|
Search Term: " Rhizomes "
NSAIDs vs. Curcumin: Which One Relieves Joint Pain Without Stopping Healing?   
Date:
September 14, 2026 11:22 AM
Comparative Analysis of NSAIDs versus Curcumin in Musculoskeletal Tissue RepairPrimary Biological Mechanisms and Pharmacological TargetsManaging soft tissue and joint injuries presents a persistent therapeutic challenge in musculoskeletal medicine. Acute inflammation triggers pain, localized swelling, and mechanical disability, which routinely drives patients toward pharmacological relief. For decades, nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, naproxen, celecoxib, and diclofenac have served as primary clinical interventions. While these synthetic agents effectively extinguish acute pain signals, expanding cellular and clinical research indicates that their biochemical mechanism interrupts the fundamental repair cascades required for long-term connective tissue healing. In contrast, curcumin - a natural polyphenolic compound derived from the Rhizomes of Curcuma longa (turmeric) - exhibits a distinct, multi-targeted regulatory profile that calms hyperactive inflammation while protecting the structural components of cartilage and tendon tissue.The functional divergence between these two compounds becomes clear when considering an intuitive mechanical analogy. Tissue trauma resembles damage to a commercial building, where initial inflammation functions as the construction and demolition crew tasked with clearing rubble, stabilizing the foundation, and laying down fresh structural framing. NSAIDs function like abruptly cutting electrical power to the entire work site: the noisy machinery stops instantly and the immediate disturbance ceases, but the construction workers lose the power necessary to clean the debris and erect permanent walls. Conversely, curcumin operates as an experienced site manager: it silences unnecessary chaos and prevents site vandalism while ensuring that the skilled workers - specifically chondrocytes in cartilage and tenocytes in tendons - remain fully active, supplied, and capable of completing the restoration. At the cellular level, NSAIDs exert their effects through the catalytic inhibition of cyclooxygenase enzymes, categorized as constitutive cyclooxygenase-1 (COX-1) and inducible cyclooxygenase-2 (COX-2). Membrane phospholipids damaged during injury release arachidonic acid, which COX enzymes convert into pro-inflammatory lipid mediators known as prostanoids, most notably prostaglandin E2 (PGE2). Nonselective NSAIDs block both isoforms, while selective coxibs specifically target COX-2. By shutting off PGE2 production, NSAIDs rapidly elevate pain thresholds and blunt localized swelling. However, because PGE2 also functions as a vital signaling cue for cellular recruitment, angiogenesis, and cellular proliferation, this total enzymatic shutdown strips local repair cells of the baseline signals required to orchestrate tissue regeneration. Curcumin avoids this indiscriminate pathway paralysis by acting upstream on master transcriptional control switches rather than directly neutralizing isolated enzymes. Its primary therapeutic mechanism centers on the inhibition of Nuclear Factor-kappa B (NF-kB) and Activator Protein-1 (AP-1) signaling networks. Under acute stress or chronic inflammatory loads, the NF-kB protein complex is released from its cytoplasmic inhibitor, IkBa, and translocates directly into the cell nucleus, where it drives the transcription of catabolic cytokines such as interleukin-1 beta (IL-1ß), tumor necrosis factor-alpha (TNF-a), and interleukin-6 (IL-6). Curcumin blocks the phosphorylation and degradation of IkBa, effectively keeping NF-kB trapped in the cytoplasm. By preventing this nuclear entry, curcumin attenuates the expression of pro-inflammatory cytokines and downstream matrix-degrading enzymes while preserving baseline physiological functions. Furthermore, curcumin activates the nuclear factor erythroid 2-related factor 2 (Nrf2) and antioxidant response element (ARE) pathways, which upregulate endogenous cellular antioxidants to neutralize destructive reactive oxygen species (ROS) that induce cell death in injured joints.
The Mechanisms of NSAID-Induced Inhibition in Cartilage and Tendon RepairArticular cartilage and tendons are specialized, bradytrophic connective tissues characterized by relatively low basal metabolic rates and limited endogenous vascular supplies. These physical constraints make their cellular maintenance highly vulnerable to pharmaceutical disruptions. When synthetic compounds impair cell migration, survival, or extracellular matrix secretion, the intrinsic repair capacity of these structures is substantially degraded.Cartilage maintenance depends on chondrocytes, the sole cell type residing within articular joints, which are responsible for generating and maintaining the extracellular matrix of Type II collagen and water-binding proteoglycans such as aggrecan. Because adult articular cartilage lacks a direct vascular network, major defect repair relies heavily on the recruitment and chondrogenic differentiation of subchondral mesenchymal stem cells (MSCs) through endochondral ossification. Experimental evaluations demonstrate that systemic or intra-articular NSAID exposure halts this regenerative differentiation. Both nonselective NSAIDs and selective COX-2 inhibitors interfere with chondrocyte maturation and prevent successful tissue integration following cartilage transplantation or microfracture procedures. At the cellular level, common NSAIDs - including indomethacin, ketorolac, and diclofenac - induce cell cycle arrest in chondrocytes by blocking transition from the resting G0 phase to the proliferative G1. phase, substantially reducing viable cell numbers. Concurrently, NSAIDs downregulate Bone Morphogenetic Protein-2 (BMP-2), an essential anabolic signaling molecule that orchestrates matrix synthesis. Histological analyses in animal models reveal that NSAID administration causes a marked loss of extracellular proteoglycan content and widespread chondrocyte depletion, yielding elevated modified Mankin scores that signify advanced structural degeneration. In layman's terms, proteoglycans serve as water-absorbing structural sponges that grant cartilage its elastic shock absorption. When NSAIDs deplete these molecules, the joint surface dries out, becomes brittle, and rapidly wears down under routine mechanical friction. Tendon healing is similarly susceptible to disruption by NSAIDs. Tendons operate as high-tensile structural cables composed of longitudinally arranged Type I collagen fibers, maintained by specialized fibroblasts termed tenocytes and tenoblasts. Healing after acute rupture or chronic tear progresses through an initial inflammatory phase, followed by a proliferative phase of cell migration, and culminates in a lengthy remodeling phase of collagen alignment. In vitro and in vivo studies establish that NSAIDs directly suppress the migration and proliferative capacity of tenocytes during the critical early healing window. Without an adequate cellular workforce migrating into the wound bed, provisional collagen scaffolding cannot be synthesized effectively. The disruption is particularly pronounced at the enthesis, the specialized fibrocartilaginous junction where soft tendon inserts into rigid bone. Re-establishing this transition zone requires coordinated bone remodeling and chondrogenic differentiation, both of which are hindered by COX inhibition. In animal rotator cuff repair models, early administration of NSAIDs significantly delays collagen fiber organization and impairs mechanical integration at the insertion site, resulting in a measurable decline in load-to-failure strength and overall tendon toughness. Furthermore, while prolonged inflammation contributes to pathological degeneration, the transient synthesis of PGE2 during the initial hours following injury is essential for regulating localized microvascular flow and hyperemic nutrient delivery. By eliminating this early prostanoid pulse, NSAIDs starve the repair zone of oxygen and circulating factors precisely when the cellular metabolic demand is highest. Beyond direct biochemical cytotoxicity, systemic NSAIDs introduce a physical hazard known as analgesic arthropathy. In musculoskeletal biomechanics, pain functions as a protective feedback mechanism, forcing the patient to unload an injured joint or limb to prevent structural overload. By effectively blunting the pain reflex while simultaneously undermining the cellular synthesis of proteoglycans and collagen, NSAIDs create a deceptive state of perceived recovery. Patients prematurely resume unrestricted weight-bearing and strenuous activity, placing substantial, uncompensated mechanical forces onto compromised cartilage surfaces and unhealed tendon fibers. Over time, this recurring mechanical trauma accelerates joint space narrowing, promotes microfractures in the subchondral plate, and hastens functional joint breakdown. Chondroprotective and Tenogenic Mechanisms of CurcuminIn sharp contrast to the suppressive actions of synthetic COX inhibitors, curcumin exhibits a tissue-sparing, pro-regenerative biological profile. Rather than paralyzing cellular metabolism, curcumin modulates the microenvironment by suppressing destructive catabolic enzymes while supporting the baseline anabolic signals required for cartilage and tendon reconstruction.In articular cartilage, curcumin acts as a direct chondroprotective agent by dismantling the catabolic cascade induced by pro-inflammatory cytokines. When joint tissues are exposed to elevated IL-1ß and TNF-a, chondrocytes are provoked to synthesize matrix metalloproteinases - specifically collagenases such as MMP-1, MMP-3, and MMP-13 - along with aggrecanases like ADAMTS5. These enzymes function like enzymatic shears, systematically slicing through structural Type II collagen strands and degrading aggrecan cores. Curcumin suppresses the transcription and secretion of MMP-1, MMP-3, MMP-13, and ADAMTS5 by neutralizing NF-kB and AP-1 activation. Concurrently, it upregulates Cbp/p300 Interacting Transactivator with ED-rich tail 2 (CITED2), an essential transcriptional regulator that represses matrix metalloproteinases at the genomic level. In addition to halting extracellular degradation, curcumin protects chondrocytes from inflammatory apoptosis. Exposure to oxidative stress and inflammatory cytokines typically triggers programmed cell death by activating the intrinsic caspase cascade. Curcumin suppresses this apoptotic pathway by reducing the cleavage of executioner caspase-3, downregulating the pro-apoptotic factor Bax, and elevating anti-apoptotic Bcl-2 expression. Microscopic and histological analyses of osteoarthritic cartilage treated with curcumin consistently show robust Safranin O staining, intact surface regularity, preserved chondrocyte density, and significantly reduced Osteoarthritis Research Society International (OARSI) degradation scores. Within tendon biology, curcumin promotes active tissue regeneration (tenogenesis) rather than inert scar formation. In animal models of tendon rupture and surgical repair, curcumin guides tendon-derived stem and progenitor cells (TSPCs) toward mature tenocyte differentiation. This lineage-specific differentiation is orchestrated primarily through activation of the phosphatidylinositol 3-kinase/protein kinase B (PI3K/Akt) and Wnt/ß-catenin signaling cascades. As stem cells commit to the tenogenic pathway, they significantly upregulate crucial structural and phenotypic markers, including epithelial cell adhesion molecule (EpCAM), tenomodulin, and the master tendon transcription factor Scleraxis. Through this guided differentiation, curcumin supports the preferential synthesis and organized deposition of high-tensile Type I collagen fibers, the primary architectural building blocks of healthy tendons. Injured tendons typically fill with disorganized, loose Type III collagen, which forms a structurally inferior, compliant scar. Curcumin supplementation promotes the progressive maturation from primitive Type III collagen to densely packed, parallel Type I collagen fibrils, restoring native tensile strength and mechanical breaking force. A major clinical challenge following tendon surgery is the development of peritendinous adhesions, in which excessive fibrotic scar tissue binds the healing tendon to its synovial sheath, restricting range of motion and joint gliding. Postoperative tendon repair involves a balance between extrinsic healing (in which exterior fibroblasts infiltrate the defect and deposit messy scar tissue) and intrinsic healing (in which tenocytes within the tendon substance reconstruct the matrix). Curcumin suppresses excessive peritendinous inflammation and extrinsic fibrosis while accelerating intrinsic tenocyte repair. Biomechanical testing confirms that local or systemic curcumin administration yields lower adhesion scores, increased gliding distances, and superior functional mobility without sacrificing structural load-bearing capacity. Comparative Clinical Efficacy and Systemic Safety ProfilesTranslating cellular findings into clinical practice requires weighing therapeutic outcomes against systemic safety profiles. While synthetic NSAIDs deliver potent, rapid analgesia during acute musculoskeletal pain events, their chronic administration is constrained by systemic toxicities across multiple organ systems.In randomized, active-controlled clinical trials of knee osteoarthritis, optimized curcumin preparations have demonstrated clinical pain reduction and functional recovery comparable to standard therapeutic doses of NSAIDs. In a randomized, open-label parallel-arm study evaluating 139 patients with symptomatic knee osteoarthritis, subjects received either 500 mg of a bio-enhanced curcumin extract three times daily or 50 mg of diclofenac sodium twice daily for 28 consecutive days. Patients treated with curcumin demonstrated comparable improvements in pain intensity on the Visual Analogue Scale (VAS) and functional scores on the Knee Injury and Osteoarthritis Outcome Score (KOOS) at days 14 and 28, showing no statistically significant difference in therapeutic efficacy compared to diclofenac. However, the systemic tolerability profiles between the treatments diverged markedly. Overall adverse events occurred in only 13% of the curcumin group compared to 38% of the diclofenac cohort. In the diclofenac arm, 28% of patients developed dyspeptic symptoms severe enough to require concurrent treatment with H2-receptor antagonists or proton pump inhibitors to prevent mucosal ulceration, whereas no patients in the curcumin cohort required gastroprotective intervention. Furthermore, the curcumin cohort experienced a significant reduction in flatulence and digestive discomfort, demonstrating beneficial gastric and intestinal cytoprotective effects. These safety observations are consistent across broader systematic reviews and meta-analyses. Nonsteroidal anti-inflammatory agents inherently compromise gastrointestinal integrity by systematically depleting cytoprotective prostaglandins, leaving the gastric epithelium vulnerable to acid erosion and hemorrhage. In addition, systemic inhibition of renal and vascular COX enzymes by NSAIDs reduces renal perfusion and disrupts the balance between prostacyclin and thromboxane, elevating the risk of fluid retention, hypertension, and adverse cardiovascular thrombotic events. Curcumin does not suppress these physiological prostanoid pathways, making it free from ulcerogenic, nephrotoxic, and cardiotoxic properties at therapeutic dosages.
A longstanding limitation of standard curcumin supplementation in clinical settings has been its low oral bioavailability. Native curcuminoids are highly lipophilic, poorly soluble in aqueous gastric fluids, and subject to rapid hepatic and intestinal phase II metabolism into inactive glucuronides and sulfates, leading to swift biliary and fecal excretion. Consequently, raw culinary turmeric powders struggle to achieve the therapeutic systemic circulating concentrations required to reach poorly vascularized joint and tendon compartments. Modern pharmacognosy has addressed this pharmacodynamic hurdle through advanced delivery formulations. Modern strategies - such as co-administration with the natural alkaloid piperine (which inhibits hepatic glucuronidation), micellar dispersions, phytosomal phospholipid complexes, and bio-enhanced submicron dispersions - elevate systemic blood bioavailability by ten- to thirty-fold compared to unformulated extracts. These modern delivery platforms ensure that therapeutic concentrations reach synovial fluid, subchondral bone, and fibrous tendon sheaths without requiring excessive oral dosing. Conclusions and Translational Clinical ImplicationsThe biological and clinical evidence reveals distinct physiological paths for NSAIDs and curcumin in orthopedic recovery. While NSAIDs remain powerful tools for the brief alleviation of acute, unmanageable pain, their ongoing administration during active tissue healing presents substantial biological compromises. Tendons and cartilage require a controlled, transient inflammatory cascade to signal cell recruitment, stimulate stem cell differentiation, and direct extracellular matrix synthesis. By completely shutting down cyclooxygenase enzymes and depleting local prostaglandins, NSAIDs disrupt this regenerative cascade. The resulting cellular consequences - including chondrocyte cell cycle arrest, proteoglycan loss, suppression of tenocyte migration, and weakened collagen tensile strength at the tendon-to-bone interface - demonstrate that pain relief from NSAIDs frequently comes at the cost of the structural integrity of healing connective tissues.In contrast, curcumin provides a tissue-preserving alternative that decouples pain and inflammation control from cellular suppression. Operating upstream at the level of NF-kB and AP-1 transcriptional activation, curcumin attenuates the expression of pro-inflammatory cytokines while leaving the physiological baseline of cellular metabolism intact. In cartilage, it actively represses the matrix-degrading enzymes MMP-1, MMP-3, MMP-13, and ADAMTS5, maintains water-binding proteoglycan content, and protects chondrocytes from inflammatory apoptosis. In damaged tendons, curcumin stimulates tenogenic differentiation of local stem cells via PI3K/Akt signaling, supports the proper maturation of dense Type I collagen fibers, and prevents restrictive peritendinous scar adhesions, preserving both joint mobility and mechanical breaking strength. From a translational perspective, these findings indicate that clinical protocols should reconsider relying on continuous NSAIDs as the default intervention for connective tissue injuries, post-surgical recovery, and chronic degenerative conditions. Where synthetic NSAIDs are deemed necessary, their use should be confined to short-term acute flare-ups to avoid interrupting early tissue remodeling. For long-term joint preservation, ongoing tendinopathy rehabilitation, and chronic osteoarthritis management, optimized bio-enhanced curcumin formulations deliver pain relief and functional restoration comparable to conventional pharmaceuticals, all while preserving the biological processes required for lasting musculoskeletal repair. References: NSAID therapy effects on healing of bone, tendon, and the enthesis The Detrimental Effects of Systemic Ibuprofen Delivery on Tendon Conservative management of symptomatic knee osteoarthritis - PMC Positives and negatives of nonsteroidal anti-inflammatory drugs in (PDF) Conservative management of symptomatic knee osteoarthritis Non-steroidal anti-inflammatory drugs influence cartilage healing Is Curcumine Useful in the Treatment and Prevention of ... - PMC - NIH Efficacy and mechanisms of curcumin in the treatment of osteoarthritis Biological actions of curcumin on articular chondrocytes - PubMed Curcumin slows osteoarthritis progression and relieves ... - PMC - NIH Do Nonsteroidal Anti-Inflammatory Drugs Have a Deleterious Effect Anti-inflammatory management for tendon injuries - friends or foes? The mechanistic role of curcumin on matrix metalloproteinases in Therapeutic effects of turmeric or curcumin extract on pain and Curcumin inhibits chondrocyte apoptosis and inflammation in ... - PMC Analysis of the mechanism of curcumin against osteoarthritis using Synergistic enhancement of tendon-to-bone healing via anti ... - PMC A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial Safety and efficacy of curcumin versus diclofenac in knee osteoarthritis A randomized, pilot study to assess the efficacy and safety ... - PubMed Effectiveness of curcuminoids in the treatment of knee osteoarthritis THE EFFECTS OF TRADITIONAL STRENGTHENING EXERCISES Putting Some Muscle into Osteoarthritis | Annals of Internal Medicine Do Nonsteroidal Anti-Inflammatory Drugs Have a Deleterious Effect Calebin A, a Compound of Turmeric, Down-Regulates Inflammation The Effect of Non-Steroidal Anti-Inflammatory Drugs on Tendon-to Chiropractor in Toronto, ON, Canada :: Head and Neck Pain Investigation of the association of long-term NSAID use with ... - PMC Curcumin Improves Functional Recovery of Ruptured Tendon by Chemically modified curcumin (CMC2.24) alleviates osteoarthritis Curcumin improves age-related and surgically induced osteoarthritis (PDF) Curcumin Improves Functional Recovery of Ruptured Tendon Investigation of the effects of umbilical cord-derived mesenchymal Effect of curcumin-loaded polycaprolactone scaffold on Achilles Controlled release of curcumin from curcumin-loaded nanomicelles Efficacy and safety of combination of curcuminoid complex ... - PMC The efficacy of Curcuma Longa L. extract as an adjuvant therapy in
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6653) Turmeric Vs Curcumin? 
Date:
September 18, 2020 02:50 PM
Turmeric "Curcuma longa" is the plant that has been a part of Indian and Asian cuisine and medicine for thousands of years. Turmeric Rhizomes like the root of the plant contain compounds called curcuminoids. This family of compounds is called (Curcumin), and has been shown to have powerful benefits for the brain, heart, cellular immune response, and healthy inflammation response in numerous clinical studies around the world.* So in a nutshell, Turmeric is the "whole Root" and Curcumin is a compound in the root that does all the heavy lifting to fight inflammation, improve immunity, benefits the heart and brain, ect. Look for a supplement that is standardized to the curcumin to ensure bang for the buck.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6365) Interaction of turmeric (Curcuma longaL.) with beneficial microbes
Date:
October 09, 2017 01:14 PM
Turmeric is a trendy item now. Many people are beginning to add it to their diets. It is supposed to have important health benefits. This talks about how it interacts with the body's beneficial microbes. Since these do matter it is good to kow if what we're eating will have a negative effect on them. If it does you may find your body out of balance. You will be able to feel the difference when that happens. Key Takeaways:
"The present review focuses on the rhizobacterial and endophytic bacterial and fungal populations associated with the turmeric." Read more: https://link.springer.com/article/10.1007/s13205-017-0971-7
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5323) Can Butterbur Extract Help with Bladder Incontinence?
Date:
October 30, 2013 09:56 PM
What is Butterbur  It is a shrub that usually grows in marshy ground. It is found in North America, Europe, and Asia. In ancient times, its leaves were used to wrap butter when it was warm. Despite the rather interesting use, it is a plant that has been used for medicinal purposes for quite a while now. It has over time proved effective for clearing headaches, reducing pain, fever, anxiety, and problems with the urinary tract.Butterbur extract is derived from the roots, leaves and Rhizomes. It is used in the manufacturing of tablets. Topically, it treats allergies, clears migraines and asthma. How it helps elevate incontinence The traditional use of butterbur in treating problems in the urinary tract is still applicable today even in modern medicine. Normally, it is neurons in the brain and in the bladder's smooth muscles that involuntarily influence the muscle that surrounds the bladder, referred to as detrusor muscle. The detrusor muscle will contract and expand depending on the amount of urine present in the bladder. Incontinence results when the smooth muscle in the bladder contracts without any warning whatsoever. It is characterized by overly frequent urination, which is more than 3 times in 24 hours, urgency and leaking. The extract works by relaxing the detrusor muscle which reduces pressure on the bladder. Its active ingredient is a compound known as petasin. The results can be seen after a minimum of 4 weeks. By the eighth week, they are even more pronounced. Patients can improve from a minimum of 30 minutes urination intervals to 150 minutes. There are absolutely no side effects. It is not recommended for expectant mothers, or during lactation. However, it should be noted that unsaturated pyrrolizidine alkaloids (PA) are present in the natural form which could lead to liver damage. However, after processing, the P.A.s are removed. It is always safe to check whether the processed one has got any. References:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2867) What Is Kava Root?
Date:
December 19, 2012 03:53 PM
Kava root or piper methysticum is a kind of shrub that can be found all throughout the South Pacific islands. Locally called as kava kava, this plant is a close relative of black pepper. Its shrubs have woody roots or Rhizomes that contain medicinal properties. People in the South Pacific islands use kava mainly during traditional ceremonies and they have been using this herb as medicine for centuries already. Traditionally, kava is prepared as a tea or an intoxicating ceremonial beverage. But nowadays, it now comes into several forms such as capsules, extract forms, liquids, tablets, and even topical creams. One of the main benefits of kava is that it promotes relaxation. Calming effects of kava Its calming effects are due to a substance called kavalactone. It works almost exactly like a mild sedative and muscle tension reliever. Taking supplements with kava root induces sleep without the hangover effects. Because of that, kava root can help a person sleep easier. Additionally, the quality of the sleep is also improved. Kava can also elevate the mood of a person promoting the sense of well-being and satisfaction. Kavalactone has calming effects as it can interfere with the brain activity by slightly stimulating the brain waves which eventually make people feel better. Kava is definitely not addictive but its effects may decrease with regular use. Reduce Anxiety The calming effects of kava root can relieve anxiety, restlessness and some other stress-related symptoms like muscle tension and spasm. Another active compound that naturally occurs in kava is the flavokawain B which is known as a cancer-fighting property. Other potential benefits of kava root include treatment for ADHD or attention deficit disorder, depression and migraine. When applied topically, kava creams and lotions hastens the healing ability of the skin and treat several skin diseases like leprosy. If taken improperly, kava supplements can only bring about adversarial effects such as drowsiness, dizziness, gastrointestinal issues and tremors. Nevertheless, kava can still be very beneficial most especially if taken properly.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2756) Ginger And Its Use To Help In Stomach Upset
Date:
June 29, 2012 01:39 PM
Ginger Root Ginger is the root of an herbal plant that is usually consumed as medicine or used in food as a spice to help in digestion system in your stomach. The Rhizomes are usually very juicy, fleshy and with mild taste when young. These can be pickled in vinegar as a snack or sometimes be cooked as an ingredient in a variety of food. It can also be added to boiling water to come up with ginger flavored tea. The same is also used to make candy. When it matures, it appears dry and its juice is extremely potent. It is still used as a spice in most foods. The uses are unlimited but in this article, we are going to discuss how it helps with stomach upset. History of Ginger Throughout history, ginger has been used for stomach upset in many places around the world. After a very heavy feast, ancient Romans would consume it to help soothe their full stomachs. Chinese and other ancient mariners used it to sustain seasickness. Indians used it as a universal medicine as they believed it treated everything. Current Uses of the herb Currently, research has shown that ginger truly does help ease an upset stomach. There are many ways through which it can be used to relieve an upset stomach. A good example is by taking it before meals. It enhances a good environment for digestion before the food gets to the stomach. This will ensure that digestion kicks off immediately after the food is consumed and hence prevents stomach upset. People with motion sickness can take ginger to help suppress the symptoms. How it works Ginger has two component; gingerol and shogaol. These are the components that enhance the function of digestive juices like saliva, bile and other gastric secretions. When these juices are stimulated to work efficiently, they enhance digestion in an individual starting from as early as when the food is still in the mouth. This ensures that all digestion steps are undergone effectively without skipping. When whole and dry food get to the stomach, it becomes hard to digest as the stomach has no teeth to help break it down and lubricate it for swift movement. Ginger is also known to help the stomach muscles in effective movement of food. If the tract muscles do not give enough room for movement, indigestion may occur. That is what leads to nausea in an individual. The herb curbs the serotonin receptors to ensure there is no vomit message sent to the brain. Ginger also helps in the immediate emptying of the stomach contents to the small intestine. Conclusion Ginger works to help reduce stomach upset which can arise as a result of operation, overeating, sea and motion sickness. The effectiveness of this medicinal herb should not be undermined as it has helped many to get the desired relief from the uncomfortable feeling of stomach upset. Use it when you feel nauseas or even to help relieve you of gas from the stomach.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2661) How DoesTurmeric Help Improve Your Health?
Date:
March 22, 2012 07:42 AM
Turmeric - Curcumin This is a perennial herbaceous plant which belongs to the ginger family making it an important plant because of its active ingredient, curcumin and other properties which makes it avery useful plant in terms of health when used. The Rhizomes of turmericare gathered annually for preparation of various health products or foods or taken on its own as they are known to have greater concentrations of curcumin and other substances which are essential for good health. When turmeric is taken, it improves one's health in the following ways: Weight loss; for those people who are overweight and obese, they always face a challenge on how they can get rid of some extra weight as it is associated with negative health implications and on the other hand fats such as belly fat decrease one's self esteem. Turmeric is one of the herbs that if mixed with food will increase the rate of metabolism which will consequently help in fat loss which will ultimately have an effect on the weight. Thereforemanageable weight will always ensure that one is not at risk of developing cardiovascular heart diseases and other lifestyle diseases which will ultimately promote good health. Cancer and turmeric; cancer is one of the killer diseases which was very common in developed countries but nowadays it is very rampant even in developing countries. By taking turmeric, the active ingredients in it will help in stopping and preventing the development of cancer more especially prostate cancer which affects men. This herb interferes with the abnormal cell division of the cells hence leading to a stop or prevention of cancer progression thus health improvement. It is important to note that turmeric is also very effective in preventing other types of cancers for example breast cancer from spreading to other parts of the body such as the lungs. The effectiveness of turmeric in fighting cancer can be increased by mixing it with cauliflower flower. Detoxification; turmeric is rich antimicrobial properties, antiseptic properties which make it a very useful plant when it comes to cleansing of the body. The body is usually bombarded with a lot of chemicals and toxins from the environment and what is eaten hence need to cleanse it. This can be achieved by taking turmeric on its own or mixing it with other foods and taking it two to three times a day for a period of about one month. This will go along way in detoxifying the body more especially the liver which will make it more healthy hence work better as it is one of the largest organ in the body. Fighting inflammation; this is one of the common symptom of very many ailments and by taking turmeric, it will be able to fight inflammation resulting in improved and good health. It has also been associated with the reduction or clearing of symptoms of arthritis (rheumatoid arthritis and osteoarthritis). This will improvemotion of the patient which willfinally have an impact on performance of the patient thus have a positive impact on the health of those with these conditions. Turmeric can also be used as a natural disinfectant for example when burns and cuts occur at home, it can be applied thus hastening the healing process. As you can see, turmeric with curcumin has a wide range of uses, you too should have this wonderful herb on hand in case of emergencies.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2614) How Much Turmeric Should Be Taken For Alzheimer's?
Date:
October 05, 2011 02:08 PM
Turmeric is commonly used as a culinary spice or ingredient. It is dried in extreme temperatures of ovens and ground into a yellow to orange powder. This spice is common in many Asian dishes. Aside from its culinary use, it can also be helpful in maintaining the health of the human body. The known active ingredient of turmeric is Curcumin. This chemical substance has a unique slightly metallic taste and peppery in flavor. It also has a mustard–like aroma. Hence, it is considered to be an important condiment in many Middle Eastern recipes. In addition to Curcumin, turmeric consists of about 5 % of essential oils. With its many health benefits, one of the most interesting is its effect on the brain in helping prevent the onset of Alzheimer’s disease. Clinical studies and surveys reveal that people who consume large quantities of curry have a lesser risk and incidence of having Alzheimer’s disease. Therefore, intensive studies are being conducted to test and prove its safety and effectiveness as a chemical substance which can greatly help in the prevention of the increasing number of Alzheimer’s disease cases. Other factors are also considered such as the individual’s diet, familial history, social and economic status as well as lifestyle. Alzheimer’s disease has been closely related to the increasing damage of brain cells due to oxidation. This brain damage will significantly cause an effect to the person’s memory thus Alzheimer’s disease occur. Curcumin in the turmeric has the potent capacity to prevent this cellular damage thus slowing the development of such disease. Studies have also shown that Curcumin can significantly impede certain mechanisms that are involved in the progress of Alzheimer’s disease. Aside from its benefit in decreasing the risk of Alzheimer’s disease, turmeric also has a potential anti – inflammatory property and can effectively regulate blood cholesterol levels. The recommended dosage of turmeric has not yet been officially established. Therefore, if you are planning to supplement with turmeric, it would be best that you should consult your doctor. The dosage of this supplement varies from person to person in terms of age, weight, other health conditions and status of his/her Alzheimer’s disease.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2482) The Health Benefits of Turmeric
Date:
January 27, 2011 05:16 PM
Turmeric is a member of the ginger family, often called Indian saffron because of its use as a yellow dye, particularly in cookery. The spice comes from boiled turmeric Rhizomes that are dried and then ground into a fine powder. Its main active ingredient is curcumin, which offers a number of medicinal uses including its traditional use in Ayurvedic medicine as an antibacterial antiseptic for cuts and burns. It also possesses strong anti-inflammatory properties and is used to treat the symptoms of irritable bowel syndrome and other disorders of the digestive system. Turmeric is strongly antioxidant and neutralizes the free radicals that can accelerate the signs of aging, such as wrinkles and liver spots, and it is also believed to be effective in treating some cancers, although more research is needed on these potential properties. Turmeric is a good liver tonic, helping to protect it from certain toxins such as alcohols that destroy liver cells of taken in excess. It also helps to reduce the incidence of blood clots due to its anti-platelet properties, and it is little wonder that in traditional Ayurvedic medicine using turmeric was regarded as a sign of wealth, and a means of curing most ailments.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2225) Licorice Root
Date:
May 23, 2008 11:53 AM
Medical professionals, especially in Europe and Japan, have been using licorice more and more in medicine. The Chinese consider licorice to be a superior balancing and harmonizing agent, so it is added to many herbal formulas. It is reputed in many countries, including the United States, to be a treatment for stomach, intestinal and many other problems. What is it used for? Antioxidant Properties Licorice is being studied for its effects against oxidation of LDL cholesterol, which is a major component in atherosclerosis. Approximately 300 different phytonutrient compounds found in natural licorice are considered possible antioxidants. Anti-Viral Properties Licorice is being tested for its ability to help prevent certain viruses from replicating themselves in body cells. It appears to stimulate the immune system into producing interferon, which is known for its anti-viral effects. It is an effective aid in treating herpes and hepatitis. Promising results are also being reported in tests using licorice to combat SARS, influenza and HIV. Stomach and Intestinal Problems Licorice is a natural home remedy for heartburn, gastritis and acid reflux. It helps to promote new cell growth in the lining of the stomach. It also enhances the stomach's self-protecting abilities. Licorice has been used to treat peptic ulcers and aid in healing other types of ulcers. Throat and Respiratory Problems Licorice is widely known in the world of alternative medicine as an expectorant and cough suppressant. Colds and flu have been treated with licorice since the days of the Romans. Many over-the-counter cough medicines contain licorice extract because it soothes the mucous membranes. Other Medicinal Properties
Is Licorice Safe? Licorice is not recommended for use by people who suffer from diabetes mellitus, heart disease, hypertension or kidney disease. It is also not recommended for use by women who are pregnant or breast-feeding. Side Effects Licorice, although not thought to suppress the immune system like pharmaceutical cortisones, may cause similar side effects in high doses. Some of these include weight gain, fluid retention and high blood pressure. Description and Cultivation The licorice plant stands up to five feet tall. It has spikes of lilac-colored flowers that have bean-like pods containing three or four seeds apiece. The root, which is used most frequently, reaches underground about three feet and branches into networks of Rhizomes. After three to five years, the roots and Rhizomes are cleaned, pulped, boiled and then concentrated by evaporation. The root, if kept dry, will keep for an indefinite amount of time. If the licorice is powdered, it should be stored in an airtight container. Licorice has been used for centuries in conjunction with established medicine, as an alternative herbal medicine, and as an herbal confection in many parts of the world. It is noted for its medicinal value in treating stomach, intestinal and other ailments, including helping to stimulate the immune system. Studies are ongoing to discover more potential uses for this naturally sweet herb.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1797) ButterBur Extract
Date:
April 29, 2008 10:49 AM
Butterbur extract is taken mainly from the rhizome, root and leaves of the butterbur, a member of the daisy family. They are very hardy and have creeping underground Rhizomes and large leaves like those of rhubarb. Another name given to it is the sweet Coltsfoot, and they generally grow in the temperate climates of Europe, North Africa and South west Asia. They like damp conditions, specifically marshes and ditches, and also riverbanks where there are always plentiful supplies of moisture. It has been used by Native Americans for headaches and inflammation, and has been shown to be an effective remedy for hay fever and to provide relief from painful menstrual cramps. Butterbur has also been used throughout the middle Ages to treat fever and the plague, and has been recorded in the seventeenth century as being used for asthma, wounds and coughs. However, one of its most important applications is in restore bladder function in the incontinent and semi-incontinent. Urinary incontinence is typified by an unusually high frequency of urination – more than 8 times a day, an immediate strong urge to pass water or leaking and involuntary urination. Any two of these three indicates urinary incontinence. As people age their bladders become smaller, and by definition the periods between urination will reduce. This does not, however, suggest that bladder size is the cause of urinary incontinence. Urination is caused by the contraction of the smooth layered muscle that surrounds the bladder, called the detrusor, a contraction in turn caused by neurons both in the brain and in the detrusor itself. This naturally contracts and expands according to the volume of urine in the bladder, and once the bladder is about half full the brain will tell you that the detrusor is ready to contract to expel the urine. However, if the time is not convenient, the cortex will suppress this desire until a more convenient time. In incontinence, the desire is suppressed but the neurons still fire to contract the detrusor, expelling urine at inconvenient moments. Butterbur contains the sesquiterpenes petasin and isopetasin, which are known to reduce spasms in smooth muscle tissue and in vascular walls. It can therefore be used to control the involuntary spasms that cause urine leakage or expulsion against the patient’s wishes. These sesquiterpenes are at highest concentration in the roots of the plant. The effect that the sesquiterpenes have in inhibiting the synthesis of leukotriene in leukocytes tends to support this effect, since leukotrienes can cause contraction of vascular and smooth muscle tissue. Not only this, but the spasmolytic effect could also be explained by the inhibition of cellular calcium caused by the petasin isomers. Many studies have indicated that the effectiveness of butterbur extract is also useful in the prevention of migraines. There has been a lot of research carried out on the use of butterbur extract on migraine sufferers, and the effective dose appears to about 75 mg twice daily. There is little evidence of it being a cure but as a prophylactic there appears no doubt of its efficacy: there have been too many positive results against placebos for its effect to be deniable. It is significant that leukotriene can cause constriction of the small blood vessels in the veins, and so affect the flow of blood. Butterbur, in inhibiting its biochemical production, helps to keep these blood vessels open. Lekotrienes are also important components of inflammation, and altogether it appears that whatever the real cause of migraine, the petasin isomers in butterbur have an effect in inhibiting its initiation. Add to that the potential reduction in calcium content that can cause blood vessels to become less flexible, and the argument for its effectiveness is both irrefutable and well explained. In one example of such a double blind study that is representative of many, a group of patients given 50 mg butterbur extract twice a day for twelve weeks experienced a 60% reduction in the frequency of attacks, a reduction in the severity of the attacks they did have, and a reduction in the length of the attacks. Although the vascular theory of the cause of migraine is no longer supported, maintenance of the vascular system appears to at least reduce the likelihood of attacks. The effect of butterbur on asthma and other allergic reactions is also well documented. This again is due to its anti-spasmodic properties and inhibitory effect on the inflammatory immune response through the inhibition of leukotriene synthesis and the consequent positive effect on the metabolism of prostaglandin. Prostaglandins also constrict vascular smooth muscle cells, regulate the mediation of the inflammatory response and constrict general smooth muscle cells. All of these can lead a to a variety of disorders cause by smooth muscle spasms in additional to urinary incontinence, such as menstrual cramps, liver and gastrointestinal disorders and asthmatic conditions. In one study of allergic rhinitis, administration of butterbur extract appeared to result in a reduction in the histamine and leukotriene content of nasal fluids and no difference was noticed between this treatment and histamine treatment. This was a useful study because histamines causes drowsiness and butterbur can be used as a substitute for histamine without the sedative effect. A study in Germany in 1993 has shown that the stomach ulceration caused by the anti-inflammatory medications for arthritis was reduced by the administration of butterbur extract Cetirizine is a commonly prescribed prescription treatment for allergic conditions, and studies comparing that with butterbur demonstrated them to be equally effecting in reducing the symptoms typical of allergic reactions such as sneezing, runny nose and nasal congestion. 50% of the patients in the group took each and there was no difference in results. Again it was explained by the petasin limiting the production of leukotriene and histamine, both of which are produced by the immune response and promote mucous secretions and inflammation. They also constrict airways that can be serious to asthma sufferers
These studies are simply providing scientific evidence and explanations for the tradition use of this plant for such conditions. Butterbur has been used for centuries to treat such conditions all over Western Europe, and once again the use of traditional medicine has been supported by modern investigative techniques.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1776) Detox your Body with Wasabi Rhizome
Date:
January 29, 2008 10:30 AM
The Wasabi rhizome, the underground fleshy stem of the wasabia japonica plant, is prized not only for its fiery flavour but also its effect in detoxifying the liver. However, make sure that you are getting the real McCoy since many restaurants in the USA do not use the genuine paste. The wasabi is a plant of the cruciferous family, the same family as cabbage, broccoli, turnip, radish, horseradish and mustard, and is native to Japan and Korea and now grown on the Pacific coast of Canada. It grows best in temperate to cold climates, especially in mountainous areas where there are plenty of cold streams. Anybody who regularly enjoys sashimi and sushi should be familiar with the wasabi rhizome, that green lump of paste lying on the side of the plate. It is hot and fiery, although not in the same way as the chilli pepper that is fiery on the tongue and in the mouth. This tends to affect the sinuses more, and leaves a sweetish taste once the initial heat has dissipated. However, it is not always what it should be. The last comment there refers to the practise, especially in the USA, of using dyed common horseradish as wasabi paste, so be careful of that since the two are not equivalent in the health benefits they impart to your body. Although of the same family as the horseradish, and sometimes termed the Japanese horseradish, ordinary horseradish does not have the same health benefits as genuine wasabi, and does not contain the same active ingredients so do not confuse the two. Real wasabi is normally used grated, and there are specific techniques that should be used to grate wasabi Rhizomes to bring out the fullness of the flavour. True grated wasabi should be of a natural pale greenish color rather than the brighter green normally associated with sushi restaurant wasabi. Traditionally, wasabi rhizome is used as a condiment with sushi, although their leaves can also be used in salad dressings and or as a delicacy pickled in soy sauce or sake brine. The genuine vegetable is difficult to cultivate which explains why ordinary horseradish is dyed and used in its stead, and the vast majority of non-Japanese do not know the difference because it is likely to be all they have consumed under the name of wasabi. The health benefits of the genuine article, however, are considerable greater. So that’s what it is, but what does it do? What are the health benefits of wasabi Rhizomes and why are they considered to be so good for your liver? Wasabi Rhizomes contain substances that are very effective in detoxifying you liver, and that are also very strong antioxidants that provide you with good overall health benefits in their capacity to destroy the free radicals created by the pollution of modern living. The active antioxidants in the rhizome are precursors of isothiocyanates, which are known as phytochemicals. These are chemicals that can protect or prevent diseases through its antioxidant properties. The term ‘precursor’ means that the isothiocyanates are synthesized by your body from the nutrients contained in the wasabi rhizome. Other examples of phytochemicals that you may have heard of are carotenoids, flavonoids and polyphenols that also possess antioxidant properties. Other antioxidants are vitamins A and E, which is why these are used in anti-wrinkle creams, since their anti-oxidant effect helps to prevent the free radicals destroying the skin cells in the dermis and epidermis that leads to the wrinkles associated with aging. Wasabi is equally effective as an antioxidant, although it has other properties that are important to your liver. The liver is your body’s chemical plant. That is where most of the chemical reactions take place that are essential for life. If your liver is unhealthy you can develop diseases such as hepatitis and cirrhosis, and a healthy liver is essential for life let alone a healthy life. Wasabi helps to detoxify and clean out your liver. Apart from creating the wide variety of enzymes needed to process your food, and controlling the vast majority of the biochemistry of your body, your liver is also your detoxification plant that coverts toxins into biodegradable molecules that your waste disposal system can evacuate without harm. This occurs in two phases. Phase I coverts the toxin to a form that your body can further process (the bioactive form), and Phase II breaks it down into a form that your kidneys can handle and eject it in your urine. Isothiocyanates are involved in the production of the enzymes that enable the chemical reactions of Phase II to proceed. They allow your body to cleanse itself of toxins, and without this process you would be less healthy and more prone to cancers and other undesirable conditions and diseases in your body. It is becoming more important in this modern age with its increasing natural and synthetic pollution that your liver is working at peak efficiency. Your liver is equally as important to you as your heart and brain, and without it you cannot survive. Wasabi also contains glucosinolates that help the isothiocyanates to induce the production of Phase II enzymes, and it is general believed that eating this tuber cab help protect you against stomach, colon and breast cancers as well as help your cardiovascular system and blood clotting. An interesting fact is how wasabi rhizome came to be traditionally served with raw fish. The isothiocyanates precursors, and the glucosinolates that wasabi also contains, apparently help to destroy the bacteria associated with raw fish, and help prevent disease and illness. It was likely found healthier to include a dollop of this green paste with your sushi than not, and so the use of common horseradish might be somewhat questionable if it has less of an effect. Make sure, therefore, that your have the real thing, and apart from any specific health considerations associated with eating raw fish, you are best advised to take it as a supplement to help Detox your liver rather than visit sushi bars for your consumption. It will also help your wallet!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1709) Curcumin - Turmeric Extract
Date:
August 19, 2005 12:47 PM
Turmeric- History and Traditional Usage
Native to Southeast Asia, Curcuma longa is a tall
In addition to its
Turmeric is named in
Protects cells and tissues by fighting free radicals.* Supports joint function*
The numerous beneficial
Curcumin demonstrates Animal studies- In vivo protective effects
Through its free radical scavenging Human Trials
Curcumin exhibits free-radical scavenging ability when
Bioperine-Nature’s Absorption Enhancer
Traditional Ayurvedic herbal
Curcumin is poorly absorbed in the intestinal Scientific References
© 2002 *This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=734) HERBS FOR HEALTHY KIDNEYS 
Date:
July 14, 2005 03:41 PM
HERBS FOR HEALTHY KIDNEYS The kidneys are another important filtering system for the body. Large quantities of blood pass through the body eliminating toxins in urine. They help the body maintain a constant and healthy environment by adjusting the body’s electrolyte balance, manufacturing hormones that regulate blood pressure, controlling calcium metabolism and aiding in the production of red blood cells. Keeping the kidneys healthy is essential for a healthy body. Parsley is a powerful diuretic often used to treat kidney conditions. It inhibits the reabsorption of salt by body tissues increasing the diuretic activity of the kidneys. It helps to increase and improve urination allowing for toxins to be removed through the kidneys. One of the components found in parsley seeds is an ingredient used in a drug to treat urinary tract infections. A volatile oil in yarrow known as azulene and related compounds have been shown in studies to have anti-inflammatory properties which may help relieve urination problems. It also helps regulate and improve the function of the liver. Dandelion is a natural diuretic and contains a high potassium content. This helps the body replenish and stabilize potassium levels as they are depleted with many diuretics. It can be used to relieve water retention. Dandelion gently increases the urine flow while keeping the potassium and electrolytes in balance. Studies in humans have shown that the Rhizomes and roots increases the flow of bile which is beneficial for liver disorders, gallstones, jaundice, and the bile duct. Bitter substances found in dandelion root have been found to encourage the release of toxins. Kelp has been found to protect the body from the absorption of toxic chemicals. Sodium alginate found in kelp protects the body from radiation exposure and heavy metal toxicity. It helps the body remove toxic waste.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=617) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
.jpg)
Turmeric is an herb which is a perennial plant included in the family of gingers. This plant is considered to be rhizomatous and has been found to be abundant in tropical countries such as South Asia. For its cultivation, this plant must grow in a climate with a temperature of 20 to 30 degrees Celsius and ample amount of yearly rain. In these kind of climates, this herb can grow healthy and abundantly. In some countries, an annual collection of Rhizomes is done and then reproduced and grown the next season. 
