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Want To Look And Feel Your Best? Stop Counting Calories
April 17, 2017 06:44 AM
Everyone wants that sexy, slim beach body, especially as the warmer summer months are coming and the beach is calling. However, most people do not know the best way to achieve their goals. One of the simple things you can do to start on your way to these goals is to stop counting up every calories, to put that calculator away that you use to add up the caloric contact of everything that you eat.
Read more: Want To Look And Feel Your Best? Stop Counting Calories
4 Types of Headaches You Should Never Ignore
February 16, 2017 10:19 AM
We all get headaches from time to time. Sometimes they are self-induced through stress, diet or lack of movement and other times they signal that something else is might be going on inside our bodies. Do not ignore your Beaches if they are sharp pains or take place in certain parts of the headhttps://www.youtube.com/watch?v=kVpCCFbT5XY
"We all get headaches from time to time. Sometimes they are self-induced through stress, diet or lack of movement and other times they signal that something else is might be going on inside our bodies."
4 Ways Food Can Fight Muscle Soreness
December 10, 2016 04:59 PM
These tears, coupled with inflammation and temporary muscle aches and pains are commonly referred to as Delayed Onset Muscle Soreness or DOMS. Typically, DOMS increases after exercise and peaks 24 to 72 hours later. Although more research is needed, proposed strategies for reducing exercise-induced inflammation, pain, soreness, and weakness include cold or hot water immersion, cryotherapy, and compression clothing. Non-steroidal anti-inflammatory drugs are the most commonly used drugs by athletes of all levels to reduce exercise-mediated inflammation and soreness.
"Several studies have highlighted the importance of recovery following prolonged or high-intensity exercise (like marathons, ultra-marathons, and triathlons)."
Tick bites can cause life-threatening allergic reactions to red meat
November 20, 2016 05:09 PM
There may be a new epidemic of tick-born disease on the rise. The U.S. and Australia have been seeing an increase in the number of people reporting that they can no longer eat red meats after being bitten by certain ticks. It is believed that some people are more sensitive to proteins in the saliva of the bugs, making allergic to red meats. In some cases, patients have gone into anaphylactic shock. This condition is more common in Australia than the United States.
"For a growing number of people, it is no longer possible to eat any red meat because they have developed an allergy to it after being bitten by a tick."
Fight Inflammation With Herbs from Planetary Herbals
June 02, 2010 04:39 PM
Our modern lives have untold benefits, as well as challenges. Our dependence on man-made toxic chemicals, junk food, nutrient imbalanced diets, and our stressful, sedentary lifestyles can alter our biochemical metabolism and affect our health.
These lifestyles and environmental change can challenge immune health, so that the various components of the immune system are not able to carry out their protective functions. Or our immune systems can go into overdrive, often leading to a state called metabolic inflammation.
A Powerful Herbal Blend
Inflamma-Care is a potent, herbal response to the metabolic inflammation that can result from inappropriate immune response. The main component of inflama-care is the rhizome of the curcuma spicies, long used as a spice in India. Known worldwide as turmeric (curcuma longa), it acts as an anti-inflammatory by inhibiting the activities of cytokines – inflammation messengers.
This world-renowned spice is supported by boswellia, which inhibits pro-inflammatory enzymes, and ginger an antioxidant that inhibits prostaglandin and leukotriene biosynthesis. Other herbs in the formula that inhibit inflammatory action include willow bark, Chinese skullcap, corydalis, holy basil, and hops.
Inflama-care also contains systemic enzymes to clear and protect the arteries and circulatory system. Systemic enzymes like bromelain and papain cleanse the bloodstream and enable the blood to flow smoothly. A free-flowing bloodstream helps the body by circulating important nutrients to the cells while clearing the body of wastes.
Immune Activating Mushroom
Planetary Herbals also offers you new Full Spectrum Chaga in 1000mg tablets and a 1:4 liquid extract. Preliminary studies suggest that chaga triggers immune responses and protects the cells with antioxidant activity.
Chaga is a mushroom that is found attached to trees like birch, alder, Beach, and other hardwoods, throughout the northern latitudes. A polyphore, the mushroom looks somewhat like coal – a brownish black mass often seen in tree trunks. In China, Siberia, Finland, Japan, Poland and North America, ancient and native peoples have long known the benefits of chaga. In an acient treaties, the Chinese monk shen nog declared in 100 BC that chaga is “a precious gift of nature.”
In modern research, chaga has been shown to have 215 phytonutrients, including 29 beta-glucans. Chaga also absorbs a nutrient from the outer birch tree bark: betulin, a natural anti-inflammatory. Among the components in chaga are triterpenes, sterols, beta-glucans, flavonoids, melanins, polyphenols, saponins, lignin, amino acids, vitamins, minerals, and fiber. This fascinating combination of nutrients is being studied worldwide.
The PhytoDynamic Difference
Both inflama-care and full spectrum chaga are formulated with a profound understanding of the ways in which plant compounds interact with human physiology. Planetary Herbals phytodynamic principles draw on herbal tradition, scientific research, and a level of clinical expertise unmatched in the natural products industry. The result: herbal products unsurpassed for quality and consumer satisfaction.
Noni Fruit Extract
November 22, 2008 09:34 AM
Tahitian Noni juice can promote a healthy body in many ways. These Noni benefits are conferred by the phytochemicals contained within the fruit pulp, but before discussing the benefits of Noni let's first have a look at what it actually is.
Morinda citrifolia is also known as the Indian or Beach mulberry tree, and is a member of Rubiaceae family. Although it originated in Southeast Asia, it has spread all the way to French Polynesia and the Dominican Republic. It is mainly cultivated in Tahiti for its fruit, known as cheese fruit or Noni fruit.
Although it is a staple food in some areas of the Pacific, it has a pungent smell and a bitter taste, and often eaten either raw or cooked only in times of famine. However, the fruit is particularly rich in phytonutrients, and many people swear by the Noni benefits it to maintain a glowing healthy body, free from disease and many of the health problems from which most people suffer.
The strange thing about it is the taste: you would not drink Tahitian Noni juice by choice, nor eat the fruit, so how were these Noni health benefits discovered? Hunger likely explains it: those forced to eat it through hunger were likely the lucky ones, who actually ate a nutritional diet even though they were eating a fruit normally eaten only in times of famine.
Among the conditions that Noni fruit is believed to protect you from are cardiovascular disease, high cholesterol levels, asthma, cholesterol, strokes, migraines, a weak immune system, arthritis and some cancers. Many of these conditions should give you a clue as to the nature of the phytochemicals contained within the fruit, since most of them involve free radical attack and immune system response.
Prior to examining thee diseases and conditions in detail, let's have a look at the chemicals the fruit has been established to contain. It is rich in dietary fiber, offering 100% of the Dietary Reference Intakes of the Institute of Medicine for each 100g serving, and also contains enough carbohydrate to meet 55% of you DTI needs. However, that is just the start.
The Noni pulp powder contains ten times the DRI of Vitamin C, and large quantities of Vitamin B3 niacin), potassium and iron. The Tahitian Noni juice itself contains few nutrients, and only the Vitamin C is retained to any useful level. It is therefore the pulp powder that offers the major nutritional benefit. In fact, because it has to be pasteurized at high temperature to meet regulations the for liquid product, Noni juice loses most of its nutritional content, and even the 31% Vitamin C content is surprising since that too is destroyed at high temperatures.
It is the high phytochemical content of Noni powder that renders it such an important supplement, and a scan down the following components will give you an idea of how the fruit got its reputation. The known Noni benefits are obtained from:
Lignans: these are phytoestrogens that have been reported to offer a reduced risk of ovarian and breast cancers, osteoporosis and also cardiovascular disease. They possess antioxidant properties and although reports as to their effectiveness are varied, they appear to have beneficial health effects.
Flavanoids: These are phenolics, including asperulodisic acid and rutin. The former is believed to be effective against certain cancers, while rutin, also contained in buckwheat, is a strong antioxidant that strengthens capillaries, and also helps to prevent atherosclerosis and heart disease.
Catechin and epicatechin: strong antioxidants that help prevent heart disease, strokes, diabetes and cancers. It also protects your skin against the harmful effects of the ultra-violet component of the sun's rays. Catechin is a form of flavanoid, and one of the more powerful of the antioxidants needed to destroy the free radicals that would otherwise ravage your body through the destruction of your body cells.
B-Sitosterol: a plant sterol that is believed to reduce the cholesterol in your blood, but still requires scientific proof, even though there is plenty of evidence to support its effect. Plant sterols are the basis of the cholesterol-lowering yoghurt drinks that you can but in your local supermarket.
This list is not exclusive, and there are several other phytochemicals found in Noni pulp powder that are believed to confer significant health benefits, but that are still seeking scientific support. The fact that such support has yet to be provided is not a reason to doubt their effectiveness, although the above benefits are sufficient to justify the reputation of this nutritional supplement that few have heard about.
There have been only around 110 reports on Noni research since the 1950s, so it is not surprising that the scientific proof is weak, although of these around 100 have appeared since the year 2000. Don't forget that there was no proof for the effectiveness of penicillin until it was discovered!
Even the biochemistry of the components of Tahitian Noni juice, such as the polysaccharides not mentioned in the above list, is in the early stages of research, and an increasing number of traditional remedies are being found to have a valid scientific and medical basis. These polysaccharides are a form of dietary fiber with probiotic properties that can be fermented by bacteria in the gut to form short chain fatty acids that possess many beneficial health properties.
Take the heterocyclic iridoids, for example. These are unknown to most people, yet they are found in many plants that have extensive medicinal properties, and might be responsible for many of them. They appear to possess anti-inflammatory, antiviral and antispasmodic properties, and support the cardiovascular system, the immune system and help to maintain a healthy blood sugar level. These are also contained in Noni pulp powder.
Another component of Noni fruit that most people have not heard of is damnacanthal. This inhibits certain tyrosine kinesis that basically have a controlling effect on the division of body cells. They particularly inhibit the Ras genes, responsible for some cancers due to uncontrolled cell division. Damnacanthal can prevent Ras genes from causing these cancers.
There are many more benefits that Tahitian Noni juice, or particularly the powdered Noni pulp, can confer, and it is recommended that it be taken as a supplement by anybody needing a general health tonic since it possesses such a wide variety of beneficial properties. The Noni benefits which those that use it enjoy area available to everyone, even though it is one of the lesser known of the beneficial health supplements.
An Interview with Congressman Sam Farr, Representing California’s Central Coast.
May 30, 2006 02:36 PM
Ambassador to Health Profile
An Interview with Congressman Sam Farr, Representing California’s Central Coast.
Congressman Sam Farr, a fifth-generation Californian, represents the state’s beautiful central coast. His district encompasses the length of the big Sur coastline in Monterey County, the Monterey Bay National Marine Sanctuary, the Salinas Valley “Salad bowl,” the redwoods, mountains and Beaches of Santa Cruz County, and the majestic rural landscape of San Benito County. The health and wealth of this region has been strengthened by Rep. Farr’s focus on the environment, education and the economy. Rep. Farr was raised in Carmel, California and graduated from Willamette University with a BS in biology. He later attended the Monterey Institute of International Studies and the University of Santa Clara. He is fluent in Spanish. As a tough advocate for the health food industry, he has lobbied for strict federal organic standards.
Todd: Congressman Farr, thank you for taking the time to speak with us! Id also like to thank you for all the great things you’ve done for our community, form funding marine sanctuaries and authoring the Ocean’s Act to expanding Pinnacles national Monument. The League of Conservation Voters and others have recognized you as an “Environmental Hero”. And, you’ve worked hard to support the economic vitality of central coast’s $3 billion agriculture industry which includes a substantial organic segment. Our backyard here is also the home of a robust group of nutritional supplement manufacturers. An estimated 187 million Americans are currently taking dietary supplements as part of their daily healthy diet. In California, we’ve got 792 natural product manufacturers and distributors. Where do you stand on the state of our industry?
Congressman Farr: Well, thank you for the introduction and for asking to talk to me about nutritional supplement issues. I am very supportive of this industry and include myself in the 187 million Americans taking dietary supplements. I think supplements offer many safe and viable tools to maintain your health. The continued growth of this industry is an indication of both consumer confidence in the products and the products’ ability to fill the gaps where conventional medical care falls short.
Todd: It is estimated that by 2030, more than 70 million Americans will be over the age of 65 and the cost of health care could reach $16 Trillion per year. A recent study by the Lewin Group showed that by taking certain dietary supplements, seniors can lead healthier, more productive, independent lives while saving billions in reduced hospitalizations and physician services. Do you share our view that a Wellness Revolution is needed to counter the dilemma of an aging population versus shrinking health care support in the future?
Congressman Farr: Our health care system is definitely facing a challenge, especially as the Baby Boomers hit their 60’s and Americans are living longer than ever before. As a Baby Boomer myself, I am well aware of America’s aging population and the impact that will likely have not only on our social institutions but also our fiscal well-being. I agree that dietary supplements do play and will play an even larger role in the future as more seniors look for a way to augment their diets in order to stay healthy and active longer than past generations.
Todd: Our industry is regulated by DSHEA (the Dietary Supplement Health and Education Act), which was passed unanimously by Congress in 1994 to create a reasonable regulatory framework for access to, information about, dietary supplements. But many say that the FDA and DSHEA weren’t adequately funded to do the job as tasked. “Supplements are unregulated” is a false argument we sometimes hear. To ensure that the FDA is able to carry out the law as Congress intended, Representatives Dan Burton (R-Ind.) and Frank Pallone (D-N.J.) introduced H.R. 2485, the DSHEA Full Implementation and Enforcement Act of 2005. Did you support this bill and where does it stand today?
Congressman Farr: I think the DSHEA is a critical law and was proud to support it when Congress considered it in 1993 and 1994. I would certainly support H.R. 2485 if it came up for a vote in Congress. Unfortunately this bill has not moved since it was first introduced and referred to the Subcommittee on health in the house energy and commerce committee. Since this is an election year we have a tight schedule with only about 60 legislative days scheduled before we adjourn. That means it’s likely Congress will only finalize bills such as the appropriation bills that fund government before adjournment.
Todd: Our business climate has included some valid and rigorous challenges to improve our industry, from good manufacturing practices (GMP), to allergy labeling, to implications of Prop-65 in California. It’s disconcerting that a new bill, H.R. 3156 The Dietary Supplement Access and Awareness Act would try to capitalize on misconceptions about the industry. In an era of declining health care and declining insurance coverage, this bill would regulate supplements as prescription drugs. Among other things, it would also require adverse event reports to be turned over to the FDA, even though other foods, including those with identical ingredients, do not have the same requirements. This has the potential to be the next Prop-65-like Lawsuit mill. The result of H.R. 3156 would be chilling. It will knock smaller producers out of the market. It will result in higher prices for all supplements. It will decrease the availability of health-giving supplements to the public. What’s your feeling on this?
Congressman Farr: I am similarly concerned about H.R. 3156 and would oppose it if it came up for a vote in Congress. Like H.R. 2485, this legislation has been referred to a subcommittee on Health in the House Energy and Commerce Committee without any further action. The supplement industry has worked in good faith with the FDA since passage of DSHEA and H.R. 3156 would re-invent a wheel that isn’t needed. Instead, adequate funding as proposed in H.R. 2485 would provide ample oversight for the industry.
Todd: According to a recent study, 72% of the general population believe the government should fund more research on health benefits of nutritional supplements. Do you agreen and what can be done to meet this need?
Congressman Farr: I definitely agree that the federal government should play a bigger role in support of research regarding the health benefits of nutritional supplements. As a member of the House Appropriation Committee, I sit on the subcommittee that has jurisdiction over the FDA’s budget and I know the tight fiscal restraints the agency is under. I’ve worked with my colleagues to provide adequate funding, but it’s an uphill battle especially when we’re in a “robbing Peter to pay Paul” kind of situation. I recommend that people within the industry organize and use your consumer base to actively lobby Congress for additional funds. I’m fond of reminding people that the squeaky wheel gets grease – so let every Congress member and Senator know how much this issue matters to you.
Todd: When there is overwhelming scientific evidence that nutritional supplements provides relief for a disease condition, it currently takes a lawsuit to get the FDA to relent and allow the claim. Even then, the FDA strictly limits the claim and requires a disclaimer that does more harm than good in communicating this important information to the public. There is a new bill, H.R. 4282, The Health Freedom Protection Act that would end FDA and FTC censorship of health information. As an example, the 50% of all adult males who suffer from an enlarged prostate could receive relief from that condition by consuming a simple and safe ingredient, saw palmetto derived from the fruit of the dwarf American palm tree. The FDA censors that information. The public deserves a better opportunity to be informed about omega-3 EFA and heart disease, folic acid and birth defects, phosphatidylserine and cognitive impairment. Do you agree and do you support this bill?
Congressman Farr: I agree the public needs to access to the best information possible so they can make well informed choices about their health. I likely would support H.R. 4282 if it came up for a vote in Congress. Unfortunately this bill is in a similar situation as other we’ve mentioned in this interview – and again because of the tight schedule of an election year, it’s unlikely action will happen this year.
Todd: According to the barometer study, 85% of the US population is currently using some type of dietary supplement. Do you? Looking at your busy schedule from co-chairing the House Oceans Caucus to your seat on the Travel and Tourism Caucus, you are one busy congressman! Are you popping nutritional supplements please tell us!
Congressman Farr: I do take some nutritional supplements, though they vary and since Ginkgo Biloba isn’t among them I cant remember their names off-hand! One product I do use faithfully is Airborne to help me combat germs and colds that I might get from sitting on an airplane. But, like many Americans my life is over-scheduled and combined with the amount of air-travel I do, I find nutritional supplements helpful as I try to stay healthy despite my hectic lifestyle.
Todd: Thank you Congressman Farr! Live long and prosper!
DSEA Release of Health/Cost Impact Study Conducted by the Lewin Group, Initial Results, Wash DC; Nov. 2, 2005
NNFA database. Adam.F on 3-15-06.
DSEA Nutritional Supplement Barometer Study, 2005 Report, Prepared by the Natural Marketing Institute (NMI).
Todd Williams; Source Naturals Marketing Programs Manager.
NEW PRODUCT ANNOUNCEMENT - Hyaluronic Joint Complex
August 03, 2005 01:27 PM
NEW PRODUCT ANNOUNCEMENT
Hyaluronic Joint Complex ™ with Glucosamine, Chondroitin and MSM
The Next Generation in Joint Formulas!
2 tablets contain:
BioCell Collagen is a trademark of Biocell Technology LLC, Newport Beach, California USA (US patent 6,025,327 - other USA and foreign patents pending). OptiMSM is a trademark of Cardinal Nutrition.
Suggested Use: 2 tablets twice daily, or as recommended by your health care professional.
Say Goodbye to Headaches
June 13, 2005 07:25 PM
Say Goodbye to Headaches by Susan Weiner Energy Times, December 8, 1999
What's in a name? A headache by any other name hurts just as much. But categorizing your headache can be as overwhelming as finding an obscure breakfast cereal at the supermarket. Medical folks pigeonhole headaches as tension headaches, allergy headaches, morning headaches and sinus headaches, plus the organic, migraine, cluster, trauma, TMJ, eyestrain, rebound, exertion, hormonal and muscle tension varieties. You may also suffer the self-induced hangover and toxicity headaches.
Americans are no strangers to self-medication, and as a society we battle these headaches by consuming nearly 80 billion tablets of aspirin each year, about 20 million aspirins a day, according to Burton Goldberg, co-author of An Alternative Medicine Definitive Guide to Headaches (Future Medicine Publishing). And while we drown ourselves in over-the-counter and powerful prescription products, our tolerance, just like a drug addict's, grows. So what begins as a twodose headache slowly evolves into three, four or five doses, until you realize that no dosage can make your headache go away.
Unless you're fond of medieval practices such as ritualistic healings and bloodletting, drugs seem the only answer to headache misery. But even modern medicine has been unable to solve headaches. Rather than a cure, medications provide only temporary relief, and even that isn't guaranteed. Additionally, over-reliance on medications can lead to chronic head pain. According to Goldberg, rebound headaches often result from the consumption and withdrawal of drugs.
Halt Your Headaches
Rather than strive to simply eliminate headache pain, why not identify the underlying cause and prevent the headache? Almost always, every type of headache results from a health or lifestyle-related activity. In an ideal world, the best approach would be to eliminate the tensions, stress, frustrations, anger, insufficient sleep, excessive drinking and poor diet that contribute to your headaches. For better or for worse, however, you can't always: a. quit your job; b. ask your spouse to leave; c. sit on the Beach all day; or d. all of the above. But you can make appropriate lifestyle changes and learn to express suppressed feelings.
This approach, lifestyle modification, is a treatment program based on a Loma Linda University study, originally published in Medical Hypothesis and the Journal of Women's Health and Gender-Based Medicine and later explained in No More Headaches, No More Migraines: A Proven Approach to Preventing Headaches and Migraines by Zuzana Bic, DrPH and L. Francis Bic, PhD (Avery). The program, conducted on a group diagnosed with chronic migraines, dramatically decreased the frequency, intensity and duration of headaches in nine of 10 headache sufferers. Rather than demand radical life changes, the lifestyle modification program introduces gradual changes in three specific areas: nutrition, exercise and understanding stress. The study doesn't expect you to change your entire diet, join a gym and eliminate everything that triggers stress, but teaches techniques to make subtle lifestyle changes and reduce the impact of daily stress. These same techniques can also improve sleep patterns, a factor known to affect headaches. The lifestyle modification approach clarifies that while very few headaches directly result from existing acute conditions, recurring headaches often derive from a larger lifestyle factor. If these issues are ignored, the body's natural defense mechanisms may kick into overdrive and become exhausted, leaving you susceptible to other chronic diseases. By finding and eliminating the cause of your headaches, you may be saving yourself from other eventual illnesses.
Willing to make some lifestyle changes and step away from medications? Try these remedies, courtesy of Nature's Pharmacy by Lynn Paige Walker, PharmD and Ellen Hodgson Brown, JD (Prentice-Hall).
For simple headaches, start with relaxation and neck stretches. Or try rubbing your forehead with peppermint oil, a natural antispasmodic and diuretic shown in German research to be as effective as acetaminophen in easing tension headaches.
Never underestimate the old-fashioned ice pack to the forehead as an effective treatment that works by constricting the swollen blood vessels that cause your head to ache. If the ice pack isn't enough, try putting your arms in icy water up to your elbows to constrict additional blood vessels. But if it's a sinus headache you're fighting, take the opposite approach and try hot compresses.
The herbal, and original, form of aspirin is white willow bark. Used by Chinese practitioners 2,500 years ago, it contains salicin, nearly the same pain reliever found in aspirin. Other herbal aspirins include meadowsweet tea, just as effective as aspirin with few side effects. For migraines, Walker and Brown recommend feverfew and magnesium supplements, which reduce nerve excitability and migraine susceptibility. In fact, individuals with frequent headaches have been found to have low brain and tissue magnesium, says Julian Whitaker, MD, author of Julian Whitaker's Guide to Natural Healing (Prima). For all headaches, Goldberg suggests essential fatty acid supplementation with evening primrose oil (EPO), which improves circulation, helps regulate inflammation and relieves pain.
The Curse of the Migraine
Migraines, a debilitating headache distinguished by a throbbing pain, may be humanity's oldest malady. The name is derived from the word the Greek physician Galen used to describe the disorder in 200 A.D. Six-thousand-year-old Sumerian writings refer to the ravages of migraines, and prehistoric skeletons bear testimony to a crude form of trephination-holes chiseled in skulls to allow the escape of pain-creating demons, according to Lifetime Encyclopedia of Natural Remedies by Myra Cameron (Parker Publishing).
In the common migraine, throbbing pain develops gradually from distended veins around the brain and may be accompanied by nausea, vomiting and sensitivity to light. These miseries can be preceded by 15 to 90 minutes of an "aura," which includes visual disturbances, distorted perception, hallucinations, flashes of light and temporary loss of sight or hearing. In fact, skeptical historians attribute some of the religious visions of the Middle Ages to the visual effects of migraine aura, according to Cameron.
Snacking on high fiber foods between three light meals each day helps stabilize blood sugar and prevent migraines. And while some doctors summarily attribute migraines to diet, other experts attribute at least half of all migraines to food sensitivities. The most common edible villains are aged cheeses, yeast breads, chocolate, cured meats, citrus fruits, eggs, fermented foods, wheat, milk, milk products, alcoholic drinks and food additives, including nitrates and MSG.
Suggested daily supplements for migraine-susceptible individuals include a multivitamin, one capsule of B complex to help maintain normal vascular control, 3,000 to 6,000 milligrams in divided doses of vitamin C with bioflavonoids to assist the production of anti-stress hormones, and 500 to 1,000 milligrams of magnesium to reduce nerve excitability and pain. At the onset of a migraine, says Cameron, try homeopathic remedies, dilutions of natural substances from plants, minerals and animals. For throbbing pain, take natrum muriaticum according to package directions. Other homeopathic options to explore include iris versicolar, lac defloratum and sanguinaria.
Take Charge of Your Headaches
Headache management involves managing your life. Practice relaxation techniques to reduce stress. Calmly discuss your feelings. Take a leisurely stroll at lunch. Walk your dog, or a neighbor's dog, after dinner. Keep a food diary. Sit and stand tall. Skip the fast food tonight. Join a yoga class. Take vitamins and supplements. Get a two-hour massage. Turn the television off earlier and sleep in a little later.
Taking the time to care may take effort, but it will soon become second nature. Invest in yourself. It's your most precious possession.
Ocean Treasures - For centuries, people have flocked to the sea....
June 13, 2005 10:11 AM
Ocean Treasures by Chrystle Fiedler Energy Times, January 3, 2004
For centuries, people have flocked to the sea to take advantage of its healing and restorative powers.
"The ocean is alive with energy and abundant sea life," says Susie Galvez, owner of Face Works Day Spa in Richmond, Virginia and author of Hello Beautiful (MQ Publications). "It's an abundant source. Sea products are rich in minerals like magnesium, potassium, iron and zinc, all of which are known for their deeply cleansing and antibiotic properties. When we think of the sea, we think of health, invigoration, the feeling of being alive and yet peacefully calm."
"To the ancient Greeks, the image of Aphrodite rising out of the sea was beautiful because of the nutrients that the sea plants had given her," says Linda Page, ND, in Healthy Healing (Healthy Healing Publications). Today, sea plants still provide beauty benefits. "They have a complete spectrum of chelated minerals, which makes them easier to absorb, that add lustre and shine to your hair and eyes and improve skin texture and tone."
Thalassotherapy (seawater treatment) includes using salts, mud, foliage, sand and water from the sea to stimulate, hydrate and nourish the skin, making it smoother, firmer and more resilient.
"Using sea products in treatments is both restorative and detoxifying," says Galvez. "Now with modern technology, you don't have to live anywhere near the sea to take advantage of the wonderful health and wellness benefits. Your sea retreat source can be as close as your health food store."
Seaweed's Beauty Benefits
"Pollution, stress, fatigue and bad eating habits all affect the body," says Anne Mok, LaC, a certified Chinese herbalist and co-owner of Cornerstone Healing in Brooklyn, New York. This leads to vitamin and mineral deficiencies that can result in broken capillaries, loss of firmness, skin lesions, dry scaliness and more.
The good news, Mok says, is since seaweed is packed with easy-to-absorb proteins, vitamins, minerals and lipids, it can protect against environmental pollution and ward off aging by nourishing and moisturizing the skin. "The seawater in seaweed is similar to human plasma, so it's an ideal way to get the nutritive benefits from the sea, vitamins A, C and E, and the minerals zinc, selenium and magnesium we need through the process of osmosis. Seaweed cleanses, tones and soothes the skin and regenerates body tissues, offering a new vitality and helping to maintain a youthful appearance. It also improves circulation, which has a positive effect on local fatty overloads and helps maintain the tone of the tissue." No wonder seaweed is used to firm the skin and reduce the appearance of cellulite!
Seaweed captures all the richness from the sea. "There is no genetic manipulation, fertilizer or pesticides, just the sea, light and the tides," says Mok. "[S]eaweed is ten times richer in trace elements than land plants."
Beauty aids from the sea include:
* Kelp (laminaria), a large leafy brown algae, grows along cold climate coastlines and can bring a healthy glow to skin. "Kelp powder has exfoliating properties that make it a great addition to a facial mask," Galvez adds. "It increases blood circulation and stimulates lymph production to eliminate toxins. It's also a mineral-rich body scrub for removing surface impurities."
* Crushed algae is often used in seaweed masks.
* Carrageenan, a gel extracted from Irish sea moss, is commonly used as a cosmetic thickening agent. "It's a great moisturizer that holds nutrients and water in," says Mok.
* Bladderwrack (fucus), a brown seaweed, is often used in cellulite-reducing creams to eliminate excess fluid from the skin.
A Seaweed Beauty Routine
Incorporating the benefits of seaweed into your beauty routine is easy. You can "purchase dehydrated seaweed at a natural food store to make your bath a mini-ocean," says Janice Cox, author of Natural Beauty at Home (Henry Holt & Co). "Fill the tub to the point that you're covered when you lie down," says Dr. Page. "The idea is to make your body sweat, to open your pores, release toxins and take in the sea nutrient benefits by osmosis. Boost the effect with a few drops of aromatherapy bath oils like rosemary and lavender. It'll help hold the heat in and improve your cleansing program." Rinse off and "you'll feel your skin tighten, due to the high iodine content of the seaweed," says Cox. "Your skin should also feel softer and firmer."
Seaweed and algae body wraps are ideal ways to beautify the skin, rid your body of toxins and boost well-being and health. "It starts a program of detoxification very rapidly," says Dr. Page, who has also written Detoxification: All You Need to Know (Healthy Healing Publications). "It's amazing how it encourages weight loss and cellulite reduction." "Seaweed wraps are the most effective cellulite treatments," says Mok. "Seaweed and seaweed mud, especially, stimulate the cells to improve cellular activity and increase the efficiency of lymphatic fluid, which helps break down toxic deposits that can result in cellulite.
"It's excellent conditioning for the skin and leaves it soft and glowing," says Claudia Spagnolo, spa director for the DeFranco Spagnolo Salon and Day Spa in Great Neck, New York.
Revitalize With Sea Salts
Sea salts contain minerals-such as calcium, potassium, magnesium, sodium, iron, sulphur, phosphorus and chlorine-that have a delightfully rejuvenating and revitalizing effect on skin.
"Sea salts enhance the youthful healthy glow of the skin," says Spagnolo. "It creates a deep pore cleansing from shoulder to toe, removing rough, dry skin, helping to purify and slough off dead skin cells. It's great for an all-over exfoliation, and leaves the skin smooth and refreshed."
"Sea salt has wonderful drawing properties, promoting the removal of toxins from the skin," says Galvez, author of Ooh La La Effortless Beauty (MQ Publications). "It's high in mineral content and nourishes the body."
Sea salt also "guards against moisture loss, so it's ideal for dry skin and helps prevent aging," says Mok. In addition, it can be used to treat acne, eczema and psoriasis. Often done before a massage in spas, a "salt glow," which uses a vigorous scrub of coarse sea salts mixed with essential oils, rejuvenates and revitalizes the skin. Sea salt is also readily available at health food stores so you can do the same at home.
Mineral-rich Dead Sea salts pack a salinity of 32%. "When bathing with Dead Sea salt you don't even need to use soap because the minerals remove redundant fat and dirt," says Mok. Dead Sea minerals are often used in shampoos, conditioners and shower gels. "Galvez adds, "Dead Sea mud mineral and vitamin content is very close to that of humans, and therefore treatments using the mud penetrate deeply."
Ah! Home Spa
It's easy to turn your bathroom into an oasis of calm and create a private spa to call your own.
For a sea cure bath, mix together half a pound of sea salt and a pound of baking soda, add to a warm water bath and soak until the water has cooled, says Mok. "It's excellent for soothing itchy and dry skin and helps detoxify by pulling out toxic waste from the pores." Aromatherapy oils, like lavender, make your soak in the tub even more relaxing and luxurious. "It's a great way to de-stress after a long day at work."
A seaweed wrap can release water retention and leave legs looking their sleekest, notes Mok. "Just soak legs in a bath of warm water and Epsom salts for 5 minutes, then pat dry. Apply a seaweed mask and wrap legs with plastic wrap and a warm towel. Relax for 15 minutes. Remove towel and plastic wrap and rinse."
You can also try a sea salt rub by mixing two cups of kosher salt with one cup of olive oil until it forms a thick paste. (Be careful: the oil is slippery.) "While in the tub or shower, massage it into your skin using long strokes toward the heart, starting with your feet," says Galvez. Rinse off with warm water, use a soft washcloth to remove any residue, pat dry and apply moisturizer. "Your skin will be silky smooth and wonderfully hydrated." To create a spa environment at home, details make all the difference. "Think of your favorite Beach get-a-way and go with an ocean theme," says Cox. "Include something for each of the senses." For example, put on a CD that has nature sounds. To capture the color of the water, use sea-colored towels. For scent, light candles that produce the scents of flowering plants (such as plumeria or citrus). Add "ocean" fragrance beads. When taking a bath, "use shells to scoop out sea salts or dehydrated sea weed and put them around the tub as decoration," says Cox. Smooth on a moisturizer with a sea-scented lotion when you finish your spa treatment.
When you make an at-home sea spa experience a regular part of your routine, you reap a bounty of beauty and health benefits. "In just 20 minutes you can have a mini-vacation," says Galvez. "It's cleansing and relaxing."
Then you will be ready to dive back into reality with renewed zest.
Garlic for the Ages - eat garlic because it's good for your heart...
June 13, 2005 09:58 AM
Garlic for the Ages by Phyllis D. Light, RH Energy Times, January 1 , 2004
If you eat garlic because it's good for your heart, you swallow a plant renowned through human history: Garlic was eaten by Roman soldiers for courage; Egyptian slaves ate it to build strength; Christians, Moslems and Hindus include it in their sacred books. Others have used it as an aphrodisiac, a vampire deterrent and a magical charm.
Garlic has a long history as a culinary and medicinal herb that people either love or hate. Its pungent aroma and warming flavor captivates or repels, but its wealth of natural chemicals does great things for your heart.
Garlic (Allium sativum), a member of the onion family, is native to Siberia but, in modern times, has become a treasured naturalized citizen grown all over the world. Garlic's use in folk medicine dates back about 7,000 years, making it one of the oldest known medicinal foods or herbs.
In modern times, garlic is generally used as a condiment lending a unique, pungent flavor to dishes, but in medieval times, garlic was cooked and eaten as a vegetable in its own right. Today you can revel in a wealth of garlic choices, consuming garlic raw, cooked in various recipes, as a dried concentrated powder, as a fresh liquid extract or as aged garlic powder.
Each little clove of garlic is a powerhouse of good-for-you natural compounds, vitamins and minerals. The biologically active constituents of garlic include allyl sulfur compounds as well as the minerals germanium and selenium.
When you chop up raw garlic and allowed it to stand for about 10 minutes or more, the herb's fragments release an enzyme that converts its compounds from allyl sulfur to another natural chemical called allicin.
Although some allicin is found in garlic before it is cut apart, the yield multiplies considerably when the garlic clove is chopped or pressed and exposed to water (Garlic Conference, Newport Beach, 11/15/98; Penn State).
Many researchers believe that the more allicin produced, the better the health benefits. (Although this is still being debated among the garlic cognoscenti.)
But garlic's benefits don't end meekly on the kitchen counter with its allicin content rising.
Cooked garlic and aged garlic contain other helpful chemicals called diallyl sulphides. Consequently, in any form, garlic produces beneficial health effects.
Fortunately, since raw garlic juice or oil can often irritate the stomach lining, especially in people with sensitive stomachs and delicate digestive systems, garlic supplements and cooked garlic are both helpful for heart health.
Aged Garlic Extract
Aging garlic significantly reduces its irritating compounds and makes it easier on the stomach.
In the aged form, all of garlic's healthy sulfur-containing compounds are converted to water- soluble compounds that retain garlic's natural health benefits. In addition, the pungent odor of the garlic is greatly reduced, an outcome many people desire.
When a group of researchers at Brown University studied the effects of aged garlic extract on people's cholesterol levels, they found that after six months, cholesterol dropped about 6% (Am J Clin Nutr 1996; 64:866-70).
In another study from Brown, researchers found that aged garlic extract reduced platelet adhesion, a sticky blood problem that can cause vessel blockages (New Drug Clin 45(3):456-66). When platelets are less sticky, they are less likely to form blood clots that can cause heart attacks.
Garlic and Heart Disease
A growing body of research shows that a clove of garlic a day can significantly reduce your risk of heart disease.
A four-year study of 280 people who took dried garlic powder three times a day found a striking reduction in the types of arterial plaque blockages that threaten the blood supply to your heart. Interestingly, in this particular study, women displayed a greater reduction in plaque than men (Atherosclerosis 2000; 150:437-8).
Another study found that garlic may also keep important blood vessels more supple and less likely to spasm. Arterial spasms have been linked to heart attacks and other cardiovascular problems in women.
As you age, the aorta, one of the main arteries that carries blood, may harden, reducing blood flow from the heart and placing damaging stress on a number of other bodily organs. In research at Ohio State University, people who took garlic supplements had 15% less aortic stiffness than people who avoided garlic (Circulation).
In this study, scientists found that the older people enjoyed the greatest cardiovascular benefits from daily garlic use.
Researchers believe this extra benefit is linked to the fact that as you age, the endothelial tissue in the linings of the aorta and other blood vessels become less responsive to the need to dilate (expand). As a result, when more blood flow is required, and the heart pumps faster, these vessels take more of a beating from the friction of blood passing through them.
That restriction in dilation has two damaging consequences: In one instance, vessel walls can be injured. In response to these injuries, cholesterol collects on artery walls, plaque forms and the blood supply to the heart muscle can be restricted, leading to a heart attack. In other cases, arteries can restrict blood flow to the heart simply because of the inability to expand sufficiently.
The Ohio State researchers found that arteries in folks aged 70 to 80 benefited the most from taking garlic. But those in their 60s also benefited significantly.
Garlic's natural antioxidant properties can also help protect the heart from damage after surgery (BMC Pharmacology 9/02).
In a study performed on lab animals, researchers found that oxidative stress, a source of cell damage that takes place after surgery, dropped when the animals ate a diet that included garlic.
Oxidative stress can seriously reduce cardiac function, limit the amount of blood the heart can pump and cause permanent damage to the heart muscle.
Garlic Against Blood Clots
Under normal circumstances, blood clots serve a useful purpose: Cut yourself and a blood clot stops the bleeding. Without this clotting ability, you might bleed to death. But if your blood is too prone to clotting, these clumps can cut off blood supply to your heart and other organs, endangering your life.
In a study of apparently healthy individuals whose relatives had already suffered from heart disease, researchers found that their blood formed thick, tangled blood clots, increasing their risk of heart problems (Circulation rapid access 9/23/02). These blood clots are made of a substance called fibrin, a protein in the plasma that can form elastic threads that cut off blood flow.
While these researchers recommended aspirin as an anti-clotting measure for people at risk of heart disease, garlic can also help break up fibrin and possibly lower your chance of heart problems (Pharmatherapy 5(2): 83).
The fibrin that forms clots is produced by blood cells called platelets. Other scientists who have looked into garlic's benefits believe that one of its natural chemicals called ajoene may keep platelets from producing excessive fibrin and gumming up the flow of blood through arteries.
If you've rarely indulged in garlic, you may need a period of adjustment in growing accustomed to its unique taste and aroma. But its heart benefits confirm the long-ago observation by Pliny, an ancient Roman naturalist, that "garlic has powerful properties."
Summer Sports Nutrition Guide
June 11, 2005 03:54 PM
Summer Sports Nutrition Guide by Joyce Dewon Energy Times, June 18, 2004
If you're hooked on exercise you're probably just as hooked on using top-notch equipment when you work out. Those who are serious about staying in shape buy the best running shoes, carefully pick out the best bikes and tread on durable treadmills. But do you pay just as much attention to your nutrition?
Scientists who have studied exercise have found that what you eat before, during and after workouts is crucial to maintaining your health, getting into shape and staying fit. To achieve your best athletic performance without getting injured or sick depends on optimum nutrition. When you carefully plan what to feed your exercised body, it rewards you by feeling and looking better.
Short 'n Sweet
If you thought long exercise sessions were the only ways to get decent exercise benefits, take notice: small doses of exercise during the week can go a long way. " The important thing, apparently, is just do it," says Howard D. Sesso, ScD, author of an American Heart Association study on exercise and heart disease. In his study, exercisers demonstrated that several short sessions of exercise were as good for the body as a single long session (Circ 8/00; 102:975-80). " Short sessions lasting 15 minutes long appear to be helpful,"Dr. Sesso explains. Even walking about three miles per week, which is a moderate level of exercise, lowers your risk of heart disease by 10%.
Some people glorify in working up a sweat; others curse the dampness. But putting in extra effort in even short bursts of activity pays off: experts have found that intense exercise burns more calories than more relaxed sessions, more effectively reduces your risk of cardiovascular disease and helps stabilize blood sugar levels. In addition, it stimulates production of human growth hormone, which offsets some of the effects of aging (Exp Biol Med 2004 Mar; 229(3):240-6).
But don't go crazy if you haven't worked out in a long time. The intensity of the workout should match your physical fitness. According to the American Heart Association, when people exercise at a comfortable pace, their heart rate and level of exertion stay within a safe range, but still high enough to benefit their health. Strenuous activities, for those who can handle them, produce the most physiological bang for the jog. But brisk walking within your own level of fitness still offers significant benefits.
Feeding Your Muscles
When you exercise, you work and develop your muscles, which are made primarily out of protein. Despite this fact, many exercise experts have advocated high-carb diets for athletes. But, as John Ivy, PhD, and Robert Portman, PhD, point out in their book The Performance Zone (Basic Health), "[While] there is no doubt that aerobic athletes require more carbohydrate than strength athletes...we are now discovering that the addition of protein to a carbohydrate supplement offers significant benefits to aerobic athletes."
That is why researchers believe that consuming plenty of protein along with carbohydrates offers the best fitness benefits. Protein helps fuel activity more efficiently and aids in recovery after a session at the gym, allowing your body to repair muscle damage and build up muscle fibers.
During exercise, you break down muscle tissue. It is during recovery, after your exercise session ends, that muscles are rebuilt. At the same time, other cellular processes take place that adapt the body to working out.
According to Ivy and Portman, timing your intake of nutrients after exercise is crucial: "The ability of the muscle machinery to regenerate itself decreases very rapidly after a workout, so that the nutrients consumed more than 45 minutes after exercise will have far less impact in helping the muscles regenerate than nutrients consumed earlier."
Stresses and Tears
Engaging in athletics can cause microscopic muscle tears. These tears can cause a range of problems that, when you exercise excessively, can cause pain and injury.
Inflammation is the body's response to cellular damage. The damaged area can swell as the body sends white blood cells and other cells to repair the injured area. Unfortunately, the swelling can further damage the muscle cells.
Since inflammation can take 24 hours or more to cause the collection of cells in the injured area, it can be a day or two before the resulting muscle soreness reaches its peak painfulness and then starts to subside.
Cortisol, a hormone produced when you exercise strenuously, which can result in muscle fiber damage. Cortisol boosts protein breakdown, so it can be used to fuel muscle movement. But the more protein breaks down, the more potential exists for muscle fiber injury. Free radicals are caustic molecules that are created when the mitochondria (small structures in cells) create energy; these marauders can also cause microscopic shredding of muscle strands. As you increase your use of energy during exercise, you simultaneously increase the production of free radicals. This collection of free radicals can outstrip the body's antioxidant defenses, leading to extensive muscle damage and dampening of the immune system.
All of these cellular events can make you sore. They are also the reasons that athletes who overdo it day after day are liable to come down with nagging colds and a variety of infections.
Your muscles use different substances for fuel depending on what you ask them to do. Lift a heavy weight and muscles recruit two processes called the creatine phosphate system and glycolysis to generate a large amount of quick energy. These are known as anaerobic types of energy production.
But if you jog, swim, bike or perform any other aerobic activity, the cells use oxygen in what is called cellular respiration to supply energy to working muscles.
When you exercise aerobically for extended periods of time, the energy available is generally limited by how much oxygen your body is capable of taking in and supplying to the muscles, where it takes part in energy production. In athletic circles, this upper limit is known as your VO2max.
The carbohydrates your body burns for energy during aerobic activity are taken from blood sugar and carbohydrate reserves called glycogen. (The muscles store glycogen, as does the liver.) During a workout session, your glycogen supply is limited to what is stored with your muscles. But blood glucose can be boosted by carbohydrate drinks, energy gels or bars.
Most people who work out have enough glycogen and blood sugar to fuel moderate aerobic activity for about two hours. After that, the body turns mostly to fat and protein stores to fuel exercise.
Fat Into the Fire
In contrast to the body's quickly diminishing supply of glycogen and blood sugar, fat can last for hours and hours of exercise. According to Portman and Ivy, a 200-pound man with 15% body fat has, theoretically, enough fat energy to run from Washington DC down to Miami Beach-and still has enough energy left over to jump into the ocean.
But using fat for energy is complicated; fat is stored in fat tissue and not readily available to working muscles. Plus, to burn fat for energy, the body needs carbohydrate-it cannot burn fat all by itself. What's more, the conversion of fat into energy doesn't go as quickly as carb conversion.
Protein is also used for energy when carbs run low. But the more you use protein for energy, the more you risk soreness as muscle fibers break down.
Prepare to Energize
To maximize your energy during exercise and minimize soreness, Portman and Ivy recommend some simple nutritional steps:
Taking protein and carbs while working out can limit muscle damage and curtail soreness. Carbs apparently drop your cortisol levels, and thereby limit muscle injuries linked to this hormone. While the mechanism that helps protein limit muscle soreness is not completely understood, it is possible that taking in protein while working out keeps the body from shredding muscle tissue in search of fuel.
Supplements that contain antioxidants such as natural vitamin E and vitamin C (Portman and Ivy think you should take these during exercise) may limit free radical damage to muscle fibers.
Muscle Reconstruction Plan
If you want to help your exercise plan make you stronger, you should focus your after-exercise sports nutrition plan on these steps:
The protein part of the equation is vital: don't merely indulge in only carbs after exercising. A recent study found that while carbs could help muscles rebuild, adding protein can make a big difference in improving your fitness (J App Phys 2/04).
This combination of nutrients stimulates the pancreas so that it releases insulin. The release of insulin is the key, initial step that sets off a cascade of physiological events that speeds muscle recovery. Although many people think of insulin as an undesirable hormone-if you never exercise, too much insulin may help drive your blood sugar down and cause other problems-for exercisers, this hormone plays a crucial function in benefiting from exercise.
By eating carbohydrate and protein soon after working out and stimulating insulin, according to Ivy and Portman, you help your body boost its synthesis of protein by:
Drinking for Exercise The most obvious nutrient you lose during intensive exercise is water in your perspiration. However, that perspiration also contains an array of minerals known as electrolytes. So, for optimal performance and health, experts recommend you replace both the water and its minerals.
Merely drinking water-instead of electrolyte-filled sports drinks-during prolonged aerobic activity can be dangerous. It leaves you vulnerable to a condition called hyponatremia, which can occur when your blood levels of sodium and other electrolytes drop, but your blood volume stays steady or increases because you drink lots of water.
According to Edmund Burke, PhD, in his book Optimal Muscle Performance and Recovery (Avery), one out of four athletes who seek medical attention after a long race are suffering hyponatremia.
" Typically," he says, "conscientious athletes get in trouble because they adhere too diligently to one recommendation: the need to drink lots of fluids. They tend to ignore another recommendation: The need to keep electrolytes up...for most endurance athletes the real problem is drinking too much water." Dr. Burke warns that you can possibly suffer hyponatremia even if you don't drink a lot of water.
Signs of hyponatremia can be similar to those of heat exhaustion. But, while resting and cooling down can help alleviate heat exhaustion, that doesn't help hyponatremia. " To protect yourself against hyponatremia, start by paying attention to how much you sweat," Dr. Burke says. If your sweat seems very salty, burns your eyes or leaves an evident, white residue on your skin, you may be losing a great deal of sodium and should be diligent about eating salty foods. " You can also make sure you're getting enough sodium by drinking sports drinks instead of plain water during long (exercise) events," Dr. Burke notes.
Of course, no matter what you decide to eat or drink while exercising, the most important factor for your well-being is to get out to the gym, onto the track, or just on to the sidewalk, and do something, even if you only want to go out for a walk. No matter how old you are or what kind of shape you're in, you'll benefit from exercise.
" It's solid evidence that across-the-board declines occur when people stop exercising," says Charles Emery, PhD, professor of psychology at Ohio State University (Health Psychology 3/04).
Don't decline or remain supine. Let your fitness climb.
Niacin and Cholesterol -- abstracts states blocks cholesterol absorption ...
May 21, 2005 11:20 AM
The Era of Statins - Is There Still a Place for Other Classes of Lipid-Lowering Drugs? Wascher, Thomas C. Department of Internal Medicine, Diabetes and Metabolism Unit, and Diabetic Angiopathy Research Group, Medical University of Graz, Graz, Austria. HeartDrug (2005), 5(1), 34-38. CODEN: HEARCO ISSN: 1422-9528. Journal; General Review written in English. CAN 142:384798 AN 2005:64730 CAPLUS
A review. Plenty of evidence suggests statins as the first-line therapy for the treatment of lipid disorders. However, further therapeutic options available in the treatment of lipid disorders are fibrates, niacin and cholesterol absorption inhibitors. In the present study, current treatment modalities of lipid disorders are reviewed, and their use was scrutinized based on the available evidence.
Niacin and cholesterol: role in cardiovascular disease (review). Ganji, Shobha H.; Kamanna, Vaijinath S.; Kashyap, Moti L. Atherosclerosis Research Center, Department of Veterans Affairs Healthcare System, Long Beach, CA, USA. Journal of Nutritional Biochemistry (2003), 14(6), 298-305. CODEN: JNBIEL ISSN: 0955-2863. Journal; General Review written in English. CAN 139:291534 AN 2003:542279 CAPLUS
A review. Niacin has been widely used as a pharmacol. agent to regulate abnormalities in blood plasma lipid and lipoprotein metab. and in the treatment of atherosclerotic cardiovascular disease. Although the use of niacin in the treatment of dyslipidemia has been reported as early as 1955, only recent studies have examd. the cellular and mol. mechanism of action of niacin on lipid and lipoprotein metab. The beneficial effects of niacin in decreasing triglyceride and apolipoprotein-B contg. lipoprotein (VLDL and LDL) levels are mainly due to decreased fatty acid mobilization from adipose tissue triglyceride stores and inhibition of hepatocyte diacylglycerol acyltransferase and triglyceride synthesis, leading to increased intracellular apolipoprotein-B degrdn. and subsequent decreased secretion of VLDL and LDL particles. The mechanism of action of niacin to raise HDL levels involves decreasing the fractional catabolic rate of HDL-apolipoprotein A-I without affecting its biosynthetic rates. Niacin selectively increases blood plasma levels of Lp-AI (HDL subfraction without apolipoprotein A-II), a cardioprotective subfraction of HDL in patients with low HDL levels. Using human hepatocytes (Hep G2 cells) as an in vitro model, recent studies indicate that niacin selectively inhibits the uptake/removal of HDL-apolipoprotein A-I (but not HDL-cholesterol ester) by hepatocytes, thereby increasing the capacity of retained HDL-apolipoprotein A-I to augment cholesterol efflux through reverse cholesterol transport pathway. The data provide evidence extending the role of niacin as a lipid-lowering drug beyond its dietary role as a vitamin.