to be effective in preserving brain function and promoting cardiovascular health. This is fantastic news for people that prefer natural supplements over expensive prescription pills. Current research shows that these chemicals have significant powers for enhancing overall health. In fact, many researchers advocate including bioflavonoid supplements in your daily health maintenance plan.
Reduce Your Cholesterol With Natural Vitamins
July 12, 2007 08:58 AM
Thanks to the excellent efforts of health education organizations like the American Heart Association, we’ve learned a lot about cholesterol and how it affects our health.
We know: high cholesterol levels increase our risk for heart attacks and strokes: lowering our cholesterol levels will reduce this risk and keep our hearts and blood vessels healthy; and that diet, weight loss, and exercise will all help us in our quest to lower our cholesterol levels. We also know at times, despite these good efforts, some people’s cholesterol levels are still too high.
Prescription drugs to lower cholesterol are now available and they are heavily advertised by the pharmaceutical companies that make them. What the commercials neglect to say is these medications, collectively called statin drugs, have some serious side effects. Statin drugs can cause elevations in liver enzymes, an indication of liver irritation. They are associated with myopathy, a painful disorder of muscle inflammation and muscle degeneration. Ironically, statin drugs significantly reduce CoQ10 levels in the body, a deficit that can lead to heart disease.
Statin drugs have also been linked to a rare and at times, fatal condition called rhabdomyolysis. Because of this alarming link, the makers of cerivistatin, a popular stain drug, recalled this medication from the market on August 8, 2001. The Food and Drug Administration a greed with the recall and supported the decision.
Thankfully, there is a safe solution to the dangers of high cholesterol levels. A natural dietary supplement is now available that can lower cholesterol very effectively without any harmful side effects. Backed by many years of scientific research and clinical study, pantethine and plant sterols, also known as phytosterols, are nature’s answer to dangerous prescription cholesterol lowering medications.
To understand how pantethine and plant sterols work to lower cholesterol levels, we need to first review what we know about cholesterol and heart disease.
Q. What exactly is cholesterol?
A. Cholesterol is a soft, waxy, fat-like substance found in every cell of the body. We need cholesterol to help digest fats, strengthen cell membranes, insulate nerves, and make hormones. Cholesterol is made primarily in the liver but also by cells lining the small intestine and by individual cells in the body. While our body makes all of the cholesterol we actually need (about 1,000 milligrams a day), we also get additional cholesterol from foods we eat.
The highest source of cholesterol are egg yolks and organ meats such a liver and kidney. No plant-derived food contains cholesterol, not even peanut butter or avocado, even though these foods are high in fat. However, all foods from animal sources such as meats, poultry, fish, eggs, and dairy products contain cholesterol.
Q. How does cholesterol cause heart disease?
A. Although cholesterol serves many important functions in the body, too much cholesterol in the bloodstream can be dangerous. When blood cholesterol reaches high levels, it builds up on artery walls, increasing the risk of blood clots, heart attack, and stroke.
The heart is a muscle, and like all muscles, needs a constant supply of oxygen and nutrients. The bloodstream transports these nutrients to the heart through the coronary arteries. If the coronary arteries became narrowed or clogged by cholesterol and fat deposits (artherosclerosis) and cannot supply enough blood to the heart, the result is coronary heart disease (CHD). IF not enough oxygen-carrying blood reaches the heart muscle, a sharp, sudden chest pain (angina) may occur. If the blood supply to a portion of the heart is completely cut off by total blockage of a coronary artery, the result is a heart attack. This is most often caused from a blood clot forming on top of an already narrowed artery.
Q. What is LDL and HDL cholesterol?
A. Cholesterol and other fats can’t dissolve in the blood and, therefore, can’t travel on their own. They have to be transported to and from the cells by special carriers called lipoproteins. The two major lipoproteins are low density lipoproteins (LDL) and high density lipoproteins (HDL). LDL is most often referred to as the “bad” cholesterol whereas HDL is known as the “good” cholesterol.
LDLs carry cholesterol throughout the body to the cells. LDLs cause artherosclerosis by clogging up our arteries with the continual buildup of fat. HDL, on the other hand, prevents this fat buildup within arterial walls, by carrying it away from the arteries, to the liver where it is eventually processed and eliminated.
Q. What are triglycerides?
A. Triglycerides are fats used as fuel by the body and as an energy source for metabolism. Triglyceride levels fluctuate easily, changing after every meal. Increased levels are almost always a sign of too much carbohydrate and sugar intake. Triglycerides in high amounts make the blood more sluggish and less capable of transporting oxygen, particularly through the small blood vessels. High triglycerides, along with high LDL “bad” cholesterol, are considered strong and independent risk factors for cardiovascular disease, leading to a heart attack or stroke.
There are several medications physicians can prescribe for people with elevated triglyceride levels. Some of the most effective (as well as the most harmful) are the statins. The powerful, all-natural combination of pantethine and plant sterols can safely and, just as effectively, lower both triglycerides and LDL “bad” cholesterol and increase HDL “good” cholesterol.
Q. What is pantethine and how does it lower cholesterol?
A. Pantethine, a form of pantothenic acid (also known as vitamin B5) is found in foods such as liver, salmon, and yeast. Pantethine lowers cholesterol by blocking its production.
Cholesterol synthesis, or the production of cholesterol in the human body, is an incredibly complex process. It involves many biochemical reactions and enzymes activity requiring several steps.
Studies have shown that pantethine inhibits several of these enzymes and coenzymes. It blocks the activity of one coenzyme involved in cholesterol synthesis, HMG-CoA, by about 50%. This results in significantly lower cholesterol production. But, that’s not all. To compensate for the lowered cholesterol production, the liver pulls LDL out of the bloodstream. The end results? Studies have shown that on average, pantethine can lower total cholesterol levels by 16%, LDL cholesterol levels by 14%, serum triglycerides by 38%, and can raise HDL cholesterol by 10%.
Q. What are plant sterols and how do they lower cholesterol levels?
A. Plant sterols are the fats of plants. They are found in nuts, vegetable oils, corn, and rice. Plant sterols are structurally similar to cholesterol and are able to act as a stand-in for cholesterol and block its absorption.
The liver receives about 800 mg of cholesterol every day from intestinal absorption. Cholesterol is absorbed from the intestines through receptor sites – special channels that are shaped exactly like cholesterol molecules. The cholesterol enters these channels and is then absorbed into the bloodstream. Because plant sterols look like cholesterol, they fit perfectly into these channels. The cholesterol, being blocked from absorption, remains in our intestines where it is eventually excreted.
If we eat enough plant sterols, the amount of cholesterol transported from the intestinal tract to the liver is greatly reduced. And, just like pantethine’s effect on the liver, this cholesterol reduction causes the liver to pull LDL cholesterol out of the blood, reducing both total and LDL cholesterol levels.
Q. Can’t we get the benefit of plant sterols and pantethine just by eating those foods that contain them?
A. These amounts of plant sterol and pantethine found in food just aren’t enough to have much of an effect on our health. In order to lower cholesterol levels, we need to take a concentrated combination of pantethine and plant sterols in just the right ratio.
Plant sterols are bound in fibers in the plants. Even if we ate lots of raw fruits and vegetables, we wouldn’t be getting many of these beneficial plant fats. There are also several forms of plant sterols. Some ratios of these plant sterols are more beneficial than others. On the average, we eat 160 to 360 mg of plant sterols a day.
While pantethine is found in several food sources, it is difficult to get beneficial amounts from our food. There are about 12 mg of pantethine in 3 ounces of brewer’s yeast and 8 mg in an average serving of liver.
Q. How much pantethine and plant sterol combination should I take?
A. Many studies have examined the effects of pantethine and plant sterols on cholesterol levels resulting in the determination of the most effective amounts to take of these heart healthy nutrients.
Manufacturers of high quality nutritional supplements offer pantethine combined with plant sterols in the most beneficial ratio as determined by the research. The best results are obtained by taking a combination of 400 mg of plant sterols and 200 mg of pantethine three times a day.
Q. Should only people with actual heart disease or those with high cholesterol levels be concerned about cholesterol?
A. No, recent studies have shown that cholesterol lowering in people without heart disease greatly reduces their risk for ever developing CHD, including heart attacks and artherosclerosis. This is true for those with high cholesterol levels and for those with average cholesterol levels.
Most physicians would never consider prescribing statin drugs to people without actual heart disease or high cholesterol levels because of the many health risks of the drugs. But the combination of pantethine and plant sterols can naturally and very effectively help those people with heart disease, high cholesterol levels, high triglyceride levels (or all three!) as well as those of us just wanting added “health insurance” for our hearts.
Q. Are pantethine and plant sterols safe?
A. Yes, both pantethine and plant sterols are very safe. Some people may experience some mild stomach upset when they first take pantethine. Taking the combination of pantethine and plant sterols with meals generally solves this problem.
Americans have listened, learned, and most importantly, taken to heart the vast and vital information on the need to keep our cholesterol levels under control. The result? More and more Americans are lucky enough to die of old age. The Centers for Disease Control recently released a report stating that the average American life expectancy has reached a new high of 76.9 years, thanks in no small measure to fewer people who are dying from heart disease,
The authors of this report stated that we could push our life expectancy even higher. We can attain healthy, old age by eating right, exercising regularly, and taking other simple steps to promote good health and prevent serious illness and heart disease. Taking the all-natural combination of pantethine and plant sterols is one simple, yet powerful step, to keep our hearts and blood vessels healthy for a long, long time.
Memory And Focus
May 08, 2007 02:05 PM
Memory & Focus
Some people think getting older often means getting slower. It’s true that as we age, we may find we can’t walk quite as fast, climb as many flights of stairs, or play sports as hard as we could when we were twenty. However, we k now that a healthy diet, regular exercise, and the right dietary supplements can make a huge difference in our health, strength, and mobility as we age.
This is true for our mental abilities as well. We may not think as quickly as we used to, might misplace our keys more often, and experience more “tip-of-my-tongue” word searches. These so-called “middle-aged moments” most often have minor consequences: a missed appointment or the forgotten name of an acquaintance. However, in a small number of cases, these mental slips can also be the first sign of serious diseases of aging, such as Alzheimer’s disease of other dementias.
The good news is, just like our physical health, we can improve how we function mentally. Eating healthy foods, taking the right supplements, and participating in regular mental exercise can significantly increase our mental endurance, improve our memory, and optimize our ability to focus.
In fact, groundbreaking and ongoing research has discovered that specific herbs and vitamins, particularly Ginkgo Biloba, Bacopa monnieri, folic acid, vitamins B6 and B12, and the important co-enzyme and antioxidant, alpha lipoic acid, all have powerful effects on memory and focus. These nutritional supplements have been scientifically shown to quickly reduce mild age-related memory chances, as well as greatly reducing the risk of developing more serious problems like Alzheimer’s disease, Parkinson’s disease, or other brain diseases later on in life.
Q. What is the difference between age related memory decline and dementia?
A. As we get older, our nerve cells need more time to spark and connect, slowing the process of bringing memories and events to mind. Another theory is that, as we age, we accumulate more knowledge and memories. The mind then has to sort through much more data to reference a memory. Almost everyone middle-aged and older notices this slowdown. Memory decline and problems with mental focus are a normal part of aging.
While it’s true that the older we get, our chances of developing Alzheimer’s disease increase, this illness is not a normal part of aging. Alzheimer’s is an irreversible, progressive dementia that slowly kills nerve cells in areas of the brain where memory, learning, though, and language take place. Often first appearing as people begin retirement, Alzheimer’s disease makes the “golden years” a time of loss and devastation. Memories vanish, relationships are erased, and independence is gradually lost.
After Alzheimer’s disease, the second most common cause of dementia in older people is multi-infarct dementia. Caused by a series of mini-strokes that damage or destroy brain tissue over time, multi-infarct dementia usually affects people between the ages of 60 and 75. Men are slightly more at risk. High blood pressure is the most significant risk factor for multi-infarct dementia.
Multiple sclerosis, Parkinson’s disease, strokes, Huntington’s disease, Creutzfelt-Jakob disease, and alcoholism can also cause progressive and irreversible dementia.
While normal age-related memory and focus loss may mean we can’t remember where we put our car keys, Alzheimer’s disease and other dementia may mean we can’t remember what our car keys are used for.
Q. Are any types of memory and focus loss reversible?
A. Yes. As women enter menopause, they frequently experience trouble remembering. This memory interference is caused by hormone fluctuations and can affect speech, thinking, and attention. Symptoms of menopause-related memory loss and poor focus include recognizing faces less well than in the past, missing scheduled appointments, and misplacing articles. Once a woman passes through menopause, her ability to remember and focus most often improves.
Certain medications, such as the heavily prescribed cholesterol lowering drugs called stains, can temporarily interfere with memory. Low vitamin B levels, artherosclerosis (hardening of the arteries), and thyroid disease can cause disruption of mental focus and memory loss. These problems usually resolve with treatment of the underlying disorder.
A certain type of stoke, called a transient ischemic attack (TIA) can cause memory loss that may be reversible. A TIA is a brief episode of stroke symptoms that come on quickly. Sometimes referred to as a “mini-stroke” or “warning stroke,” a TIA is caused by a temporary interruption in the blood supply to the brain. But, unlike a stroke, a TIA does not lead to permanent brain damage. While a TIA is usually short-lived, it is likely to occur again if not properly managed and can be a warning of future stroke.
Q. I seem to forget a lot of things. How can I be sure I don’t have Alzheimer’s disease or some other dementia?
A. If you, or other around you, are concerned about your memory, you should be examined by your health care practitioner. Once the cause of your memory and focus problem is diagnosed, treatment can begin. All causes of memory loss and mental focus disruption can be treated, even Alzheimer’s disease. While presently irreversible dementias cannot be cured, the progression of the disease may be slowed, and in some cases, stopped..
Research on memory loss and mental focus disruption has increased dramatically in the past few years. Discoveries regarding Alzheimer’s disease and other dementias, as well as age-related loss of memory and focus have recently been made. Most importantly, many new treatment options, including the use of nutritional supplements, have been developed.
Q. How can nutritional supplements improve memory and focus?
A. Several herbs and vitamins have been demonstrated to improve memory and mental focus. While some nutritional supplements work now to improve memory and focus, others work to prevent problems we might develop later.
One of the most researched herbs, Ginkgo biloba, has been found to be effective in improving currently experienced memory and focus loss; in other words, problems we are having now. Ginkgo has been studied in individuals who have age-related memory loss, as well as in those with Alzheimer’s disease and other dementias. It seems that ginkgo can improve many brain functions, such as speeding up memory recall, protecting brain cells from chemical changes and free radical damage, improving blood flow to the brain, and helping nerve cells communicate with each other better.
Several studies examined ginkgo’s effect in healthy people who were experiencing normal age-related memory and focus problems. They determined that ginkgo improved memory, attention, and clarity of thinking. Ginkgo can also help restore memories that may be lost in TIAs, those mini-strokes that were discussed earlier.
In studies of individuals with Alzheimer’s disease, the results showed that ginkgo slowed down the disease in those severely afflicted and actually improved those with very mild or moderate disease. In one of these studies, ginkgo was compared to four prescription cholinesterase inhibitors, medications commonly used to treat individuals with Alzheimer’s disease. Using written mental tests, the researchers found that ginkgo worked just as effectively as the prescription drugs. While those taking one of the cholinesterase inhibitors dropped out of the study because of disturbing side effects, ginkgo had no side effects and improved symptoms equally as well.
Q. Hoe does Bacopa monnieri help memory and focus?
A. Like ginkgo, bacopa works on the memory and focus problems we are experiencing now. Bacopa grows in
Q. How does alpha lipoic acid help memory and focus?
A. Alpha lipoic acid (
Researchers have discovered unmistakable free radical damage in Alzheimer’s disease. Accordingly,
In a recent study, people with Alzheimer’s disease were given tests that measured through and memory. They were then given
Q. How do vitamins B12 and B6 help memory and focus?
A. Vitamin B6 is an essential nutrient in the regulation of nerve transmissions. It is required by the nervous system for normal brain function, and it may also help with mood.
Researchers have learned that people with Alzheimer’s and other dementias (including Parkinson’s disease) have elevated homocysteine levels. IN fact, t he amount of homocysteine in the blood corresponds to the severity of the disease. Most people with a high homocysteine level don’t have enough folate, vitamin B5 or vitamin B12 in their diet. Replacing these vitamins helps return the homocysteine level to normal.
Reducing homocysteine levels may prevent the occurrence of Alzheimer’s disease, or other brain diseases, and improve the symptoms of those already afflicted.
Q. What about folic acid?
A. Folic acid has long been recognized as a vital nutrient for the brain and spinal cord. Recent research has demonstrated that folic acid has significant importance in Alzheimer’s disease.
An ongoing study of Alzheimer’s disease that began in 1986 has been studying 678 members of the School Sisters of Notre Dame in the hopes of learning how the disease develops, how it might be prevented, and how to treat it. Data collected in the study includes biographies the sisters wrote upon entrance to the order, blood samples from the sisters while they are living, and information gained from the voluntary donation of their brains after death.
Aptly named the “Nun Study,” ground breaking discoveries have already been made. It seems that diet and nutrition have a dramatic influence in the development of Alzheimer’s disease. Sisters who had high levels of folic acid showed little evidence of Alzheimer’s-type damage in their brains after death. And, those nuns who had Alzheimer’s disease in spite of high folic acid levels had profoundly less brain damage from the disease. In fact, some sisters who had no outward evidence of Alzheimer’s disease while they were living had surprisingly extensive damage in their brains after death.
Q. Besides taking ginkgo, bacopa, B vitamins, folic acid, and ALA, is there other things I can do to prevent Alzheimer’s disease?
A. You may not know if you have a serious B-vitamin deficiency. Routine lab work does not measure the amount of B vitamins in your blood. You might want to ask your health care practitioner to have your B vitamin level in your blood measured, especially if you are having memory and focus problems. Keep in mind that this type of lab work is fairly expensive, however.
Supplements do not replace the need for a healthy diet, especially a diet with high levels of fruits, vegetables, whole grains and omega-3 fatty acids. Keeping your body healthy helps keep your brain healthy as well.
It also seems that the use-it-or-lose-it theory applies to our brain as well as our body. Research has shown that people who seek opportunities to keep mentally active, such as reading books, newspapers, and magazines, solving crossword puzzles, playing card games, and visiting museums, lower their risk of Alzheimer’s disease.
Dealing with age-related memory loss may be both frustrating and frightening. As the population of
In fact, more and more research shows prevention of Alzheimer’s disease and other dementias is a reality. And age-related memory loss can successfully be improved as well. Taking the scientifically validated nutritional supplements ginkgo, bacopa, vitamins B6 and B12, folic acid, and
Now Foods -QUALITY- High Standards and Attention to Detail
December 27, 2005 09:00 AM
QUALITY “High Standards and Attention to Detail”
As you shop for dietary supplements you’re faced with an almost dizzying array of choices. Naturally, every product claims to be this, that and the other. But you’ve heard the stories in the media of products that don’t live up to their claims. So how do you know who’s telling the truth? Perhaps a better gauge of a product’s quality is the manufacturer and their history. Do they have a legacy of producing quality goods? How long have they been in business? Is their track record good or do they have a history of product recalls and bad press? If you’re responsible for your family’s health and well-being, it pays to do your homework when it comes to the products you purchase for them. NOW® Foods has been manufacturing dietary supplements and whole foods for 35 years.
Companies that thrive and continue to grow for this long don’t do so because they produce poor quality products. They do so by maintaining extremely high standards and paying special attention to every detail, which is the secret to product quality. At NOW® Foods, these high standards and attention to detail are evident in every aspect of our operations, from receiving to production to finished goods, just as they have been for 35 years. You’re committed to buying only the best for your family, and we’re committed to supplying only the best for our customers.
Quality products are made using the highest quality ingredients. NOW Foods purchases raw materials from only the most reputable vendors, who are required to provide detailed specification sheets and lot-specific certificates of analysis for every shipment we receive. These documents provide information on the quality of the raw material and the various analyses used to verify that quality. Shipments that do not meet our quality standards are sent back to the manufacturer with a point by point report card of why the shipment was refused. We simply don’t just accept every shipment that’s delivered to our dock – no ingredient gets a free pass into our production facility. In addition, we also perform random vendor audits throughout each year to ensure that they’re meeting our stringent quality standards. NOW ® Foods is always vigilant when it comes to quality, just as you are. Another way we maintain high quality standards is by choosing to buy and incorporate registered and/or trademarked ingredients into our products. Each of these ingredients are exclusively produced by a company that owns proprietary manufacturing rights and licenses selected companies like NOW® to use these top quality ingredients in their products.
These registered/trademarked ingredients must undergo even more rigorous analysis and controls than other ingredients, and so offer additional assurance that products containing them are properly manufactured and labeled. Additionally, to maintain the integrity of their ingredient’s reputation, the trademark owner will independently test finished products from manufacturers to verify the quality meets their standards and the label claim of the company licensed to use it. You may be familiar with some of the trademarked ingredient NOW® uses such as, Ester-C® vitamin C, Chromemate® Chromium and L-Carnipure® Carnitine.
Scientific analysis of ingredients is extremely important to ensure the integrity of any dietary supplement. NOW Foods has made substantial investments in the development, construction and staffing of numerous inhouse laboratories, including an advanced instrumental analysis laboratory, a “wet lab” and a state-of-the-art microbiology lab. This saves us the time and expense of having to send samples out to commercial labs for analysis. While we use independent labs to verify our in-house test results, our capabilities allow us greater control over product quality and quicker approval of raw material shipments for production, which means fresher products for consumers. Our investment ensures that NOW® will be able to meet ever-increasing demands for accurate product analysis and outstanding product quality. NOW® is unique in the industry in that we annually spend more on Quality Assurance & Control than we do on Marketing and Advertising combined. What good is a lab without qualified people? NOW® employs an expert team of highly qualified scientists and technicians, including four Ph.D.’s. They’re constantly working to develop new and improved analytical methods, and their efforts contribute not only to our product quality but that of the entire industry as well.
This is all great, you say, but what about your facility and the equipment you use to manufacture products? Our 203,000 square foot facility is designed and built to standards that exceed food-packaging guidelines. It supports pharmaceutical-grade operations, which greatly enhances our ability to produce the highest quality products quickly. All this means fresher, more effective products on store shelves for consumers. NOW® Foods is an ‘A’ rated GMP-certified manufacturer, one of the first companies in the industry to attain GMP (Good Manufacturing Practices) certification. We’re also certified by QAI (Quality Assurance International) as an organic manufacturer. As consumers become increasingly demanding of supplement quality and safety, NOW® is ready to meet this demand with sound science and state-of-the-art research, manufacturing, and packaging capabilities. We are certain that our efforts to consistently maintain the highest product quality will help make your natural product purchasing decisions easier.
Phosphatidyl Serine - HEALTHY COGNITION BRAIN FUNCTION
December 21, 2005 11:04 AM
“To the dull mind, nature is leaden. To the illumined mind, the whole world burns and sparkles with light.” Ralph Waldo Emerson
From the moment we rise to the moment we rest, our brain is in a decision-making frenzy. When we’re thirsty, our brain tells us that we need water. When we’re hungry, it reminds us that we have a refrigerator full of food. When we’re tired, it lets us know that we need to sleep, and so on. But despite the thousands of decisions we make everyday, our brain still hasn’t figured out a way to let us know what it needs to func¬tion.
Though ironic, this raises a very serious issue. The human brain, like every other organ in the body, demands nutrition - period. Unfortunately, it leaves that up to us to figure out. Thanks to notable advance¬ments in research, we’re finally learning which nutri¬ents are most important for optimal brain function. Phosphatidyl Serine (PS) is a perfect example. This naturally occurring phospholipid has been the subject of numerous studies regarding its ability to boost cognitive function and delay (or potentially reverse) memory deterioration, and suggests that PS may be able to increase the effectiveness of neural transmissions. Interestingly, PS accounts for roughly 15% of the brain’s phospholipid supply. This is enor¬mous because phospholipids play a significant role in the billions of neurotransmissions that take place every second. Yes, billions.
Brain cells are constantly communicating with one another, and send astonishing amounts of impulses throughout the nervous system. This is accomplished via neurotransmitters - chemical messengers that send and receive impulses over the synapses of the brain and throughout the body. Mentally, we’re function¬ing at our best when these cells are well nourished. We can think more clearly, recall memories with ease and operate with greater efficiency. However, a de¬ficiency in neural-nutrients can prevent these mind messengers from functioning as they should. For¬tunately, PS has the ability to cross the blood-brain barrier to deliver critical nutrients and remove mind-slowing waste.
Consider this. The brain functions in the same man¬ner that a major airport does around the holidays. There are millions of actions taking place. Impulses departing, nutrients arriving, endless communication, the occasional problem and more reactions than any¬one could possibly count. There’s confusion, delay and emotion, not to mention the endless series of transmissions that take place every second. Imagine PS as that ultra-motivated employee who shows up to work everyday anxious to expedite everything in sight. It helps neural travelers get to and from their respec¬tive gates, ensures that they have everything they need, simplifies processes that could result in breakdown, and clears isles that are cluttered with junk. Simply stated, PS is the brain’s overachieving go-getter.
PS can help us think more clearly.
It’s 3:06 in the afternoon and you’re scrambling to get to a meeting that you’re already late for. That fluster could be the result of poor neurotransmission caused by a deficiency in essential nutrients like PS. Moreover, these innocent brain-bursts can exhaust our PS reserves, leaving us somewhere hovering be¬tween frantic and sluggish. Every impulse, thought, action, reaction, movement, emotion and desire is the end result of neurotransmitters in action. PS is a major supporter of these actions. Therefore, as we increase the amount of PS in our system, we gain the ability to think and act with greater ease.
PS can reduce the adverse impacts of stress on our body and mind.
What do we do when we’re down in the dumps? While plopping down on the sofa with a snack might be an easy solution, it comes with a price. Not only does stress interfere with mood, but it can also inspire inactivity, over-eating and sluggishness. This is due largely in part to cortisol - a catabolic hormone released by the adrenal glands in response to emotional stress. Studies done to determine the effectiveness of PS on cortisol suppression have shown that it works by suppressing the hormones that produce cortisol. As a result, supplementing with PS may be able to help reduce the amount of stress related hormones that ultimately leave us singing the blues.
PS can expedite post workout recovery time.
Endurance athletes who carefully monitor their body’s response levels are increasingly turning to PS. Immediately following strenuous activity, the body responds by releasing adrenocorticotropin (ACTH) – a hormone that discourages testosterone and encourages cortisol. By limiting ACTH pro¬duction, PS reduces the amount of muscle tissue breakdown that occurs during exercise. A common misconception is that muscles grow during exercise - wrong. In fact, muscles are torn down during ex¬ercise and grow in-between workouts – hence the term recovery. During recovery, PS helps prevent the activity of growth-inhibiting hormones. This helps athletes recover faster so their gains are realized more quickly.
In short, Phosphatidyl Serine appears to be a completely safe and beneficial dietary supple¬ment that can offer a wide range of physical and mental health benefits. NOW® Phosphatidyl Serine is derived from soy leci¬thin, and includes Choline and Inositol – two metabolites that work synergistically to help in¬crease circulation and cognitive response.
December 19, 2005 09:19 AM
Phosphatidyl Serine - As we age, our natural production of Phosphatidyl Serine (PS) slows. As a result, our ability to learn, concentrate and recall memories inevitably declines. This multi-tasking phospholipid is a major component of neural membranes, and aids in the transition of impulses as well as the absorption of cognitive nutrients. PS has also been shown to inhibit the secretion of cortisol, a hormone often found elevated in individuals who are frequently stressed and depressed.*
ALPHA GPC - Improves Mental Performance
June 28, 2005 06:21 PM
The quality of our life experience—and our ability to live life to the fullest—is a direct result of optimal brain function. Only a few years ago, nothing could be done to stem the tide of poor circulation, forgetfulness and “mental fog.” But neurological science exploration has identified a fundamental brain compound critical to attention, learning, memory, and even the higher cognitive functions of reasoning and intuition. Research confirms that L-alpha-glycerylphosphorylcholine (called Alpha-GPC for convenience) is crucial to neuronal function and structure. Derived from purified soy lecithin, Source Naturals ALPHA-GPC readily converts to acetylcholine in the brain, helping to maintain neuronal structure integrity. Source Naturals provides an easy and convenient means to profoundly impact the very nexus of our body and mind.
GPC Is Unique
No other nutritional compound comes close to GPC in its ability to boost critically important acetylcholine levels. Found in both the brain and the peripheral nervous system (including the nerve-muscle junctions), acetylcholine is a key nerve messenger molecule, or neurotransmitter. Aging brains are characterized by functional deficiencies in both acetylcholine and its cholinergic receptors. GPC is a highly bioavailable supplement that boosts acetylcholine levels to improve cognitive function. It is also a major choline reservoir, helping to protect the brain against damage from poor circulation and potentially toxic metabolites.
Deficiencies in acetylcholine can cause the body to break down phosphatidylcholine for its choline content, leading to the death of brain cells. Yet in controlled clinical trials of middle-aged subjects taking GPC, reaction time was enhanced and there was improved energy generation and electrical coordination in the brain. For older subjects, double-blind trials demonstrated that GPC had superior benefits over certain other brain nutrients for mental focus, recall, verbal fluency—a unique, marked overall enhancement of mental performance. GPC is an example of what the great Linus Pauling referred to as “orthomolecules,” that is, molecules that are “orthodox” or “correct” for the body. GPC excels as a protective nutraceutical for memory loss and mood enhancement. It protects cells of the brain (and other organs) from damage, shielding a range of important biomolecules against toxin build-up.
Extensive Clinical Testing
In clinical trials that involved more than 5,000 patients, GPC showed marked improvement in overall brain performance. Depending on the particular trial, 50-70 percent of the patients who received GPC had their mental functions improved to a degree “meaningful to life quality.” GPC has shown revitalizing effects on the declining brain, and preliminary evidence suggests GPC may act on the pituitary gland to partially restore its capacity to make vital for cell maintenance and longevity. Other unique brain features of GPC are its benefits for attention and recall in young healthy adults, and its superior bioavailability. GPC readily crosses the bloodbrain barrier to raise brain choline levels within a few hours following oral intake. GPC helps with body-mind integration by being a ready reservoir for acetylcholine. This neurotransmitter is ubiquitous in brain circuit maturation, expansion, renewal and repair, as well as in the “agility” or adjustments of the circuitry that occur during adult life. In addition, an animal study has shown that GPC increases the release of GABA (gamma-aminobutyric acid), the most important and abundant inhibitory neurotransmitter in the brain. It acts as a “balancer” for the brain and helps induce relaxation and sleep. Without sufficient GABA, neurons fire at random, unable to make sense of incoming signals. GABA helps minimize “neural noise,” making it easier to focus and concentrate.
Why you should take GPC:
Increased Brain Power and Memory with Ginkgo
June 25, 2005 11:23 AM
Increased Brain Power and Memory with Ginkgo
Ginkgo’s ability to enhance cognitive function is becoming common knowledge. Boosting the capability of the brain to record information, communicate ideas or recall concepts can all be enhanced by taking ginkgo biloba therapeutically. Evidently, providing a better oxygen supply to brain cells is ginkgo’s primary neural action. The brain is the body’s most sensitive organ to oxygen deprivation. Today, more than ever, the effects of smoking, alcohol and stress in general can diminish brain function and compromise mental alertness. Ginkgo has demonstrated over and over that it can make a significant difference in memory retrieval, fact retention and problem solving.
One of the most impressive aspects of ginkgo is its ability to stimulate circulation and oxygen flow to neural tissue, there by improving cognitive functions and memory. In test cases when ginkgo has been administered, an increase in cerebro-circulation has been noted in both healthy or diseased brain tissue. What makes this finding particularly relevant is that other circulatory enhancers, whether natural or synthetic do not usually possess this capability.
In addition, ginkgo increases oxygen transport at the blood-brain barrier site, while inhibiting the permeability of toxins into brain tissue. As well as boosting blood supply to the brain, ginkgo has demonstrated the ability to increase the rate at which information is transmitted at the nerve cell level.2
In a double-blind study, one group of healthy young women received ginkgo extract, and the other was given a placebo. A memory test was administered and the reaction time in those women who had taken the ginkgo improved significantly. These findings corresponded with EEG tracings which showed increased brain wave activity.3
Short-term memory and basic learning rates can be statistically improved by using ginkgo. Ginkgo’s ability to enhance memory may also be helpful for epileptics who take anticonvulsants. Typically, an anticonvulsant can impair memory function, making it difficult to retrieve names or numbers from memory banks. In addition, although research is lacking, because ginkgo stimulates brain function, it may help to inhibit improper discharging of electrical impulses which is the primary cause of seizures in epileptics. Ginkgo is rapidly gaining an impressive reputation as a brain enhancer. It has demonstrated its capability to improve memory, mental efficiency and the ability to concentrate. It has also been shown to reduce anxiety, headaches, tension, vertigo, and age-related cerebral disorders. Anyone who has suffered a stroke should look into the possible benefits of ginkgo to amplify mental function and clarity.
Considerable research on ginkgo conducted in Eu rope has confirmed that ginkgo does indeed facilitate better arterial circulation as well as improve electrical transmission in the nerves. The latter function also contributes to improved oxygenation and nutrition to the brain.4 Ginkgo is now accepted as a brain booster which improves memory, mental efficiency, cognitive function, communication, orientation and the ability to concentrate. Recently, the notion of using ginkgo for learning disorders has received some attention. Forthcoming research on the subject will help to clarify its potential for treating such conditions.
Fats and Oils: Clearing the Confusion
June 21, 2005 05:31 PM
Fats and Oils: Clearing the Confusion
By Fred Pescatore, M.D.
Aside from tax forms, it's hard to find anything more confusing to consumers than fats and oils. Fat-free diehards still don't know that fat is essential for the brain, hormones, cellular membranes: life itself. The clueless still use shortening, margarine and damaged grocery store vegetable oils. But what worries me more is that supposedly educated consumers aren't even getting it right. Should we be surprised since their doctors probably don't know the truth?
Mistakes made by your customers. They:
Let's clear up these myths so consumers can get busy being confused about something else:
I hope this helps you educate consumers about the proper use of fats. Unfortunately, that still leaves a long list of other things they've been misled about.
Scents of Balance
June 14, 2005 11:54 AM
Scents of Balance by Rosemary Sage Energy Times, January 5, 2005
Life can feel like an emotional rollercoaster, with the high-stress jitters following the low-mood blues. But aromatherapy-the healing power of scent-can restore equilibrium.
The use of volatile plant oils, including essential oils, for psychological and physical well-being dates back thousands of years. The ancient Chinese, Egyptians, Greeks and Romans used infused oils and herbal preparations for medicinal, fragrant, cosmetic, even spiritual reasons.
During the late 20th century, people started to relearn the benefits of aromatherapy and these days, aromatherapy's reputation as a soothing, healing art continues to grow. Once you've experienced the odiferous power of aromatherapy's essential oils, you'll keep coming back for more: These gently wafting odors have the power to stimulate or calm, invigorate or relax.
When you enter this scented world, "there you will find nature in one of its most powerful forms-aromatic liquid substances known as 'essential oils,'" says Valerie Ann Worwood in The Complete Book of Essential Oils and Aromatherapy (Thorsons). Essential oils form what Worwood refers to as the "fragrant pharmacy," a collection of concentrated substances used in pharmaceuticals, foods and cosmetics.
When you sniff the aromas of essential oils, "they enter and leave the body with great efficiency, leaving no toxins behind," Worwood points out. "The most effective way to use essential oils is...by external application or inhalation. The methods used include body oils, compresses, cosmetic lotions, baths-including sitz, hand and foot baths-hair rinses...perfumes...and a whole range of room [scenting] methods."
As Worwood explains, essential oils are produced in various parts of different plants. As a result, it takes a great deal of specialized work to extract essential oils. About 60,000 rose blossoms are consumed in the production of an ounce (!) of rose oil.
Just as the antioxidant phytonutrients we eat in vegetarian foods link our bodies to the health-promoting chemistry of plants, the penetrating nature of essential oils are thought to connect our souls to the essences of flora. "From inside comes the voice and from inside comes the scent," observed the 19th century German doctor Gustav Fechner, quoted by Robert Tisserand in The Art of Aromatherapy (Healing Arts Press). "Just as one can tell human beings in the dark from the tone of voice, so, in the dark, every flower can be recognized by its scent. Each carries the soul of its progenitor."
Fechner believed that the power of essential oils to stir our deepest emotions derives from their function as a vital means of communication in the plant world. As Tisserand asks, can't we imagine that flowers "communicate with each other by the very perfumes they exude, becoming aware of each other's presence?"
The Science Behind the Scent
While alternative medical practitioners have acknowledged the effectiveness of aromatherapy for thousands of years, only recently have conventional medical researchers begun seriously looking into how this technique works.
For instance, a study of estragole, a chemical found in basil, fennel and tarragon, determined that it could potentially ease back pain by inhibiting inflammation of the sciatic nerve. (The sciatic nerve, the longest nerve in the body, runs from the back down the leg.) The researchers discovered that estragole is "active on nerves," a conclusion that aromatherapy practitioners, who employ the scent of these oils to soothe pain, already knew. Science is verifying another piece of information long known to practitioners-that while certain essential oils can calm you down, others prod your alertness. In a study performed at the University of Northumbria in England, scientists found that sniffing the scent of lavender lulls the human brain into a comfortable, rather stupefied state, while rosemary, in contrast, can sharpen recall.
As the English researchers noted, lavender "produced a significant decrement in performance of working memory, and impaired reaction times for both memory and attention-based tasks." That's probably why the odor of lavender is noted for enhancing sleep. On the other hand, the scientists found that rosemary "produced a significant enhancement of performance for overall quality of memory and secondary memory factors." However, they did point out that under the influence of both of these oils, performance slowed when tackling a battery of memory tests. Apparently, the oils mellowed people so that they had little motivation to rush through the paperwork.
As Frazesca Watson notes in Aromatherapy Blends & Remedies (Thorsons): "The aroma of the oils directly affects our moods and emotions and sometimes our short- and long-term memory. Together with a wide range of physiological benefits, the aroma can help with emotional upsets such as depression, anxiety, nervous tension, anger, apathy, confusion, indecision, fear, grief, hypersensitivity, impatience, irritability, panic and hysteria."
Essential oils are especially helpful at defusing stress. Watson notes, "Treatments with essential oils are therefore very helpful for all sorts of stress-related problems, so common in our modern life."
As scientific research into the effects of these oils continue, conventional medical practitioners are sure to embrace them in increasing numbers. But before there were scientists around to confirm the effects of these wonderful scents, the ancient medical practitioners in Egypt and Greece attributed the origins of aromatherapy to the gods. For many people in today's overstressed world, the relaxing assurance of essential oils certainly seems heaven-s(c)ent.
Best Bread ...
June 13, 2005 07:30 PM
Best Breads by Jane Lane Energy Times, December 9, 1999
Few of us can resist the seductions of freshly baked bread, warm and fragrant, poised on the edge of a steaming bowl of soup or painted with an aromatic swath of rosemary scented oil. Even those of us from the most culinary challenged households can recall the pleasures of the simple plump white dinner roll or flaky biscuit piled in a basket on the dinner table.
Bread has blossomed from sideshow status beside the dinner plate to a full-scale mealtime headliner, a scrumptious star enriched by nutritious grains, herbs, fruits and vegetables.
Contemporary cooks build meals around crunchy cornbread or chewy focaccia, presenting soups or salads as satisfying counterpoints. Want to jump into the bread baking basket or hone your skills? Two top vegetarian chefs shared with Energy Times their passion for bread and their expertise in baking. See if you don't find that ardor contagious.
Nancy Lazarus is a chef at the famed Moosewood Restaurant in Ithaca, New York, established in 1973 to serve up natural fare with a homecooked, vegetarian emphasis. The bill of fare changes daily at Moosewood, but there's one constant: a cup or bowl of soup, a salad and a thick slice of bread. Some loyal customers have ordered the daily special for 20 years.
That's why bread occupies a cherished spot at Moosewood. Nancy Lazarus tells why and offers some of Moosewood's favorite bread recipes: "Cooking is like art; baking is like science; bread is like magic. No matter how much science you apply, you'll never have complete control: It'll do its own thing on some level, which is part of its charm, if you're charmed by that sort of thing. Breads come out differently depending on heat and humidity, the heat of the oven; yeast is a variable that can be slower or faster acting.
"There are bread machines, of course, and they work. But they're not as satisfying as the real thing, the kneading, which can be almost therapeutic, and the control over the ingredients to your own specifications.
"Bread is not that difficult. Know your own oven, to begin: Good insulation is important and how the heat travels around inside. Convection ovens are a wonderful thing.
"There are difficult breads we recommend you buy at a good bakery: baguettes, Italian, French and Cuban that are crusty outside and soft inside.
"But focaccia is easy. It's a yeasted bread that's better to make at home than buy because it's so fresh and you can control the toppings. It only requires one slow and one quick rising but you have to be there for a while.
"Then there are quick breads that use baking soda or powder, like cornbread. If you want a good meal at home and can make only one thing, make a quick bread. They're satisfying and delicious warm from the oven; and the aroma of bread fills the house. A corn bread with tomato soup for supper is a nurturing meal good for vegans.
"Popovers are fast and simple, a middle American 50s treat, but you do need a hot oven and 45 minutes. Also easy to make: sweet breads- carrot, banana, zucchini-and biscuits.
"To reduce the fat in denser quickbreads and cakes, use applesauce. It gives body and moistness.
"The number of wheat-sensitive people is rising dramatically. A theory I think makes sense is that in the last 30 years the varieties of wheat grown has been reduced to 1 or 2 that are more easily cultivated and harvested with the machinery available. People are overloaded with one type of wheat.
"Gluten is the offending substance in wheat and some oats; try rice, tapioca and potato flours, which are denser and more fine and don't produce a good crust. Improve the crust by baking in a preheated cast iron skillet.
"Also investigate chickpea flour. You don't make a loaf of bread with it- use it for flatbreads like papadam, which is in Indian cookbooks. And it's good for batter for vegetables.
"Spelt is the closest to wheat flour in consistency but some people can be sensitive to it.
"Visit a natural food store to check out the flours. The mills sometimes print handouts with recipes and a lot of those are real good, especially for what works with their flour. Or you may run into a baker who will whet your appetite with ideas and recipes.
"Bread is the supreme comfort food. It can speak to us, and reassure us. The magic of bread and how it varies: There's something appealing in that. In today's world, food is predictable, and that's reassuring to some people. At Moosewood, things are always different, and that's good."
Claire Criscuolo puts an intensely personal spin on the eclectically ethnic style of cooking at her esteemed vegetarian restaurant, Claire's Corner Copia. That 25-year-old institution in New Haven, Connecticut, reflects her zest for the freshest ingredients, robust flavors and inspired combinations. Claire, a teacher and advocate for healthful cuisine, pours her passion into her breadmaking as well:
"Healthy bread is like anything else-it has healthy ingredients. We use the best organic unbleached flour and yeast, pure vanilla, whole eggs (not dried and powdered), whole milk and organic sour cream. You want to use good, fresh ingredients. It's the essence of healthy cooking. "I tell my staff, 'Don't use your soup pot as a garbage pail. Bread is the same. If the ingredients aren't at their freshest for serving, then they aren't right for other uses in the kitchen.
"Our bread is very important at Claire's. We make a country white and a honey wheat in a pinwheel loaf-400 a day-and challah for the morning French toast with sauteed bananas or as buns for veggie burgers. "It's not practical to bake bread every day. We let our bread rise several times, punching it down again and again. For the home cook, it's time consuming. Even I'm happy to buy a good loaf of bread. "But anybody can bake bread. Combine flour, water and yeast and watch it grow! It's delights all your senses. And it a gratifies and satisfies. I was kneading it all by hand until we got up to 12 loaves a day.
"I love a good oatmeal molasses bread; a whole wheat bread with walnuts, rosemary and finely chopped sweet onion sauteed in olive oil for a roasted vegetable sandwich; or an anadama bread with split pea soup.
"Bread is part of a meal. It requires time and effort, but I can't think of many things worthwhile that don't."
Herbs in Perspective
June 10, 2005 10:25 PM
Herbs in Perspective by Phyllis D. Light, RH-AHG Energy Times, June 16, 2004
"I don't claim a cure...I just try to give people some ease," noted Tommie Bass, a traditional Southern herbalist whose life has been the topic of several books, including Mountain Medicine by Darryl Patton (Natural Reader Press) and Trying to Give Ease by John Crellin and Jane Philpott (Duke University Press). That philosophy reflects the perspective embraced by herbalists for eons.
The traditional use of herbs is incorporated into all cultures. Herbs were the first medicine and the origin of what we now call modern medicine. These plants have not been prescribed to conquer specific illnesses but instead nourish the body and aid in building overall health.
Observation, psychological need and human instinct form the foundation of traditional herbal knowledge and use. This knowledge has been passed down through generations based on practice and experience. The result: a depth of information about the safe and effective use of herbs that spans thousands of years.
The goal of a traditional herbalist is to bring the body into balance (homeostasis), prevent disease and support immune functioning. Unfortunately, any kind of therapeutic knowledge can be misused, and that has happened with some herbs, causing some people to question herbal medicine's safety.
As more people turn to natural therapies, scientists have begun to perform evidence-based research into their safe and effective use. The good news is that much of this research has validated the effectiveness of herbs and supplements.
Echinacea to the Rescue
Do the sniffling sneezes that herald a cold have you reaching for your bottle of echinacea? If so, you are in good company. Echinacea (Echinacea spp) is one of the top-selling herbs.
The colorful American prairie plant was extremely popular during the early 1900s, until the use of modern antibiotics relegated it to the back shelf. But a resurgence of interest in herbs propelled echinacea back into the mainstream in the second half of the twentieth century. And this herb boasts an impressive body of research and has an excellent record of safety.
For instance, researchers at Virginia Commonwealth University School of Pharmacy have found echinacea to be effective in supporting the body's defenses against upper respiratory tract infections and for reducing the duration of discomforts that accompany the common cold (Pharmacotherapy 2000; 20(6):690-7).
Although studies have not confirmed its ability to prevent colds, echinacea is widely used by many folks for just that purpose. Researchers have found that echinacea's effectiveness may drop if you use it for eight straight weeks (Am J Health-Syst Pharm 1999; 56(2):121-2). So if you take it for a couple of months, take a couple of weeks off before using it again.
St. John's wort is another herb with ancient origins that has experienced a modern resurgence. Named after St. John the Baptist, St. John's wort (Hypericum perforatum) is generally in bright yellow bloom around St. John's Day (June 26). According to herbalist Michael Tierra, author of The Way of Herbs (Pocket Books), St. John's wort affects the liver and the nervous system. In 1984, the German Commission E, a recognized herbal authority, approved St. John's for depressive disorders, and in topical form for acute injuries and first-degree burns.
Modern research has reaffirmed the use of St. John's wort in the short-term treatment of mild to moderate depression (Cochrane Review Issue 2, 2004). It has also been found to be useful in premenstrual depression (Int J Psy Med 2003; 33(3):295-7). (Researchers have found that the herb may alter how the body processes some prescription medications, so check with your healthcare provider before using such medicines along with St. John's wort.)
King of Herbs
" Ginseng (Panax) received the lofty title, King of Herbs, due to its reputation as a tonic and its ability to stimulate the body into healing," notes herbalism writer Darryl Patton. This plant was once so popular in China that it was worth its weight in gold.
In fact, ginseng is the popular name for two different types of ginseng, American and Korean (Panax quinquefolium and P. ginseng). Both are considered adaptogens, or substances that help the body deal with stress more effectively. And modern research has found that ginseng can be used to improve overall energy and vitality, and to help the body deal more effectively with chronic stress (J Pharm Sci 2003 Dec: 93(4):458-64).
Researchers have found that ginseng helps boost the immune system (J Med Food 2004 Spring; 7(1):1-6). This ancient herb is also a powerful antioxidant that confers protection on the heart (Biochem Biophys Acta 2004 Feb 24; 1670(3):165-71). In other studies, ginseng has been found to reduce symptoms of menopause, improve endurance and lower blood sugar levels. To avoid overharvesting wild ginseng, most of the herb on the market is now grown on farms.
Ode to Ginkgo
Known as the Living Fossil, ginkgo is the oldest known plant in the world. A native of Asia, ginkgo (Ginkgo biloba) is now found in many US cities, where it has been planted as a quick-growing shade tree. Traditionally, ginkgo was used for disorders and diseases of the lungs and the kidneys, as a remedy for bronchitis and to improve circulation in older people.
Ginkgo contains substances that act as potent antioxidants by scavenging cell-damaging free radicals, and it is thought to help reduce the risk of disease. By opening capillaries, ginkgo increases circulation, and enables nutrients and oxygen to move around the body, especially to the extremities.
Indeed, recent research indicates that ginkgo may ease pain associated with arterial disease in the legs (Am J Med 2000; 108:276-81). Other studies support the use of ginkgo for acute stress (J Pharm Sci 2003 Dec; 93(4):458-64) and some cases of hearing loss (Acta Otolaryngol 2001; 121:579-84).
In a UCLA Neuropsychiatric Institute study on ginkgo, researchers found significant improvement in the verbal recall of people who had age-related memory problems. According to Dr. Linda Ercoli, lead author of the study, "Our findings suggest intriguing avenues for future study...with a larger sample to better measure and understand the impact of ginkgo on brain metabolism."
Traditionally, fiery ginger (Zingiber officinale) has been used to aid digestion, reduce nausea, relieve gas, reduce symptoms of arthritis and strengthen the heart. Modern researchers have started to validate these traditional uses; ginger has reduced the nausea and vomiting of morning sickness in studies (Aust NZJ Obstet Gynaecol 2003 Apr; 4392:139-44).
Meanwhile, researchers at the University of Minnesota have applied for a patent on a substance found in ginger, believing it to have anticancer activity. According to Ann Bode, "Plants of the ginger family have been credited with therapeutic and preventive powers and have been reported to have anticancer activity."
Ginger can be found in natural food stores as fresh or dried root. It often appears in small amounts in herbal formulas as a carrier herb-one that helps move other herbs around the body.
The best medicine combines the health support of herbs with the scientific rigor of conventional medicine. And as scientists continue to search for new medicine from ancient remedies, we can enjoy the best of both perspectives.
Higher Mind - Smart Nutrients for the Performance of a Lifetime...
June 02, 2005 12:18 PM
Our adult years are the time to reap the fruit of an active, meaningful life – appreciated by family and friends who value our experience and knowledge. For some, however, their later years are clouded by a mental decline that erodes their capacity to enjoy life. More of us are becoming apprehensive about the future health of our minds. Will we still be able to communicate our needs as well as our wisdom? As science focuses its investigative might on the workings of the human brain, new findings suggest that it is possible to enjoy a vital, healthy brain and mind – well into old age. Based on compelling research, Source Naturals formulated HIGHER MIND. It contains the most important Neuroceuticals™ now recognized by nutrition scientists – including phosphatidyl serine, a natural nutrient that promotes cognitive function. The connection is clear: nourish your brain; enrich your life.
To have a healthy, well-functioning brain and nervous system, we need the correct nutrients. Our diets must provide the necessary raw materials for nerve cells to grow, for the synthesis of neurochemicals, and for the maintenance of nerve cell membranes. Nutritional deficiencies can alter the brain’s metabolism, which is expressed by changes in perception and thinking, behavior and mood.
Brain Cells – Issued at Birth
Before birth, neurons (nerve cells) are created at the amazing rate of 15 million per hour. As infants, we have over 100 billion neurons, but this is the most we will ever have because – unlike most other cells in our body – nerve cells do not reproduce. A different strategy is used to replace the neurons that are naturally lost throughout life: nerve cells repair themselves and grow by extending branches of nerve fibers called dendrites (from the Latin word for tree). These are the communication links with other neurons that form the circuitry of the brain. A single neuron may be in contact with up to a hundred thousand others! When the density of this fragile organic communication network decreases, we experience a corresponding decline in mental acuity.
Brain Cell Membranes
The membrane is the working surface of a cell. It needs to be strong yet flexible, so the cell can maintain its integrity and be able to move and change shape. The membrane regulates the flow of nutrients into the cell and the removal of waste, plus controls the passage of molecular messages from outside the cell to its interior. Membrane ion pumps use a third of the cell’s energy just to maintain the correct ratio of sodium to potassium. In neurons, a rapid exchange of sodium and potassium ions across the nerve membrane is responsible for their unique ability to generate the electrical impulses that are the basis of all communication in the nervous system. As cells age, their membranes become less fluid and more rigid. Key membrane molecules called phospholipids are crucial to the health of neuron membranes, allowing the brain to maintain its youthful quality. The phospholipids in HIGHER MIND – especially phosphatidyl serine and phosphatidyl choline – are essential nutritional supplements for the aging brain.
Phosphatidyl Serine – Key to Cognition
For the past decade, researchers have been investigating the role in brain health of a remarkable neuroceutical, phosphatidyl serine (PS). This key structural molecule is integral to the matrix of fats and proteins that compose cell membranes. Although PS is found in all the cells of the body, its highest concentration is in nerve cell membranes. PS is rarely found in the foods we eat, so the body has to synthesize it, but the process is energy- intensive and becomes less efficient with age. Consequently, our levels of PS tend to decline as we get older. PS taken as a dietary supplement is well-absorbed, readily reaching the brain, where it helps create more effective, well-structured nerve cell membranes. The positive effects of PS supplementation have been demonstrated by 23 clinical studies with over 1200 human subjects, ages 43 to 90. Consistent and statistically significant results have confirmed the value of PS in improving age-related cognitive decline, as well as in improving behavioral aspects such as apathy and withdrawal.1 A major study concluded that for one particular measurable parameter of higher mental functions, PS recipients achieved scores of persons roughly 12 years younger.2 Nerve Growth Factor (NGF) is one of the most important proteins the body makes. It enables neurons to extend dendrites out to other neurons, allowing the brain to maintain an effective communication network. In experiments, PS enhanced the production and reception of NGF, which tend to drop off radically with age.3 The effects of PS at the cellular level are manifest in the performance of the brain as a whole. Subjects taking PS showed increased levels of brain energy metabolism. This enhancement corresponded to higher performances on cognitive tests.4
The Chemistry of Thought
Science now understands the role of neurotransmitters in regulating the body’s complex network of behavior. Neurotransmitters are the chemicals used by neurons to communicate with each other. Activated by a neuron’s electrical impulse, neurotransmitters travel between nerve cells, where they excite or inhibit (in various degrees) the electrical impulse in neighboring cells. One of HIGHER MIND’S key strategies is to improve the brain’s ability to produce and use acetylcholine, a key excitatory neurotransmitter. Acetylcholine is essential for both the storage and recall of memory, and partly responsible for concentration and focus. It also plays a significant role in muscular coordination. Patients showing cognitive decline may exhibit reduced ability to synthesize and utilize acetylcholine.5 The chemical building blocks of acetylcholine and other neurotransmitters are called precursors. The most important one for acetylcholine is DMAE (dimethylaminoethanol). This natural substance is found in various fish, such as anchovies and sardines. Supplements of DMAE (and phosphatidyl choline) promote increased levels of choline in the brain. Acetylcholine is created when an acetyl group is attached to the choline molecule, with the help of choline acetyl transferase (CAT), a key brain enzyme. Acetyl L-carnitine is an amino acid that activates this enzyme. Acetyl L-carnitine may also help reduce lipofuscin deposits in the brain because of its involvement in the metabolism of fatty acids.6 Lipofuscin is composed of oxidized fats and proteins; the brown “age spots” on the back of an elderly person’s hand are made of lipofuscin. The amino acid L-pyroglutamic acid sensitizes the acetylcholine receptor sites on a neuron membrane. A given amount of acetylcholine will then have a larger, more powerful effect. Studies have shown that supplements of L-pyroglutamic acid seem to enhance the ability to focus, remember, and learn.
Total Nutrition for the Brain
The neurotransmitters dopamine and noradrenalin are critical to motor coordination, motivation, concentration, and alertness. Like acetylcholine, their production tends to decline with age. The precursors and activators of dopamine and noradrenalin included in HIGHER MIND are the amino acids N-Acetyl L-Tyrosine and DL-phenylalanine (DLPA), plus folic acid, vitamins B-3, B-6, and C. DLPA is also a precursor to PEA, a neuroamine that has a stimulating effect on the brain. Glutamine is an amino acid precursor to glutamic acid, a major excitatory neurotransmitter involved in mental activity and learning. Glutamine acts as an alternative fuel source for the brain when blood sugar levels are low. It also helps the brain dispose of waste ammonia, which is a natural result of protein breakdown but is irritating to neurons even at low levels. GABA is a dietary amino acid which is also an inhibitory neurotransmitter. GABA works to calm and balance the mind, enhancing mental focus. Along with taurine, these two relaxing neurotransmitters provide a balancing influence to the other, excitatory neurotransmitters. Taurine is found in brain tissue more than anywhere else in the body. It has antioxidant properties and serves as a nerve cell membrane stabilizer, preventing excessive or erratic electrical activity in the brain.
The Importance of Magnesium
Magnesium must be present in adequate amounts in the synaptic gaps between neurons or the neurons become hyper-reactive: causing noises to sound excessively loud and emotional reactions to be extreme. Magnesium also activates a key enzyme responsible for maintaining cellular sodium- potassium balance, which is absolutely essential to the electrical activity of nerve cells, as well as to the existence of the cell itself. (Cells would burst if the sodium-potassium ratio were wrong.) Magnesium also helps relax cerebral blood vessels and is important to the manufacture of ATP, the chief energy molecule of the brain. A buildup of aluminum has been found in the brains of some elderly. In 1989, the British medical journal Lancet published a study showing that drinking water with aluminum can increase the risk of damage by up to 50%. An abundant natural element, aluminum is now a common feature in our culture. It’s found in tap water, cookware, deodorants, beverage containers, baked goods, and of course as aluminum foil. In the brain, aluminum breaks down the structure of neurons – causing them to starve – by displacing magnesium from tubulin, a glycoprotein responsible for making microtubules. These tiny pipe-like structures within a neuron provide needed rigidity, as well as transport nutrients from the nucleus down the dendrites to the ends of the nerve cell. Magnesium malate is an excellent form of magnesium that ensures neurons receive this vital mineral.
B is for Brain Vitamins
HIGHER MIND also contains a high profile of B vitamins and other key nutrients that are often N A T U R A L S S O U R C E Strategies for Wellness SM ¤ lacking in older individuals. A deficiency in any of the B vitamins can alter nerve function and psychological well-being. Thiamine (B-1), known as the “nerve vitamin,” was first recognized because its deficiency caused beriberi, a degenerative nerve disease. Thiamine is part of the structure of nerve cell membranes and is important to the reparative process that neurons need to offset the stress of continual firing of the electrical impulse. Low amounts of thiamine can cause cell malnutrition in the hypothalamus, the brain’s memory center. 7 NAD and NADH, two coenzyme forms of Niacin (B-3), are the most plentiful coenzymes in the brain. They are essential to hundreds of enzymatic reactions, including ones that produce energy. NADH can stimulate the synthesis of key mood-elevating neurotransmitters. It is also one of the body’s most potent antioxidants. Pantothenic acid (B-5), cyanocobalamin (B-12), and folic acid are required to form the myelin sheath – the insulating covering of nerve fibers. A diet low in pantothenic acid has been shown to make test subjects emotionally upset, irritable, and depressed.7 A lack of B-12 can result in poor concentration and, in severe deficiencies, hallucinations. Pyridoxine (B-6) is precursor to over 60 enzymatic reactions and is involved in the synthesis of several neurotransmitters.
Brain cells almost exclusively burn glucose for their energy (other cells can also burn fat), and typically require 50% of all the glucose in the blood. Two B-like vitamins help in the utilization of glucose: PAK (pyridoxine alpha-ketoglutarate) may potentiate the effects of insulin and improve glucose utilization to the cells;8 Biotin is important for the transformation of glucose into energy in the brain. Lipoic acid and coenzyme Q10 are metabolic energizers that help produce ATP, the primary energy molecule in the body. Since the brain uses 20% of the body’s total energy supply, efficient ATP production is vital. Lipoic acid and CoQ10 are also powerful antioxidants that help regenerate other antioxidants in the body. The blood vessels feeding the brain become less efficient as we pass middle age. Since the brain depends on the bloodstream to deliver nutrients and oxygen and to remove waste, the quality of this blood flow is paramount to proper brain nutrition. Ginkgo biloba leaf extract has been shown in scientific studies to increase blood flow to the brain by helping vessels to dilate. It also promotes the smoothness and healthy integrity of blood vessel linings.
For the Life of Your Mind Without proper nutrition, the brain will deteriorate; therefore strategies are needed to both enhance current brain function and protect it throughout life. Based on the latest scientific findings, Source Naturals HIGHER MIND is formulated with neuroceuticals that support the mental functions that tend to decline with age. They give your brain the nourishment it needs to integrate perception, memory, and learning into a more comprehensive awareness – so you can excel for a lifetime.
May 31, 2005 04:39 PM
Acetyl-L-carnitine is truly a mind-body nutrient. It helps synthesize acetylcholine, the brain's principal neurotransmitter responsible for learning and memory. And it is a more bioavailable form of L-carnitine, an amino acid derivative that performs the vital function of transporting longchain fatty acids into the cellular mitochondria where they are oxidized to generate metabolic energy. Supplemental acetyl-L-carnitine supports the activity of brain cells that depend on acetylcholine. It can also reduce the metabolic waste products that damage cells over time. As one of the most important nutrients to help slow the aging process, acetyl-L-carnitine is at the heart of Source Naturals' commitment to empower people to take charge of their own health.
Acetylcholine is the brain's principal neurochemical of thought. Neurons need it to communicate with each other, especially to create and recall memories. Acetylcholine is also involved in muscular coordination. At neuromuscular junctions throughout the body, it tells muscles when to contract. But the efficiency of cells that use acetylcholine naturally declines with age, partly because of decreased activity of the enzyme that synthesizes this neurotransmitter.
Acetylcholine is created when the enzyme choline acetyl transferase (CAT) attaches an acetyl group to a choline molecule. CAT activity is heightened by acetyl-L-carnitine, which donates its acetyl group. Acetyl-L-carnitine is made in small amounts naturally in the body, but its production begins to decline in midlife. In well-controlled human studies, supplemental acetyl-L-carnitine slowed the progress of mental decline by notably improving attention and memory. When supplemental acetyl-L-carnitine was combined with lipoic acid (a powerful natural antioxidant), significant improvement in memory was seen in animals. Researchers said that together the two chemicals "tune up" the mitochondria, the energy-producing organelles that power all cells. Mitochondrial decay is believed to be the primary reason for age-related deterioration of cognitive function and energy levels.
Cellular Energy and Protection
As the active form of L-carnitine, acetyl L-carnitine efficiently transports long-chain fatty acids into the mitochondria where they are converted into ATP (adenosine triphosphate), the energy molecule. Animal studies suggest that supplemental acetyl L-carnitine has a positive effect on energy generation as well as on the structural integrity of aging mitochondria. By supporting fatty acid metabolism, acetyl L-carnitine also helps reduce lipofuscin, a metabolic waste product composed of damaged proteins and rancid fats. The brown "liver spots" on some elderly hands are composed of this aging pigment that gradually builds up in cells of the heart, liver, brain, and lens of the eye.
Ninety-five percent of the body's carnitine is found in muscle cells, especially in the heart where mitochondria comprise nearly 50% of a cell's volume. During prolonged exercise, muscles have a high demand for carnitine because fats can account for up to twothirds of the energy burned. L-carnitine supplements can increase exercise endurance and reduce fatigue. Acetyl L-carnitine is also a key nutrient in Source Naturals' legendary neuroceutical formulas MEGAMIND™ and HIGHER MIND™. And because acetyl L-carnitine also generates the basic energy that affects all biological and mental processes, this mind-body nutrient is one of the few nutritional compounds with such a broad range of action in maintaining youthful functioning. Source Naturals ACETYL L-CARNITINE is therefore an essential part of a smart strategy to live well, age well.
Carta A. and M. Calvani. Acetyl-L-carnitine: a drug able to slow the progress of Alzheimer's disease? Ann NY Acad Sci 1991; 640: 228-232. Hagen T.M. et al. August 4, 1998. Acetyl-L-carnitine fed to old rats partially restores mitochondrial function and ambulatory activity. Proc Natl Acad Sci USA 95(16):9562-6. Liu J. et al. February 19, 2002. Age-associated mitochondrial oxidative decay: Improvement of carnitine acetyltransferase substrate-binding affinity and activity in brain by feeding old rats acetyl-L-carnitine and/or R-alpha-lipoic acid. PNAS 99(4):1876-81. Spagnoli A.U. et al. 1991. Long-term acetyl-L-carnitine treatment in Alzheimer’s disease. Neurology. 41(11):1726-1732.