Search Term: " pilo "
Higher omega-3s status linked to less depression in population withheart failure
September 20, 2018 05:11 PM
A recent American College of Cardiology study of 108 chronic heart failure patients noted that patients with higher omega-3 index levels as a result of oral supplementation appear to suffer less from depression than the control group. Roughly 20 percent of chronic heart failure patients become clinically depressed. The promising results suggest that increased omega-3 index levels may result in better social functioning and reduced cognitive symptoms of depression as measured by the widely-used Hamilton Depression Scale. More research is needed, however, to better understand the impact of omega-3 indexes on depression.
"A recent pilot study has linked a higher Omega 3 Index with lessened symptoms of depression in a cohort of subjects suffering from chronic heart failure."
Read more: https://www.nutraingredients-usa.com/Article/2018/08/22/Higher-omega-3s-status-linked-to-less-depression-in-population-with-heart-failure
Alzheimer's Disease: What You Can Do to Prevent Holiday Memories from Vanishing
November 26, 2017 03:59 PM
Alzheimer's, like most diseases comes with its own set of problems, the memory loss being number one. Much like other diseases it is important to find those symptoms early. One easy way to help with that is mind exercises. These help with neuro plasticity and will allow your brain to function in top condition for years to come. Much like exercising works for the heart, muscles, and flexibility these exercises keep the brain healthy. Try them out!
"Prevention and early detection of first signs of cognitive impairment and treating its cause is key to maintaining a healthy brain throughout life"
Read more: http://www.latimes.com/socal/daily-pilot/opinion/tn-dpt-me-commentary-shankle-20171122-story.html
Research pilot explores industrial hemp
September 07, 2017 12:14 PM
Although the Washington state legislature has allowed hemp to once again be grown in the state, there are still some questions and uncertainties about growing the product. For now, those growing hemp are doing it for research purposes to monitor what the future growers will need it to do in order to create an industrial hemp harvest. Despite the four different types of licenses being granted, there is still some caution because of the plants close relationship it to marijuana. Hopefully some restrictions will change and beneficial aspects of the hemp can be produced, such as CBD oil.
"Hector Castro, Olympia-based communications director for the WSDA, says although the program is new, it’s generated a lot of interest from farmers and others who see potential in harvesting hemp."
Read more: https://www.spokanejournal.com/local-news/research-pilot-explores-industrial-hemp/
Is CBD the Next Big Thing for Acne?
July 19, 2017 07:14 PM
CBD may be the next big thing for acne. Synthetic cannabis has yielded some surprising results and it is a great way to treat acne. The phase 1 clinical trial has just been finished by a dermatological company. The goal of this drug is that one day it will be the answer for people struggling with acne. The clinical trials began last year in Australia. There is going to be a pilot program for acne patients later this quarter.
Read more: Is CBD the Next Big Thing for Acne?
Curcumin Study Shows Improved Bone Density
June 01, 2017 07:14 PM
A pilot study that took place in Milan, Italy has made some remarkable findings. In this study a group of individuals were split into groups. One had the additional supplement of Curcumin added to their daily regime. After a period of time they were tested and it was found that the group that consumed the Curcumin had increased bone density. The test sites were the jaw and fingers. This is great news for people who suffer with bone density issues and more studies are underway.
Read more: Curcumin Study Shows Improved Bone Density
Lutein and brain health: Enriched formula leads to selective increases in multiple brain regions
January 31, 2017 12:59 PM
Lutein has been tested in more primates than humans and its link to brain and ocular health is fairly significant. Scientists have noted an increased need in lutein among babies- in utero and also after they are born. Lutein can be added to and consumed in infant formula. Lutein is a strong antioxidant and can be very useful for developing babies.
"All of the brain regions examined – the prefrontal cortex, the occipital cortex, the superior temporal cortex, the striatum, the cerebellum, and the hippocampus – all displayed selective increases in lutein deposition, with the highest amounts in the occipital cortex."
Does a vegan diet affect your ability to heal?
January 16, 2017 02:59 PM
For all you vegans out there what if I told you being a vegan may give you the ability to heal faster? Sounds crazy I know but recently a once vegan man survived a brutal plane crash. There is no proof of this but some researches and scientist believe this may be true.
"The pilots, who thought that they had blown a tire, were unable to stop the plane on the remaining runway they had left."
How does a high-protein diet aid weight loss? Study sheds light
November 24, 2016 10:59 AM
Are you trying to lose weight? It seems like there is a ton of tips out there and a lot of it is going the route of contradicting each other. No matter where you look, there's something that's supposed to help you lose weight compared to something else (nevermind what helps weight gain!). "How does a high-protein diet aid weight loss? Study sheds light" gives proof that a high-protein diet is actually better than all those other tips...
"Lead author Mariana Norton will present the findings at this week's Society for Endocrinology annual meeting in the U.K."
Does Bilberry Have Healing Properties?
March 28, 2014 07:09 PM
What is a bilberry
The Bilberry fruit grows in Europe and North America. In Europe, it is known for its mending properties for a long time. Furthermore, Vaccinium myrtillus, is the Latin name for bilberry berries.
Benefits of bilberry
Bilberry discovered generally in dull cleaned fruits. It is utilized to treat loose bowels, varicose veins, and mucous film aggravation. The herb is valuable in the medicine of solidifying of the conduits (atherosclerosis) and in eye health.
This herb might additionally help night vision. Throughout World War II, British pilots consumed bilberry stick before going out on night flights. They asserted it enhanced their vision. It is accepted that the bilberry herb helps the eyes to change in accordance with progressions in light rapidly. This is one of the best benefits of bilberry and could be exceptionally valuable for one’s eyes as stated by numerous studies.
In Europe, it is utilized to treat venous deficiency a condition that causes swelling and varicose veins. It further assuages torment and tingling, and it likewise. Helps battle skin ulcers on the legs. Reynaud's infection may profit from the bilberry. Reynauds reasons torment and deadness in the external limits (fingers, toes and nose) when chilly.
Bilberry enhances dissemination and makes course dividers. The herb may lessen aggravation, simplicity gastro-intestinal issues, and gum issues that have been joined to coronary illness. Loose bowels and mouth injuries can profit from Bilberry too. Bilberry has solid clean properties, alleviates peptic ulcers, diabetes, fibrocystic maladies, and tormenting feminine cycle.
In view of Bilberry's makes a great free radical forager, which helps battle the cell harm that prompts untimely maturing and malady. The most noted profit that we quickly talked about is its capability to treat an extent of issues identifying with one’s eye health. Case in point, the herb ensures collagen structures in the veins of the eyes, in this way, pushing solid vessels that convey numerous crucial supplements, for example, and oxygen-rich blood to your eye muscles.
Can Bilberry Extract Improve Eye Site?
November 05, 2013 10:11 PM
Can Bilberry Extract Improve Eye Site?
Do you problems with your eyes? Maybe your night vision is poor and you have been wondering where you can get natural drugs to improve or rectify this condition. Worry no more as this article presents you with the ultimate solution. Research has shown that Bilberry extract works well to improve eye site.
What is Bilberry
Bilberry, an herbal supplement, also known as Vaccinium myrtillus or myrtille, is a shrub found in European countries similar to the huckleberry or the blueberry. This extract has a long history since it was used as early as 16 century. However, it was not until Second World War II when its use was modernized. The first people to use it were the US and British pilots who ate it as part of their diet. Surprisingly, they realized a tremendous improvement in their night vision when they were at work during the night.
This extract is known to be rich in flavorings, also known as polyphenols, a substance that improves eye’s circulatory system and improves the overall eye health. Thus, when supplemented with diet, night vision will be improved.
Uses of Bilberry
In addition, this extract has been known to treat a variety of retinopathy conditions. A condition that damages nerves and blood vessels of the retina. In some countries like France, this extract has been used since 1945 to treat diabetic retinopathy, a condition that causes blindness in diabetics.
Various studies have shown that this extract is a useful medical herb. One of them stated that Bilberry extract could be used with vitamin E to prevent the progression of cataracts. This studies was conducted among 50 patients suffering from cataracts, and only of them did not recover.
Benefits of Bilberry
In conclusion, this extract has many benefits; support for glaucoma, reduce eye fatigue, and improve poor night vision. Therefore, wait no more, get yourself this extract and your eye problems will be something of the past.
October 27, 2012 11:25 AM
The use of bilberry extracts dates back to 1000 years ago where many people attest success when they are applied to the eye. Bilberry is considered a powerful anti-inflammatory and antioxidant used to treat the eye problems such as cataracts, muscular degeneration, and neuropathy.
As one ages, there is tendency that the eye blood vessels thickens due to consumptions of fats. Bilberry application helps to reduce the inflammation and strengthen then artery walls of the vessels within the eye area, and therefore improves the vision. Clinical studies suggest that proper blood circulation within the eye also reduces the chances of blindness in the early ages.
Moreover, thick arteries contribute to the swelling of the eyes. In extreme circumstances, swollen eyes hamper vision and make it difficult for an individual to walk without help of a friend. If this condition is untreated, atherosclerosis develops thereby worsening the eye health. To avert this, bilberry is eaten in extract form or as a fruit. It will eventually reduce the thickness of the arteries within the body circulatory system. During the Second World War, the fruit extract was eaten the soldiers who fought throughout the nights. pilots also ate them as it was regarded to enhance the night vision. It was until recently that publicity of the extract was recognized worldwide and it has been commercialized as an eye supplement.
Bilberry also improves the vision at night. Many studies have indicated that consumption of bilberry jam helps to increase vision during the night. Bilberry extract contains anthocyanins which is a useful ingredient for the production of rhodopsin. Rhodopsin is known to enhance the night vision by aiding the eye to adjust to insufficient light during night and therefore enhances vision.
What Makes A Good Vision Formula?
April 09, 2012 07:27 AM
Although there are many types of vision formula products in the market, a good number of them are not what you really need for your healthy eyes. This is because although they may contain various good nutrients, they might also lack some components that are vital to your general health. Many people forget that the eye is in fact only one organ of the body, and it cannot function on it's own. Problems in someone's vision are often an indication of the general unhealthy state of the body. A good vision formula, therefore, has to be blended in such a way that it contains all the required nutrients for the eye. while being free of any ingredients that can be harmful to the eye or any part of the body.
A Good Eye Formula Contains:
For any vision formula, vitamin A is a must-have. This is arguably the most important nutrient for the eyes. In fact, there is hardly such a time that the eyes have enough vitamin A from the foods we eat.Carrots have a reputation for being good for the eyes simply because they are rich in vitamin A. Along with vitamins E and C, it acts as an antioxidant which help to promote a clear vision.
Bilberry is another very important ingredient. It helps to enhance better night-vision, and helps people to see more clearly when there is very little light.It does this by enabling the pupils of the eyes to open wider thus allowing more light to enter the eye.Bilberry is so effective that during the second world war, it is said that British pilots used to eat them every time they fly.The black carrent is another nutrient that also helps in improving night vision.
Lutein makes another vital nutrient that a good vision formula should contain.It is one of the best natural antioxidants known to man. Among it's roles is protecting the eye from dangerous blue light, which can badly damage a person's vision. It also reduces the possibility of macular degeneration -a condition which is associated with aging. Lutein is not just important to the eyes alone, but also to the skin.The fact that it helps to filter out the blue light rays, means that it is needed by the skin too, because the skin also needs protection from these dangerous rays.It is known also to redeem the free radicals, which are very important to the eyes and need protection from damage.
There are other very important ingredients of a good vision formula, including Blueberry, Taurine and copper, which are important in facilitating a clear vision as well as enhancing the general good health of the eye.It is important that you take note of the fact that not all eye problems can be remedied by a vision formula. While a vision formula can be of great help in enhancing the way you see, some problems may require the attention of a specialist. It is therefore advised that you seek help from such specialists who can understand your problem better and help you solve them accordingly.
September 05, 2008 09:02 AM
Bilberry has been used most commonly for centuries as a food, with the English traditionally eating bilberries with a rich cream. Large amounts of bilberries were imported annually from Holland, Germany and Scandinavia for use by pastry cooks and restaurant keepers to make jams, liqueurs, wines, and desserts up until World War II. Bilberry’s use is not only limited to food, as the juice of bilberry yields a clear, dark blue or purplish dye that has often been used to color wool in England.
Over the years, the bilberry fruit has gained recognition for its medicinal properties. Decoctions of the leaves and bark of the root have been used for a topical application to treat mouth and throat ulcers. Syrups have also been made from a mixture of the berries and honey to treat intestinal issues.
Additionally, the berries are very rich in vitamin C, with their astringent action explaining their historical use for diarrhea and dysentery. Many believe that the berries contain a pigment that can kill many strains of bacteria. Bilberry fruit and tea that are dried have been used to treat nausea as well as indigestion. Along with the above, other traditional applications of bilberry include inflammation of the mucous membranes in the mouth and throat, eyestrain or fatigue, and as a circulatory tonic. The leaves and berries have also been used for a homeopathic treatment of diabetes.
One of the main reasons that bilberry’s medicinal value came to attention in the Western world was because of its legendary ability to improve the nighttime vision of the British Royal Air force pilots during World War II. After consuming bilberry, it was found that they experienced improved visual acuity, making it easier to carry our nighttime bombing raids. It was also found that their eyes could adjust to darkness quicker and their vision was able to better correct after the effects of prolonged glare.
In the proceeding years, scientific research found that bilberry offered a wide range of benefits for both vision and other vascular disorders. French studies found that bilberry supplementation significantly enhanced the ability to adjust for glare and darkness. Bilberry can help to prevent compromised vision for anyone who is susceptible to eyestrain. In the last few decades, more studies have confirmed the medicinal value of bilberry for a variety of eye disorders. Bilberry is routinely used by European medical practitioners for patients with cataracts, venous insufficiency, visual disorders, peptic ulcers, capillary fragility, and even dysmenorrheal.
Finally, bilberry has a great effect on the activity of many enzymes that participate in inflammatory responses. Those who bruise easily or have trouble with capillary weakness can benefit from the anthocyanidin content of bilberry. These anthocyanidins offer many actions including: stimulating the production of collagen; protecting existing collagen stores in the connective tissue; preventing the formation and release of inflammatory compounds including histamine, prostaglandins, and leukotrines; preventing certain enzyme reactions that occur as a result of inflammatory conditions; and scavenging for free radicals to reduce cellular damage from oxidizing agents.
Bilberry Extract Is A Powerful Antioxidant That Strengthens Veins
April 12, 2008 11:06 AM
Bilberry extract is taken from the Vaccinium myrtillus, or bilberry, a small blue berry that has been used traditionally for the treatment of conditions now known to be due to inflammation and the action of free radicals on the body.
Among these is atherosclerosis, or hardening of the arteries, caused by the free radical oxidation of the low density lipids that carry cholesterol around the bloodstream, and that cause deposition of fatty plaques on the arterial walls and eventually constricts them to a stage that can cause heart failure or a stroke, depending on whether the arteries are close to the heart or in the brain.
However, additional to treating this condition, bilberry has also traditionally been used for the treatment of varicose veins and also for certain eye conditions. In fact it was during the Second World war that the Royal Air Force in Britain received reports from pilots that their night vision improved after eating bilberries. Not only their vision, but the restoration of night vision after exposure to glare.
This was extremely important to war-time pilots who had to be able to rapidly adapt their vision to fly their plane after exposure to searchlights and explosive detonations. That is the reason for anything that appeared to promote this essential adaptation to be reported.
The pharmacology of these effects have been found to be due to the anthocyanosides in which bilberries are particularly rich. Anthocyanosides consist of an anthocyanaidin backbone, to which one of either arabinose, galactose or glucose can be bound. Since bilberry contains five of these anthocyanadins, then there are fifteen different anthocyanosides in the fruit concentrate.
The area of the retina that appears to control night vision, and the transition from day to night sight, is called the epithelium which is connected with purple vision. Anthocyanosides seem to have an affinity for this part of the retina, and in so doing plays an important part in this type of vision, specifically night vision although it is also beneficial in improving day vision.
Although bilberry also contains vitamins A and C, hydroquinone and tannins, it is the anthocyanosides that provide it with its unique antioxidant properties, and also its effect upon collagen fibers. It can cross-link collagen fibers to help overcome weaknesses in the connective tissues such as cartilage, tendons and the walls of blood vessels.
Its effect as an antioxidant is to prevent the cleavage of collagen by the cyzymes that are secreted by leukocytes generated by the immune system. By preventing histamine release, and release of prostaglandins and other proteins and cells mobilized during the immune inflammatory response to the detection of foreign invasion into human tissue, anthocyanosides can help to reduce inflammation and to protect against other extreme reactions of the immune system that can harm the organism it evolved to protect.
The most powerful property of anthocyanosides are their antioxidant properties: perhaps even its only property once all of the conditions it helps to protect against are fully understood. An antioxidant combines with free radicals and destroys them. Free radicals are particularly vile chemical entities that require an electron to make them stable, and they take this electron from the nearest source. This can result in oxidation and destruction of many bodily tissues leading to premature aging, atherosclerosis, eye damage and many other problems that result from the destruction of body cells and tissue.
The various constituents that make up bilberry act in concert to scavenge the free radicals and increase the supply of oxygen to the eye. The benefits of this are in helping to prevent cataracts and glaucoma, the latter due to the effect of the anthocyanoside cross-linking effect on the structure of the collagen in the eye. It can also help in cases of macular degeneration that affects the central area of the retina which might be due to the same property of there glucoside.
Moving away from the eyes and back to the vascular system, the collagen cross-linking properties of the flavonoids, which is what anthocyanosides basically are, can help to repair damaged vein tissue by strengthening the vein walls themselves, and also by providing support for the cell membranes, or outer layers of the cells.
This in turn builds up more strength in the vein tissue below the outside walls and contributes to an overall reduction in the weakness of the vein. This in turn enables it better to withstand the internal pressure put upon it by the failure of the valve that created the problem. In this way bilberries can be used to help repair the damage done by varicose veins and improve the function of the vein in returning blood to the heart from the extremities of the legs and also to help reduce the pain and swelling of varicose veins.
In addition to these beneficial effects on the vascular system and the eyes, bilberry can also help to decrease the permeability of the blood-brain barrier to pollutants, drugs and other undesirable chemicals by improving the resistance of the capillaries in the brain to the transfer of such substances through their walls. It does so by preventing the collagen of the capillaries in the brain being degraded either by enzymes or other agents, Also, by helping to strengthen that collagen structure so that it becomes more impermeable to the larger molecules that form the pollutants.
A lesser known constituent of bilberry is myrtillin, an anthocyanoside monoglucoside that is also available in all green plants, that possesses anti-glycemic properties. What this means is that it can reduce hyperglycemia and glycosurea, and so reduce blood sugar without reducing the blood sugar level to dangerously low levels. In other words it is an ideal insulin substitute.
Native Americans used green plants for teas for centuries and were free from diabetes until the came into contact with Europeans and adopted their dietary habits. Although the case has to be proved, it appears highly likely that it was the myrtillin that kept them free from a condition that affects so many other races.
Irrespective of that, however, it is for its powerful antioxidant effect that bilberry finds its best use, and also its effects on varicose veins. However, all of the above health benefits that bilberry provides, can likely be laid at the door of the combined antioxidant effect of its vitamin C content and the anthocyanosides – including the glucoside myrtillin.
Better Vision Through Bilberries
January 17, 2008 02:20 PM
"Eat your carrots! They're good for your eyes!" Isn't this what your mother always told you? Isn't that what you learned as a kid? Well, how about re-writing that phrase? How about making it into the phrase: "Eat your bilberries!"
What is a bilberry? A bilberry is a shrub just over a foot tall. The bilberry plant possesses a fruit, the cousin of the blueberry, that is indigenous to Northern Europe. These fruits contain bioflavonoids, an antioxidant with a variety of health benefits. A thousand years ago bilberries were used to relieve diarrhea and kidney stones. Today, the bilberry sees use as a treatment and preventive measure in a variety of situations. Some of the benefits seen in the modern age include possible prevention of heart disease and macular degeneration. In fact, bilberries may help strengthen the eyes when used by people regularly who aren't suffering from any ocular conditions.
The active ingredients in the fruit are tannins, which are an astringent and anti-inflammatory. The bilberry also contains anthocyanidins, which are compounds that strengthen capillaries and improve the flow of blood through the circulatory system. These anthocyanidins also increase the body’s production of rhodopsin, which is a pigment responsible for enhanced night vision and increased adaptability to changes in light by the eye. In fact, a jam made from the fruit was used by British Royal Air Force pilots in World War II who often reported that it improved their night vision, a crucial aid in an ace pilot's career.
The anthocyanidins in the bilberry fruit are a bioflavonoid. A bioflavonoid is a substance found in plants which helps strengthen the walls of capillaries. Many bioflavonoids support human health in various ways, such as naringenin which aids in cancer prevention. Others may be useful in treating liver conditions such as cirrhosis. The variety of bioflavonoid uses is a field that is still being developed.
Bioflavonoids have an extensive history. From the previously mentioned uses for bilberries to research after World War II into the connection between bioflavonoids and vitamin C, these biologically active wonder substances are an exciting branch of health supplements. They are available in various forms for your convenience.
Bilberry extract comes in a capsule form, usually meant to be taken three times daily. The manufacturer will have instructions in case of varying dosages. Bilberry extract contains the most potent dose of bioflavonoid that the bilberry has to offer. It is this potency that makes the extract the best choice for maximum ocular benefit. But it is not the only choice, in case you are looking for another way to enjoy receiving its unique health bonuses.
Bilberry tea is also made from the dried berries or the leaves of the plant. The berries are also eaten fresh or made into jam, just like the aforementioned British pilots did. The taste of a bilberry is very similar to that of a blueberry: slightly tart, slightly sweet. It has traditionally been baked in pies and it a special treat with syrup and ginger ice cream. That's a taste worthy of the fruit's pedigree!
In the world of health supplements, the unique properties and advantages this fruit, particularly bilberry extract, make it a worthy addition to anyone's daily regimen. Maybe there's a toddler in the house who won't eat his carrots. He will get similar eye benefits by eating the sweet fruit of the bilberry plant. Perhaps a tasty dessert that packs its own reward would be a welcome addition to the dinner table. The possibilities are limitless. Try some of the fruit or extract and invest in a healthier future.
Man’s best friend may have to step a side, new research on Pomegranate released.
November 08, 2007 12:24 PM
Recently, two UCLA investigations suggest that pomegranate might do wonders for man’s reproductive tract. Scientists found the pomegranate phytonutrient ellagitannins were able to slow the growth of prostate cancer cells in laboratory experiment. A recent carefully controlled pilot study discovered that 47% of men with erectile dysfunction (ED) experienced improvement when they drank pomegranate juice regularly. Researchers attributed this to pomegranates antioxidant activity. J Agricultural & Food Chemistry 08/2007; Int’l J Impotence Research 06/14/2007.
Neurological Health and CoQ10
February 25, 2007 12:06 PM
Between 1946 and 1965, 78 million Americans were born, creating the largest number of children in U.S. history. This Baby Boom generation has greatly influenced the makeup of American society and undoubtedly w ill continue to do so. Thanks to good nutrition and health care, Baby Boomers are aging well and have an excellent life expectancy. For the first time in history, we have more people turning 60 every day, and record numbers of adults reaching their seventh decade. As a result, neurological diseases associated with aging, such as Parkinson’s disease, are becoming major health care concerns. The good news is CoQ10 has applications for neurological diseases, in addition to its better known use for cardiovascular diseases.
Q. What is CoQ10?
A. CoQ10 is a natural, fat-soluble nutrient present in virtually all cells. CoQ10 also is known as ubiquinone (existing everywhere there is human life). CoQ10 is vital to the production of adenosine triphosphate (ATP). ATP is the energy-rich compound used for all energy-requiring processes in the body.
Q. Isn’t CoQ10 a supplement for heart health?
A. Yes, it is. Because the heart requires lots of ATP to meet its high energy needs, CoQ10’s function in heart health is well understood. Numerous clinical studies have demonstrated that when individuals with heart disease take CoQ10, their symptoms improve, sometimes quite dramatically. Supplemental CoQ10 improves the heart’s pumping ability, improves blood circulation, increases tolerance to exercise, and improves the heart’s muscle tone. CoQ10 also is a powerful antioxidant and protects heart tissue from free-radical damage.
Q. How does CoQ10 affect brain health?
A. CoQ10 works in the brain the same way it works elsewhere in the body: it’s essential to ATP production. Nearly all human cells contain tiny structures called mitochondria. Mitochondria are referred to as cell powerhouses because they produce cellular energy. Depending on what each cell’s job is. There can be several thousand mitochondria in one cell. If a cell needs a lot of energy, it will have more mitochondria. This explains why heart cells contain so many mitochondria; the continual pumping of blood requires continual ATP production.
The brain also requires huge amounts of uninterrupted energy to regulate, integrate, and coordinate ongoing nervous system transmissions. To meet this need, ATP production within the mitochondria of brain cells is vital. Since CoQ10 exerts such a powerful influence on heart cells in ATP production, it was a natural progression for scientists to wonder how it affects brain cells. Brain and nervous system research led to the conclusion that the same intracellular principles apply. CoQ10 is produced in the body to assist in ATP production. Without it, ATP cannot be produced.
The most important discovery regarding CoQ10 and the brain is that CoQ10, when formulated with certain ingredients, can cross the blood-brain barrier and enter the brain’s mitochondria. If large amounts of CoQ10 can get into the brain cell’s mitochondria, its ability to make ATP is greatly enhanced.
Q. What is the blood-brain barrier and why is it important?
A. The blood-brain barrier is a unique anatomical structure. The cells that make up the blood vessels that provide blood to the brain are extremely close together. This greatly restricts what can leave the bloodstream and enter the brain. While the blood-brain barrier protects the brain and spinal cord from potentially toxic substances, it also can be a significant obstacle to therapy of central nervous system disorders. Only substances with certain solubilities or those that have a transport system can cross the blood-brain barrier to a significant degree.
Obtaining optimal absorption of CoQ10 is difficult. The CoQ10 molecule is large and inflexible. The easiest and least expensive way to increase absorption levels is with the use of harsh solvents such as propylene glycol. However, at higher doses, these types of chemicals are considered dangerous (neurotoxic) to the person with a serious neurodegenerative disease. It is more difficult, as well as more expensive (considering raw materials, research, and proper manufacturing methods) to promote absorption with less harmful alternatives. However, reputable companies ensure that their products are safe for all their customers. Look for CoQ10 products formulated with vitamin E and other safe ingredients such as Micosolle.
Nearly all CoQ10 supplements enter the bloodstream. But, only CoQ10 supplements with special formulations have been scientifically shown to enter the mitochondria and cross the blood-brain barrier.
Q. If CoQ10 is made in the body, why take supplements?
A. While CoQ10 is synthesized in the body, these levels may be insufficient to meet the body’s requirements. Researchers have discovered CoQ10 levels diminish with age and as a result of dietary inadequacies and various disease states. They also have determined some medications significantly reduce CoQ10 levels in the body.
Although CoQ10 exists in some dietary sources, it may not be realistic to obtain CoQ10 through food alone. For example, it would take approximately 3 pounds of sardines, 7 pounds of beef, or 8 pounds of peanuts to equal 100 mg of supplemental CoQ10.
Q. How does CoQ10 help people with Parkinson’s disease?
A. CoQ10 seems to have several beneficial actions in the illness. Researchers have looked at mitochondria in brain cells and determined people with Parkinson’s disease have reduced activity of Complex I in the electron transport chain. Recent research has proposed the reduced activity of Complex I interferes with the brain-signaling chemical dopamine. Stored and newly synthesized dopamine is depleted. The dopamine depletion causes nerve cell degeneration.
A recent clinical study involved 80 patients with Parkinson’s disease (both men and women). The researchers first evaluated all the participants to establish scores for basic motor skills (measuring the ability to control physical movements such as walking), mental status (whether the person was depressed or experiencing memory loss) and the activities of daily living (whether the person was experiencing difficulty with handwriting, dressing themselves, using utensils such as knives and forks, and so on). This scale is known as the Unified Parkinson’s Disease Rating Scale (UPDRS). This process is known as establishing “baseline values,” that is, the condition of the patient before receiving any treatment.
Participants were divided into 4 groups. Each group received either 300 mg, 600 mg, or 1200 mg of the special form of CoQ10, or a placebo. The researchers observed the participants for 16 months.
The results of the study showed that all the participants who received CoQ10 had smaller declines in function compared to the placebo group, but the smallest decline was experienced by the group taking the highest amount of the special form of CoQ10.
The most significant results were noted specifically in the activities of daily living scores by the people taking 1200 mg of CoQ10 daily. These people retained better ability to feed and dress themselves, speak, walk, and bathe or shower by themselves. They maintained greater independence for a longer time. Parkinson’s disease, as with other neurodegenerative diseases, robs the sufferer of their ability to control the movements of their own body and care for themselves. Supplementation with CoQ10, while not a cure, is the first intervention that showed a slowing in the progressive deterioration of the function associated with this disease.
Q. What were the results of clinical research on Huntington’s Disease?
A. A randomized, double-blind, placebo controlled study respected type of study, was conducted at the University of Rochester. All of the 347 Huntington’s disease (HD) patients were experiencing some HD symptoms, but were still in the early stages of the disease. The patients (who did not know which drug they were receiving) were randomly assigned to four different treatment groups: 25 percent received Remacemide, 25 percent received CoQ10, 25 percent received both, and 25 percent received a placebo, or sugar pill. The researchers, who also did not know which patients got which drug, watched and recorded their progress for two and one-half years. Remacemide is a new drug made by Astra Seneca that blocks the neurotransmitter glutamate in the brain, that has long been suspected of contributing to the death of brain cells in Huntington’s disease.
Unfortunately, in the CARE-HD study, Remacemide had no effect on the progression of the disease in patients in the early stages. However, the individuals who received 600 mg of CoQ10 per day experienced some slowing of the disease progression. They were able to manage daily activities, such as meal preparation, housekeeping tasks, and personal care longer than those not on CoQ10. They were also able to focus their attention better and were less depressed and irritable. The portion of the studied patients receiving 600 mg of CoQ10 per day experienced a 15 percent decline in the progression of HD. According to the researchers conducting the study, a 15 percent decline in the progression of HD would roughly translate into approximately one more year of independence for patients. This is the very first study from more than a dozen Huntington’s disease patient trails that showed any modification of the course of the illness.
Of note, the effects of the CoQ10 had not abated at the end of the research study. That is, the benefit of using CoQ10, 600 mg per day, was still increasing; this suggests that the longer a patient supplements with CoQ10, the greater the decline in the progression of HD. The next phase of the CARE-HD research will test a higher dose of CoQ10 (1200 mg or more per day), with more patients (over 1000), for a longer period of time (approximately 5 years). This study should improve our understanding of the optimal dose and the total achievable decline in the progression of HD. The CoQ10 product used in the CARE-HD study was designated an Orphan Drug by the FDA. The product utilizes a proprietary, patent-pending delivery mechanism, which is proven to be safe and tolerable at high doses for people suffering from neurodegenerative diseases, substantially improving brain tissue levels of CoQ10.
Q. What other diseases could benefit from CoQ10 supplementation?
A. Studies show CoQ10 levels are greatly reduced in Alzheimer’s patients. Mitochondrial abnormalities also are noted; however, research has yet to determine how or why this occurs. Some scientists believe damage to mitochondria is an early feature of the disease. Free-radical damage also is a feature of Alzheimer’s.
In a study of 27 Alzheimer’s patients, subjects were given 60 mg of CoQ10, 150 mg of iron, and 180 mg of vitamin B6 daily. Each patient’s mitochondria activity was effectively activated. All patients continued to experience gradual decline. However, researchers believed that with this combination, the progression was much slower and allowed the patients to experience 1 to 2 years of extended good health.
ALS (also known as Lou Gehrig’s disease) is a progressive, fatal, neurological disease. It occurs when the nerve cells in the brain that control voluntary movement gradually degenerate. Investigation of CoQ10 in individuals with ALS is just beginning. Researchers at the Eleanor and Lou Gehrig ALS Center at Columbia University recently conducted a small clinical pilot trial of CoQ10 in ALS. The study was an open label study, which meant that everyone enrolled received CoQ10, 400 mg three times per day. Of the 16 patients originally enrolled, nine patients completed the study. Six of these nine patients experienced some benefits. The patients declined from 0 – 25 percent in functional scores, 6 percent in strength, and 10 percent in breathing ability. These scores reflect a positive trend compared to the 50 percent decline that is seen in the natural history of ALS over the same period of time (5 to 9 months). Citing the need to conduct more studies of the effectiveness of CoQ10 for people with ALS is rapidly and efficiently as possible to get answers to patients and clinicians, another clinical trial is currently underway at the Gehrig ALS Center. This is a pilot study to determine if CoQ10 has short-term effects on motor nerves in the brain using magnetic resonance spectroscopy (MRS). The researchers are going to try to “see” if CoQ10 can change the chemical sin the brain’s upper motor nerves of people with ALS, an important next step of the investigation.
Q. Can taking CoQ10 prevent neurodegenerative disease?
A. To date, there have been no studies or research examining whether CoQ10 can prevent these diseases.
Alzheimer’s disease prevention is being clinically investigated. Researchers have determined that people who take certain anti-inflammatory medications seem less likely to develop the illness. A large, multi-centered trial is studying this connection.
Q. How much CoQ10 should I take?
A. Depending on your family history of neurological disease and your disease experience, studies show benefits at doses of 100 to 200 mg of CoQ10 daily. Some studies used doses of up to 1,200 mg per day.
CoQ10’s safety has been evaluated. To date, no toxicities have been reported. Mild stomach upset may occur. Taking CoQ10 with meals usually alleviates this rare effect.
Q. What should I look for in a CoQ10 supplement?
A. Use products which have a strong clinical research track record, supported by product-specific research from reputable institutions, and have been proven to be safe, tolerable and effective in treatment of neurodegenerative diseases. The CoQ10 product you choose should be proven to: be absorbed, enter the blood stream, cross the blood brain barrier and increase mitochondrial levels of CoQ10. If the product you are considering does not have evidence to support these points, keep looking. Once you have found a candidate, examine the product’s safety and efficacy record for neurodegenerative diseases- if the product has not been proven to be safe and effective, keep looking. Good products exist; however, caveat emptor.
CoQ10 supplementation for people with neurodegenerative diseases is supported by contemporary clinical research. CoQ10 is certainly not the only answer to the complex issues of management and treatment of these types of diseases. However, research indicates that it is a bigger piece of the puzzle than physicians and scientists ever imagined. As we continue to study this naturally occurring compound, we are finding more and more benefits to the body.
All CoQ10 is not created equal. For safety and overall effectiveness, use a CoQ10 product that is supported by product-specific research from reputable institution, which is proven to be safe, tolerable and effective at high doses; deviating from this set of criteria may do more harm than good for people with these serious illnesses. Choose clinically tested products from a well-respected company and increase the potential to achieve and maintain brain and neurological health.
Remifemin symptomatic relief, scientifically supported*
August 26, 2006 02:41 PM
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Lit source: Enzymatic therapy.
*this statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treate, cure, or prevent any disease.
The Childhood Obesity Epidemic
August 09, 2006 04:57 PM
The Zimmerman File: Marcia Zimmerman, CN, is a respected author and educator in the field of health and nutrition.
Fighting Obesity – What do I put in my child’s Lunch?
We begin the 21st century with a startling setback in life expectancy for our youth. Some experts even fear that today’s kids may not live as long as their parents. That’s despite the recent advances in medicine that have been credited with extending life span.
The Childhood Obesity Epidemic
The obesity epidemic is occurring in boys and girls in all 50 states. It’s happening in younger children as well as adolescents, across all socioeconomic strata, and among all ethnic groups. At a time when we have learned that excess weight has significant and troublesome health consequences, we see our children gaining weight to a dangerous degree and at an alarming rate. According to a 2004 report from the Centers for Disease Control, the number of over weight 6 to 11 year olds more than doubled in the past 20 years—going from 7 percent in 1980, to 18.8 percent in 2004. the rate among adolescents between 12 to 19 more than tripled, increasing from 5% to 17.1%.
An estimated 61% of overweight young people have at least one additional risk factor associated with becoming overweight. These include heart disease, high cholesterol or high blood pressure—factors that have been traditionally associated with much older adults. In addition, children who are overweight are at greater risk for bone and joint problems, sleep apnea, and social and psychological problems such as stigmatization and poor self-esteem. Overweight young people are more likely than their normal weight peers to become over weight of obese adults, adding additional risk factors such as stroke, several types of cancer, and osteoarthritis.
The consensus among pediatricians, school administrators, parents, and government officials is that healthy lifestyle habits, including healthy eating and physical activity, can lower the risk of becoming overweight and developing related diseases. Associated problems with a growing overweight population are reduced productivity, increased disability, and a greater number of overweight individuals requiring nursing home care as they move into retirement. Clearly the centerpiece of reducing childhood obesity is to reduce its health related and economic costs.
Clearly, we must tackle this problem head-on in order to save our youth. It is beginning as a grass roots movement in the classroom and will involve nutritionists, enlightened teachers, pediatricians, natural food retailers, manufacturers and suppliers of healthy foods. Beginning in the opening weeks of school 2006-2007, a pilot program to teach 6th graders how to eat for better health will be instituted in Chico, California. As the program is perfected, it will be offered nationwide. This is how the plan unfolds.
Show kids how
Breakfast: Cereals, Whey Protein Powders, with Glutamine added, add Malted Milk Powder to any shake, for a change.
Lunchbox: Dried fruits (non-sulfite), Nuts, Seeds, and Organic Popcorn.
Health Snack Bars Nuts & Seeds, Organic Fruit Bars, Organic Virta Raw Sprouted Bars.
Dinner: Grains, Textured Soy Protein, Oils.
Vitamins: (very important to keep kids healthy and at the top of their game) Daily Multiple: Kid Vits berry Blast or Orange Splash, daily vits easy-to-swallow tabs for older kids, Effer-C Packets, Omega-3 Fish Oil; (for brain nutrition)
Oral Hygiene: (don’t forget the anti-caries power of xylitol)
XyliWhite Fluoride-Free Refreshmint Toothpaste XyliWhite Fluoride-Free Cinnafresh Toothpaste XyliWhite Fluoride-Free Refreshmint Mouthwash XyliWhite Fluoride-Free Cinnafresh Mouthwash
Mary Travis at Now Foods has been collecting amazing recipes that use Now Foods ingredients. Contact her at firstname.lastname@example.org for more information.
Best Sugar Balance Svetol (green coffee extract)
May 05, 2006 06:30 PM
Best Sugar Balance featuring Svetol® Svetol® is an extract of green coffee obtained by the use of a traditional patented extraction process from the beans of the species Coffea canephora robusta Pierre. This species is particularly rich in the constituent known as chlorogenic acid. Svetol® green coffee extract contains less than 2% caffeine. The extract is standardized to contain between 45-50% chlorogenic acids.
In vitro (test tube) and in vivo research suggests that chlorogenic acids present in coffee may have the ability to regulate blood sugar concentrations after meals by acting on the intestinal absorption of glucose and improving the body's glucose tolerance. Clinical evidence also suggests that Svetol® green coffee extract may help to maintain a healthy blood sugar level when used as a part of the diet.*
Maintains healthy blood sugar levels when used as a part of the diet*
Chlorogenic acid is the major polyphenol compound found in Svetol® green coffee bean extract. In vitro and animal studies have been conducted to determine the potential actions of this polyphenol. Studies report that chlorogenic acid and related compounds have significant antioxidant potential and are responsible for the high reported antioxidant benefit of green coffee. Several studies suggest that consumption of coffee in the diet is one factor that is correlated to the maintenance of healthy neural function and healthy aging. Coffee has also been shown in vitro to suppress the production of various free radicals. The chlorogenic acid content of coffee has been determined to be a major factor in the free radical quenching properties of coffee. A study was conducted to assess the activity of coffee extracts against the production of hydroxyl radicals in an in vitro system. It was found that coffee extracts possessed significant suppressive activity against hydroxyl radicals. Of the compounds assumed to be responsible for this effect, the researchers concluded that the chlorogenic acids played a major role with some contributions from other compounds found in the extract. This compound may also strongly contribute to any potential neuroprotective effects seen with coffee consumption.1
Two further studies highlight a possible mechanism by which chlorogenic acid mediates its antioxidant activity. In one study, the FRAP (Ferric Reducing Antioxidant Power) assay was used to measure and compare the iron-reducing capacity of chlorogenic acid and caffeine. It was shown that the chlorogenic acid content of the samples tested was highly correlated with iron-reducing activity in this assay. Moreover, lighter roasted coffee samples (closer in nature to green coffee) had the highest iron-reducing activity. Caffeine did not influence the iron-reducing activity of the coffee samples.2 Iron compounds are known to mediate the production of radicals and often serve as catalysts for their production in the body. A second study shows that chlorogenic acid can bind to and Chelate certain iron compounds, preventing them from catalyzing radical-producing reactions. In this way, chlorogenic acid acts as a powerful antioxidant.3
Chlorogenic acid and related compounds have a dual effect on the production and suppression of free radicals. In the case of the hydroxyl radical, studies outlined previously suggest that chlorogenic acid suppresses the production of the radical due to its ability to chelate iron compounds, while other studies suggest that chlorogenic acid has direct scavenging effects on the hydroxyl radical.4 Dietary intake of this potent polyphenol may confer multiple benefits to human health.
Several studies further suggest that chlorogenic acid in coffee can have a beneficial effect on blood sugar levels when consumed as a part of the diet. A recent study assessed the effects of coffee and tea consumption on glucose tolerance in middle-aged Japanese men. In this study, the relationship between daily intakes of green tea or coffee and glucose tolerance status was measured by the oral glucose tolerance test (OGTT). More than 3,400 men participated in the study in which fasting glucose was measured before and 2 hours after administration of an oral glucose load. A self-administered questionnaire was used to establish daily levels of dietary coffee and green tea consumption over the past year. The results showed that those individuals who consumed the highest levels of coffee per day had lower fasting glucose levels (by 1.5%) and lower post-test glucose concentrations (4.3% lower) than those who did not consume coffee Chlorogenic acid and related compounds have a dual effect on the production and suppression of free radicals. In the case of the hydroxyl radical, studies outlined previously suggest that chlorogenic acid suppresses the production of the radical due to its ability to chelate iron compounds, while other studies suggest that chlorogenic acid has direct scavenging effects on the hydroxyl radical.4 Dietary intake of this potent polyphenol may confer multiple benefits to human health.
Several studies further suggest that chlorogenic acid in coffee can have a beneficial effect on blood sugar levels when consumed as a part of the diet. A recent study assessed the effects of coffee and tea consumption on glucose tolerance in middle-aged Japanese men. In this study, the relationship between daily intakes of green tea or coffee and glucose tolerance status was measured by the oral glucose tolerance test (OGTT).
More than 3,400 men participated in the study in which fasting glucose was measured before and 2 hours after administration of an oral glucose load. A self-administered questionnaire was used to establish daily levels of dietary coffee and green tea consumption over the past year.
The results showed that those individuals who consumed the highest levels of coffee per day had lower fasting glucose levels (by 1.5%) and lower post-test glucose concentrations (4.3% lower) than those who did not consume coffee on a daily basis. In this study, green tea consumption was not associated with any benefits on glucose concentrations.5
It is likely that the chlorogenic acid found in coffee plays a role in supporting healthy glucose metabolism, whereas the role of caffeine is not clear, with some reports suggesting an adverse effect on sugar metabolism.
A second study further confirms an effect of chlorogenic acid at inhibiting the absorption of glucose from the diet. This effect occurs in the small intestine. In this study, nine healthy fasted volunteers consumed 25 grams of glucose in 400 ml of water (the control group), caffeinated coffee, or decaffeinated coffee. Frequent blood samples were taken over the next 3 hours. It was found that glucose and insulin concentrations were higher 30 minutes after the consumption of caffeinated coffee than with either decaffeinated coffee or control (water).While caffeine has specific biological effects on raising glucose levels and impacting insulin profiles, chlorogenic acid was shown to have an antagonistic effect on glucose transport. Previous studies have also shown that chlorogenic acid significantly delays glucose uptake from the small intestine.6
RESEARCH ON SVETOL®
Svetol® is a unique extract of Coffea canephora robusta green coffee beans containing between 45 and 50% chlorogenic acids with less than 2% total caffeine concentration. As outlined above, many studies highlight the potential benefits of coffee compounds, including chlorogenic acid, for providing protection against free radicals and promoting healthy glucose metabolism. A number of other potential benefits have been discovered for these compounds. Svetol® has also been the subject of preliminary clinical studies that have shown exciting results.
In a pilot study, the effect of Svetol® on sugar concentrations after meals was evaluated in 15 individuals. In the same trial, the longer-term effects of Svetol® on weight management were also evaluated. Blood sugar concentrations were measured on two separate occasions. Patients were administered an oral glucose tolerance test (OGTT) in which they consumed a standard amount of sugar and had their blood sugar levels measured 1 hour after sugar intake. The first measurement was made on day 1 prior to taking Svetol® and the second OGTT was performed on day 2, after beginning the Svetol® regimen in which one tablet (200 mg per tablet) was administered 3 times during the day. Patients were fasted for at least 8 hours prior to the testing. The results showed that Svetol® was able to reduce blood sugar concentrations in 60% of the subjects. The mean reduction of blood sugar concentration in these individuals was 50%. The treatment was continued following the same regimen for 6 weeks to assess the impact of Svetol® on weight. The average weight loss of the participants was 1.5 kg (3.3 lbs) over the treatment period. 7
Based on the studies mentioned above and other related research on the ingredients in Svetol®, scientists have proposed two mechanisms of action whereby Svetol® may influence the metabolism and processing of glucose. The first mechanism seems to be an inhibitory action on glucose absorption from the diet. Svetol® may affect the uptake of glucose in the small intestine by modulating factors needed for sugar absorption.
The second mechanism relates to possible effects of Svetol® in the liver's ability to produce glucose. Chlorogenic acids have been shown in vitro and in animal studies to modulate the effects of certain enzymes in the liver that catalyze the production of glucose. By having this dual effect on sugar absorption and sugar production, Svetol® is an effective product for maintaining healthy blood sugar levels when used as a part of the diet.*
Svetol® is a natural food extract from green coffee beans containing a standardized amount of chlorogenic acid. Studies have shown that chlorogenic acid (up to 500 mg/kg/day) given to pregnant rats from the 5th through 12th day of gestation caused no maternal or fetal mortality and no adverse effects on the nervous system. Chlorogenic acids have also been shown to be non-mutagenic in tests on bacteria such as the Ames test. The LD50 of chlorogenic acids has been determined to be higher than 2500 mg/kg body weight. Svetol® is also extremely low in caffeine, with less than 2% caffeine contained in the extract, and is not expected to have any of caffeine's stimulant effects. Svetol® is extremely safe with no adverse effects having been reported while taking Svetol® at the recommended dosage.7
*This statement has not been evaluated by the Food and Drug Administration.This product is not intended to diagnose, treat, cure or prevent any disease.
1) Daglia M, Racchi M, Papetti A, Lanni C, Govoni S,Gazzani G. In vitro and ex vivo antihydroxyl radical activity of green and roasted coffee. J Agric Food Chem.2004 Mar 24;52(6):1700-4.
2) Moreira DP, Monteiro MC, Ribeiro-Alves M, Donangelo CM, Trugo LC. Contribution of chlorogenic acids to the iron-reducing activity of coffee beverages. J Agric Food Chem. 2005 Mar 9;53(5):1399-402.
3) Kono Y, Kashine S,Yoneyama T, Sakamoto Y, Matsui Y, Shibata H. Iron chelation by chlorogenic acid as a natural antioxidant. Biosci Biotechnol Biochem. 1998 Jan;62(1):22-7.
4) Zang LY, Cosma G, Gardner H, Castranova V, Vallyathan V. Effect of chlorogenic acid on hydroxyl radical. Mol Cell Biochem. 2003 May;247(1-2):205-10.
5) Yamaji T, Mizoue T, Tabata S, Ogawa S, Yamaguchi K, Shimizu E, Mineshita M, Kono S. Coffee consumption and glucose tolerance status in middle-aged Japanese men.Diabetologia. 2004 Dec;47(12):2145-51. Epub 2004 Dec 15.
6) Johnston KL, Clifford MN, Morgan LM. Coffee acutely modifies gastrointestinal hormone secretion and glucose tolerance in humans: glycemic effects of chlorogenic acid and caffeine. Am J Clin Nutr. 2003 Oct;78(4):728-33.
7) Berkem.Text on Svetol®.Gardonne, France: November 2005.
HDL Booster - Boost your good cholesterol
March 16, 2006 12:51 PM
(Product No. 02922)
HDL Booster is a physician-developed dietary supplement that has been clinically shown to increase good cholesterol levels, particularly HDL-2, the best form of cholesterol.* The formula combines essential vitamins and minerals, at levels recommended by the American Heart Association (AHA), with key amino acids, powerful antioxidants, and traditional herbal extracts to provide superior support for cardiovascular health.*
<![if !supportLists]>· <![endif]>Formulated by Dr. Dennis Goodman, Chief of Cardiology at
<![if !supportLists]>· <![endif]>Clinically studied to increase good cholesterol levels up to 23%*1
<![if !supportLists]>· <![endif]>All-inclusive formula; includes ingredients recommended in accordance with the American Heart Association
<![if !supportLists]>· <![endif]>Replaces the CoQ10 depleted by cholesterol lowering (statin) drugs.*2
HDL Booster has been clinically shown to increase HDL cholesterol levels.* HDL Booster also supports healthy cholesterol and healthy triglyceride levels already within the normal ranges.* By reducing C-reactive protein levels, HDL Booster helps support the body’s natural anti-inflammatory response.*
Two tablets (one serving) contain:
Vitamin C (ascorbic acid) 148 mg
Vitamin E (as natural mixed tocopherols) 35 IU
Niacin (as niacinamide) 21 mg
Vitamin B6 (as pyridoxine HCl) 3 mg
Folic Acid 301 mcg
Vitamin B12 (as cyanocobalamin) 20 mcg
Magnesium (from magnesium amino acid chelate) 10 mg
Selenium (as L-selenomethionine) 49 mcg
Proprietary Blend 388 mg
hawthorn (Crategus oxyacantha) berry extract,
taurine, garlic (Allium sativum) bulb, grape seed (Vitis
vinifera) extract, grape skin (Vitis vinifera) extract,
N-acetyl-L-cysteine, alpha-lipoic acid, soy (Glycine
max) isoflavones, tocotrienols
L-Arginine (as L-arginine HCl) 153 mg
L-Carnitine (as L-carnitine L-tartrate) 51 mg
Coenzyme Q10 (CoQ10)(ubiquinone 10) 25 mg
Policosanol 7 mg
Other ingredients: See label for most current information.
Contains no: sugar, salt, yeast, wheat, gluten, corn, dairy products, artificial coloring, artificial flavoring, or preservatives. This product contains natural ingredients; color variations are normal.
Cholesterol, the soft, waxy substance present among the lipids (fats) in the bloodstream and in all cells, is important for wide variety of physiological functions. It is essential for the formation of cellular membranes, necessary for the production of bile salts, and also plays a role in the synthesis of certain hormones.3-5
Cholesterol is both produced by the body and obtained from food. Endogenous cholesterol is formed by human cells, particularly liver cells, whereas exogenous cholesterol is absorbed through the gastrointestinal tract from food.3,4
Because cholesterol can not be metabolized for energy, it must be removed from the body once it has served its function. The major route of removal is through the liver, where it is processed and subsequently excreted from the body.3,4
Types of Cholesterol
Cholesterol is lipophilic (“fat loving” or water insoluble) by nature. It can not be dissolved in the blood, and must, therefore, be transported by carriers known as lipoproteins. These carriers are classified by density, with LDL (low density lipoproteins) and HDL (high density lipoproteins) being the most common.4,5
LDL is often referred to as “bad” cholesterol. LDLs carry cholesterol throughout the body. Conversely, HDL, or “good” cholesterol, is responsible for carrying cholesterol away from the arteries to the liver where it is eventually processed and eliminated from the body.3,4,6
Scientific studies have shown that both types of cholesterol are important indicators of cardiovascular health. But recent research, focusing on the beneficial subtypes of HDL, has found that certain fractions of HDL may be more supportive of cardiovascular health than others. The two most notably supportive HDL fractions are HDL-2 and HDL-3.7
The smaller HDL-3 is synthesized by the liver and intestines. This form, which is known as “free cholesterol-rich” HDL, scavenges or “scoops up” free cholesterol. The cholesterol is then chemically altered by the addition of an ester group. When sufficient cholesterol is esterified, HDL-3 becomes HDL-2, which is therefore referred to as “cholesterol ester-rich” HDL. HDL-2 is larger in size and has been shown to be more cardiosupportive than HDL-3.*7
HOW IT WORKS:
HDL is known to possess antioxidant activity and to help balance the body’s natural anti-inflammatory response, both of which are important for cardiovascular health, but its most important function is the role it plays in cholesterol transport.6,8 High levels of HDL cholesterol are also associated with reduced platelet activity, another key indicator of arterial and venous health.9
Both HDL and LDL levels are important indicators of healthy cardiovascular function.* Therefore, supplements that increase the level of good cholesterol can profoundly impact heart health.* In 2002, an open label pilot study was conducted at
The following chart summarizes the benefits of each of the ingredients in HDL Booster:
Benefits of Best Alpha Lipoic 35!
February 12, 2006 03:11 PM
Nattokinase Fact Sheet
December 08, 2005 05:14 PM
Nattokinase Fact SheetNeil E. Levin, CCN, DANLA 8/8/05
LIKELY USERS: People seeking to support heart health and healthy circulation.1-6
KEY INGREDIENTS: Nattokinase, an enzyme
STRUCTURE/FUNCTION USE: Nattokinase is an enzyme isolated from Natto, a traditional Japanese fermented soy food. Natto has been consumed safely for thousands of years for its numerous health benefits. More recently, both clinical and non-clinical studies have demonstrated that Nattokinase supports heart health and promotes healthy circulation. Each serving of NOWR Nattokinase provides 2,000 FU (Fibrinolytic Units) to help keep already healthy levels of blood clotting factors within a normal range. 1-6
ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: An assay of 2,000 FU (Fibrinolytic Units) is equivalent to 160 IU on the Urokinase assay. The FU assay measures Nattokinase activity by using the fibrin plate method and measuring the absorption of released low-molecular weight substances.7 NOW Nattokinase is made from non-GE (non-genetically engineered) bacteria (Bacillus subtilis var. Natto) grown on non-GE soybeans and standardized on a base of non-GE, corn-derived maltodextrin.
SERVING SIZE & HOW TO TAKE IT: Take one vegetarian Vcap once or twice a day between meals (without protein).
COMPLEMENTARY PRODUCTS: Vein SupremeTM, Tru-E Bio ComplexTM, Pycnogenol®, garlic, and cayenne
SPECIFIC: People with blood coagulation disorders or who take anticoagulant (“blood thinning”) medications (including aspirin) should consult a physician before use. Do not take if prone to bleeding. Unlike some other brands, NOWR Nattokinase contains no Vitamin K (K1 or K2), which would enhance clotting.
GENERAL: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. Information given here may vary from what is shown on the product label because this represents my own professional experience and understanding of the science underlying the formula and ingredients. When taking any new formula, use common sense and cautiously increase to the full dose over time.
Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
1. Fujita M, Hong K, Ito Y, Fujii R, Kariya K, Nishimuro S (1995) Thrombolytic effect of nattokinase on a chemically induced thrombosis model in rat. Biol Pharm Bull 18(10):1387-1391
OsteoBoron™ Fact Sheet
December 08, 2005 05:09 PM
OsteoBoron™ Fact SheetNeil E. Levin, CCN, DANLA 8/8/05
LIKELY USERS: People looking for joint support; People looking for bone density support; People who want to normalize Vitamin D levels
KEY INGREDIENTS: FruiteX-B™
STRUCTURE/FUNCTION CLAIMS: Boron is an important trace mineral for bone and joint health throughout life, as well as for the development and maintenance of healthy bone density. 1,2,4,6,8,9 NOW® OsteoBoron™ is a patented (US Patent # 5,962,049) complex of Boron and Fructose that is safe and more bioavailable than other forms of Boron. 3,7 NOW® OsteoBoron™ is a superior form of Boron that has been the subject of clinical studies demonstrating its efficacy in the support of healthy joints. 7,10 NOW® OsteoBoron™ has also been shown to be safer than other Boron supplements. 3,7
ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES:
FruiteX-B™ is a patented ingredient that contains boron in a form that is chemically identical to the natural plant forms of boron found in food (Calcium Fructoborate). In human and animal studies this patented form of boron, taken at an amount equal or equivalent to 6 mg. per day, improved bone ash (bone minerals) and Vitamin D status in Vitamin D deficient subjects. In human studies, measurements of joint discomfort were dramatically reduced when taking this dosage for about 2 months. The dose used in most of these studies was equivalent to 2 capsules a day of NOW® OsteoBoron™, a form that has been shown to be biologically more beneficial than other forms of boron.11
SERVING SIZE & HOW TO TAKE IT: One vegetarian capsule twice a day, preferably at separate meals. This dose can be doubled for people with more severe deficiencies, though a physician should normally be consulted in such cases.
COMPLEMENTARY PRODUCTS: Vitamin D, Calcium, Magnesium, copper, Silica/silicon, natural sources of phytoestrogens (plant sourced), Ipriflavone, Bone Strength or Bone Calcium formulas
SPECIFIC: Please note any supplements currently consumed which may also contain boron, such as multiple mineral or multiple vitamin formulas, and cut your serving size of NOW® OsteoBoron™ to compensate. People who eat a lot of produce, fruit and nuts may also get a substantial amount from their food and may want to reduce their servings of NOW® OsteoBoron™ accordingly. NOW® OsteoBoron™ is safer (has less toxicity) than boron citrate. Boron may buffer body levels of estrogen, so women at risk from high estrogen should consult a physician before using NOW® OsteoBoron™, even though this problem has not been noted for food source borons.
GENERAL: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. This document has not been reviewed by the FDA or by the company posting it. Information given here may vary from what is shown on the product label because this represents my own professional experience and understanding of the science underlying the formula and ingredients. When taking any new formula, use common sense and cautiously increase to the full dose over time.
Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
1. Shils ME, Olson JA, Shike M (eds.) (1994) Modern Nutrition in Health and Disease, Eighth Edition. Chapters 20-26, 28, 30. Lea & Febiger Philadelphia.
Benefits of Alpha Lipoic Acid
October 13, 2005 05:08 PM
Benefits of Alpha Lipoic Acid
Alpha-lipoic Acid––the "Ideal Antioxidant"
The antioxidant potential of a substance is based on a number of criteria, including:
The "ideal antioxidant" would meet all the above criteria. Very few antioxidants do, yet a particular antioxidant with but a few of the characteristics is still valuable and effective. Vitamin E, for example, is one of the most important dietary antioxidants, yet it only works in fatty environments such as cell membranes.
As a team, ALA and DHLA come close to the ideal, for the following reasons:1,2,3
DHLA-regenerates vitamin C, vitamin E and glutathione
Within the cell, antioxidants work as a team to keep free radicals from damaging cell structures. In order to neutralize a free radical, an antioxidant such as vitamin C must give up an electron, which mean it becomes oxidized. Before it can function as an antioxidant once again, it must be regenerated back to its "reduced" form, by gaining an electron to replace the donated electron. For this, it needs the help of other antioxidants. Vitamin C, vitamin E and glutathione are key antioxidants that can be generated by cycling between their oxidized and reduce forms. This is necessary to maintain the balance between oxidation and its reverse––the neutralization of free radicals by antioxidants.
DHLA is an essential component in the interaction between these antioxidants.4 Studies show that addition of alpha-lipoic acid to liver tissues results in increased vitamin C levels. It has been found that DHLA is responsible for regenerating vitamin C, which in turn regenerates vitamin E.3 DHLA also converts glutathione from its oxidized form back into its free radical scavenging reduced form.3,5 The ALA/DHLA pair is thus vital for prevention of "oxidative stress," which occurs which the balance is tipped in favor of oxidation in cells.4 DHLA helps preserve antioxidants in both the watery cell interior and the fatty structure of cell membranes.6 Evidence from animal studies suggests that DHLA protects the brain against free radical damage.7
Alpha-lipoic Acid and Blood Sugar
Alpha-lipoic acid is a key factor in the cellular process that metabolizes glucose to produce energy for cellular functions. The importance of ALA’s role in blood sugar metabolism is evidenced in studies on ALA and type-2 diabetes. In a small pilot study, 13 people with type-2 diabetes showed improved utilization of glucose in muscle tissue in response to intravenous administration of ALA.8 In a four week controlled multicenter trial, 74 people with type-2 diabetes took ALA in oral doses of 600, 1200 or 1800 mg per day. After 4 weeks, the normal lowering of blood sugar levels in response to insulin improved.9 In vitro studies have shown that ALA has a positive effect on insulin-stimulated uptake of glucose by muscle cells.10
1. Packer, L.. Witt, E., Tritschler, H. Alpha-lipoic acid as a biological antioxidant. Free Radical Biology and Medicine 1995;19(2):227-50.
2. Suzuki, Y., et al. Thioctic acid and dihydrolipoic acid are novel antioxidants which interact with reactive oxygen species. Free Rad. Res. Comms. 15(5):255-63.
3. Biewenga, G., Haenen, G., Bast, A. The pharmacology of lipoic acid. Gen. Pharmac. 29(3):315-31.
4. Serbinova, E. Maitra, I., Packer, L. The synergy between vitamin E and alpha-lipoic acid--–possible relationship against oxidative stress in vivo. Life Chemistry Reports 1994;12:17-21.
5. Bast, A. Haenen, G. Interplay between lipoic acid and glutathione in the protection against microsomal lipid peroxidation. Biochimica et Biophysica Acta 1988; 963:558-561.
6. Kagan, V. et al. Dihydrolipoic acid––a universal antioxidant both in the membrane and in the aqueous phase. Reduction of peroxyl, ascorbyl and chromanoxyl radicals. Biochem Pharmacol 1992;44(8):1637.
7. Prehn, J. et al. Dihydrolipoate reduces neuronal injury after cerebral ischemia. J Cereb Blood Flow Metab 1992;12(1):78-87.
8. Jacob, S. et al. Enhancement of glucose disposal in patients with type-2 diabetes by alpha-lipoic acid. Arzneimittelforschung 1995;45(8):872-4.
9. Jacob, S et al. Oral administration of RAC-alpha-lipoic acid modulates insulin sensitivity in patients with type-2 diabetes mellitus: a placebo-controlled pilot trial. Free Radical Biology & Medicine 1999;27(3/4):309-14.
10. Estrada, D. et al. Stimulation of glucose uptake by the natural coenzyme alpha-lipoic acid/thioctic acid: participation of elements of the insulin signaling pathway. Diabetes 1996;45(12):1798-804.
Cuddlin’ in the Kitchen
July 27, 2005 03:44 PM
Cuddlin’ in the Kitchen
You and your sweetie can turn up the heat by cooking together.
Since the beginning of time, the pleasures of the table have been intertwined with those of the boudoir. (Remember the scene in the film Tom Jomes in which Tom and his amorata-of-the-moment wolf down a meal while staring lustily into each other’s eyes?) But when most of your kitchen time is spent trying to get everyone fed and out of the house in time for the night’s soccer game/ PTA meeting/ballet lesson, it can be tough keeping the pilot light lit on your love.
That’s why one of the best ways to spice up your sex life is to prepare a sensuous meal together sans offspring (thank heavens for doting grandparents with spare rooms!). A little fourhanded cooking- preferably while sharing some suggestive banter- can create chemistry that allows your playful, non-parenting side s to emerge, enhancing intimacy and setting the stage for the seductive feast to follow.
Just as the frenzied pace of modern living can often foster a sense of separation, cooking together as a couple can promote a sense of union. “Eventually you get a feel for your partner’s rhythms and adjust yours accordingly,” says food TV personality Jacqui Malouf, author of Booty Food (Bloomsbury). “Before you know it you’re passing the coriander, peeling the potatoes and stirring the risotto at precisely the right moments.”
With time, you can learn what each of you does best: Who has a flair for combining spices in just the right proportions? Who can chop carrots into perfect little matchsticks without taking all night? Since nothing kills the mood more than arguing over who misplaced the baker’s chocolate or the pasta platter, buy your ingredients earlier in the day and have all the necessary utensils out and at the ready. (Safety note: while two in a tiny kitchen can be steamily cozy, do be careful with hot pots and sharp knives.)
Four hands can also be better than two, so why not make the most of it? Malouf suggests approaching your combined efforts with a sense of adventure: “Use more than three ingredients in a salad dressing! Be daring with your desserts! Try concocting something with squab or squid or quince or quail- the sky’s the limit.”
One advantage of using exotic ingredients (or at least foods not normally found on your weekly shopping list) is that they can help you and your partner break through the limits of everyday experience by reawakening long-dormant senses. Go ahead- run your fingertips over the rough rind of a pomegranate before feeling the smooth, full seeds within. Inhale the sweet, perfumed scent of a dead-ripe apricot, and appreciate its downy skin. Admire the cool green beauty of a cut avocado, and share a spoonful with your sweetie.
Avocado, in fact, is one of the foods known for inflaming passion based on its suggestive shape, along with artichoke and asparagus- and that’s just the AS! (Chocoholics rejoice: Chocolate, full of the same feel-good chemical released by the brain when one falls in love, also makes the ecstasy encouraging grade, even when obtained in standard shapes.) “coincidentally, many foods long considered aphrodisiacs are low in fat (avocado and chocolate are delectably healthy exceptions) and are high in vitamins and minerals,” write Martha Hopkins and Randall Lockridge in Intercourses: An Aphrodisiac Cookbook (Terrace Publishing). “A diet heavy in these foods, then, yields a healthy blood healthy body with the energy, blood flow and nutrients needed for a peak sexual experience.” (The way these foods feed the imagination- the ultimate smorgasbord of pleasure- is a bountiful bonus.) Other foods, such as honey, have been treasured for supplying the energy needed to fan love’s flames far into the night; no wonder the sweet, sticky stuff shows up in a number of naughty-night concoctions.
Just as Venus, the Roman goddess of love, emerged fully formed from the sea, so do the foods that best encourage those under her spell. In addition to being chockfull of healthy protein, “seafood is elegant, clean and light enough to keep your sleek loving machine fully fueled but never weighed down,” says Jacqui Malouf. Oysters are famous- or infamous- for their amorous effects (Cassanova was fond of them) but aren’t for everyone; other romantic dining favorites include shrimp or scallops.
Time to Eat
Once you’ve worked your kitchen magic together, it’s time to move the action into the dining room. Again, a little preparation can keep the evening at a slow, sensuous boil. Use the best china you have, along with matching silverware, cloth napkins and nice glasses (sippy cups don’t count). The warm glow of candlelight can both set off your tantalizing table and set your hearts aflame, along with a rose or two in the most decorative vase you own. Music (from Mozart to Motown, depending on your taste) is another surefire mojo mover. But please guys- catch up with CNN or ESPN some other time.
When you do finally sit down to dinner don’t rush, even (especially) if fast-forward eating is the norm in your house. “Treat the food as if you are making love for the first time,” advises Kerry McCloskey in The Ultimate Sex Diet (True Courage Press). “Before putting any in your mouth, inhale its aroma to get your digestive juices flowing…Cut your food into small, bite-sized pieces, (which) will ensure that you enjoy each bite.” The idea is to enhance all of your senses, which will come in handy later on in the evening.
You can make your couple dining experience even more intimate by feeding each other; some foods. Like asparagus spears and shrimp, beg for finger-feeding. McCloskey recommends also trying chopsticks: “Because it will take longer to maneuver your food when using them, you will feel full sooner with less food.” That’s important since you don’t want to overeat- passing out right after dessert is not the way to impress your partner (they’ve seen you snoring away on the couch a hundred times before).
In the wee hours, happily exhausted, you can ponder this: No matter how hectic your lives get, you should always make time for each other. You already share a mortgage and kids. Cooking together is a great way to share sensuality, too.
June 22, 2005 09:57 PM
Modified Citrus Pectin (MCP)...
June 21, 2005 05:21 PM
By Isaac Eliaz, M.D.
Modified citrus pectin (MCP) is an essential nutrient for cancer prevention and treatment. It directly attacks cancer, thereby reducing the disease, but also has properties that enhance overall health. A true super nutrient! Let me explain how it can do all this.
Characteristics of Cancer Cells
Cancer cells are different from normal cells in a number of ways. One difference is they way they "look." All cells have a variety of molecules on their surface, which allow them to communicate with each other and their environment:
Cancer cells have odd amounts or unusual molecular markers on their surface, which allow white blood cells to recognize the cells as cancerous and kill them. One type of molecule cancer cells have in excess is galectin-3. Galectin-3 molecules function as "hands" and help cancer spread. First, they are important in reaching out and stimulating growth of new blood vessels; this allows the cancer to obtain the blood flow and nutrients it needs to grow out of control. Second, galectins allow cells that break off from the primary tumor to clump together in the blood stream, enabling them to move to new sites. Third, the galectin hand can grab hold of the new location and complete the metastasis, or spread, of the cancer.
MCP Blocks the Spread and Growth of Cancer Cells
Modified citrus pectin is a natural substance that can bind to galectin molecules and block their spread and growth. Early research on prostate cancer showed that oral administration of MCP to rodents resulted in a dramatic reduction in prostate cancer metastasis to the lungs. More recent research by the same scientists extended MCP protection to breast and colon cancer, and showed that MCP blocks primary tumor growth and formation of new blood vessels.
Successful Clinical Trial
A commercially available form of modified citrus pectin was developed in response to the positive animal studies and tested in men with prostate cancer. A pilot trial using MCP at 15 grams a day and a subsequent phase II trial both showed that MCP slows prostate cancer progression, as evidenced by a reduction in the rate of PSA rise. PSA (prostate-specific antigen) is a protein made by the prostate gland; elevated PSA blood levels may indicate prostate cancer. The phase II trial, published in Prostate Cancer and Prostatic Diseases (Dec 2003), involved men who at first experienced successful primary conventional treatment; subsequently their PSA again began to climb, representing cancer recurrence. Seventy percent of these men showed a significant reduction in the rise of their PSA climb! Because of the mechanism of action, it is expected people with other cancers (leukemia, breast, colon, lung, nasopharyngeal, brain, lymphoma, melanoma and others that express galectin molecules) also would benefit from MCP.
MCP Chelates and Removes Toxic Metals
Heavy metals, in conjunction with environmental toxins and xenoestrogens, constitute a dangerous insult to the body through DNA damage, hormonal modulation, immune suppression, oxidative stress, and hyper inflammation. The metal chelation properties of MCP (Eliaz, U.S. patent #6,462,029) have been confirmed in a recent pilot trial. In healthy individuals, MCP increased urinary excretion of the toxic metals mercury, cadmium, arsenic and lead. In addition, longterm administration of MCP has been shown to reduce the body burden of heavy metals such as mercury, arsenic, lead, and nickel. MCP's ability to remove heavy metals and environmental toxins on an ongoing basis may significantly benefit people with cancer and other diseases involving immune dysfunction.
Clinically Validated MCP
Only one form of MCP has been validated in human clinical trials. This is important since no other MCP on the market matches the chemical specifications of the clinically validated product. If the molecular weight of MCP is too high it can't be absorbed into the bloodstream. If it is too low it won't effectively block galectin sites. Another property, the degree of esterification, must be below 5% for optimal binding. The most effective specifications were defined by cell culture studies and remain a trade secret. If you want the effects seen in the clinical studies, you must take the preparation used in those studies, at the recommended dose of 15grams/day.
The Use of Modified Citrus Pectin
MCP Application Use (Take on an empty stomach) Active Cancer 15 grams/day (5 grams, three times a day) Biopsy 15 grams/day (5 grams, three times a day) Take one week before procedure and two weeks after. Heavy Metal Chelation High body burden levels: 15 grams/day (5 grams, three times a day) Lower levels: 15 grams/day for 5 days a month, 5 grams/day the rest of the month Cancer Prevention 5 grams/day ongoing
Pycnogenol Complex - The Next Generation of Antioxidant Protection
June 04, 2005 02:14 PM
If there’s one factor that has the greatest negative impact on our health, it is the damage done to our cells by free radicals. These highly unstable molecules disrupt the biochemical processes that regulate life. Although a natural product of oxygen metabolism in the body, free radicals are also produced in vast quantities by modern technology. Our bodies’ natural defenses simply have not been able to keep up with the onslaught of these dangerous products of civilization. On the other hand, technology has offered help by identifying some of nature’s most powerful weapons against free radical attack. Source Naturals PYCNOGENOL® COMPLEX is an unprecedented combination of these extremely potent plantbased antioxidants, or Plantioxidants™. Consider them your antidote to the industrial revolution.
How free radicals are formed and their effect on the body
Oxygen both makes life, and takes life. The energy that animates us comes from the biochemical reactions that burn oxygen within our cells. And though carefully regulated by the body, this biological combustion, over time, inevitably leads to cellular damage. If oxidation is not carefully controlled, tissues are damaged faster than the body can repair them. This is caused by an excess of over-reactive, electron hungry molecules called oxidants or “free radicals,” which tend to disrupt normal cellular activity. Free radicals attack a cell’s membrane and can even damage its hereditary blueprint (DNA). Since free radicals are a natural result of certain metabolic reactions, the body synthesizes several types of antioxidant enzymes to neutralize them. In addition, we get essential antioxidants from the foods we eat. Vitamins C, E and beta carotene are the ones found most often in our diet. During this century, our environment has become a perpetual source of free radical contamination, primarily from radiation and the chemical pollution in our air, water and food. Today, we are literally overwhelmed with more free radicals than our bodies are accustomed to handling. Fortunately, science has found that certain plants contain special antioxidants that are far more powerful than the vitamins we typically get in our diet. With this knowledge, Source Naturals formulated PYCNOGENOL® COMPLEX, the most advanced combination of Plantioxidants available today in one product. Pycnogenol® is the proprietary name of a natural plant product made from the bark of the European coastal pine, Pinus maritima.
Natural protection against free radicals
Pycnogenol® Complex – A Cornucopia of Health Our knowledge of pine bark goes back nearly 500 years, to when the French explorer, Jacques Cartier, reported that a tea made from pine tree bark by Native Americans saved the lives of his crew who were dying of scurvy. Nutrition scientists have since isolated the extraordinary antioxidant compounds of pine bark. They have also discovered many other unique antioxidants throughout the plant kingdom. Plants have evolved bioflavonoids to protect themselves from free radical damage. One of the most abundant compounds in the plant kingdom, bioflavonoids are found in the pigments of bark, rinds, seeds, leaves and flowers.
Natural antioxidants in Pycnogenol® Complex
The active ingredients of Source Naturals PYCNOGENOL® COMPLEX are derived from a diverse range of nature’s plenty: pine bark, green tea, turmeric spice, rosemary, grape seeds, milk thistle seeds, bilberries, hawthorn berries and ginkgo leaves. Each of these Plantioxidants is an exceptional free radical scavenger, and each has a tendency to concentrate in a different organ of the body, thus providing targeted protection. And since their primary function is to capture free radicals, these Plantioxidants free up vitamin C, so it can perform its many other vital functions.
Defense Plants The two headliners of Source Naturals PYCNOGENOL® COMPLEX are the pine bark extract, Pycnogenol®, and an extract from grape seeds, Proanthodyn™. Their unsurpassed antioxidant activity – up to 20 times that of Vitamin C and up to 50 times that of Vitamin E – comes from a high concentration of proanthocyanidins.
Why Pycnogenol® Complex is formulated with extracts of pine bark and grape seed
These highly bioavailable flavonoids are able to cross the Blood-Brain Barrier, and can stay in the bloodstream for up to 72 hours. Few other nutritional antioxidants cross this barrier, and none do it as well. Proanthocyanidins therefore offer the brain and central nervous system unparalleled antioxidant protection. In particular, proanthocyanidins may help reduce the formation of lipofuscin, a brown waste material made of free radical-damaged proteins and fats. Over time, lipofuscin deposits form in the brain, heart, and skin. The “age” or “liver” spots that develop on the backs of some elderly peoples’ hands are made of lipofuscin. Because they’re rich in unsaturated fatty acids, cell membranes are the primary site of free radical attack. Proanthocyanidins are able to protect against both water- and fat-soluble free radicals. Also, their chemical structure is incorporated within cell membranes, making proanthocyanidins very effective in preventing damage to the cell’s interior. This is vital, because if a cell’s DNA is disrupted, it could lead to the abnormal reproduction of that cell. For many years now, Europeans have used pine bark and grape seed extracts to maintain vein and capillary health. Proanthocyanidins support the circulatory system by helping to keep collagen and elastin, the essential constituents of vessel walls, from breaking down during times of imbalance. And most importantly, proanthocyanidins can help prevent the oxidation of LDL cholesterol in the bloodstream. Scientists now recognize that it’s not cholesterol itself, but the oxidation of cholesterol that can be problematic.
How Plantioxidants benefit different organs in the body
The Power of Diversity
In addition to the broad protection offered by Pycnogenol® and Proanthodyn, Source Naturals PYCNOGENOL® COMPLEX offers an outstanding array of other Plantioxidants. Each has unique abilities to protect the body from oxidants. For several thousand years, Green Tea has been enjoyed in the Orient, not only for its taste, but also as a health tonic. Upon analysis, it contains several strong antioxidants, called Polyphenols, with exceptional free radical scavenging abilities. Polyphenols have been shown to be over 200 times more effective than vitamin E in preventing oxidative damage to brain cells. Source Naturals uses a potent extract of green tea that concentrates 2,000 pounds of fresh green tea leaves into one pound of finished product. This extract has been awarded 30 patents for its protective effects. The ancient Ginkgo Biloba tree has long been prized for its beneficial qualities. Like proanthocyanidins, ginkgo’s compounds are able to cross the Blood-Brain Barrier, and support cell membrane and capillary integrity. Its particular antioxidant constituents have been associated with superior oxygen transport to the brain. This is important because the brain uses 20% of all inhaled oxygen. Source Naturals PYCNOGENOL® COMPLEX uses a superior 50 to 1 extract, providing 24% Ginkgoflavoneglycosides and 6% Terpenoids. Bilberries were first studied for their capacity to heighten visual acuity in normal subjects under poor light conditions. In fact, to increase their night vision, RAF pilots ate bilberry jam during WW II. Its antioxidant compounds, Anthocyanosides, have an affinity for delicate eye tissues, where it quenches free radicals and supports capillary strength. Source Naturals utilizes a standardized bilberry extract with 25% anthocyanosides, 80 times more potent than regular bilberry.
The wide range of natural antioxidants in Source Naturals PYCNOGENOL® COMPLEX
Milk Thistle Seed Extract has been researched and used for over 20 years in Europe. Its antioxidant compound, called Silymarin, has a special preference for the liver. It’s one of the few nutrients that can support the liver’s natural regenerative processes. By enhancing DNA activity, liver cells can regenerate up to five times faster. Turmeric Extract contains 95% Curcumin, the active ingredient of this traditional East Indian spice. Curcumin promotes the body’s own production of antioxidant enzymes, including glutathione peroxidase, an important protector of the liver. Curcumin also increases the production and secretion of bile, which is used to remove cholesterol from the body. Quercetin has been well-researched for its free radical scavenging activity. Because of its ability to stabilize cell membranes, quercetin helps prevent damage and discomfort from reactionary (histamine- and leukotriene-related) processes in the body. Source Naturals quercetin has been isolated from plant sources. Rosemary and Hawthorn Berries both contain bioflavonoid antioxidants that have the unique ability to neutralize the hydroxyl radical, a particularly dangerous type of free radical. Hydroxyls are produced by exposure to excessive radiation and pollution from burned fossil fuels. The body has no innate defense system against it. Vitamin C is one of the most active and abundant antioxidants in the body, so it must be frequently replenished. Since it works in conjunction with bioflavonoids, each tablet of Source Naturals PYCNOGENOL® COMPLEX contains 500 mg of vitamin C, bound to Magnesium for increased bioavailability.
A World of Help
As we better understand how free radicals affect our health and well being, it’s important that we take advantage of the wonderful protective qualities found in certain plants. These Plantioxidants provide the appropriate means to counteract the destructive effects of excessive free radicals, which have become part and parcel of modern life. Source Naturals PYCNOGENOL® COMPLEX brings the diverse and concentrated power of the plant world into your world of wellness.