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Advocacy Update   
Date:
May 17, 2008 10:17 AM
Recently, the Natural Products Association has experienced a flurry of activity on the legislative front. One month ago, Natural Products Association members went to Washington, D.C. to meet with their representatives and discuss legislation important to the association and the industry. Many who could not visit Washington in person were part of our "virtual march" on Washington that delivered e-mails, petitions, and videos to Congress on the importance of natural products. Natural Products Day was a great success, boasting higher than ever attendance at our evening Congressional reception, and resulting in additional co-sponsors for S. 771, the Child Nutrition Promotion and School Lunch Protection Act sponsored by Tom Harkin (D-Iowa). The bill now boasts co-sponsorship of more than a quarter of the Senate. Its companion bill in the House of Representatives, H.R. 1363, sponsored by Lynn Woolsey (D-Calif.), has gained an additional five co-sponsors as the result of Natural Products Day meetings and now has 140 co-sponsors. These bills continue to build momentum, thanks to your support. More recently, the Natural Products Association urged supporters to contact their legislators to include an amendment to the "Farm Bill" allowing food stamp recipients to purchase dietary supplements. This provision was similar to free-standing bills that have been introduced in the current and previous Congresses by Sens. Harkin and Orrin Hatch (R-Utah) and have earned the association's support. Although the amendment advanced further than other versions in previous sessions, it did not make the final Farm Bill, which was reported out of conference today. The good news is that the Farm Bill did contain significant increases in nutrition programs and increased funding for organic farming, another supported goal of the Natural Products Association. Because of the strong effort of our supporters on the amendment's behalf, the bill was placed on Congress's radar screens and has greatly improved the chances as stand-alone legislation, S. 770, the Food Stamp Vitamin and Mineral Improvement Act, of seeing passage. We will continue to ask for support on this important bill as this legislative session progresses. In addition, the Natural Products Association has been leading the fight to protect Dehydroepiandrosterone (DHEA), and to keep this important, safe, and effective supplement available to elderly consumers. The same players behind S. 762, which would wrongly classify DHEA as an anabolic steroid, proposed S. 2470 in late 2007 as a misplaced reaction the release of the Mitchell Report, which chronicled the abuse of steroids by professional baseball players. Although DHEA has no performance enhancing attributes, this bill was proposed to limit the access of minors to DHEA. The Natural Products Association and its supporters have worked hard to inform Congress of the benefits of DHEA, and that it is not an anabolic steroid and should not be classified as one. We have been able so far to prevent any movement on the bill, but the association continues to monitor its progress and make sure that this supplement remains accessible to the seniors who need it most. Thanks to your help, the Natural Products Association continues to have an active presence on Capitol Hill that is felt by legislators. We could not do it without the help of you, our supporters, who know how important it is to stand up for natural products. The impact of your messages to legislators continues to help the Natural Products Association to ensure all natural products - from natural and organic foods to dietary supplements and health and beauty aids - are accessible to Americans. With your continued support we will continue to be known as a vocal group with a wide base of support through the rest of this legislative session and beyond. To get involved, please visit our action center at www.capwiz.com/nnfa/issues/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1793) On Tuesday, April 8, the Natural Products Association - 11th Annual Natural Products Day 
Date:
April 10, 2008 04:46 PM
On Tuesday, April 8, the Natural Products Association and our sponsors will be hosting the 11th Annual Natural Products Day in Washington, D.C. This day is an important way for natural products advocates to reach out to Congress and discuss the issues that matter. For more information on Natural Products Day or to register, please visit www.NaturalProductsAssoc.org/npd08. Among the many healthy policies we’ll be asking members to promote on Capitol Hill, bill S. 770, Food Stamp Vitamin and Mineral Improvement Act, will be at the top of our list. S. 770 would give needy food stamp recipients the choice of purchasing certain vitamin and mineral supplements with their benefits, in the same way they are free to make other dietary choices. If the stamps can be used to buy a soda or snack cake, why not use them to buy a supplement to improve your health? These select supplements could improve appetite and growth rates in poor children; decrease infectious disease in the elderly; prevent neural tube birth defects; protect against heart disease and stroke; protect against some cancers; maintain cognitive function in the elderly; and build bone mass in the young and decrease bone loss in the old. But, you don’t have to go to the Hill to make a difference! If you can’t join us in Washington, D.C., you can still e-maiL your elected officials and tell them to support S. 770! Don’t miss this chance to put your stamp of approval on this important bill! Take Action Now!
Click here to e-mail your elected officials
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1749) At Last some good news concerning breast health!
Date:
February 23, 2006 03:33 PM
At last, some good news concerning breast health! Brevail is for women interested in maintaining optimal breast health. Perhaps you, like many woman, are concerned with the important issue of breast health. Annual mammograms, monthly self breast exams, escalating national statistics, or perhaps an unfortunate occurence in a loved one has raised awareness and concern in many of us. There is now reason for Optimism Brevail is the first all-natural product to address the maintenance of orderly cellular division in the preservation of healthy breast tissue. Research suggests that our bodies use natural plant lignans, now sparse in the modern diet, to sarely and gently buffer and balance potentially adverse effects of excess or toxic estrogens, established as the most well-known cause of certain breast problems. Estrogen left unchecked may result in rapid multiplication of breast cells, as well as inability for cells to repair potential mutations between cellular divisions. Body and Nature is balance Brevail was university researched and developed to increase lignan concentrations in the body to levels found in women who collectively demonstrate an extraordinary history of breast health. After only 48 hours of Brevail supplementation, women participating in a university based, oral pharmacokinetics study achieved lignan concentrations in plasma and urine equivalent to a reference group of women with a well-established history of extraordinary breast health. The results is a gentle return to balance between body and nature, just as nature intended. Hormonal Harmony In addition to the primary purpose of optimal breast health, many women have reported secondary benefits of brevail related to hormonal balance including improvements in pre and peri-menopausal, menopausal and post-menopausal discomforts. Further, many women have reported a greater sense of well-being associated to a reduction of stress and apprehension, and for taking a positive step toward a healthy future. Brevail has good news for you, a “window” of opportunity. The good news is a revolutionary new approach to breast health. Though a new approach, managing your “Estrogen window” is time honored, true, and scientifically established. Your lifetime exposure to estrogen is the most well-known risk factor for breast related health challenges. Your cumulative lifetime exposure to estrogens is referred to as your “Estrogen window.” Influences that increase and extend exposure to estrogen are said to “open” the window. Those that reduce or shorten exposure are said to “Close “ it. The wider and longer the window is left open, the greater your risk for breast related complications. Managing your estrogen window empowers you to choose a healthy future. Brevail is the first all-natural product designed to address the estrogen window by gently displacing excess or toxic estrogens. Adequate rest, exercise, a plant-based diet, and avoidance of alcohol are also ways to which you can consciously choose to manage your estrogen window toward a healthy future. Make a decision for health, life, and vitality! Proactive Breast Health is a monumental shift in thinking and action, away for passive resignation and toward proactive empowerment. The difference between fate and destiny is that you can plan your destiny in advance. Make a commintment to Brevail, and make a commitment to health, life, and vitality today. Brevail Philanthropy Brevail donates a percentage of all proceeds to the Breast Cancer Prevention Foundation, established to fund scientific and clinical research into breast cancer prevention, as well as to educate the public and medical community on proactive and preventative breast health measures, and for the purpose of outreach and support for women with breast cancer. Brevail, winner of two consecutive research grants Brevail was awarded an unprecedented two consecutive research grants from the Washington Technology Center, University of Washington, in the course of the 6-year span in which it was developed. Lignan Based strategies for Cancer Prevention was the topic and title of the grants.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1227) Folic Acid: Strengthening the Immune System in the Elderly
Date:
January 09, 2006 09:38 AM
Folic Acid: Strengthening the Immune System in the Elderly
By Greg Arnold, DC, CSCS, December 20, 2005, abstracted from “Dietary folate improves age-related decreases in lymphocyte function” in the January 2006 issue of the Journal of Nutritional Biochemistry Recent research has elucidated health-promoting roles for folic acid beyond that of insuring normal development of the fetus. In addition to helping decrease neural tube defects,1 folic acid can also help treat inflammatory bowel disease 2 improve memory 3 and help decrease an amino acid in the body, homocysteine,4 that increases heart disease risk.5 Now a new study 6 has found another way that folic acid can help us age more gracefully: by helping strengthen our immune system. Recognizing the importance of nutrition in the overall health of the immune system 7 and knowing that certain types of immune system cells, called “T cells”, decrease with age,(8,9) researchers fed 11-month-old and 23-month-old male rats either a control diet or a diet fortified with 35.7 mg per kg of folic acid for three weeks. Researchers found “a significant” increase in immune system strength in the folic acid group, specifically that of increased T cell levels, other immune system proteins called IL-2, IL-4, and anti-cancer proteins called “tumor necrosis factor”. While the study reaffirmed the immune system’s weakening with increasing age, the researchers concluded that “supplementing…with additional folate improves [immune system function] and that dietary folate requirement may be higher in the older population than in the younger population to support immune functions.” Greg Arnold is a Chiropractic Physician practicing in Danville, CA. You can contact Dr. Arnold directly by emailing him at mailto:ChiroDocPSUalum@msn.com or visiting his website www.CompleteChiropracticHealthcare.com Reference:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1179) Court Rules for FDA in Lane Labs Appeal
Date:
December 12, 2005 09:44 AM
A federal appeals court has ruled that Lane Labs (Allendale,NJ) may be ordered to pay back consumers for selling what the food and drug administration (FDA) considered unapproved new drugs. The three-judge panel upheld the 2004 decision by U.S. district Judge William G. Bassler of the District of New Jersey, which stated that FDA may demand that Lane Labs pay back every consumer who had bought the company’s top selling products—shark cartilage supplements that were allegedly marketed as treatments for diseases including cancer and HIV. The restitution amount is estimated at 109 million. The appeals court rejected the argument that FDA cannot demand restrictions because the Federal Food, Drug, & Cosmetic Act (FDCA) does not expressly provide for such a remedy. “Whether or not congress specifically contemplated restitution under the FDCA, the ability to order this remedy is within the broad equitable power granted to the district courts to further the economic protection purposes of the statute,” 3rd Circuit Judge Marjorie O. Rendell wrote in an opinion joined by Judges Maryanne Trump Barry and Edward R. Becker. In its appeal, Lane Labs was supported by an amicus brief from the Washington Legal Foundation (WLF, Washington, DC) urging the court to reverse Bassler’s decision, on the grounds that restitution is not authorized anywhere in the text of the FDCA. WLF attorneys Daniel J. Popeo and Richard A. Samp, joined by attorney Jeffrey A Lamken of Baker Botts in Washington, DC, argued that the FDCA gives courts the power to “restrain” violations, but does not allow FDA to seek “Backward-looking monetary relief.” WLF argued that FDA, throughout most of its history, never asserted a right to seek restitution until recently, when it began asserting that power in order to have “a big club with which to intimidate manufacturers who might otherwise seek to challenge FDA directives,” including large pharmaceutical companies. However, the court upheld FDA’s authority to seek restitution on the grounds that the FDCA’s grant of authority to restrain violations of the Act should be read broadly to include all forms of equitable relief. FDA cannot be allowed to get away with this power grab,” said Samp after reviewing the Third Circuit’s decision. “The American economy suffers, and public safety and health are jeopardized, when FDA seeks to exert power beyond its authority, upsetting to delicate balance struck by Congress in its attempt to both preserve the public welfare and encourage valuable pharmaceutical innovations.” He added that WLF has pledged to continue to litigate the issue and to support Lane Labs in any further appeals the company may file.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1011) Dr. Verghese, M.D. Liver Detoxifier & Regenerator Fact Sheet
Date:
December 07, 2005 12:16 PM
Dr. Verghese, M.D. Liver Detoxifier & Regenerator Fact Sheet Neil E. Levin, CCN, DANLA 02/10/05 LIKELY USERS: People with exposure to toxins that stimulate liver activity; People with exposure to infections that may have damaged liver tissue KEY INGREDIENT (S): Milk Thistle extract (Silymarin), Glutathione, NAC, Bupleurum extract, Grape Seed Extract, Dandelion Root extract, Artichoke Leaf, Schisandra and about a dozen additional herbs, along with synergistic ingredients MAIN PRODUCT FEATURES: This formula was developed by a physician based on his clinical experience.
Artichoke leaf has antioxidant properties and restores healthy growth to liver cells. Bupleurum may promote normal cell growth, immune function and is a staple of Chinese liver formulas. Dandelion Root may serve as a natural down-regulator of inflammatory chemicals in the body. NAC supports liver Glutathionestores (antioxidant, detoxifier, heavy metal chelator). Schisandra protects liver cells from toxins and may help to regenerate damaged cells. Milk thistle’s antioxidant Silymarin improves liver function tests and protects liver cells against oxidative damage. It also protects liver cells by blocking and removing toxins from the liver. Silymarin aids in regenerating injured liver cells and blocks fibrosis. OTHER IMPORTANT ISSUES: Samuel Verghese, M.D. (AM), Ph.D., BCIA-EEG, DAAPM, holds a degree in Alternative Medicine and specializes in Nutritional, Ayurvedic and other Alternative Health Solutions. He is certified as a BCIA-EEG Associate Fellow. AMOUNT TO USE: Three or more capsules a day, preferably with meals. COMPLEMENTARY PRODUCTS: Antioxidants (supports liver detoxification), Alpha Lipoic Acid, EGCg Green Tea Extract, Astragalus, medicinal mushrooms (shiitake, reishi), SAM-e (may improve bile flow and promotes methylation to detoxify chemicals), TMG, lecithin, thymus glandular extract, Cordyceps. AVOID: acetaminophen, alcohol, iron supplements (also red meat, fortified flour) CAUTIONS: This formula should not be used by pregnant women, nursing mothers children or those with liver problems unless recommended under the supervision of a healthcare professional. Please notify your physician about your supplement use if you are using any drugs! Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. REFERENCES:
1. Salmi HA, Sarna S. Effect of silymarin on chemical, functional and morphological alterations of the liver. A double-blind controlled study. Scand J Gastroenterol 1982;17:517–21.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=980) Trace Minerals and Migraines
Date:
November 16, 2005 12:02 PM
Trace Minerals and Migraines An increasingly large amount of disease today may be attributable to deficiencies in the supply of trace minerals in our diets.1 How can this be the case when the availability of food in our country is unprecedented, with a supermarket on every corner? These deficiencies do not stem from a lack of quantity of food, rather they stem from the quality of food. Trace minerals can be found mainly in whole, unprocessed foods such as vegetables and fruits. Unfortunately, the large majority of fruits and vegetables found in supermarkets today are nutritionally devoid of these minerals, largely in part to the high-yield farming practices in this and other countries. The mineral content of food is mainly dependent on the amount of minerals found in the soil in which it is grown. Current farming practices leave soils with less than optimal amounts of these minerals, especially the less common trace minerals. As a result of this, our food supplies leave us at risk for deficiencies of these very important substances. Because of this situation, it is essential that every person now supplement their diet with trace minerals in order to avoid the many diseases that are attributable to this scarcity. A lack of vital nutrients leaves the body unable to function fully, leaving it vulnerable to disease. Trace minerals have numerous roles. Oftentimes, because these minerals are found in such small quantities in the body, scientists and physicians have paid little attention to their importance in health and disease prevention. However, with the advent of improved science and the recognition of the efficacy of natural medicine, we are beginning to understand how vital these elements are to our health. Trace minerals, in a sense, are akin to the numerous tiny nails, nuts, and bolts that hold a house together. At first glance, a home is made of much more than these items. However, if they are slowly removed and never replaced, the house will continue to sag and finally fall apart. So it is the same with the smallest building blocks of our bodies. Trace minerals are important in the proper functioning of enzyme systems, nerve conduction and muscle function, assisting with transfer of nourishment into cells, providing the framework for tissues, and regulation of organ functions. These ‘behind the scenes’ functions are not possible without a constant, adequate supply of minerals. Even with the many multivitamin and mineral supplements available, most of these products fall short because they do not contain large enough amounts of the trace minerals that are so important to health. Physicians that specialize in natural medicine are some of the biggest proponents of trace mineral supplementation. This type of physician is attuned to the many subtleties of the functions of the human body, and oftentimes addresses health issues with nutritional therapeutics in an attempt to bring the body’s health back into balance. This process of balance, also known as homeostasis, occurs quite wonderfully all by itself, as long as the body has the proper fuel and building materials. Unfortunately, physicians are seeing more and more diseases, which can be attributed to the body’s inability to achieve this balance. This trend towards ill health is directly related to the dearth of nutritional value in our diets today. However, practitioners of natural medicine are very excited with the many dramatic turn-arounds toward health that many of their patients have experienced with the use of mineral supplementation. A common example of this is the treatment of migraine headaches with magnesium. Recent statistics suggest that 18 percent of women and six percent of men suffer from migraine and those numbers are increasing.2 The Centers for Disease Control reported a 60-percent increase in the disease from 1980 to 1989.3 Migraine headaches occur when the blood vessels in the brain spasm and constrict. Soon after this constriction occurs, the blood vessels then reflexively open, or dilate. When the vessels become dilated, they occupy more space in the brain, activating nearby pain receptors. It is speculated that an imbalance of mineral stores in the body can lead to this spasm of the blood vessels. Many researchers have suggested magnesium plays an important role in migraine attacks. The activities of magnesium in the body include preventing blood vessel spasm, inhibiting blood clotting, and stabilizing cell membranes, all of which are involved in migraine develoment4. Magnesium concentration exerts an effect on neurotransmitter production and receptors, pro-inflammatory molecules, and other migraine-related chemicals in the brain.5 Recent evidence suggests up to 50 percent of migraine patients have lowered levels of tissue magnesium during an acute migraine attack.6 Another study discovered brain magnesium concentrations were 19 percent lower in patients during migraine attack compared to healthy controls.7 Because recent research strongly indicates a magnesium deficiency in migraine headaches, natural medicine practitioners prescribe magnesium along with other trace minerals as a primary treatment for this condition with great success. Because of their widespread distribution throughout the metabolic workings of the human body, trace minerals are integral to the functioning of one of the body’s largest organ systems, the muscles. Mainly, magnesium plays a large role in the relaxation of muscles following their contraction. Without this vital nutrient, it would be impossible for the muscles of the human body to function. Muscle cramps are prevalent in western society due to lack of intake of an appropriate amount of minerals. One easy, straightforward cure for muscle cramping is supplementation with magnesium and other trace minerals, as they allow the muscles to function smoothly and correctly. The role of magnesium in relieving cramped muscles also makes it a highly appropriate therapy for the muscle pain associated with fibromyalgia, a condition that is often treated successfully by practitioners of natural medicine. These practitioners often use high doses of magnesium and other trace mineral combinations to reduce the painful and tender muscles that are so common in fibromyalgia patients. Another condition that is successfully treated with magnesium and trace minerals is Chronic Fatigue Syndrome. People with this condition often experience profound muscle aches and weakness. It has been shown that in order for proper muscle contraction and relaxation to occur, magnesium and calcium need to be present in proper amounts in the body, which can be difficult to achieve even on a standard healthy diet. Additionally, magnesium and mineral supplementation may decrease the pain involved with sports-related injuries and excessive physical activity. As we use our muscular system, it is slowly depleted of these minerals, making replacement a top priority. Others signs of magnesium deficiency include disorientation, depression, tingling, numbness, seizures, abnormal heart rhythms in addition to muscle spasms and cramps.8,9 A minimum of at least 60 trace minerals has been demonstrated to be vital to health and well-being.10 This article has covered only a small fraction of the multitudes of health benefits of trace minerals. As science and natural medicine continues to uncover the many roles for all of these trace minerals, doctors are finding exciting solutions to several maladies that may be successfully treated by replacing these nutrients in the body. Unless we begin replacing these minerals early on in life, we put ourselves at risk for the many diseases of mineral deficiency that are becoming more and more prevalent in society today. References: -------------------------------------------------------------------------------- 1 Medical Nutrition from Marz, 2nd Edition. Omni-Press, 1997. Pps. 103-107 2 Stewart WF, Lipton RB, Celentano DD, et al. Prevalence of migraine headache in the United States: relation to age, income, race, and other sociodemographic factors. JAMA 1992;267:64-69. 3 Rappaport AM, Scheftell FD. Headache Disorders: A Management Guide for Practitioners. Philadelphia, PA: WB Saunders Co.;1996:4. 4 McCarty MF. Magnesium taurate and fish oil for prevention of migraine. Med Hypotheses 1996;47:461-466. 5Sinclair, S. Migraine Headaches: Nutritional, Botanical And Other Alternative Approaches. Alternative Medicine Review - Volume 4, Number 2, April 1999. 6 Mauskop A, Altura BM. Role of magnesium in the pathogenesis and treatment of migraine. Clin Neurosci 1998;5:24-27. 7 Ramadan NM, Halvorson H, Vande-Linde A, et al. Low brain magnesium in migraine. Headache 1989;29:590-593. 8 Rude RK. Magnesium deficiency: A cause of heterogeneous disease in humans. J Bone Miner Res 1998;13:749-58. 9 Institute of Medicine. Food and Nutrition Board. Dietary Reference Intakes: Calcium, Phosphorus, Magnesium, Vitamin D and Fluoride. National Academy Press. Washington, DC, 1999.
10 Kelly, GS. Sports Nutrition: A Review of Selected Nutritional Supplements For Bodybuilders and Strength Athletes-Alternative Medicine Review - Volume 2, Number 3, May 1997
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=941) The Heart Disease - Pollution Connection
Date:
July 07, 2005 05:04 PM
Heart disease isn't the illness we usually associate with the health hazard known as pollution, but perhaps it should be. While pollution is strongly (and rightly) linked to cancer in the public mind, officials now realize that airborne junk can gum up the circulatory system. They've even coined a term for it: environmental cardiology. The main villain is fine particulate matter, present in factory and vehicle emissions. These particals are so small they sift right through the lungs and into the bloodstream. There, fine particulate ignites inflammation, accelerates arterial narrowing, thickens blood and disrupts the heart's pacemaking mechanism. Other airborne pollutants hazardous to the heart include carbon monoxide and sulfur dioxide. As young as it is, environmental cardiology has already taken some interesting turns. At least 17 of 87 government-monitored water contaminants have been linked to cardiovascular disease. Even more intriguing is the theory that pollution may wreak heart disease during adulthood. After years on the research fringe, environmental cardiology moved to center stage with the publication of its own American Heart Association Scientific Statement, which concluded the air pollution poses as "Serious public health problem" in terms of heart disease. A pronouncement from such a mainline health group has translated into big bucks for studies. The biggest so far: a $30 Million, 10-year effort, led by the University of Washington, that will evaluate roughly 8700 people for signs of pollution sparked cardiovascular illness. No one is discounting such traditional heart risk factors as poor diet and insufficient exercise. But the air we breathe is making many of our hearts sick and it's about time big medicine started sitting up and taking notice. --Lisa James....
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=562) REFERENCES
Date:
June 25, 2005 08:13 PM
REFERENCES 1 a. The Surgeon General’s “Nutrition and Health Report.” b. The Centers for Disease Control and Prevention’s “National Health and Examination Survey (NHANES III)” c. The National Academy of Science’s. Diet and Health Report: Health Promotion and Disease Objectives (DHHS Publication No. (PHS) 91-50213, Washington, DC: US Government Printing Office, 1990). e. Dietary Guidelines for Americans. 2 Rolls BJ. Carbohydrates, fats, and satiety. Am J Clin Nutr 1995; 61(4 Suppl):960S-967S. 3 McDowell MA, Briefel RR, Alaimo K, et al. Energy and macronutrient intakes of persons ages 2 months and over in the United States: Third National Health and Nutrition Examination Survey, Phase 1:1988-91. Advance data from vital and health statistics of the Centers for Disease Control and Prevention; No. 255. Hyattsville, Maryland: National Center for Health Statistics; 1994. 4 Center for Science in the Public Interest and McDonald’s Nutrition and You—A guide to Healthy Eating at McDonald’s: McDonald’s Corp,1991. 5 Bray GA. Appetite Control in Adults. In: Fernstrom JD, Miller GD eds. Appetite and Body Weight Regulation. Boca Raton: CRC Press, 1994:1-92. 6 Michnovicz JJ. How to Reduce Your Risk of Breast Cancer. New York: Warner Book Inc. 1994:54. 7 Carcinogens and Anticarcinogens in the Human Diet. National Research Council Report, National Academy of Sciences, 15 Feb. 1996. 8 Van Tallie TB. Obesity: adverse effects on health and longevity. Am J Clin Nutr 1979:32: 2723-33. 9 Somer E, M.A. R.D. Nutrition for Women. New York: Henry Hold and Company, 1993:273. 10 Swaneck GE, Fishman J. Covalent binding of the endogenous estrogen 16A-hydroxyestrone to estradiol in human breast concer cells: characterization and intranuclear localization. Proc Natl Acad Sci USA 1988:85;7831-5. 11 Colditz GA. Epidemiology of breast cancer. Findings from the nurses’ health study. Cancer1993;714:1480-9. 12 Hennen WJ. Breast Cancer Risk Reduction. The effects of supplementation with dietary indoles. Unpublished report 1992. 13 Deslypere BJ. Obesity and cancer. Metabolism 1995;44(93):24-7. 14 Somer E, M.A. R.D. Nutrition for Women. New York: Henry Hold and Company, 1993:281. 15 Whittemore AS, Kolonel LN, John M. Prostate cancer in relation to diet, physical activity, and body size in blacks, whites, and Asians in the United States and Canada. J Natl Cancer Inst 1995;87(9):629-31. 16 Key T. Risk factors for prostate cancer. Cancer Survivor 1995;23:63- 77. 17 Kondo Y, Homma Y, Aso Y, Kakizoe T. Promotional effects of twogeneration exposure to a high-fat diet on prostate carcinogenisis in ACI/Seg mice. Cancer Res 1994;54(23):6129-32. 18 Wang Y, Corr JG, Taler HT, Tao Y, Fair WR, Heston WD. Decreased growth of established human prostate LNCaP tumors in nude mice fed a low-fat diet. J Natl Cancer Inst. 1995;87(19):1456-62. 19 Nixon DW. Cancer prevention clinical trials. In-Vivo 1994;8(5):713-6. 20 Key T. Micronutrients and cancer aetiology: the epidmiological evidence. Proceed Nutr Soc 1994;53(3):605-14. 21 Gorbach SL, Goldin BR. The intestinal microflora and the colon cancer connection. Reviews of Infectious Diseases 1990;12(Suppl 2):S252-61. 22 Shrapnel WS, Calvert GD, Nestel PJ, Truswell AS. Diet and coronary heart disease. The National Heart Foundation of Australia. Med J Australia. 1995;156(Suppl):S9-S16. 23 Ellis JL, Campos-Outcalt D. Cardiovascular disease risk factors in native Americans: a literature review. Am. J. Preventive Med 1994;10(5):295-307. 24 DiBianco R. The changing syndrome of heart failure: an annotated review as we approach the 21st century. J. Hypertension 1994; 12(4 Suppl):S73- S87. 25 Van Itallie TB. Obesity: adverse effects on health and longevity. Am J Clin Nutr 1979;32(suppl):2723-33. 26 Kestin M, Moss R, Clifton PM, Nestel PJ. Comparative effects of three cereal brans on plasma lipids, blood pressure and glucose metabolism in mildly hyper-cholesterolemic men. Am J Clin Nutr 1990;52(4):661-6. 27 Story JA. Dietary fiber and lipid metabolism. In: Spiller GA, Kay RM. eds. Medical Aspects of Dietary Fiber. Penun Medical; New York, 1980, p.138. 28 Stein PP, Black HR. The role of diet in the genesis and treatment of hypertension. Med. Clin. North America. 1993;77(4):831-47. 29 Olin JW. Antihypertensive treatment in patients with peripheral vascular disease. Cleve. Clin. J. Medicine. 1994;61(5):337-44. 30 Tinker LF. Diabetes Mellitus—a priority health care issue for women. J. Am. Dietetic Association. 1994;94(9):976-85. 31 Gaspard UJ, Gottal JM, van den Brule FA. Postmenopausal changes of lipid and glucose metabolism: a review of their main aspects. Maturitas. 1995;21(3):71-8. 32 Coordt MC, Ruhe RC, McDonald RB. Aging and insulin secretion. Proc. Soc. Exp. Biology and Medicine. 1995;209(3):213-22. 33 Felber JP. From Obesity to Diabetes. Pathophysiological Considerations. Int. Journal of Obesity 1992;16:937-952. 34 Gillum RF. The association of body fat distribution with hypertension, hypertensive heart disease, coronary heart disease, diabetes, and cardiovascular risk factors in men and women age 18-79. J Chronic Diseases 1987;40:421-8. 35 Haffner SM, Stern MP, Hazuda HP, et al. Role of obesity and fat distribution in non-insulin-dependent diabetes mellits in Mexican Americans and non- Hispanic whites. Diabetes Care 1986;9:153-61. 36 Bonadonna RC, deFronzo RA. Glucose metabolism in obesity and type 2 diabetes. Diabetes and Metabolism. 1991;17(1 Pt. 2):12-35. 37 Shoemaker JK, Bonen A. Vascular actions of insulin in health and disease. Canadian J. of Applied Physiology. 1995;20(2):127-54. 38 Resnick LM. Ionic Basis of Hypertension, Insulin Resistaince, Vascular Disease, and Related Disorders. The Mechanism of ‘Syndrome X’. Am. J. Hypertension. 1993;6(suppl):123S-134S. 39 Trautwein EA. Dietetic influences on the formation and prevention of cholesterol gallstones. Z. Ernahrugswiss. 1994;33(1):2-15. 40 Cicuttini FM, Spector TD. Osteoarthritis in the aged. Epidemiological issues and optimal management. Drugs and Aging. 1995;6(5):409-20. 41 Melnyk MG, Wienstein E. Preventing obesity in black women by targeting adolescents: a literature review. J Am. Diet. Association. 1994;94(4):536-40. 42 Robinson BE, Gjerdingen Dk, Houge DR. Obesity: a move from traditional to more patient-oriented management. J. Am. Board of Family Practice. 1995;8(2):99-108. 43 Dulloo AG, Miller DS. Reversal of Obesity in the Genetically Obese fa/fa Zucker Rat with an Ehpedrine/Methylxanthines Thermogenic Mixture. J. Nutrition. 1987;117:383-9. 44 Dulloo AG, Miller DS. The thermogenic properties of ephedrin/methylxanthine mixtures: animal studies. Am J Clinical Nutr. 1986;43:388-394. 45 Richelsen B. Health risks of obesity. Significance of the regional distri-bution of adipose tissue. Ugeskr. 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Academic Press, Inc. 1984. 76 Abelin J and Lassus A. Fat binder as a weight reducer in patients with moderate obesity. ARS Medicina, Helsinki, Aug- October, 1994. 77 Kanauchi O, Deuchi K, Imasato Y, Shizukuishi M, Kobayashi E. Increasing effect of a Chitosan and ascorbic acid mixture on fecal dietary fat excretion. Biosci Biotech Biochem 1994;58(9):1617-20. 78 Maezaki Y, Tsuji K, Nakagawa Y, et al. Hypocholesterolemic effect of Chitosan in adult males. Biosci Biotchnol Biochem1993;57(9):1439-44. 79 Kobayashi T, Otsuka S, Yugari Y. Effect of Chitosan on serum and liver cholesterol levels in cholesterol-fed rats. Nutritional Rep. Int., 1979;19(3):327-34. 80 Sugano M, Fujikawa T, Hiratsuji Y, Hasegawa Y. Hypocholesterolemic effects of Chitosan in cholesterol-fed rats. Nutr Rep. Int. 1978;18(5):531-7. 81 Vahouny G, Satchanandam S, Cassidy M, Lightfoot F, Furda I. Comparative effects of Chitosan and cholestryramine on lymphatic absorption of lipids in the rat. Am J Clin Nutr, 1983;38(2):278-84 82 Suzuki S, Suzuki M, Katayama H. Chitin and Chitosan oligomers as hypolipemics and formulations containing them. Jpn. Kokai Tokkyo Koho JP 63 41,422 [88,422] 22 Feb1988. 83 Ikeda I, Tomari Y, Sugano M. Interrelated effects of dietary fiber on lymphatic cholesterol and triglyceride absorption in rats. J Nutr 1989;119(10):1383- 7. 84 LeHoux JG and Grondin F. Some effects of Chitosan on liver function in the rat. Endocrinology. 1993;132(3):1078-84. 85 Fradet G, Brister S, Mulder D, Lough J, Averbach BL. “Evaluation of Chitosan as a New Hemostatic Agent: In Vitro and In Vivo Experiments In Chitin in Nature and Technology. Eds: R Muzzarelli, C Jeuniaux, GW Gooday. Plenum Press, New York. 1986. 86 Malette W, Quigley H, Gaines R, Johnson N, Rainer WG. Chitosan A New Hemostatic. Annals of Thorasic Surgery. 1983;36:55. 87 Malette W, Quigley H, Adickes ED. Chitosan effect in Vascular Surgery, Tissue Culture and Tissue Regeneration. 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(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=507) SUMMARY
Date:
June 25, 2005 10:21 AM
SUMMARY In 1990, the First World Congress on the Health Significance of Garlic and Garlic Constituents was held in Washington, D.C. Forty-six presentations were heard by fifty scientists on the health benefits of garlic. Topics addressed included garlic’s ability to fight infection, especially Candida albicans, and to prevent cardiovascular disease and cancer. Finally, ancient medicinal practices regarding garlic are being vindicated by twentieth-century scientists who, for a long period of time, literally turned up their noses at the prospect of garlic as a viable therapeutic agent. Today, both scientific and herbalist tradition support the fact that garlic, in its various forms can provide extraordinary health benefits. Unquestionably, it can significantly reduce the risk of cardiovascular disease and certain kinds of cancer. Taking garlic in certain dosages can help protect human cells from oxidation, free radicals and certain types of radiation. Garlic is an effective immune system booster and has anti-bacterial, anti-viral and anti-fungal properties. Garlic promises to emerge once again, as a powerful medicinal agent which will most certainly impact 21st-century health practices.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=442) Breathe Easy
Date:
June 14, 2005 06:19 PM
Breathe Easy by Edward Bullard, III Energy Times, March 1, 1998 Don't underestimate the danger of asthma. When an asthmatic attack chokes the passageways to your lungs, cutting off your air supply, the consequences can prove frightening and disastrous. Although asthma is the leading chronic illness among children, most sufferers are adults. The condition ranks as the 7th most common chronic affliction nationwide affecting 14 to 20 million people; about 11 million of these are over the age of 18. The American Lung Association estimates that between 1982 and 1992 the total number of asthma cases jumped by more than 57%. Researchers can't pinpoint the reasons for this rise, but they have found that urban dwellers suffer a higher asthma risk. Despite the gloomy statistics, those who suffer asthma can take reassurance from the progressive development of complementary and conventional treatments that control this condition. Anyone who suffers asthma should consult with a knowledgeable health practitioner. How does asthma start? This airway problem may originate with allergies and sinus or bronchial infections (the bronchi are the tubes leading to the lungs). Some experts believe that air pollution, dust mites, cockroach remains and other environmental toxins may exacerbate the condition. A family history of allergies and asthma also increases your asthmatic vulnerability since your genes may make you more prone to the airway inflammation that leads to breathing constraints. Allergic reactions to food have been implicated in causing restricted breathing. Food found to most frequently instigate immediate lung difficulties include nuts, peanuts (which are, technically, legumes not nuts), eggs, shellfish and fish. Foods that do not cause immediate wheezing but may produce a delayed respiratory effect include artificial food colorings, wheat, citrus fruits, milk, chocolate and wheat products. Since an allergic reaction to particular foods can apparently play a role in asthma, some people find relief by systematically eliminating foods from their diets, identifying troublesome items and then permanently avoiding those foods. Asthma's Nutrition Gap According to Richard N. Firshein, D.O., director of the Firshein Center for Comprehensive Medicine in New York City, asthma stems from cells' "disordered metabolism." In these circumstances, the body's immune system often mistakes allergens (normally benign substances) for infectious agents. In strenuously defending itself against allergens, the body goes on "red alert," says Dr. Firshein in his book Reversing Asthma (Warner), "exhausting itself in the process." This creates a need for extra vitamins, minerals and other nutrients. Too often, he believes, this nutritional need is not met and asthma ensues. In the presence of asthma, magnesium can help restore free breathing. Dr. Firshein reports that about 50 years ago, medical researchers discovered that treating asthma victims with magnesium sulfate opened up breathing passageways. Although magnesium by itself does not completely alleviate asthma attacks, many emergency room doctors still use it in conjunction with other treatments to restore breathing. In explaining magnesium's usefulness in alleviating asthma, Dr. Firshein notes that magnesium competes with calcium in each cell to influence asthmatic reactions. For instance, calcium stimulates mast cells (reactive immune cells) to release histamine, a chemical that foments allergic reactions that hinder breathing. Conversely, magnesium "stabilizes" mast cells, quieting their activity so that they retain their histamine instead of flooding breathing passages. In addition, calcium takes part in muscle contractions that can constrict breathing tube muscles. Magnesium can help relax those same muscles. Although intravenous treatment with magnesium for acute asthma attacks must be carried out by a trained health professional, taking magnesium supplements over a period of time, may gradually help assuage asthma's wheezes. How do you tell if you're short of magnesium? Standard blood tests of magnesium levels may be inadequate. As Dr. Firshein points out, normal blood tests only examine the amount of magnesium floating in the blood's plasma. That level can apparently appear sufficient even if red blood cells are magnesium-deficient. (Dr. Firshein recommends asking your health practitioner for a special red blood cell test.) Ephedra for Asthma Ever since about 3,000 BC, Chinese health practitioners have been giving the herb ma huang (Ephedra sinica) to asthma sufferers. In the 1920s, western medical researchers extracted a chemical called ephedrine from ma huang and soon synthesized this substance for use as a pharmaceutical. However, herbal experts believe that there are other beneficial substances in ma huang besides ephedrine that can ease breathing. Although ephedra has been used successfully to ward off the allergies of hayfever as well as mild asthma, when this herb is taken over a long period its benefits may lessen. The reason: eventually the herb's ephedrine weakens the adrenal glands, according to Michael Murray, ND, and Joseph Pizzorno, ND, in the Encyclopedia of Natural Medicine (Prima). To offset this effect, they recommend supporting the use of ephedra with licorice (Glycerrhiza glabra) as well as ginseng (Panax ginseng) which support the adrenals. In addition, vitamins C and B6 and zinc and magnesium plus pantothenic acid also boost adrenal function. Licking Asthma with Licorice Since much of asthma's deleterious effects on health stem from the fact it inflames breathing passageways, licorice root, which acts to squelch inflammation and which calms allergies, can be helpful in restoring normal breathing. Licorice, according to Drs. Murray and Pizzorno, promulgates the persistence of cortisol in our body, a hormone that acts as an anti-inflammatory agent. As an extra benefit, licorice can also forestall the side effects of cortisone, one of the most widely prescribed medicines for asthma. Licorice also boosts cortisone's desirable anti-inflammatory action while inhibiting the action of enzymes that would otherwise increase unwanted inflammation. Onions + Garlic = Better Breath Despite their reputation for giving you bad breath, both onion and garlic can improve the breath of those afflicted with asthma. The reason: both of these plants restrict the action of an enzyme with the tongue twisting name of lipoxygenase, a chemical that helps produce inflammation. Studies with animals showed that when they were fed onion extract, their induced asthmatic problems decreased. Part of onion's benefit may be due to its quercetin content. (Quercetin is a bioflavonoid available as a supplement.) Onion also contains mustard oils, which are believed to slow the body's production of leukotrienes (substances that also increase inflammation). Vitamin C Vitamin C, the most abundant antioxidant nutrient in the lungs' inner lining, apparently protects against respiratory problems. Studies of people with asthma show that they possess less vitamin C both in their circulating blood and in white blood cells. When researchers induced bronchial constriction in people who volunteered for respiratory studies, they found that those given vitamin C didn't have as hard a time breathing. Experts recommend healthy doses of vitamin C plus other antioxidant nutrients such as vitamin E, carotenoids and selenium to lower the risk of allergic reactions and ease breathing. Antioxidant nutrients restrict the action of free radicals, molecules that attack the lungs and other parts of the cardiovascular system. Chinese skullcap (Scutellaria baicalensis) also effectively fights inflammation without causing serious side effects. Experts believe its bioflavonoids stop the body from making biochemicals that inflame tissues. Aside from restricting inflammation, these bioflavonoids also act as antioxidants. Strength in Numbers
Asthma support organizations can provide vital information: Organizations American Lung Association 1740 Broadway, New York, NY 10019-43741 (800) LUNG-USA llergy & Asthma Network/Mothers of Asthmatics Inc., 3554 Chain Bridge Road, Suite 200, Fairfax, VA 22030 (703) 385-4403, (800) 878-4403 th/aanma Asthma and Allergy Foundation of America,1125 15th Street, N.W., Suite 502 Washington, DC 20005 (800) 727-8462
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=361) Marilu Henner: Energy Personified!
Date:
June 14, 2005 11:50 AM
Marilu Henner: Energy Personified! by Stephen Hanks Energy Times, January 3, 2005 Marilu Henner is an actress, dancer and author, a health, fitness and cooking guru and a devoted mom. Now she's also an advocate for nutritional supplements. In this revealing interview, she offers her thoughts on the battle to support consumer rights and to create a better health care system in America. "So, you want to know what my schedule is after I finish talking with you?" Marilu Henner says, in an almost breathless voice. "Today's Tuesday, right? Tomorrow morning I leave Los Angeles [where she lives] for New York City so I can do the Tony Danza Show first thing Thursday morning, Then, I take a 9 am flight back to LA because my son has a sleepover birthday party. I have a 7 am flight to New Jersey the next morning because I'm speaking about mental health at a conference at a big country club. The next morning, I catch a 7 am flight back to LA for my son's soccer games, one at noon and the other at 2. Whew!" Trying to keep up with Marilu Henner would make anybody feel out of breath because the woman is energy personified. At 52, her schedule includes acting in movies, on television and in the occasional Broadway show, writing books (she's authored seven, including Total Health Makeover and Healthy Life Kitchen), teaching online diet and exercise classes through her website (marilu.com), taking Pilates classes three times a week and raising two sons, Nicholas (10) and Joseph (8). But now, on top of all that, the former star of the TV show Taxi has become a health and nutrition activist, speaking out in favor of the use of dietary supplements whenever she can. This past September, Henner testified at a hearing of the House Subcommittee for Human Rights and Wellness to advocate increased funding for research and full implementation of the Dietary Supplement Health and Education Act (DSHEA). During her testimony, Marilu described why she believes consumers should have access to more information about supplements and why the products should be made more accessible through both government initiatives and private health plans. "I believe that dietary supplements should be part of a campaign to improve our nation's health," Henner testified. Energy Times recently caught up with Marilu at her Los Angeles home for a freewheeling conversation. Here, this vibrant yet down-to-earth celebrity displays her passion for health, nutrition and consumer issues. Energy Times: You've become one of the most high profile celebrities to advocate a consumer's use of dietary supplements. What was your motivation to get involved in such a public way? Marilu Henner: As a teenager, I had been a yo-yo dieter. I could be around 135 pounds and balloon up to 174. I knew I needed a different way of looking at my life. I couldn't concentrate on those stupid diets where I could lose 20 pounds in a week and then gain it all back over a weekend. But after my mom died at 58 in 1978, I said to myself, "It's not really about my body anymore, it's really about my health." I just became obsessed with health. I read everything I could get my hands on. I starting taking human anatomy classes, going to medical libraries and seeing nutritionists and doctors. And I started experimenting on myself, turning myself into my own guinea pig. It took me about eight years to put together a program. I always say that my health birthday was 1979, but it wasn't until 1987 that I could say I was living a completely healthy lifestyle. ET: Were you ever really heavy when you were performing in a show? MH: Sure. When I first performed the role of Marty in "Grease" more than 30 years ago I weighed about 175 pounds. But I hid it well. When you wear those 1950s clothes you can get away with it. ET: When did you start incorporating supplements into your health program? MH: Before I became pregnant with my first son in 1993, I had never been a supplement taker. But I started taking prenatal vitamins and dietary supplements when I was breastfeeding and they made me feel really good. After the pregnancy, I just kept taking them because I was getting the essential nutrients that I couldn't get from food alone. I was getting great stuff from my food, but with all the travel I do-you know, the eating on planes and in restaurants-I couldn't always shop for organic food. I had a doctor who understood the value of dietary supplements and encouraged me to use them. I've taken them ever since and I recommend them to my family and friends, as well as to people through my books and classes. ET: What supplements other than vitamins do you find helpful in your total nutrition program? MH: I take vitamin E, omega-3 fish oils, antioxidants, garlic, coral calcium and echinacea supplements. ET: So let's get back to why you decided to testify before Congress in support of supplement use. MH: I know that as soon as you put a celebrity face on an issue, people tend to pay a little more attention. When I was in Washington, I was able to tell Congress the personal stories I've heard about people who turned their lives around-from debilitating illness to vibrant health-when they got the information they need to make good choices. By good choices, I mean rejecting the manufactured foods of our society, with their over-reliance on sugar, meat and dairy, and the chemicals, hormones and steroids that usually accompany these products. Instead, we should be moving towards an organic, vegan diet that produces a sense of physical health. I also believe that a healthy diet includes the use of appropriate dietary supplements. ET: Do you think that government is moving fast enough to reduce the restrictions on safe supplements? MH: Things could always move faster. But I remember years ago writing letters on behalf of people who wanted supplements without needing a prescription. When I would tell people about the benefits of soy products or supplements, they'd think I was nuts. Now those ideas are mainstream. The floodgates are open and people want to know more. You can't even keep up with all the information. I think that the government knows they're not going to get away with making people have a prescription to take their vitamins. ET: What is the citizen's responsibility in all this? MH: We're in a real transitional phase and people should take responsibility to educate themselves. You have to question your doctors and recognize when something is or isn't working. You have to find a health practitioner who really knows their stuff. ET: As you said, there's so much information out there, how do you decipher it all? How can someone be an educated information consumer? MH: I know it's very difficult because there are so many options. Believe me, I've been doing this a long time and I'm glad I did the research. I think you have to read everything. You have to find a nutritionist/herbalist/doctor who's the real deal and knows what they're talking about. You have to recognize the symptoms in your own body and try to figure it out. I think if you start out with a good multivitamin, a calcium supplement, fish oils and vitamin E, that can be your base and you can't go wrong. ET: Isn't a diet built on buying organic foods much more expensive? MH: Sure, it's a little more expensive. But there's nothing more expensive than bad health. There's nothing more expensive than food being thrown away because it doesn't taste right. Organic fruit tastes so much better than the perfect-looking fruits and vegetables sprayed with pesticides. ET: What's your advice to people who want to start a workout and weight-loss program? MH: I'm always saying to people, "Look, you walk your dog, your cat stretches, your hamster runs on a hamster wheel. You're an animal, too, so go move, go do something." I know a lot of people believe that when you want to lose weight you have to go on these 1,200-calorie-per-day diets. Well, my weight is always between 120-124 pounds and I eat close to 2,000 calories a day, but everything I eat is of quality. And I burn a lot of calories because I wear comfortable shoes and I move around in my life. I'm always strong, I never get sick and I feel like an animal. ET: How do you view the future of healthcare policy in this country and where do you think nutritional supplements fit in? MH: I strongly believe that the general public needs more access to dietary supplements to maintain essential good health. American research and development has come up with really great products, but the American Medical Association and the drug companies have stigmatized supplements. So what's the result? Most Americans don't have access to safe supplements because they are not covered by their health plans, nor recognized as effective by the federal government. This really needs to be changed. I think we should take 90% of what we're spending on drugs that barely keep people alive and start spending it on prevention, nutrition and changing lifestyle habits. In this country we're all about curing the disease rather than curing the patient. We don't look at the patient holistically and try to find out how the disease developed. Your doctor should be in charge of keeping you well, not keeping you in that strange state of, what I call, "dis-ease." It's like the medical and pharmaceutical establishment wants to keep you just sick enough so you'll continue to be a paying customer. They've convinced people to think they've got to take a pill to cure themselves rather than use their own bodies. ET: Do you think medical schools will start training doctors to treat patients holistically and focus more on preventative medicine? MH: I think we're seeing a lot more nutrition and alternative medicine specialists these days. And the general public is becoming more aware of health and nutrition issues then they were years ago. There's this groundswell of people saying "Wait, I need more information. Wait, my doctor's no longer God. I can't just keep taking these pills and trying to figure out all these warning labels and side effects." ET: Do you plan on becoming more politically active on these issues? MH: Absolutely, I want to work with any organization that wants to improve school lunch programs, improve the healthcare system and get people more involved in understanding nutrition and disease prevention.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=346) Battle Fatigue! Don't passively accept chronic exhaustion and weakness.
Date:
June 10, 2005 10:06 PM
Battle Fatigue! Don't passively accept chronic exhaustion and weakness. by Joanne Gallo Energy Times, December 6, 1999 Most folks wouldn't seek the distressing distinction of suffering chronic fatigue syndrome. Aside from a dizzying array of discomforts associated with the malady, the lack of a definitive cause, and few remedies offered by the medical establishment, scornful skeptics lob accusations of laziness or boredom or just plain moodiness. "Snap out of it!" they say, with little sympathy or understanding. "Just get moving!" But if you're one of more than 3 million Americans affected by chronic fatigue, you know your problem is not all in your head. Your symptoms are real and they extend far beyond mere tiredness. In addition to a debilitating sense of fatigue that can make everyday existence feel like an overwhelming struggle, you may suffer from impaired concentration and memory, recurrent sore throats, nagging headaches, muscle and joint pain, swollen lymph nodes and fitful sleep. The persistence of any one of these effects alone could be debilitating, but the overall diminished capabilities of the chronic fatigue sufferer can become the most discouraging aspect of the disease. But before you give up hope on kicking this energy-sucking ailment, look to natural ways to boost your immune system and regain your stamina for a more healthy and productive life. New research points to powerful, energy enhancing supplements which, combined with a nutritious diet and stress reducing techniques, can help you reclaim your body from a swamp of sluggishness. Yuppie Flu? Part of the public's misconceptions about chronic fatigue syndrome (CFS) may stem from vague definitions of exactly what it is and its causes. In the '80s, CFS was often mentioned in the same breath as the Epstein-Barr virus, which garnered much notoriety as the "yuppie flu": a state of chronic exhaustion that often plagued young, overworked professionals, as the media trumpeted. CFS was initially thought to be the result of the Epstein-Barr virus, and the two were often considered to be the same thing. Since the Epstein-Barr virus causes mononucleosis, the term "chronic mono" was also thrown around to refer to long-lasting states of fatigue. Today, CFS is defined as a separate disorder from the Epstein-Barr syndrome. Researchers have found that CFS is not caused exclusively by the Epstein-Barr virus or any other single infectious disease agent. According to the Centers for Disease Control (CDC) in Atlanta, CFS may have multiple causes, in which viruses or other infectious agents might have a contributory role. Some of these additional possible culprits include herpes simplex viruses, candida albicans (yeast organisms), or parasites. According to the CDC, a person can be definitively diagnosed with CFS when she or he experiences severe chronic fatigue for six months or longer that is not caused by other medical conditions, and must have four or more of the following problems recurrently for six consecutive months: tender lymph nodes, muscle pain, multi-joint pain without swelling or redness, substantial impairment in short-term memory or concentration; sore throat, headaches, unrefreshing sleep and postexertional malaise lasting more than 24 hours. Even if you are not diagnosed with CFS, you could still probably use some help in fending off fatigue. You may suffer from another poorly understood condition like fibromyalgia, which causes similar symptoms of exhaustion and pain with additional stomach discomfort. You may cope with another ailment like hypoglycemia or low thyroid function that zaps your energy. Or you could be like almost every stressed-out American adult trying to do it all at the expense of your well-being. Though researchers still search for a definitive cause for CFS, one thing is certain: Constant stress and poor nutritional habits weaken the immune system's ability to ward off a host of debilitating viruses and organisms. So before you run yourself down and succumb to a chronic condition, learn how you can build up your defenses now. Nutrient News Some of the most exciting new research in CFS treatments focuses on NADH or Coenzyme 1, an energy-enhancing nutritional supplement. This naturally-occurring substance is present in all living cells including food, although cooking destroys most of it. Coenzymes help enzymes convert food and water into energy and NADH helps provide cellular fuel for energy production. It also plays a key role in cell regulation and DNA repair, acts as a potent antioxidant, and can reportedly improve mental focus and concentration by stimulating cellular production of the neurotransmitters dopamine, noradrenaline and serotonin. A recent study conducted at Georgetown University Medical Center in Washington, DC, and reported in the February 1999 issue of The Annals of Allergy, Asthma & Immunology, showed that chronic fatigue sufferers improved their condition significantly by taking Enada, the stabilized, absorbable, oral form of NADH. The researchers found that 31% of those who took the supplement achieved significant improvement in relief of their symptoms, and a follow up study showed that 72% achieved positive results over a longer period of time. Coenzyme-A and Coenzyme Q-10 (Co-Q10) are related coenzymes also necessary for energy production. According to Erika Schwartz, M.D., and Carol Colman, authors of Natural Energy: From Tired to Terrific in 10 Days (G.P. Putnam's Sons) CoQ10 in combination with the nutrient carnitine enhances cellular energy production, thereby boosting energy levels. Coenzyme-A is required to initiate the chemical reactions that involve the utilization of CoQ10 and NADH for the production of energy at the cellular level. Another important energy-enhancing nutrient is D-ribose, a simple sugar that is crucial to many processes in your body. D-ribose stimulates the body's production of adenosine triphosphate, or ATP, an energy-rich chemical compound that provides the fuel for all body functions. D-ribose is essential to the manufacture of ATP and maintaining high levels of energy in the heart and skeletal muscles. Vitamin Power In addition to these new nutrients, a host of more familiar vitamins and minerals can help banish fatigue. According to Susan M. Lark, M.D., author of the Chronic Fatigue Self Help Book (Celestial Arts) nutritional supplements help stimulate your immune system, glands and digestive tract, promote proper circulation of blood and oxygen, and provide a calming effect. Some of Lark's recommended nutrients for building and regaining strength include: Vitamin A: Helps protect the body against invasion by viruses that could trigger CFS, as well as bacteria, fungi and allergies. Supports the production and maintenance of healthy skin and mucous membranes, the body's first line of defense against invaders. Also supports the immune system by boosting T-cell activity and contributing to the health of the thymus, the immune-regulating gland. Vitamin B Complex: Depression and fatigue can result from the body's depletion of B vitamins, which can occur from stress or drinking too many caffeinated beverages. Studies have provided preliminary evidence that CFS patients have reduced functional B vitamin status (J R Soc Med 92 [4], Apr. 1999: 183-5). The 11 factors of B complex are crucial to glucose metabolism, stabilization of brain chemistry and inactivation of estrogen, which regulate the body's levels of energy and vitality. n Vitamin C: Helps prevent fatigue linked to infections by stimulating the production of interferon, a chemical that can limit the spread of viruses. Helps fight bacterial and fungal infections by maintaining healthy antibody production and white blood cells. Also necessary for production of adrenal gland hormones which help prevent exhaustion in those under stress. Bioflavonoids: Help guard against fatigue caused by allergic reactions; their anti-inflammatory properties prevent the production of histamine and leukotrienes that promote inflammation. Bioflavonoids like quercetin are powerfully antiviral. Vitamin E: Has a significant immune stimulation effect and, at high levels, can enhance immune antibody response. Zinc: Immune stimulant; improves muscle strength and endurance. Constituent of many enzymes involved in metabolism and digestion. n Magnesium and Malic Acid: Important for the production of ATP, the body's energy source. Magnesium is also important for women who may develop a deficiency from chronic yeast infections. Potassium: Enhances energy and vitality; deficiency leads to fatigue and muscle weakness. Calcium: Combats stress, nervous tension and anxiety. Iodine: Necessary to prevent fatigue caused by low thyroid function, as it is crucial for the production of the thyroid hormone thyroxin. Herbal Helpers In addition to nutrients to bolster your immunity, herbal remedies can also help suppress viral and candida infections. Garlic is a powerful, natural antibiotic, while echinacea and goldenseal have strong anti-infective abilities. Other botanicals help combat tiredness and depression: stimulating herbs such as ginger, ginkgo biloba, licorice root and Siberian ginseng can improve vitality and energy. For anxiety, moodiness and insomnia try passionflower or valerian root, which both have a calming effect on the central nervous system. Eating For Energy Supplements can only do their best if you eat a nutritious diet. Start by cutting out large quantities of sugar, caffeine, alcohol, dairy products, red meat and fat. But what are the best foods when trying to restore energy or recover from illness? "High nutrient content foods with a good balance of proteins and carbohydrates," answers Jennifer Brett, ND, interim clinic director and chair of botanical medicine at the University of Bridgeport College of Naturopathic Medicine. "You want foods with high nutritional value-that's where vegetables end up looking better than fruit." Brett enthusiastically pushes that "universal food," as she calls it: chicken soup. "In China," she says, laughing, "they do make chicken soup, and they do think of it as healing, because they add astragalus and shiitake mushrooms. Vegetable soups with chicken or fish have high nutritional value and are easy to digest." The same principle applies to juices, Brett says. Juices are a good way to tastefully get more phytonutrients from fruits and vegetables into your diet. Toss in protein powder, and you can make a complete meal in your blender. "You get more energy from juicing," she explains, "more accessible nutrients and carbohydrates that are not bound up in fiber." Brett's additional recommendation: oatmeal. "It's got protein and carbohydrates combined with a lot of minerals, which you may not get from a sugary cereal," she says. "Sure, they spray some vitamins on them, but if you don't drink the milk in the bottom of the bowl, you'll miss out on them. You might as well take a multivitamin." Fabulous Fiber Look to fiber for superior energy enhancement. Natural Energy author Schwartz calls it downright "miraculous": "In terms of conserving precious energy, fiber-rich foods are your cells' best friends," she writes. "It takes smaller quantities of them to give you a full, satisfied feeling. They release all their benefits slowly, which allows the cells to extract nutrients with much less effort. Then these fiber-rich foods graciously leave the body with ease and efficiency." Among these "slow burn" foods that Schwartz says raise blood sugar slowly and steadily and maintain energy evenly: Alfalfa sprouts-high in fiber and low in cholesterol. Apples-one medium unpeeled provides 10% of the recommended daily fiber dose; unlike sweeter fruits, which are rich in healthful fiber, they help regulate blood sugar. Broccoli-along with such greens as cauliflower, cabbage, kale, collard greens and broccoli rabe, it's packed with fiber, vitamins and minerals n Brown rice, wild rice, other whole grains-fiber treasure troves, including barley, quinoa, millet and buckwheat. Corn-excellent fiber source. Lentils and other legumes-high in fiber, delicious beans are rich in culinary possibilities. Oat bran and wheat bran-mix into yogurt or add to cereal for the best available access to fiber. Popcorn-an excellent snack. Citrus for More Energy If constant colds and infections are draining your energy, healthy helpings of citrus fruit may be the pickup you need. According to Robert Heinerman, in Heinerman's Encyclopedia of Healing Juices (Parker), citrus fruit have been used for more than a thousand years as natural remedies for a wide variety of ailments: Kumquat juice is supposed to help clear up bronchitis. Lemon juice with a pinch of table salt eases a sore throat. Lime juice in warm water soothes aches and cramps from the flu. Tangerine juice can break up mucous congestion in the lungs. Along with citrus' vitamin C, these fruits also supply carotenoids, antioxidants that provide disease-preventing benefits. Citrus also often contain calcium, potassium, folate (a B vitamin that fights against heart disease), iron and fiber. Fruits are loaded with phytochemicals, naturally occurring chemicals that give fruit their vibrant colors. Yellow, red and orange fruits are also high in flavonoids, like quercetin, a substance which fights cancer. Quercetin also aids in prevention of cataracts and macular degeneration, according to author Stephanie Beling, MD, in her book Power Foods (Harper Collins). Even the US Department of Agriculture agrees on this flavonoid's benefits, noting in its phytochemical database that quercetin is an "antitumor promoter, antiasthmatic, anticarcinogenic, antiplaque, cancer-preventive, capillariprotective." (Quercetin is also available as a supplement.) Don't Avoid Avocados For a vitamin rich food, few items beat the avocado which holds vitamins E and C as well as some B vitamins (B6, niacin, riboflavin). A significant source of beta carotene, though not nearly as much as carrots or sweet potatoes, avocados also contain high amounts of the minerals potassium, magnesium, copper and zinc. Just 15 grams of avocado delivers about 81 international units of vitamin A as beta carotene. Beta carotene, a carotenoid in fruits and vegetables, is converted to vitamin A in the body. This vitamin, aside from providing antioxidant protection from damaging free radicals, is necessary for good eyesight, healthy skin and healing. In addition, the avocado, like all of these healthy foods, tastes great. Which means that you can pep up and not have to sacrifice taste for zest. Healthy Mind, Healthy Body Remember that the path to wellness begins in your mind. Stress-reducing activities like yoga, meditation and massage and aromatherapy can have a great rejuvenating effect on your body. If you can learn to handle stress effectively instead of letting it control you-and strengthen your system with the right nutrients and diet-you'll find that fatigue can be a sporadic visitor rather than a chronic companion.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=284) You Are What You Digest
Date:
June 10, 2005 04:50 PM
You Are What You Digest by Anthony J. Cichoke, DC Energy Times, September 2, 1999 Does your dinner creep back to haunt you in the ghostly morning hours? Does a mere glance in the direction of the local Mexican cafe or barbecue palace fill you with dread (to say nothing of internal discomfort)? We tend to ignore our digestive systems-the ever-ready, always reliable iron-clad stomachs of our youth, into which we stuffed pizza, peppers and beer-until diarrhea, gas, heartburn, bloating, constipation, stomach pain or other, much more serious, problems develop. According to the National Institutes of Health, more than 62 million Americans experience some type of digestive distress. More than 10 million people suffer from hemorrhoids, nearly 3 million from gastritis and duodenitis, 2.3 million from inflammatory bowel disease, almost 4.5 million from constipation and 1.4 million from irritable colon. (Statistics from Digestive Diseases in the United States: Epidemiology and Impact, edited by James E. Everhart and published in 1994 in Washington, DC, by the US Department of Health and Human Services, Public Health Service, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases.) Many conditions such as hemorrhoids or constipation are relatively benign, while others, notably chronic liver disease, malignancies and ulcers, can be life-threatening. In my long career as a chiropractor with an intense interest in nutrition, I have studied and written about the powers of enzyme therapy to prevent and treat the common and related problems of indigestion, heartburn, gas, lactose intolerance and constipation. Poor Digestion: The Costs Impaired digestion takes a dangerously high toll in causing nutrient deficiencies. For example, the stomach needs sufficient hydrochloric acid to activate the digestive enzyme pepsin, a substance which helps break down the proteins you eat into the short chains of amino acids (protein building blocks) that go into strong muscles, fight disease and produce a healthy supply of blood. Poor digestion can also impair your absorption of carbohydrates and fats as well as many vitamins and minerals. Vitamin E, for example, is fat soluble, that is, stored for long periods in the body's fat cells, rather than rapidly excreted like the water soluble vitamin C. Vitamin Absorption Impaired pancreatic function, or insufficient lipase or bile production, will inhibit fat digestion, possibly causing insufficient absorption of vitamin E, according to the book Present Knowledge in Nutrition (International Life Sciences Institute, Nutrition Foundation, Washington, DC), which is edited by Myrtle L. Brown. Thus, any difficulty in digesting and absorbing dietary fat can appreciably decrease vitamin E digestion and absorption. In fact, insufficient fat intake coupled with troubled digestion and absorption can affect the body's use of all the fat soluble vitamins-A, D, E and K. The Enzyme-Digestion Team Enzymes are molecules naturally produced by the body. These dynamos are involved in all physiological functions but are probably best known for the many jobs they perform during the process of digestion. Digestive enzymes break the food you eat down into smaller particles so the body can better absorb vitamins, minerals and other nutrients. Unfortunately, in many cases, we may become deficient in digestive enzymes. Or, on the other hand, the enzymes we do produce may be inadequate for proper digestion. Luckily, supplemental enzymes can compensate for nature's shortfalls. Enzyme Boosters Supplemental enzymes, available in tablets, capsules, powders and pills, can help enhance the digestive process. The most popular enzymes for this use include: Proteases help the body digest proteins by breaking them down into their component amino acids. Lipases break down fat molecules into smaller pieces for better digestion. Amylases break down carbohydrates. Digestive enzymes also function in a wide variety of ways: They detoxify and cleanse the colon and stimulate the beneficial bacteria in the gut, thereby helping relieve a number of digestion-related disorders. They help mobilize and remove toxic products from the body. Supplemental enzymes can be used in basically three ways: as digestive aids, taken with or just prior to meals to help break down foods, freeing their nutrients for absorption and use by the body; as systemic enzyme therapy taken between meals and intended to be absorbed into the bloodstream and carried throughout the body to work intensively and thoroughly at the cellular level. They are consumed between meals to avoid mixing them with food as it is consumed. Energizing Enzymes Enzymes used systemically can energize the digestive, immune, cardiovascular and nervous systems. In addition, they can also help fight viruses, bacteria, toxins and inflammation, a common symptom with many digestive disorders including diverticulitis and gastritis. The third way to take supplemental enzymes is in a form I call Enzyme Absorption System Enhancers (EASE), commercially produced enzymes combined with herbs, vitamins, minerals and other nutrients designed to improve their activity, absorption and bioavailability (readiness and ease with which the body can take them up). Enzymes for Common Conditions From my extensive research and experience, enzymes as digestive aids, in systemic enzyme therapy as as EASE, can treat more than 150 common health conditions. Choose your enzyme supplements carefully, scrutinizing the label thoroughly for: directions for use formulation (coated or uncoated) the enzymes in the formulation and their sources; a vegetarian would want to avoid enzymes from animal sources and those with allergies should ensure that the formulation is free of potential allergens. However pervasive digestive problems are, there's no reason why they have to get you down, ruin your digestion or inflate you. These are very useful substances: Enzymes can set your digestive system - and most of your body's functions - back on track. Remember, enzymes are essential keys to the smooth, efficient function of that wonderful machine, the human body. Because enzyme production and activity decrease with age, trauma and illness, make a firm commitment to daily enzyme supplementation for a healthier, happier, longer life.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=277) Glycerylphosphorylcholine -- Supports Cognitive Function in AD ...
Date:
May 24, 2005 09:52 AM
Cognitive Improvement in Mild to Moderate Alzheimer's Dementia After Treatment with the Acetylcholine Precursor Choline Alfoscerate: A Multicenter, Double-Blind, Randomized, Placebo-Controlled Trial Maria De Jesus Moreno Moreno, MD Instituto Nacional de la Senectud, Mexico City, Mexico
in both men and woman they consistently improved after 90 and 180 days versus baseline with adiministration of GPC three times a day, whereas in the placebo group they remained unchanged or worsened. Statistically significant differences were observed between treatments after 90 and 180 days. Keypoints: references: Bartus RT, Dean RL III, Beer B, Lippa AS. The cholinergic hypothesis of geriatric memory dysfunction, Science. 1982;217:408-414. 2. Larson EB, Kukull WA, Katzman RL. Cognitive impairment: Dementia and Alzheimer's disease. Annu Rev Public Health. 1992;13:431-449. 3. Hofman A, Rocca WA, Brayne C, et al, for the European Prevalence Research Group. The prevalence of dementia in Europe: A collaborative study of 1980-1990 findings. Int d Epidemiol. 1991;20:736-748. 4. Blackwood W, Corsellis JAN, eds. Greenfield's Neuropathology. 3rd ed. London: Arnold; 1976. 5. Geldmacher DS. Cost-effective recognition and diagnosis of dementia. 5emin Neurol. 2002;22:63-70. 6. Perry EK, Tomlinson BE, Blessed G, et al. Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia. BMJ. 1978;2:1457-1459. 7. Perry EK. The cholinergic hypothesis--ten years on. Br Med Bull. 1986;42:63-69. 8. Giacobini E. From molecular structure to Alzheimer therapy. Jpn d Pharmacol. 1997;74:225-241. 9. Giacobini E. Invited review: Cholinesterase inhibitors for Alzheimer's disease therapy: From tacrine to future applications. Neurochem Int. 1998;32:413-419. 10. Brinkman SD, Smith RC, Meyer JS, et al. Lecithin and memory training in suspected Alzheimer's disease. J Gerontol. 1982;37:4-9. 11. Davis E, Emmerling MR, Jaen JC, et al. Therapeutic intervention in dementia. Crit Rev Neurobiol. 1993;7:41-83. 12. Amenta E Parnetti L, Gallai V, Wallin A. Treatment of cognitive dysfunction associated with Alzheimer's disease with cholinergic precursors. Ineffective treatments or inappropiate approaches? Mech Ageing Dev. 2001;122:2025-2040. 13. Sigala S, Imperato A, Rizzonelli P, et al. k-Alpha-glycerylphosphorylcholine antagonizes scopolamine-induced amnesia and enhances hippocampal cholinergic transmission in the rat. Eurd Pharmacol. 1992;211:351-358. 14. Govoni S, Battaini E Lucchi L, et al. Effects of alpha-glycerylphosphorylcholine in counteracting drug-induced amnesia: Through cholinergic and non-cholinergic mechanisms [in Italian]. Basi Raz Ter. 1991;21:75-78. 15. Canonico PL, Nicoletti F, Scapagnini U. Neurochemical and behavioral effects of alpha-glycerylphosphorylcholine [in Italian]. Basi Raz Te~ 1990;20: 53-54. 191 CLINICAL THERAPEUTICS ® 16. Parnetti L, Amenta E Gallai V. Choline alphoscerate in cognitive decline and in acute cerebrovascular disease: An analysis of published clinical data. Mech Ageing Dev. 2001;122:2041-2055. 17. Venn RD. The Sandoz Clinical Assessment-Geriatric (SCAG) scale. A general-purpose psychogeriatric rating scale. Gerontology. 1983;29:185-198. 18. Di Perri R, Coppola G, Ambrosio LA, et al. A multicentre trial to evaluate the efficacy and tolerability of alpha-glycerylphosphorylcholine versus cytosine diphosphocholine in patients with vascular dementia. J Int Med Res. 1991;19:330-341. 19. Frattola L, Piolti R, Bassi S, et al. Multicenter clinical comparison of the effects of choline alphoscerate and cytidine diphosphocholine in the treatment of multi-infarct dementia. Curt Ther Res Clin Exp. 1991;49:683-693. 20. Muratorio A, Bonuccelli U, Nuti A, et al. A neurotropic approach to the treatment of multi-infarct dementia using L-c~-glycerylphosphorylcholine. Curt Ther Res Clin Exp. 1992;52:741-75l. 21. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. Washington, DC: APA; 1994. 22. McKhann G, Drachman D, Folstein M, et al. Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology. 1984;34:939-944. 23. Folstein ME Folstein SE. "Mini-mental state": A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975; 12:189-198. 24. Loeb C, Gandolfo C. Diagnostic evaluation of degenerative and vascular dementia. Stroke. 1983;14:399-401. 25. Hamilton M. A rating scale for depression.J Neurol Neurosurg Psychiatry. 1960;23:56-62. 26. Hamilton M. Development of a rating scale for primary depressive illness. BrJ Soc Clin Psych& 1967;6:278-296. 27. Rosen WG, Mohs RC, Davis KL. A new rating scale for Alzheimer's disease. AmJ Psychiatry. 1984;141:1356-1364. 28. Reisberg B, Ferris SH, De Leon MJ, et al. The Global Deterioration Scale for assessment of primary degenerative dementia. Am J Psychiatry. 1982;139:1136-1139. 29. National Institute of Mental Health. Clinical global impressions. In: Guy W, ed. ECDEU Assessment for Psychopharmacology. Revised edition. Rockville, Md: National Institute of Mental Health; 1976:217-222. 30. Burns A, Russell E, Page S. New drugs for Alzheimer's disease. Br J Psychiatry. 1999;174:476-479. 31. Kumar V, Anand R, Messina J, et al. An efficacy and safety analysis of Exelon in Alzheimer's disease patients with concurrent vascular risk factors. Eur J Neurol. 2000;7:159-169. 32. Knapp MJ, Knopman DS, Solomon PR, et al, for the Tacrine Study Group. A 30-week randomized controlled trial of high-dose tacrine in patients with Alzheimer's disease. JAMA. 1994;271:985-991. 192 M. Moreno 33. Lindstrom MJ, Bates DM. Newton-Rapshon algorithms for linear-mixed effects models for repeated measure data. J Am Stat Assoc. 1998;83:1014-1022. 34. Thai LJ, Carta A, Clarke WR, et al. A 1-year multicenter placebo-controlled study of acetyl-L-carnitine in patients with Alzheimer's disease. Neurology 1996;47:705-711. 35. Rogers SL, Friedhoff LT, for the Donepezil Study Group. The efficacy and safety of donepezil in patients with Alzheimer's disease: Results of a US multicentre, randomized, double-blind, placebo-controlled trial. Dementia. 1996;7:293-303. 36. Rogers SL, Doody RS, Mohs RC, Friedhoff LT, for the Donepezil Study Group. Donepezil improves cognition and global function in Alzheimer disease: A 15-week, double-blind, placebo-controlled study. Arch Intern Med. 1998; 158:1021-1031. 37. Corey-Bloom J, Anand R, Veach J, for the ENA 713 B352 Study Group. A randomized trial evaluating the efficacy and the safety of ENA 713 (rivastigmine tartrate), a new acetylcholinesterase inhibitor, in patients with mild to moderately severe Alzheimer's disease. Int J Geriatr Psychopharmacol. 1998;1:55-65. 38. Rosler M, Anand R, Cicin-Sain A, et al. Efficacy and safety of rivastigmine in patients with Alzheimer's disease: International randomised controlled trial. BMJ. 1999;318: 633-638. 39. Amenta E Bronzetti E, Del Valle M, Vega JA. Effects of alpha-glycerylphosphorylcholine in neuroanatomy of aging brain in experimental animals [in Italian]. Basi Raz Te~: 1990;20:31-38. Address correspondence to: Scientific Department, Italfarmaco SpA, via dei Lavoratori 54, 20092 Cinisello Balsamo, Milan, Italy.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=98) Effects of a novel formulation of essential oils on glucose–insulinmetabolism in diabetic 
Date:
May 18, 2005 09:20 AM
Background: Insulin resistance and its most severe form type 2 diabetes mellitus are rapidly increasing throughout the world. It is generally recognized that natural products with a long history of safety can increase insulin sensitivity. Aims: The present investigation examined the ability of various combinations of essential oils such as fenugreek, cinnamon, cumin, oregano, etc. to enhance insulin sensitivity. As a first approximation, we examined the effects of these natural products on Zucker fatty rats (ZFRs), a model of obesity and insulin resistance, and spontaneously hypertensive rats (SHRs), a model of genetic hypertension. Material and Methods: Water or essential oils were given orally via droplets, and insulin sensitivity was estimated by systolic blood pressure (SBP) changes and circulating glucose and/or insulin concentrations. Results: We have found that the ability to alter SBP in rat models is the most sensitive early index of insulin sensitivity. The combined essential oils lowered circulating glucose levels and SBP in both ZFRs and SHRs, suggesting that these natural products are enhancing insulin sensitivity. The second series of studies examined two additional combinations of essential oils along with the original formula. The major differences were in the types and proportions of individual oils contributing to a given formula. Conclusions: Although all the three formulae decreased SBP in ZFRs, one of the formulae was more effective than the others in lowering circulating glucose in the glucose tolerance testing. Accordingly, some essential oils may be added to the long list of natural products that can affect insulin sensitivity. Keywords: diabetes mellitus, essential oils, insulin resistance, insulin sensitivity, insulin sensitivity, natural products Received 11 August 2003; returned for revision 25 September 2003; revised version accepted 16 March 2004 Introduction The prevalence of insulin resistance and its most severe form type 2 diabetes mellitus is rapidly increasing in the USA – even throughout the world [1–3]. The recent increase is attributed, at least to some extent, to the greater occurrence of overweight and obesity that is due mainly to an augmented intake of calories and refined carbohydrates, lesser consumption of fibres and a more sedentary lifestyle [4–6]. Obviously, reversal of these situations should ameliorate the problem. Unfortunately, more is often needed than simply advising lifestyle changes that frequently fail in order to combat insulin resistance and its accompanying perturbations (cardiovascular diseases, obesity, dyslipidemias, diabetes mellitus and premature ageing) [7,8]. Experience shows that the afflicted not infrequently require aids to help with the maintenance of a healthful lifestyle. Correspondence: Harry G. Preuss, D, Georgetown University Medical Center, Department of Physiology and Biophysics, Basic Science Building, Room 231B, 4000 Reservoir Road, N.W., Washington, DC 20057, USA. O R I G I N A L ART I C L E doi: 10.1111/j.1463–1326.2004.00386.x # 2004 Blackwell Publishing Ltd Diabetes, Obesity and Metabolism, 7, 2005, 193–199 193
Cinnamon Extract and Blood sugar 60ctCinnamon Extract and Blood Sugar 120ct
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