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	Did you know that glutathione is not only great for liver health, but it also promotes beautiful, radiant skin?	Darrell Miller	12/7/23
	The Coconut & Thyroid Connection: How This Tropical Nut Supports Healthy Thyroid Function	Darrell Miller	5/24/17
	6 Things I Learned About Ulcers	Darrell Miller	4/19/17
	Wonders Of Elderberry	Darrell Miller	10/25/13
	How Can I Raise Blood Pressure Naturally?	Darrell Miller	10/18/11
	Revita	Darrell Miller	3/8/07
	Q. Why not just take IP-6 by itself? Why does IP-6 need to be combined with inositol?	Darrell Miller	11/22/06
	Cancer, The Immune System, and Nutritional Supplements	Darrell Miller	11/22/06
	Educator in Glyconutrient Technology and Cellular Restoration	Darrell Miller	9/19/06
	Product Resurfaces under a new name - from HSI - Health Sciences Institute	Darrell Miller	7/8/06
	GliSODin Anti-Aging and Antioxidant Protection	Darrell Miller	12/19/05
	Why does IP-6 need to be combined with inositol?	Darrell Miller	11/11/05
	Omega Man - For Men Interested in Optimal Health	Darrell Miller	8/12/05
	STEVIA (Stevia rebaudiana)	Darrell Miller	7/15/05
	Your Healthy Harvest	Darrell Miller	6/14/05
	Energy Cycles - Stress and lack of energy don't just frazzle your nerves	Darrell Miller	6/12/05
	Herbs in Perspective	Darrell Miller	6/10/05
	COENZYME Q10 - Transforming food into energy	Darrell Miller	6/1/05
	Nattokinase: Food For Cardiovascular Health	Darrell Miller	5/10/05

Date: December 07, 2023 12:12 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Did you know that glutathione is not only great for liver health, but it also promotes beautiful, radiant skin?

Did you know that glutathione is not only great for liver health, but it also promotes beautiful, radiant skin?

Glutathione (GSH), often considered as an amino acid but actually a tripeptide, is an antioxidant primarily synthesized in the liver. Composed of cysteine, glutamic acid, and glycine, it plays a crucial role in the synthesis and repair of DNA and protein, as well as the synthesis of prostaglandins. With its involvement in various functions like amino acid transport, toxin and carcinogen metabolism, immune system function, prevention of oxidative cell damage, and activation of enzymes, it is undoubtedly the most important tripeptide in the body.

While the benefits of supplementing with glutathione are numerous, two particularly compelling reasons are its positive impact on liver health and beautiful skin, which are the key focus of this article. However, before diving into the specifics of liver health and skin benefits, it's important to review the data on glutathione depletion and absorption.

GSH depletion can occur due to various oxidative stressors such as radiation, v.infections, enviro toxins, household chemicals, heavy metals, surgery, inflammation, burns, septic shock, and dietary deficiencies of GSH precursors and enzyme cofactors. Additionally, research suggests that GSH levels tend to decline with age.

The bioavailability of glutathione as a dietary supplement has encountered challenges in the past. Studies in the 1990s suggested that oral GSH might be inactivated by peptidases in the gut, as the levels of glutathione in the body did not seem to correlate with dietary intake, despite its presence in fruits, vegetables, and meats. Moreover, previous studies showed no significant increase in blood GSH levels when subjects were given high doses of 1,000-3,000 mg. As a result, alternative strategies like supplementation with NAC were used to boost GSH levels.

In 2014, something interesting Happened that changed the way we look at the bioavailability of GSH. A groundbreaking study published in the Journal of Agricultural and Food Chemistry shed new light on the old research. This study showed that GSH, when taken in its intact form as OPITAC, a yeast-derived glutathione by Kohjin/Mitsubishi, can actually be rapidly transported across intestinal epithelial cells. Once inside, it gets rapidly converted into oxidized glutathione (GSSG) and accumulates in red blood cells and the liver, with only a small presence in plasma. So, although the GSH was indeed absorbed, it didn't show up in blood plasma because it transformed into GSSG and stored in the red blood cells and the liver. The bottom line is, supplementing with GSH is an effective way to boost GSH levels in the body.

This finding was further confirmed in another study that described how OPITAC, as a yeast-derived glutathione by Kohjin/Mitsubishi, is directly absorbed in its electrochemically reduced form in the intestine, then transported in the blood in bound forms, and eventually deposited into the liver in its reduced form.

But here's where it gets even more significant. A six-month randomized, double-blinded, placebo-controlled trial involving 54 adults was conducted to investigate the effects of oral GSH supplementation (250 or 1,000 mg/day, as OPITAC glutathione, Kohjin/Mitsubishi) on GSH levels in various parts of the body, including blood, erythrocytes, plasma, lymphocytes, and exfoliated buccal mucosal cells. The results were astounding. After one, three, and six months, GSH levels in blood increased significantly compared to baseline in both dosage groups. At the six-month mark, GSH levels skyrocketed 30-35 percent in erythrocytes, plasma, and lymphocytes, and a mind-boggling 260 percent in buccal cells in the 1,000 mg group (P < 0.05). Even in the low-dose group, GSH levels in blood and erythrocytes increased by 17 and 29 percent, respectively (P < 0.05). This research clearly demonstrates that supplementation with GSH is not only effective for increasing GSH levels in the body but also for maintaining them.

So, to sum it all up, the evidence speaks volumes - supplementing with GSH can have a profound impact on your body's GSH levels, and trust me, that's definitely a good thing!

Liver Health

When it comes to our well-being, the liver is a true superhero. Let's dive into some fascinating details about this essential organ.

Did you know that the liver is not only the largest reservoir of GSH (glutathione) but also a major site of GSH manufacture in the body? Pretty impressive, right? Special cells in the liver work tirelessly to synthesize GSH, which plays a crucial role in detoxification. Speaking of detoxification, the liver is a champion in this field. Its cells have sophisticated mechanisms to break down toxic substances, be it internal or external compounds.

During the detoxification process, the liver attaches or conjugates the toxins to water-soluble substances. This attachment makes the toxic molecules more water-soluble, less harmful, and easier to eliminate via urine or bile. In fact, glutathione conjugation produces water-soluble mercaptates that are excreted via the kidneys, effectively detoxifying acetaminophen and nicotine. Isn't it amazing how this process helps our bodies get rid of harmful substances?

But that's not all. Adequate levels of glutathione are crucial for the elimination of fat-soluble compounds, particularly heavy metals like mercury and lead. What's more, GSH serves as a cofactor for various peroxidase enzymes, aiding in the detoxification of peroxides generated from oxygen radical attacks on biological molecules. It also assists transhydrogenase enzymes in reducing oxidized centers on DNA, proteins, and other biomolecules. Talk about a multitasker!

The practical significance of this liver superhero was demonstrated in a study involving workers exposed to lead. A group of five workers received GSH at 200 mg/day for 30 days, while five others served as the control group. The results were striking. The group receiving GSH showed a significant increase in ALA dehydratase activity (which is inhibited by lead) compared to the control group (p < 0.05). This indicates that GSH could be a valuable solution for treating patients with lead poisoning.

So, let's take a moment to appreciate the remarkable liver and its incredible role in maintaining our health and well-being!

Alcohol Intoxication

Alcohol consumption is widely recognized for its capability to induce hepatic steatosis, also known as fatty liver disease, and disrupt biomembranes due to hepatic lipid peroxidation. This can lead to various lifestyle-related diseases and even hepatic cirrhosis by diminishing hepatic physiological function. Nevertheless, animal studies have shown that hepatic damage caused by alcohol intoxication can be mitigated by glutathione (GSH), a powerful antioxidant found in cells.

To further investigate the impact of GSH supplementation on the effects of alcohol intake, a human crossover comparative study was conducted. The study involved twenty healthy men and women who were grouped into three categories: placebo, 100 mg GSH (as OPITAC glutathione, Kohjin/Mitsubishi), and 30 mg curcumin. The study evaluated laboratory parameters, including breath alcohol concentration at different time intervals (20, 60, 120, and 180 minutes post-alcohol consumption) as measured by an alcohol checker. Additionally, subjective feelings were assessed through a questionnaire. During the study, all participants consumed whiskey in a quantity equal to their body weight multiplied by 1.25 mL, and were instructed to drink the entire sample within 10 minutes.

The results revealed that the breath alcohol concentration in the group supplemented with GSH significantly decreased compared to the placebo and curcumin groups at 20 (p<0.01), 60 (p<0.01), 120 (p<0.05), and 180 (p<0.08) minutes post-consumption. Furthermore, the GSH group reported lower levels of "sleepiness," "headache," and "upset stomach" in the subjective feeling questionnaire. Importantly, the concentration of aspartate aminotransferase (AST), an indicator of alcohol-induced organ damage, was significantly lower in the GSH group after two months compared to the placebo group.

The oral intake of GSH has demonstrated its effectiveness in reducing alcohol consumption-related stress and improving long-term hepatic function. These findings highlight the potential benefits of GSH supplementation in alleviating the detrimental effects of alcohol intoxication on the liver.

Nonalcoholic fatty liver disease

Nonalcoholic fatty liver disease (NAFLD) is a condition characterized by the build-up of fat in the liver of individuals who consume little or no alcohol. Unfortunately, NAFLD is quite common, affecting nearly one-third of all American adults. Interestingly, it often presents without readily apparent signs or symptoms, sometimes resulting in complications, and can lead to liver inflammation and scarring as the fat accumulates. Additionally, NAFLD is typically associated with conditions such as insulin resistance, central obesity, reduced glucose tolerance, type-2 diabetes, and elevated triglyceride levels.

Recognizing the substantial role glutathione (GSH) plays in phase 2 liver detoxification, a pilot trial was conducted to examine the therapeutic effects of GSH supplementation in patients with NAFLD. The trial included 29 individuals, and the patients were provided with daily oral supplementation of GSH at a dose of 300 mg (in the form of OPITAC glutathione, from Kohjin/Mitsubishi). The patients' clinical parameters were assessed before and after the GSH supplementation, and liver fat and fibrosis were quantified as well. The primary goal of the study was to determine any changes in alanine aminotransferase (ALT) levels. The results indicated a significant decrease in ALT levels following the GSH supplementation. Furthermore, triglycerides, non-esterified fatty acids, and ferritin levels also showed a reduction. This pilot study provides promising evidence for the potential therapeutic effects of oral glutathione administration, even at practical doses, in patients diagnosed with NAFLD. However, further investigation through large-scale clinical trials is necessary to validate its efficacy.

In summary, NAFLD is a prevalent condition with potential serious consequences, but studies like the aforementioned pilot trial shed light on potential treatment options such as GSH supplementation. The findings demonstrate the need for continued research in order to provide more conclusive evidence and expand our understanding of NAFLD management.

Beautiful Skin

By activating melanocytes in the skin, there is a notable increase in melanin formation, resulting in various blemishes such as freckles, pigmentation, and UV-induced skin spots, commonly known as age spots or liver spots. This is especially prominent after prolonged sun exposure and tanning. Age spots appear when melanin becomes concentrated or "clumped" in areas that have had years of frequent sun exposure. Luckily, there are materials like glutathione that can prevent or improve such pigmentation-related skin conditions.

Another aspect to consider is skin pigmentation, wrinkles, and pores. In a study conducted with eight women in their 30s or early 40s, each supplemented with 100 mg/day of GSH (as OPITAC glutathione, Kohjin/Mitsubishi) for two months, their skin conditions were evaluated using the Robo Skin Analyzer. Several parameters were analyzed, including skin brightness, the amount and area of skin pigmentation, number of pores, and number of wrinkles under the eyes. It was observed that all subjects' skin brightness improved when measured on the second day of the study. Additionally, over the course of the two months, both the amount and area of skin pigmentation decreased, leading to an improvement in blemishes and pigmentation. Not only did glutathione exhibit a whitening effect, but it also reduced the number of wrinkles under the eyes and minimized pores.

Furthermore, a randomized, double-blind, two-arm, placebo-controlled study was conducted with 60 otherwise healthy medical students. The purpose was to investigate whether supplementing with 500 mg of glutathione daily for four weeks would affect the skin melanin index compared to a placebo. Melanin indices were measured at six different sites on the body. The results demonstrated that melanin indices consistently decreased at all six sites in subjects who received glutathione after four weeks. The reductions were statistically significant compared to those who received the placebo at two sites: the right side of the face and the sun-exposed left forearm (p = 0.021 and 0.036, respectively). This improvement was likewise reflected in the reduction of UV spots. Importantly, both glutathione and placebo were well-tolerated. In conclusion, oral administration of glutathione leads to a lightening of skin color in the tested subjects.

Skin Lightening

Skin lightening is a process that is of interest to many individuals who seek to achieve a more even and radiant complexion. In recent studies, the use of a lozenge containing GSH 500 mg was explored as a means of skin lightening through an open-label, single-arm trial. The focus of this trial was to evaluate the buccal mucosa as a route for GSH administration and its potential in relation to skin lightening. It is worth noting that substances absorbed through the buccal route have the advantage of entering directly into the systemic circulation, effectively bypassing the gastrointestinal tract.

The trial involved thirty Filipino females with Fitzpatrick skin types IV or V who received a daily glutathione-containing lozenge for eight weeks. The results from this trial demonstrated a significant decrease in melanin indices from baseline to endpoint. What is fascinating is that this visible change became evident in as little as two weeks. It is important to highlight that during this trial, there were no recorded serious adverse events, and the laboratory examination findings remained normal. Based on these findings, the researchers concluded that the lozenge containing glutathione was deemed safe and effective in lightening the skin of Filipino women.

In addition to the aforementioned buccal route administration, another interesting approach that emerged from the studies is the topical application of GSH. A double-blind randomized clinical trial35 conducted in Yogyakarta, Indonesia, involved 74 healthy Indonesian women, with an average age of 33.3 ± 5.9 years, to explore the potential benefits of topical GSH. The trial subjects received supervised applications of facial wash twice a day, along with day cream containing sunscreen and night cream. The subjects were divided into three groups based on the active ingredients of the tested products, which included GSH (as OPITAC glutathione, Kohjin/Mitsubishi) at concentrations of 0.1 percent and 0.5 percent, and a control group without GSH.

Throughout the trial, the effects of the tested products on skin color and pigmentation were measured using colorimetry with Chromameter Minolta for L. Compared to the baseline measurements, there were significant increases in lightness (L) detected as early as week 2 for the group using GSH at 0.1 percent concentration. Interestingly, this increase was significantly higher compared to the group using GSH at the higher concentration of 0.5 percent, as well as the group without GSH. It is important to note that hyperpigmented lesions also showed improvement, particularly in the group using GSH at 0.5 percent concentration, which displayed superiority compared to the other groups at week 8. In conclusion, the skin care products containing GSH at 0.1 percent and 0.5 percent concentrations were found to be effective in lightening facial skin.

The findings from these studies shed light on the potential benefits of GSH in achieving skin lightening, either through buccal administration or topical application. It is worth noting that these studies focused on specific populations and more research is necessary to explore its effectiveness and safety across different skin types and ethnicities.

In summary, the administration of glutathione, whether oral, buccal, or topical, has shown promising results in skin lightening and the improvement of complexion. Studies have demonstrated that glutathione not only enhances skin brightness but also reduces hyperpigmentation, wrinkles, and minimizes pores. Moreover, its effects have been evident in as little as two weeks, with a sustained impact over longer periods. These benefits were observed across a range of different skin types and ethnicities. However, it is important to highlight that these findings are based on specific populations, and more research needs to be conducted to confirm the consistency of these effects across a broader spectrum of skin types and ethnicities. The studies have also confirmed that the usage of glutathione is well-tolerated with no serious adverse effects reported.

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Date: May 24, 2017 08:44 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: The Coconut & Thyroid Connection: How This Tropical Nut Supports Healthy Thyroid Function

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Date: April 19, 2017 03:44 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: 6 Things I Learned About Ulcers

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Date: October 25, 2013 07:56 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Wonders Of Elderberry

 Elderberry

The bushy like appearance, which characterizes this elderberry tree is what makes it noticeable in and around Britain. Its name means fire, which is because of a certain goddess Happened to consider this tree sacred and after she passed on, it was believed that her soul continued to reside in the tree.

Common infections in women such as yeast are also catered for when it comes to the Elder tree as it constitutes the required substances that are responsible for taking care of the yeast infections.

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Date: October 18, 2011 05:25 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How Can I Raise Blood Pressure Naturally?

Overview

One of the leading causes linked to most illnesses in some form or the other is an imbalanced blood pressure. Statistics have shown that 1 out of 3 adults in the US have imbalanced blood pressure. So much of our bodily functions rely on normal blood pressure to work well. Let us put it this way, if your blood pressure is higher than it is supposed to be that means it is giving your body more workload than it is supposed to have, so in turn what will Happened is, your body’s degeneration will be amplified. A lot of your systems will be overworked, your heart will be overworked and eventually depending on the cause your arteries will take a beating causing other organ failures in more severe cases. Now on the other hand if blood pressure is too low, you may feel fatigued all the time, light headedness, dizziness, nausea, close to fainting or anxiety and these are all things that we want to avoid.

Blood Pressure

This is the process in which the blood is carried from the heart towards other parts of your body. This is done through blood vessels called arteries and ultimately blood pressure is defined as the force of the blood in which it pushes the arterial walls. How much pressure is experienced is also directly proportional to how much the heart beats per minute in other words blood pressure is also directly proportional to the rate of your heart beat. The faster it beats the higher your blood pressure is. The blood pressure form of measurement is based on systolic over diastolic rates. Simply put the systolic rate is when the heart pumps blood and the diastolic is when the heart is at rest in between pumps or beats and that is why the diastolic is usually lower than the systolic rate. With that said by now you probably are able to make the conclusion that blood pressure will be at its highest when you are active, nervous, or excited and on the other hand it is at its lowest when you’re a sleep.

Why would you want to increase your blood pressure?

Most of us will probably think that, that idea is ludicrous since most of us would like to avoid high blood pressure and a lot of us are taking medications to support that effort and do things like exercising and all the other stuff to help fight against high blood pressure. However there is also a problem when blood pressure is too low as stated above and that is why some people need to increase blood pressure. There are a couple of ways to do it. First and foremost is for you to make sure you are hydrated well. High liquid volume in the body will promote higher blood pressure. Second is to lie down and elevate your feet. This will increase the return of blood to the heart therefore increasing blood pressure. Eat smaller meals so that the body will not divert so much blood to your digestive tract for digestion. Some studies also have shown that small amounts of caffeine daily may help increase low blood pressure.

You can also try herbs like bitter melon and yohimbe to elevate the heart rate. An elevated heart rate will effectively raise blood pressure. If you have low blood pressure or high, make sure you get tested every other day and record the results. Maintaining a BP level of 80/120 is optimal for good health.

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Date: March 08, 2007 12:27 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Revita

Revita, the most efficient hair growth stimulating shampoo available in the market is the final result of DS Laboratories efforts on cutting edge research. Revita is a powerful and unique SLS/SLES free combination of active ingredients specially designed to maintain scalp vitality and act on folicle dysfunctions in order to achieve best results in short periods of time. Sodium Lauryl Sulfate and Sodium Laureth Sulfate, commonly used low cost detergents in shampoos and cleansers, are linked to skin irritation, skin drying and hair loss due to follicle attack. Revita is Sodium Lauryl Sulfate and Sodium Laureth Sulfate free, providing a high quality scalp skin safe shampoo product.

Revita was developed with a cost-no-object approach. Revita’s compounds have been chosen based exclusively on their properties, quality and efficacy (in the opposite of the majority of available products, which are usually developed with production costs in mind). The final result is a very high quality shampoo product with absolutely no equivalent competitor in the market. Revita combines costly first line compounds at high concentrations like Caffeine at 4.0%, Pyrus Malus (Apple) Seed Extract at 1.0% and Spin Traps (SOD Mimic) at 0.1% with other top level ingredients which make Revita a unique product in its class.

To improve the efficacy of this synergic combination, DS Laboratories developed a unique “chemical free” extraction process that keeps original properties and clinical efficacy of final components. Through gentle mechanical compression, Revita’s compounds are obtained as pure and chemically preserved active molecules.

Revita starts acting on your scalp and hair follicle since the first day of use. The time you will need to note the first results will depend of the severity and duration of your hair loss. No matter how long or how intense your hair loss is, using Revita on daily basis will improve the vitality of your scalp, maintaining the quality of your hair and stimulating new hair growth.

Through the synergic interaction of very effective compounds, Revita brings you a highly effective product designed to maintain scalp vitality and act on hair loss. By combining an antioxidant effect, anti-DHT properties, powerful hydrating molecules, hair growth stimulants and structural amino acids, Revita brings you the most effective hair growth stimulating shampoo available.

Apple Polyphenol (procyanidin B2 and C1) - phytochemical concentrate found in the skin of unripe apples that acts as potent antioxidant. It protects cells against free radicals, reactive atoms that contribute to tissue damage in the body. These chemical compounds are being studied extensively in labs around the world for their health effects in major diseases including treatment of hair growth. Studies showed that after sequential use, an increase of almost 80% of hair diameter and an increase in number of total hairs was shown, with no side effects.

In 2000, Japanese researchers presented their findings to the international community on the hair growth effects of apple polyphenols - specifically one known as procyanidin B-2. They identified two successful compounds- one from chardonnay grapes, and one extracted from unripe apples. The procyanidin B-2 fraction clearly outperformed the grape extract. "Procyanidin B-2 purified from apples," stated the research team, "shows the highest activity of more than 300% relative to controls."

In the same year, in a double-blind placebo-controlled trial, nineteen men with male pattern baldness were studied with a daily topical application of a 1% procyanidin B-2 solution, extracted from apples. Ten other balding men served as controls, receiving a placebo solution. After 6 months, the study concluded:

• The increase in number of total hairs and terminal hairs in the procyanidin B-2 group subjects was significantly greater than controls.

• 78.9% of subjects showed an increased mean value of hair diameter.

• "Procyanidin B-2 therapy shows promise as a cure for male pattern baldness."

Following the revelations, an attempt was made to further understand the mechanism by which the remarkable hair growth effects occurred. The results were published in the prestigious British Journal of Dermatology: Procyanidin B-2, extracted from apples, promotes hair growth: a laboratory study, Br J Dermatol. 2002 Jan;146(1):41-51. In this study, the researchers concluded that procyanidin B-2 acts to diminish protein kinase C isozymes, which play an important role in the hair growth cycle. Procyanidin B-2 seems to promote hair growth by down regulating PKC in both the anagen (active growth phase) and telogen (resting phase) of the hair follicle. When the anagen phase is prolonged, and the telogen phase is shortened, increased hair growth results.

Two more clinical trials and a total of seven published studies have now confirmed the surprising hair growth-promoting effects of apple procyanidins. Here is a summary of those findings:

• Total Number of Hairs: Significantly Increased

• Total Number of Terminal Hairs: Significantly Greater

• Increase in Hair Diameter: 78.9% Positive • Ratio of Thicker (terminal) Hairs: Significantly Higher

• Hair Follicle Activation: Intensive

In the most exciting development yet, Japanese researchers released a new study late in 2005. Once again, procyanidin therapy was proven successful in regrowing hair in subjects with male pattern baldness. The new study, published in the Journal of Cosmetic Dermatology, confirmed the findings of earlier studies, showing clear improvement in the number of hairs and the density of hairs in the treated area. Building on the success of earlier trials, the study was extended to 12 months in the procyanidin group, and proved that longer term procyanidin therapy was even more successful than prior 4 and 6 month trials.

Cooper Peptides - Cooper Peptides have two main properties: (1) potent tissue protective anti-inflammatory agents that limit oxidative damage after tissue injury, and (2) tissue remodeling activation agents, that is, the processes for removal of damaged protein and scar tissue and their replacement by normal tissue. Studies at numerous universities and research institutes have found copper-peptides to improve hair transplant success, increase hair follicle size, stimulate hair growth and reduce hair loss.

Research scientists at the University of San Francisco Wound Center stumbled upon very interesting results. Their discovery was made while applying a synthetically formulated compound, Copper Peptide, to severe wound areas on several patients. During this process something unusual Happened. Not only did the wounds heal about 30 percent faster, but a significant stimulation of the follicular cells occurred. As a side effect, these tripeptide complexes actually grew hair around the wound area.

The discovery was so startling that they then applied the same Copper Peptide complex to a female patient who had suffered roughly 90 percent alopecia (hair loss) for years. After about six months of use, she had recovered almost 100 percent of her hair. Dr. Loren Pickart, the leading authority in Copper Peptide technology, describes it as being like a protein injection to the scalp.

Tests were then conducted with chemotherapy patients and recent hair transplant recipients, all with great success in stimulating newer and stronger hair follicles.

Spin traps – are very special compounds that were originally utilized in measuring free radical activity because they react with free radicals both in vitro and in vivo, producing stable complexes. The most commonly used spin trap and the standard which measures new ones is PBN - alpha-phenyl- N-tert butyl nitrone. Hundreds of studies have been conducted over the last ten years that have tested PBN and other “spin traps” in numerous conditions. Later it was discovered that these spin traps had powerful free radical quenching abilities in living systems and could treat a variety of conditions. Spin traps could provide unique protection against free radical damage that complements and enhances the activities of the classical antioxidants such as vitamin C and vitamin E.

Spin traps modulate NF kappa-B regulated cytokines and inducible nitric oxide synthases that are implicated in pro-inflammatory disease conditions. A method for ameliorating a cellular dysfunction of a tissue such as the treatment of hair loss and stimulation of hair growth comprises administering a nitroso or nitrone spin trap to the affected tissue. These agents inhibit the reaction of superoxide and nitric oxide to produce peroxinitrite. Scientists discovered that nitrone and nitroso spin traps have properties in the body for ameliorating cellular dysfunction in tissue attributed, in part, to high energy oxygen and hydroxyl free radicals, and enhancing recuperation of the tissue. Alpha-phenyl-N-tert butyl nitrone (PBN) can be administered, for example, as an anti-alopecia agent to stimulate hair growth.

Spin traps can be administered to the skin to be treated, such as the scalp. Depending on the type of hair loss or alopecia being treated and the conditions thereof, the stimulation of hair growth can usually be obtained by topical application, preferably repeated daily application. The utility of topically applied spin traps is not limited thereto, however, and the stimulation of hair growth can include an increased rate of growth, increased hair diameter, follicular neogenesis, and the like; inhibiting hair loss or alopecia from progressing.

Ketoconazole - Topical ketoconazole shows itself to have an anti-DHT binding effect in the scalp. Nevertheless, it is likely that ketoconazole exhibits other methods to its anti-hair-loss effect. One such theory of ketoconazole anti-alopecia effects may be on its activity upon the removal of sebum, a fatty substance that accumulates in the scalp around the hair follicles. In addition, ketoconazole is an antifungal medication and is significant for people combating hair loss since acting as an antifungal agent it reduces scalp irritation caused by fungal colonization or infection. Reduction of the inflammatory process that occurs in male pattern alopecia is crucial.

If we first examine the role of androgens, specifically dihydrotestosterone (DHT), we find that this hormone has been thought to slowly "choke" the growth of the hair follicle by inhibiting the function of an enzyme in the hair follicle called adenylate cyclase. Suffice it to say that when DHT concentrations remain high in the scalp, we see terminal (thick, coarse) scalp hair become reduced to vellus hair (fine, thin peach fuzz). On March 04, 2001, at the American Academy of Dermatology Meeting in Washington DC, scientists presented the findings of a study done on 1% ketoconazole shampoo which had good news for hair loss sufferers. In the study presented, one hundred male volunteers with mild to moderate dandruff and somewhat oily scalp, were using in a double-blind fashion either a 1% ketoconazole shampoo or a 1% zinc pyrithione shampoo, 2-3 times a week for 6 months.

Analysis of the different parameters set up in the study shows that the hair diameter gradually increased with ketoconazole use (+8.46%) over a 6 month period, whereas the diameter showed a trend to decrease with zinc pyrithione use over the same period (-2.28%). The sebum excretion rate was reduced with ketoconazole (-6.54%) while it increased with zinc pyrithione (+8.2%) over the same period of time. The number of hairs shed over a 24-hour period was reduced by 16.46% with ketoconazole and 6.02% with zinc pyrithione after 6 months. Finally, the percentage of hairs in the anagen phase increased by 6.4% and 8.4% respectively during the study.

The results are similar to a previous study done on 2% prescription strength Ketokonazole where it was shown that use of 2% ketoconazol yielded an increase in hair shaft diameter similar to what was achieved by the control group using 2% Minoxidil and a non-medicated shampoo.

Rooibos - Rooibos or Red Bush Tea - a hardy shrub indigenous to the North Western Cape of South Africa – is an exciting new botanical ingredient with potent antioxidant and anti-inflammatory properties well documented in medical literature. In alternative medicine Rooibos is often prescribed for nervous tension, allergies, stomach and digestive problems. Results from an independent study also showed a significant improvement in hair loss. Studies were initiated at an independent laboratory (Dermascan, France) to study the effect of the use of Rooibos in a hair lotion on a group of healthy persons who were suffering from the problem of hair loss. A 90 day trial was conducted comparing a hair lotion containing Rooibos with a placebo lotion.

After 90 days results showed a significant increase of the hair growth in the lotion containing Rooibos compared with the placebo. An increase in the hair growth was observed with 89% of the volunteers with no undesirable reactions (irritation or allergy). The participants were next asked to fill in a questionnaire. When the results were tallied, 67 percent rated their hair loss as zero or low, 78 percent saw a low to medium improvement, 45 percent saw a low to medium regrowth of hair, and 63 percent considered their hair had become smoother and shinier.

Conclusion: results show that most of the volunteers had a remarkable improvement in both the increase of hair growth and the decrease in hair loss.

MSM - Sulphur is present in protein-rich foods containing high levels of the amino acids methionine and cysteine. These foods include meat, fish, legumes, nuts, eggs, and vegetables, especially onions. However, sulphur has recently become a popular nutritional supplement and topical treatment thanks to the discovery of methylsulfonylmethane, or MSM.

The use of MSM as a nutritional supplement and topical application is relatively recent. An American chemist named Robert Herschler, began studying MSM in 1955. However, another man, Dr. Stanley Jacob with Oregon Health Sciences University in Portland, is considered by many to be the father of MSM. Dr. Jacob found that simple marine life like algae and plankton convert inorganic sulphur to organic sulphur compounds. These compounds are known as dimethylsulfonium salts. These salts are transformed into dimethyl sulfide (DMS), which is released into the atmosphere and is converted by ultraviolet light into dimethyl sulfoxide (DMSO). When DMSO oxidizes, it turns into MSM and is absorbed by plants that become food for animals and humans. MSM is a white, crystalline powder that is odorless and nearly tasteless. When taken as a dietary supplement, MSM proved to have the same health benefits as DMSO without side-effects such as bad breath, itchy skin, nasal congestion, and shortness of breath. Why does MSM help with the development of stronger hair? Various scientific studies have proven that MSM contributes a definite normalizing effect on body functions. The sulfur normally provided to the body by MSM is required for healthy collagen and keratin which are essential for healthy hair, skin and nails. MSM also has proven antioxidant benefits which can disrupt or alter damaging chain reactions of lipid peroxidation in the cell membranes.

MSM has been widely used as a dietary supplement without any reports of allergy or intolerance related to its use. Supplements of MSM are comfortably assimilated without side effects. There are no known contraindications.

Caffeine 4% - Active caffeine ingredient helps to regulate the effects of testosterone levels. Male pattern baldness is known to occur in individuals with sensitivity to testosterone, causing damage to hair follicles that eventually leads to baldness. Caffeine is a xanthine alkaloid compound that acts as a stimulant in humans. Caffeine is a central nervous system (CNS) stimulant, having the effect of warding off drowsiness and restoring alertness.

The independent study at the University of Jena used hair samples from the scalps of young men entering into the first stages of hormone-related hair loss. The study relied on a hair organ culture that used four different types of testing samples. The first was a nutrient-based sample, the second a testosterone only sample, the third was a caffeine only sample and the fourth a mixture of caffeine and testosterone.

According to the research, the results showed that the samples containing the caffeine nutrient helped to stave off hair loss and encouraged new hair growth, while the sample that relied on testosterone only led to increased hair loss. But perhaps the most impressive was the testosterone and caffeine sample, which helped to prevent further hair loss.

The results showed that using the caffeine treatment average growth was increased by around 46 per cent and the life cycle of the hair was extended by 37 per cent, when compared to the control study.

Carnitine Tartrate - L-Carnitine, a vitamin-like nutrient, occurs naturally in the human body and is essential for turning fat into energy. Active energy metabolism is an essential prerequisite for the growth of strong and healthy hair. In biological systems ATP acts as the universal energy currency. One of the most potent bio-actives that significantly increases cellular ATP content is carnitine tartrate.

Statistical evaluation demonstrated a significant increase in ATP equivalents in human hair roots treated with carnitine tartrate, showing that carnitine tartrate is an ideal ingredient for hair care formulations, providing energy for the optimal environment to produce strong and healthy hair. Throughout the test period ATP content within plucked hair follicles was determined twice daily using a commercially available test kit. Statistical evaluation of baseline adjusted values demonstrated a significant increase in ATP equivalents in human hair roots treated with carnitine tartrate. These effects were absent in the placebo group, thus underlining the stimulating activity of carnitine tartrate.

The outstanding bio-activity of carnitine tartrate was furthermore demonstrated in a second study, assessing the effects after a single application of a shampoo formulation supplemented with carnitine tartrate. Again, ATP levels in plucked human hair follicles were significantly increased.

Amino Acids: Ornitine, Taurine, Cysteine - Amino acids are the building blocks of protein, from which hair is created. They are assembled in the correct sequence by stem cells to form keratin, a complex and immensely strong hair protein. Vital amino acids have to be replaced consistently, as damage is accumulated over time. We can replace a combination of these lost amino acids directly into the hair, where they are shown to provide significant tensile benefits to the hair shaft.

Hair is composed primarily of proteins (88%). These proteins are of a hard fibrous type known as keratin. Keratin protein is comprised of what we call "polypeptide chains.” The word, polypeptide, comes from the Greek word "poly" meaning many and "peptos" meaning digested or broken down. In essence, if we break down protein, we have individual amino acids.

Many (poly) amino acids joined together form a "polypeptide chain". Two amino acids are joined together by a "peptide bond", and the correct number of amino acids placed in their correct order will form a specific protein; i.e. keratin, insulin, collagen and so on. The "alpha helix" is the descriptive term given to the polypeptide chain that forms the keratin protein found in human hair. Its structure is a coiled coil. The amino acids link together to form the coil and there are approximately 3.6 amino acids per turn of the helix (coil). Each amino acid is connected together by a "peptide bond". The peptide bond is located between the carbon atom of one amino acid extending to bond with the nitrogen atom of the next amino acid. In many individuals the extremities, including the top of the head, are the most difficult places to maintain blood flow. Follicles which are constantly deprived of blood, and therefore nutrients, cannot produce hair properly. Lack of proper nutrients, amino acids, minerals and vitamins can certainly hamper hair growth.

L-Arginine is a semi-essential amino acid synthesized by the body from L-Ornithine. Arginine + Ornithine support protein synthesis because they are involved in the transport and storage of nitrogen. The usage of taurine corrects the "rigidification" of the connective sheath that surrounds the Pilosebaceous unit and hair follicles, specifically those affected by pattern hair loss. This is a novel and previously undisclosed angle on hair loss treatment that has yet to be touched upon in any of the medical literature or prior publications.

The amino acid, l-cysteine speeds up hair growth and increases hair shaft diameter resulting in fuller hair. L-cysteine has been reported to facilitate longer hair growth, beyond what is genetically programmed. L-cysteine also provides potent antioxidant protection to the hair follicle. Users of topical n-acetyl-cysteine have reported hair regrowth.

Emu Oil - The emu, dromaius nova hollandiae, is a flightless bird part of a group called ratites which also includes the ostrich and the kiwi. Modern Australians learned early on from the Aborigines the many valuable qualities in the emu and its oil. The earliest research studies in emu oil come from Australia, and Australia continues to export emu oil to this day.

In the United States today there is a growing network of research labs interested in emus and their incredible oil. Emu oil is rendered from a thick pad of fat on the back of the bird that was apparently provided by nature to protect the animal from the extreme temperatures in its Australian homeland. Emu oil is deep penetrating and super hydrating to the skin - an all-natural tissue nutrient. Michael Hollick, MD, Ph.D., Professor of Medicine, Physiology, and Dermatology at Boston University School of Medicine conducted a study involving emu oil and hair growth. His study found that there was a 20% increase in growth activity of skin that received emu oil compared to skin that received corn oil. Looking at the hair follicles Dr. Hollick realized they were much more robust, the skin thickness was remarkably increased suggesting that emu oil stimulated skin growth and hair growth. Additionally, the study showed that over 80% of hair follicles that had been "asleep" were woken up, and began growing.

Emu oil is anti-inflammatory, which may be in part why it stimulates hair growth. Emu Oil has also been shown to be a 5 alpha reductase inhibitor in target tissues when topically applied, which likely contributes significantly to its hair growth properties. A third important property of emu oil is that it is bacteriostatic.

Emu Oil contains a multitude of Essential Fatty Acids (EFA) which helps to "feed" the skin. Consumers who suffer from natural forms of baldness have reported hair re-growth. Since Alopecia Areata only suppresses the hair follicle (vs. killing the hair follicle), emu oil may have an effect to assist with hair regrowth.

Biotin – Biotin is a member of the B-vitamin family and a major component in the natural hair manufacturing process -- it is essential to not only grow new hair, but it also plays a major role in the overall health of skin and nails. The beneficial effects of biotin on hair may be linked to its ability to improve the metabolism of scalp oils. Biotin when absorbed by the scalp may promote hair growth and it is able to penetrate the hair shaft making it expand which actually thickens the hair cuticle.

Biotin is used in cell growth, the production of fatty acids, metabolism of fats and amino acids. It plays a role in the Krebs Cycle, which is the process in which energy is released from food. Biotin is so important to hair health, that many dermatologists prescribe biotin supplements to their patients as part of their medical treatment for hair loss.

After applying Revita with a gentle massage, you should leave it on the scalp from 1 – 2 minutes before rinsing. Then repeat and leave on the scalp for 3 – 5 minutes. If desired, follow with a high quality conditioner. For optimal results, Revita should be used at least 5 times per week.

This formulation is contraindicated in individuals with a history of sensitivity reactions to any of its components. It should be discontinued if hypersensitivity to any of its ingredients is noted.

Q. Is Revita safe ?

A. Revita primarily contains compounds that are not only safe in topical use, but actually dramatically enhance overall skin health. The other active ingredients such as Ketoconazole have been tested in clinical studies and have been shown safe.

Q: Can I use hair sprays, mousses, gels, etc.?

A: Hair spray, gel, and other styling aids are not recommended since they tend to clog the hair shaft. However, you can use them while using Revita.

Q: Can I have my hair colored or permed while using Revita ?

A: While there is no evidence that coloring or perming hair can lead to or even worsen hair loss, it is generally not recommended for people with hair loss. If you are experiencing hair loss then perming and coloring hair is not recommended. However, this will not interfere with Revita.

Q: What is SLS/SLES free ?

A: SLS means Sodium Lauryl Sulfate and SLES means Sodium Laureth Sulfate, commonly used low cost detergents in shampoos and cleansers. They are linked to skin irritation, skin drying and hair loss due to follicle attack. Revita is Sodium Lauryl Sulfate and Sodium Laureth Sulfate free, and that means that Revita does not irritate you scalp and preserves your hair follicale health.

Q: Can I blow dry my hair after using Revita ?

A: Extreme heat damages the proteins in the hairs making them fragile. Nevertheless, if you need or want to blow dry your hair, you can do it after using Revita.

Q: Who is a candidate for Revita ?

A: Ideal candidate is someone with little hair loss or at the beginning stages of hair loss, since it is much easier to prevent hair loss then to grow new hair. Someone who is concerned with hair loss prevention should start using Revita immediately.

Q: What type of results should I expect with Revita ?

A: When deciding to use Revita, it is important to have realistic expectations. Depending of severity and duration of your hair loss, it could take some time to see hair growth. In fact, during the first 2 weeks of treatment you may actually notice increased hair loss as old hairs are being pushed out and the hair follicles start growing new hair. Do not become alarmed with this and just stick to the treatment.

Q. Does Revita have any systemic side effects ?

A. No, when used as directed, Revita active ingredients have a long history of use both orally and topically.

Q. Does Revita work for women?

A. Yes. In most cases, the cause of hair loss in women is surprisingly similar to men. Fortunately for women, estrogen helps to protect the hair follicle from the destructive effects of DHT. However, many women develop thinning hair and loss due to fluctuation of estrogen levels and/or over production of DHT. Revita can help protect the hair follicle from DHT resulting in a thicker, fuller and healthier hair.

Q. I am using other topical treatments. Can I use Revita at the same time ?

A. Yes. Revita has no side effects and does not cross react with other topical treatments. You can safely opt to use Revita with other products, and we strongly recommend the association with Spectral.DNC for more severe hair loss or Spectral.RS for thinning hair.

Q. Do I need to use Revita for a long time ?

A. Once you have reached the desired results, you should continue to use Revita as your regular shampoo to maintain the revitalized hairs and a healthy scalp.

Q: Is stress a factor in hair loss?

A: When the body is under significant physical and emotional stress it is possible that the immune system will produce anti-bodies that attack hair follicles, and this results in bald patches or diffuse loss. Stress-induced loss will respond very well to Revita and you should keep using Revita as your regular daily shampoo to keep your scalp healthy.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1480)

Date: November 22, 2006 01:43 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Q. Why not just take IP-6 by itself? Why does IP-6 need to be combined with inositol?

A. When scientists studying this combination used plain IP-6 in the laboratory, good cancer preventative effects and good cancer killing effects Happened. When scientists used plain inositol in the laboratory, again, good cancer preventative and cancer killing effects occurred. However, when IP-6 was combined with inositol, powerful cancer killing and cancer preventative effects Happened. Clearly, IP-6 with inositol is the superior choice in cancer prevention.

Scientists are interested in the very unique way IP-6 works in our body. One theory of how this combination exerts its effects is that IP-6 mixed with inositol breaks down into IP-3 in the body. IP-3 is more active than IP-6, but is very unstable. That is why it is so important to use a product that is an exact combination of IP-6 and inositol, precursors that are both needed to yield the maximum amount of IP-3 needed for immune stimulation and cancer growth inhibition.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1430)

Date: November 22, 2006 01:31 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Cancer, The Immune System, and Nutritional Supplements

This is a tale of three discoveries. One transpired deep in the rainforests of Peru. Another Happened high in the mountains of Japan. And the third discovery occurred in a university on the East Coast of the United States.

All of these discoveries resulted in amazing all-natural nutritional supplements. All of these nutritional supplements have powerful effects on the human immune system. And, while each of these natural nutritional supplements help prevent and treat immune diseases individually, together they may work even more powerfully to help strengthen our immunity and keep us cancer-free.

In this issue of Ask the Doctor, we will learn about these three important natural discoveries: namely, POA cat’s claw root, maitake mushrooms, and IP-6 with inositol. We will discover for ourselves how these all-natural supplements work directly on specific cells of the immune system to protect us from cancer and boost our immunity.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1422)

Date: September 19, 2006 05:43 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Educator in Glyconutrient Technology and Cellular Restoration

Come along and share some thoughts with me about how we can prevent a lot of misery from illness and disease. Not everyone cares about this, but I hope you do.

When a doctor says “we got it all”, it usually comes after cancer surgery. Why then do we have to go through chemo therapy, radiation and drugs to prevent it from coming back? What caused it to ever have Happened in the first place? When my mom got breast cancer, she dutifully took Tamoxifen for 12 years and died of liver cancer. She blamed the drug, but what was missing before she got cancer? Science has discovered a new technology that will change the world of health. It’s called glyconutrients and is the missing link in our diets today. This is not just another food supplement, it is a vital food!

Glyconutrients do not heal cancer. If you have a strong immune system though, you can avoid or repair disease. The body wants to be well and does everything with what it has to keep you well. These 8 sugars are so vital to keep your cells communicating and building strong stem cells. Adult stem cells were harvested from approximately one half pint of a patients’ own blood to treat several heart conditions. Treatable heart conditions are: coronary artery disease – Cardiomyopathy- heart failure – severe angina pectoris. We are talking about an adult stem cell transplant! My body is producing new adult stem cells every day and is restoring, defending, protecting and repairing my health from all kinds of ailments.

Researchers who study this cellular communication proclaim it to be the most important discovery in the history of medicine… the key to a long, healthy life!

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1383)

Date: July 08, 2006 01:55 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Product Resurfaces under a new name - from HSI - Health Sciences Institute

You may remember the outrageous ruling resulting scandal surrounding Lane Labs MGN3 product back in july 2004. essentially, the FDA forced the company to stop selling the product—not because it was dangerous or ineffective but because the FDA felt that Lane Labs marketing language made disease clams allowed only for FDA-approved drugs.

When that Happened, everyone who had experienced great results with this immune system booster (including many HSI members) suddenly found themselves without a safe and effective product they could rely on. So we promised that we would keep a lookout for a natural and effective therapy that would provide similar benefits to the outlawed MGN3 formula.

But we’re officially calling off the search. A new product called PeakImmune4 was introduced in july 2005. but as it turned out, Peakimmune4 really isn’t new at all. It actually contains the same active ingredients as MGN3—it’s just being sold by a different company under a different name.

When products change names and hands, it can be co concerting. And I have to admit that at first, this seemed kind of fishy to me. so I did some digging to find out if Peakimmune4 was really all it was cracked up to be. What I realized at the end of this winding trail was that to best understood the story, you need to start at the beginning.

Connecting the dots

In 1992, Daiwa Pharmaceutical began developing Rice Bran Arabinoxylan Compound (RBAC). RBAC does right to the source of ultimate health: your immune system. Human clinical studies have proven that RBAC can more than triple the activity of Natural Killer cells, the body’s first line of defense against disease like cancer, HIV, and hepatitis. Studies also show that RBAC increases two other vital immune system cells: T cells and B cells.

Daiwa, which is based in Tokyo, Japan, licensed this patented formula to Lanes Labs, which sold it in the U.S. under the trademark MGN3. (We first told you about it back in 1999 in the June Issue of your Members Alert). But then in July 204, the government stepped in and barred Lane Labs from selling MGN3 (in addition to two other products). The FDA did not, however outlaw RBAC, the compound from which the product was make.

Daiwa, was left with a great product but no way to market it in the U.S. that’s when they decided to branch out and open their own company in the states, Daiwa Health Development, so they could continue to offer RBAC and introduce other Daiwa supplements to the market.

In July 2005, Daiwa launched Peakimmune4. it may be hard to find a connection between these two products because you wont find MGN3 mentioned in any of Peakimmune4’s promotional materials. That’s because the court did more than just forbid Lane Labs from selling MGN3. it also stipulated that the MGN3 brand name could not be used in marketing and promotion of supplements made from the same active ingredient, and that products could not be promoted as a replacement or substitutes for MGN3.

However, you can rest easy knowing that this product uses the same active as MGN3, which means the same solid research backs it up.

Recommendations for healthy immune system

Many immune system products require you to cycle on and off. But since Peakimmune4 does not lose effectiveness over time and doesn’t cause the immune system to attack itself, you can take it regularly without worrying about side effects.

Dr, Martin Milner, medical adviser to HIS, has used the RBAC compound for years. He has monitored its effectiveness in his own patients by testing their NK cell response. Milner confirmed clinically that his patients have retained increased levels of NK cell activity even when they used the product for prolonged periods of time.

For the best results, you should follow two simple steps: first, take four capsules three times a day for four weeks (before or after a meal). Then, after four weeks reduce dosage to the maintenance level of four capsules daily. You can find Peakimmune4 at most health food and vitamin stores. And don’t be surprised when it pops up in your doctor’s office under the name BRM4.

If you decide to try Peakimmune4 to support your immune system health, you should work with your health care professional, especially if you are pregnant, are nursing, are being treated for any medical condition, are currently taking medications, or have been diagnosed with a health disorder. And if you are taking immunosuppressant drugs for an organ transplant, you should NOT take a product with RBAC in it, each capsule contains 250mgs of Rice Bran Arabinoxylan Compound (RBAC). HSI www.HSIBaltimore.com

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1329)

Date: December 19, 2005 08:47 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: GliSODin Anti-Aging and Antioxidant Protection

GliSODin Anti-Aging and Antioxidant Protection

• Superior Anti-Aging Formula
• Stimulates Natural Antioxidant Defenses
• Helps Protect DNA
• Reduces Oxidative Stress
• Prevents Oxygen Related Cell Damage

In the time it takes you to finish reading this article, you, your body and your cells will have aged. Some, more than others. Nevertheless, every second that ticks away should serve as a reminder that our time here is temporary. How much time we actually end up with depends on many things. Diet. Lifestyle. Environment. Superoxide Dismutase? I’ll explain. What some of the healthiest individuals fail to realize is that our bodies age from the inside out. Aging is not the result of passing time, but rather the result of what we’re exposed to environmentally, physically and chemically. It is the integrity of our cells, not our clocks, that determine how smooth the aging process fares.

Each day, we’re subjected to millions of elements that affect us in ways seldom seen, felt or noticed. From the moment we’re born, we rely on our cells to work around the clock - producing energy, fighting infections and sustaining life. These same cells eventually determine the rate at which we show (or hide) our age.

Taking into consideration that our planet has no shortage of toxins & germs, the need to safeguard our cells becomes very real. Constant exposure to exhaust, secondhand smoke, heavy metals, lead, fluoride and uncountable other noxious compounds should ideally provide us with nothing more than a routine immune system workout. Unfortunately, over long periods they hinder our “resistance” abilities and become stepping stones to accelerated aging.

Antioxidants. We’ve all heard the term before, and may even have a general understanding of their role. But to better grasp just how vital they are, it helps to know what’s happening at the cellular level. Free radicals are unstable molecular thieves that often lack electrons. To compensate, they rob healthy cells - a process better known as oxidation. Antioxidants work with the immune system to prevent oxidation, and clean up the mess it leaves behind. Hence, the name.

There are two types. Exogenous antioxidants are derived from our diet and include vitamins A, E, and C along with others such as alpha lipoic acid, selenium, CoQ10, grape seed, pycnogenol and zinc. To date, we’ve been limited to exogenous antioxidants as a way to increase the rate at which our body wards off oxidation. They are not, however, our first line of defense. At birth, each and every one of us is equipped with three primary endogenous enzymatic antioxidants; SOD (Superoxide Dismutase), Glutathione Peroxidase (GPx) and Catalase.

While both types of antioxidants are beneficial, we’ve become reliant on those from the diet to compensate for our inability to boost the effectiveness of our 3 primary antioxidants. For years, researchers have been examining ways to enhance the activity of our built-in bodyguards. One in particular, Superoxide Dismutase (SOD) has been of foremost interest. SOD targets what many researchers regard as one of our greatest health threats and aging accelerators - Superoxide radicals. These highly reactive, merciless molecules incite enormous amounts of oxidative stress and are capable of wreaking havoc on healthy cells. When cells are left unprotected by SOD, the results can be disastrous - respiratory problems, premature aging, memory loss, cardiovascular challenges, vision failure and joint structure damage, among others.

Until now, we’ve been at the mercy of our natural SOD reserves to fight superoxides. Researchers have been working feverishly to produce an effective oral SOD supplement, but have continually encountered a frustrating hurdle - exposure to gastric acid denatures SOD, rendering it useless. As a result, the only effective way to supplement SOD was through injections. These, however, only yielded short-term spikes. And then something remarkable Happened that changed everything. Nutrition scientists in France determined that by combining Cucumus melo (a melon high in SOD) with a wheat gliadin stabilizer, it would be possible to prevent SOD from deteriorating in the digestive tract, while preserving it in the blood for extended periods. Not only is this the answer to a puzzle that has plagued researchers, it’s a breakthrough that will impact the life of anyone seeking longevity and vitality.

As the first proven oral SOD supplement ever introduced to the public, GliSODin® has taken antioxidant protection, immune support and antiaging science to an entirely new level. The primary function of GliSODin® is to scour the body for superoxide radicals and reduce them to less reactive ions that can be swept away; a process known as dismutation. In addition, GliSODin® reduces the oxidation vulnerability of healthy cells, protects mitochondrial activity and safeguards DNA structure.

What’s most remarkable is that GliSODin® has actually been shown to stimulate the body’s own natural production of all three enzymatic antioxidants, including SOD. For the first time in history, we will have the ability to enhance the effectiveness of our body’s primary defense mechanism.

New GliSODin® from NOW® represents the ultimate in antioxidant protection. By increasing one’s level of SOD while stimulating the natural production of Glutathione Peroxidase and Catalase, GliSODin® delivers antioxidant protection unlike any previously released dietary supplement. Remember, the aging process begins at a level that we simply can not see, the cellular level. Shielding your cells from superoxide damage is one of the smartest steps you can take against aging before your due time. GliSODin® has made this a reality.

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Buy GliSODin at Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1037)

Date: November 11, 2005 06:30 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Why does IP-6 need to be combined with inositol?

Q. Why not just take IP-6 by itself? Why does IP-6 need to be combined with inositol?

A. When scientists studying this combination used plain iP-6 in the laboratory, good cancer preventative effects and good cancer killing effects Happened. When scientists used plain inositol in the laboratory, again, good cancer preventative and cancer effects occurred. However, when IP-6 was combined with inositol, powerful cancer killing and cancer preventative effects Happened. Clearly, IP-6 with inositol is the superior choice to cancer prevention.

Scientists are interested in the very unique way IP-6 works in our body. One theory of how this combination exerts its effects is that IP-6 mixed with inositol breaks down into IP-3 in the body. IP-3 is more active than IP-6, but is very unstable. That is why it is so important to use a product that is an exact combination of IP-6 and inositol, precursors that are both needed to yield the maximum amount of IP-3 needed for immune stimulation and cancer growth inhibition.

--
Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=939)

Date: August 12, 2005 11:10 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Omega Man - For Men Interested in Optimal Health

Omega Man

For Men Interested in Optimal Health, Vitality and Staying Young

Scientists have discovered the key that unlocks the door to a longer life, healthy weight, optimal athletic performance, and overall well-being. That key is composed of essential fats, called omega-3 fatty acids. You need these fats to balance the effects of the male hormone testosterone. Found in flax, pumpkin seeds, and other plants, omega-3 fats are essential to well-being, vitality, and optimal fitness; yet most men are deficient in the omega-3s.

The low-fat and nonfat fads of the 1980s and 1990s taught nutrition experts a lot about the importance of omega-3 fats. As food manufacturers created one nonfat product after another, a strange thing Happened- men got fatter and heart disease rates jumped.

Since then, experts at research institutions including Harvard and the National Institutes of Health (NIH) have linked nonfat diets with depression, heart disease, weight gain, and poor physical performance.

We now know that all fats are not created equal. Although some fats are indeed bad for our health, other fats are essential to overall health, vitality, and well-being. Most men, however, over consume the wrong fats- those found in processed foods and animal products- and do not consume enough of the right fats. To make matters worse, the good omega-3s are dwindling from the food supply. Food processing has stripped this important fat from our foods, making supplementation necessary.

Thankfully, Omega Man from Barlean’s Organic Oils, a new whole food concentrate for men, will help reduce the risk of some of the most deadly and common men’s health problems. All men will benefit from Omega Man. Its blend of essential fats from flax, Styrian pumpkin seeds, and other sources complement one another, providing the optimal mix of the right types of fats, which promises to promote health and vitality no matter what your age.

From the athletic pursuits of your early twenties to the health concerns of your fifties and beyond, Omega Man is an important part of a man’s healthy diet and will unlock the door to a new, more vibrant, healthier you.

Recently, we’ve begun to report on the importance of certain men’s power foods and nutrients. By putting optimal amounts of these into men’s diets, men can ensure greater health and longevity.

Super Health Blend

Omega Man’s unique blend of flax, pumpkin and other fatty acid sources is an optimal formula for men’s health and vitality.

Organic Flaxseed Oil

Barlean’s award-winning organic omega-3 and lignan-rich flaxseed oil makes up the base of this formula and provides the richest and best-absorbed source of omega-3 fatty acids available. Other popular sources of omega-3 fatty acids, such as fish oil, may contain contaminants such as mercury and industrial chemicals. Barlean’s flaxseed oil, on the other hand, comes from organic seeds grown in optimal conditions with no chemicals, pesticides, or other contaminants. You can feel safe knowing that all of Barlean’s flaxseed oil products, including Omega Man, are pure and fresh. They help you promote optimal health without polluting your body.

Lignans

In addition to omega-3 fatty acids, Barlean’s lignan-rich flax oil is one of the world’s richest sources of lignans, important plant chemicals that act like hormones in the body. Lignans have been shown to bind to existing hormones in the body, bringing your hormones into the optimal balance needed for good health. Few men consume the amount of lignans needed to promote hormonal balance, making supplementation so important.

Lignans serve in the body to block two critical enzyme systems that serve to initiate prostate cancer and benign prostatic hyperplasia. The first is aromatase, an enzyme that converts testosterone to a powerful testosterone derivative that is five times more powerful than its precursor in promoting prostatic disease. The second is 5-alpha reductase, and enzyme that converts testosterone to estrogen. Despite popular belief, estrogen is much more powerful in provoking prostate disease than testosterone. In fact, the ratio of testosterone to estrogen begins to weigh in favor of estrogen in the aging male. As testosterone levels decline with age, estrogen levels appear to remain relatively stable. Compared to younger men, the ratio of estrogen to testosterone is up to 40 percent higher in older men.

Breakthrough research is implicating the imbalance between testosterone to estrogen as a primary cause of prostate disease. Flying in the face of past misconceptions, it would actually serve the aging male to increase testosterone at the expense of estrogen. It appears that this is exactly what lignans do in blocking the enzyme necessary for converting testosterone to estrogen. When the enzyme is blocked, testosterone is spared because it is not being converted to estrogen. In what you could visualize as a seesaw-like action, the ratio of testosterone to estrogen begins to move back in favor of testosterone.

The action of lignans in sparing testosterone may hold greater implications than the obvious. Lack or loss of sexual desire in men and women is oftentimes associated with low testosterone levels. By preserving testosterone, many men and women may be able to retain or regain their sexual vigor. In fact, agents that block the conversion of testosterone to estrogen have been showing to increase testosterone levels by as much as 10 percent. (Speaking of sexuality, the surgical treatment of choice for prostatic disease (prostectomy) is the leading cause of impotency in men over 50. This fact alone should be powerful motivation for men of all ages to consider a supplemental regime to include lignans to lower the incidence of prostate cancer and benign prostatic hypertrophy.)

The full significance of a “high-in-lignan” diet may be realized by the fact that lignans have been found isolated within prostatic fluids. Analytical work performed at a prominent cancer research center has indicated that the level of lignan in expressed prostatic fluid can be remarkable high, suggesting that it could well exercise a physiologic role within the gland. The glandular cells are certainly bathed in prostatic secretion for some considerable period, during which they could well influence cell biology. It has been established that the higher the intake of dietary lignans, the higher the physiologic lignan concentration in urine, blood plasma and prostatic secretions. The inference here is that the more dietary lignans that are ingested the more protection is offered in bathing the prostate gland in fluids high in protective lignans.

Styrian Pumpkin Seed Oil

Barlean’s went to the edge of the earth to procure the seeds of a rare and unique pumpkin found only in the region of southeast Austria. It is reputed for its extraordinary wealth of vitamins A, C, E, and K and high levels of phytosterols, all important for reducing risk of enlarged prostate and in the fight again cancer and heart disease.

Phospholipid Concentrate

Nearly every part of your body, from your internal organs to your cell membranes to your brain, contains phospholipids. Phospholipid supplementation has been shown to promote heart, digestive, liver, and brain health. Omega Man contains the optimal amounts of phospholipids for your health.

Plant Phytosterol Complex

Omega man is a rich source of the plant phytosterols betasitosterol, campesterol, and stigmasterol. If men have not begun to put phytosterols into their diet, then they’re missing out on an important natural food constituent that offers protection against toe most common cancers, that is an excellent remedy for enlarges prostate, and lowers cholesterol. Phytosterols are used widely in Europe to treat enlarge prostate (benign prostatic hyperplasia) and are known to lower the risk of cardiovascular disease by interfering with cholesterol absorption. Omega Man contains an optimal blend.

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Vitanet ®

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Date: July 15, 2005 12:24 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: STEVIA (Stevia rebaudiana)

STEVIA (Stevia rebaudiana)

SYNONYMS: sweet herb, honey leaf

PARTS USED: leaves

Description

Stevia is a small perennial shrub with green leaves that belongs to the aster (Asteraceae) or chrysanthemum family of plants. They grow primarily in the Amambay mountain range of Paraguay but over 200 various species of stevia have been identified around the globe. Stevia rebaudiana is the only species at present which possesses an inordinate ability to sweeten. Its common form is known as stevioside, a fine white powder extracted from the leaves of the plant. Phytochemistry STEVIOSIDE/REBAUDIDOSIDE COMPOUND DUO: The leaves of the stevia shrub contain specific glycosides which produce a sweet taste but have no caloric value. Stevioside is the primary glycoside involved in this effect. Dulcoside and rebaudioside are also major glycosides contained in the herb. Glycosides are organic compounds which contain a sugar component (glycone) and a non-sugar component (aglycone). The glycone constituent may be comprised of rhamnose, fructose, glucose, xylose, arabinose etc. The other portion may be any kind of chemical compound such as a sterol, tannin, carotenoid, etc.

Stevia leaves also contain protein, fibers, carbohydrates, phosphorus, iron, calcium, potassium, sodium , magnesium, rutin (flavonoid), iron, zinc, vitamin C and vitamin A. Human physiology cannot metabolize the sweet glycosides contained in stevia leaves, therefore they are eliminated from the body with no caloric absorption. Stevia, unlike aspartame, can be used in baking because its sweet glycosides do not break down when heated. Definition Stevia is an herb with incredible sweetening power. Its ability to sweeten is rated between 70 to 400 times that of white sugar. Typically, it has a mild licorice-like taste and is completely natural in its biochemical profile. What makes stevia so intriguing is that unlike other natural sweetening agents, its is completely calorie-free, never initiates a rise in blood sugar, and does not provide “food” for microorganisms like bacterias and yeasts.

Stevia may well be the most remarkable sweetener in the world and yet its recognition in this country remains relatively low. Consider the extraordinary attributes of the stevia plant and its extracts:

• It can be used in baking and cooking.

A Brief History

Stevia is a plant indigenous to mountainous regions of Brazil and Paraguay. For centuries, this herbal sweetener has been used by native cultures to counteract the bitter taste of various plant-based medicines and beverages. The Guarani Indians of Paraguay have used this potent sweetener in their green tea for generations. The name they designated for stevia leaves was “sweet herb.” In addition, these native peoples have historically used stevia as a digestive aid and a topical dressing for wounds and other skin disorders.

In the sixteenth century, Europeans became aware of the herbal sweetener through the Spanish Conquistadors. In the late 1880s, Moises S. Bertoni, director of the College of Agriculture in Asunción, Paraguay, became extremely intrigued by the stevia plant. Its reputation was that it was so sweet that even just a small leaf part could sweeten an entire container of mate tea. Be rtoni wanted to find out if this was true. After several years of studying the plant, he wrote about it in a local botanical publication. In 1905, Bertoni published an important article about the incredible sweetening power of the stevia plant, which he considered superior to sugar and extremely marketable. Other articles written by Bertoni note that stevia is unquestionably superior to saccharine because it is nontoxic and has significant therapeutic benefits. It sweetens with unprecedented potency and can be used in its natural state.

The first stevia crop was harvested in 1908 and subsequently, stevia plantations sprang up in South America. In 1921, the American Trade Commissioner to Paraguay, George S. Brady, wrote that although the herb is an extraordinary sweetener with remarkable properties, little had been done to commercially cultivate the plant. He suggested that stevia may be an ideal sugar product for diabetics and strongly advised that American companies pursue its importation.

During the decade of the 1970s, the Japanese developed a new method which could better refine the glycosides contained in the stevia leaf. The result was a compound called ste-vioside which is from 200 to 300 times sweeter than white sugar. The Japanese approach artificial sweeteners with great caution and they believe stevioside to be safer and more effect i've than other non-nutritive, chemical products. Stevioside is considered superior in its ability to sweeten; however, it does not exhibit some of the other therapeutic actions found in whole stevia leaves .

Stevia enjoyed substantial popularity during the 1980s as a natural sweetener and was found in a variety of consumer products. In 1986, however, the FDA abruptly seized stevia inventories and in 1991 claimed it was not suitable as a food additive. Advocates for stevia claim this Happened because the herb is a natural, powerful, inexpensive and non-patentable sweetener, and therefore poses a threat to pharmaceutical sweeteners and sugar-alcohol sweeteners like mannitol, sorbitol and xylitol. At this writing, stevia has received approval by the FDA to be sold only as a dietary supplement, not as a sweetening agent.

Currently, stevia is commercially grown in Paraguay, Brazil, Uruguay, Central America, Israel, China, Thailand, and the United States. It is considered an important natural sweetener in both Japan and Korea, and has been safely used in these countries for decades. Extracts of stevia and related products make up a considerable portion of the Japanese market for natural sweetening agents. They use stevia in sweet sauces, pickles, beverages, etc., making Japan one of the largest single consumers of stevia in the world. Today, because the demand for stevia is escalating, several Paraguayan organizations are looking to expand the commercial cultivation of the plant. Currently, Canadian researchers and chemists are working to provide even better stevia supplements and may even end up teeming with governmental agencies to raise stevia crops as economic replacements for tobacco leaves (Bonvie, 64). Stevia has not been officially approved by Canadian agencies, but it is still available for purchase in tea form.

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Your Healthy Harvest

Date: June 14, 2005 11:05 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Your Healthy Harvest

Your Healthy Harvest by Marjorie Flakowitz Energy Times, August 15, 2004

Once frowned on by conventional farmers, organic food has won respect from everyone concerned about the health of both the earth and the people who inhabit it.

Today, organic farming is considered one of the most rapidly growing areas of American agriculture. Organic foods sales topped $9 billion in 2002 and grew about 20%, up to almost $11 billion in 2003 (Organic Trade Association).

So when you buy organic, you join an expanding market that takes advantage of great-tasting, good-for-you food. Long ago, when the practice of farming was first devised, all farming was organic farming. So today's organic movement is bringing farming back to its roots.

But, safe to say, that is not what's motivating most consumers. A main reason for the popularity of organic food derives from the reassurance that organic foods, raised without artificial chemicals and pesticides, cut your exposure to toxic residues. A growing body of research shows organic food is richer in beneficial natural substances, too.

" Organic food and organic farming represent a philosophy that goes beyond just the quality of the food," says Steve Meyerowitz in The Organic Food Guide (Globe Pequot). "It strives to maintain the integrity of the entire food chain-plants, soil, air, water, animals and people. We are all part of the same ecosystem."

By eating organic, you eliminate pollution both from your body and the earth. Because our bodies are made of the animal and plant products we consume, our internal, physiological ecosystem and the earth's environment are inexorably entwined.

Chilling Arctic Evidence

As evidence of this connection, consider what's Happened in the Arctic. Researchers who have analyzed Arctic water, ice, snow, soil and plants have found that chemicals used in farming and industry in other parts of the world have traveled north and accumulated in alarming quantity. How and if these chemicals break down depends on sunlight and the amount of organic matter contained in Arctic waters (American Chemical Society, 9/11/03).

" Once pollutants enter the water column, their behavior is poorly understood-particularly the processes that govern their lifetime and concentrations," says Amanda Grannas, PhD, a researcher at Ohio State University. "Such pollutants are now being found in wildlife, from fish to seals to whales, and even in people living in the Arctic."

Dr. Grannas and others looked at the pesticides lindane and hexachlorobenzene (HCB), two chemicals that have migrated to Arctic waters. Lindane is used by American farmers to treat seeds before they are planted. HCB, banned in the US in 1984, is still used in other countries to protect wheat from fungus.

The scientists found that sunlight at the top of Arctic waterways can help break down some pesticides. At lower depths, however, cut off from the sun's rays, pesticides can remain largely intact. In this research, lindane proved to persist much more readily than HCB.

" Lindane is one of the most persistent of pollutants," warns Dr. Grannas. "This could be because it's photochemically inert, whereas pollutants like HCB degrade relatively quickly. The main message is that pollutants can behave quite differently. These pollutants already affect local ecosystems, and could have repercussions for human health."

Organics Means More Benefits

Researchers are also finding that organic produce contains larger quantities of beneficial natural chemicals. For instance, one study (Journal of Agriculture and Food Chemistry 2/26/03) showed that berries and corn grown organically can have almost 60% more polyphenolics. Polyphenolics are antioxidants plants use for protection against disease and which are good for humans. Researchers believe that when crops are grown conventionally, protected by pesticides and herbicides, they produce fewer of these substances. " This really opens the door to more research in this area," says Alyson Mitchell, PhD, assistant professor of food science at University of California at Davis, who led the research.

These scientists compared levels of total polyphenolics and vitamin C content in marionberries (a type of blackberry) and corn grown organically, sustainably or conventionally, and also looked at chemicals in strawberries grown either sustainably or conventionally. (Sustainable farming falls between the organic and conventional methods, and concentrates on farming that's self-sufficient-for example, feeding cows hay you've grown yourself, and then using the cows' manure to fertilize another crop.) They found that organic marionberries and corn had 50% to 58% more polyphenolics. The sustainably grown strawberries had 19% more polyphenolics. And all the organic produce contained more vitamin C.

Self-Defense for Plants

According to Dr. Mitchell, the organic crops contained the high levels of polyphenolics you'd expect to find in wild plants, suggesting that, on conventional farms, pesticides reduce the necessity for plants to make these protective, natural chemicals. " If an aphid is nibbling on a leaf, the plant produces phenolics to defend itself," she says. "[P]henolics guard the plant against these pests."

Pesticides kill insects like aphids and thereby reduce the antioxidants produced by the plant. " This helps explain why the level of antioxidants is so much higher in organically grown food," Mitchell says. "By synthetically protecting the produce from these pests, we decrease their need to produce antioxidants. It suggests that maybe we are doing something to our food inadvertently.

" We know [polyphenolics] are beneficial [to human health], but we don't know what types of polyphenolics are beneficial, or in what quantities," Dr. Mitchell notes. " Originally, the question was just really intriguing to me. I found that the higher level of antioxidants is enough to have a significant impact on health and nutrition, and it's definitely changed the way I think about my food."

Vitamin C in Oranges

Meanwhile, nutritional research on the vitamin C in oranges turns up similar results: organic oranges are richer in this antioxidant nutrient than conventionally grown oranges (Great Lakes Regional Meeting, American Chemical Society, 6/2/02).

The more common supermarket oranges are significantly larger than organically grown oranges, and they have a deeper orange color. Because of their larger size, "we were expecting twice as much vitamin C in the conventional oranges," says Theo Clark, PhD, chemistry professor at Truman State University in Kirksville, Missouri.

But when he isolated the chemicals in the oranges and further refined his search with nuclear magnetic resonance (NMR), spectroscopy demonstrated that organically grown oranges possess 30% more vitamin C than the conventionally grown fruits-even though they are only about half as large.

Dr. Clark isn't sure why organic oranges are richer in vitamin C, but he says, "...[W]e speculate that with conventional oranges, [farmers] use nitrogen fertilizers that cause an uptake of more water, so it sort of dilutes the orange. You get a great big orange but it is full of water and does not have as much nutritional value.

" However, we can only speculate. Other factors such as maturity, climate, processing factors, packaging and storage conditions require consideration." Along with analyzing oranges, Dr. Clark and his research team questioned about 70 people to measure their concept of the nutritional value of organic oranges. In this survey, 85% of the respondents thought that organic oranges have a higher nutritional content than conventionally grown fruit.

Dr. Clark's laboratory work shows that "they were right on." In Dr. Clark's view, these issues are important because consumers have a right to know the real nutritional content of organic produce, and the fact that analyses show that organic fruit has much more vitamin C validates the benefits of eating organic.

Defense Mechanism

Both plants and animals protect themselves from disease with many of the same chemicals. The natural substances that, in a farmer's field, defend vegetables from insects and microbes before they are harvested for your dinner go to work defending your body after you eat and digest them.

When you eat organic you bolster your health with more of these natural wonders. No wonder organic is becoming so popular!

--
Vitanet ®

Solaray - Ultimate Nutrition - Actipet Pet supplements - Action Labs - Sunny Greens - Thompson nutritional - Natural Sport - Veg Life Vegan Line - Premier One - NaturalMax - Kal

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Energy Cycles - Stress and lack of energy don't just frazzle your nerves

Date: June 12, 2005 02:09 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Energy Cycles - Stress and lack of energy don't just frazzle your nerves

Energy Cycles by Sylvia Whitefeather Energy Times, August 2, 2003

Feeling stressed out and exhausted from an overburdened schedule? Regenerating your personal energy necessitates defusing stress. Stress and lack of energy don't just frazzle your nerves; they can leave you depressed, anxious and vulnerable to a long list of health problems.

According to J. Douglas Bremner, MD, a psychiatrist at Emory University, Atlanta, when your brain overcharges on prolonged stress, your body pays a heavy, tiring price.

"If stress has effects on the brain and neurological function, then stress has effects on all parts of the body, including the heart, blood vessels, immune system and digestive system," says Dr. Bremner, author of Does Stress Damage the Brain? (Norton). "The long list of damaging effects can include heart disease, memory impairment, depression and even increased susceptibility to stroke and cancer."

A Good Night's Sleep

Although getting a good night's sleep is a basic part of lowering stress and boosting energy, many of us seem to be tossing and turning through an epidemic of insomnia. The fact that so many people appear to suffer from disturbed and unsatisfying sleep may signal not only a personal energy lack, but also a deeper health crisis developing on the horizon. Lack of sleep, along with stress, not only contributes to those lackluster afternoons of the blahs, but it can also derail your basic body rhythms, weaken your immune system and make you age quicker.

Researchers at the University of Chicago report that lack of sleep may deplete your get-up-and-go by upsetting basic metabolic functions and interfering with hormones. Pretty serious stuff: When people in this experiment cut back their sleep time to about four hours each night, their bodies behaved as if they were twenty years older and they started showing signs of developing diabetes. These effects Happened in only a week of missing sleep (The Lancet, October 23, 1999).

The drastically reduced sleep schedule slowed the thyroid gland, reducing the production and action of thyroid hormones. As a result, metabolism slowed and the non-sleepers developed that awful sluggish feeling too many of us know and hate.

Stress from lack of sleep also coaxed the adrenal glands into releasing extra amounts of cortisol, a stress hormone whose purpose is to force the body into providing short-lived energy boosts. But after a while the body flames out, its ability to cope with daily demands drained even further.

"We found that the metabolic and endocrine changes resulting from a significant sleep debt mimic many of the hallmarks of aging," says Eve Van Couter, PhD, professor of medicine at the University of Chicago and director of the study. "We suspect that chronic sleep loss may not only hasten the onset but could also increase the severity of age-related ailments such as diabetes, hypertension, obesity and memory loss."

And when are you are constantly short-changed of sleep, it builds up an accumulative effect. Particularly susceptible are busy parents, shift workers, menopausal women and college students.

One way to take back your energy from this metabolic madness is to get twelve hours of sleep a night for a week. But aside from hitting the snooze button a few hundred times, a possible antidote to this cortisol nightmare may be vitamin C.

Fight and Flight

The human body, which evolved before the advent of split-level houses and SUVs, was built to survive life-threatening, physical danger. When it encounters modern-day stress, such as traffic jams and credit card bills, it releases extra cortisol, heightening the body's immediate ability to run or fight. As a result of cortisol release, senses go on high alert, heart rate speeds up, blood flow to muscles increases, and the immune system mobilizes to deal with what it thinks is an imminent crisis.

However, unlike physical danger that rapidly resolves (either you get away from what's trying to harm you or it does you in), today's stress drags on and on (at least till the next exit on the expressway), and the cortisol in the body continues to circulate.

The long-range result of persistent cortisol is a drop in energy, rampant fatigue and lowered immunity. You feel constantly tired and you get sick more often. You may also gain weight.

But researchers at the University of Alabama at Huntsville have found that large doses of vitamin C "reduce...the levels of stress hormones in the blood and also reduce...other typical indicators of physical and emotional stress, such as loss in body weight, enlargement of the adrenal glands, and reduction in the size of the thymus gland and the spleen," according to P. Samuel Campbell, PhD (American Chemical Society, 1999). Dr. Campbell believes that our prehistoric ancestors probably consumed large amounts of vitamin C in a tropical diet rich in fruits. "If so, the physiological constitution we have inherited may require doses far larger than the present RDA (the amount the government recommends) to keep us healthy under varying environmental conditions, including stress."

Iron Out the Fatigue

If you are a premenopausal woman, a lack of iron may also be draining your body of energy. According to experts, as many as one of every five women who menstruate may suffer anemia caused by a lack of iron. This type of problem is also frequent in teenagers and during pregnancy. (But before you take iron supplements, talk to your health practitioner to make sure this is the source of your fatigue.)

"Women with heavy menstrual flow have the greatest risk (of anemia)," points out Susan Lark, MD, in Healing with Vitamins (Rodale). Dr. Lark recommends eating more iron-rich foods (like organic red meat) even if you are not anemic, since a mild iron deficiency can drag you down into the doldrums.

Vegetarians necessarily eat fewer iron-rich foods than do meat eaters. But if you take a vitamin C supplement when you consume such iron-rich vegetables as lima beans, pinto beans and spinach, your body can absorb more of the iron in these foods.

The Krebs Cycle: Keep the Wheel Turning

All of your cells make the energy that keeps you going. This process, a complicated chemical reaction called the Krebs cycle, transforms fatty acids and carbohydrates into ATP (adenosine triphosphate) for cellular energy. Mitochondria, small structures in each cell, are the centers of this energy production.

Energy production requires oxygen. The more oxygen available to the cells, the more energy is produced. Deep breathing and moderate exercise are simple, quick ways to oxygenate the body and boost energy. That is why walking, jogging and other physical activity wakes up your brain and restores pep.

If you've been looking for ways to feel more energetic, take a deep breath and go for a long walk before you sit down to your rejuvenating lima beans and vitamin C. And another thing...take a pass on those late-night TV shows. Sleep is more important.

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Vitanet ®

Solaray - Ultimate Nutrition - Actipet Pet supplements - Action Labs - Sunny Greens - Thompson nutritional - Natural Sport - Veg Life Vegan Line - Premier One - NaturalMax - Kal

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Herbs in Perspective

Date: June 10, 2005 10:25 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Herbs in Perspective

Herbs in Perspective by Phyllis D. Light, RH-AHG Energy Times, June 16, 2004

"I don't claim a cure...I just try to give people some ease," noted Tommie Bass, a traditional Southern herbalist whose life has been the topic of several books, including Mountain Medicine by Darryl Patton (Natural Reader Press) and Trying to Give Ease by John Crellin and Jane Philpott (Duke University Press). That philosophy reflects the perspective embraced by herbalists for eons.

The traditional use of herbs is incorporated into all cultures. Herbs were the first medicine and the origin of what we now call modern medicine. These plants have not been prescribed to conquer specific illnesses but instead nourish the body and aid in building overall health.

Traditional Knowledge

Observation, psychological need and human instinct form the foundation of traditional herbal knowledge and use. This knowledge has been passed down through generations based on practice and experience. The result: a depth of information about the safe and effective use of herbs that spans thousands of years.

The goal of a traditional herbalist is to bring the body into balance (homeostasis), prevent disease and support immune functioning. Unfortunately, any kind of therapeutic knowledge can be misused, and that has Happened with some herbs, causing some people to question herbal medicine's safety.

As more people turn to natural therapies, scientists have begun to perform evidence-based research into their safe and effective use. The good news is that much of this research has validated the effectiveness of herbs and supplements.

Echinacea to the Rescue

Do the sniffling sneezes that herald a cold have you reaching for your bottle of echinacea? If so, you are in good company. Echinacea (Echinacea spp) is one of the top-selling herbs.

The colorful American prairie plant was extremely popular during the early 1900s, until the use of modern antibiotics relegated it to the back shelf. But a resurgence of interest in herbs propelled echinacea back into the mainstream in the second half of the twentieth century. And this herb boasts an impressive body of research and has an excellent record of safety.

For instance, researchers at Virginia Commonwealth University School of Pharmacy have found echinacea to be effective in supporting the body's defenses against upper respiratory tract infections and for reducing the duration of discomforts that accompany the common cold (Pharmacotherapy 2000; 20(6):690-7).

Although studies have not confirmed its ability to prevent colds, echinacea is widely used by many folks for just that purpose. Researchers have found that echinacea's effectiveness may drop if you use it for eight straight weeks (Am J Health-Syst Pharm 1999; 56(2):121-2). So if you take it for a couple of months, take a couple of weeks off before using it again.

Flower Power

St. John's wort is another herb with ancient origins that has experienced a modern resurgence. Named after St. John the Baptist, St. John's wort (Hypericum perforatum) is generally in bright yellow bloom around St. John's Day (June 26). According to herbalist Michael Tierra, author of The Way of Herbs (Pocket Books), St. John's wort affects the liver and the nervous system. In 1984, the German Commission E, a recognized herbal authority, approved St. John's for depressive disorders, and in topical form for acute injuries and first-degree burns.

Modern research has reaffirmed the use of St. John's wort in the short-term treatment of mild to moderate depression (Cochrane Review Issue 2, 2004). It has also been found to be useful in premenstrual depression (Int J Psy Med 2003; 33(3):295-7). (Researchers have found that the herb may alter how the body processes some prescription medications, so check with your healthcare provider before using such medicines along with St. John's wort.)

King of Herbs

" Ginseng (Panax) received the lofty title, King of Herbs, due to its reputation as a tonic and its ability to stimulate the body into healing," notes herbalism writer Darryl Patton. This plant was once so popular in China that it was worth its weight in gold.

In fact, ginseng is the popular name for two different types of ginseng, American and Korean (Panax quinquefolium and P. ginseng). Both are considered adaptogens, or substances that help the body deal with stress more effectively. And modern research has found that ginseng can be used to improve overall energy and vitality, and to help the body deal more effectively with chronic stress (J Pharm Sci 2003 Dec: 93(4):458-64).

Researchers have found that ginseng helps boost the immune system (J Med Food 2004 Spring; 7(1):1-6). This ancient herb is also a powerful antioxidant that confers protection on the heart (Biochem Biophys Acta 2004 Feb 24; 1670(3):165-71). In other studies, ginseng has been found to reduce symptoms of menopause, improve endurance and lower blood sugar levels. To avoid overharvesting wild ginseng, most of the herb on the market is now grown on farms.

Ode to Ginkgo

Known as the Living Fossil, ginkgo is the oldest known plant in the world. A native of Asia, ginkgo (Ginkgo biloba) is now found in many US cities, where it has been planted as a quick-growing shade tree. Traditionally, ginkgo was used for disorders and diseases of the lungs and the kidneys, as a remedy for bronchitis and to improve circulation in older people.

Ginkgo contains substances that act as potent antioxidants by scavenging cell-damaging free radicals, and it is thought to help reduce the risk of disease. By opening capillaries, ginkgo increases circulation, and enables nutrients and oxygen to move around the body, especially to the extremities.

Indeed, recent research indicates that ginkgo may ease pain associated with arterial disease in the legs (Am J Med 2000; 108:276-81). Other studies support the use of ginkgo for acute stress (J Pharm Sci 2003 Dec; 93(4):458-64) and some cases of hearing loss (Acta Otolaryngol 2001; 121:579-84).

In a UCLA Neuropsychiatric Institute study on ginkgo, researchers found significant improvement in the verbal recall of people who had age-related memory problems. According to Dr. Linda Ercoli, lead author of the study, "Our findings suggest intriguing avenues for future study...with a larger sample to better measure and understand the impact of ginkgo on brain metabolism."

Tasty Ginger

Traditionally, fiery ginger (Zingiber officinale) has been used to aid digestion, reduce nausea, relieve gas, reduce symptoms of arthritis and strengthen the heart. Modern researchers have started to validate these traditional uses; ginger has reduced the nausea and vomiting of morning sickness in studies (Aust NZJ Obstet Gynaecol 2003 Apr; 4392:139-44).

Meanwhile, researchers at the University of Minnesota have applied for a patent on a substance found in ginger, believing it to have anticancer activity. According to Ann Bode, "Plants of the ginger family have been credited with therapeutic and preventive powers and have been reported to have anticancer activity."

Ginger can be found in natural food stores as fresh or dried root. It often appears in small amounts in herbal formulas as a carrier herb-one that helps move other herbs around the body.

The best medicine combines the health support of herbs with the scientific rigor of conventional medicine. And as scientists continue to search for new medicine from ancient remedies, we can enjoy the best of both perspectives.

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Vitanet ®

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COENZYME Q10 - Transforming food into energy

Date: June 01, 2005 11:06 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: COENZYME Q10 - Transforming food into energy

Coenzyme Q10

It’s 3:30 p.m. and you feel irritable; you can’t seem to concentrate. You were so busy you skipped lunch. At last you bite into the sandwich that you were ready for 3 hours ago. By the time you have eaten half of it, energy is starting to flow through you. What Happened? The answer to that question is both extremely complex and very simple. In essence, your body transformed the food into useable energy. CoQ10 is a crucial component of the primary energy generating cycle that takes place in each of the trillions of cells in our bodies. CoQ10 is essential for human life.

To transform that lunchtime sandwich into useable energy your body essentially has to burn it - just the way a car burns gasoline to drive its engine. This energy generating process takes place in structures called mitochondria - tiny power plants which are within every cell. Inside these energy generating stations, fats, sugars, and amino acids are transformed into ATP, an energy-rich molecule sometimes called the “energy currency” of the body.

Energy Generation Requires Nutrients

The body requires many nutrients in order to perform the complex biochemical processes that convert food into ATP “energy currency.” Some of these nutrients such as the B-vitamins are familiar to us. However, there are many other substances which are essential to this process. Coenzyme Q10 is one of these.

Functions of CoQ10

Several complex metabolic pathways are required in order for the body to transform that lunchtime sandwich into energy that you can feel and use. First glycolysis and the Krebs’ cycle break down large molecules of protein, carbohydrate and fat into smaller components. CoQ10 is a key enzyme in the Electron Transport Chain - the final stage in this extraordinary design. This pathway generates 90% of the ATP needed by the body from the food we eat. ATP provides the “energy currency” for the following crucial metabolic functions: 1) synthesis of cellular components including cholesterol and proteins (formed primarily by the liver), 2) nerve conduction (in the brain and peripheral nerves), and 3) energy for muscular contraction (of the heart and skeletal muscles). The Heart: The heart muscle (myocardium) consumes a tremendous amount of energy. Your heart beats over 100,000 times and pumps 1,000 gallons of blood each day! CoQ10 is necessary for the generation of the energy required by the heart. Numerous scientific studies have demonstrated that supplementation with this nutrient may support normal heart function. Its presence is necessary for cardiac performance during exercise as exemplified by criteria including: blood flow, oxygen utilization, contractility and exercise tolerance. In addition, CoQ10 may play a role in the regulation of blood pressure. The Gums: Since the 1970’s scientists have been researching the effects of CoQ10 on the health of the oral tissues. Although the mechanism of action is not known, research has established that CoQ10 has a profound ability to preserve and maintain the health of the gums. Antioxidant Properties: CoQ10 plays an additional vital role in our metabolism as a protector of lipids in cell membranes. Laboratory studies have also shown that CoQ10 is more efficient than vitamin E, beta carotene or lycopene in safeguarding LDL cholesterol from oxidation by peroxides. This process is important for maintaining the health of our blood vessels.

Energy Insurance

CoQ10 is needed in body tissues where energy production is critical, such as the liver, brain and muscles. Therefore we include CoQ10 in significant potencies in many of our premium formulas, such as Life Force Multiple™, Élan Vitàl™, Heart Science™, Liver Guard™, MenoBalance™, Higher Mind™, MegaMind™ and Wellness Multiple™. We also offer a combination of CoQ10 and Lipoic Acid (30 mg each), CoQ10 Sublingual (30 mg and 60 mg), 30 mg CoQ10 Softgels with Bioperine® and 30 mg CoQ10 NutraSpray™. Our single CoQ10 products are CoQ10 in 15 mg, 30 mg, 75 mg, 100 mg, and Ultra Potency 125 mg caps.

References
1) Folkers et al., BCACQ, Elsevier, 1977
2) Judy et al., BCACQ, Elsevier, 1984.
3) Kamikawa, T. et al., American Journal of Cardiology, Vol. 56, August 1, 1985, p. 247-250.
4) Nohara et al., Biomedical and Clinical Aspects of Coenzyme Q, Elsevier, 1984.
5) Packer, L., Oxidative Stress and Aging, Birkhauser Verlad, 1995.
6) Stocker, et al., Proceedings of the National Academy of Sciences, Vol. 88, pp 1646-1650, March 1991.
7) Tortora, G. Principles of Human Anatomy, 4th Ed., Harper & Row, New York, 1986, p. 301.
8) Wilkinson and Arnold, Biomedical and Clinical Aspects of Coenzyme Q, Elsevier, 1977.
9) Yamagami et al., Biomedical and Clinical Aspects of Coenzyme Q, Elsevier, 1977.

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Nattokinase: Food For Cardiovascular Health

Date: May 10, 2005 10:13 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Nattokinase: Food For Cardiovascular Health

Say it Ain't Soy!

Yes, but this soybean is different! What makes it different is simple. after hours of fermentation, the boiled soybean metamorphose to an ancient medicinal food called "Natto" pronounced "Nah'-Toe." Natto may just be the "perfect food," producing 18 valuable amino acids and an enxyme natokinase that may challenge the pharmaceutical industry's best "blood-clot busters." Natto, which has recently attracted attention throughout the world, is the third most popular type of fermented soybean in the japanese diet. Japan has the highest average longevity in the world, which may partly be attributed to a high consumption of natto.

When compared with ordinary soybeans, the natto produces more calories, protein, fiber, calium, potassium and vitamin B2. Its high protein and economical price in terms of protein per gram has earned it the sobriquet. "Hata-ke no niko," a meat of the field. This nickname appears well deserved, as in comparison with an equivalent amount of beef, natto has slighly less protein (16.5 grams to 21.2 grams),but contains more carbohydrates and fiber, and is also higher in calcium, phosphorous, iron and vitamin B2. Plus, it has nearly double the calcium and far more vitamin E to boot.

According to legend, the first person to originate traditional Japanese natto was the famous warrior Yoshiie Minamoto during the Heian era of Japanese history (794 - 1192 A.D.). The horse was extremely important to the Japanese samurai warrior of the period, and great care was given to provide suitable provisions for the horses when armies were on the move. Typically, boiled soybeans were cooled down, dried in teh sun and packed immediately in rice straw bags for transport with the army. If the army was on a rapid deployment, the boiled soybeans were packed hastely into the rice straw bags with out cooling or drying. The rice straw just Happened to contain a harmless and naturally occuring microorganism, Bacillus Subtilis that fermented the soybeans and producted natto with its characteristic sticky texture.

Initially, the soybeans were presumed to have spoiled until yashiie minamoto observed that his horses were "picky eaters" and demonstrated a preference for the "spoiled" Soybeans or natto. One day, Minamoto demonstrated tremendous courage and dipped his fingers into the seemingly rotten goo. To his astonishment, the fermented soybeans were not only edible but had a distinct umami flavor. Minamoto was responsible for introducing natto to northwestern Japan, where he ruled. To this day natto is especially popular in that region of Japan as a folk remedy for fatigue, beriberi, dysentery, heart and vascular deseases.

The most distinctive features of natto are the adheasive surrounding the soybeans and the strong flavor. The sticky material has been shown to consist of poly-g-glutamic Acid (D and L) and polysaccharides (Levan-form fructan), and the strong "cheese like" flavor is due to the presence of pyrazine. These features sometimes make it hard for some people, especially people from other countries, to accept natto; however, these are the main factors which give natto the outstanding properties. Natto, which has recently attracted attention throughout the world, is a familiar part of the Japanese diet.

Technical Aspects of Nattokinase:

Nattokinase produces a prolonged action in two ways: it prevents the formation of thrombi and it dissolves existing thrombus. Nattokinase orally administrated to twelve healthy adults indicated elevations in the breakdown products of the fibrin and the ability of the blood to break down fibrin called eugobulin fibrionlytic activity (EFA). These results suggest the ability of nattokinase to accelerate fibrinolysis in the blood for a prolonged period of time. FDP levels in the adults drastically increased 4 hours after the administration of the nattokinase, indicating that fibrin within the blood vessels is gradually being disolved with repeated intake of nattokinase. By measuring the EFA & FDP levels, the activity of nattokinase has been determined to last for 8 to 12 hours. An additional parameter for confirming the action of NATTOKINASE following oral administration is a rise in blood levels of tissue plasminogen activator (TPA) antigen, which indicates a release of TPA from the endothelial cells and/or the liver and the endogenous production of plasmin (The body's blood clotting buster).6,7

In 1995, researchers from Miyazki Medical College and Kurashiki Unerversity of science and arts in Japan studied the effects of nattokinase on the blood preasure in both animals and human subjects. In addition, the researchers confirmed the presence of inhibitors of angiotensin converting enzyme (ACE) within the test extract, which consisted of 80% ethanol extract of lyophilized viscous materials of natto. ACE causes blood vessels to narrow and blood pressure to rise - by inhibiting ACE; nattokinase has a lowering effect on blood pressure.1,2

The same natto extract was then tested on human volunteers with high blood pressure. Blood pressure levels were measured after 30 grams of lyophilized extract (Equivalent to 200 grams of natto food) was administered orally for 4 consecutive days. In 4 out of 5 volunteers, the systolic blood pressure (SBP) decreased on average from 173.8+- 20.5 mmHg to 154.8+-12.6 mmHg. Diastolic blood pressure (DBP) decreased on average from 101.0+- 11.3 mmHg to 91.2+- 6.6 mmHg. On average, this data representes a 10.9 percent drop in SBP and a 9.7 precent drop in DBP. 1,2,6

Disclaimer: The above artical is for informational purposes only and is not intended to diagnose or treat a particular illness. The reader is encouraged to seek the advice of a holistically competen t licensed professional health care provider. The information in this artical has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any desease.

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