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How to Treat Myocarditis Naturally: Anti-inflammatory Supplements and Herbs for a Strong Heart
June 23, 2022 01:46 PM
Myocarditis is a condition that affects the heart muscle. It can be caused by a variety of things, including infection, autoimmune diseases, and even certain medications. Left untreated, myocarditis can lead to heart failure or even death. Thankfully, there are many natural ways to treat this condition. We will discuss the anti-inflammatory supplements and herbs that can help strengthen your heart and improve your health!
What is myocarditis and what are the symptoms?
Myocarditis is an inflammation of the heart muscle. The condition can be caused by a viral infection, autoimmune disease, or exposure to certain drugs or toxins. Symptoms of myocarditis include chest pain, shortness of breath, and irregular and/or rapid heartbeat. In severe cases, myocarditis can lead to heart failure. Treatment for myocarditis typically involves rest and limiting physical activity. In some cases, medication may also be necessary to reduce inflammation and prevent complications.
How can anti-inflammatory supplements and herbs help treat myocarditis naturally?
Herbs and supplements that have anti-inflammatory properties can be helpful in treating myocarditis, according to recent studies. Myocarditis is an inflammation of the heart muscle, and can be caused by a viral infection, autoimmune disease, or exposure to toxins. The condition can lead to arrhythmias, congestive heart failure, and even death. While there is no cure for myocarditis, treatment focuses on reducing inflammation and preventing further damage to the heart. Several herbs and supplements have been shown to have anti-inflammatory properties, including turmeric, ginger, and omega-3 fatty acids. In addition, these natural remedies are generally well-tolerated and have few side effects. As a result, they may offer a safe and effective way to manage myocarditis.
What are some of the best supplements and herbs for treating myocarditis naturally?
Treatment for myocarditis typically focuses on relieving symptoms and supporting the heart. However, there are also a number of supplements and herbs that can be beneficial for treating myocarditis naturally. Turmeric is a potent anti-inflammatory agent that has been shown to be effective in treating myocarditis. CBD is another compound with anti-inflammatory properties that can help to reduce inflammation in the heart. Omega-3 fatty acids are also beneficial for reducing inflammation and supporting heart health. Hawthorne berry is a herb traditionally used for the treatment of heart conditions. It helps to improve circulation and reduce strain on the heart. D-ribose is a sugar molecule that is essential for energy production in the cell. It helps to support the metabolism and can be beneficial for those with myocarditis. CoQ10 is an antioxidant that helps to protect the heart from damage caused by free radicals. CoQ10 is also involved in the krebs cycle the energy cycle of each cell. Supplements can be helpful for treating myocarditis naturally.
How can I incorporate these supplements and herbs into my treatment plan for myocarditis?
Treatment typically involves a combination of medications, rest, and lifestyle changes. Some people also find that supplements and herbs can help to relieve symptoms and promote healing. Turmeric, CBD, omega-3 fatty acids, hawthorne berry, D-ribose, and CoQ10 are all thought to be beneficial for people with myocarditis. Speak with your doctor before taking any supplements, as some can interact with medications you may be taking for your condition. However, when used correctly, these supplements and herbs can be helpful in managing myocarditis.
Are there any risks associated with using these supplements and herbs to treat myocarditis naturally?
There are a few potential risks associated with using natural supplements to treat myocarditis. Some of these supplements, such as turmeric and omega-3 fatty acids, may thin the blood. As a result, people who are taking blood thinners should have their blood levels monitored regularly. Additionally, Hawthorne berry may lower blood pressure, so people with low blood pressure should use it with caution if on medication. Finally, while CoQ10 is generally considered safe, it can cause upset stomach in some people, always take supplements with food.
How can I ensure that I am getting the most benefit from these supplements and herbs in order to improve my heart health?
Always start out with the recommended dosage for a week, then slowly increase each as needed. Make sure you spread out the consumption of supplements over the entire day to help reduce inflammation all day and night long. For example, supplements can be taken at breakfast, lunch, dinner and bedtime. Taking supplements spread out through the day ensure you get the therapeutic benefits all day long.
Using natural supplements and herbs to treat myocarditis can be a beneficial way to manage the condition. These supplements can help to reduce inflammation, improve circulation, and protect the heart from damage. When used correctly, they can be an effective part of a treatment plan for myocarditis. However, it is important to speak with your doctor before starting any new supplement regimen. It is also important to start out slowly when taking these supplements and increase dosage gradually to ensure you get the most benefit. Taking supplements throughout the day can help ensure that you receive their therapeutic benefits all day long.
The Kidneys and Your Health: Everything You Need to Know
April 29, 2022 03:10 PM
The kidneys are two bean-shaped organs that sit in the lower back, on either side of the spine. They play a vital role in your health, filtering toxins from the blood and regulating fluid balance in the body. We will discuss everything you need to know about the kidneys, including common kidney problems and how to keep them healthy!
What are the common kidney problems
The kidneys are a pair of organs that filter waste products from the blood and excrete them in urine. They are also responsible for regulating fluid and electrolyte balance in the body. Kidney problems can range from mild to severe, and can be acute or chronic. Common kidney problems include kidney stones, urinary tract infections, and Nephrotic Syndrome. Kidney stones are small, hard deposits that form in the kidney when there is an imbalance of minerals in the urine. Urinary tract infections occur when bacteria enter the urinary system and multiply. Nephrotic Syndrome is a kidney disorder that causes the body to excrete large amounts of protein in the urine.Kidney problems can often be treated with medication, but in some cases, surgery may be necessary. Early diagnosis and treatment is important to prevent serious complications.
Acute renal failure
Acute renal failure is a sudden onset of kidney failure that can be life-threatening. The kidneys are responsible for filtering waste from the blood and balancing fluids in the body. When they are not working properly, waste can build up in the blood and cause serious health problems. Acute renal failure can be caused by a number of factors, including dehydration, infection, and certain medications. Symptoms include decreased urine output, swelling, fatigue, and confusion. If left untreated, acute renal failure can lead to coma and death. Early diagnosis and treatment is essential for a successful outcome.
Chronic renal failure
Chronic renal failure, or CRF, is a serious medical condition that affects the kidneys. In this condition, the kidneys become damaged and unable to function properly. As a result, toxins can build up in the body, causing a variety of symptoms. Some of these symptoms may include fatigue, bloating and swelling, nausea, diarrhea or constipation, poor appetite, changes in urination frequency or color, and anemia. Diagnosing CRF involves examining several factors like blood test results and overall medical history. Treatment for the condition typically involves managing any associated symptoms with medication or dietary changes. In some cases, dialysis may also be necessary to support patients with severe CRF. Overall, chronic renal failure is a serious but manageable condition that requires careful monitoring and management by patients and their healthcare providers.
Renal artery stenosis
Renal artery stenosis refers to a condition in which one or more of the arteries that deliver blood to the kidneys becomes narrowed or blocked. This can lead to a number of adverse health effects, including increased blood pressure, chronic kidney failure, and possibly even heart attack or stroke. While there are a number of possible causes for this condition, including genetic factors, certain lifestyle choices such as smoking can also increase the risk of developing renal artery stenosis. Fortunately, treatments are available for this condition, including medications and medical procedures like angioplasty. For those who are diagnosed with renal artery stenosis, early and effective treatment is essential for maintaining overall health and wellbeing.
Renal cancer begins in the kidneys, which are a pair of bean-shaped organs that filter waste from the blood and produce urine. The most common type of renal cancer is clear cell renal cell carcinoma (RCC), which accounts for about three-quarters of all cases. RCC typically affects middle-aged adults and is more common in men than women. Other types of renal cancer include papillary renal cell carcinoma, chromophobe renal cell carcinoma, and collecting duct carcinoma. Treatment for renal cancer may include surgery, radiation therapy, chemotherapy, targeted therapy, or immunotherapy. The type of treatment will depend on the stage of the cancer and the patient's overall health. Early diagnosis and treatment is essential for the best possible outcome.
Polycystic kidney disease
Polycystic kidney disease, or PKD, is a complex condition that affects the kidneys and other organs in the body. This disorder occurs when small cysts grow in the kidneys, gradually interfering with their ability to filter waste products from the blood. As these cysts start to expand, they can cause a number of severe symptoms such as high blood pressure, chronic pain, nausea and fatigue. In some cases, PKD also results in serious complications such as renal failure or a stroke. However, there are treatments available that can help people manage this disorder and slow its progression over time. By working closely with a medical team and making lifestyle changes to support kidney health, it is possible for people living with PKD to have long and healthy lives.
Urinary tract infection
A urinary tract infection (UTI) is an infection that can occur in any part of the urinary system, including the kidneys, ureters, bladder, or urethra. UTIs are most commonly caused by bacteria, but they can also be caused by fungi or viruses. Symptoms of a UTI may include pain or burning during urination, increased frequency or urgency of urination, cloudy or blood-tinged urine, and pelvic pain. If left untreated, a UTI can lead to serious complications, such as kidney damage or sepsis. Early diagnosis and treatment is essential for preventing serious health problems. UTIs are typically diagnosed through urinalysis, which can detect the presence of bacteria or other organisms in the urine. Treatment usually involves antibiotics to kill the infection-causing bacteria. In some cases, hospitalization may be necessary to treat a severe UTI. Additionally, drinking plenty of fluids and emptying the bladder frequently can help to flush out bacteria and prevent reinfection. Wiping from front to back after using the restroom can also help to reduce the risk of UTI development. Avoiding masturbation devices would good idea if you get frequent urinary tract infections because they can introduce new bacteria into the urethra.
UTI and D-Mannose
A urinary tract infection, or UTI, is a common medical condition that can cause symptoms such as painful urination, abdominal discomfort, and sometimes even fever. While conventional treatments typically involve antibiotics, these medications often come with unwanted side effects like nausea and diarrhea. Fortunately, there is another alternative in the form of D-Mannose, a naturally-occurring sugar that has been shown to help treat UTIs by eliminating bacterial biofilms and relieving symptoms. Unlike antibiotics, which can damage gut health by killing off beneficial bacteria along with the harmful ones, D-Mannose does not disrupt this critical ecosystem. As a result, D-Mannose is becoming an increasingly popular treatment for UTIs, offering an effective and safe alternative to antibiotics.
Kidney stones are one of the most painful medical conditions to experience. These small, hard deposits form when there is an imbalance in the levels of certain minerals in the body. As they grow larger, kidney stones can cause severe pain as they move through the urinary tract. Treatment typically involves drinking plenty of fluids and taking pain medication. In some cases, surgery may be necessary to remove the kidney stone. Prevention is the best way to avoid kidney stones, and maintaining a healthy diet and lifestyle is the best way to do this. Drinking plenty of fluids, especially water, and eating a diet high in fiber can help to prevent kidney stones from forming.
Glomerulonephritis is a serious kidney condition that occurs when the tiny filtration units in the kidneys, known as glomeruli, become inflamed and damaged. This can disrupt normal kidney function, causing a buildup of waste products in the bloodstream, resulting in numerous symptoms such as swelling and joint pain. While there is no cure for glomerulonephritis, treatment options can help to reduce inflammation and manage symptoms. These may include medications to control blood pressure or reduce harmful inflammatory chemicals, along with lifestyle changes to support overall kidney health. With proper medical care and close monitoring, many people with glomerulonephritis are able to live healthy lives despite this chronic condition.
Kidney disease is a serious condition that can lead to a variety of health problems. If you have kidney disease, it is important to monitor your symptoms and seek medical treatment as soon as possible. There is no one-size-fits-all approach to managing kidney disease, but by working with your healthcare team and following their recommendations, you can help improve your health and quality of life. Remember, knowledge is power, so be sure to educate yourself about kidney disease and its treatment options. With the right information and support, you can live a full and productive life despite this serious condition.
No to Pain Pills and Yes to Safe and Effective Curcumin
September 04, 2020 11:05 AM
Many people turn to over the counter (OTC) drugs when they experience pain, the common ones are non-steroidal anti-inflammatory drugs, better known as NSAIDS. The problem with NSAIDS these drugs reduce an enzyme associated with pain called COX-1 and COX-2. There are a lot of hidden dangers behind prescription and OTC pain killers. Some of the most common ones consumed are Ibuprofen an d Acetaminophen.
Ibuprofen: a popular OTC pain reliever can cause stomach pain, nausea, gastric bleeding, ulcers, confusion, hypertension, increased heart attack and stroke. Also, swelling, rapid weight gain, reduced urination, which is a sign of kidney dysfunction, kidney failure, fever, sore throat, headache, rash, bruising, tingling, numbness, muscle weakness, neck stiffness, chills, light sensitivity, and seizures.
Acetaminophen: also known as Tylenol, is classified as an NSAID, but is also unsafe. The number one cause of liver failure in the United States is caused by acetaminophen next to alcohol consumption. If combined with alcohol, the damage to the liver is increased significantly. It also depletes glutathione, an important antioxidant needed by the liver to protect and detoxify the body. Over use of this OTC drug can cause nausea, vomiting, abdominal tenderness, and it can interfere with blood clotting, weaken kidney function, and with severe over dose can cause death.
The alternative: Curcumin is a safe and effective pain reliever
Curcumin is a compound from Turmeric Root, unstandardized turmeric powder contains only two to three percent curcumin. It is important to get a standardized curcumin so that you can get a therapeutic response from consuming this herb. Not all curcumin is the same, look for a brand that blends turmeric essential oil with curcumin to enhance the absorption of the product because the product is hard to absorb.
Curcumin is one of the worlds best studied herbs, it works by reducing a COX-2 response to inflammation the same target as many prescription and OTC drugs that cause organ damage and side effects. Fortunately, Curcumin can target the same in a safe and natural way with no side effects. It can prevent a wide spectrum of inflammatory and oxidative damage, relieve chronic pain as effective and much more safely than drugs like NSAIDs.
Taking OTC or prescription pain relieving drugs are not a long term solution for pain. With the side effects associated with common pain relievers, one should only take them as a last resort and consider using a safer alternative that is as effective to relieving pain. Terry Naturally offers BCM-95 a patented curcumin that is blended with turmeric essential oils, BCM-95 has been the subject of many clinical studies demonstrating its effectiveness in relieving pain. We at VitaNet offer free shipping on any product in Terry’s brand. If you are struggling with pain, consider trying Terry Naturally to help relieve pain safely.
Probiotics shown to protect against liver damage, study reveals
April 30, 2019 02:17 PM
Fatty Liver Disease is becoming a real issue and may impact up to 1/4th of the United States population. Thankfully there appear to be means of combating this disease. Probiotics have already contributed in reducing acetaminophen-caused liver disease particularly with lowering of the oxidative stress. Positive gut health and bacteria is also important in maintaining a healthy immune system and can contribute to further protecting the body against Fatty Liver Disease. Eating the right foods, including fermented varieties, helps promote good gut health.
"The team found that the supplemented mice experienced significantly less liver damage than the control group."
Read more: https://www.naturalhealth365.com/probiotics-nutrition-news-2623.html
Health Benefits Of Corn Silk | Health Tips Education
February 08, 2017 10:19 AM
There are many good uses for corn silk, it is a must have in any diet. Corn silk is used for bladder infections, inflammation of the urinary system, inflammation of the prostate, kidney stones, and bedwetting. It is also used to treat congestive heart failure, diabetes, high blood pressure, fatigue, and high cholesterol levels.https://www.youtube.com/watch?v=eCOObBMXsM4
"Corn silk is a common term to describe the shiny, thread-like, silky style on corn ears; the tuft or tassel of silky fibers growing at the tip of an ear of corn."
Heart disease protein could be connect to brain damage: Study
December 16, 2016 07:59 AM
Women over the age of 50 who follow a high-protein diet could be at higher risk for heart failure, especially if much of their protein comes from meat, according to preliminary research presented at the American Heart Association's Scientific Sessions 2016. Researchers evaluated the self-reported daily diets of 103,878 women between the ages of 50 and 79 years, from 1993 to 1998. A total of 1,711 women developed heart failure over the study period.
"The study, published online in the Journal of Radiology, has said that a substance or marker in the blood is indicative of sub-clinical heart disease and brain diseases like a stroke and or dementia, and could speed up initiation of treatments and lifestyle changes, potentially slowing or even reversing the disease’s course."
FDA Steps Up Warnings for Testosterone
November 02, 2016 03:49 PM
Testosterone and other steroid drugs can cause heart attacks, personality changes and infertility. The FDA also warned that people abusing high doses of testosterone have reported withdrawal symptoms such as depression, irritability, decreased libido, insomnia and others. Testosterone is not approved for treating the effects of aging. Anabolic steroids are synthetic variations of testosterone. These are prescribed to treat conditions such as delayed puberty and diseases that cause muscle loss like cancer or AIDS.
"They are legally prescribed to treat conditions such as delayed puberty and diseases that cause muscle loss, such as cancer or AIDS."
Health Benefits Of Taking L-Carnitine
November 04, 2013 07:18 PM
What is L –Carnitine
L –Carnitine is an amino acid that is naturally produced in the body. It is found in two different amino acids; methionine and lysine. Dietary sources of this amino acid include pork, beef and small amounts of milk, chicken and fish. This amino acid is highly required by the body and the following are the health benefits of Carnitine.
Important in the management of heart conditions
Carnitine is important in the management of a number of heart related conditions for example congestive heart failure, diphtheria, chronic chest pain, heart attack and high cholesterol. Studies show that Carnitine indeed is helpful in dealing with a number of heart related diseases.
Boosts overall brain function
A recent study shows that Carnitine aids in the recovery of stroke among animals. This clearly shows that this amino acid targets the brain cells. It contains nutrients that are highly required by the brain to function properly for example vitamins E, B-12 alpha-lipoic acid and folic acid.
Helps in burning body fat
Carnitine is a portent fat burner. It is needed in the transportation of fat into cells which will be used for the production of energy in the body. When the Carnitine levels are increased in the body, the body increases the fat burning process and then boosts energy levels in the body.
This amino acid can prevent diabetes and promotes cardio vascular health. With its antioxidant properties Carnitine eliminates free radicals and also reduces oxidative stress. This is very important in the improvement of your insulin health and also help in fat loss.
Improves male fertility
Studies show that adequate Carnitine levels in the body are necessary for male fertility. According to the study fertile males had adequate levels of this amino acid it was associated with healthier sperm. While the others who were considered infertile had compromised sperm health and lower Carnitine levels.
Green Tea - A Powerful Antioxidant
December 27, 2012 11:45 AM
Green tea which is basically obtained from the leaves of Camellia Sinensis, is treated as a medicinal herb. It is gaining popularity all over the world with its medicinal value, which is used to prevent many diseases.
Advantages of Green tea:
Consuming green tea on daily basis makes your bones stronger. This is because of the fluoride content present in it, which is very helpful in strengthening the bones.
Why is green tea a powerful antioxidant herb?
This herb is considered as powerful antioxidant herb because it EGCG content which helps the body kill free radicals which are harmful and which causes early aging of skin, liver transplantation failure, causes cancer, etc. Green tea contains very high concentration of antioxidants called polyphenols. It is beneficiary to take 2-3 cups of green tea or 2 - 3 - 500mg tablets every day. With regular exercise and proper diet, green tea helps in weight reduction.
Regular intake of green tea helps you to be healthy and prevents from attack of diseases. The anti oxidants, which are helpful in defending your body against diseases, are available in high concentration in green tea. It is advised to have at least a cup of green tea every morning on empty stomach.
Did You Know without Magnesium, You Could not Survive?
February 16, 2011 02:04 PM
Magnesium and your Health
Magnesium is vital to life on all levels. All types of cells in all organisms must maintain a balance of magnesium to support life as we know it, and its presence in human beings is ubiquitous at a cellular level. Low levels of magnesium have been tied to a number of medical conditions such as asthma, diabetes, and osteoporosis whereas excesses are known to impair functions of tissues and organs, notably nerves cells and the kidneys.
Supplies the Human Body with Energy
Glucose is best known as the primary source of energy of most multicellular organisms, including of course human beings, while adenosine triphosphate, or ATP, is the form of energy yielded by the utilization of glucose within the cells. All forms of carbohydrates and fats from our diet must be broken down into simpler compounds to be able to be converted into ATP that powers cellular activities.
That being said, ATP requires magnesium in its participation in a number of physiological functions. What we refer to as ATP in fact contains ions of magnesium, for the former must be chemically bound to the latter to perform its role in interactions with protein kinases. In fact, it is a common observation that magnesium almost always acts as the functional regulator in the binding of proteins with ATP.
Participates in Enzymatic Reactions
More or less 300 hundred enzymes in the body are dependent on ATP, which we refer to as coenzyme, a kind of chemical compound that binds to protein. Magnesium acts as glue that keeps the enzymes and ATP together, aiding in the catalytic activities brought about by the enzymes and their utilization of ATP. Thus, the metabolic pathways that employ these enzymes rely on the presence of magnesium.
One example of the interaction of ATP with proteins that necessitate magnesium as a divalent cation, in other words functional regulator, is in enzymes that modify the molecular structure of other proteins. These enzymes are transcribed in more than 500 protein genes and affect up to 30 per cent of all proteins in the human body. Moreover, magnesium plays a role in ribosome, the cellular component responsible for creation of RNA copies and the manufacture of proteins.
Magnesium Facilitates Absorption of Calcium
Over 60 per cent of magnesium in the body is stored in the bones, and this fact has become the basis of the recent trend of dietary supplements that utilize magnesium to induce healthy bone density. Indeed low levels of magnesium has been reported to contribute to the degeneration of bones as we age, resulting in porous bone particles in a medical condition called osteoporosis.
Prevents Ailments of the Circulatory System
Since magnesium is essentially everywhere in the body, it significantly impacts the overall health of the circulatory system, notably in the prevention of heart diseases. Not surprisingly, insufficient levels of magnesium have been documented to cause cardiovascular problems, including hypertension and congestive heart failure, and supplementation of magnesium has been noted to cut complications of preexisting circulatory conditions.
Have you had your magnesium today?
Natural Vitamins for the Heart
July 06, 2010 02:44 PM
It has been consistently revealed by epidemiological research that individuals with a high dietary intake of antioxidant vitamins have a risk that is lower-than-average of cardiovascular disease. This evidence seems to be especially consistent for vitamin E. Additionally, many clinical studies show that magnesium supplementation is of significant benefit in the treatment of cardiac arrhythmias and in reversing the depletion of potassium that comes along with a magnesium deficit. Many cardiovascular events like angina pectoris, congestive heart failure, and cardiomyopathy are related directly to low magnesium status. Coenzyme Q10 is an essential component in cellular energy production. This nutrient is also prevalent in the heart muscle. When tissue levels of CoQ10 are low, there is an association with several cardiovascular complications. Among these are angina, congestive heart failure, cardiomyopathy, hypertension, and mitral valve prolapse. Research has found that the trio of coenzyme Q10, vitamin E, and magnesium plays a crucial role in the maintenance of cardiac health and the prevention of disease states.
The cardio-protective effect of vitamin E seems to come from its ability to bind to LDL cholesterol, which protects it from free-radical induce oxidative damage along with the consequent buildup of atherogenic plaque. Low levels of vitamin E in the blood are a predictive factor of heart health almost 70% of the time.
Studies on the general population have suggested that there is a link between the intake of calcium and blood pressure. Although results of the studies have not been consistent, there are several studies showing that calcium supplementation can lower blood pressure in those individuals who experience hypertension. Overall, those intakes of calcium that are sub-optimal contribute directly to hypertension. It seems that dietary calcium reduces blood pressure by normalizing intracellular calcium levels.
Supplementation with magnesium is of benefit for the treatment of cardiac arrhythmias and the prevention of potassium depletion. Both magnesium and potassium play an important role in the functioning of the heart. Several studies have found that there is improvement in heart function in those patients that have cardiomyopathies when they supplement with magnesium. Since magnesium acts in so many ways to enhance cardiac function and optimize cellular metabolism, magnesium is widely recognized as a critical nutrient for general cardiac support.
Several double-blind studies have taken place in those patients that experience various cardiomyopathies in order to show the benefits of CoQ10 supplementation. One study reported an 89% improvement rate in 80 cardiomyopathy patients who were treated with CoQ10. The coenzyme also appears to moderate blood pressure through the usual mechanism, as it lowers cholesterol levels and also stabilizes the vascular system with its antioxidant properties. Because of this, it is able to reduce vascular resistance. Several studies on CoQ10 supplementation have confirmed that this nutrient posses the ability lower both systolic and diastolic pressures by up to ten percent.
There are other nutrients that play important roles in optimizing cardiovascular health and reducing hypertension. Among these nutrients are gamma tocopherol, calcium, magnesium, l-carnitine, acetyl-l-carnitine, procyanidolic oligomers, phenolic compounds, and lycopene. As you can see there are many natural supplements that can help the cardiovascular system. Remember to always consult your doctor before adding supplements to your diet while on prescription drugs. Look to your local or internet health food store for quality vitamins, herbs, and specialty formulas to boost your health and wellness.
Potassium And Magnesium
December 30, 2008 01:08 PM
Potassium and magnesium are the two most common minerals found within the cells of your body. They each have specific individual functions within your body, and together help to maintain the correct balance of electrolytes and the proper functioning of smooth and striated muscles. That includes allowing muscles to relax properly rather than to cramp.
Before discussing this, let's have a look at the major individual properties of these two metallic minerals with respect to the body's biochemistry.
Magnesium is needed to ensure the proper functioning of the sodium/potassium pump. This is a complex topic, and we shan't dwell on it at length here, although the basics are that it is responsible for the movement of ions into and out of cells. Sodium and potassium ions are moved in opposite directions across the cell plasma membrane, three sodium ions being pumped out for every two potassium ions pumped into the cell.
This is of particular importance to nervous cells responsible for transmitting impulses in response to specific stimuli. In the event of a magnesium deficiency, this pumping action is impaired and the sodium/potassium balance within and without the body cells are imbalanced. This in turn impairs the response of nerve cells to stimuli. Both magnesium and potassium can be depleted through the use of diuretics, in which case a magnesium supplement can redress the imbalance.
There are several consequences of such an electrolytic imbalance, some having potentially serious consequences. Many can cause death if left untreated, although the symptoms usually allow appropriate medical treatment prior to the condition becoming fatal, such treatment frequently involving administration of magnesium and potassium. Among these are:
Calcium overload in certain heart cells that reduces the effective use of oxygen and ATP and causes overactive contraction of the heart muscle.
Spasms in coronary blood vessels.
Over-activity of the striated muscle fibers, leading to cramps in the calf and thigh muscles, for example.
Cramp and pain in the smooth muscles of hollow organs such as the bladder or uterus that can also cause premature labor.
Several heart problems caused by an increase in energy consumption and a calcium overload and potassium deficiency that leads to cardiac ischemia and arrhythmia that continue to create a serious medical condition and hazard to life. Potassium, that can stop the heart if given in excess, can be just as harmful if present in too small a concentration.
The whole situation creates a self-perpetuating cycle that can be broken by a magnesium and potassium supplement that restores the correct gradient of potassium and magnesium across the cell membrane, improves the function of the sodium/potassium pump and reduces the excess cellular calcium by replacing it with magnesium.
This only works if both potassium and magnesium are taken together: just either alone is no good. It also takes time for the effect to occur, so the supplement is not suitable for emergency use. A regular supply can prevent the condition occurring.
There are many other properties that magnesium and potassium possess with regard to the body's biochemistry such as the effect of magnesium in activating certain enzymes. However, in discussing relaxation, both of these essential minerals have a significant part to play.
It has been mentioned that a magnesium and calcium deficiency causes spasms and cramps in the smooth and striated muscles, and the corollary is also true. Magnesium and potassium can be used to relieve such cramps, and relax muscle tissue. Hence, because it can relax excited smooth bronchial muscle tissue, magnesium can be used to relieve asthma attacks. The intravenous administration of magnesium is, in fact, an accepted and proven clinical treatment for acute asthma attacks.
In the same way, magnesium has been used to treat muscle spasms and cramps. Again, it is not an immediate treatment for emergency use, but can be used over a period of days to treat athletes with a history of muscle spasms. Such spasm frequently occur after prolonged periods of exercise, when magnesium and potassium, among other electrolytes, can be lost through a combination of sweating and urination.
However, this is not the only means by which magnesium is lost from your body cells, and probably not even the main one. Less obvious, but likely of more importance, is the transfer of magnesium from the plasma into the red blood cells (erythrocytes). The amount by which this occurs is directly proportional to the more anaerobic the exercise, hence the need by athletes and weightlifters for more magnesium. It can be rapidly lost through exercise with insufficient oxygen, and cause their muscles to cramp up.
Magnesium deficiency is common in Americans, although factors such as high calcium intake, alcohol intake, diuretics, and kidney and liver disease are more responsible for this than a dietary deficiency. Potassium is readily available in bananas, brown rice, potatoes, tomatoes and oranges and dietary deficiencies are not common although supplements are readily available.
Magnesium is also known to play an important part in the secretion and use of insulin by the body. Supplementation with magnesium can help diabetics to make best use of insulin, become more tolerant to glucose and improve the fluidity of the membrane of red blood cells. The mineral; also has a small but definite effect in lowering blood pressure. Other uses for magnesium supplements include congenital heart failure, where higher magnesium contents lead to greater life expectancy and chronic fatigue syndrome (CFS) where magnesium supplements can significantly increase energy levels.
Other uses to which your body puts potassium other than to allow proper muscle contraction and relaxation and to maintain the balance of electrolytes in the body, includes the function of brain and nerve neurons. This, however, is academic since should your potassium levels drop by 50%, death would result.
Potassium, Magnesium and Calcium are essential in maintaining the proper workings of your body cells, although the most visible effect of magnesium and potassium is their relaxation properties on the body, put to specific use by sportsmen and women, particularly those involved in the more anaerobic sports.
August 12, 2008 01:37 PM
Vitamin C is the most widely taken nutritional supplement on the market and is available in a variety of forms, including tablets, drink mixes, crystals in capsules or bulk powdered crystals. Vitamin C is present in mother's milk and, in lower amounts, in raw cow's milk, with pasteurized milk containing only trace amounts. This vitamin is most present in the liver and least present in the muscle but needed through out the body.
Vitamin C is required for the synthesis of collagen, an important structural component of blood vessels, tendons, ligaments, skin, and bone. Vitamin C can regenerate other antioxidants such as vitamin E; in the body vitamin E can regenerate C as well. This vitamin is required for the growth and repair of tissues in all parts of your body. Relatively large doses of vitamin C may cause indigestion, particularly when taken on an empty stomach.
It has been shown that smokers who have diets poor in vitamin C are at a higher risk of lung-borne diseases than those smokers who have higher concentrations of Vitamin C in the blood. Biological tissues that accumulate over 100 times the level in blood plasma of vitamin C are the adrenal glands, pituitary, thymus, corpus luteum, and retina.
Studies suggest the presence of large quantities of sugar either in the intestines or in the blood can slow absorption of this vitamin. Several studies have demonstrated a blood pressure lowering effect of vitamin C supplementation. Also, when consumed in high doses it appears to interfere with the blood thinning effects of warfarin by lowering prothrombin time, as noted in case reports in the 1970s so consult your doctor if on medications..
In one Study, researchers instructed patients with documented coronary artery disease to take a single oral dose of either 2 g vitamin C or a placebo. Results, the researchers discovered that high doses of vitamin C can help prevent blood platelet sticking and fight cholesterol oxidation. Also, researchers discovered this vitamin can reduce the formation of potentially carcinogenic nitrogen-containing compounds in the stomach, offering protection from stomach cancer, researchers have reported.
French and German researchers found that vitamin C appeared to keep cells in the blood vessel wall from dying. The researchers, who studied immune indicators, such as serum immunoglobulin and neutrophil phagocytosis (how well your white blood cells can engulf and digest foreign bodies), concluded that vitamin C exerts a remarkable immuno-modulating action, in other words, improved immune function in all those who consumed vitamin C on a regular basis.
What are deficiency symptoms for vitamin C?
Scurvy is a disease resulting from lack of vitamin C, since without this vitamin, the synthesized collagen is too unstable to perform its function. Scurvy was common among those with poor access to fresh fruit and vegetables, such as remote, isolated sailors and soldiers. The amount of vitamin C required to prevent “chronic disease” appears to be more than that required for prevention of scurvy which is 30 – 60 milligrams per day. Based on scientific research, vitamin C also appears to improve oral absorption of iron, which is good news for those that are anemic.
Half of us in the United States will die from heart disease. The foundation of heart disease is atherosclerosis, the narrowing of our arteries with plaque. Treatment with vitamin C has consistently resulted in improved dilation of blood vessels in individuals with atherosclerosis as well as those with angina pectoris, congestive heart failure, high cholesterol, and high blood pressure. Researchers believe this protection from cell death could explain previous study findings which suggest that vitamin C benefits blood vessel function in people with congestive heart failure.
Vitamin C supplements are also generally regarded as safe in most individuals in recommended amounts, although there are rarely reported side effects including nausea, vomiting, heartburn, abdominal cramps, and headache. In addition, this vitamin is required for the synthesis of l-Carnitine, a small amino acid that is essential for the transport of fat to cellular organelles called mitochondria, for conversion to energy. If you have chronic fatigue syndrome, vitamin C may help by boosting energy production through the mitochondria.
Therefore, as in many studies of vitamin C intake and cardiovascular disease risk, it is difficult to separate the effects of vitamin C on stroke risk from the effects of other components such as diet and the consumption of fruits and vegetables. As with all dietitians an emphasis on the benefits of a diet rich in fruits and vegetables is important to maintain a healthy cardiovascular system. If one can not consume fruits and vegetables on a daily basis then supplementation of vitamin C is need in either capsule of tablet to fight the risk of disease.
L-Carnitine For Health And Wellness
April 16, 2008 03:25 PM
Research continues to mount evidence that l-carnitine can help boost energy and quality of life. Carnitine comes from the Latin word for flesh: caro or carnis. L-carnitine was discovered and isolated from meat in the early 1900s. At that time, scientists thought that l-carnitine played a role in muscle function; this was many years before technology would advance so that this theory could be proved. Today, we know that this amino acid is found mostly in tissue of the body that requires lots of energy such as the heart, skeletal muscles, and liver.
L-carnitine is considered a non-essential amino acid since the body manufactures it from l-methionine and l-lysine. Depending on one’s diet, the body manufactures most of, not all, the l-carnitine it needs every day. There are circumstances where a rare genetic disease can cause the body to not manufacture its own l-carnitine resulting in a deficiency which can cause secondary diseases such as cirrhosis of the liver, chronic renal failure, diabetes, heart failure or Alzheimer’s disease. Some medications can cause a deficiency as well, check with your doctor about prescriptions.
The primary energy source for the body is long-chain fatty acids. L-carnitine plays an essential role in energy production process. This amino acid transports long-chain fatty acids into the mitochondria, where it is used to produce energy for each cell in the body. l-carnitine then removes the “acyl” group by products out of the mitochondria as they accumulate. Both the transporting in and out of the cells mitochondria is vital for continued muscle function to occur.
Researchers suggest that the limiting factor in high intensity exercise is from the availability of l-carnitine in the muscle tissue. Studies conducted with this amino acid suggest that athletes experience improved performance when supplementing with l-carnitine by reducing post exercise lactate acid levels and improving recovery from exercise stress.
Some research suggests that l-carnitine can help chronic fatigue individuals by shuttling long-chain fatty acids into the mitochondria where the body manufactures energy. The bulk of this research was done on chronic fatigue patients who consumed 2 grams per day of l-carnitine. Additional research was performed on individuals over 100 years of age and the results were these individuals experiences increase physical endurance and improved cognitive activity.
L-carnitine can help cardiovascular conditions including angina, congestive heart failure, and peripheral artery disease. Recent studies showed male fertility improvement when l-carnitine was consumed on a regular basis. Men participating had better sperm motility which increases the changes of one reaching an egg and improving the odds of fertilization.
Research also demonstrated that 1 gram of this amino acid daily over three months can help one reduce weight by improving fat metabolism. This holds consistent with the findings that l-carnitine transports long-chain fatty acids (fat) into cellular mitochondria so it can be burned as energy. With a good diet and exercise plan, reports suggest that even more weight loss can be achieved.
Safety is of particular concern when adding extra supplements to one’s diet such as l-carnitine. Good news, l-carnitine is very safe at 1 – 3 grams each day, even higher doses are safe with no side effects. With the mounting evidence on the benefits of l-carnitine consumption, what is stopping you from adding l-carnitine today to your supplement diet to improve health and wellness?
Ubiquinol Reduced CoQ10
April 07, 2008 01:05 PM
Ubiquinol, which is the reduced from of Coenzyme Q10 (CoQ10), has been recently added to the supplement offerings of many companies and has generated a lot of confusion along with its excitement. As a supplement, ubiquinol is somewhat new, but as a critical part of human metabolism, our knowledge of ubiquinol goes back to the discovery of CoQ10. Although CoQ10 is often thought of as a “static” nutrient in the context of nutrition, it actually interchanges between two useful states: the oxidized ubiquinone, and the reduced ubiquinol.
Coenzyme Q10 is a member of a family of important biological compounds which are referred to as ubiquinones. It is a lipophilic, water-insoluble substance, which takes part in a large array of biochemical oxidation and reduction reactions. It was first identified in 1957 as an essential component of the energy production system in cells. CoQ10 and other members of the ubiquinone family have, since then, been identified as critical metabolic compounds in a range of aerobic organisms. Because of its crucial role in metabolism, humans have the ability to make their own CoQ10, although small amounts can be obtained through diet and as supplements.
In humans, CoQ10 is found in each cell in the body, but is particularly abundant in tissues which have large energy requirements such as the heart, liver, kidneys, and skeletal muscles. Smaller amounts can be found in the brain, lungs, and intestines. There are also substantial amounts that can be found in circulation, which are most often associated with lipoprotein particles. In total, CoQ10 in a normal adult has been estimated to be between 0.5 and 1.5 grams. Inside cells, about half of the CoQ10 is found within the mitochondria, where the final steps of CoQ10 production occur.
CoQ10 which is not located in areas of the cell and are not charge with producing cellular energy can amount to about 50-60 percent of the total CoQ10 pool. CoQ10 can be found throughout cell membranes and in other cellular structures such as the nucleus, cytoplasm, and endoplasmic reticulum. Some experimentation has also concluded that, while the final steps of CoQ10 production occur in the mitochondria, it can be exported to other sub-cellular locations.
While participating in various oxidation and reduction reactions, CoQ10 is cycled between two stable states: a fully oxidized form referred to as ubiquinone, and a fully reduced form called ubiquinol. CoQ10 cycles through these oxidated/reduced forms in order to achieve its metabolic goals. The cycle of CoQ10 is simple. Ubiquinone picks up electrons and then becomes ubiquinol. Ubiquinol then release its electrons and becomes ubiquinone again. Therefore, it would seem that CoQ10 has a very simple function of moving electrons, as the transfer of electrons is a fundamental step in the production of energy, the regeneration of antioxidants in cell membranes, and the construction of other important biological molecules. Each cell that is in the body needs a source of energy in order to survive. Therefore, sugars, fats, and amino acids are broken down in order to make energy.
In the mitochondria, CoQ10 is abundant, as it carries electrons to aid in the chemical reactions that burn cellular fuel and produce chemical energy to form ATP. Since substantial amounts of ATP are needed to power our cells, the importance of CoQ10 in human metabolism is easily understood. Both forms of CoQ10 are needed to transfer electrons between energy-producing reactions. Outside of the mitochondria, CoQ10 performs a slightly different role as a membrane and antioxidant. About half of the human body’s total CoQ10 pool may be functioning in this capacity. CoQ10 is one of the major antioxidant elements of the LDL particles and is also one of the first to be depleted when LDL is subjected to oxidation.
A discussion of CoQ10 would not be complete without mentioning its documented health benefits. Supplemental CoQ10 has been the subject of a lot of studies over the last half century, especially in applications for cardiovascular health. Many studies have shown benefits of CoQ10 in patients who are diagnosed with chronic heart failure, exercise-induced angina, hypertension, or those who have recently experienced infarction. There is also early evidence showing that CoQ10 may protect the heart from damage during chemotherapy, bypass surgery, or in diabetes. Aside from its cardiovascular uses, CoQ10 has been studied for its benefits in other conditions involving dysfunctions in cellular energetics, neurological degeneration, or oxidative stress damage. Although the clinical evidence for the potential benefit of CoQ10 in many of these applications shows promise, the variability in study outcomes proves it necessary to further research these areas for a more definite answer.
As we have previously seen, CoQ10 functions by cycling between two stable forms, ubiquinol and ubiquinone. This cycle results in the generation of cellular energy and the protection of membranes and lipids from oxidation. Dietary or supplemental CoQ10 also takes part in this cycle. Supplemental ubiquinol may have a distinct advantage over ubiquinone in its facility of absorption. Like many fats and lipophilic nutrients, CoQ10 is usually taken up by the intestinal electrolytes, packaged into lipid particles, and then released into the lymphatic system. From there, these particles are transferred into circulation where they are free to be transported throughout the body as needed.
The absorption of dietary CoQ10 is actually quite poor since it has limited solubility in lipids and depends on other contents of the gut. Some studies have measured that absorption is as low as 2-3 percent of the total dosage. One of the most thrilling consequences of the development of a stabilized dosage form of ubiquinol is its ability to be absorbed more efficiently than ubiquinone. There is evidence that CoQ10 must be reduced in intestinal enterocytes before the release into the lymphatic system. This, paired with absorption/reduction, may be a rate-limiting step of CoQ10 assimilation.
Dietary ubiquinol avoids this reduction reaction, and is directly available for absorption, which explains why ubiquinol-based CoQ10 supplements exhibit enhanced bioavailability over ubiquinone supplements. Preliminary studies in humans have shown that absorption of ubiquinol is at least double the absorption of ubiquinone. Comparisons of blood levels between trials also estimate the improvement in absorption to be significantly higher. Future studies are necessary to more accurately determine ubiquinol’s enhanced absorption, and what effect the patient age or medical condition may have on these results.
Fat Controls our hunger centers in the brain!
April 04, 2008 11:28 AM
The main cause of any chronic disease of aging including Type II diabetes, CV disease, obesity, osteoporosis, and cancer are all caused by miss communication between signals that tell your body how to turn energy into life and the brain. The two most important signals that we know of today are given by the hormones insulin and leptin.
Leptin is an extremely powerful and influential hormone that is produced by fat cells. It has totally changed the way scientific researchers look at fat, nutrition, and metabolism in general. Before leptin’s discovery in 1994, fat was regarded as strictly an ugly energy store that most everyone was trying to get rid of. However, after it was discovered that leptin is actually produced by fat, fat became an endocrine organ similar to the ovaries, pancreas, and pituitary, as it influences the rest of the body, especially the brain.
Leptin is the most powerful regulator known to date of eating and reproduction. Your fat tells your brain whether you should be hungry or eat and make more fat, whether you should reproduce and make babies, or whether to maintain and repair yourself. It can then be stated that instead of your brain being in control of your body, your body, especially its fat and leptin, controls your brain.
Throughout history, it has been in ones best interest to store some fat to call upon during times of famine. However, it is also just as bad to be too fat. For most of our history, it was necessary to run, hunt, and avoid being prey. Therefore, fat storage had to be highly regulated and it still is. When a person typically tries to lose weight, the body tries to gain it back, resulting in what is commonly known as yo-yo dieting. Because of this, it has long been theorized that there is a “set point” and there must be a hormone that determines this.
Science now believes that leptin is that hormone. So in order to break the yo-yo cycle, one must control leptin. If a person is getting too fat, the extra fat produces more leptin that is suppose to tell the brain there is too much fat stored and the excess should be burned. Signals are then sent to the hypothalamus to stop being hungry, stop eating, stop storing fat, and start burning off some extra fat. Controlling hunger is a major way that leptin controls energy storage. Hunger is a very powerful drive that will make you do all you can to eat if it is stimulated long enough.
The only way to eat less in the long-term is to not be hungry and the only way to do this is to control the hormones that regulate hunger. The primary hormone that does this is leptin. It has recently been found that leptin not only changes brain chemistry, but can also rewire the neurons in areas of the brain that control hunger and metabolism to do its bidding. The inability of the body to hear leptin’s signals plays significant and even primary roles in heart disease, obesity, diabetes, osteoporosis, autoimmune diseases, reproductive disorders, cancer, and even the rate of aging itself.
In a process called glycation, glucose reacts with protein which results in sticky, sugar-damaged proteins called advanced glycated end products, or AGEs for short. When protein is damaged, it can’t function or communicate properly. AGEs promote excessive inflammation and free radical damage. AGEs and free radicals from oxidation are two of the major molecular mechanisms that cause damage which leads to aging. AGEs cause skin and the lining of arteries to wrinkle and inflame, which contributes to plaque and heart attacks. They can also promote the formation of cataracts and macular degeneration leading eventually to blindness.
The glycation process has also been connected with the destruction of proteins and nerve cells that may lead to Alzheimer’s disease, memory loss, and a variety of neuropathies. Glycation and oxidation are two of the major molecular mechanisms where damage accrues, disease occurs, and death results. High blood sugar can suppress your immune system, making you more vulnerable to infection and cancer. Highly aggressive cancers outpace the availability of oxygen and therefore must use an anaerobic fuel, in the form of glucose. By consuming glucose (sugar), we feed cancer. Lastly, high blood levels of sugar form non-fiber carbohydrates and excess protein send leptin and insulin levels upward.
If there is a known marker for long life, it is low insulin levels. Insulin’s purpose is not only to regulate blood sugar, but to store excess energy for future times of need. Insulin also lowers blood glucose levels as a side effect from storing it away, not regulating it. Today, high glucose is quite normal, as our insulin levels are typically much higher than they were among our ancestors. When you are constantly bombarding your cells with insulin, they become insulin resistant. This causes insulin levels to rise, creating a hormonal derangement that has a catastrophic effect on the metabolism.
High insulin contributes to making you fat because it tells your cells to store nutrients as fat rather than to burn it. Repeated high levels of insulin cause insulin resistance. The more fat the body accumulates the more leptin the body can produce so fat works against to slow down insulin production causing insulin resistance..
High insulin causes the retention of sodium, fluid retention, excretion of magnesium, elevated blood pressure, cognitive heart failure, blood clotting, and arterial plaque formation. Heart attacks are much more likely to happen after a meal that is high in carbohydrates than after one that is high in fat. This triggers a stress response which can cause arterial spasm, constriction of arteries, elevated blood pressure, irregular heartbeat and sudden death. Insulin resistance along with low magnesium keeps you from metabolizing important fatty acids that are vital to your heart health in general.
As critical as insulin is in your health, leptin may even be more so. Leptin plays a significant role in obesity, heart disease, osteoporosis, autoimmune diseases, inflammatory diseases, and cancer. But there are clues as to how to live a long and healthy life which brings us back to fat and leptin and our need to control it. One can control their insulin production and fat by dietary changes and blood sugar supplements.
B Complex to Restore the Adrenal Glands from Stress
February 07, 2008 05:18 PM
The B vitamins comprise a range of water soluble vitamins that frequently work together to impart a number of general benefits to your body’s health. In general they support and maintain the metabolic rate, maintain the function of the nervous system, support the immune system, maintain healthy skin and muscles and help to promote cell growth and division. They work together to suppress the causes and symptoms of cardiovascular disease and stress and they are dispersed throughout the whole of the body by means of the circulation system of the blood.
In very general terms they collectively ensure that the body is provided with energy from the metabolism of carbohydrates and glucose. They are also needed for the metabolism of fats and proteins, and also the maintenance and health of the nervous system in general.
There are many natural sources, including lentils, potatoes, liver, turkey, brewer’s yeast, and also, of course, dietary supplements.
Vitamin B Complex can help to restore the adrenal glands from stress, but to understand how it does so, it is first necessary to understand what these glands are, and the part that they can play in stress.
The adrenal glands are situated just above each kidney, and take the form of two small pieces of tissue in the shape of a pyramid that generate specific hormones and chemical messengers. You have likely heard of adrenaline, the hormone that make you respond to certain types of stress either through flight or by fighting: what is known as the fight or flight reaction. Well, in fact there are two of them, noredrenaline being the other. They are also known as epinephrine and norepinephrine respectively.
Both the adrenal glands are controlled by what is known as the HPA axis, short for the hypothalamus-pituitary-adrenal axis which is the stress center of the body. The adrenals are the main steroid-producing plants in the body, responsible not only for the adrenaline hormones, but also for cortisone and hydrocortisone, testosterone, estrogen, cholesterol, progesterone and a number of others. These are produced in the outer cortex of the adrenal glands, whereas adrenaline and noradrenaline are produced and secreted by the medulla.
Adrenaline and cortisol are responsible along with others for the balance of your body fluids, blood sugar and blood pressure and many of the other main metabolic functions of the body, and if the adrenaline is not working properly, it can disrupt the metabolism of your blood glucose into energy, giving you a weak run-down and listless feeling. This is not surprising since your energy is failing at the cellular level.
The main reason for adrenal fatigue is stress. Either emotional or physical stress or even poor nutrition can be responsible for reducing the functioning of the glands to such an extent that they no longer provide the steroid hormones in the proper balanced quantities needed to maintain the proper functioning of your metabolic processes. Unlike Addison’s disease, which a complete stoppage of the functioning of the adrenal glands, in Adrenal Fatigue Syndrome the glands still function, but at a reduced capacity and the various products they are responsible for generating are secreted in reduced and imbalanced quantities.
However, fatigue is not normally the first reaction of the body to stress. As normal stress levels increase the bodies response is generally to secrete higher levels of adrenaline, and the cortex produces extra cortisol and other hormones. As stress continues beyond the intermittent stage and becomes more constant, the adrenals produce a more sustained high level of hormones, that generally raise blood pressure and also increase the level of sugar in the blood in order allow a sustained increase in energy levels. Corticosteroids are produced to maintain this higher level reaction to stress.
Finally, when the adrenals can sustain this high level of activity no longer, adrenal fatigue sets in which is when the worst symptoms of the stress are evident: exhaustion, both physically and mentally, excessive fear, guilt and worry, and under-activity of the HPA axis leads to depression, hopelessness and severe illness, often due to a weakened immune system.
So where does the B vitamin complex come into this? Vitamin B complex includes niacin, thiamine, pantothenic acid, riboflavin, and vitamins B6 and B12. As already stated, the complex is useful in supporting many of the critical functions of the body from healthy bones to healthy blood cells, and nervous systems. It also helps to maintain your reproductive system and can be used in cases of nerve-related conditions such as sciatica and neurological conditions.
Pantothenic acid, vitamin B5, is particularly useful in dealing with stress in that it enhances the activity of the adrenal glands. It also increases your energy levels due to its effect on the Krebs Cycle through its action as a precursor of acetyl Coenzyme A and acetylcholine which is a primary neurotransmitter. This helps to reduce fatigue and the pain of headaches caused by excessive stress and consequent reduction in adrenal output. Pantothenic acid is also essential during the metabolism of proteins, fats and carbohydrates, and is important in the maintenance of healthy nerves, skin and glands.
In fact the whole of the vitamin B family work together to make sure that your whole nervous system and metabolism remain healthy. People with high stress jobs often take the vitamin B complex to help reduce that stress and also anger. Excessive stress and anger can lead to anxiety and overwork the adrenal glands, and B complex can help to restore these to their normal function.
If you are concerned about your adrenal health, you can have a simple test carried out on your saliva, blood or urine by a trained medical practitioner. Many doctors do not know to carry out this test since it is not a normal test as would be used to detect Addison’s Disease, or complete adrenal failure, but only adrenal fatigue, so ask specifically for an adrenal fatigue check.
A quick self-test is to shine a light into an eye using a flashlight while looking in a mirror. They pupil should contract and return to normal after about 30 seconds. If it fails to do so, or even dilates, then that is a sign of adrenal fatigue. However, you must have it confirmed by a proper test.
All in all, a B complex supplement is a good way to restore adrenal glands from stress, and it also helps your nervous system in general, in addition to aiding the metabolic processes of your body. However, make sure that your symptoms are what you think they are by seeking professional medical advice.
Regulating Blood Pressure Naturally
March 28, 2007 10:29 AM
Regulating Blood Pressure Naturally
High blood pressure (also known as hypertension) affects about 65 million Americans, or about 1 in 3 adults. There are many potential causes of hypertension, but not necessarily any symptoms. In fact, 30% of the people who have high blood pressure don’t even realize it.
In other words, just because you don’t have symptoms doesn’t mean you don’t have high blood pressure. That’s why it’s called “The Silent Killer.” And, make no mistake about it: high blood pressure is dangerous. It is the number one modifiable cause of stroke. Just lowering blood pressure reduces the chance of stroke by 35 to 40 percent. Other conditions, including heart attack and heart failure can be reduced from 25 to 50 percent, respectively.
In this issue of Ask the Doctor, we’re going to talk about high blood pressure and an exciting natural treatment for lowering blood pressure safely and effectively.
Of course, changing blood pressure numbers depends, in a large part, on the choices we make every day – how much we exercise, the foods we eat, and our lifestyle overall. But, for those times we need extra help, there is a new, scientifically-studied supplement to help us along our path to better health and lower blood pressure.
Blood pressure guidelines from the National Heart, Lung, and Blood Institute.
Q. What exactly is blood pressure?
A. Blood pressure is divided into two parts, systolic and diastolic. Systolic is the pressure of the heart beating. Diastolic is the pressure of the heart and vessels filling. When blood pressure numbers are written out, like “120/80,” 120 is the systolic pressure and 80 is the diastolic pressure. The unit of measurement for blood pressure is millimeters of mercury, written as “mm/Hg.”
Q. What is considered high blood pressure?
A. A person’s blood pressure can naturally vary throughout the day – even between heartbeats.
However, if the numbers are consistently high (over 120 systolic and 80 diastolic), after multiple visits to your healthcare practitioner, you may have either pre-hypertension or high blood pressure.
Young arteries and arteries that are kept young through healthy diet and exercise are typically more elastic and unclogged. Blood flows through them easily and without much effort. However, as we age, our arteries become more prone to plaque buildup (due to diets high in saturated fat and sedentary lifestyles) and don’t “flex” as well under pressure. The result is faster blood flow, all the time. Over the long term, it damages heart tissue, arteries, kidney and other major organs.
To get a better idea of high blood pressure, compare your arteries to a garden hose. When unblocked, a garden hose allows water to flow through it quickly and easily – without any real rush or stress. However, if you block the end of the hose with your thumb, closing it off even a little, water rushes out much more quickly.
For many years, high diastolic pressure was considered even more of a threat than high systolic pressure. That thinking has changed somewhat but high diastolic numbers could still mean organ damage in your body – especially for individuals under 50.
Q. What courses high blood pressure?
A. The reasons for hypertension aren’t always clear. However, there are lifestyle factors that contribute to high blood pressure that you can change:
Body type: Weight isn’t always a reliable indicator of whether or not you’ll have high blood pressure – but the type of weight is. Lean body mass – muscle – doesn’t increase blood pressure levels the way that fat can. However, fat body mass, especially fat around your middle, can contribute to high blood pressure.
Sedentary lifestyle: Too often, many of us sit down all day at work, and then sit down all night at home. Over time, this inactivity usually leads to weight gain, making the heart work harder to pump blood through the body. In a way, it almost seems contradictory, but inactivity usually leads to higher heart rates.
Sodium intake: Sometimes it’s hard to believe how much salt there is in processed foods. However, salt intake in itself is not necessarily bad. For people with a history of congestive heart failure, ischemia, and high blood pressure, sodium is definitely out. For those individuals, it leads to more water retention, which increases blood pressure. (Salt’s effect on water retention is one reason that so many sports drinks have fairly high sodium content – the sodium in the drink prevents your body from sweating out too much water.) But, for healthy individuals, moderate salt intake, especially a mixed mineral salt like sea salt or Celtic salt (good salt should never be white) is fine.
Low potassium intake: Unlike sodium, potassium is a mineral which most Americans get too little of. Potassium helps regulate the amount of sodium in our cells, expelling excess amounts through the kidneys. Low levels of this mineral can allow too much sodium to build up in the body.
Heavy alcohol intake: Having three or more alcoholic drinks a day (two or more for women) nearly doubles an individual’s chance of developing high blood pressure. Over time, heavy drinking puts a lot of stress on the organs, including the heart, liver, pancreas and brain.
Unhealthy eating: Eating a lot of processed or fatty foods contributes to high blood pressure. Adapting a diet that is rich in fruits and vegetables, whole grain products, fish, nuts and magnesium and potassium (like the Dietary Approaches to Stop Hypertension, known as the “DASH” diet) can bring it back down.
Smoking: If you smoke, stop. Smoking damages the heart and arteries – period. Nicotine constricts blood vessels, increases heart rate, and raises blood pressure. This in turn, increases hormone production and adrenaline levels, further stressing the body.
As if that weren’t bad enough, the carbon monoxide in cigarette smoke replaces the oxygen in the blood, making the heart work even harder to make up the difference. Since the effect of a single cigarette can last for an hour, smoking throughout the day leads to continuously revved-up blood pressure.
Some of these factors might sound like a lot to overcome. The important thing to remember is that all of these behaviors are changeable. If you have high blood pressure, modifying any of these can significantly lower blood pressure as part of an overall plan.
Q. What are the blood pressure numbers I should see?
A. Experts consider healthy blood pressure numbers to be 115/75 mm/Hg. The reason? They found that the risk of cardiovascular disease doubles at each increment of 20/10 mmHg over 115/75 mm/Hg. Even small jumps in blood pressure numbers increase the risk of stroke and heart attack.
Q. Okay, so other than diet, exercise and lifestyle changes are there other natural ways or supplements I can use to lower my blood pressure?
A. Yes, in fact, you hear about some of them in the news all the time – fish oil, CoQ10, and garlic. As effective as these symptoms are, they typically lower systolic pressure much more than diastolic pressure.
However, there is a blend of scientifically and clinically studied natural ingredients that lower high blood pressure separately, and work even better when they’re combined. This combination blend contains: dandelion leaf extract, lycopene, stevia extract, olive leaf extract and hawthorn extract.
Every one of these ingredients has been studied and recommended for years. But now, a scientific study on a supplement that combines them in one synergistic formula shows encouraging results for lowering systolic and diastolic blood pressure.
Let’s take a look at each:
Stevia (Stevia rebaudiana) originated in
The leaf of stevia is considered the medicinal part of the plant. Research shows that extracts of the leaf relax arteries and help prevent the buildup of calcium on artery walls – keeping them healthy and reducing blood pressure.
In a long-term, randomized, placebo-controlled clinical study, stevia reduced systolic and diastolic blood pressure. On average, participants’ blood pressure reduced from baseline 150 mm/Hg to 140 mm/Hg systolic and 95 mm/Hg to 89 mm/Hg diastolic.
And, in another double-blind, placebo-controlled clinical study, stevia lowered blood pressure quite significantly – by an average of 14 millimeters of mercury in both systolic and diastolic readings. Those are impressive numbers!
Despite its role as a sweetener, stevia may have a side benefit to for those with hypertension – blood sugar regulation. Scientific studies show that extracts of stevia regulated blood sugar and reduced blood pressure.
A clinical study showed that stevia extract actually improved glucose tolerance by decreasing plasma glucose levels during the test and after overnight fasting in all participants. Regulating blood sugar is very important for those with high blood pressure. When blood sugar levels are high, blood vessels are inflamed. Many people with diabetes have high blood pressure as well. In a paired, cross-over clinical study, stevioside (one of the compounds in stevia) reduced glucose levels in individuals with type 2 diabetes. Further scientific studies show that stevia works to control blood sugar levels by stimulating insulin secretion by the pancreatic beta cells. It shows great potential in treating type 2 diabetes. Further scientific studies show that stevia works to control blood sugar levels by stimulating insulin secretion by the pancreatic beta cells. Its shows great potential in treating type 2 diabetes as well as hypertension.
Hawthorn (Crataegus spp. Oxycantha) has been used since ancient ties as a medicinal herb – even being mentioned by the Greek herbalist Dioscorides, in the first century AD. Traditionally, it has generally been used for support of the heart. Modern research points to bioflavonoid-like complexes in hawthorn leaf and flower that seem to be most responsible for its benefits on cardiac health, like blood vessel elasticity.
The bioflavonoids found in hawthorn include oligomeric procyanidins, vitexin, quercetin, and hyperoside. They have numerous benefits on the cardiovascular system. Hawthorn can improve coronary artery blood flow and the contractions of the heart muscle. Scientific studies show that the procyanidins in hawthorn are responsible for its ability to make the aorta and other blood vessels more flexible and relaxed, so that blood pumps more slowly and with less effort – sparing the cardiovascular system such a hard workout.
The procyanidins in hawthorn also have antioxidant properties – protecting against free radical cellular damage.
And, hawthorn may also inhibit angiotensin-converting enzyme. Angiotensin-converting enzyme is responsible for retaining sodium and water, and may have roots in our evolutionary development. It influences blood vessel contraction and dilation, sodium and water balance and heart cell development – just about everything that has to do with blood pressure. This may have developed as a way of dealing with periods of drought and stress. By narrowing the blood vessels, the body could guarantee an adequate supply of blood and focus on repairing tissue.
Unfortunately, that can lead to real problems these days. Since many of us live in an industrialized society, and frequently have pretty sedentary lifestyles, conserving sodium just makes the conditions for high blood pressure that much worse.
Like the other ingredients in this combination, hawthorn showed benefits on other body systems, too. In clinical and scientific studies, it not only lowered blood pressure, but also showed anti-anxiety properties and regulated blood sugar.
Olive leaf extract:
Olive leaf (Olea europaea) comes up again and again in scientific and clinical studies as having beneficial effects on hypertension. One of olive leaf’s most beneficial compounds is oleuropein – the same compound that makes olive oil so helpful in reducing blood pressure. Here again, we have to look at the traditional Mediterranean diet, which features voluminous use of olives and olive oil. Not surprisingly, blood pressure is generally much lower in Greek and Italian populations.
But it’s not just the diet – scientific studies showed that oleuropein lowered blood pressure by relaxing the blood vessels and prevented buildup of plaque in arteries. Plus, whether in olive leaf extract or in olive oil, oleuropein works as an antioxidant, too.
Dandelion leaf extract:
Dandelion (Taraxacum offinale) leaves provide a healthy supply of vitamins, much like spinach. In fact, although it has become the bane of North American gardeners and lawn owners, dandelion greens are a component of many gourmet salads.
Medicinally, dandelion has been used for centuries, dating back to ancient
They are a very rich source of vitamin A, and contain vitamin D, vitamin C, carious B vitamins, iron, silicon, magnesium, zinc and manganese, too. Dandelion leaves produce a diuretic effect in the body, similar to a prescription drug. Since one of dandelion leaf’s traditional uses was the treatment of water retention, it’s really not too surprising. Dandelion leaf is also rich in potassium – one of the vital minerals many Americans lack in their diet. So, even though it may act as a diuretic, it replaces more potassium than the body expels.
The diuretic effect of dandelion can relieve hypertension by drawing excess water and sodium from the body and releasing it through the kidneys as urine. Getting rid of extra water and sodium allows the blood vessels to relax – lowering blood pressure.
If a nutrient can be called exciting, lycopene is it. Lycopene is found mostly in tomatoes and processed tomato products, like pasta and pizza sauce. Related to beta-carotene lycopene shows great antioxidant abilities among its many talents. In fact, it shows even greater free-radical scavenging properties than beta-carotene, its more famous cousin. Healthy intakes of lycopene can guard against a variety of chronic conditions, including lowering LDL (bad) cholesterol, lowering homocysteine levels and reducing blood platelet stickiness that can lead to clogged arteries. It’s even being studied for its protective effect against prostate cancer.
And, for proof, you don’t have to look too far to see the amazing effect lycopene intake can have on health. The Mediterranean diet provides an excellent example. Its high intakes of vegetables, (tomatoes, of course, playing a central role) fish, and whole grains improve cholesterol levels and lower blood pressure. The research on lycopene as a stand-alone nutrient has been compelling. A randomized clinical trial found that not having enough lycopene was associated with early thickening of the arteries.
So, it makes sense that other clinical trials, showed that higher intakes of lycopene frequently meant less thickening of arteries, and a reduced risk of heart attack. In one study, the risk of heart attack was 60% lower in individuals with the highest levels of lycopene. In a multicenter study, similar results were found – men with the highest levels of lycopene had a 48% lower risk of heart attack.
Q. What can I expect taking this herbal combination?
A. You should notice both systolic and diastolic numbers lowering in about two weeks. The scientific study showed that for pre-hypertensive and stage I, (early hypertensive individuals) this combination for ingredients lowers both systolic and diastolic blood pressure.
When you’re taking herbs to support your blood pressure, it’s important to keep it monitored so you have an accurate reading (and record) of your numbers. If you need to, you can pick up a home blood pressure monitoring device. These can retail for anywhere from $30 all the way up to $200, but buying one in the $30 to $50 range is a good idea and money well spent. Consider taking the machine to your local doctor’s office or fire department to have it tested for accuracy against a professional blood pressure monitor. See the chart below for tips on getting an accurate reading from a home monitor.
Tips for Accurate Blood Pressure Monitoring:
-Relax for about 5 to 10 minutes before measurement.
-If you have just come inside from cold outdoors allow yourself to warm up.
-Remove tight-fitting clothing and jewelry.
-Unless your physician recommends otherwise, use left arm to measure pressure.
-Sit, don’t stand.
-Remain still and do not talk while using the monitor.
Q. Are there any side effects?
A. There were no side effects noted in the study. However, because of the mild diuretic effect of dandelion leaf extract, you may notice an increase in trips to the bathroom. It’s always important to make sure you don’t get dehydrated, so you may want to drink more water during the day.
High blood pressure doesn’t happen overnight. As we get older, the likelihood of developing hypertension increases. And, stressful, fast-forward lifestyles, bad diets and no exercise conspire to raise our blood pressure.
In my own practice I have helped patients move toward a healthier lifestyle, including diet, exercise, and blood-pressure reducing supplements. They live better, more vibrant lives as a result, and their blood pressure normalizes. It really can happen – you can bring your blood pressure back to normal, and this combination of scientifically and clinically validated ingredients can help.
For Better Heart Health ...
February 06, 2007 12:57 PM
Nutrients Every Heart Needs
High blood pressure. High cholesterol levels. Ever increasing stress. All are factors related to the development of heart disease – the leading cause of death for both men and women. In fact, 1 in 2 women in the
Fortunately, heart disease is a problem you can do something about. Proven ways to prevent or mitigate the effects of heart disease include taking targeted nutritional supplements, making changes in the foods we eat, exercising most days of the week, drinking in moderation, eliminating tobacco use and adapting a positive attitude. Research shows that those of us who are often angry and depressed have more heart disease than people that live their lives with a more positive outlook.
In this Ask the Doctor, we’ll talk about specific nutritional supplements that are heart healthy, whether your goal is to prevent heart disease or reduce the effects of heart disease if you currently have it.
Q. I am trying hard to live a healthier life. But it all seems so overwhelming. How do I start?
A. It may help to know that you’re not alone in feeling overwhelmed. Lots of people feel this way. This is why the Centers for Disease Control and the American Heart Association are both urging people to prevent heart disease by identifying their individual health risk factors.
A risk factor is an indicator of whether or not you may develop a certain health condition. In heart disease prevention, there are two kinds of risk factors. There are risk factor you can control – such as diet, exercise, and the supplements you take. There are also risk factors you can’t change or control –your age, race, and gender, as well as your family’s history of heart disease.
Examples can be really helpful. Let’s follow three adults – Fred, Jane, and Earl – and determine their risk factors.
Fred is 32, single, has a job he loves, has an optimistic attitude about his life, and works out 5 days a week. Most days Fred’s diet is fruits, vegetables, whole grains and low fat. Occasionally Fred will eat a cheeseburger and fries when he watches the game with his buddies. Fred’s risk factors are his male gender and the occasional high fat content in his diet.
Jane is 55, a lawyer, married, and has a very stressful job. Jane eats lots of salads, fruits, and whole grains. However, her job requires her to work long hours which leaves little time to exercise. Jane is for the most part happy with her life, but her work stress had led to times of negativity. Her father had a heart attack when he was 56. Jane’s risk factors include her age (greater than 50), negativity from job stress, lack of regular exercise, and a family history of heart disease.
Earl is 65, married, and has just retired from a job he hated. He spends most of his day watching TV and eating potato chips and other high fat, salty snacks. Earl has told his friends and family since he worked so hard for so long, he is sure to drop dead soon after retiring. He has high cholesterol and high blood pressure. Earl’s father had a heart attack and died when he was 73. Earl’s risk is his male gender, age (greater than 50), sedentary lifestyle, poor diet, negative outlook on life, high cholesterol and high blood pressure, and a family history of heart disease.
Q. OK, it’s pretty easy to see that Fred needs to watch his diet, Jane needs to exercise more, and Earl needs lots of help. But, which supplements should they take?
A. The Whole Heart Nutrition chart is an easy way to determine the supplements each risk level needs. As you can see, everyone wanting to prevent heart disease – Fred, Jane, Earl, you, and I – need to take quality heart formula multivitamin, garlic, and a fish oil supplement providing Omega-3 fatty acids. CoQ10 is also a smart choice for complete heart heath support.
Q. Why do we all need to take a “heart multivitamin”? Why can’t we take a regular multivitamin to prevent heart disease?
A. Since the human heart simply cannot function without adequate amounts of certain vitamins and minerals, it seems logical that a multivitamin would be the foundation of good nutrition for your heart. Heart-health formulated multivitamins provide the exact nutrients needed to prevent heart disease.
That’s why we need to take a specially formulated heart-focused multi-vitamin. The cells and the tissues that make up the heart must have vitamins C, A, and E, as well as B1, B6, and B12 to function. Folic acid, the little B vitamin that is so crucial in preventing spina bifida (a birth defect), breast cancer, and Alzheimer’s disease is also needed to keep heart muscles strong. The B vitamins and folic acid are very important to heart health because they help lower homocysteine levels. Homocysteine is a potential and emerging cardiac risk factor,
Magnesium is a mighty mineral and healthy hearts need it every day. Aloha lipoic acid, a fatty acid, provides protection against heart cholesterol and high blood pressure. Lutein and lycopene are all-natural nutrients and keep our arteries free from the buildup of plaque, a condition linked to heart attacks and strokes.
Multivitamins formulated with these exact vitamins, minerals, and nutrients will work with medications often prescribed to treat heart disease and provide the nutrition our hearts need.
Q. Don’t all multivitamins work with medications prescribed to treat heart disease?
A. Many multivitamin formulas contain herbs and other nutrients that can interfere with prescription medications, especially mediations prescribed to treat heart disease. One multivitamin does not fit all.
The more risk factors you have, the greater your chance of developing heart disease.
Q. What can garlic supplements do for Fred, Jane and Earl or other people with low to high risk factors?
A. Garlic supplements have a very long and very successful history of preventing premature death from heart attacks. Lately, however, there have been some conflicting news stories about supplemental garlic’s ability to lower high cholesterol and high blood pressure – the causes of heart disease and death. That’s because many different garlic supplements have been used in these studies – garlic oil, garlic powder, aged garlic extract, and supplements made from fresh garlic. They have all been studied clinically for their effects in heart disease.
The best garlic supplements (and the ones that showed the best effects in garlic studies) contain alliin, which is then converted to allicin. Allicin is the compound that lowers harmfully high cholesterol levels and dangerous blood pressure readings. Allicin is also responsible for garlic’s characteristic odor. Because alliin is very stable when dry, properly prepared and enteric coated fresh garlic preparations preserve the allicin-producing action until the garlic mixes with the fluids of the intestinal tract. Fresh garlic extract’s enteric coating also prevents garlic breath. In contrast, aged garlic contains absolutely no allicin or allicin potential. This fact is probably responsible for the poor results noted in lowering cholesterol and blood pressure from aged garlic preparations.
The most effective garlic supplements are made from fresh garlic, enteric coated, and provide a daily dose of at least 10 milligrams (mg) alliin or a total allicin potential of 4,000 micrograms (mcg). Taking a once-daily garlic supplement that delivers 4,000 mcg of allicin will lower Jane’s and Earl’s high blood pressure and Earl’s high cholesterol, naturally and effectively.
Whole Heart Nutrition
Each additional risk factor requires additional supplements or increased doses for protection from heart disease.
Q. What about fish oil supplements? I know they can prevent heart disease but I’ve also heard they contain harmful substances, too.
A. You’re right on both counts. But, there are excellent fish oil supplements naturally loaded with Omega-3 fatty acids, powerful nutrients that prevent heart disease, that are also certified free of harmful contaminants.
In the 1980s, researchers first began noticing the native Inuit (Eskimo) populations of Greenland and
Research has shown that the Omega-3 fatty acids in fish oil supplements can:
-Reduce the risk of arrhythmias, lethal heartbeat rhythms that cause sudden death.
-Lower the levels of triglycerides, fats in the blood that can increase a person’s
risk of dying from a heart attack, even if a person’s cholesterol levels are normal.
-Slow atherosclerosis – the growth of harmful plaque on artery walls.
Atherosclerosis develops over many years. If the plaque growth is slow and
stable, chances are low that a heart attack will result. However, rapidly growing
or unstable plaques can rupture. The body responds with inflammation, which
causes blood clots to form. These blood clots block the artery and cause a heart
-Keep blood pressure levels low. Many people have high blood pressure for years
without knowing it. That’s because it has no symptoms. Uncontrolled high
blood pressure can lead to stroke, heart attack, heart failure, and kidney failure.
While 25% of Americans have high blood pressure, nearly one-third of these
people don’t know they have it. This is why high blood pressure is often called
the “silent killer.”
You can get all of this heart disease preventive protection from just 600-1800 mg of fish oil. It’s pretty simple to see why Fred, Jane, Earl, and you and I need to take fish oil supplements every day.
However, it is absolutely critical that the fish oil supplement you take is free of contaminants and guaranteed fresh! Make sure that the manufacturer of the fish oil supplement you buy is able to provide documentation of purity in their product. Supplements should contain no detectable dioxin (a widely used toxic preservative), DDT (a toxic insecticide), PCBs (polychlorinated biphenyls) or heavy metals such as mercury and lead.
Before you buy any fish oil supplement, ask the clerk if you can open the bottle or jar and smell the contents. A fishy smelling fish oil supplementation means it is rancid. Rancid fish oil is not going to help your heart at all and may actually hurt it.
Q. That leaves CoQ10. Why is it important for Jane and Earl?
A. CoQ10, also known as ubiquinone, is the premier heart supplement! CoQ10 is part of our energy producing system. It works directly in the mitochondria of each cell. Mitochondria are highly specialized structures within each cell and are often referred to as powerhouses. These tiny energy producers generate 95% of the energy the body requires. The number of mitochondria in a cell depends on its function and energy needs. The heart has very important functions and requires a vast amount of energy. Thus, the heart has a lot of mitochondria or little powerhouses.
CoQ10 is incredibly crucial to the health of our hearts. Especially to hearts that are pumping blood with too much cholesterol. But, in a dangerous paradox, CoQ10 levels can become dangerously depleted when physicians treat high cholesterol in their patients with certain medications. The so-called “statin” drugs (Mevacor/lovastatin and Crestor/rosubastatin are two examples) are powerful and medications prescribed to lower harmful cholesterol levels. However, one very harmful side effect they share is that they deprive cells of CoQ10. While some physicians are aware of this serious side effect and tell their patients to take at least 400 mg of CoQ10 each day, most are not. The result? Any good the statin drugs may be doing is actually negated by their depletion of CoQ10.
Q. How does CoQ10 actually work? Has it been studied in heart disease?
A. Yes, it has! CoQ10 has been extensively studied in heart disease. This natural nutrient is present in every nucleated cell in our body (the only cells that don’t contain CoQ10 are red blood cells). Heart cells, however, are absolutely loaded with CoQ10. Its job is fairly simply – CoQ10 is vital to the production of adenosine triphosphate (ATP), the compound our body uses for 95% of its energy needs.
In 1998, 144 patients who had been admitted to the hospital after a heart attack, participated in a CoQ10 study. Half of the patients received 120 mg of CoQ10 a day in addition to the usual treatments given to heart attack patients. The other half, the control group, received the usual treatments and a placebo, but no CoQ10.
The results showed that the group taking CoQ10 had less irregular heartbeat, experienced less angina (a type of heart pain), and had much better function in the left ventricle (the most essential chamber of the heart), compared to the placebo group. Total deaths due to sudden heart failure or another heart attack were also reduced in the CoQ10 group.
Q. What if I have already been diagnosed with Congestive Heart failure? Will CoQ10 still help me?
A. CoQ10 has been proven in study after study to help slow down the destruction that occurs in congestive heart failure (CHF), a serious heart disease, and heal the heart muscles damaged by heart attacks. In fact, heart attacks often occur when the body’s CoQ10 levels are low.
In a CHF study, patients received 100 mg of CoQ10 or a placebo twice daily for 12 weeks. Before and after the treatment period, the researchers introduced a catheter into the right ventricle of the patients’ hearts to determine the degree of muscle damage CHF had caused. In the group who took CoQ10, the pumping ability of the heart improved significantly. The placebo group’s hearts did not. The researchers conducting the study recommended that people with CHF add CoQ10 to the other medications they need to take to stay alive and well.
Q. Are some types of CoQ10 better than others?
A. Indeed they are. CoQ10 products are not created equally. The key to this natural medicine is the quality of the manufacturing. Take a CoQ10 supplement that’s been used in research conducted by prestigious universities (it will tell you this right on the label). Researchers want the best CoQ10 for their studies. You want the best CoQ10 for yourself and your loved ones.
The best CoQ10 has to meet the following criteria:
1. Must be easily absorbed during the digestion process so that it can get into the
2. Must reach the mitochondria in the cell.
3. Must be proven effective in studies.
4. Must be safe and free of impurities.
Q. It sounds as if CoQ10 is only for people with moderate or high risk factors. Can others benefit from this supplement?
A. Many people, including those like Fred with low risk factors or no risk of heart disease take CoQ10 every day. CoQ10 supplements may reduce your risk of cancer, prevent gum disease, and help certain nerve cells work more effectively.
Understanding your personal risk factors, making it better lifestyle choices, taking a multivitamin formulated for your heart, an enteric-coated fresh garlic supplement, fish oil supplement with Omega-3 fatty acids, and CoQ10 – the heart’s super-nutrient – can help keep your heart healthy and strong.
Helen Keller, the famous lecturer and author, who was both blind and deaf wrote, “The best and most beautiful things in the world cannot e seen or even touched. They must be felt with the human heart.”
Healthy hearts have the most opportunities to “feel” the best and are the most beautiful thing our world has to offer.
Strontium Bone Maker 60 VC - Strengthen Bones
July 27, 2005 12:06 PM
Helps maintain strong, healthy bones.*
In Vitro and Animal Studies
Strontium is a bone-seeking mineral incorporated by ionic substitution for calcium onto the crystal surface of bone.2 In the test-tube (in vitro), strontium inhibits the activity of osteoclasts, bone cells that break down bone, or “resorb” bone as part of the normal bone remodeling process.3 The effect of strontium, in the form of strontium ranelate (a salt of strontium and ranelic acid), was studied in monkeys over a six-month period. Strontium altered the remodeling of bone in the monkeys, resulting in decreased bone resorption with a concomitant maintenance of bone formation. A trend toward increased volume of osteoid, the organic matrix of bone, was observed, although this was not associated with defects in bone mineralization.4 In another animal study, monkeys fed strontium at high doses for six weeks showed a marked increase in bone strontium content. No harmful effects on bone mineral chemistry or structure occurred.5 At low doses, strontium has been shown to increase the number of bone forming sites in thighbones of adult rats, without adverse effects on the mineral content of bone or mineralization of the organic bone matrix.6 Strontium was shown to reverse bone loss induced by estrogen deficiency in rats.7
Human clinical trials have examined the effect of strontium on bone in postmenopausal women. In the dose-ranging (Phase 2) PREVOS trial, women in early menopause were administered strontium ranelate or a placebo for two years. Strontium ranelate was given at daily doses of 125 mg, 500 mg or 1 gram. (Total weight of compound; strontium plus ranelic acid). Compared to women in the placebo group, who lost bone, women on strontium at the 1 gram dose showed statistically significant increases in bone mineral density (BMD) of the hip, thigh and lumbar spine. Biochemical markers of bone formation, such as serum alkaline phosphatase, increased. No effect on markers of bone resorption was observed, leading to the conclusion that strontium ranelate, at the 1 gram daily dose, increased bone formation without decreasing bone resorption proportionally. It was concluded that 1 gram per day is the minimum effective daily dose of strontium ranelate in these women.8
In another Phase 2 trial (STRATOS trial), 353 postmenopausal women with osteoporosis, who had experienced at least one spinal fracture, took strontium ranelate for two years at daily doses of 500 mg, 1 gram or 2 grams. Women on the 2-gram dose showed a significantly greater increase in lumbar spine BMD than those on placebo. The number of subjects who had new spinal deformities was significantly reduced.9 As in the PREVOS trial, serum levels of alkaline phosphatase, a marker of bone formation, increased, while markers of bone resorption (breakdown) decreased. The overall conclusion is that the minimum effective daily dose of strontium ranelate (whole compound) is 1 gram in early postmenopausal non-osteoporotic women and 2 grams in postmenopausal women with osteoporosis.10
Phase 3 efficacy studies on strontium ranelate have been conducted on 1649 subjects in 12 countries. These studies began with an open-run (non-controlled study period in which subjects took calcium and vitamin D supplements to normalize their blood levels of these nutrients.11 Following this, two parallel groups were administered 2 grams daily of strontium ranelate or placebo for 3-years. The subjects continued to take calcium and vitamin D during the study. In subjects on strontium ranelate, BMD increased in the lumbar vertebrae by 14.4 percent and in the thighbone by 8.3 percent. The number and risk of vertebral fractures decreased.12
Suggested Use: Take two capsules daily. Calcium intake must also be adequate. Do not take this product with calcium supplements.
Strontium ranelate was well-tolerated in the trials discussed above. The incidence of adverse events in subjects on strontium ranelate was statistically equivalent to the placebo groups, and no negative effects on hematology and other biochemical parameters have been observed.
In view of the fact that subjects on the strontium trials also took calcium, and in some cases vitamin D, to maintain normal blood levels of these nutrients, it is important to ensure calcium and vitamin D intakes are adequate when supplementing with strontium. This is underscored by earlier research on animals suggesting that increasing the intake of strontium via diet may demineralize bone when calcium is deficient.13 In rats with chronic kidney failure, strontium has been shown to cause osteomalacia, a condition in which bone is softened due to lack of mineral content. For this reason, people on kidney dialysis should not use strontium supplements.14
1. Shorr E, Carter AC. The usefulness of strontium as an adjuvant to calcium in the remineralization of the skeleton in man. Bull Hosp Joint Dis 1952; 13:59 -66.
2. Dahl SG, Allain P, Marie PJ, et al. Incorporation and distribution of strontium in bone. Bone 2001;28(4):446-53.
3. Baron R, Tsouderos Y. In vitro effects of S12911-2 on osteoclast function and bone marrow macrophage differentiation. Eur J Pharmacol 2002; 450:11-17.
4. Buehler J, Chappuis P, Saffar JL, et al. Strontium ranelate inhibits bone resorption while maintaining bone formation in alveolar bone in monkeys (Macaca fascicularis) Bone 2001;29(2):176-79.
5. Boivin G, Deloffre P, Perrat B, et al. Strontium distribution and interactions with bone mineral in monkey iliac bone after strontium salt (S 12911) administration. J Bone Miner Res. 1996 Sep;11(9):1302-11.
6. Grynpas MD, Hamilton E, Cheung R, et al. Strontium increases vertebral bone volume in rats at a low dose that does not induce detectable mineralization defect. Bone 1996;18(3):253-9.
7. Marie PJ, Hott M, Modrowski D, et al. An uncoupling agent containing strontium prevents bone loss by depressing bone resorption and maintaining bone formation in estrogen-deficient rats. J Bone Miner Res 1993;8(5):607-15.
8. Reginster JY, Deroisy R, Dougados M, et al. Prevention of early postmenopausal bone loss by strontium ranelate: the randomized, two-year, double-masked, dose ranging, placebo-controlled PREVOS trial. Osteoporosis Int 2002; 13:925-31.
9. Meunier PJ, Slosman DO, Delmas PD, et al. Strontium ranelate: dose-dependent effects in established postmenopausal vertebral osteoporosis––a 2-year randomized placebo controlled trial. J Clin Endocrinol Metab 2002;87(5):2060-66.
10. Reginster JY, Meunier PJ. Strontium ranelate phase 2 dose-ranging studies: PREVOS and STRATOS studies. Osteoporosis Int 2003; 14(Suppl 3):S56-S65.
11. Meunier PJ, Reginster JY. Design and methodology of the phase 3 trials for the clinical development of strontium ranelate in the treatment of women with postmenopausal osteoporosis. Osteoporosis Int 2003;14(Suppl 3):S66-76.
12. Meunier PJ, Roux C, Seeman E, et al. The effects of strontium ranelate on the risk of vertebral fracture in women with postmenopausal osteoporosis. N Engl J Med 2004;350(5):459-68. 13. Grynpas MD, Marie PJ. Effects of strontium on bone quality and quantity in rats. Bone 1990;11:313-19.
14. Schrooten, I, Cabrera W, Goodman WG, et al. Strontium causes osteomalacia in chronic renal failure in rats. Kidney Int 1998;54:448-56.
Maintaining Healthy Veins
July 25, 2005 09:36 PM
More than 40 million Americans have varicose veins, a term in Latin meaning “twisted and wollen blood vessel.” Although the condition is rarely disabling, it is disfiguring, causing discomfort and embarrassment to those afflicted.
many cases, genetic predisposition and gender determine who will develop varicose veins. A full 75% of Americans with the condition ar e women. At risk some women who may experience the beginning of this condition during pregnancy as the enlarging womb presses on the veins in the abdomen, increasing the pressure in the veins of the legs.
Age is another factor as the skin becomes less elastic, lessening vein support. Some individuals are genetically edisposed to a malfunction of the one-way valves that may cause a back low of blood to pool in super ficial veins, stretching and swelling them.
some health care professionals believe that our Western diet, high in refined carbohydrates and fat and low in fiber, may cause straining during bowel movement leading to hemorrhoids (anal varicose veins) and increase pressure on the leg veins. Our Western diet also eads to obesity and cardiovascular conditions such as plaque deposits in the arteries, abnormal clotting and platelet aggregation, cardiac dysfunction or failure, all leading to a weakened venous system that could increase the chance of developing varicose veins and edema (swelling in the legs). Those who ar e predisposed to varicose veins and who stand for long periods of time, especially on hard floors, may develop them more quickly.
If you are at risk of developing this condition as you age, emphasizing a diet high in fiber, legumes and grains, fresh fruits and vegetables will improve your chances of maintaining good vein health. Other nutritional supplements that may be beneficial are horse chestnut seeds, Centella Asiatica, Milk Thistle, Butcher’s Broom and bioflavonoids.
Horse chestnut seeds have a long historical use in the treatment of varicose veins and hemorrhoids. One active ingredient that has been researched is a saponin mixture called Aescin. In a recent study, Aescin was as effective as compression stockings in reducing leg swelling in patients with chronic venous insufficiency.
Centella Asiatica is a common edible herb also known as Gotu Kola in India. When grown in Madagascar, it has a higher content of a compound called triterpenic fraction (TTFCA) than the same herb has when grown in other parts of the world. This compound has been used for many years in the treatment of venous hypertension. In a study conducted in 1989, 120mg dosage was safely used in patients with poor venous blood flow and it improved the condition after one or two months.
Often, inflammation is a component of varicose veins. Milk Thistle, another herb commonly used for the treatment of liver disorders, was also found to reduce inflammation and edema in a recent Spanish study.
A bushy ever green perennial found throughout much of the Western world is Butcher’s Broom. Its saponin glycosides ar e anti-inflammatory and helped contract blood vessels, especially veins thus making it an important component of any natural for mulation used to improve venous conditions.
Certain bioflavonoids, such as quer cetin and rutin, have also been shown to be useful in the natural tr eatment of varicose veins as a strengthener of capillary and vein walls.
There are other nutritional supplements including vitamins and minerals that may help maintain vein health as we age. They are listed in my new book “A Doctor’s Guide to Natural Medicine.” To improve vein health and to decrease your chance of developing varicose veins: do not stand for long periods of time especially on hard sur faces such as concrete. If you can’t avoid this, make sure your shoes are well cushioned. If you are sitting for long periods of time either working or traveling, take walking breaks. Stop crossing your legs and exercise regularly to incorporates rhythmical contraction of the leg muscles. Rest with your legs elevated when taking a break. W earing good support hose and avoiding tight knee-highs will promote good blood flow.
These things can be very important if you ar e genetically pr edisposed to varicose veins. Starting nutrients early may help diminish or delay venous problems.
Micromedex, Inc. Volume 96, 1974-1998. Diehmetal. Microcirculation Laboratory, Cardiovascular Clinic, Chieti, Italy.
Efficacy of Centellase in the Treatment of Venous Hypertension Evaluated by a Combined Micro circulatory Model. G. Belcaroetal. Current Therapeutic Research, Vol. 46, No. 6, Dec. 1989.
Effect of Silymarin on Different Acute Inflammation Models and on Leukocyte Migration. R. de la Puertaetal, J. Pharm. Parmacol. 1996, 48: 968-970 Merck Sciential Review, no. 10, 1995-04-30, pp. 2
The Management of PMS and Ginkgo
June 25, 2005 12:35 PM
The Management of PMS and Ginkgo
Symptoms of PMS usually include water retention, breast tenderness and vascular congestion. One hundred sixty-five women between the ages of 18 and 45 who suffered from significant PMS were tested with ginkgo, which was given from the 16th day of the first cycle to the 5th day of the next. Test studies confirmed that ginkgo was effective against various symptoms of PMS, particularly b reast changes. In addition, mental and emotional symptoms associated with PMS also decreased.15 Because Ginkgo is so safe to use, it may be very beneficial for women who have used drug therapy for PMS that had undesirable side effects.
Ginkgo: An Update
Ginkgo is currently being studied as a safer substitute for antirejection drugs which are routinely given to recipients of transplanted organs. Ginkgolide, the active component of ginkgo, somehow inhibits a chemical found in the body called PAF (platelet activating factor) which plays a role in organ rejection. It may also prove beneficial for congestive heart failure, angina, shock, multiple sclerosis and burns.
The Latest Breakthroughs in Garlic Research on Cancer and Cardiovascular Disease
June 09, 2005 05:22 PM
The Latest Breakthroughs in Garlic Research
on Cancer and Cardiovascular Disease
Presented at the 2005 World Garlic Symposium
Many of the world’s top-level scientists gathered in Washington D.C. this week for the 2005 Garlic Symposium, entitled, “Significance of Garlic and its Constituents in Cancer and Cardiovascular Disease.” The conference provided current scientific information about the effect of garlic and its constituents on health and performance. The symposium was held at the Georgetown University Conference Center on April 9-11, 2005.
“For the first time in seven years authorities in various fields of garlic research from all over the world to provide the latest updates, specifically regarding aged garlic extract and its actions in diseased states including heart disease and cancer,” commented Dr. Matthew Budoff, M.D. cardiovascular researcher at UCLA. “Garlic has been used medicinally for thousands of years in virtually all ancient cultures. Now, new metabolic roles for garlic are being proposed and there are many promising lines of research.”
Presentation highlights included:
Effect of aged garlic extract (AGE) has been tested in the placebo-controlled double blind randomized clinical study that determined that the atherosclerotic plaque burden detected by electron beam tomography (EBT) changed significantly with the use of aged garlic extract, Patients in Dr. Budoff’s study were able to significantly lower their total cholesterol, blood pressure, homocysteine and LDL cholesterol oxidation levels with aged garlic extract supplementation.
“Garlic is turning out to be a major player in cancer and heart disease prevention and control, especially in combination with drug treatments,” said Richard Rivlin, M.D. of Strang Cancer Prevention Center at Cornell. “It’s also showing us that we can start early. It’s madness to treat cancer and heart disease in their advanced stages. We need to start early and aged garlic extract is an excellent way to do that.”
Almost 400 scientific studies have been completed on aged garlic extract, done in major universities worldwide. These studies have focused on a variety of heart disease risk factors such as cholesterol, high blood pressure, homocysteine levels, inhibiting LDL oxidation, anti-platelet aggregation and adhesion, stimulating blood circulation; in addition to other studies on immune stimulation, cognitive effects, liver function and anti-tumor effects. .
PRECLINICAL PERSPECTIVE ON GARLIC AND CANCER. John A. Milner, National Cancer Institute, Rockville, MD 20892
Mounting evidence points to the anticancer properties of fresh garlic extracts, aged garlic, garlic oil, and a number of specific organosulfur compounds from garlic. These prevention characteristics arise through both a dose and temporal related change in several cellular events including those involving drug metabolism, immunocompetence, cell cycle regulation, apoptosis and angiogenesis. A block in carcinogen activation through modulation of cytochrome P450-dependent monooxygenases and/or acceleration of carcinogen detoxification via induction of phase II enzymes likely account for some of this protection. The block in preneoplastic lesions and/or tumors in several sites suggests a generalizable mechanism. The efficacy of water- and lipid-soluble allyl sulfur compounds against chemical carcinogenesis appears comparable, although more studies are needed. A shift in sulfhydryl groups, redox status or enzyme catalysis may account for some of the phenotypic changes. They may also account for the observed hyperphosphorylation of specific cell cycle related proteins and histone hyperacetylation; both of which have been correlated with suppressed tumor cell proliferation. Several forms of allyl sulfur compounds are effective in blocking cell division and inducing apoptosis, but notable differences in the efficacy among these various compounds and across tumor types are evident. While the expression of many genes and proteins can be influenced by allyl sulfides; the challenge is to determine which is responsible for a phenotypic change. Additional studies are needed with more modest exposures and over prolonged periods and that utilize transgenic and knockout models to assist in the identification of molecular targets. Finally, additional research is needed to identify sensitive “effect” and “susceptibility” biomarkers that can ultimately be used to identify responders from non-responders.
INHIBITION OF CORONARY ARTERIAL PLAQUE ACCUMULATION BY GARLIC. Matthew Budoff, Harbor-UCLA Medical Center, UCLA School of Medicine, California, USA
Effect of Aged garlic extract (AGE) has been tested in the placebo-controlled double blind randomized clinical study to determine whether the atherosclerotic plaque burden detected by electron beam tomography (EBT) will change at a different rate under the influence of AGE or placebo. EBT can non-invasively quantitate the amount of coronary calcification and track atherosclerotic plaque over time. Nineteen of 23 patients completed the study protocol. The patients were well matched for age, gender, statin use and cardiac risk factors. Patients underwent EBT and blood testing at baseline, and then again after 12 months of randomization. The average change in the calcium score (Volumetric method) ± SD for the AGE group (n = 9) was 7.5 ± 9.4% over the one year. The placebo group (n = 10) demonstrated 22.2 ± 18.5% annual progression, significantly greater than the treated cohort (p = 0.01). While there were no significant changes in cholesterol parameters, or C Reactive protein between the groups, high density lipoproteins and plasma homocysteine in the AGE group demonstrated a trend toward improvement compared to the placebo patients. Thus, although this is a small-scale trial, it demonstrates the potential of AGE to inhibit the rate of atherosclerosis (progression of coronary calcium), as compared to placebo over one year. Larger studies need to be performed to assess this potential anti-atherosclerotic therapy and the impact on coronary events.
INFLUENCE OF GARLIC ON ENDOTHELIAL DYSFUNCTION IN HYPERHOMOCYSTEINEMIA. N. Weiss, N. Ide, T. Abahji, L. Nill, C. Keller, U. Hoffmann. Klinikum der Universität München, D-80336 Munich, Germany
Endothelial dysfunction (ED) due to decreased bioavailable nitric oxide (NO) by increased vascular oxidant stress plays a critical role in the vascular pathobiology of hyperhomocysteinemia (hhcy). Aged Garlic Extract (AGE) minimizes intracellular oxidant stress and stimulates NO generation in endothelial cells. We performed a placebo-controlled, blinded, cross-over study to examine whether AGE prevents macro- and microvascular ED during acute hhcy induced by an oral methionine challenge in healthy subjects. Acute hhcy leads to a significant decrease in flow-mediated vasodilation of the brachial artery as determined by vascular ultrasound, indicative of macrovascular ED, as well as a decreased number of recruited nailfold capillaries during postischemic reactive hyperemia as determined by videomicroscopy, and to a decreased ratio of acetylcholine (endothelium-dependent) vs. sodium nitroprusside (endothelium-independent) iontophoresis induced skin perfusion as measured by laser doppler flowmetry, indicative of microvascular ED. Preliminary results show that pretreatment with AGE for six weeks diminishes the adverse effects of acute hhcy on endothelium-dependent brachial artery vasodilation and on acetylcholine-induced stimulation of skin perfusion. Whether or not this is accompanied by changes in biochemical parameters of ED is still under investigation. It is concluded that AGE may at least partly prevent a decrease in bioavailable NO during acute hhcy.
David Heber, MD, PhD, FACP, FACN
Professor, UCLA Department of Medicine - Division of Clinical Nutrition, at the David Geffen School of Medicine, UCLA, and UCLA School of Public Health; Director, UCLA Center for Human Nutrition; Director, NIH Center for Dietary Supplement Research in Botanicals (CDSRB); Director, NCI-funded Clinical Nutrition Research Unit; Vice Chair, UCLA Collaborative Centers for Integrative Medicine; Member, UCLA's Jonsson Comprehensive Cancer Center
Matthew Budoff, MD, FACC
Matthew Budoff, MD, FACC, is an associate professor of medicine at the UCLA School of Medicine and program director for the Division of Cardiology, as well as director of the Electron Beam CT Laboratory at Harbor-UCLA Medical Center in Torrance, Calif. He completed his undergraduate work at University of California, Riverside, and earned his medical degree at George Washington University in Washington D.C. Dr. Budoff’s efforts to identify and modify risk factors for cardiovascular disease using electron beam CT have been extensively published. His latest research focuses on the progression of arteriosclerosis.
Heart Science - A Five-Tiered Approach to Heart Health ...
June 02, 2005 12:07 PM
Your heart is crucial to every function of your body. It is the sole organ which pumps oxygen-rich blood through the entire circulatory system, feeding your cells and making life possible. Only recently are Americans realizing the importance of a proper low-fat diet, regular exercise, giving up cigarette smoking, and cutting down alcohol consumption to maintaining a healthy heart. Unfortunately, there has been a huge gap in the number of nutritional supplements which provide nutrients and herbs to support normal heart function. That’s where Source Naturals HEART SCIENCE comes in. Two years in the making, and backed by numerous scientific studies, the nutrients in HEART SCIENCE are some of the most soundly researched of all. Combining high potencies of these super-nutrients, HEART SCIENCE is the most comprehensive, cutting edge nutritional approach to proper heart care available.
Source Naturals HEART SCIENCE— The Five Tiered Approach to Heart Health
Your heart never rests. Even while you sleep, your heart must keep working, relying on the constant generation of energy by the body for its very survival. If this vital organ stops beating for even a short amount of time, all bodily functions cease and life ends. Source Naturals HEART SCIENCE helps support heart function on the chemical, cellular, structural, and energetic levels. This broad spectrum formula includes ingredients specifically geared for
Energy Generators for An Energetic Organ
Every day, the human heart beats about 104,000 times, pumping over 8,000 liters of blood through the body! Because it requires so much energy to perform efficiently, the experts at Source Naturals included specialty nutrients in HEART SCIENCE such as Coenzyme Q10 and L-Carnitine — integral factors in the body’s energy production cycles — to enhance the body’s energy supply.
There are three main interconnected energy generating cycles in our cells — the Glycolytic (sugar-burning) cycle, the Krebs’ (citric acid) cycle, and the Electron Transport Chain. Together they supply about 90 to 95% of our body’s entire energy supply, using fats, sugars, and amino acids as fuel. Coenzyme Q10 is one of the non-vitamin nutrients needed to maximally convert food into ATP (the energy producing molecule). It is the vital connecting link for three of the four main enzyme complexes in the Electron Transport Chain, the next step in energy generation after the Krebs’ cycle. Using the raw materials generated by the Krebs’ cycle, the Electron Transport Chain produces most of the body’s total energy! The heart is one of the bodily organs which contains the highest levels of CoQ10, precisely because it needs so much energy to function efficiently.
CoQ10 is one of the most promising nutrients for the heart under investigation today. It has been postulated that as a result of its participation in energy production, CoQ10 improves heart muscle metabolism and the electrical functioning of the heart by enhancing its pumping capacity.8 Many factors such as a high fat diet, lack of exercise, and cigarette smoking can lead to suboptimal functioning of the heart, and therefore failure of the heart to maintain adequate circulation of blood. Interestingly, people whose lifestyles reflect the above factors also tend to have depleted levels of CoQ10 in the heart muscle.10
Researchers suggest taking between 10-100 mg per day of CoQ10;18,29 HEART SCIENCE provides an impressive 60 mg of CoQ10 per 6 tablets. Similar to CoQ10, L-Carnitine is important for energy production in heart cells. It is a natural amino acid-like substance which plays a key role in transporting fatty acids, the heart’s main source of energy, to the mitochondria, the “power plants” of each cell, where they are utilized for the production of ATP. Heart and skeletal muscles are particularly vulnerable to L-Carnitine deficiency. Studies have shown that supplementation with LCarnitine improves exercise tolerance in individuals with suboptimal heart and circulatory function, and seems to lower blood lipid status and increase HDL (good) cholesterol.16, 22 Each daily dose of HEART SCIENCE contains 500 mg of this extremely important compound.
Like CoQ10 and L-Carnitine, B Vitamins help improve the ability of the heart muscle to function optimally. Each B Vitamin, after being converted to its active coenzyme form, acts as a catalytic “spark plug” for the body’s production of energy. Vitamin B-1, for example, is converted to Cocarboxylase, which serves as a critical link between the Glycolytic and Krebs’ Cycles, and also participates in the conversion of amino acids into energy. A deficiency of B coenzymes within contracting muscle cells can lead to a weakened pumping of the heart.21
HEART SCIENCE is formulated with high quantities of the most absorbable forms of B Vitamins providing maximum nutrition for the high energy demands of heart cells.
B Vitamins also play a crucial role in the conversion of homocysteine, a group of potentially harmful amino acids produced by the body, to methionine, another more beneficial amino acid. While it is normal for the body to produce some homocysteine, even a small elevation in homocysteine levels can have negative implications. It is well documented that individuals who are genetically predisposed to having elevated homocysteine levels (homocysteinemics) tend to have excessive plaque accumulation in the arteries and premature damage to endothelial cells (cells lining the blood vessels and heart).26 Researchers have found that even those without this genetic abnormality, whose homocysteine levels are much lower than those of homocysteinemics, still have an increased risk for premature endothelial damage and the development of plaque in the arteries.24, 26 One study conducted among normal men and women found that those with the highest levels of homocysteine were twice as likely to have clogged arteries as were those with the lowest levels.24 Furthermore, it was found that the lower the research subjects’ blood levels of folate and B-6, the higher their homocysteine levels.24 Another study found that Folic Acid administered to normal men and women who were not even deficient in folate caused a significant reduction in plasma concentrations of homocysteine!3 In order to regulate homocysteine levels, it is critical to provide the body with sufficient amounts of B-6, B-12, and Folate, whether through the diet or through supplementation. HEART SCIENCE includes high levels of these three nutrients, providing B-6 in the regular and coenzyme form for maximum utilization.
The Dangers of Oxidized LDL Cholesterol
While many people have heard that high cholesterol levels may negatively affect normal heart function, few people understand exactly what cholesterol is, or how it can become harmful. Cholesterol is a white, waxy substance produced in the liver by all animals, and used for a variety of necessary activities in the body. Your liver also manufactures two main kinds of carrier molecules which transport cholesterol throughout the system: Low Density Lipoprotein (LDL) and High Density Lipoprotein (HDL). Cholesterol is either carried out by LDL from the liver to all tissues in the body where it is deposited, or carried back by HDLs which remove cholesterol deposits from the arteries and carry them to the liver for disposal. Because of this, LDL cholesterol is considered damaging, while HDL is considered protective. Problems occur when there is too much LDL cholesterol in the body and not enough HDL.
When the body becomes overloaded with fat, an over-abundance of LDL particles are manufactured to process it, and they in turn become elevated in the body to a degree that the liver cannot handle. Rich in fatty acids and cholesterol, these particles are highly susceptible to free radical attack (oxidation). Once oxidized, LDL particles are no longer recognized by the body, which attacks them with immune cells. Immune cells which are bloated by oxidized lipids (called foam cells) are a key factor in the development of “fatty streaks” — the first sign of excess arterial fat accumulation. The bloated immune cells accumulate in artery lesions and create plaque in blood vessels, leading to obstruction and constriction of the vessels. Plus, these lodged foam cells continue to secrete free radicals into the bloodstream, making the problem worse.
The development of lesions in the arteries is not an uncommon problem. Arterial (and all blood vessel) walls are composed of a chemical matrix which holds the endothelial cells in place. That endothelial layer is the first and most important line of defense in preventing large molecules, such as cholesterol and fat, from entering the vessel wall. This matrix is composed of proteins, collagen, elastin, and glycosaminoglycans (amino sugars). Arterial lesions can be caused by suboptimal collagen and elastin synthesis due to three factors: 1. Vitamin C deficiency (since Vitamin C is a key building block for collagen and elastin); 2. excessive consumption of rancid fats, or heavy usage of alcohol or cigarettes; and 3. free radical damage. Once these lesions are created, the body attempts to repair them by depositing LDL cholesterol — similar to the way one would patch a tire. If that cholesterol is not oxidized, i.e. chemically changed to a harmful, unstable molecule, then this process does not create a problem. But when arterial lesions are “patched” with foam cells, arterial walls suffer page 3 page 4 even more damage, because those foam cells release free radicals which can further damage cell membranes.
Unfortunately, most people have a lot of oxidized cholesterol floating through the bloodstream. The typical American diet, with its low antioxidant intake and overconsumption of fried and overcooked foods, contributes to the overall levels of harmful oxidized cholesterol. In fact, the average American intake of antioxidants is low even by USRDA standards, making Americans particularly prone to having high levels of oxidized cholesterol.
Fortunately, there are concrete steps you can take to prevent the oxidation of cholesterol, and its subsequent ill effects on health. In addition to cutting out high-cholesterol and fatty foods, supplementation can protect existing cholesterol and all tissue cells — from oxidation. Antioxidants, substances which scavenge and neutralize free radicals, protect the cardiovascular system by halting the oxidation of cholesterol, and helping to prevent plaque accumulation in the arteries and the continual secretion of free radicals by foam cells. Supplementing the diet with high amounts of Vitamin C, a key antioxidant, also encourages a more healthy “patching” of existing lesions by using collagen (made from Vitamin C) instead of cholesterol. HEART SCIENCE contains generous amounts of the following antioxidants for their protective benefits:
The Regulating Trio
Three nutrients — Magnesium, Potassium, and Taurine — work closely together in the body to help maintain the normal electrical rhythm of the heart, promote proper fluid balance, and prevent excessive Calcium levels from building up in the heart and artery linings.
Artery Lining Protectors
Your arteries form an integral part of your cardiovascular system, carrying blood away from the heart to nourish other parts of the body. In a healthy heart, blood surges through the arteries with every beat of the heart. The arteries expand with each pulse to accommodate the flow of blood. When arteries become hardened and narrowed by the build-up of plaque, they can’t expand and are not able to transport blood efficiently throughout the body. This inability to open up increases blood pressure, putting a strain on the heart as well as the arteries. HEART SCIENCE includes ingredients specifically geared to protect against plaque formation within arteries and maintain the flexibility of these vital blood vessels. N-Acetyl Glucosamine (NAG) is a key amino sugar which forms the building blocks of mucopolysaccharides. Mucopolysaccharides, which are long chain sugars, are an integral component of connective tissue. They combine to form gel-like matrixes which are present throughout tissues in the body, helping to maintain the elasticity of blood vessels which must continually adapt to the changing pressures of blood flow. Each daily dose of HEART SCIENCE provides 500 mg — a substantial amount — of this vital tissue building block. There is evidence indicating that Silicon, a natural mineral, may protect against plaque formation in the arteries. Silicon is found mainly in connective tissues, where it helps bind the body’s chemical matrix. Bound Silicon is found in high amounts in arterial walls. Researchers have found that there is a steady decline in the Silicon content of the aorta and other arteries as we age. This may be due to the low fiber content of the typical American diet, since fiber is a key dietary source of Silicon.23 HEART SCIENCE includes 400 mg of Horsetail herb extract, a natural source of Silicon. Hawthorn Berry is without question the herb most widely used to encourage normal heart function. The beneficial actions of Hawthorn Berry on cardiac function have been repeatedly demonstrated in experimental studies. Supplementation with Hawthorn Berry has been shown to improve both the blood supply to the heart by dilating coronary vessels, and the metabolic processes in the heart, resulting in normal, strong contractions of the heart muscle.34 Also, Hawthorn may inhibit the angiotensen converting enzyme, which is responsible for converting angiotensen I to angiotensen II, a powerful constrictor of blood vessels.34 Bromelain, a natural enzyme derived from pineapples, has become well-known for its neuromuscular relaxing properties. Researchers have reported favorable results when using Bromelain for soothing vascular linings. Initial research also indicates that Bromelain may break down fibrin, the glue which holds platelets together to form blood clots.6
Capillaries are the smallest, yet some of the most important, blood vessels. If you think of your cardiovascular system as a series of roads which transport blood and oxygen, then your arteries are akin to interstate highways, your arterioles are the main city boulevards, and your capillaries are local residential streets. Capillaries are so small, in fact, that single red blood cells actually have to fold up to fit through them. Because of their tiny size and the intricate nature of their network throughout the body, capillaries are responsible for actually nourishing each individual tissue cell! Along the length of the capillaries are small openings called slit pores through which oxygen, glucose, and nutrients leave the capillaries and enter the surrounding interstitial fluid. From there, they cross cell membranes and nourish the cells. Similarly, the waste products of cells enter the fluid and cross over into the capillaries, where they are then transported to the liver and kidneys for disposal. If the capillary slit pores are torn or have lesions, then blood proteins and Sodium will leak out and cause the interstitial fluid to take on a more gel-like nature. This makes the transfer of oxygen and nutrients to the cells more difficult, as well as the disposal of cell waste products, turning the fluid into a stagnant swamp instead of a flowing river. In addition to its powerful antioxidant actions, Proanthodyn also helps protect collagen and elastin, the main constituents of tissue in the capillaries, and throughout the body. It is absolutely essential for capillary walls — which are only one cell thick — to be strong and stable, so that they do not allow blood proteins to leak into the interstitial fluid. Once the interstitial fluid takes on a gel-like consistency, the surrounding cells literally become starved from lack of nutrition. The exciting news is that the proanthocyanidins contained in Proanthodyn are among the few substances yet discovered which can help strengthen capillary walls, ensuring the liquid nature of the interstitial fluid.2 Plus, proanthocyanidins help keep capillary and artery walls flexible, allowing for proper blood flow to the heart.
The 1990’s mark a decade of increased awareness among Americans of important health issues. Much of the discussion has revolved around protecting that precious center of life we call the heart. Simple lifestyle change is one of the most effective ways to maintain and protect the functioning of the cardiovascular system. In order to take a holistic approach to heart care, make sure you include plenty of fresh fruits and vegetables (organic, if possible) in your diet, and cut down on fatty and cholesterol-forming foods. Reduce your salt and alcohol intake to a minimum. Try to get regular, sustained aerobic exercise for at least 30 minutes three times a week. Don’t smoke – or if you do smoke, try to eat even more fresh fruits and antioxidant-rich vegetables to counter the amount of free radicals being produced in your body. Lastly, consider adding Source Naturals HEART SCIENCE to your health regimen. HEART SCIENCE, the most comprehensive formula of its kind, provides targeted protection to the entire cardiovascular system. By approaching the promotion of normal heart function on five different levels — through the inclusion of ingredients which supply energy, decrease harmful homocysteine levels, fight cholesterol build-up, help regulate electrical rhythm, and protect artery and capillary linings — HEART SCIENCE is the perfect addition to a holistic approach to heart care.
Source Naturals HEART SCIENCE™