Search Term: " Aspartate "
Can Glutamine Improve The Immune System, Lymphocites and Inetstinal cell Enterocytes?
May 07, 2014 11:29 AM
Glutamine is considered to be the most abundant natural amino acids which is a building block of proteins in the body. Although the body can already make enough glutamine on its own, extreme stress is the type you could experience after heavy exercise or from injuries can't naturally aid help those pains on its own. The body may need a bit more glutamine in order to truly eliminate those kinds of ailments. Most glutamine is naturally stored in the muscles and lungs.
Zinc monomethionine and aspartate
January 25, 2014 09:24 AM
What is ZMA?
Zinc monomethionine and Aspartate commonly known as ZMA and Magnesium Aspartate is a supplement mostly used by people involved in great excises such as the athletes, gymnasts, and bodybuilders. Supplements help in maximum building of body muscles though some could think about creatine, weight gainers, testosterone boosters and protein powder. ZMA is one of the great supplements.
Importance of ZMA
ZMA is of great importance when it comes to immune boosting. Some of the body occurrence could damper somebody’s ability to train well. Zinc supplementation gives appositive effect as it decreases the levels of oxidative stress and it reduces inflammation in the body. Also, the ZMA addition of this supplement to the daily diet since it happens to be one of the nutrients. These nutrients are frequently found in daily consumed foods like crab, oysters, pork shoulder and beef shanks. ZMA boosts the testosterone levels in the body since it is muscle building supplement that has been shown to boost testosterone levels. This substance contains zinc, magnesium together with vitamin B6.
The research has revealed that the usage of ZMA supplement increases the testosterone levels for about 30% and the strength could be increased by 250%. The ZMA testosterone boost makes a great progress in weight training. It also develops strength. The presence of this supplement is of great benefit to sleep as it boosts the testosterone hormone that helps in getting enough sleep. The sleep helps muscles by repairing them and giving enough rest.
The Magnesium presence could help in building of the lean muscles in from their ass. This gives the muscles enough oxygen as the function and recovering from their workouts and build new muscles. Still edge can be gotten by taking ZMA though zinc and magnesium contain high quantity of multivitamins, a condition called competing nutrients. This condition is by when one nutrient cancels the effect on another nutrient.
For the case of weight training, the presence of calcium in your body can cancel out or limit the effects of zinc and magnesium that you ingest through food or a multivitamin.
How Does Lithium Help with Memory and Mental Disorders?
July 04, 2011 08:42 AM
Lithium And The Brain
Lithium is a chemical element whose ions have been observed to display pharmacological effects. It is best known as a treatment for mania and remains to this day an approved drug for mood disorders in several countries, including the US. It has been associated with countless scientific studies since the latter half of the 19th century. It is one of the most extensively studied of all drugs that alter mood.
Depression is an ancient disease of the mind that was referred to as melancholia in the ancient world. It has been noted in religious writings over the centuries. High energy levels and mental hyperactivity characteristic of bipolar disorder were once associated with supernatural causes. Religious beliefs have historically considered mental disorders as the work of the devil, and melancholia is not an exception.
Melancholia and mania were two separate mental conditions. The former was always tied to evil forces whereas the latter were thought to be triggered by other supernatural causes. Early Greek and Roman physicians noted that active behavior deemed to be pathological could be cured by drinking spring waters. Research have studied and reported that these spring waters actually contained lithium salts.
Manic depression was first posited in the 1950s to be a mental illness distinct from both melancholia and mania. It was in France when two psychiatrists independently observed the type of insanity that oscillates from between bouts of depression and mania. It was later categorized as a specific type of psychosis in that the condition was acute, and thus the patient functions normally after recovery.
Lithium was introduced as a treatment for manic depressive disorder in the form of lithium carbonate in the first half of the 20th century. Its use was discovered when lithium urate produced tranquilizing effects on animal subjects. Lithium salts were used as tranquilizers shortly after. Human experiments have proven to be effective in controlling patients chronically suffering from bouts of manic disorders.
Bipolar disorder is now the widely used term in psychiatry, though manic depression is still preferred by many medical professionals. It was first used in the 1950s to describe oscillations between two polar behaviors: mania and depression. It is a subtype of depression, the other one being major depression or unipolar depression. Lithium remains a drug for mania amid its changing descriptions.
Medicinal concentrations of lithium are generally considered safe in that they produce no apparent psychoactive effects. Instead, they work as a therapeutic treatment. It has been widely established that lithium possesses properties that stabilize mood, though its mechanism of action is still a matter of controversy. It is believed that lithium rebalances brain chemicals and alters gene expression.
Lithium appears to have an impact on several neurotransmitters present in the central nervous system, such as glutamate and serotonin Inasmuch as these neurotransmitters are noted for their role in mood and memory, some sources have ascribed nootropic effects to regular intake of lithium supplements.
Lithium is a wonderful supplement available over the counter. Try some Lithium today and feel the difference!
How Does Taurine Help the Brain?
May 13, 2011 01:09 PM
Taurine is an amino acid often added to energy drinks. There have been several theories on how taurine affects brain chemicals and improve cognitive function. For many years, it has been compared to caffeine due to its effects on the human brain that appear to enhance mood. Its exact mechanisms of action remain a mystery to the scientific community, but recent studies are believed to be closing in.
It has long been known that taurine crosses the blood brain barrier, allowing it to exert some effects on several neurotransmitters found in the central nervous system. It has been tied to the alleviation of many mental illnesses, such as epilepsy, post traumatic stress disorder, clinical depression, bipolar disorder, and anxiety, making it the subject of a number of studies in the past few years.
Rebalances Brain Chemicals
It has been postulated that taurine influences the activities of neurotransmitters in the brain, but only recently has brain scientists been able to actually track its activities in the brain. A team of researchers at Cornell University managed to find a site for the neurological activity of taurine, with initial results pointing to its relationship with gamma the neurotransmitter aminobutyric acid, or GABA. The researchers do not discount the possibility that taurine may even have a receptor of its own.
Whether taurine interacts with brain chemicals is no longer debatable as it creates homeostasis in the central nervous system. It acts on receptors that the researchers discovered to be the same receptors present in GABAergic mechanisms. That being said, scientists remain inconclusive as to how its interaction with GABA receptors provides energy-boosting benefits as it is marketed in the food and drug industries.
Prevents Neuron Damage
The scientific community is convinced that taurine has neuroprotective properties. High levels of taurine in the brain have been observed to protect brain tissues from cerebral ischemia. Taurine has been linked to many metabolic pathways that are known to promote neurological health, such as the activation of glycine receptors and the regulation of enzymes called cysteine-dependent Aspartate-directed proteases.
In addition, taurine serves as antioxidants that protect nerve cells from cellular damage brought on by oxidative stress. The presence of taurine within cells reduces damage from calcium excesses and increases mitochondrial events. For decades, supplementation of taurine has benefited sufferers of brain ischemia, epileptic seizures, panic attacks, anxiety symptoms, and even alcohol withdrawal.
Enhances Cognitive Function
Taurine has already been associated with physiological functions the hypothalamus controls, such as sleep-wake cycle and responses to fatigue. In several laboratory studies, administrations of taurine by way of intraperitoneal injection have successfully induced social interaction in animal subjects. It is one of the amino acids that affect cognitive development, especially in children. While it is one of the most abundant amino acids in the brain, it is depleted as we age, making supplementation a good option.
Protect your brain with Taurine by taking it daily!
Huperzine And Memory
December 04, 2008 01:20 PM
Chinese club moss goes by the name Huperzia serrata, and gives its name to the sesquiterpene alkaloid it contains: huperzine A. This alkaloid has been found to be a superstar in the arena of brain-saving treatments for conditions such as Alzheimer's and age-related senility. Studies in China have found up to 60% improvements in the cognitive functions of such patients, and its potential has been recorded in the Journal of the American Medical Association. This is no mere folk remedy, and is the subject of serious study.
Known as Qian Ceng Ta, Chinese club moss has been a part of traditional Chinese medicine for centuries for the treatment of fever and inflammation, which is not surprising considering that most plants contain antioxidants and anti-inflammatories. However, what is unusual is the fact that it has also been found effective in treating some forms of dementia and depression, and also helps to reduce the incidence of panic attacks in those susceptible to them.
Not only that, but the plant has been found to possess diuretic properties, and a reduction in the swelling associated with water retention could also help to reduce the pain and other effects of swelling and inflammation. However, for now it is its effect on the brain that we are concerned, and research has indicated the likely mechanism by which huperzine A works.
Huperzine is an enzyme inhibitor - specifically inhibiting the enzyme acetylcholinesterase that breaks down acetylcholine, a neurotransmitter involved in the processes of memory, learning and mood. Outside the brain, it is involved in the movement of skeletal muscle tissue as well as in the regulation of cardiac and other smooth muscles such as those of the blood vessels.
When acetylcholinesterase (AChE) attacks acetylcholine (ACh), the latter attaches to a chemical site on the enzyme where it is then destroyed. It is a deliberate function of the body, designed to terminate a synaptic transmission. The purpose of a neurotransmitter is to allow the transmission of an electrical impulse form one nerve cell to another over a gap between them known as a synapse. Once the transmission has been completed, the enzyme can destroy the neurotransmitter, and then another takes its place. In fact one molecule of AChE can destroy around 5,000 molecules of ACh.
However, with age and for other reasons, these neurotransmitters can become depleted so that it becomes increasingly more difficult for brain cells to communicate with each other, and their destruction becomes undesirable. There are drugs available to help prevent this happening (e.g. donepezil, galantamine and tacrine), and so help to improve the memory and mental function of people as they grow older or contract conditions such as Alzheimer's disease.
Huperzine A has been found to take up the site in the acetylcholinesterase molecule that would normally have been used by the acetylcholine, and so save it from destruction. The more Huperzine A molecules present, the more acetylcholine available to pass messages between brain cells, and the stronger the cognitive function of the subject or patient. The pharmaceutical drugs mentioned in the previous paragraph work in exactly the same way.
This is a very specific reaction, one molecule adopting exactly the same space as the other, and has been proved scientifically by comparing the physical shapes of the two molecules. It's just like a jigsaw puzzle, where only one piece can fit into each position. Except here there are two: Huperzine A and acetylcholine both fit into the exact same place in the chemical structure of the acetylcholinesterase molecule.
The biochemistry of the reactions involved is very complex, and shall not be discussed here, but the upshot is that Huperzine A can do exactly the same job as modern drugs to avoid this hydroxylation of the ACh needed for the proper functioning of your brain.
In fact, clinical trials have indicated Huperzine A not only to be comparable in effect to the drugs current used, but also likely safer with respect to the possible side effects. This has still to be confirmed, but the National Institute on Aging is currently carrying out a trial to evaluate this claim in tandem with its effect on Alzheimer's disease. It has also been examined at Harvard University for its effect on epilepsy on patients with whom alternative pharmaceutical treatments have been unsuccessful.
Another suggested benefit of Huperzine A is that it is an NMDA (N-methyl D-Aspartate) receptor antagonist that provides protection against damage to the brain by an excess of glutamates, and that it can also help to protect nerve cells from damage. Since NDMA is responsible for the transmission of some types of pain, the antagonist can also act as an analgesic.
There are other benefits that Chinese club moss can provide, and myasthenia gravis is one of them. Although relatively rare, this is a serious condition in which acetylcholine receptors are deactivated on muscle cells. This is achieved through the autoimmune system malfunctioning and creating antibodies against the receptors, and the end result is paralysis and respiratory failure.
Huperzine A reduces the AChE available and so might possibly enable the acetylcholine to work more effectively and delay or even stop the deterioration of muscle function. When people hear of muscle paralysis they frequently forget that breathing requires muscle function, as indeed does your heartbeat. This is currently surmise, and studies are being carried out to determine whether or not this usage of Huperzine A is viable.
Another promising application of Chinese club moss extract is in preventing organophosphate poisoning. These pesticides permanently suppress acetylcholine. This results in seizures due to a lack of interruption of the signals from nerves to muscles. The seizures can result in rapid death from uncontrollable seizures, or from permanent contraction of the diaphragm muscle that allows breathing. Although no human studies have yet been carried out, animals given Huperzine A prior to organophosphate exposure have survived without seizures.
There are no doubts that Chinese club moss and the Huperzine A extracted from it are effective in preventing the suppression of acetylcholine, and in permitting the proper activity of this important neurotransmitter. It is finding an increasing number of potential uses beneficial to the human body, not the least of which would be a partial remedy for some of the effects of dementia and Alzheimer's disease.
Looking For A Calcium But Not Sure Which Is Best For You?
November 02, 2007 12:23 PM
Calcium is essential to good health, but if you are looking for calcium it can be confusing to decide in which form you take it. There are so many available and every one claims to be good for you, so why the difference? Why not just sell the best and let us all know what it is? Well, this same argument could be applied to all supplements that are sold in different forms, and also to many foodstuffs.
The supplement best for you might not be the best for the next person due to dietary requirements each persons diet is different, so it is better to learn about what is available then make your choice based upon knowledge rather than ignorance. It is not only the source of the calcium you have to bother about, but also the other vitamins that have be present to make sure that that the calcium is absorbed by the body in the way that you want it to be.
To understand that then you need to learn why the body needs calcium, other than just the bones and teeth that everybody knows about. After all, why else do we need calcium? It is only contained in bones and teeth – right? Wrong!
Although 99% of calcium is contained in your bones and teeth, 1% is contained in the blood, muscles and central nervous system. With out that 1% we would all die. Without teeth we would not. Calcium is essential for blood clotting and for the proper function of our muscles, brain and central nervous system. Calcium combines with phosphorus to create healthy bones and teeth, and is essential early in life to build up a strong skeleton. Note that phosphorus is also necessary so we also need an adequate supply of that mineral.
Calcium is essential to allow muscles to properly contract. Without that ability, muscles could not work, and a deficiency of calcium causes muscle cramps and spasms. The movement of the smooth muscles is regulated by a protein that is bound to calcium. This is just one of the uses of the calcium in the body that most people are unaware of.
Calcium also takes part in the binding process of the blood platelets during the coagulation of blood. Although most people are aware of the need for vitamin K and fibrin, in fact calcium is also essential in its interaction with the platelets in the coagulation cascade that eventually results in a blood clot that stops bleeding. Basically, without calcium, the blood could not form a clot. In addition to its effect on blood clotting, calcium also plays an essential part in the movement of ions through the membranes of nerve cells, and without it intercellular communication could not occur. Our nerve impulses would not occur and the body again would not be in a working condition.
However, the body has a way of modulating the calcium level in the blood past a minimum level needed for effective nerve cell communication, and below a certain level it can even use the calcium in the bones to divert to the more needy areas of the body. It is therefore not possible for the body to fail through a lack of calcium. The skeleton would disintegrate first. Nevertheless, nobody wants a disintegrating skeleton since that would be counterproductive to effective movement of the body, so a good source of calcium is essential for overall bodily health, not just that of the teeth and the bones.
There are many sources of calcium, but some are more suitable for absorption by the body than others. Chalk, or calcium carbonate, is an excellent source of calcium, but will fail to promote bone growth if your diet does not contain sufficient potassium, vitamin D, magnesium and strontium needed to make it work to build healthy bones. It is the most common on the shelves, and likely the cheapest, but not necessarily the best source. It is basically chalk or limestone, and only 10% of the supplement will actually become available for your body to use.
The bioavailability of a calcium supplement is a figure that indicates how much of the calcium is actually absorbed by the body during digestion. It is important that the supplement is digested and absorbed properly or the calcium will not be available for use. This availability is called the ‘bioavailability’. Calcium citrate has a bioavailabilty of 50%, but the size of the citrate part of the molecule is so large that only 10.5% of the molecule is available to the body as calcium. Not much more than the carbonate.
Calcium Aspartate is highly soluble and produced by reacting calcium with aspartic acid to form the soluble salt. It is much easier to assimilate and be absorbed by the body than any of the forms above. The amino acid, aspartic acid, delivers the calcium exactly to where it is needed, where it is absorbed and used. Although a bioavailability figure is not available, it is not the amount of calcium that is significant here but the fact that it comes with its own transportation system and is immediately available where needed.
If you want to calculate the availability for yourself, find the molecular weight of the particular calcium product, and then the weight of the calcium contained within it. For example, in calcium carbonate, CaCO3, the molecular weight is 100 (40 + 12 + 3x16) and the atomic weigh of calcium is 40, so the amount of calcium present in 1000g calcium carbonate is 40% or 400g. Only 25% of calcium carbonate is absorbed, so only 10%, or 100g, of calcium is available for each 1000g supplement.
Calcium citrate on the hand (Ca3(C6H5O7)2.4H2O) has a molecular weight of 570, so the amount of calcium present is 3*40*100/570 = 21%. Since the bioavailability of calcium citrate is 50%, the amount of calcium available is only 10.5%, or 105g in 1000g citrate. You can carry out the same calculation on all the molecules if you know how much is absorbed by the body.
The bioavailability is calcium Aspartate is 85%. Its molecular formula is [C4H6NO2]2Ca, and molecular weight 304. The calcium availability is therefore 40*100/304 = 13.16%. If 85% is absorbed, then 1000g provides 80% of 13.16 x 10 = 115.6g. The Aspartate therefore wins it.
Amino acid chelates can also be used as a source of calcium, and its bioavailability is improved tremendously by including vitamin D and magnesium in the supplement. The bioavailability of these calcium chelates are not quoted, but is claimed to be high. Whether or not it is as high as the aspartame is debatable, though it is claimed to be.
Calcium is a very important mineral for human health, and there are several different supplements that can be used. The bioavailability of the calcium is different in each supplement, though the organic forms, calcium Aspartate and amino acid calcium chelates appear to be the highest. When looking for a calcium supplement look for one with additional minerals added as mentioned above to help improve absorption and usability by the body.
Which Calcium is Best?
October 17, 2006 03:52 PM
Customers walking into a health food store today are faced with a vast array of calcium supplements. They might ask: which one should I pick? Which one is best? Not easy questions to answer. All calcium forms will accomplish the same task: providing your body with a nutrient that it needs to build healthy bones and teeth; however, which form of calcium has the features that you want in a calcium supplement? Looking at shelves of calcium products is kind of like shopping for a car; there are many makes and many models—some are basic and others are more sophisticated.
Fortunately, there are many forms of calcium to satisfy your needs. Like the car lot, a health food store offers many options; therefore, you have to select a calcium product that consumers will feel confident in taking regularly and that will provide the most benefit.
Some consumers have done research and will come armed with information. They have already made choices based on advertising, word-of-mouth or an article they have read. They already know the form of calcium they want, be it a “Ferrari” or a “Ford.” If the client doesn’t have a specific preference: asking these basic questions will help in the selection process:
1. Do you prefer tablets, capsules, softgels, liquid or powder?
2. Do you have high or low stomach acid?
3. Do you have absorption issues?
What is calcium?
Calcium (Ca) is one of the most important minerals found in our bones and teeth—99 percent of body calcium is found there. But the calcium molecule does not like to travel alone and, in its more basic state, it comes bounded to carbon (C), Oxygen (O), and/or hydrogen (H) molecules or in more complex form, it is bonded to organic or amino acids that act as stabilizing carriers. On most labels, the amount of calcium listed actually indicates the pure or elemental calcium because it is that amount of the calcium that is deemed important to our daily supplementation, not the complex of the materials with which it is bonded.
Where does calcium come from?
Other than the calcium found in bone, the only natural form of calcium found in nature is calcium carbonate, a calcium molecule bonded to one molecule of carbon and three molecules of oxygen (CaCO3). One of the most common minerals on the face of the earth, calcium carbonate is called calcite, aragonite or vaterite by geologists. In its geological form, it constitutes approximately four percent, by weight, or the earth’s crust.
Commercial sources of calcium carbonate used to make supplements are: limestone, dolomite, oyster cell, egg shell, coral and sea water (have you ever seen that white deposit left by hard water? That’s mostly calcium carbonate). Calcium carbonate is the starting material for all other forms of calcium supplements. From this starting material, calcium can be reduced to more concentrated forms, such as oxide or hydroxide or it can be chelated (bonded) to organic acids and amino acids to help support enhanced absorption.
Lets look more closely at the different forms of calcium that are available as supplements.
Calcium Oxide (CaO): this form is 71 percent elemental calcium and is also called “lime” commercially. This is one of the oldest and most inexpensive forms of calcium used in a variety of commercial applications and it is occasionally used in supplements where space and price are a factor. It sometimes can be found in inexpensive mass market calcium/mineral combinations or multivitamin/mineral products and in a unique algal calcium from Japan. Unfortunately, CaO is a strong alkali that may cause stomach distress, which is why it isn’t often used in health food supplements.
Calcium Hydroxide (CaHO): at 54 percent elemental calcium, it is the next highest source of elemental calcium and is also known commercially as “slaked lime.” It is used where space is an issue. Although it is also a strong alkali, it is more stable than calcium oxide. It is most often used as a component of multi-mineral formulations or in addition to other forms of calcium (i.e., calcium citrate) to provide potency where space is an issue. It is not often used as a single ingredient in health food supplementation. This is for people who want a high dosage of calcium from a minimum amount of pills in multi-mineral formulas.
Calcium Carbonate (CaCO3): at 40 percent elemental calcium, it is the most widely used form of calcium in single ingredient calcium supplements as well as combination supplements. Inexpensive and an abundant source of elemental calcium, it is the only form of calcium found in nature outside of bone. It is the primary form of calcium used in the mass market and in antacid products. This is for people who have high stomach acid and who need a buffering type of calcium. Also for people who want a high dose of calcium in a minimum amount of pills.
Calcium Citrate: at 21 percent elemental calcium, it is one of the most popular forms of calcium supplements in the health food market as well as the mass market. This calcium salt does not lower stomach acid as much as calcium carbonate. This calcium salt is usually recommended for people who have low stomach acid, have had stomach surgery or who need a form of calcium that will not lower their stomach acid further.
Calcium Gluconate and Lactate: these two forms of calcium are high soluble. Since the amount of elemental calcium is much lower (9 percent and 13 percent respectively), they are used more often in powder form and mixed with liquids or food. When mixed in a beverage, the calcium is already dissolved and is ready to be absorbed. This is the best calcium salt for people who have overactive bowels, who have trouble swallowing pills or who don’t like the taste of pre-formed liquid calcium supplements. These calcium powders can be mixed in juices or smoothies or added to food as they are virtually tasteless.
Calcium Orotate and Asporotate: In the mid 20th century, Dr. Hans Nieper, a German scientist, advanced a theory that orotic and aspartic salt forms of calcium are transported directly to cell membranes for better absorption. The Solaray brand developed an asporotate formula, which combines three organic acids: aspartic acid (-Asp), orotic acid (-oro) and citric acid (-tate) into one product. The asporotate formula has become one of the most popular calcium formulas and is exclusive to the Solaray brand. This product is for customers who appreciate the idea of combining the enhanced absorbability of three organic acids into one. Aspartate and citrate are also part of the krebs (energy) cycle and are natural to the body’s metabolic systems and, according to Neiper, calcium Orotate and Aspartate are mineral transporters that enter into the cells to facilitate enzymatic actions rather than being extra-cellular. For people who believe that intracellular calcium is of importance, calcium Orotate and asporotate may be good choice.
Calcium Hydroxyapatite: this is another “natural form of calcium usually as a mineral ash form bovine source bone. Bone meal is also a form of calcium from bovine bone. These forms of animal derived calcium are for customers who want a source that is closest to their own bone matrix. Not for vegetarians.
Calcium Amino Acid Chelates (*HVP): this form is calcium carbonate bonded (Chelated) to a form of amino acid complex such as whole rice concentrate or other grain source. This form is for customers who want the additional bioavailability of amino acids.
Calcium AEP: Another form of calcium endorsed by Dr. Hans Nieper who theorized that calcium would cross the cell membranes more readily when it was combined with phosphatidyl ethanolamine or Amino Ethanol Phosphate (AEP), a nutrient found in nerve sheaths. This highly specialized form is for very educated customers who are proponets of Hans Niepers theory.
So, which form is best?
Calcium, like cars, comes in a variety of forms. Isn’t it wonderful that we have so many choices? The point is, there is no best one, there are only individual choices. Although we have our favorites, taking a calcium supplement, regardless of which one it is, should:
Our primary concern when choosing a calcium supplement should be to provide our body with the right amount of calcium daily so that our skeleton and teeth can maintain proper mineralization and strength as the cells continuously break down and rebuild. The type of calcium complex we prefer is entirely up to us.
*HVP = Hydrolyzed Vegetable Protein
Triple Boron - Activate the Bone-Building Basics
September 19, 2006 06:15 PM
Lithium Aspartate improve brain function
January 03, 2006 05:32 PM
Lithium has long been known to be an effective therapy for Bipolar Disorder (manic depression) when taken in high doses. However, recent research has shown that low doses of lithium preserve and renew brain cells. Eight out of ten persons given lithium showed an increase in brain grey matter of 3 % after only 4 weeks. By promoting brain cell regeneration and increasing brain size lithium can function as an anti-aging nutrient for the brain.
Lithium Aspartate may help increase brain function when taken daily. have you had your lithium today? :)
PREGNENOLONE - The Balancing Hormone
June 04, 2005 01:40 PM
Hormones are potent regulators of the most intricate biochemical functions involved in our metabolism, growth, development, emotion and behavior. For our bodies to function properly, our hormones must be in balance with one another. But aging, stress and environmental factors can contribute to hormonal imbalances, with serious impact on our well-being. Today, science has rediscovered a beneficial hormone with the capacity to reduce stress, fatigue and support mental alertness. This hormone is broad – spectrum in its influences - with the ability to balance the levels of other hormones in our bodies. Unfortunately, our production of this hormone declines as we grow older - suggesting the desirability of supplementation. Introducing: Source Naturals PREGNENOLONE.
A Wide Range of Beneficial Properties
Pregnenolone - a hormone produced from cholesterol in our adrenal glands, liver, skin, testicles, ovaries, and brain - was the subject of intense interest in the 1940’s. Some of the earliest studies, performed by well-known researcher Hans Selye, found it to be helpful in reducing stress and fatigue. Additional studies were conducted throughout the decade, with positive results. Pregnenolone supplementation was found to benefit people who were under excessive stress. It also was reported to support joint and tissue function and to contribute to skin elasticity. Pregnenolone is believed to affect stress levels through its influence on the adrenal glands, which produce more steroid hormones when people are under stress. Pregnenolone may also affect brain chemistry in beneficial ways. It has been found to inhibit the GABA receptors in brain cells - which may result in increased mental alertness. It may also stimulate the NMDA (N-methyl-D-Aspartate) receptors, which play an important role in regulating synapses, thus influencing learning and memory.
Pregnenolone: The Unique Hormone
Much of the current interest in pregnenolone is related to its role as “the grandmother of all steroid hormones.” Pregnenolone is the starting point from which all steroid hormones are manufactured in our bodies. As a “hormone balancer,” it has the capacity to increase the levels of steroid hormones that are deficient in our bodies and to reduce the levels of excess circulating hormones. Some scientists believe pregnenolone is converted into other hormones only as they are needed by our bodies. The conversion of pregnenolone follows different pathways, depending upon cellular requirements. Pregnenolone may be converted into DHEA (dehydroepiandrosterone), which in turn can be changed into androgens (including testosterone), estrogens and other steroids; or, it may be converted into any or all of a chain of hormones including progesterone, corticosterone, and aldosterone. These characteristics make pregnenolone unique. Because cells may only convert pregnenolone into other hormones on an “as needed” basis, pregnenolone may correct imbalances in the levels of some hormones, without affecting others. This is a great advantage over steroid hormones like DHEA, which may create excess estrogen and testosterone. Pregnenolone is also distinctive because of the innumerable bodily activities it can influence. As a steroid hormone precursor, it is believed to be involved in every biochemical action exhibited by any steroid hormone. This means it may impact memory, mental alertness, stress responses, female reproductive cycles, the body’s natural defenses, and joint and tissue function. With such a wide spectrum of involvement, the potential uses of pregnenolone could be boundless. Source Naturals PREGNENOLONE is available in 10 mg sublinguals and tablets, as well as in 25 mg tablets. All potencies are sold in 60 and 120 tablet bottles.
Chem-Defense - Fight Chemical sensitivity ...
June 01, 2005 10:21 AM
CHEMICAL SENSITIVITY IS REAL.
COURTESY OF THE INDUSTRIAL REVOLUTION, OUR ENVIRONMENT HAS BECOME A STEW OF FOREIGN CHEMICALS. For some people suffering the malaise, lack of focus, and drained feeling associated with chemical sensitivities, home is the only sanctuary from this onslaught. For others, not even home is safe. We at Source Naturals take this threat very seriously. That’s why we created CHEM-DEFENSE.
Source Naturals’ CHEM-DEFENSE is a potent combination of Molybdenum, Glutathione, and Coenzymated B-2, nutrients which research has shown may help break down and dispel harmful chemicals from the body. And CHEM-DEFENSE is sublingual — it dissolves under the tongue so it goes directly into your bloodstream, where it can be delivered to your system, fast.
major problem has hit America in the late 20th century that is more far reaching than most people are aware — chemical sensitivity. In fact, some studies indicate that 1 out of 3 Americans may be afflicted with chemical sensitivities. In the past century, modern organic chemistry has synthesized and released into the world an estimated 300,000 xenobiotic (foreign to our normal biology) chemicals. The food processing and food growing industries put an approximate 10,000 xenobiotic chemicals into our food supply alone. These chemicals can be found in common items such as cleaning fluids, drycleaning compounds, glues, cigarette smoke, perfume, building materials and processed foods. Chemical sensitivity is the result of impairment or inadequacy of the body’s natural detoxification systems, allowing excessive levels of harmful, xenobiotic chemicals to accumulate in the body, and the results are often devastating. In sensitive people, artificial chemicals can cause an incredible range of problems: “fogginess” and lack of focus, emotional distress, fatigue, and more. The parts of the body that are most affected can vary from person to person. Some of the worst offenders are the aldehydes. The most infamous of these is formaldehyde (found in such widely used items as permanent press clothing, particle board, paints and upholsteries). The other common culprit is acetaldehyde (produced by Candida overgrowth or from alcohol consumption).
The Secret to CHEM-DEFENSE’S Power is Molybdenum
Fortunately, nature has provided the body with a special aldehyde detoxification pathway: an enzyme called aldehyde oxidase (ADO). ADO is activated by one of the coenzyme forms of Vitamin B2, Flavin Adenine Dinucleotide (FAD), and the trace mineral Molybdenum. Unfortunately, this enzymatic pathway can become impaired due to overexposure to foreign chemicals. In addition, aging, nutritional deficiencies, genetics and general poor health can greatly diminish the body’s production of these enzymes, causing a toxic buildup of aldehydes, leaving many individuals vulnerable. Current nutritional research has revealed that supplementing the diet with Molybdenum and Coenzyme B-2, both found in CHEM-DEFENSE, can increase levels of the important enzyme ADO, helping to dispel toxins from the body. A study published in the Townsend Letter for Doctors confirms the benefits of a sublingually administered 300 mcg dose (100 mcg three times a day) of Molybdenum. It was found that on the average, about 50-65% of the various symptoms of chemical sensitivity — including fogginess and other discomforts — were alleviated at least to some degree. Molybdenum is also important for several other enzymes, including xanthine oxidase, and most importantly, sulfite oxidase. Sulfite oxidase is responsible for breaking down sulfites, chemicals widely used as preservatives in wines, salad bars, produce, and other foods. Sulfites are a common culprit in chemical sensitivity reactions. In fact, by the 1980’s, it was conservatively estimated that 5,000,000 (five million) Americans were sensitive to sulfites and experienced discomfort upon ingestion. Sulfite oxidase is also important in the sulfation of various compounds, especially in the brain. This is particularly important, as the brain is often dramatically affected during bouts of chemical sensitivity. According to the Nutrition Desk Reference, the amount of Molybdenum required daily for people is 100 mcg to 500 mcg. It also states that the amount of Molybdenum in food can vary tremendously, depending on crop soil levels. Low levels are not at all uncommon, and they are lessened even further by commercial farming practices that utilize synthetic fertilizers which do not put Molybdenum back into the soil. The result? The typical American diet does not provide adequate Molybdenum. The form of Molybdenum included in CHEM-DEFENSE is Molybdenum Aspartate-Citrate, Molybdenum bound to the cellular metabolites Aspartic Acid and Citric Acid. This has been shown to be the most bioactive form available by experts in mineral metabolism.
Glutathione in its Most Bioavailable Form
Ultimately, the one organ that must cope with and attempt to relieve the body of toxic chemicals is the liver, often referred to by nutritionists as “the body’s most overburdened organ.” To accomplish this, the liver must rely heavily on Glutathione, a tripeptide (three amino acids bound together). The Glutathione in CHEM-DEFENSE will help the liver to produce adequate levels of the important enzymes glutathione peroxidase (GSHpx) and glutathione S-transferase (GSH-S), enzymes that are essential for breaking down and disposing of foreign chemicals in the body. Glutathione peroxidase (GSHpx) helps to break down hydrogen peroxide, a medium-level toxin which is found in many xenobiotic chemicals. GSHpx also prevents cell damage caused by fatty acid oxidation, which threatens the integrity of cell membranes. Glutathione is very fragile. In fact, when taken orally, it is often destroyed by protein-digesting enzymes in the stomach. As CHEM-DEFENSE is in sublingual form, it bypasses the digestive process and goes straight into the bloodstream, allowing for maximum activity.
Coenzyme B2 — The “Recycling” Nutrient
Once Glutathione is used in the body for its detoxification functions, it becomes oxidized Glutathione, meaning it has been “used up.” Fortunately, the human body can “recycle” oxidized Glutathione and return it to its beneficial reduced (active) state. This process is made possible by a coenzyme form of Vitamin B2 (FAD), which is present in CHEM-DEFENSE.
Sublingual Delivery for Maximum Benefit
Many nutrients, when taken orally, are never completely absorbed into the bloodstream, or not absorbed at all! Because this formula is in sublingual form, the nutrients in CHEM-DEFENSE are absorbed directly into the bloodstream through the blood vessels under the tongue and in the cheeks, assuring maximum bioavailability and benefit. In America today, as foreign chemicals continue to be released into the environment on an uncontrolled basis, people continue to experience chemical sensitivities for which there appears to be no solution. Now there is. Source Naturals CHEM-DEFENSE combines the most bioavailable forms of key antioxidant nutrients that are not only powerful in and of themselves, but work together synergistically to address the problems associated with chemical sensitivities. As with all of their other products, Source Naturals has taken special care to create a product that is all natural, hypo-allergenic, and sugarfree. CHEM-DEFENSE sublingual is available in two delicious flavors — natural peppermint, and for people on homeopathic regimens who prefer an alternative to peppermint, natural orange flavor. Let’s face it — life in the modern world is a battle for your health. Arm yourself with a powerful weapon: Source Naturals CHEM-DEFENSE.
Attentive Child - Enhances Mental Concentration ...
May 31, 2005 05:14 PM
Most children are creative, energetic and spontaneous, but sometimes they don’t focus on requested activities. Sometimes kids find it difficult to apply themselves to the task at hand. Your child’s brain also may work differently than most people’s brains— just like the 5% of the population that is left-handed. Most people think an ultra-active child means an active brain, but active children may actually need a boost in brain metabolism. Source Naturals ATTENTIVE CHILD is a Bio-Aligned Formula™ designed to address the multiple systems that affect children’s ability to focus: neurotransmitters and brain metabolism, nerve cell communication, antioxidant defense, and essential fatty acid metabolism.
Comprehensive Brain Support
Parents are looking for a safe and natural product to support their children’s ability to focus. Source Naturals studied the research and created an experiential formula, based on the latest breakthroughs in cerebral and nervous system biochemistry. Each ingredient in ATTENTIVE CHILD plays a role in brain and nervous system structure or functioning, or is involved in important biochemical pathways. DMAE, a substance normally found in the brain, boosts brain metabolism and has been shown to enhance concentration. L-Aspartate is an amino acid neurotransmitter that stimulates brain activity. Research has shown that some ultra-active children may have special dietary needs for magnesium, zinc and DHA (docosahexaenoic acid). Magnesium is necessary for the transmission of nerve signals, and, along with zinc, for the processing of essential fatty acids into other vital biochemicals. DHA is an essential fatty acid that is very important for cerebral development and effective communication between nerve cells in the brain. Lecithin contains four phospholipids—fatty acid building-block molecules in nerve cell membranes. Phosphatidylserine, in particular, is vital in nerve cell communication and the electrical activity of the brain. Grape seed extract is a plant-derived antioxidant that protects the integrity of fatty acids in nerve cell membranes.
ATTENTIVE DHA™ in Tiny Kid Caps™
The ATTENTIVE CHILD formula can be supplemented with additional DHA. ATTENTIVE DHA Kid Caps are available in easy-to-swallow, small oval softgels, each containing 100 mg of DHA. For children who can’t swallow caps, simply pierce the gel and mix the oil with food. Sweeteners with Low Impact on Blood Sugar The delicious sweetand- tart taste in ATTENTIVE CHILD wafers comes from natural flavors, specially manufactured without sugar for Source Naturals. Unless specified, most flavors in other products contain maltodextrin, a sugar with a high glycemic index. The ATTENTIVE CHILD wafer itself is sweetened with crystalline fructose (natural fruit sugar) and xylitol (a naturally occurring sweetening agent found in many fruits and vegetables). These select natural sweeteners have a very low glycemic index—so ATTENTIVE CHILD will taste great to your child, but have little effect on blood sugar levels. We recommend carefully reviewing the labels of other products. They may contain honey, glucose, sucrose, maltodextrin, and maltose—all of which have moderate-tohigh glycemic indexes. In addition, maple sugar, molasses, malt syrup, rice syrup, and beet sugar contain varying amounts of high-glycemic-index sugars, which can set off blood sugar fluctuations that may affect concentration. Beware of children’s nutritional bars designed to enhance focus and concentration. Most have over 20 grams of sugar per bar. In contrast, each serving of ATTENTIVE CHILD contains only two grams of crystalline fructose, which has little effect on blood sugar.
Glycemic Index of Various Sweeteners
The glycemic index is a ranking of foods based on their immediate effect on blood glucose levels. It measures how much your blood glucose increases over a period of two or three hours after intake. The higher the glycemic index (GI), the greater the fluctuations in blood sugar. Sweetener Glycemic Index†
*sweeteners used in ATTENTIVE CHILD ™ †based on rate of 100 for glucose ††for information, see website www.wcommerce.com
Lifestyle Strategies for Your Child
You can help your child concentrate on schoolwork, chores and other challenges. Start with ATTENTIVE CHILD and ATTENTIVE DHA, and then incorporate a healthy lifestyle and nutrition routine.
Have your child’s overall health checked by a welltrained holistic health care professional, such as a naturopathic physician. It is particularly important to examine the functioning of your child’s thyroid gland (the master regulator of the body’s metabolism, which influences mood and energy level), and blood sugar metabolism (the brain depends on a steady supply of glucose to function properly, particularly when you are trying to concentrate).
Nutritional Health: Feeding the Brain
Help your child maintain a steady supply of energy and brain fuel by providing a balanced diet. Small, frequent meals are preferable since they dispense a steady level of glucose to the brain. Include foods high in the amino acid tyrosine, a precursor to neurotransmitters that support an alert state. It is found in protein foods, such as meat, poultry, beans, tofu, lentils and seafood. Also include complex carbohydrates such as whole grains, fruits and vegetables, which are metabolized slowly and yield a steady supply of glucose. The simple sugars found in candy, cookies, sodas and other processed foods can lead to a rapid rise in blood sugar levels, followed by an abrupt decline, and should be discouraged. It is important to include essential fatty acids, especially omega-3 fatty acids, which are abundant in the brain and essential for its development and normal functioning. Supplement with ATTENTIVE DHA, and encourage your child to eat cold-water fish, such as salmon. Avoid the hydrogenated fats found in processed foods and margarine, as well as chemicals and food additives. A nutrition program consisting of fresh, unprocessed natural foods is the healthiest choice for everyone.
Some experts believe extended time watching TV and playing video games does not support optimal health or school performance. EEG studies have shown that these activities decrease brain activity rather than activating the brain. Encourage your child to spend time in outdoor physical recreation and in creative, challenging activities.
Supplement with ATTENTIVE CHILD and ATTENTIVE DHA
ATTENTIVE CHILD is available in bottles of 30 & 60 chewable wafers. ATTENTIVE DHA Kid Caps (algal-source Neuromins®) are available in 30- & 60-softgel bottles. References Amen, D. Windows into the....Mind. Fairfield, CA: MindWorks Press, 1997. Foster-Powell, K. & Miller, J.B. 1995, International tables of glycemic index. Am J Clin Nutr. 62:871S-93S. Natah, S.S. et al. 1997. Metabolic response to lactitol and xylitol in healthy men. Am J Clin Nutr. Apr; 65(4):947-50. Schmidt, Michael. Smart Fats. Berkeley: Frog, Ltd., 1997. Sears, William. Boston: Little, Brown & Co., 1998.