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The Importance of Collagen for Your Health: Why You Should Care   
Date:
November 06, 2023 04:50 PM
The Importance of Collagen for Your Health: Why You Should Care
Have you ever heard about collagen? It might have been a buzzword in the beauty industry, but it's important to know that collagen is much more than just skin-deep. Collagen is actually a protein that plays a crucial role in providing structure, strength, and support to different parts of our bodies such as skin, bones, tendons, and ligaments. Lets explore the importance of collagen for your health, its different types and functions, the effects of collagen loss on the body, factors that affect collagen production, and how to boost collagen levels naturally.
Collagen production declines naturally with aging, leading to visible signs of aging like wrinkles, sagging skin, and brittle nails. However, several lifestyle factors also contribute to collagen loss like smoking, consuming sugary foods, and excessive sun exposure. Medical conditions like scleroderma and Ehlers-Danlos syndrome also lead to reduced collagen production.
Collagen loss can have various detrimental effects on the body. One of the most visible effects is on the skin where collagen loss leads to wrinkles, fine lines, sagging, and dryness. Collagen loss also affects joints, resulting in pain and stiffness. Since collagen is crucial to maintaining bone structure, a decrease in collagen levels weakens the bones and muscles, causing osteoporosis. Collagen is important for the digestive tract lining, so when the body lacks sufficient collagen, people could experience digestive issues. Lifestyle Habits Leading to Collagen Loss: Several lifestyle habits exacerbate the natural decline in collagen production, thereby speeding up the aging process and negatively affecting overall health. First among these is smoking. The chemicals present in cigarettes damage collagen and elastin, causing premature skin aging with characteristic wrinkles and sagging. Not only does smoking impact the skin, but it also affects collagen-rich organs and tissues, leading to various health problems. Next is the consumption of excessive sugar and refined carbohydrates. A high-sugar diet interferes with collagen's ability to repair itself, leading to inflammation and collagen cross-linking that results in skin aging and joint discomfort. Refined carbohydrates spike blood sugar levels, encouraging the same damaging process. Last but not least, ultraviolet (UV) light exposure, particularly from the sun, can also lead to significant collagen loss. UV light increases collagen breakdown by activating enzymes called matrix metalloproteinases that degrade collagen and elastin. This exposure results in photoaging of the skin, characterized by deep wrinkles, leathery texture, and pigmentation changes. Therefore, it's crucial to protect your skin from the sun by wearing SPF every day, even on cloudy days.
Fortunately, several natural ways can help boost collagen levels in your body. Maintaining a balanced diet rich in vitamins and minerals such as vitamin C, zinc, copper, and iron is key to boosting collagen levels. Vitamin C is vital in the production of collagen, which makes it an essential nutrient for the body. Excessive sun exposure and smoking lead to the accumulation of free radicals that damage collagen, so avoiding these is key. In addition, the topical use of skincare products like sunscreen and moisturizers protects and nourishes collagen and helps maintain healthy skin. Exercise such as weight training and yoga can help stimulate collagen synthesis, ensuring youthful-looking skin, healthy joints, and strong bones. Common types of collagen!
Collagen is an essential protein that is vital for overall health and well-being. It provides support and structure to different body parts, ensuring their optimum functionality. The decline in collagen production is an inevitable part of aging, but several natural ways can help boost its levels. Maintaining a balanced diet, avoiding habits that damage collagen, and practicing regular exercise can help maintain healthy collagen levels. It's crucial to remember that relying solely on supplements may not necessarily boost collagen levels, so it's best to consult your healthcare provider before taking them. So, go ahead and adopt healthy habits to maintain healthy levels of this crucial protein. Your body will thank you for it!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6588) The Many Health Benefits of Copper Glycinate 
Date:
October 25, 2022 04:49 PM
You may not realize it, but copper is essential for many different bodily functions. This trace mineral is involved in energy production, iron metabolism, connective tissue syntheses, and neurotransmitter production. Copper is also critical for bone health, cardiovascular health, lipid metabolism, neurological health, skin health, and free radical protection. Keep reading to learn more about the many health benefits of copper. Copper and Energy Production One of the most important roles that copper plays in the body is in energy production. Copper is a key component of mitochondria, which are known as the "powerhouses of the cell." The mitochondria produce ATP (adenosine triphosphate), which is the energy currency of the cell. Therefore, without adequate copper levels, your cells would not be able to produce enough ATP for optimal function. Copper and Iron Metabolism Another important role of copper is in iron metabolism. Copper is necessary for the absorption and utilization of iron in the body. Iron is a key component of hemoglobin, which carries oxygen around in the blood. Therefore, without adequate copper levels, your body would not be able to properly utilize iron, leading to anemia or other problems. Copper and Connective Tissue Synthesis Copper is also necessary for the synthesis of collagen and elastin, two proteins that make up connective tissue. Connective tissue includes things like skin, tendons, ligaments, and cartilage. Therefore, copper is necessary for healthy skin as well as strong tendons and ligaments. As you can see, copper plays many vital roles in the body. If you are deficient in copper, you may experience fatigue, anemia, weak bones or connective tissue, problems with lipid metabolism or neurological function, or poor skin health. To ensure that you are getting enough copper in your diet, eat foods like liver, oysters, lobster, dark chocolate, avocados, almonds, mushrooms ,or leafy green vegetables. You can also take a copper supplement if needed.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6526) Collagen for Healthy Joints, Bones and Skin
Date:
October 03, 2022 03:04 PM
Collagen is a protein that is found in abundance in mammals. It makes up about 30% of the body's protein and is known for its roles in bone, joint and skin health. Studies have shown that hydrolyzed collagen can help to support strong bones, healthy joints and smooth, hydrated skin.* Lets take a closer look at the benefits of collagen peptides from types 1 and 3 bovine collagen. As we age, our bodies produce less collagen. This decrease in collagen production can lead to a number of age-related issues such as wrinkles, joint pain and weak bones. Supplementing with collagen peptides can help to offset the decline in natural collagen production.* Collagen peptides are easily absorbed by the body and have been shown to promote joint health, bone density and skin elasticity.* There are many different types of collagen, but types 1 and 3 bovine collagen are most commonly used for supplements. Type 1 collagen is particularly good for skin health, while type 3 collagen is best for joint health. Both types of collagen are found in our bones, tendons, ligaments and skin. Hydrolyzed collagen from types 1 and 3 bovine sources provides the most benefit for overall bone, joint and skin health.* Collagen peptides from types 1 and 3 bovine sources are well-known for their roles in supporting bone, joint and skin health. Supplementing with hydrolyzed collagen can help to offset the decline in natural collagen production that occurs as we age.* Collagen peptides are easily absorbed by the body and have been shown to promote joint health, bone density and skin elasticity.* If you're looking for a supplement to support overall bone, joint and skin health, consider hydrolyzed collagen from types 1 and 3 bovine sources.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6480) Did You Know That Coconuts Are Healthy? If Not, Then Check This Out!
Date:
December 15, 2016 02:59 PM
Coconut meat is the rich white lining that is contained within the shell of a coconut. Coconut meat can be juicy and tender, or slightly thick and crunchy, to tough and fibrous depending on how long the kernel has been stored. Though coconut only grows in tropical regions of the world, it is now widely available in the American consumer market. And this is a fortunate thing as eating food products derived from coconut like coconut oil and coconut meat on a regular basis has profound positive effects to your overall health. Key Takeaways:
"Coconut also contains short-chain fatty acids and medium-chain fatty acids that have amazing benefits." Reference:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3652) Bursitis and tendinitis
Date:
December 12, 2016 06:59 AM
Do you work a labor intensive job? Always throwing or lifting heavy objects? Well if this is the case you may be more inclined to suffer from Bursitis and tendinitis, two diseases that affect the joint and ligaments. A doctor may be able to tell you if your pain is one of these conditions. Key Takeaways:
"The most important thing is to get into condition gradually and to ease into vigorous exercise gently." Reference:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3624) Improving your posture could help reduce muscle pain, joint pain and headaches
Date:
December 11, 2016 06:59 AM
When it comes to posture, your mother did know best. Her reminders to stand up straight and stop slouching were good advice. Your spine is strong and stable when you practice healthy posture. But when you slouch or stoop, your muscles and ligaments strain to keep you balanced — which can lead to back pain, headaches and other problems. Key Takeaways:
"If you often find yourself suffering from neck and back pain, you may have blamed your pillow or even your bed for the discomfort, but the problem might have nothing to do with your furniture and everything to do with the way you carry yourself." Reference: //www.naturalnews.com/056176_posture_pain_prevention_headaches.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3617) How Does a Collagen Supplement Help With Joint Pain and Also To The Skin?
Date:
July 27, 2015 06:45 AM
Collagen is said to be the most abundant available protein in the body of humans. It forms fibers which are found in ligaments, cartilages, tendons and bones. It's a vital kind of protein in all mammals and it's about 30% the total amount of proteins in the body. Collagen fibers are responsible to ensure flexibility of the skeletal system. As ages increase as per from 25 years, collagen level decreases. This is the main reason why elderly people develop wrinkles which is a result of elasticity loss of the skin due to the decreased collagen level. Brittling of the nails, hair loss, stiffening of joints are also things that happen due to decreased collagen level. This makes collagen supplement very essential because it can prevent all that. Clinical related studies done over many years have shown clearly that collagen supplements is not only effective in stimulating the natural production of new collagen but also it does replace any missing collagen. Supplementation of collagen helps in maintaining and improving the health of the skin, arthritis, nails and hair and also relieving the joint pains. The collagen supplements mainly for joint pain and also arthritis are available in two major types: type II collagen and type I collagen. The type I collagen mainly helps to rebuild the cartilage in the joints. These will result in reduction of stiffness and pain which is majorly as a result of breakdown of these vital tissues. Presence of adequate cartilage will ensure improvements in joint movements. When it comes to type II collagen, it is actually the main protein which is lost during the aging process. People tend to prefer this supplement since it the collagen itself. Collagen is very important in joint health, although many people have thought of it as a wrinkle kind of treatment. Specific types of arthritis may cause the cartilage in joints loose elasticity and after sometime cause wearing of in areas that moves the most. This area are such as ankles, knees and wrists. With no collagen, there is not enough cartilage. Therefore, ligaments and tendons stretch to fill any missing cartilage which cause tremendous pain. You can always find collagen at any local or internet store, and be sure you will reap its benefits.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3183) Does Camu Camu Fruit Have Healing Properties?
Date:
April 02, 2014 09:10 PM
What is a camu camu Inside a rainforest you will discover these types of bushes of which increase within the Rain forest avalanche. The actual fruit obtain from canoes as well as watercraft after that eaten fresh, dried or made into centred fruit juice. Some other part of these berries may be used as well as ingested in various means. Camu Camu contents and benefits The actual Camu Camu fruit boosts the manufacturing involving serotonin, the hormone that makes your senses beneficial. The higher level of vitamin G involving any vegetable that helps to improve your entire metabolic rate. There may be exploration evidence of which implies that the fruit features anti-oxidative as well as anti-inflammatory. In addition, it functions as anti-aging method. The actual large antioxidant part of this Camu Camu berry makes a strong compound with healthier skin care solutions. You will discover scientific studies that it has an anti cancer properties. The actual Camu will be adapted straight into makeup as well as healthy skin care because hugely rejuvenative talents. On the list of crucial ingredients for you to locate a wholesome life is having the necessary every day level of Nutritional G. Nutritional G is surely an ascorbic p, is normal water-soluble as well as has a critical role inside our each day eating plan. Contrary to almost all mammals, people are not able to by natural means develop Nutritional G consequently, we should acquire the idea inside our eating plan. The actual role of which Nutritional G does eat the body is always to synthesize collagen, and that is a significant structural component of tendons, ligaments, arteries and, as well as navicular bone. Nutritional G is significant since it helps to merge this ingredient component of this neurotransmitter, norepinphrine. Neurotransmitters usually are crucial for you to mind perform. Among other items additionally, it is related to help with our blood cholesterol levels plus the regularity involving gall stones. The word antioxidant goes in conjunction having Nutritional G. Antioxidants are critical within defending one's body coming from harmful free of charge radicals. The actual deficit involving Nutritional G in every day eating plan have been recognized for countless years for you to result in this generally dangerous illness involving scurvy. Any insufficient Nutritional G is even related to heart conditions. Nutritional G deficit in addition has been assigned to, cerebrovascular event, most cancers, cataracts, and in many cases guide toxicity. Final thoughts, include the ability from the Camu Camu fresh fruits antioxidant potency for you to fight free of charge radicals as well as re-balance these physiques systems. Combined with the berries, Camu Camu is easily transforming into a recognized super fruit, which includes many reasons as well as prices regarding man well being.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3086) What Are the Health Benefits Of Collagen Tablets?
Date:
April 10, 2012 06:57 AM
Collagen Collagen is one of the most important components involved in the formation of your body's ligaments, tendons, cartilage and muscles. As you get older, your body's ability to manufacture the required amount of collagen becomes lesser. Collagen tablets covers up for it by helping maintain the repair process. These tablets also have different benefits that you should consider and these benefits re given below: Improves blood circulation: this happens because collagen tablets improve the elasticity of blood vessels, making them stronger and this improved blood flow. It enhances healing of injuries: when our bodies cannot provide sufficient nutrients required to repair the body tissues, these tablets compensate for the loss. The structure of the bones, cartilages and other parts are also strengthened by this. It encourages the regeneration of muscle mass making recovery after sport related injuries faster. Keep Arthritis pains at bay: the disease associated with joint inflammation and painful mobility around the areas is referred to as Arthritis. Collagen tablets work at reducing this pain making movement around the joints more comfortable. Reduces the appearance of cellulite: when fatty tissues find way to the upper layers of the skin, dimples often occur. This is referred to as Cellulite. These tablets reduce this occurrence by rebuilding the destroyed fibres that allow cellulite to appear. Helps in reducing wrinkles: when our bodies no longer produce collagen, certain lines form on the places that move most, like our foreheads and joints. This is referred to as wrinkles. The tablets work by increasing the suppleness of the skin. Improves the hair structure: these tablets fight free radicals which often affect the texture and growth of our hair. Replacing this component in the shaft of your hair will give your hair better appearance. It is advisable to start taking these tablets from as early as thirty years as this will prevent the onset of the above conditions. It also makes your skin look younger by preventing wrinkles. One should use these tablets because its absorption occurs naturally through the blood stream, making it possible for your body to decide its destination. If you are an athlete, this is just the thing for you as it facilitates the healing of wounds making it possible for you to be back on the field within a short time. The tablets can help soften your stiff joints if you find it hard to exercise because of that. If acne is your problem, then you won't have to worry, because this drug works with your skin's keratin to produce the best results ever. It is also said to have an effect in weight loss. One thing that you should note is that collagen tablet works best on an empty stomach, so for the best results, take it early in the morning or before meals. These tablets are cheap and easy to find. They contribute greatly to your health and overall appearance. Now that you know, take that short trip to the nearest chemist and take control of your future life! Collagen tablets are a good way to start.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2631) GLUCOSAMINE: Origin and Action of Mechanism
Date:
February 06, 2012 01:08 PM
Glucosamine is an amino sugar made from glucose and amino acid glutamine. It is a monosaccharide that is found naturally in healthy joints, cartilages, ligaments, muscles and tendons. It helps in the formation and repair of cartilage and other body tissues. Glucosamine is available in the form of dietary supplements, cosmetics and sports drinks. Let us find out about the history of glucosamine and its role in repair and treatment of joint disorders. HISTORY of GLUCOSAMINE: Glucosamine was first discovered in 1876 by Dr. Georg Ledderhose. It was prepared by hydrolysis of chitin with Hydrochloric acid. Later on it was developed in sulphate blend. Since then, it has been studied multiple times and in multiple ways to find out its potent health benefits. It has been used clinically in Europe since 1960s. In 1971, researcher K. Karzel glucosamine HCl stimulated the production of glycosaminoglycan layer, which helps in protecting cartilages, ligaments and tendons from normal wear and tear. It became popular in United States in the mid 1990s with the publication of popular bestsellers such as 'The Arthritis Cure' by Jason Theodosakis. Now it has become the most popular selling dietary supplement with sales of $200 million per year. Glucosamine is naturally found in the body and can be synthetically made from the natural sources of chitin that is found in sea creatures such as shells of shell fish, bones and bone marrow. How does Glucosamine Works in reducing Joint pain? Our body's ability to produce glucosamine decreases as we age. Hence after any kind of injury cartilage, spinal discs and joints, the body may not be able to heal optimally. Aging and glucosamine depletion in the body leads to joint degradation. However, glucosamine supplementation can support cartilage and CT-integrity limiting degeneration. Glucosamine supplements do not work like NSAIDS, which are known to have anti-inflammatory and analgesic effects on the body. The exact mechanism of significant analgesic effect of glucosamine supplements is unknown but according to various studies, glucosamine has no effect on cyclooxygenase system. Studies have shown that glucosamine stimulates synthesis of proteoglycan in a dose dependent manner. It helps in stimulating the production of cartilaginous matrix, hence counteracting the degrading loss of cartilage in case of arthritis or injury. Several important studies demonstrate the role of glucosamine in stabilizing cell membranes, inhibit lysosomal enzymes and reduce the generation of oxygen free radicals by macrophages. It may inhibit interleukin 1 induced nitric oxide activity that leads to chondriotic cell death. Hence it increases aggrecanase activity that helps in preservation of proteoglycan. Glucosamine along with Chondroitin sulphate stimulates synthesis of cartilage precursors as well as synovial fluid. They also limit the degradation of existing cartilage in any loss of joint integrity. This non rapid acting drug has many beneficial effects in reducing the symptoms of osteoarthritis. It is a powerful joint repairing supplement that rebuilds joint cartilage. Glucosamine supplements have been thoroughly evaluated to find out any potential side-effects. However, it has been proved that it does not have any of the side-effects of NSAIDS, surgery or opiods.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2555) What are the Essential Amino Acids we must get from our Diet to Survive?
Date:
August 17, 2011 12:13 PM
Amino acids or the building blocks of protein are very important in overall functioning of the body. Proteins, to mention, are responsible for the build up of most of our body parts specifically our muscles, ligaments, tendons, organs, tissues, glands, nails and hair. Moreover, the repair and preservation of those parts still rely on proteins. Amino acids can be of two different forms which are the non-essential and essential. On this selection, we will be focusing more on the latter. Essential amino acids are those which cannot be produced by the body therefore it has to be supplied through our diet. This category of amino acids includes tryptophan, lysine, methionine, valine, leucine, isoleucine, threonine and phenylalanine. Tryptophan, which is a precursor to serotonin and melatonin, can be acquired from peanuts, meat, turkey, fish, milk, dried dates, cottage cheese, banana, oats and chocolates. A deficiency of this can bring up serious neurological problems, depression, anxiety and sleeping difficulties. Another essential amino acid is methionine. The production of sulfur and other compound needed for a healthy growth and metabolism depends on the presence of this amino acid. Fish, whole grains and dairy are its sources. Lysine, which is effective in the treatment and prevention of herpes, is present in soybeans, green beans, lentils, spinach and amaranth. Low levels of lysine can also compromise the levels of niacin and this leads to pellagra. Tissue healing, muscle metabolism and keeping the equilibrium of nitrogen levels in our body are the functions of valine. It has proven to be efficient in the treatment of liver and gallbladder disorders. Deficiencies that results from drug addiction are can also be reversed by this amino acid. Its sources are peanuts, soy proteins, dietary products, grains, meat and mushrooms. Leucine can be obtained from chicken, fish, cottage cheese, lentils, peanuts and sesame seeds. It functions in muscle protein build up and is the main medium in tissue building process. Inability to acquire such makes a person prone to protein wasting since leucine, together with valine and isoleucine, serves as energy and protein reservoirs. In boosting energy levels, blood sugar regulation, muscle build - up and repair as well as hemoglobin development, isoleucine has shown its relevance. Its dietary sources are fish, poultry, beef, dairy, eggs, lentils, seeds, soy, almonds and wheat. Isoleucine deficiencies may result into neurological disturbances such as confusion, depression, irritability, fatigue, headache and dizziness. Threonine is significant in synthesis of antibodies. Beans, nuts, seeds, dairy, poultry, eggs and beef are rich in threonine. A low level of this amino acid causes disorders of the skin and weakness. Adrenaline and noradrenalin which are stimulates the central and peripheral nervous system requires phenylalanine to perform their function. Phenylalanine can be acquired from peanuts, seeds, almonds, lima beans and dairy. Liver damage, weakness, skin lesions, lethargy and slowed growth are results of its deficiencies. In summary, our body needs networks of essential amino acids for its proper functioning. Eating healthy foods and living a healthy lifestyle is the secret towards maintaining your optimum general health.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2396) Can Dietary Collagen Help the Skin and Joint Tissue?
Date:
June 30, 2011 10:45 AM
Collagen and Your Health
Collagen is the most common form of protein in humans and other mammals. It is a major constituent of the extracellular matrix that provides structural support to animal cells from the outside. It displays great tensile properties, which is responsible for the strength and elasticity of the skin. Since it is a component of fibrous tissue, it is also found in ligaments and cartilages that make up joint tissue. Dietary collagen has long been postulated to contribute to the biochemical composition of cells present in the skin and joints. Proponents of collagen supplements believe that dietary collagen is assimilated into the extracellular matrix and fibrous tissue. The scientific community has been doubtful about the efficacy of topical applications of collagen, but oral supplements have been promising in clinical trials. Molecular collagen is composed of polymers of amino acids linked by peptide bands, which are too big at the cellular level to get absorbed through skin. On the other hand, intestinal absorption of dietary collagen remains a matter of controversy. That being said, nutraceutical companies have developed formulations of supplements that facilitate the best possible absorption rates and better bioavailability. Tough bundles of collagen fibers comprise several polypeptide chains of fibrous structural proteins. All fibrous tissues have cells and extracellular matrix in between. High concentrations of collagen found in cartilages, ligaments, tendons, fascia, and even bones give these fibrous tissues tensile strength, the reason why the joints are capable of bearing a certain level of longitudinal stress without tearing apart.
Structural proteins make up the outer layer of the human skin and its appendages, such as the scalp, hair, and nails. The most important of these proteins are collagen, keratin, and elastin. Collagen fibers are responsible for the tensile properties of the skin. Keratin provides strength whereas elastin exerts an elastic effect. Collagen fibers affect the process of healing and its degradation leads to wrinkles. Oral route of administration is believed to produce the health benefits linked to dietary collagen. While researchers have ruled out the health claims tied to collagen creams and lotions, they have reported encouraging results about dietary collagen. In fact, collagen supplements utilized in the management of rheumatoid arthritis and treatment of skin disorders have produced significantly positive outcomes. One clinical trial that involved more than 200 participants diagnosed with rheumatoid arthritis point to the medicinal potential of collagen as an adjunct treatment for rheumatism and osteoarthritis. There was a noticeable decrease in joint pain, morning stiffness, and restrained mobility, which were noted as statistically significant. For this reason, supplementation of collagen has attracted more research. Dietary collagen is now becoming increasingly visible in the nutraceutical industry in that sales have increased in the past few years. It has become the subject of numerous studies well underway, and as such developments in collagen supplementation are expected to produce formulations specialized for higher bioavailability. The good news is dietary collagen has not been linked to any adverse effects. Get some collagen today and feel the difference it can make in your diet!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2354) How Does Cherry Fruit Extract Help with Gout?
Date:
March 07, 2011 04:39 PM
Cherry fruit extracts contain the micronutrients and phytochemicals found in cherries. They are available as supplements widely touted to display antioxidant and anti-inflammatory properties. Cherries, the fruits, are in fact very high in anthocyanins, which have a long association with the prevention of inflammation, even including the type that results in most known cardiovascular diseases. Also, research on anthocyanins in connection with its chemopreventative potential has yielded the most reliable public data. Individuals suffering from gout will definitely benefit from cherry fruit extracts as supported by an abundance of reports and anecdotal evidence concerning its efficacy.
Stabilizes Metabolism of Purine NucleotidesThe development of gout is greatly attributable to an anomaly in the metabolism processes involving purine nucleotides. A class of organic compounds classified as purines is necessary for life and present in many chemical reactions. They are a major component of ATP, the primary energy of cells, and several nucleotide bases of DNA and RNA are purines. The problem lies in its final metabolic product, uric acid, which at high levels condense into urate crystals that are deposited in tendons and ligaments, as is the case with gout and tophus. Cherry fruit extracts bring about twofold effects. First, they stabilize purine metabolites, notably uric acid, and, second, they facilitate the effective excretion of uric acid. If you consume a lot of foods high in purines such as animal products, especially beef, pork, and seafood, taking cherry fruit extracts will make sure that the uric acid they produce gets out of your system. Affects Releases of Inflammatory Mediators While high levels of uric acid is the causation of gout attacks, the painful inflammation that ensues is triggered by an entirely different group of endogenous compounds in the employ of the immune system. Eicosanoids have long been identified to precipitate pain not only during gout attacks, but in all inflammatory responses of the human body. These compounds are released locally by the cells around the joints containing urate deposits in an attempt to fight off the degenerative effects of uric acid on the surrounding tissues. They deal with the joints the same way they get rid of pathogens during infections, bringing on the redness, swelling, and pain characteristic of gout. A group of bioflavonoids called anthocyanins that are known to interfere with the releases of eicosanoids are abundant in cherries, and intake of cherry fruit extracts deliver these flavonoids into the region of pain. Normalizes Acidic Digestive Environments Cherries belong to the group of foods that are alkaline forming. With gout thriving in an acidic setting, it is just prudent to carefully reassess your diet and cut down on foods high in purines. Not surprisingly, your doctor may tell you to minimize consumptions of meat products especially if you suffer from recurrent gout attacks. Cherry fruit extracts rebalances the pH level of your gastrointestinal tract, and supplementation will keep your body in an alkaline state in the long run, protecting you not only against gout but also against the aging process.
If you suffer from gout or other uric acid buildup disease, give cherry fruit extract a try today!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2248) Glucosamine and Joing Pain
Date:
April 05, 2010 04:34 PM
A decline in the amount of glucosamine production occurs along with the normal aging process. This compound is involved in the natural cushioning of the joints, which means that damage and pain can result from a lack of glucosamine. When the natural cushion is gone, the bone and cartilage may rest against each other, which in turn causes deterioration. Not only can this occur in the joints, but it can also occur in the spinal column.
Glucosamine sulfate has proven to be an effective treatment for osteoarthritis. In fact, some have found that this treatment works better than conventional therapies. This is because it does more than just mask the pain. Rather, it actually aids in rebuilding and stimulating joint repair. Also, glucosamine Scientific evidence shows that glucosamine metabolism is altered when osteoarthritis is present within the body. It has been found that glucosamine supplements provide an effective treatment for this condition. Studies, up to this point, have found substantial improvement in those individuals who are treated with glucosamine. There is little risk, if any, involved in the use of glucosamine for the treatment of osteoarthritis. Studies have shown that this compound is very safe and does not possess any known precautions or risks. One study even determined that glucosamine sulfate has the ability to help stimulate the defense mechanisms that are present within the stomach lining. Pain and anti-inflammatory medications, on the other hand, often cause stomach problems such as ulcers.
Glucosamine sulfate has been shown to be an essential part in treating osteoarthritis. Scientific results showed significant improvement in swelling, pain, and degeneration of joints with the use of glucosamine sulfate. Not only is this compound important for reducing the symptoms that are involved with osteoarthritis, but the supplement has been found to actually reverse the degenerative process and induce healing. This compound should be considered to be a form of treatment for osteoarthritis.
It should be noted that when taking this, or any other supplement, one should consult their health care provider before beginning any type of supplementation. Glucosamine may not be recommended in some situations. Do not take glucosamine without first talking to your doctor if you are pregnant or could become pregnant. Similarly, be sure to consult your doctor first if you are breast feeding a baby. For more information on the many beneficial effects provided by glucosamine, please feel free to contact a representative from your local health food store.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2135) Fight Cold Sores And Build Collagen
Date:
April 29, 2009 10:18 AM
Lysine is an essential alpha-amino acid, in that it cannot be biosynthesized by the human body, and therefore must be taken in your diet or as a supplement. It is synthesized in plants from aspartic acid, and metabolized in the body to produce acetyl-Coenzyme A (acetyl-CoA). Before discussing its action on herpes, we shall first have look at how Lysine helps with the formation of collagen. Collagen is a protein that is produced in the body from lysine and proline, another amino acid. In fact the primary role of amino acids in your diet is as building blocks to form the much larger protein molecules. Collagen is fibrous, and forms the connective tissue such as cartilage, ligaments, tendons, blood vessels and skin. Even the external parts of the ears. It literally holds our skeletons together, and wraps the whole body up in skin, so if we had no collagen we would literally fall apart! Collagen is also used by body cells to form the matrix that the body cells use to attach to each other and is one of the most important types of tissue in your body. It is so ubiquitous that over 30% of the protein contained in your body is collagen, and it is designed for its structural strength as opposed to its ability to take part in chemical reactions as other proteins are. Lysine and Vitamin C are essential for the maintenance and formation of collagen. There is not a lot of lysine in collagen - only about 4%, but it is very active in the cross-linking that forms the fibrils of collagen. Fibrils are the hair-like structures formed in a triple helix arrangement by three protein chains twisting round one another. The fibrils are bundled together in a straight line that has amazing tensile strength. The tensile strength of collagen is, weight for weight, stronger than steel! In order for lysine to take part in this process effectively, some molecules have to be hydroxylated and others oxidized, forming aldehydes. Things can go wrong here, and deficiencies in the metabolic process can lead to some heritable conditions, or diseases of connective tissue. Among these are lathyrism, Cutis-Laxa and the Menkes kinky hair syndrome. However, lysine is a very versatile amino acid, and not only is it necessary for the biosynthesis of all proteins, but is also heavily involved in the production of enzymes, hormones and antibodies. It is an important component of the calcium absorption process, and also, as previously stated, can be used in the treatment of herpes simplex. This form of herpes is known commonly as 'cold sores', and is a result of the activity of the herpes virus. Viruses do not reproduce in order to ensure the 'continuation of the species', but replicate. In order to achieve this it requires the help of another amino acid, arginine. This is a common amino acid whose sources include grains, seeds, peanuts, raisins and chocolate. Lysine and arginine competes for the absorption and entry of tissue cells, and reduces the strength of arginine, so preventing the growth of herpes. For this reason a supplement of lysine can be used to reduce the effects of the herpes simplex virus, and lessen the symptoms of the cold sore. However, it is not only cold sores but other forms of herpes that lysine can help to relieve. Herpes zoster is a virus that causes shingles. This virus is generated by the reactivation of the dormant varicella-zoster virus left in the tissues after chickenpox. It is a recurrent condition, and lycine can help to reduce recurrences as well as its severity. Apart from being an effective defense against herpes, and forming collagen, the amino acid imparts several other benefits to the human body. Among these is osteoporosis. L-lysine is involved in calcium absorption in the intestine, and also helps to reduce the loss of calcium in the urine. In osteoporosis we have to try to make every calcium molecule ingested in the diet to be incorporated in the bone structure. L-arginine can work with lysine to enhance the activity of the body cells that produce bone. Canker sores are often mistaken for cold sores, but they are actually quite different. They are small sores inside the mouth, and appear in the form of very painful ulcers. The cause is unknown, but is believed to be a virus, and lysine appears to help the condition. Although there have been no proper clinical tests carried out on its use as a remedy for canker sores, lysine appears to help, and a supplement is recommended as a treatment by many doctors. It will do no harm, and anybody suffering from these tiny but painful sores will try anything. Although lysine deficiency is rare, it can occur, particularly amongst those observing a vegetarian macrobiotic diet, and also in athletes who frequently undertake vigorous exercise, especially with too little recovery time. The effects of a deficiency are fatigue, nausea, appetite loss, anemia, slow growth and kidney stones. The latter is likely due to a failure to absorb calcium, that L-lysine promotes, and the formation of calcium oxalate and other insoluble salts in the kidney. Dietary sources include beans and other legumes, and although it should be available in cereals, baked foods and doughnuts, for example, the carmelization of sugars binds the lysine to the sugar, and so reducing its bioavailability. However, you can also get it in cheese, eggs, tofu and red meats. If you are taking an arginine supplement, you should consult your physician prior to taking lysine. The reason for this is that lysine and arginine share biochemical pathways, and arginine can reduce the effective concentration of lysine. However, it has not been tested by the FDA, nor approved, and any use is at your own risk. This risk appears to be very small, although its manufacture is not regulated. However, do not let this bother you: the proof of the pudding is in the eating as they say. Many have found lysine to be effective with collagen or herpes problems, and a supplement of between 3,000 and 9,000 mg per day is recommended for those with herpes viral infections. It is not recommended for children under two years old. Lysine is available at your local or internet health food store at discount prices. Look for name brands to ensure purity and quality of the product you purchase. Another Great Cold Sore Remedy is Red Marine Algae!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1998) Hyaluronic Acid can help Restore Joint Function
Date:
December 01, 2008 10:03 AM
Hyaluronic acid, also known as hyaluronan, is one of the main components of the extracellular matrix of connective tissue and joints, and is one of the main chemicals contained in the synovial fluid that lubricates your joints. Before we discuss how it can be used to help restore the function of damaged joints, let's have a look at what causes joint pain, and why joints can break down long before their time. You might have heard that arthritis is an inflammatory condition, or that it is due to the immune system. This is true to an extent, and rheumatoid arthritis is an immune system problem, although osteoarthritis is a different problem altogether. Arthritis is not the only cause of joint pain of course, but is by far the most common cause. As already inferred, there are two forms of arthritis, each with a different basic cause. Osteoarthritis is the most common form of joint disease, and is largely due to wear and tear, injury or can be hereditary. However it is usually initiated by damage, the joint surface becomes roughened and the bone around the damaged area gets thicker to compensate. A joint is where two bones meet, and not all joints move. You have the fixed joints in your skull, for example, and those between the ribs and the spine. However, arthritis generally affects the joints associated with movement, mainly the knees, hips, fingers, toes and elbows. The ends of the bones are covered with a thin layer of cartilage, which can absorb shocks and both cushion the joint and allow the ends of the bones to move smoothly over each other. Round each joint is a membrane known as the synovium that is filled with the thick synovial fluid, which lubricates the cartilage. The bone ligaments hold them close to the joint, and prevent them moving too much and dislocating. Finally, the joint is completed by the tendons that attach the muscles to the bones they control. Osteoarthritis causes a joint to deteriorate: the cartilage becomes rougher and wears, and the bone beneath the cartilage gets thicker. At the edge of the joint the bone tends to grow outwards, forming spurs and the synovium swells producing extra synovial fluid. This causes swelling and pain, and ultimately the joint can be damaged beyond repair. This process takes a number of years to reach a stage whereby pain and discomfort are felt. Before that situation occurs, however, the joint tries to repair itself, and hyaluronic acid can take part in this process. It is mainly involved in the reparation of connective tissues such as cartilage, although there are other connective tissues which hyaluronan has been found to repair. These include skin, eyes and heart valves and hyaluronic acid can arguably be used to help repair all of them. However, it is joint tissue with which we are concerned here, and hyaluronan is an important component of articular cartilage: the type of cartilage involved in movement (knees, hips, etc), as opposed the type that forms your nose or the external part of your ears. It is believed that injections of hyaluronic acid can help to repair damaged articular cartilage. However, osteoarthritis is only one of the two forms of arthritis. The other is rheumatoid arthritis, and this is much more sinister. Rheumatoid arthritis is caused by the attack of your joints by your own immune system, although why this happens is unknown. The most likely theory is that certain infections trigger the immune system, and it then proceeds to attack the synovial joints. Cytokines are responsible for inflammation of the synovial fluid, which can also cause fever, loss of weight and appetite, and inflammation of the blood vessels. The body tries to generate more synovial fluid which causes swelling round the whole joint, putting pressure on the damaged areas, and generating even more pain. The inflammatory response commences and the whole area becomes seriously painful. The smaller joints are most commonly affected, such as the fingers and toes, but it can progress to the elbows, hips and the knees. The joints become red, swollen and finally too stiff to be used. The sinusitis eventually leads erosion of the joint and deformation. Because hyaluronic acid behaves like the synovial fluid, it is believed that it can be used to treat both forms of arthritis. It is a glycosaminoglycan, an unbranched polysaccharide of the same type as chondroitin sulfate that is commonly used to treat arthritis. It can be used to increase the viscosity of the synovial fluid, and render a more effective lubricant. However, it is in treatment of osteoarthritis that hyaluronan is most likely to find success. It is used to improve the viscosity of the synovial fluid, so providing increased lubrication to the joint and helping reduce the pain. In fact it not escaped notice that those who eat a diet rich in hyaluronic acid tend to live longer and look younger than those that do not do so. Commercial preparations are currently in use or under evaluation for disorders such as glaucoma, fractures, and detached retinas, damage to cartilage, healing ligaments and osteoarthritis. These last three are particularly of interest to arthritis sufferers, and signs are that they are effective with many cases. However, it has also been established that smoking cigarettes can negate the effect of hyaluronic acid, and excessive levels of Vitamin C can also degrade it. Estrogen treatment, however, can enhance its effect in repairing connective tissue. Zinc deficiencies have also been found to have negative results, so make sure that these factors are addressed if you are using hyaluronic acid to treat arthritis. Something to keep in mind if you are taking hyaluronic acid orally is the size of the molecule. It is a very large molecule, and suffers from the same absorption problems as chondroitin sulfate. There are smaller hyaluronan molecule versions available if you can find them, that improve the absorption through the intestine, but if not then the dose will generally be greater than expected due to the low absorption levels due to the molecule being too large to be easily absorbed through the tissues into the bloodstream.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1942) Vitamin C
Date:
August 12, 2008 01:37 PM
Vitamin C is the most widely taken nutritional supplement on the market and is available in a variety of forms, including tablets, drink mixes, crystals in capsules or bulk powdered crystals. Vitamin C is present in mother's milk and, in lower amounts, in raw cow's milk, with pasteurized milk containing only trace amounts. This vitamin is most present in the liver and least present in the muscle but needed through out the body. Vitamin C is required for the synthesis of collagen, an important structural component of blood vessels, tendons, ligaments, skin, and bone. Vitamin C can regenerate other antioxidants such as vitamin E; in the body vitamin E can regenerate C as well. This vitamin is required for the growth and repair of tissues in all parts of your body. Relatively large doses of vitamin C may cause indigestion, particularly when taken on an empty stomach. It has been shown that smokers who have diets poor in vitamin C are at a higher risk of lung-borne diseases than those smokers who have higher concentrations of Vitamin C in the blood. Biological tissues that accumulate over 100 times the level in blood plasma of vitamin C are the adrenal glands, pituitary, thymus, corpus luteum, and retina. Studies suggest the presence of large quantities of sugar either in the intestines or in the blood can slow absorption of this vitamin. Several studies have demonstrated a blood pressure lowering effect of vitamin C supplementation. Also, when consumed in high doses it appears to interfere with the blood thinning effects of warfarin by lowering prothrombin time, as noted in case reports in the 1970s so consult your doctor if on medications.. In one Study, researchers instructed patients with documented coronary artery disease to take a single oral dose of either 2 g vitamin C or a placebo. Results, the researchers discovered that high doses of vitamin C can help prevent blood platelet sticking and fight cholesterol oxidation. Also, researchers discovered this vitamin can reduce the formation of potentially carcinogenic nitrogen-containing compounds in the stomach, offering protection from stomach cancer, researchers have reported. French and German researchers found that vitamin C appeared to keep cells in the blood vessel wall from dying. The researchers, who studied immune indicators, such as serum immunoglobulin and neutrophil phagocytosis (how well your white blood cells can engulf and digest foreign bodies), concluded that vitamin C exerts a remarkable immuno-modulating action, in other words, improved immune function in all those who consumed vitamin C on a regular basis. What are deficiency symptoms for vitamin C? Scurvy is a disease resulting from lack of vitamin C, since without this vitamin, the synthesized collagen is too unstable to perform its function. Scurvy was common among those with poor access to fresh fruit and vegetables, such as remote, isolated sailors and soldiers. The amount of vitamin C required to prevent “chronic disease” appears to be more than that required for prevention of scurvy which is 30 – 60 milligrams per day. Based on scientific research, vitamin C also appears to improve oral absorption of iron, which is good news for those that are anemic. Half of us in the United States will die from heart disease. The foundation of heart disease is atherosclerosis, the narrowing of our arteries with plaque. Treatment with vitamin C has consistently resulted in improved dilation of blood vessels in individuals with atherosclerosis as well as those with angina pectoris, congestive heart failure, high cholesterol, and high blood pressure. Researchers believe this protection from cell death could explain previous study findings which suggest that vitamin C benefits blood vessel function in people with congestive heart failure. Vitamin C supplements are also generally regarded as safe in most individuals in recommended amounts, although there are rarely reported side effects including nausea, vomiting, heartburn, abdominal cramps, and headache. In addition, this vitamin is required for the synthesis of l-Carnitine, a small amino acid that is essential for the transport of fat to cellular organelles called mitochondria, for conversion to energy. If you have chronic fatigue syndrome, vitamin C may help by boosting energy production through the mitochondria.
Therefore, as in many studies of vitamin C intake and cardiovascular disease risk, it is difficult to separate the effects of vitamin C on stroke risk from the effects of other components such as diet and the consumption of fruits and vegetables. As with all dietitians an emphasis on the benefits of a diet rich in fruits and vegetables is important to maintain a healthy cardiovascular system. If one can not consume fruits and vegetables on a daily basis then supplementation of vitamin C is need in either capsule of tablet to fight the risk of disease.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1863) The Benefits of Ascorbyl Palmitate A Fat-Soluble Form of Ascorbic Acid
Date:
February 09, 2008 10:43 AM
The benefits of ascorbyl palmitate are due to the substance being a fat-soluble form of ascorbic acid which is otherwise known as vitamin C. Before discussing why being fat-soluble should be of benefit, let us first have a look at what vitamin C does for us and what its limitations are. Most people know vitamin C as the vitamin that prevents us from getting scurvy, and that limes and other citrus fruits were given to sailors to prevent them from contracting this often fatal disease on long journeys. However, important though the protection it provides against scurvy is, there are many more important uses for this important vitamin. In fact some of them are closely connected to the symptoms of scurvy. Among these are pains and swelling in the joints, and the loosening of teeth and hair loss. Scurvy is also associated with easy bruising and bleeding. All of these can be associated with loss of collagen, which is contained in connective tissues, bone and blood vessels. Collagen repairs and maintains cartilage, heals wounds and is essential for proper skin formation and the structure of ligaments, tendons, blood vessels, bones, hair and teeth. When we consider that one of the most important properties of vitamin C is the part it plays in the production of collagen in the body, then its effectiveness in alleviating the symptoms of scurvy is not difficult to understand. Vitamin C is also a strong antioxidant that destroys free radicals that kill and severely damage body cells, and cause a large variety of undesirable conditions such as atherosclerosis and cancers, and also debilitating and painful inflammatory conditions such as arthritis. Many free radicals are formed in the body as by-products of our metabolism: the generation of energy from fats and blood glucose. Others are ingested in the form of cigarette smoke and other toxins, while yet other free radicals are caused by the effect of sunlight on our skins. Natural antioxidants such as vitamins A, C and E help to keep these free radicals under control and minimize their effect. Another interesting property of vitamin C is in the synthesis of carnetine, a deficiency of which is also thought to contribute to scurvy. Carnetine is needed by the body to transport fat to the cellular mitochondria so that it can be converted to energy. Vitamin C is also believed to take part in the biochemistry that converts cholesterol to bile acids and so helps to maintain a healthy level of cholesterol in the blood. The vitamin is therefore a very useful one for the body, but it has one fault. It is water soluble, and hence cannot be stored in the body but is expelled in the urine. Had it been fat soluble it could have been able to be stored in the body fats, in the same way that vitamins A and E are, and be available for use when required. Instead any excess that is not immediately used is lost, and a fresh intake of ascorbic acid necessary on a continuous basis. Not only that, but it is only of use in areas of the body that the blood can reach. Fatty tissue is practically devoid of vitamin C, and many areas of the brain cannot be reached by substances that are insoluble in oils and fats. It also finds it difficult to penetrate the skin and the walls of body cells. This is where the benefits of ascorbyl palmitate are useful. Ascorbyl palmitate is a fat-soluble form of vitamin C and possesses all of the attributes of ascorbic acid. It is more easily absorbed by the body and can be stored in the membranes of the cells until needed. It is also a powerful antioxidant, the same as vitamin C, and is frequently used to prevent the oxidation of vegetables oils, such as on potato chips and other oily snacks. It also takes part in the biochemistry of the production of collagen and connective tissues. The usefulness of this substance comes from not only from its amphoteric nature, whereby it has one end that is water soluble and another that is fat soluble, but also by the fact that it is also amphipathic, meaning that it prefers neither one medium nor the other, and tends to collect at phase boundaries, between oil and water phases. It is particularly effective in topical uses on the skin, because it is easily absorbed into the skin tissue, and more stable than some of the other forms of vitamin C. It is also believed to protect other fat soluble antioxidants such as vitamin E from oxidation, and also to help to protect blood cell membranes from free radical attack. Although vitamin C is a very powerful vitamin, carrying out a multitude of tasks, ascorbyl palmitate has some advantages over it apart from the solubility difference. Its antioxidant properties are stronger than those of regular ascorbic acid and in fact rival those even of vitamin E, which it also helps to regenerate after its reaction with free radicals, and help to maintain a continuous supply of this powerful antioxidant. It is also a chemically neutral form of the vitamin, and unlike regular ascorbic acid, does not cause inflammation of the tissues it comes into contact with. It can also reduce sunburn due to excessive exposure to UVB when applied to the skin, and is a very stable form of the vitamin. Ascorbyl palmitate also acts as an anti-inflammatory with certain conditions, such as psoriasis where topical application helped to reduce the extent of the lesions. In fact it appears to do most of what vitamin C does, but faster and with smaller doses. So why is ascorbyl palmitate not used as the main form of vitamin C in supplements? The answer is money. Ascorbyl palmitate is considerably more expensive than regular vitamin C, and also normal ascorbic acid has some properties that the fat-soluble form does not have, such as its ability to rapidly pass through the body in the bloodstream. However, it would make sense to take a supplement consisting of both forms of vitamin C, and so combine the best properties of each. Any vitamin C supplement that is designed for maximum effect on the body should contain at least 25% of ascorbyl palmitate, the balance being ascorbic acid. That is what to look for if you are to receive the combined benefits of both water and fat soluble vitamin C.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1715) Degenerative joint disease (osteoarthritis)
Date:
August 24, 2006 03:55 PM
Degenerative joint disease (osteoarthritis) damages or destroys cartilage and its supportive collagen structure. As many as 40 million Americans, including the majority of people over age fifty, are thought to suffer from some form of this disease. Primary osteoarthritis, the “wear and tear” form, is due to normal use and age-related causes. Secondary osteoarthritis results from repeated joint trauma, inherited predisposition, or previous inflammatory conditions. While non-steroidal anti-inflammatory drugs (NSAIDs) treat symptoms only, a natural, holistic approach strives to improve the environment of the cartilage and joint as a whole by providing protective and restorative nourishment, increased circulation, decreased inflammation and reduced free radical damage. High levels of Glucosamine and Chondroitin Sulfate Widely regarded as the first defense in protecting joints, glucosamine and Chondroitin sulfate have been shown to effectively control joint pain and slow down or reverse the progression of cartilage deterioration. The integrity of joint gliding surfaces as well as the health of tendons, ligaments, joint fluids, skin, bones, heart valves and virtually all structural elements in the body is dependent upon the proper synthesis and availability of proteoglycans, integral components of joint cartilage. Glucosamine provides two components critical to the synthesis of proteoglycans: hyaluronic acid and glycosaminoglycans (GAGs). Chondroitin sulfate represents an important group of GAGs. It is not a single compound, but rather a class of compounds with different molecular weights that each have specialized functions within the body. Numerous studies have shown that long-term safety, reduction in pain and protection of cartilage with body chondroitin and glucosamine are comparable or superior to results obtained with NSAIDs. MSM. (Methylsulfonylmethane) MSM is a rich source of sulfur, a mineral required for GAG synthesis. A preliminary study suggests that MSM may help reduce pain in persons with degenerative arthritis. Gota Kola. (Centella asiatica) known to support collagen synthesis and stimulate GAG’s, Gota Kola has been used for many years in Europe to promote wound healing and blood vessel integrity. It also has been shown to improve circulation in small vessels. Turmeric. (Curcuma longa) this saffron-colored root offers a wide range of benefits. It naturally inhibits the inflammatory COX-2 enzyme, reduces pain and is a potent antioxidant that protects the liver and other cells. High antioxidant diets may inhibit joint deterioration. Bromelain. Derived from pineapple cores, Bromelain is most commonly used for healing soft tissue injuries and inflammation. It contains potent selective proteases (protein-digesting enzymes) and other substances which serve to block destruction of GAGs. Trace Minerals. Micronutrients play many distinct roles in support of healthy joint connective tissue and joint cartilage matrix. Black Pepper Extract. Bioperine is a highly concentrated extract (95% - 98% piperine) of black pepper. Used as a bioavailability enhancer, it has been shown to increase the absorption of vitamins, minerals and herbs.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1356) SAMe (S-Adenosylmethionine)
Date:
December 17, 2005 09:42 AM
Supports Healthy Nervous System and Joint Function Vital For Over 35 Biochemical Reactions Necessary For Optimum Health Promotes a Healthy Mood As the building blocks of protein, amino acids are vital to health. Next to water, amino acids in the form of proteins make up the greatest portion of our body weight. They comprise tendons, muscles and ligaments; organs and glands; hair and nails; important bodily fluids, and are a necessary part of every cell in the body. There are over 20 amino acids, separated into two categories – essential and non-essential. Essential amino acids are those that cannot be manufactured by your body, hence, it is essential that you obtain them from your diet. Non-essential amino acids can be manufactured by your body, however, your body must have the right combination of essential amino acids and supporting nutrients to optimize healthy protein maintenance, so supplementation may be desirable. Amino acids are not only absolutely integral to life, they can have a profound impact upon how clearly we think and how well we feel. SAMe (S-Adenosylmethionine) SAMe (S-adenosylmethionine) is a naturally occurring combination of the amino acid methionine and ATP (adenosine triphosphate), the body’s primary energy molecule. In this form it is sometimes referred to as “active methionine”. Research indicates that SAMe plays a vital role in nervous system health and normal cognitive function.* SAMe may support nervous system function by increasing the synthesis and recycling of certain neurotransmitters and enhancing the sensitivity of nerve receptors. SAMe is believed to positively affect a number of neurotransmitters, including serotonin, dopamine, noradrenaline and norepinephrine. Although the mechanism for SAMe’s impact upon neural function is not fully understood, there is no doubt that SAMe’s capacity as a methyl donor is of critical importance. As a methyl donor SAMe assists the body in the creation of complex organic compounds necessary for normal healthy function. Your body uses these new compounds for numerous purposes, including brain function and detoxification. This process, known as methylation or transmethylation, is vital to your body’s maintenance. SAMe may be the most effective of all methyl donors discovered to date. Research has shown that SAMe is the only methyl donor with the potential to increase transmethylation in the brain, which helps to protect it from homocysteine damage as well as increasing production of glutathione, one of the body’s most effective antioxidants. Research into the biosynthesis of SAMe has established a clear link between SAMe and folic acid, or folate. Folic Acid has been proven to provide support for healthy nervous system function and a healthy mood, and researchers believe these two nutrients work together to beneficially affect monoamine systems, which directly affect mood and cognitive function.* SAMe has also been shown to improve the synthesis of phospholipids for use in the brain, probably one of the most beneficial effects SAMe has on brain health. The benefits of SAMe extend beyond the brain and throughout the human body. For example, it may also aid in the repair of myelin, the sheath of fatty material that surrounds nerves and nerve cells everywhere in our nervous system. It’s found in all human tissue and organs and is available for use by your body in over 35 different biochemical reactions necessary for optimal health. SAMe may support joint health through transulfuration, a process that takes a certain amount of sulfur from SAMe to create glucosamine and chondroitin sulfates. This enhances proteoglycan synthesis, the molecule responsible for keeping articular (joint) cartilage lubricated. As mentioned earlier, SAMe is also important for the production of glutathione, a powerful free radical scavenger that defends your body from toxic agents and is necessary for liver detoxification. SAMe was first isolated in 1952 by G.L. Cantoni at the Laboratory of Cellular Pharmacology at the National Institutes of Health, Bethesda, Maryland. Four years later, Cantoni and a co-worker found that SAMe synthesis involves methionine and ATP. They also found that it exists in the human body only temporarily, making production in a supplemental form difficult. It took nearly ten years until improvements in technology permitted SAMe research to advance. With the discovery of a method to stabilize SAMe that overcame these manufacturing problems, U.S. patents were granted to allow the production of SAMe in a stabilized form. SAMe in its ion form, as found in human cells, has a very short life span and is rapidly metabolized into other necessary compounds as needed. Therefore, it must be manufactured in a stabilized form to prevent rapid degradation as a supplement. Once tableted, it must be enteric coated to preserve stability. This technology was not readily available until the 1990’s, hence SAMe’s long road to mainstream popularity. Dr. Joseph Zhou, Director of Laboratory Methods here at NOW, is credited with significantly improving the analytical methodology used to assure potency levels in supplemental SAMe. His work is one of the reasons SAMe is available as a supplemental with stable, guaranteed
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1019) PYCNOGENOL ® - The Ultimate Antioxidant
Date:
June 04, 2005 02:04 PM
Pycnogenol® is a breakthrough in antioxidant protection that demonstrates how important natural nutrition can be for your health. Antioxidants are a class of biological molecules that function to scavenge and neutralize free radicals. Free radicals are molecules with unpaired electrons that cause damage at the cellular level, and which unfortunately are unavoidable. Antioxidants – the most famous of which thus far have been Vitamin C and Vitamin E – work to protect living tissue by neutralizing free radicals, thereby interrupting many of their harmful activities. Pycnogenol®, one of the most powerful antioxidants yet discovered, is the proprietary name of a natural plant product made from the bark of the European coastal pine, Pinus maritima. It is 20 times more potent an antioxidant than Vitamin C, and 50 times more so than Vitamin E. Free radicals are a real threat Uniquely vulnerable targets of free radical attack that require a regular supply of antioxidants just to maintain a basic level of function include fatty acids – especially those in cell membranes – and sulfhydral proteins, which form one of the most common types of chemical bonds found in biological organisms. The importance of these substances for overall health cannot be overstated, as they are critical components not only of tissues throughout the body, but most importantly, of the principal regulatory organs – the brain and liver – and every blood vessel. Free radical attack on fatty acids – known as lipid peroxidation – and related destruction of sulfhydral proteins can lead to diminished function of cell membranes and whole organs. This, in turn, can contribute significantly to decreases in quality of life. Free radicals are believed to be active in the development of cumulative damage to the system, as well as in many of the undesirable effects of aging. Free radicals are constantly being produced due to the natural intake of oxygen and generation of energy by the body’s cells. However, their production is heightened by pollutants such as tobacco smoke, alcohol, solvents, and oxidized cholesterol from foods. Therefore, health scientists suggest we may need to increase our intake of antioxidants either from foods or from supplements – such as Vitamin A and Beta Carotene, Vitamins C and E, Selenium, Cysteine, and now, Pycnogenol®. Potent antioxidant protection from nature - Pycnogenol® Originally discovered by renowned scientist Jacques Masquelier, Pycnogenol® is a natural 85% to 95% concentrate of proanthocyanidins extracted from the bark of the Maritime Pine. Proanthocyanidins are a special class of highly bioavailable, water-soluble bioflavonoids with unparalleled free radical scavenging activity. They readily cross the Blood-Brain Barrier to provide antioxidant protection to the central nervous system, and stay in the bloodstream for approximately 72 hours. Thirty years of sound European research shows that proanthocyanidins from Pycnogenol® are highly beneficial with no evidence of adverse effects, even after more than ten years of use. They also show no loss in potency after 12 years of storage. Better health for an active life As a potent antioxidant, Pycnogenol® is valuable for protecting the liver from free radical attack. Since the liver is the main detoxifying, nutrient-assimilating, and energy-generating organ of the body, this may mean more potential for activity in your life. Pycnogenol® may also aid recovery for athletes on strenuous workout regimes and in competition. Healthy capillaries through healthy collagen A major beneficiary of the protective actions of Pycnogenol® is collagen, the most abundant protein in the body. Collagen is responsible for maintaining the integrity of “ground substance,” the basic material in functional fluids, mucus linings, and connective tissue such as tendons, ligaments, cartilage, and most importantly, blood vessels linings. It is highly vulnerable to free radical attack, and a number of discomforting and depreciating processes are associated with its destruction. There is evidence showing that Pycnogenol® can provide remarkable support for the prevention of collagen destruction, and it has received much attention for its special affinity for capillaries, the smallest blood vessels. Pycnogenol® helps strengthen capillary linings in three key ways. First, Pycnogenol® functions to scavenge the free radicals that may compromise the integrity of collagen. Second, Pycnogenol® contains catechin, which is thought to stabilize collagen by forming hydrogen bonds and cross-linking collagen. Third, Pycnogenol® is Vitamin C-sparing, meaning it can fill in for C in a number of functions; this frees some Vitamin C – required for the synthesis of hydroxproline, a major structural amino acid of collagen – for use in building collagen. People who smoke and women who take oral contraceptives can reduce their heightened risk of Vitamin C depletion by taking advantage of Pycnogenol®’s Vitamin C-sparing activity. Look to Source Naturals® for 25 mg, 50 mg, 75 mg, & 100 mg tablets of this natural wonder!
References
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=188) Joint Response and Ultra Joint Response 
Date:
June 02, 2005 01:01 PM
Many people are unaware of the multiple body systems involved with joint health. Source Naturals ULTRA JOINT RESPONSE™ is a Bio-Aligned Formula™ that goes deep to bring alignment to these multiple systems. It features structural building blocks, tissue production cofactors, and ingredients that aid the body’s mechanisms for soothing relief and antioxidant defense. Joint Support Formulations You can use ULTRA JOINT RESPONSE alone or as the core of your healthy joints program, complementing it with additional potencies and ingredients. These include: GLUCOSAMINE CHONDROITIN WITH MSM™, MSM Cream, SAME, CM COMPLEX™ Cetyl Myristoleate, and BROMELAIN. For muscle discomfort and fatigue, Source Naturals also offers you FIBRO-RESPONSE™ Bio-Aligned Formula. ULTRA JOINT RESPONSE™: BIO-ALIGNED FORMULA ULTRA JOINT RESPONSE uses scientifically researched ingredients and nutritive co-factors for a comprehensive approach to soothing, lubricating, rebuilding and aligning connective tissue, joints, tendons and ligaments. MSM dietary sulfur, glucosamine and sea cucumber provide structural building blocks that are necessary to help maintain the integrity of joints and connective tissue. Vitamins A, B-6 and C, zinc, manganese, and copper act as co-factors or parts of enzymes that play a role in connective tissue formation and maintenance. Various soothing herbs, rich in polysaccharides and other constituents, assist the body’s natural mechanisms for soothing relief. Finally, N-acetyl cysteine, grape seed, beta carotene, vitamin C, zinc, selenium, horse chestnut, turmeric, and quercetin support the body’s natural antioxidant response, thereby helping maintain the health and integrity of joints and tissues (specifically cell membranes). GLUCOSAMINE CHONDROITIN WITH MSM: HOT RESEARCHED INGREDIENTS For added support, Source Naturals offers you a formula that combines higher potencies of the most popular joint nutrients: glucosamine sulfate, chondroitin sulfate and MSM. GLUCOSAMINE CHONDROITIN COMPLEX WITH MSM provides the same amounts of chondroitin and glucosamine shown in recent research to support healthy joints—along with MSM, vitamin C, and molybdenum, for a more powerful product. Together, these ingredients promote joint, tendon and ligament flexibility and easy joint movement. FIBRO-RESPONSE: BIO-ALIGNED FORMULA Dealing with the muscle discomfort that affects millions in our society requires more than alleviating fatigue. FIBRO-RESPONSE influences specific body systems and tissues involved in joint health and muscular metabolism. Malic acid and magnesium, supplied in the same amounts used in recent research, help support muscular energy production, along with coenzyme Q10, lipoic acid and B-complex vitamins. MSM, copper, manganese, molybdenum, zinc, vitamin C, and beta carotene support healthy connective tissue, which is essential for proper joint and muscle function. Key ingredients, including N-acetyl cysteine and silymarin aid the liver in eliminating toxic waste from blood and tissues. Ingredients including lipoic acid, selenium, N-acetyl cysteine, and coenzyme Q10 support antioxidant defense, thereby helping to maintain tissue integrity. And ginkgo and GABA are among the ingredients that support clear focus and stress reduction. LIFESTYLE TIPS FOR HEALTHY JOINTS: A STRATEGY FOR WELLNESSSM Healthy lifestyle habits should be part of your individual strategy for joint wellness. Watch Your Weight: Population-based studies, including the well-known Framingham study, have consistently shown a link between obesity and challenges to joint health. Excess weight causes pressure on joints, and can speed the rate at which cartilage wears down. Eat Healthy: To support healthy joints, increase your intake of omega-3 fatty acids from salmon, sardines, flax seeds or flax oil, avoid excess protein intake, and replace animal with plant proteins when possible. You should also eat lots of organically grown fruits and vegetables, and eliminate polyunsaturated and hydrogenated oils. Exercise Regularly: Regular physical activity helps lubricate cartilage, strengthens muscles around joints, and promotes weight control. An exercise program geared to joint health includes stretching, mild weight training, and low-impact aerobics. Rest and Relaxation: Regularly scheduled rest gives your body time to recover and rebuild, allowing you to make the most of your exercise program. It’s important to know when to slow down. Supplementation: In addition to the formulas described above, Source Naturals offers a range of products that can supplement your strategy for joint wellness. These include the pineapple enzyme BROMELAIN; SAMe, a natural compound formed from the amino acid methionine, which has been found to support joint comfort and mobility; and CM COMPLEX™ Cetyl Myristoleate, a fatty acid ester shown in recent research to reduce joint discomfort.
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Glucosamine is formed in the body from glucose. This compound is found naturally occurring in the joints of the body. It is important as a precursor and stimulant of the construction of proteoglycan synthesis, which forms the basis of cartilage. Also, glucosamine is important for the synthesis of substances that compose tendons, ligaments, the respiratory system, and the mucous membranes of the digestive and respiratory tracts. 
sulfate therapy helps to prevent joint destruction. Glucosamine sulfate is responsible for helping to heal, relieve pain, reduce inflammation, and improve damage to joint tissue, without causing the side effects that are often associated with drug therapy. 
