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Is Inflammation Bad For You Or Good For You?
July 27, 2017 12:14 PM
Systemic inflammation can be a mixed bag. On the one hand, inflammation can help you during a period of injury. On the other inflammation can indicate that you are high risk for a variety of illnesses including heart disease. A test for C-reactive protein can be valuable in determining inflammation in your system, but one must be cautious as it cannot tell you what is causing said inflammation. To deal with excessive systemic inflammation, a healthy program of diet and exercise can be very helpful
"Chronic, low-level inflammation seems to play a role in a host of diseases, including type 2 diabetes, heart disease, Alzheimer's, cancer and even depression. And even though the science on inflammation and disease is far from settled, tests and treatments are being promoted that claim to reduce that risk."
Read more: http://www.npr.org/sections/health-shots/2017/07/21/538377221/is-inflammation-bad-for-you-or-good-for-you
Vitamin B12 shots: Uses, benefits, and side effects
July 09, 2017 04:14 PM
Vitain B12 is an iportant vitamin that you should get each day. If you are not, your body suffers. There are supplements offered for those who do not get enough B12 through natural method. But, why is it so important that you have adequate amounts of B12 in the body? Are there any side effects of B12? What are the benefits? if you want answers to thee questions and more, you've come to the right place to find the answers.
"Vitamin B12 is an essential water-soluble vitamin that plays an important role in many functions in the body, including: DNA synthesis energy production nerve cell health red blood cell formation neurological function"
Read more: https://www.healthbreakingnews.net/2017/07/vitamin-b12-shots-uses-benefits-and-side-effects/
Seasonal Flu Reaches Epidemic Levels in US
February 06, 2017 05:59 AM
When you think about a horrible disease you may not think about the flu, but it's turning into an epidemic. This may have something to do with a lower number of flu shots being handed out. The CDC is looking into the way this may affect society, the flu could be very bad this year.
The Difference Between Type I and II diabetes.
There are mainly two different types of diabetes - Type 1 diabetes and Type 2 diabetes.
Type 1 diabetes is known as insulin-dependent or juvenile diabetes. It is a condition in which there is an absolute lack of insulin. Due to the attacking of the body's immune system, the beta cells which are present in the pancreas and are responsible for making and secreting insulin die. Thus, there are no cells available to make insulin. So, in this case, the body will die without getting supplemental insulin immediately or in near- immediate future. The only treatment for this diabetes is insulin shots. Almost 10% of the people get this diabetes.
Whereas in type 2 diabetes, beta cells are present therefore insulin is also present. This diabetes is also known as non-insulin dependent diabetes. Insulin production produced is less than the amount of insulin the body requires. Almost 90% get affected by this type of diabetes. Treatment includes proper diet, exercise, and pills.
Usually, type 1 diabetes starts during childhood whereas type 2 diabetes is usually diagnosed during adulthood. As type 1 diabetes affects mostly young babies and children, it is known as juvenile-onset diabetes. People who have type 1 diabetes lack total insulin whereas type 2 diabetics have too little insulin.
Even the causes of type 1 and type 2 diabetes are entirely different. It is not possible to prevent type 1 diabetes whereas type 2 can be avoided. But type 2 diabetes may be genetic also. It may be the result of obesity or high blood pressure. The symptoms of type 1 diabetes are very severe. Suddenly the child becomes feeble and sick; urination is increased, experience increased thirst, nausea, vomiting, stomach and abdominal pain, excessive fatigue, weight loss and decreased appetite. Immediate medical attention or usually hospitalization is required for the person suffering from these symptoms. On the other hand, type 2 is often diagnosed before the presence of any symptoms.
What causes cancer? The five vectors of chemical assault on your health
December 03, 2016 06:59 AM
Cancer is a complex group of diseases with many possible causes. In this section you can learn more about the known causes of cancer, including genetic factors; lifestyle factors such as tobacco use, diet, and physical activity; certain types of infections; and environmental exposures to different types of chemicals and radiation.
"Now imagine that the fuel that's feeding those malfunctioning clone-soldier-making machines comes from several sources."
Your Mood and mental health
Bipolar disorder is a terrible mental disease that affects millions of people worldwide. It is characterized by periods of severe depression, followed by periods of extreme euphoria. It can be rapid cycling, which means the person with the disease goes through many moods a day.
Once you figure out what the underlying cause such as brain chemistry, then you can take a natural approach to help boost serotonin or dopamine.
Always remember to be careful if on MAO inhibitors or SSRI inhibitors before taking natural remedies like 5-htp or dopabean to mess with serotonin and dopamine levels in the brain.
Echinacea Health Benefits
June 12, 2014 08:32 PM
What is an echinacea?
Echinacea is a herb that is local to North America, and develops common in the mid-west. It is named a famous restorative herb, with other normal names, for example, purple cone blossom, and American cone bloom. Battle microorganisms, infections and different contaminations, knew Echinacea. This herb utilized to empower the insusceptible framework to battle diseases, secure from the normal cool, and decrease the length of time of a frosty. Echinacea is additionally known to be compelling at treating moderate recuperating wounds and skin contaminations, by empowering new tissue development. This herb might be found in wellbeing nourishment stores or on the web.
Benefits of echinacea
The profits of Echinacea are surprising. It has turned into the most well known natural solution for colds and influenza. Its anti-toxin and resistant boosting properties make this herb a standout amongst the strongest recuperating herbs accessible. The properties of this plant respond with the cells in the body and quicken the mending methodology. The resistant boosting properties make Echinacea, especially supportive in battling upper respiratory diseases, for example, nasal clogging, sore throat, and many people more contaminations. It additionally profits the circulatory system by separating the blood and disposing of poisons, its known as one of the best blood purifiers in nature.
The bloom and base of the plant are in charge of the recuperating parts, and fortifies new tissue development for wound mending. Its calming impacts and topical operators serve to battle incendiary skin conditions. Numerous individuals have approached to say that they were cured of different skin issue, with topical requisitions of Echinacea treatment. It likewise has a cortisone sort element that assists with the mending of wounds, and control the incendiary responses to hypersensitivities. At the point when utilized topically Echinacea is against incendiary, disinfectant, and analgesic, to battle an assortment of creepy crawly nibbles, Eczema, and many people more skin aggravations. It can likewise be utilized as a mouthwash.
At the point, when utilized alongside other homegrown cures, for example, garlic or vitamin c, it can decrease the length of time of a sickness. It is accepted to work through transient incitement of the insusceptible framework. Studies have demonstrated that taking this herb regularly can decrease your shots of contracting a bug or influenza throughout the year. In the event that you have caught an icy you can harvest the profits of Echinacea even half path through the icy, yet it works best on the off chance that you take it when you first begin to contract any of the manifestations connected with a cool.
Much of the time, Echinacea does not result in any symptoms for clients. For a protected and common approach to guarantee your well being and fitting capacity of your invulnerable framework you cannot discover a more trusted item. The calming impacts and topical operators help to battle skin conditions. In case you're searching for a regular incitement of the insusceptible framework, a mitigating topical executor to help against skin issue, this herb will do the greater part of this and the sky is the limit from there. It has a fabulous security record, and is generally endured by most individuals, with no known danger.
Why Would You Want A Time Released Chromium Supplement?
January 03, 2013 04:34 PM
Chromium is an important trace mineral for carbohydrates and fats processing by the human body. With the recent eating habits of refined foods, it's generally naturally deficient to many people. It's recommended to consume at least 50 micrograms of it each day. Similarly, the eating habits of today expose majority of people to diabetes. Chromium plays a major role in helping the body cells respond to insulin.
In addition, a sufficient level of the mineral availability to the body leads to lower insulin necessity. On the other hand, its deficiency in the body has been associated with diabetes. It helps prevent diabetes by aiding insulin in glucose metabolism as well as preventing insulin resistance for victims already using insulin shots. It's generally low in the blood but it plays a major role of enhancing insulin efficiency thereby helps control blood sugar levels.
You can get chromium from foods like broccoli, green beans, grape juice, potatoes, bananas, beef, orange juice and apples. There are also supplements that come in various forms and strengths. For instance, there are chromium picolinate, chromium chloride, chromium polynicotinate, chromium GTF and many others. These supplements differ in their absorption rates but have been proven in several studies to lower blood sugar as well as cholesterol. Some supplements are also safe to take alongside other medications. However, such a decision should always be taken with the consent of a medical doctor.
Victims of type 2 diabetes have usually been found to have low levels of chromium in their bodies. Due to this reason, supplements have greatly assisted such individuals tackle diabetes. Similarly, women suffering from gestational diabetes have had their blood sugar levels drop after using chromium picolinate. The dosage to use varies but many doctors prescribe 1000 mcg every day for victims already suffering from diabetes. Vitamin C has been found to hinder the uptake of chromium. It's, therefore, essential to watch out what you are consuming if you will be taking the supplements.
Sustained release chromium will help keep blood levels high with this important mineral and help one manage their blood sugar better.
Information on slippery elm bark
February 09, 2012 11:56 AM
The Ulmus fulva tree is medicinal tree that was commonly found in deep soil areas that are rich in nutrients. The type of tree was predominantly found along stream banks and areas with low hillsides but rocky. The medicinal properties of the slippery elm bark were first discovered by Americans of Indian origin where they used it in healing of wounds and preservation of meat. They placed it in water and it swelled and produced a sticky substance that was soothing.
Later on, English early settlers were able to discover the wide use of the tree and to improve their medicinal remedies, they added it during their manufacture especially those that were mainly used to treat wounds, cold sores and boils. They also used it to relieve urinary tract diseases, sores of the throats and coughs.
During wars, the tree was largely used as an antiseptic in form of a cream for treating wounds caused by gunshots and as the only food that was available for people to eat. This food was made by mixing the tree with water to make gruel which was very nutritious and everyone including the little children, the old and the sick were served to eat. People were also ingesting it in order to treat coughs, sore of the throats as well as respiratory infections.
The tree has numerous health benefits and the main one is the soothing property it has hence it has been widely used to treat inflammation of the throat plus esophagus. Traditional medicine men have added it in their cough treatments to sooth sores of the throats and irritations in the mouth.
It has also been used to prevent constipation, constant diarrhea and a neutralizer for excess acids in the linings of the intestines. Its gum like nature makes it a perfect meal for people suffering from cancer or ulcers and is the only food that remains in the stomach to sustain them and provide energy during hunger.
Because of its high nutritional content, it is widely used as food and when grounded to powder it can be used to make porridge, which is very nutritious and is similar to the porridge made from oatmeal. It helps babies who have digestion problems and is ideal for sick people and the aged.
It has been widely used to lubricate and relieve pain during childbirth and is very good in removing toxins and other impurities from the body. It is a natural preservative, an antiseptic for healing wounds and may be applied as a dysentery injection. If used earlier, it can be useful as a dental treatment to kill bacteria in the tooth.
It is used widely recommended as a perfect natural alternative treatment for heart problems as compared to other medicines, a suggested treatment for cancer and in females, it has been useful in treating various infections and diseases affecting their organs. Indeed the slippery elm bark is a significant part of the tree and a natural remedy for a wide number of diseases.
November 12, 2008 09:51 AM
Gymnema sylvestre is found naturally in central and southern India, where it has been used in traditional Indian medicine for almost two thousand years. It is known as 'gurmar' in ancient Indian texts, a word meaning 'sugar destroyer', which gives an indication of its uses in medicine.
It is used to reduce the absorption of glucose into the body, and also reduce the sweetness of foods, both of which are desirable for those wishing to lose weight and to reduce the level of sugar in their blood. It was used for this purpose in Ayurvedic medicine, subjects being given the leaves to chew. As with many other ancient Ayurvedic remedies, this use of gymnema sylvestre has passed into modern times, and has sound scientific basis. First, however a bit more about the plant itself.
It is found predominantly in the Western Ghats, and also to the west of the mountains, around coastal Goa. It is a vinous plant that climbs on other bushes and trees, known in Sanskrit as Meshasringa, or ram's horn after the shape of the leaves from which the supplement is extracted. For what it's worth, the official name seems a mix of Greek and Latin (gymnos(Gr) - naked and Silva (L)- forest) for naked forest. That, however, is irrelevant to its uses, so let's have a look at the science involved and the active ingredients in the plant.
The main constituents are terpenoid saponins known as gymnemic acids, so one can assume that they were first found in this plant. They are glycosides, including hodulcine and ziziphin, which act as sweetness inhibitors so that there is no sweet taste in anything that is sweetened by sucrose. There are over 20 types of gymnemic acid in the leaves, of which the strongest, Gymnemic Acid 1, can suppress the sweetness even of artificial sweeteners such as aspartame.
These are not irreversible effects, and last only about 10 minutes, after which normal sweetness is detectable by your tongue. During the active period, however, a solution of normal sugar will taste like ordinary unsweetened water. However, is this just a matter of taste, or does it affect the sugar itself?
Studies have shown that animals fed the leaves of Gymnema sylvestre develop hypoglycemia, probably because it stimulates the pancreas to generate insulin that reduces the level of sugar in the blood. Further studies have shown the presence in the leaves of a number of types of acylated derivatives of deacylgymnemic acid. There are well over a dozen types of saponins known to be contained within the leaves.
Other chemicals found include anthraquinones, flavanoids, chlorophylls, querticol, phytin, a number of glycosides and anthraquinones. The bush also contains alkaloids, although these are constituents in most plants used in ancient remedies. This is by no means all of the chemicals discovered, and many of the minor benefits of using it could be due to the minor constituents of this amazing little leaf.
A study of the above constituents will reveal a few antioxidants, and it is no surprise that the extract from Gymnema sylvestre also possesses anti-inflammatory properties. Gymnemic acid is believed to have a similar chemical structure to saccharose, and the plant extracts can be used not only to reduce a craving for sugar, but also to treat digestive problems and high cholesterol levels. So what scientific evidence is there other than the obvious effects reported by those that use it?
A study in the UK in 2005 found that an aqueous extract of Gymnema sylvestre caused the secretion of calcium and insulin from mouse and human cells to be increased at a specific concentration without affecting the cellular function. This means that the supplement can be used to stimulate the secretion of insulin with people with Type 2 diabetes without otherwise affecting health. Its usefulness to diabetics is obvious, but there are other health benefits to those that are not diabetic.
Anything that modulates a sweet tooth must be of use to those seeking to lose weight, particularly if they feel the need for sweet foods. In fact Gymnema tends to reduce food cravings for carbohydrates and sweets, and can be used by those seeking a natural means of curbing their appetite for sweet and sugary foods. Because excess weight can lead to diabetes,
Although there have been many discussions about the biochemical mechanism of the gymnemic acids in this effect on taste, recent evidence suggests that the phytochemicals act on both your taste buds and on those parts of the intestine responsible for absorbing nutrients from digested foods.
Not only that, but studies have also indicated that Gymnema sylvestre removes the bitterness of acerbic chemicals such as quinine in the same way that it removes the sweetness form cakes and candies, and if you drank tonic water it would taste just like water. On the other hand, if you ate an orange, you would taste the acidity but not the sweetness.
The way to use this remarkable supplement is to follow the instructions, and within about a week you will be able to control your appetite much better, and any cravings for carbohydrates you previously had will be much reduced. After a month or so, you will notice an accelerated rate of weight loss if you had been overweight, and diabetics will find a significant reduction on blood sugar between insulin shots.
Gymnema sylvestre can take care of any sugar or carbohydrate cravings, and is of significant use to the overweight, obese or to diabetics, and the mechanism by which it works has now been all but understood, although there are still some biochemical secrets that this amazing plant has yet to reveal. This amazing herb can be found at your local or internet vitamin store.
Eighty Seven Percent of All Type 2 Diabetes Can Be Prevented Naturally
January 24, 2008 05:06 PM
It is a fact that almost 90% of Type 2 diabetes can be prevented by attention to diet and the use of specific supplements. However, before having a look at these possibilities, we shall first have a look at what type 2 diabetes is so that the means of prevention can be better understood.
Diabetes is a condition, not a disease. It cannot be passed from one person to another, and there is evidence that it is hereditary since it tends to run in families. In the past it tended to develop later in life, although the modern lifestyle appears to have made it more common now in children and young adults.
Diabetes occurs when the level of glucose in your blood becomes higher than it should be. The reason for this is twofold: either the body produces no or insufficient insulin or it cannot use the insulin that is produced. Sugars and other carbohydrates are metabolized to glucose that is the body’s source of energy. The parts of your body that do this are the mitochondria that are contained within your body cells, and the hormone insulin is essential in allowing this to happen.
When the concentration of glucose in your blood reaches a certain level, the pancreas secretes insulin into your blood. The insulin is synthesized in special cells called the islets of Langerhans, after the person who discovered them. Also produced is glucagon which is also secreted into your bloodstream, and the glucagons and the insulin work together to ensure that your blood glucose levels remain stable (when everything is working correctly).
Glucagon is secreted when your glucose levels are low, and its presence in the bloodstream stimulates the conversion of the emergency energy store in the liver (glycogen) to glucose in order to maintain this stability. Insulin, on the other hand, is released after you have consumed a meal, and your glucose levels are high. What insulin does is to stimulate the cells of your body to convert glucose to energy and either use it immediately, or store it as glycogen for use later. By means of these two substances, the level of glucose in your blood is maintained at safe levels – normally.
If something happens to the supply of insulin, then the blood sugar level will continue to rise until the bloodstreams contains too much glucose, a condition known as hyperglycemia. The symptoms are excessive thirst, a frequent desire to urinate, fungal infections or thrush around the genital area (due to yeasts and sugar fermentation), and various others such as mood swings, cramps, dizziness and a feeling of tiredness and weakness.
Type 1 diabetes occurs when the body produces no insulin, and the only possible treatment is continual insulin injections. Type 2 diabetes is defined in two ways. Either your body does not make enough insulin for your needs, or the cells in your body cannot use the insulin produced properly. It is Type 2 diabetes we are concerned with here, and that we shall be exclusively discussing. With Type 2 diabetes, insulin shots can be provided, but there are other factors that can also help to resolve the problem.
Before discussion treatment or prevention, you should be aware of the complications that Type 2 diabetes can lead to. Hyperglycemia is not common with this type of diabetes, but it can develop. If it does then it can be a life-threatening condition needing a rapid injection of insulin into the bloodstream Symptoms prior to the critical stage are drowsiness and dehydration, although as stated, this is more commonly associated with Type 1 diabetes where regular insulin injections is the normal treatment.
Longer term complications of Type 2 include kidney damage, hardening of the arteries, eye problems, impotence and problems with your circulation. Nerve damage can also occur, and it is important that you avoid these by changing your diet and lifestyle. These problems occur if you have had high blood glucose levels over a long period of time, and you therefore have time to take the steps necessary to avoid them if you start now. The same steps will also help you to avoid the condition from occurring. So what are these steps you should take?
The first is to look carefully at your diet. A healthy balanced diet is essential if you are to beat your condition naturally and avoid the potential longer term side effects. Diabetes is associated with the overweight and obese. That is not to say that only these people become diabetic, but the majority are. Most people with Type 2 diabetes are overweight, and although around 65% of Americans are overweight or obese, a considerably higher proportion of those with Type 2 diabetes are overweight.
The first and obvious action to take to avoid this type of diabetes would therefore be to lose weight, and adopt a healthy diet that is free from junk food, trans fats and alcohol, all of which contribute to obesity. The next is to look to your blood pressure and keep it normal, and also to keep your low density lipoproteins (LDL) low. These affect the propensity for your blood cholesterol to deposit in your arteries, especially if they are oxidized by free radicals. A good antioxidant content is therefore recommended in your diet. Although blood pressure and high LDL levels do not directly contribute to diabetes, they are risk factors that could increase the risk to your health if you are diabetic.
You should eat a diet that is high in whole grains and fiber, and eat lean meats and fish rather than fatty foods. Stick to complex carbohydrates that metabolize to glucose slowly and steadily, rather than starchy foods that produce a sudden sugar rush that will give you problems and could promote Type 2 diabetes in those that are prone to it.
Specific supplements that you could take include chromium picolinate that can not only be used to treat existing diabetes patients but also to reduce your chances of developing Type 2 diabetes. Studies involving the use of chromium picolinate on patients with this type of diabetes have been very positive, resulting in reduced blood sugar, lipid and insulin levels. The optimum dosage is around 500 micrograms twice daily. Such treatment has been shown to both prevent and reverse Type 2 diabetes.
Magnesium is another specific supplement that studies have suggested can lower the risk of developing this type of diabetes. Magnesium rich foods have also been found to be effective, and the fact that a magnesium deficiency can lead to diabetes supports the findings that its use can help to prevent it. Green leafy vegetables such as spinach, and beans nuts and seeds are generally rich in magnesium.
Vitamin D can also help protect against the development of diabetes. Although the research is relatively new, it has been established that the cells that produce insulin are affected by a lack of vitamin D in the blood, and low levels of vitamin D can also led to insulin resistance. If you spend more time out in the sun, you should have less chance of contracting Type 2 diabetes, although you could also take a supplement.
Although Type 2 diabetes is not as serious as Type 1, no form of diabetes is desirable to have, and ultimately both types can be extremely serious. You should do what you can to avoid diabetes, and Type 2 is easier to avoid then Type 1. Diet, weight and supplementation as described above will all help to avoid contracting this condition, so follow the advice, especially if you are overweight and have a sweet tooth.
Take Charge Of Your Health With Herbal Bio-Identical hormones
November 04, 2007 03:17 PM
Bioidentical hormones assist women in overcoming acute menopausal symptoms, while improving skin. They help by strengthening bones, keeping the mind sharp, promoting energy and well-being, and helping to preserve vaginal tone and resist vaginal dryness. In men, these hormones add energy and vitality, while improving muscle tones and mental sharpness. Bioidentical hormones (BHRT) are exact duplicates of the hormones that are produced by the body. However, they are much more easily metabolized by the body into safe forms of estrogen than their counterparts, which stimulate toxic metabolites. When they are used in physiologic amounts, bioidenticals carry much fewer risks than synthetic hormones. However, despite the fact that research supports their use and proves them safe alternatives to prescription drugs, few physicians are actually using these hormones in their practices.
Those patients, who wish to address menopausal and andropause symptoms, or to achieve lifelong hormonal balance in order to prevent illness, often do not know where to go to find a comprehensive bioidentical hormone replacement program. Instead, they read whatever they can to formulate a plan and purchase various products that are available over the counter, often spending precious time and money on programs and products that don’t do what they’re expected to do. One of the most common errors among people is putting together a program based solely on symptoms instead of first checking hormone levels. Symptoms may overlap from one hormone pattern to another. If you try to replace or augment specific hormones without having an accurate test of the levels first, your results will seldom be good.
If your doctor is prescribing transdermal hormones, make sure to do a saliva self-test to measure your hormones levels as it is much more accurate and revealing than other types of tests. You can submit your samples to Mead Labs, where you will actually receive a telephone consultation from a health professional to interpret your results followed by a program of products prescribed especially for you from one of their medical professionals. With your own results, you can learn a lot about the exact state of your hormones instead of blindly guessing from symptoms which may be similar. For example, men may not need testosterone shots or transdermal patches, as the results may show estrogen dominance. The answer for this is not adding more testosterone, because the man could be converting testosterone into estrogen, but instead a program including special herbs and nutrients may be much more beneficial. No matter your gender, your health professional at Mead Labs will design a safe and effective program based solely on bioidentical hormones, herbs, and nutrients first. In the past years, when prescription, non-bioidentical HRT was used by any women with menopausal symptoms, there was no testing to find out what kind of imbalance was actually occurring. Proponents of BHRT are trying to ensure that this method of prescribing the same combination and amounts of medications to everyone is not used with natural hormones. Because hormone profiles and levels can vary significantly from person to person, even those people in the same gender, testing hormones levels and obtaining recommendations from a medical professional who is experienced in BHRT are the key points to ensure you benefit from this therapy.
7-Keto - The Key to Healthy Aging
June 21, 2005 05:05 PM
The global population is aging at an alarming rate and causing an explosion in health care costs, insurance premiums, cosmetic surgery and more. In the U.S. alone, more than one million baby boomers are expected to live to 100 years of age or older. This increased life expectancy presents a whole new set of health concerns that the medical community has not had time to address, since there is a greater need to care for age-related health problems in this ever-growing elderly population.1
Aging and the Decline in Vital Nutrients
We all grow old at the same rate but people age at different rates. Aging is a process of gradual changes that occur to varying degrees in each of us. Interestingly, the aging process is composed of different components and interactions, some of which can be impacted. One such component is the declining level of essential biological compounds, which causes our bodily functions to slow and become dysfunctional. Our organs don?t work efficiently, our immune system becomes lazy, we lack energy, our metabolism drops and we gain weight easily.1 7-oxo DHEA (7-Keto™) is a naturally occurring compound that declines with age.2 Replacing this key metabolite helps promote a healthy immune system and maintains resting metabolic rate at levels that accelerate weight loss during standard weight reduction programs.
Aging and a Healthy Immune System
Numerous changes occur in the immune system with advancing age, probably contributing to decreased immune responsiveness. Although all segments of the immune system are affected, investigators have most consistently identified declines in cellular or T-cell mediated immune function in the elderly. The decline in T-cell immune function is generally associated with an increased susceptibility to foreign organisms. For example, individuals with age-related declines in cellular immunity have an impaired response to vaccinations, making them more susceptible to health imbalances even though they have had their shots. In a clinical study presented at the Federation of American Societies for Experimental Biology meeting in April 2004, the effect of 7-Keto on elderly immune function was evaluated. Healthy elderly adults were given 7-Keto orally twice daily over a period of one month. The study revealed that 7-Keto augmented several key T-cell mediated immune function parameters compared to placebo administration.4
Age-Related Weight Gain
Age-related weight gain and obesity are approaching epidemic proportions in our country.5 Weight gain is a disorder of energy balance involving energy intake and/or expenditure. Low energy expenditure, a drop in resting metabolic rate (RMR), is a challenge during most weight loss attempts due to age, calorie restriction, lack of physical activity or a combination of factors. RMR represents 60% of total daily energy expenditure. Maintaining a higher RMR as we age and during weight reduction programs helps us achieve and maintain a normal weight. Furthermore, compounds with the thermogenic potential to achieve even minimal increases in daily energy expenditure of 2-3% may have clinical relevance in preventing the decline in RMR with calorie restricted diets or weight loss, and in decreasing the risk of regaining weight. 7-Keto, a non-stimulant thermogenic compound, has been shown to significantly increase energy expenditure in humans.6 A recently completed clinical study, also presented at the Federation of American Societies for Experimental Biology 2004 meeting, revealed that administration of 7-Keto to overweight adults in conjunction with a calorie restricted diet effectively reversed the decline in RMR normally associated with dieting. Obese participants following a calorie-restricted diet demonstrated a 5.4% increase in daily RMR with 7-Keto.7 The magnitude of the increase in RMR by 7-Keto is clinically relevant, and represents a promising agent for enhancing thermogenesis and weight loss in obese individuals on calorie-restricted diets. Additionally, 7-Keto has been shown in two confirmatory published clinical studies to result in three times more weight loss compared to diet and exercise alone. It has a favorable side effect profile and is easy and convenient to take.8,9 Our life expectancies will likely be longer than those of our parents, and our quality of life during those years will depend on how well we take care of our bodies now. Undoubtedly, the science of aging will give rise to new and exciting technologies to help us age more gracefully and healthfully. Maintenance of healthy immune function is keenly needed for improved quality of life in the elderly. Dietary manipulation and supplementation has been identified as a method of immune system renewal, and supplements such as 7-Keto may play an important future role as immune system modulators. Moreover, the addition of 7-Keto to any weight loss program will offer vital support of energy expenditure and help with the attainment of a manageable and healthy weight into our older years.
1. 1995 White House Conference on Aging, ?Executive Summary: The Road to an Aging Policy for the 21st Century," February 1996: 17-18. 2. Marenich LP. Secretion of Testosterone, Epitestosterone, Androstenedione, and 7-Keto-Dehydroepiandrosterone in Healthy Men of Different Ages. Prob Endokrinol. 1979; 25(4): 28-31. 3. Ginaldi L, De Martinis M, D?Ostilio A, Marini L, Loreto MF, Quaglino D. Immunological Changes in the Elderly. Aging 1999; 11(5): 281-286. 4. Zenk JL, Kuskowski MA. The Use of 3-acetyl-7-oxo-dehydroepiandrosterone for Augmenting Immune Response in the Elderly, Abstract Presented at the meeting of the FASEB, April 17, 2004, Manuscript submitted for publication. 5. Flegal KM, Carroll MD, Ogden CL, Johnson CL. Prevalence and Trends in Obesity Among US Adults. 1999-2000. JAMA 2002;288:1723-1727. 6. Astrup A. Thermogenic Drugs as a Strategy for Treatment of Obesity. Endocrine 2000;13(2):207-212. 7. Zenk JL, Leikam SA, Kassen LJ, Kuskowski MA. A Prospective, Randomized, Double Blind Study to Evaluate the Effect of HUM5007 and 7-oxo DHEA on Resting Metabolic Rate in Overweight Adult Men and Women on a Calorie Restricted Diet, Abstract Presented at the meeting of the FASEB, April 17, 2004, Manuscript submitted for publication. 8. Kalman DS, Colker CM, Swain MA, Torina GC, Shi Q. A Randomized, Double-Blind, Placebo Controlled Study of 3-Acetyl-7-Oxo-Dehydroepiandrosterone in Healthy Overweight Adults. Current Therapeutic Research 2000;61: 435-442. 9. Zenk JL, Helmer TR, Kassen LJ, Kuslowski MA. The Effect of 7-Keto Naturalean on Weight Loss: A Randomized, Double-Blind, Placebo-Controlled Trial. Current Therapeutic Research 2002; 63:263-272.
John L. Zenk, M.D., is Chief Medical and Scientific Officer for Humanetics Corporation and President and Medical Director of Minnesota Applied Research Center, both located in Eden Prairie, MN. He has spoken nationally and internationally on the subjects of integrating conventional and complementary medicine, anti-aging technologies, evaluating the effectiveness of alternative medicine, and dietary supplement research and development. He is author of the book Living Longer in the Boomer Age, and co-author of the book Age Wise and is a frequent contributor to national media. He has served as Principal Investigator for 15 controlled clinical studies, three of which were recently published in national peer-reviewed journals, and has presented abstracts at the 11th World Congress for Food Science and Technology and the Federation of American Societies for Experimental Biology.