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Ginkgo biloba shows potential value in the treatment of over 100diseases Darrell Miller 3/7/19
Compelling study confirms the therapeutic effects of curcumin inremoving fluoride from our bodies Darrell Miller 12/3/18
Is Your Flaxseed Rancid? Darrell Miller 3/17/17
The Dangers of Vegetable Oil Darrell Miller 7/21/15
WHAT YOU DIDN'T KNOW ABOUT COCONUT OIL Darrell Miller 2/6/14
Fight Free Radical Damage From Toxins With Vitamins And Herbs Darrell Miller 7/28/10
Coconut Oil Darrell Miller 8/18/08
Calcium D Glucarate Darrell Miller 7/25/08
Multiple Vitamins Darrell Miller 6/11/08
For Better Heart Health ... Darrell Miller 2/6/07
Selecting Quality Evening Primrose Oil Darrell Miller 6/3/06
WHAT IS A FREE RADICAL? Darrell Miller 7/13/05
<B>DO WE NEED EXTRA LIVER PROTECTION?</b> Darrell Miller 7/12/05
HAWAIIAN NONI (Morinda citrifolia) Darrell Miller 7/11/05
GARLIC AS AN ANTIOXIDANT Darrell Miller 6/25/05
Fats for Life - the quality of the fat you eat is probably much more important than the... Darrell Miller 6/12/05
Neptune Krill Oil (NKO) - for Healthy Heart, Joints, and other Body systems Darrell Miller 6/3/05
Heart Science - A Five-Tiered Approach to Heart Health ... Darrell Miller 6/2/05
Cholestrex - Lower Cholesterol with Source Naturals Supplements Darrell Miller 6/1/05
Re: Acetyl-L-Carnitine - Anti-Aging Brain Nutrient ... Darrell Miller 5/31/05




Ginkgo biloba shows potential value in the treatment of over 100diseases
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Date: March 07, 2019 09:23 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Ginkgo biloba shows potential value in the treatment of over 100diseases





If you want to protect yourself against more than 100 different common diseases, there is one herb that should be a part of your daily life and that is Ginkgo Biloba. Studies have been conducted and the results prove that it is worth your time and effort in more ways than one because it has the ability to ward off migraines, ADD, and dozens upon dozens of other conditions that affect so many people today.

Key Takeaways:

  • The gingko biloba tree is called a “living fossil” due to the fact that it has no close living relatives and can be traced to the dinosaur age.
  • The gingko biloba tree can be used for longevity because the tree can live for up to 1,000 years and also, it can be used to treat Alzheimer’s disease.
  • An analysis of the tree extract using 21 trials found that the tree can help those with mild cognitive impairment to improve their thinking.

"The ginkgo biloba tree might not give off the most pleasant smell, but hiding beneath its rancid odor is the power to heal more than 100 different diseases."

Read more: https://www.naturalnews.com/2019-01-23-ginkgo-biloba-shows-potential-treatment-of-over-100-diseases.html

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Compelling study confirms the therapeutic effects of curcumin inremoving fluoride from our bodies
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Date: December 03, 2018 02:03 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Compelling study confirms the therapeutic effects of curcumin inremoving fluoride from our bodies





According to statistics recently released by the CDC, 66.3% of U.S. citizens are being exposed to fluoride poisoning through the country's public water supplies. The good news is that a study in Pharmacognosy Magazine points to curcumin as a natural solution to this growing problem. According to this Indian study, curcumin can protect our brains from fluoride poisoning. If you cannot afford to install a whole-house water filter in your home, curcumin may be a safe and affordable option to protect your family from the dangerous neurological effects of fluoride.

Key Takeaways:

  • In our bodies, there are so many chemicals that have to work together at any given time.
  • The public water in the United States is causing a large number of people to have fluoride issues.
  • The bottom line is that fluoride chemicals should have no presence in the water that people drink.

"The researchers looked specifically at fluoride-induced toxicity on the mice’s brains, including the chemical’s impact on lipid peroxidation, or rancidity, in brain tissue. They also evaluated markers of malondialdehyde, or MDA, a well-known marker of oxidative stress and oxidative damage, in the brains of mice from each test group."

Read more: https://www.naturalnews.com/2018-11-26-curcumin-removing-fluoride-from-the-body.html

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Is Your Flaxseed Rancid?
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Date: March 17, 2017 06:44 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Is Your Flaxseed rancid?





A couple of years ago, all things flax (flax seeds, ground flax, and flaxseed oil) became very popular. And with good reason; the little seeds contain a wealth of omega-3 and omega-6 fatty acids. However, what few people know is that once flax goes rancid, it degrades the health profile and alters the taste, aroma, and appearance of the seeds and oil. In fact, flax is sensitive to heat (it starts breaking down at 225 degrees Fahrenheit) and starts oxidizing if it’s exposed to light after only a few hours.

Key Takeaways:

  • A couple of years ago, all things flax (flax seeds, ground flax, and flaxseed oil) became very popular.
  • The little seeds contain a wealth of omega-3 and omega-6 fatty acids.
  • However, what few people know is that once flax goes rancid, it degrades the health profile and alters the taste, aroma, and appearance of the seeds and oil.

"However, what few people know is that once flax goes rancid, it degrades the health profile and alters the taste, aroma, and appearance of the seeds and oil."



Reference:

//www.healthnutnews.com/is-your-flaxseed-rancid/

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The Dangers of Vegetable Oil
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Date: July 21, 2015 05:23 AM
Author: Darrell Miller
Subject: The Dangers of Vegetable Oil

More often than not, when we see the words vegetable oil, we assume that it is good for us since vegetables are essentially beneficial for the body. The truth of the matter is that this kind of oil is mostly derived from seeds such as sunflower, soybean and corn, not from any kind of vegetable at all. Aside from this, their extraction requires a process that uses up a lot of energy and is not good for the environment.

Vegetable Oil

Trans Fats

Unsaturated fats, otherwise known as trans fats, are fats that are usually solid at room temperature but processed in such a way that they are not when they come in the form of oils derived from seeds. These contribute to diabetes, heart disease, cancer and obesity. The sad part is that although there are so many calls to action regarding minimizing the presence of trans fats in food; there is very little that has been done regarding their presence in vegetable oils. How trans fats were developed or discovered will show how scary it actually is. It was discovered while looking for an alternative to tallow which is an ingredient for candle wax. It was cheap and convenient to harness and use. The reason why it is widely used is because of its extended shelf life. It can also be reused several dozen times for frying without changing flavor or adding a rancid taste to the food fried in it.

Mutated Fats

The process of extracting the oils from their sources requires a lot of heating and, for some, even exposure to acids and metals which contribute to the "mutation" that these oils undergo. Hydrogenated vegetable oil confuses our bodies into thinking that they are good for us. This is mainly due to the processes that changes their form. HVO alters the structure of our cells, making them weak and lowering the good cholesterol as well as raising the bad. Our bodies welcome these fats and do not treat them as a danger although their presence does, in fact, increase the risk of heart disease, diabetes and other diseases.

Imbalances

Vegetable oils can also cause imbalances in the composition of our fatty acids. Omega 3 and omega 6 fatty acids are not produced by our bodies. Therefore, we need to supplement these from our diets and daily consumption in pretty much the same amounts to balance their presence in the body. Polyunsaturated fats from HVO that causes the mutation in our cell membranes can lead to oxidative chain reactions which are harmful to our cells. In essence, our cells are made weak and the chances of alterations to our DNA are increased. Omega 6 is abundant in HVO because it helps to slow the deterioration of the vegetable oil. It can cause an imbalance to the cell membrane causing inflammation in various parts of the body. One component of Omega 6 that is highly dangerous is linoleic acid. It has been linked to obesity, high levels of bad cholesterol and even damage to the brain's hypothalamus.

These are just a few of the dangers that come with using so called vegetable oils. These dangers are kept under wraps because of the massive income that the food industry will lose if it changes the oils used for cooking and preparing food.


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WHAT YOU DIDN'T KNOW ABOUT COCONUT OIL
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Date: February 06, 2014 07:56 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: WHAT YOU DIDN'T KNOW ABOUT COCONUT OIL

Introduction to coconut oil

coconut oilCoconuts have come under close scrutiny by health experts and enthusiasts alike. The popular nut that is favored by the climates at the tropics is slowly cementing its place in household shelves worldwide. The white fleshy part has given us a healthy oil with a diverse resourcefulness.

Benefits of Coconut oil

Coconut oil's reputation had been blemished by inconclusive studies that had suggested that due to its 90 percent concentration of saturated fats, it couldn't pass for a healthy oil. High saturated fat content is usually associated with artery clogs and this, in the case of coconut couldn't be any further from the truth. Coconut oil is arguable the richest source of saturated fat. Contrary to popular belief, during digestion, the fatty acids in the oil are sent to the liver where they are converted to energy or into ketone bodies that help counter brain disorders such as Alzheimer's.

Coconut oil has also wound its way to the breakfast table as a spread. It beats butter hands down as the healthy alternative when taken on toast.

It adds a remarkable nutty flavor to your food when used as a cooking fat. The fact that it does not exhibit any signs of rancidity under high temperatures as most cooking oils do, only underpins its reliability. Whether you use it to fry an egg or make a fuller meal, the health benefits it brings to the table are unparalleled.

Coconut oil has also crept into the snack world. Movie theatres have pioneered this trade by using it to prepare popcorn. Australian snack producers have also incorporated it into some of their beloved treats such as chocolate crackers. Bakers are opting for it as they also caught in this healthy food revolution.

We have also seen coconut oil used in massages, as an anti-dandruff and also as skin moisturizer.

The comprehensiveness of this oil makes it the ultimate everyday supplement to you as an individual and even your home.

Source

1. //www.swansonvitamins.com/blog/natural-health-tips/using-coconut-oil
2. //wellnessmama.com/2072/benefits-of-coconut-oil/
3. //en.wikipedia.org/wiki/Coconut_oil
4. //authoritynutrition.com/top-10-evidence-based-health-benefits-of-coconut-oil/



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Fight Free Radical Damage From Toxins With Vitamins And Herbs
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Date: July 28, 2010 11:34 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Fight Free Radical Damage From Toxins With Vitamins And Herbs

There are many things that destroy the immune system. Each day we are bombarded with them in many forms. The following are some of the most common ones that are encountered.

Agene, also known as Nitrogen Trichloride, is used to bleach flour and give it a white appearance. Unfortunately, it can cause epileptic-like fits along with failure of muscle coordination. Excessive use of alcohol also severely impairs the immune system. It increases susceptibility to infection and weakens the central nervous system. Alcohol promotes chronic lung disease, malignancies of the neck and head, intestinal problems, hypoglycemia, diabetes, liver disease, and a whole variety of other problems. B vitamins, folic acid, niacin, vitamin E, magnesium, zinc, and protein are depleted by alcohol. All of these nutrients play a huge role in immune health. Aspartame breaks down in the digestive tract into a toxic material known as methanol. In order to prevent methanol from metabolizing into formaldehyde, a poison, a person needs to take another poison, ethanol.

Glutamic acid is a substance that is found in monosodium glutamate, a flavor enhancer. It affects the central nervous system and can trigger depression, gloomy fantasies, and rage for as long as two weeks following the ingestion of monosodium glutamate. High-diet fat intake increases the levels of bile acids in the colon. This breaks down into deoxycholic and lithocholic acids, both of which are cancer-causing elements. This can cause cancer of both the colon and the rectum. A diet that is high in animal protein and fat can cause cancer of the pancreas, breast, gallbladder, ovaries, uterus, prostate, and leukemia. Junk food such as sweets, white flour, and white sugar products, put a double amount of stress on the body. When too much junk food is eaten, the appetite for good, wholesome food is dulled.

Caffeine decreases immunity in the body, with fibrocystic breast disease being connected with the consumption of foods that contain caffeine. It is often caused by the chemicals methylxanthine, theophylline, and theobromine, which are found in coffee, black tea, cola drinks, chocolate, and other soft drinks. These elements act on hormones that cause breast tissue to develop fibrocystic lumps. Caffeine takes away the body’s own use of iron and inositol, and is often suspected of causing cancer in the pancreas.

Food dyes and flavorings are the culprits in behavioral problems that occur in children and adults, with some of these problems being learning disabilities and hyperactivity. Sodium nitrate is a preservative that is often found in cured meats like hot dogs, bologna, and ham. It has the potential to produce permanent epileptic changes in brain activity and damage the central nervous system.

High protein diets can deplete calcium in the body, especially when the source of protein is an animal product. There are concentrated doses of hormones and antibiotics that are found in beef which suppress the immune system and promote tumor growth. Poly-unsaturated fats undergo a process that produces rancidity in oils. This process releases dangerous free radicals, which eventually lead to cancer.

Heavy metals like lead and mercury can cause serious damage to the nervous system, with even small amounts being considered toxic. Lastly, the wide use of vaccinations and antibiotics is considered to be one of the main causes of immune system disorders.

Our bodies are under constant attack by our toxic environment. Fortunately, with regular vitamin and herb use, one can help the body restore its immune system to proper function so we can live a happier healthier life.

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Coconut Oil
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Date: August 18, 2008 12:01 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Coconut Oil

Whether coconut oil is good for weight loss or not, it is becoming an increasingly popular component of a weight loss diet. So how justified is this in view the fact that fats and oils are not normally regarded as being the best form of food to take if you want to lose weight?

Apart from any other considerations, fats are actually very important components of any diet. Consider, for example, how many vitamins are fat soluble: vitamins A, D, E and K are all fat soluble, and without fats in your diet vitamins would not be able to circulate and be taken to where they do most good. Fats are also essential building blocks for hormones and cell membranes. In short, you cannot survive without fats. Coconut oil is a fat.

In referring to coconut oil here, we are discussing virgin oil, not the refined form that is high in cholesterol. Refined, or processed coconut oils, is hydrogenated, which renders it more in nature to the longer chain fatty acids. Virgin coconut oil contains what are known as medium chain fatty acids (MCFA), which are easily metabolized by your liver into energy.

The longer chain fatty acids, also called triglycerides, are not easily broken down into smaller components, and tend to be stored in the body as fat. This fat can be particularly dangerous if stored round the midriff, and so long chain fatty acids are dangerous to your health. This does not apply to MCFAs, and a possible mechanism for this is discussed later.

An inability to distinguish between the different types of fats and oils in your diet is largely due to a lack of education in the chemistry of fats, and the lumping together of all fats and oils under the 'fatty' flag. Perhaps it is the use of the word 'fat' for the overweight condition and the fact that the triglycerides and other chemicals are known generically as 'fats' that triggers a connection between the two, but although this is logical, and in some cases justified, it is not always the case. There are fats and fats, just as there are lubricating oils and greases, and edible cooking oils and greases.

The fatty acids in coconut oil are composed of relative small carbon chain lengths. Caprylic acid and capric acid contain 8 and 10 carbon atoms in the backbone compared to the 18 of the stearic acid that is commonly contained in animal fats. The longer the carbon chain in the molecule, the more difficult it is to break down, and the more likely it is to be stored in the body as a dense fatty deposit that places a strain on the heart.

Due to the shorter chain length the medium chain fatty acids hold less energy per unit weight. Apart from any other reasons then, coconut oil contains fewer calories than other fats and so if used as the bulk of your fat requirement, will be less liable to generate body fat. Not only that, but as inferred earlier, due to the smaller molecule these calories are more readily released as energy for use by your body rather than stored unused.

However, that is not the whole story on either count: coconut contains saturated fats, and also monounsaturated and polyunsaturated fats, although in small quantities. These, however, are present in only small amounts, although would still be expected to undergo oxidation and produce the rancid taste commonly found in aged unsaturated oils and fats. However, even after a year this does not happen, which indicates that coconut oil possesses some form of antioxidant properties. This is confirmed by the fact that people eating a diet rich in coconut oil has less of a need for the strong oil-soluble antioxidant vitamin E.

In fact, the metabolism of fats is usually connected with the carnitine transport system in the mitochondria, although the shorter chain fatty acids do not need carnitine for their metabolism. What happens then is that because carnitine promotes oxidation during stress, and causes oxidative damage to body cells, its absence in metabolism of coconut oil fatty acids results in a reduction in the oxidation that degrades unsaturated fats. Hence the lack of rancidity.

Taking this further, then, this lack of oxidation infers that those that take a diet rich in coconut oil (for example using it for cooking rather than animal and vegetable oils containing longer chain fatty acids) should be partially protected against cell oxidation in general. Oxidative effects such as aging, cardiovascular diseases and some cancers should be reduced, and studies have shown this to be the case. Those consuming coconut oil rather than other oils tend to age more slowly, suffer less from heart disease and tend to experience fewer incidences of cancer.

With regard specifically to weight loss, it is believed that consumption of medium chain triglycerides, as opposed to longer chain triglycerides, results in a higher rate of thermogenesis, or the conversion of carbohydrates to energy (fats are also carbohydrates). The first step in this process requires the presence of Coenzyme A in the form of the enzyme acyl-CoA-dehydrogenase, and measurement of the activity of this enzyme has indicated that medium chain triglycerides exhibit much higher expenditure of energy than the metabolism of long chain triglycerides when being converted to fatty tissue. However, though the energy used up in this reaction, known as lipogenesis, was higher, the formation of fatty tissue was the same.

Hence, MCA uses more energy to produce the same amount of fat as LCA, and therefore, although more energy is used up, no new fat is generated by the liver. Since your dietary fat intake can ultimately have only three fates: burned as energy, stored as the emergency energy source glycogen, or deposited as fat, then it is logical that the more energy generated then the less fat will be stored.

In this way, coconut oil, with a high content of medium chain fatty acids, has a scientific explanation for causing weight reduction when used as a source of fat in the diet rather than animal or other vegetable fats or oils. It is converted to energy rather than fatty tissue, and if you exercise to use up that energy then your weight loss can be significant.

What this theory also states, however, is that coconut oil should be used as a replacement for other fats, and not in addition to it. If you take coconut oil in addition to your normal diet, do not expect to see results.

--
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Calcium D Glucarate
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Date: July 25, 2008 10:57 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Calcium D Glucarate

Studies have found that D-glucarate has therapeutic actions; among these are cancer prevention and serum cholesterol reduction. However, its most impressive property could be its ability to quickly detoxify the body of both artificial and natural toxins which can be potentially harmful. These toxins can be neutralized in many ways, with glucuronidation being one those ways. The process of glucuronidation involves using the liver to neutralize chemical carcinogens and steroidal hormones including estrogen. Once a toxin has been glucuronidated in the liver, it goes to the bile and is eventually eliminated from the body in the stool.

Beta-glucuronidase is an enzyme that is produced in the gut by unfriendly bacteria which can actually inhibit this process by chemically splitting a glucuronidated toxin before it is able to be eliminated in the stool. This unbound toxin can come into contact with the bowel lining where it can be reabsorbed and the whole process will be repeated. When a situation like this happens, cells are exposed, once again, to the chemical and the liver can become overworked. Thankfully, if D-glucarate is present, beta-glucuronidase is inhibited, resulting in a flawless glucuronidation in the body.

These findings suggest that taking D-glucarate orally as a supplement can provide us with the increased ability to efficiently and rapidly rid our bodies of toxins through problem-free glucuronidation. Additionally, D-glucarate does not work like an antioxidant, which neutralizes free radicals, but instead actually forms a type of bond with harmful compounds to enhance their rapid removal from the body. Some of the organs that can be especially toxin-sensitive are the breast, prostate, liver, lung, and kidney, therefore, they can greatly benefit from this process. These organs can be most damaged by the continued exposure to poisons and carcinogens.

Because our generation, more than that of any other, is exposure to a great number of potentially harmful environmental pollutants, our contact with carcinogens increased exponentially. Just some of the cancer-causing agents include cigarette smoke, pesticides, radon, hormonally-fattened meats, diagnostic and therapeutic x-rays, gamma radiation, trans-fatty acids, alcohol, poor diets, xeno-estrogen, herbicides, smog, car exhaust, certain prescription drugs, ultra-violet light, rancid foods, saturated / hydrogenated fats, some food/water supplies, and food preservatives. Although a lot of us have taken necessary measures to protect ourselves from exposure to the substances listed, it is inevitable that we will consistently take chemicals that can prompt the growth of cancer into our bodies.

Additionally, our own hormones can be a threat if they are not efficiently metabolized and excreted from our body. One study found that Glucarate supplementation amplifies the process by which carcinogens and hormones are removed from the body, while D-glucarate can exert a positive effect on different stages of the carcinogenic process. It has been found that lower cancer rates in some populations could be attributed to their consumptions of foods that are rich in D-glucaric acid, self-medicated with D-glucarate, or combine D-glucarate supplementation with other chemopreventive agents.

Either way, the protective function of glucarate in the body’s natural cancer prevention mechanisms has been established for long periods of time, while other recent studies have indicated that the use of glucarate could potentially present a fifty percent decrease in tumor incidence.

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Multiple Vitamins
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Date: June 11, 2008 04:51 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Multiple Vitamins

Multiple vitamins should be designed with one purpose in mind. They should provide you the ability to properly balance your regular diet with the additional vitamins, minerals, amino acids and antioxidants needed to make your diet nutritionally complete.

It is rare that people follow the recommended daily allowances in their regular diets. For this reason, multi-vitamins were developed to provide the missing nutrients to your daily diet. Vitamins designed with this purpose will automatically provide you with the essential additional nutrition you need to boost your health and wellness.

The Correct Multi-vitamin Make-Up:

A good multivitamin supplement will contain all of the following ingredients. It is designed to balance an average diet and boost health and wellness.

* Major vitamins * Minerals * Amino acids * Carotenoids * Tocopherols * Tocotrienols * Antioxidants

Antioxidants are an important part of any diet because they attack and neutralize free radicals. These fragments of chemicals are caused by:

* Normal metabolism * Pollution * Ultraviolet radiation * rancid oil * Other toxins

Scientists believe that free radicals are one of the elements responsible for aging and degenerative diseases like Alzheimer's, arthritis and cancer. It is because of the nutrient deficiencies in our regular diets that we have become more susceptible to degenerative diseases.

Mixed Tocopherols and Tocotrienols:

Vitamin E is a series of related compounds. The four main forms are alpha, beta, delta and gamma. Most multi-vitamin supplements only contain large amounts of alpha tocopherol. A healthy diet needs a mixture of them all.

When too much alpha tocopherol is induced, gamma tocopherol is depleted. This causes deficiencies because gamma tocopherol is crucial to good health as well. For this reason, it is important that your tocopherol intake is balanced. A mixed intake of all tocopherols is more effective in preventing cardiovascular disease.

Tocotrienols are potent antioxidants that complement the alpha tocopherol. The combined nutrients are much more effective at preventing oxidation. This is why you must have a balanced combination of tocopherols and tocotrienols to maintain a healthy diet and a healthy body. To accomplish this you must have a balance of all of the compounds that make up vitamin E.

Mixed Carotenoids:

These are the red, orange and yellow plant pigments that are found in all of our fruits and vegetables. All of these contain different amounts of carotenoids, but the colors are often hidden by the plant's chlorophyll content. Examples of foods containing large amounts of carotenoids include:

* Kale * Collard greens * Swiss chard * Broccoli

Tomatoes contain Lycopene, which is a red carotenoid found in tomatoes. It is a potent antioxidant that reduces the risk of prostate cancer. Unfortunately, carotenoids are better absorbed through the ingestion of supplements than from foods. Multi-vitamins usually only contain beta carotene. It is important to find one that contains beta carotene, alpha carotene, lycopene, lutein and zeaxanthin.

The Bottom Line:

A complete multiple vitamin supplement is necessary as a part of a daily health and wellness regimen. The best multi-vitamin contains a healthy balance of everything listed above in the correct dosages. It is important to do your homework and be sure the multi-vitamin you choose will do its job correctly.

Learn as much as you can about your own body's individual nutritional needs. By giving your body proper nutrition, you help it to fight off illness and diseases much more efficiently. A complete multi-vitamin will:

* Strengthen your immune system * Decrease your risk of cancer, heart disease and osteoporosis * Increase your level of energy * Elevate your moods * Help you to enjoy a healthier, more productive life

Choose a multi-vitamin that has been developed based on the latest science and technology. You will be taking a well-rounded supplement that was designed to properly complement a typical daily diet.



--
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For Better Heart Health ...
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Date: February 06, 2007 12:57 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: For Better Heart Health ...

Nutrients Every Heart Needs

 

High blood pressure. High cholesterol levels. Ever increasing stress. All are factors related to the development of heart disease – the leading cause of death for both men and women. In fact, 1 in 2 women in the United States die of heart disease or stroke, while 1 in 30 dies of breast cancer. If current trends remain unchanged, not only will heart disease remain the primary killer in our country, the number of people it claims will steadily and dramatically increase in the next 20 years.

 

Fortunately, heart disease is a problem you can do something about. Proven ways to prevent or mitigate the effects of heart disease include taking targeted nutritional supplements, making changes in the foods we eat, exercising most days of the week, drinking in moderation, eliminating tobacco use and adapting a positive attitude. Research shows that those of us who are often angry and depressed have more heart disease than people that live their lives with a more positive outlook.

 

In this Ask the Doctor, we’ll talk about specific nutritional supplements that are heart healthy, whether your goal is to prevent heart disease or reduce the effects of heart disease if you currently have it.

 

Q. I am trying hard to live a healthier life. But it all seems so overwhelming. How do I start?

A. It may help to know that you’re not alone in feeling overwhelmed. Lots of people feel this way. This is why the Centers for Disease Control and the American Heart Association are both urging people to prevent heart disease by identifying their individual health risk factors.

 

A risk factor is an indicator of whether or not you may develop a certain health condition. In heart disease prevention, there are two kinds of risk factors. There are risk factor you can control – such as diet, exercise, and the supplements you take. There are also risk factors you can’t change or control –your age, race, and gender, as well as your family’s history of heart disease.

 

Examples can be really helpful. Let’s follow three adults – Fred, Jane, and Earl – and determine their risk factors.

 

Low Risk

Fred is 32, single, has a job he loves, has an optimistic attitude about his life, and works out 5 days a week. Most days Fred’s diet is fruits, vegetables, whole grains and low fat. Occasionally Fred will eat a cheeseburger and fries when he watches the game with his buddies. Fred’s risk factors are his male gender and the occasional high fat content in his diet.

 

Moderate Risk

Jane is 55, a lawyer, married, and has a very stressful job. Jane eats lots of salads, fruits, and whole grains. However, her job requires her to work long hours which leaves little time to exercise. Jane is for the most part happy with her life, but her work stress had led to times of negativity. Her father had a heart attack when he was 56. Jane’s risk factors include her age (greater than 50), negativity from job stress, lack of regular exercise, and a family history of heart disease.

 

High Risk

Earl is 65, married, and has just retired from a job he hated. He spends most of his day watching TV and eating potato chips and other high fat, salty snacks. Earl has told his friends and family since he worked so hard for so long, he is sure to drop dead soon after retiring. He has high cholesterol and high blood pressure. Earl’s father had a heart attack and died when he was 73. Earl’s risk is his male gender, age (greater than 50), sedentary lifestyle, poor diet, negative outlook on life, high cholesterol and high blood pressure, and a family history of heart disease.

 

Q. OK, it’s pretty easy to see that Fred needs to watch his diet, Jane needs to exercise more, and Earl needs lots of help. But, which supplements should they take?

A. The Whole Heart Nutrition chart is an easy way to determine the supplements each risk level needs. As you can see, everyone wanting to prevent heart disease – Fred, Jane, Earl, you, and I – need to take quality heart formula multivitamin, garlic, and a fish oil supplement providing Omega-3 fatty acids. CoQ10 is also a smart choice for complete heart heath support.

 

Q. Why do we all need to take a “heart multivitamin”? Why can’t we take a regular multivitamin to prevent heart disease?

A. Since the human heart simply cannot function without adequate amounts of certain vitamins and minerals, it seems logical that a multivitamin would be the foundation of good nutrition for your heart. Heart-health formulated multivitamins provide the exact nutrients needed to prevent heart disease.

 

That’s why we need to take a specially formulated heart-focused multi-vitamin. The cells and the tissues that make up the heart must have vitamins C, A, and E, as well as B1, B6, and B12 to function. Folic acid, the little B vitamin that is so crucial in preventing spina bifida (a birth defect), breast cancer, and Alzheimer’s disease is also needed to keep heart muscles strong. The B vitamins and folic acid are very important to heart health because they help lower homocysteine levels. Homocysteine is a potential and emerging cardiac risk factor,

 

Magnesium is a mighty mineral and healthy hearts need it every day. Aloha lipoic acid, a fatty acid, provides protection against heart cholesterol and high blood pressure. Lutein and lycopene are all-natural nutrients and keep our arteries free from the buildup of plaque, a condition linked to heart attacks and strokes.

 

Multivitamins formulated with these exact vitamins, minerals, and nutrients will work with medications often prescribed to treat heart disease and provide the nutrition our hearts need.

 

Q. Don’t all multivitamins work with medications prescribed to treat heart disease?

A. Many multivitamin formulas contain herbs and other nutrients that can interfere with prescription medications, especially mediations prescribed to treat heart disease. One multivitamin does not fit all.

The more risk factors you have, the greater your chance of developing heart disease.

Factors you CAN’T change

 

Increasing age

About four out of five people who die of coronary heart disease are 65 or older.

Male gender

Men have more heart attacks than women. Even after menopause, when women’s death rate from heart disease increases, men continue to have more heart attacks until both groups reach their 80s.

Heredity (including Race)

While heart disease has often been noted to occur in families, recent research has shown this link may be the result of environment more than heredity. In other words, your dad’s high blood pressure and your high blood pressure may be related more to your mutual love of salty foods than your genetics. African Americans tend to have very high blood pressure and a higher risk of heart attacks than other races.

Factors you CAN change

 

Tobacco smoke

Smokers have twice the risk of heart attack than nonsmokers.

High blood cholesterol

As blood cholesterol rises, so does the risk of heart disease.

High blood pressure

High blood pressure increases the heart’s workload, causing the heart to thicken and become stiffer.

Physical inactivity

Exercise most days of the week helps prevent heart disease. The more vigorous the activity, the greater your benefits.

Obesity and overweight

People who have excess body fat are more likely to develop heart disease and stroke even if they have no other risk factors.

Individual coping styles

Research has shown there is al ink between heart disease risk and stress, happiness, negativity, and socioeconomic status.

Alcohol consumption

Drinking too much alcohol can raise blood pressure. However, the risk of heart disease in people who drink moderate amounts of alcohol (an average of one drink for women or two drinks for men per day) is lower than in nondrinkers.

 

Q. What can garlic supplements do for Fred, Jane and Earl or other people with low to high risk factors?

A. Garlic supplements have a very long and very successful history of preventing premature death from heart attacks. Lately, however, there have been some conflicting news stories about supplemental garlic’s ability to lower high cholesterol and high blood pressure – the causes of heart disease and death. That’s because many different garlic supplements have been used in these studies – garlic oil, garlic powder, aged garlic extract, and supplements made from fresh garlic. They have all been studied clinically for their effects in heart disease.

 

The best garlic supplements (and the ones that showed the best effects in garlic studies) contain alliin, which is then converted to allicin. Allicin is the compound that lowers harmfully high cholesterol levels and dangerous blood pressure readings. Allicin is also responsible for garlic’s characteristic odor. Because alliin is very stable when dry, properly prepared and enteric coated fresh garlic preparations preserve the allicin-producing action until the garlic mixes with the fluids of the intestinal tract. Fresh garlic extract’s enteric coating also prevents garlic breath. In contrast, aged garlic contains absolutely no allicin or allicin potential. This fact is probably responsible for the poor results noted in lowering cholesterol and blood pressure from aged garlic preparations.

 

The most effective garlic supplements are made from fresh garlic, enteric coated, and provide a daily dose of at least 10 milligrams (mg) alliin or a total allicin potential of 4,000 micrograms (mcg). Taking a once-daily garlic supplement that delivers 4,000 mcg of allicin will lower Jane’s and Earl’s high blood pressure and Earl’s high cholesterol, naturally and effectively.

 

Whole Heart Nutrition

Supplement

Low Risk

Moderate Risk

High Risk

Heart multivitamin

Every day

Every day

Every day

Garlic supplement 4,000 mcg allicin

1 tablet each day

1 tablet each day

1 tablet each day

Fish oil supplement with omega-3 fatty acids

600 mg each day

1200 mg each day

1800 mg each day

CoQ10

60 mg

100-200 mg each day

200-400 mg each day

Each additional risk factor requires additional supplements or increased doses for protection from heart disease.

 

Q. What about fish oil supplements? I know they can prevent heart disease but I’ve also heard they contain harmful substances, too.

A. You’re right on both counts. But, there are excellent fish oil supplements naturally loaded with Omega-3 fatty acids, powerful nutrients that prevent heart disease, that are also certified free of harmful contaminants.

 

In the 1980s, researchers first began noticing the native Inuit (Eskimo) populations of Greenland and Alaska had hardly and heart disease despite a very high-fat diet. The deep-water fish that these peoples eat (and continue to eat to this day) are indeed quite fatty. But, this kind of fat, rich in Omega-3 fatty acids actually protects the heart instead of harming it.

 

Research has shown that the Omega-3 fatty acids in fish oil supplements can:

-Reduce the risk of arrhythmias, lethal heartbeat rhythms that cause sudden death.

-Lower the levels of triglycerides, fats in the blood that can increase a person’s

risk of dying from a heart attack, even if a person’s cholesterol levels are normal.

-Slow atherosclerosis – the growth of harmful plaque on artery walls.

Atherosclerosis develops over many years. If the plaque growth is slow and

stable, chances are low that a heart attack will result. However, rapidly growing

or unstable plaques can rupture. The body responds with inflammation, which

causes blood clots to form. These blood clots block the artery and cause a heart

attack.

-Keep blood pressure levels low. Many people have high blood pressure for years

without knowing it. That’s because it has no symptoms. Uncontrolled high

blood pressure can lead to stroke, heart attack, heart failure, and kidney failure.

While 25% of Americans have high blood pressure, nearly one-third of these

people don’t know they have it. This is why high blood pressure is often called

the “silent killer.”

 

You can get all of this heart disease preventive protection from just 600-1800 mg of fish oil. It’s pretty simple to see why Fred, Jane, Earl, and you and I need to take fish oil supplements every day.

 

However, it is absolutely critical that the fish oil supplement you take is free of contaminants and guaranteed fresh! Make sure that the manufacturer of the fish oil supplement you buy is able to provide documentation of purity in their product. Supplements should contain no detectable dioxin (a widely used toxic preservative), DDT (a toxic insecticide), PCBs (polychlorinated biphenyls) or heavy metals such as mercury and lead.

 

Before you buy any fish oil supplement, ask the clerk if you can open the bottle or jar and smell the contents. A fishy smelling fish oil supplementation means it is rancid. rancid fish oil is not going to help your heart at all and may actually hurt it.

 

Q. That leaves CoQ10. Why is it important for Jane and Earl?

A. CoQ10, also known as ubiquinone, is the premier heart supplement! CoQ10 is part of our energy producing system. It works directly in the mitochondria of each cell. Mitochondria are highly specialized structures within each cell and are often referred to as powerhouses. These tiny energy producers generate 95% of the energy the body requires. The number of mitochondria in a cell depends on its function and energy needs. The heart has very important functions and requires a vast amount of energy. Thus, the heart has a lot of mitochondria or little powerhouses.

 

CoQ10 is incredibly crucial to the health of our hearts. Especially to hearts that are pumping blood with too much cholesterol. But, in a dangerous paradox, CoQ10 levels can become dangerously depleted when physicians treat high cholesterol in their patients with certain medications. The so-called “statin” drugs (Mevacor/lovastatin and Crestor/rosubastatin are two examples) are powerful and medications prescribed to lower harmful cholesterol levels. However, one very harmful side effect they share is that they deprive cells of CoQ10. While some physicians are aware of this serious side effect and tell their patients to take at least 400 mg of CoQ10 each day, most are not. The result? Any good the statin drugs may be doing is actually negated by their depletion of CoQ10.

 

Q. How does CoQ10 actually work? Has it been studied in heart disease?

A. Yes, it has! CoQ10 has been extensively studied in heart disease. This natural nutrient is present in every nucleated cell in our body (the only cells that don’t contain CoQ10 are red blood cells). Heart cells, however, are absolutely loaded with CoQ10. Its job is fairly simply – CoQ10 is vital to the production of adenosine triphosphate (ATP), the compound our body uses for 95% of its energy needs.

 

In 1998, 144 patients who had been admitted to the hospital after a heart attack, participated in a CoQ10 study. Half of the patients received 120 mg of CoQ10 a day in addition to the usual treatments given to heart attack patients. The other half, the control group, received the usual treatments and a placebo, but no CoQ10.

 

The results showed that the group taking CoQ10 had less irregular heartbeat, experienced less angina (a type of heart pain), and had much better function in the left ventricle (the most essential chamber of the heart), compared to the placebo group. Total deaths due to sudden heart failure or another heart attack were also reduced in the CoQ10 group.

 

Q. What if I have already been diagnosed with Congestive Heart Failure? Will CoQ10 still help me?

A. CoQ10 has been proven in study after study to help slow down the destruction that occurs in congestive heart failure (CHF), a serious heart disease, and heal the heart muscles damaged by heart attacks. In fact, heart attacks often occur when the body’s CoQ10 levels are low.

 

In a CHF study, patients received 100 mg of CoQ10 or a placebo twice daily for 12 weeks. Before and after the treatment period, the researchers introduced a catheter into the right ventricle of the patients’ hearts to determine the degree of muscle damage CHF had caused. In the group who took CoQ10, the pumping ability of the heart improved significantly. The placebo group’s hearts did not. The researchers conducting the study recommended that people with CHF add CoQ10 to the other medications they need to take to stay alive and well.

 

Q. Are some types of CoQ10 better than others?

A. Indeed they are. CoQ10 products are not created equally. The key to this natural medicine is the quality of the manufacturing. Take a CoQ10 supplement that’s been used in research conducted by prestigious universities (it will tell you this right on the label). Researchers want the best CoQ10 for their studies. You want the best CoQ10 for yourself and your loved ones.

 

The best CoQ10 has to meet the following criteria:

1. Must be easily absorbed during the digestion process so that it can get into the

bloodstream.

2. Must reach the mitochondria in the cell.

3. Must be proven effective in studies.

4. Must be safe and free of impurities.

 

Q. It sounds as if CoQ10 is only for people with moderate or high risk factors. Can others benefit from this supplement?

A. Many people, including those like Fred with low risk factors or no risk of heart disease take CoQ10 every day. CoQ10 supplements may reduce your risk of cancer, prevent gum disease, and help certain nerve cells work more effectively.

 

Conclusion

Understanding your personal risk factors, making it better lifestyle choices, taking a multivitamin formulated for your heart, an enteric-coated fresh garlic supplement, fish oil supplement with Omega-3 fatty acids, and CoQ10 – the heart’s super-nutrient – can help keep your heart healthy and strong.

 

Helen Keller, the famous lecturer and author, who was both blind and deaf wrote, “The best and most beautiful things in the world cannot e seen or even touched. They must be felt with the human heart.”

 

Healthy hearts have the most opportunities to “feel” the best and are the most beautiful thing our world has to offer.

 



--
Supplements To Benefit The Heart At Vitanet

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Selecting Quality Evening Primrose Oil
TopPreviousNext

Date: June 03, 2006 01:12 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Selecting Quality Evening Primrose Oil

Always look first for a certified organic source of Evening Primrose Oil. In addition, since oils are highly subject to rancidity, it is recommended that you acquire a product that is manufactured using a low temperature process without chemical solvents to avoid formation of free radicals and ensuing rancidity.

Generally, two grades of evening primrose oil have been available to consumers. The crude grade is considered to be unstable because of its high organic matter content. This oil is usually greenish color.

Refined evening primrose oil have a low organic matter content and are yellowish color. As we mentioned, oils tend to accumulate pesticides, especially the many kinds that are fat soluble. That’s why we always tell our readers to prefer organic oils. Until now few, if any, organic evening primrose oil products have been available.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1295)


WHAT IS A FREE RADICAL?
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Date: July 13, 2005 09:57 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: WHAT IS A FREE RADICAL?

WHAT IS A FREE RADICAL?

Free radicals are unstable, unpredictable structures that pose a potential threat to healthy molecules on a cellular level. In their atte mpt to become stable, they assault and randomly impact healthy molecules, altering their functions in the process.

TO COMPLETLEY ELIMINATE FREE RADICALS, YOU MUST STOP BREATHING

The very act of breathing oxygen activates these reactive chemical structures. To make matte rs wo rse, because our generation, more than any other, is exposed to a number of potentially harmful environmental substances, free radical formation can reach epidemic proportions. Some of the more dangerous of these include:

  • • cigarette smoke
  • • herbicides
  • • pesticides
  • • smog
  • • car exhaust
  • • certain prescription drugs
  • • diagnostic and therapeutic x-rays
  • • ultra-violet light
  • • gamma radiation
  • • rancid foods
  • • certain fats
  • • alcohol
  • • some of our food and water supplies
  • • stress
  • • poor diets

    EVEN EXERCISE HAS ITS PERILS

    Exercising, as beneficial as it is, can initiate the release of free radicals within our cellular systems. Aerobic exercising produces oxidation products. Many of these compounds are not neutralized by our internal safety mechanisms and an overload can occur. Supplementing the diet with efficient antioxidants is highly recommended for eve ryone, but especially for those who exercise on a regular basis.

    WHY ARE FREE RADICALS SO DANGEROUS

    A free radical can destroy a protein, an enzyme or even a complete cell. To make matte rs wo rse, free radicals can multiply through a chain reaction mechanism resulting in the release of thousands of cellular oxidants. When this happens, cells can become so badly damaged that DNA codes can be altered and immunity can be compromised.

    Contact with a free radical or oxidant on this scale can create cellular deterioration, resulting in cancer and heart disease. Tissue breakdown from this oxidative stress can also occur which can contribute to aging, arthritis and whole host of other degenerative conditions. “Through free radical reactions in our body, it’s as though we’re being irradiated at low levels all the time. They grind us down.”3

    PREMATURE AGING AND FREE RADICALS:

    Frequently, the oxidative stress caused by free radicals results in what we refer to as the aging process. While aging is inevitable, many of us hasten its outcome by not protecting ourselves, hence, we age prematurely. The early onset of wrinkling, arthritis, circulatory disorders, diabetes, heart disease and hardening of the arteries can result from free radical damage that could have been minimized by consistently taking strong antioxidants like Pycnogenol. More and more research suggests that it is a lack of certain protective nutrients, like the bioflavonoid compounds contained in Pycnogenol, which increases our risk of cancer and other degenerative diseases.4

    WHY A NUTRITIOUS DIET DOES NOT AFFORD US ENOUGH PROTECTION

    “They (antioxidants) may be much more important that doctors thought in warding off cancer, heart disease and the ravages of aging—and, no, you may not be getting enough of these nutrients in your diet.”5

    Clearly, while diet modifications are invaluable, diet alone cannot provide the kind of physiological defense the body requires to inhibit free radicals before they cause biological harm. While there is no way to escape our exposure to free radicals, we can minimize potential cellular destruction by reducing their numbers.

    (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=605)


    DO WE NEED EXTRA LIVER PROTECTION?
    TopPreviousNext

    Date: July 12, 2005 10:15 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: DO WE NEED EXTRA LIVER PROTECTION?

    DO WE NEED EXTRA LIVER PROTECTION?

    Even if you don’t suffer from any liver disease or don’t abuse alcohol, you may still require the therapeutic effects of Milk Thistle. Everything that enters the liver through the portal vein must be de-toxified and neutralized. Many of us eat diets that are too high in protein, take overthe- counter or prescription drugs, and routinely expose ourselves to radiation and other pollutants. Everything we breath, eat and absorb through our skin is purified and refined in the liver. Some of the more detrimental compounds we ingest that increase the liver’ s work load include:

  • pain killing drugs
  • heavy metals
  • excess hormones
  • saturated and rancid fats
  • metabolite waste products from biochemical reactions
  • pesticides and herbicides
  • nicotine
  • stress
  • high protein diets

    Dr. Andrew Weil, M.D. author of Natural Health, Natural Medicine says, “High protein diets impose a considerable work load on the digestive system and may contribute to feelings of fatigue and lack of energy.” The problem with protein is that the liver has to work harder to detoxify the body from the nitrogen waste which results when it is metabolized. This compound called ure a has to eventually be eliminated from the body through the kidneys.

    Most of us are routinely exposed to nicotine, toxins of various kinds and a whole host of synthetic drugs fro m ibuprofen to steroids. Most of us overeat the wrong things and pass up what’s really good for us. High fat, high sugar, high protein diets stress the liver. Overeating, especially overcooked, fatty foods puts added strain on the liver. In addition, lack of exercise has an indirect effect on the liver. When we don’t exercise, an excess of toxins can build up and has to be transformed by the liver.

    Typically, when we are exposed to chemicals which can injure the liver, the amount of glutathione in the liver d e c reases. When this substance is reduced, the liver becomes susceptible to damage. The Silymarin content of Milk Thistle keeps concentrations of glutathione in the liver elevated by up to 35%.19 The ability of the liver to detoxify the system is largely dependent on the present of glutathione.

    According to the American Liver Foundation, liver diseases are the fourth leading cause of death up to the age of 65. It is not commonly known that a significant incidence of liver disease exists in this country. In the past, liver disease was only associated with chronic alcoholics. Now, however, liver disease strikes obese people, social drinkers and people who eat poorly. Milk Thistle can help prevent the subtle kind of liver damage any of us may be susceptible to.

    (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=589)


    HAWAIIAN NONI (Morinda citrifolia)
    TopPreviousNext

    Date: July 11, 2005 08:50 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: HAWAIIAN NONI (Morinda citrifolia)

    INTRODUCTION

    In a time when we are more concerned than ever with issues of health, a tried and true tropical herb called noni needs t o be added t o our list of the best natural remedies. It susage over hundreds of years supports it s description as a veritable panacea of therapeutic actions. At this writing, noni continues to accrue impressive medicinal credentials, and its emergence as an effective nat ural healing agent is a timely one. Amidst rising cancer rates, the high incidence of degenerative diseases like diabetes, and the evolution of ant ibiotic resist ant bacteria and new viral strains, herbs like noni are sought after for their natural pharmaceutical properties. Unquest ionably, all of us want to know how to:

  • • protect ourselves f rom toxins and pollut ants
  • • prevent t he premature onset of age-related diseases such as arthritis, heart disease, diabetes and stroke
  • • boost our immune defenses to protect ourselves from new viral and bacterial strains that have become antibiotic-resist ant
  • • reduce our risk of developing cancer
  • • better digest our food for proper assimilation and purge the intestinal system wit hout the dangerous side effects of harsh drugs. Its actions are multifaceted and must be considered when assessing natural treatment s for disease or injury. It s impressive and widespread use among various native cult ures of t ropical island regions supports the notion that it does indeed possess valuable, therapeutic compounds.

    Genus Rubiaceae

    Common Names

    Indian Mulberry (India), Noni (Hawaii), Nono (Tahiti and Raratonga), Polynesian Bush Fruit, Painkiller Tree (Caribbean islands), Lada (Guam), Mengkudo (Malaysia), Nhau (Southeast Asia), Grand Morinda (Vietnam), Cheesefruit (Australia), Kura (Fiji), Bumbo (Africa) Note: This is only a small sampling of vernacular names for Morinda citrifolia. Almost every island nation of the South Pacific and Caribbean has a term for this particular plant . This booklet will refer to the herb mainly as “ noni” or M. citrifolia, and is referring primarily to Hawaiin noni.

    Parts Used

    The parts of the noni plant most used for their medicinal and nutritional purposes are the fruit, seeds, bark, leaves, and flowers. Virtually every part of the noni plant is utilized for its individual medicinal properties; however, it is the fruit portion that is regarded as its most valuable. The seeds have a purgative action, the leaves are used to treat external inflammations and relieve pain, the bark has strong astringent properties and can treat malaria, the root extracts lower blood pressure, the flower essences relieve eye inflammations and the f ruit has a number of medicinal actions.

    Physical Description

    Morinda citrifolia is technically an evergreen shrub or bush, which can grow to heights of fifteen to twenty feet . It has rigid, coarse branches which bear dark, oval, glossy leaves. Small white fragrant flowers bloom out of cluster-like pods which bear creamy-white colored fruit. The fruit is fleshy and gel-like when ripened, resembling a small breadf ruit . The flesh of the fruit is characterist ically bitter, and when completely ripe produces a rancid and very dist inctive odor. Noni has buoyant seeds that can float formont hs in ocean bodies. The wood of the inflammatory, astringent, emollient, emmenagogue, laxative, sedative, hypotensive (lowers blood pressure) , blood purif ier, and tonic.

    Chemical Constituents

    Noni has various chemical constituents. First, it has an impressive array of terpene compounds, three of which—L. Asperuloside, aucubin, and glucose— have been identified by their actyl derivatives. Both caproic and caprylic acids have been isolated.1 Second, bushfruits, a category of which noni fruit is a member, are also considered a good source of vit - amin C.2 Third, Hawaiin noni has been linked to the synthesis of xeronine in the body which has significant and widespread health implications. Last , the alkaloid cont ent of the noni fruit is thought to be responsible for its therapeutic actions. Alkaloids exhibit a wide range of pharmacological and biological act ivitiesin the human body. They are nitrogencontaining organic compounds which can react with acids to form salts and which are the basis of many medicines. The following is an in-depth chemical analysis of each plant part and it s chemical constituents.

  • • amino acids (which include alanine, arginine, asparticacids, cysteine, cystine, glycine, glutamic acid, histidine, leucine, isoleucine, methionine, phenylalanine, proline, serine, threonine, tryptophan tyrosine, and valine)
  • • anthraquinones
  • • glycosides
  • • phenolic compounds
  • • resins
  • • B-sitosterol
  • • ursolic acid

    FLOWER

  • • acacet in 7-0-D (+) -glucophyranoside
  • • 5,7,-dimet hylapigenin-4-0-8-D(+) -galactophyranoside
  • • 6,8,-dimet hoxy-3-methyl anthroquinone-1-0-8-rhamnosyl glucophyranoside

    FRUIT

  • • antioxidant
  • • alizarin
  • • anthraquinones
  • • caproic and caprylic acids

    discovered an alkaloid in the Hawaiin noni fruit which he calls proxeronine and which he believes has appreciable physiological actions by acting as a precursor to xeronine, a very crucial compound (see later sections) . In addition, a compound found in the fruit called damnacanthol is believed to help inhibit cert ain viruses and cellular mutations involved in cancer.

    ROOT AND ROOT BARK

  • • carbonate
  • • chlorubin
  • • rubicholric acid
  • • soranjidol
  • • chrysophanol
  • • phosphate
  • • magnesium
  • • ferric iron
  • • sodium
  • • glycosides
  • • morinadadiol
  • • morindine
  • • resins
  • • rubiadin
  • • sterols4

    Pharmacology

    Recent surveys have suggested that noni fruit exerts antibiotic action. In fact, a variety of compounds which have antibacterial properties (such as aucubin) have been identified in the fruit.5 The 6-Dglucopyranose pentaacet ate of the fruit extract is not considered bacteriostatic.6 Constituents found in the fruit portion have exhibited ant imicrobial action against Escherichia coli, Salmonella typhi (and other types) , Shigella paradysenteriae, and Staphylococcus aureaus. Compounds found in the root have the ability to reduce swollen mucous membrane and lower blood pressure in animal studies. Proxeronine is an alkaloid constituent found in Hawaiin noni fruit which may prompt the production of xeronine in the body. It is considered a xeronine precursor and was discovered in noni fruit by Dr. Ralph M. Heinicke. He has theorized that this proenzyme can be effective in initiating a series of beneficial cellular reactions through its involvement with the integrity of specific proteins. He points out that tissues contain cells which possess certain recept or sites for xeronine. Because the reactions that can occur are so varied, many different therapeutic actions can result when xeronine production escalates, explaining why Hawaiin noni is good for so many seemingly unrelated disorders. Damnacanthol is another compound contained in the fruit of the Hawaiin noni plant which has shown the ability to block or inhibit the cellular function of RAS cells, considered pre-cancerous cells.

    Body Systems Targeted

    The following body systems have all been effec-freeze-dried capsules, dehydrated powder or fruit, and oil. Noni plant constituents are sometimes offered in combination with other herbs. Some products contain a percent age of the fruit, bark, root and seeds for their individual therapeutic properties.

    Satety

    Extracts of M. citrifolia are considered safe if used as directed; however, pregnant or nursing mothers should consult their physicians before taking any supplement . High doses of root extracts may cause constipation. Taking noni supplements with coffee, alcohol or nicotine is not recommended.

    Suggested Uses

    Ideally, noni extracts should be taken on an empty stomach prior to meals. The process of digesting food can interfere with the medicinal value of the alkaloid compounds found in Hawaiin noni, especially in its fruit . Apparently, stomach acids and enzymes destroy the specific enzyme which frees up the xeronine compound. Take noni supplements without food, coffee, nicotine or alcohol. Using supplements that have been made from the semi-ripe or light - green fruit is also considered preferable to the ripe, whit ish fruit .

    NONI: ITS USE AND HISTORY

    Noni is a tropical wandering plant indigenous to areas of Australia, Malaysia and Polynesia. It is considered native to Southeast Asia although it grows from India to the eastern region of Polynesia. Morinda citrifolia has a long history of medicinal use throughout these areas. It is thought to be the “most widely and commonly used medicinal plant prior to the European era.” 7 Centuries ago, the bushfruit was introduced to native Hawaiians, who subsequently called it “noni” and considered its fruit and root as prized medicinal agents. Among all Polynesian botanical agents of the 19th and 20th centuries, Hawaiin noni has the widest array of medical applications. Samoan and Hawaiian medical practitioners used noni for bowel disorders (especially infant diarrhea, constipation, or intestinal parasites) , indigestion, skin inflammation, infection, mouth sores, fever, contusions and sprains. Hawaiians commonly prepared noni tonics designed to treat diabetes, stings, burns and fish poisoning.8 The herb’s remarkable ability to purge the intestinal tract and promote colon health was well known among older Hawaiian and Tahitian natives and folk healers. Interestingly, field observations regarding its repu-remarkable healing agent .

    Wonder Herb of Island Folk Healers

    Common to t he thickets and forests of Malaysia and Polynesia, and the low hilly regions of the Philippine islands, noni has been cultivated throughout communities in the South Pacific for hundreds of years. Its Hawaiian use is thought to originate from inter-island canoe travel and settlement dating to before Christ . Its hardy seeds have the ability to float which has also contributed to its distribution among various seacoasts in the South Pacific region. Historical investigation has established the fact that some of Hawaii’s earliest settlers probably came viaTahiti. For this reason, Tahitian herbal practices have specific bearing on the herbal therapeutics of islands to the nort h. The very obvious similarities between the Hawaiian vernacular for herbal plants like noni and Tahitian names strongly suggests the theory of Polynesian migrations to Hawaii. Cultures native to these regions favored using Morinda citrifolia for treating major diseases and ut ilized it as a source of nourishment in times of famine.9 Noni fruit has been recognized for centuries as an excellent source of nutrition. The peoples of Fiji, Samoa and Rarat onga use the fruit in both its raw and cooked forms.10 Traditionally, the fruit was propicked before it was fully ripe and placed in the sunlight . After being allowed to ripen, it was typically mashed and its juice extracted through a cloth. Noni leaves provided a veget able dish and their resiliency made them desirable as a fish wrap for cooking.

    Noni’s Medical Reputation

    Elaborate traditionalrituals and praying rites usually accompanied the administration of noni. Int erestingly, cultures indigenous to the Polynesian islands had a significant understanding of their flora. For example, native Hawaiians maint ained a folkmedicine taxonomy t hat was considered second to none.11 Noni was not only used for medicinal purposes but for its food value, for clot hing and for cloth dyes as well. Research indicates that noni was among the few herbal remedies that islanders considered “ tried and true.” In Hawaii, trained herbal practitioners reserved the right to prescribe plant therapies.12 Records indicate that Hawaiian medical practices were based on extensive and very meticulous descriptions of symptoms and their prescribed herbal treatments. Dosages were controlled and the collection and administration of plant extracts was carefully monitored.13 In addition to Morinda, it was not uncommon for these herbal doctors to also recommend using In regard to its application for common ailments, Hawaiians and other island communities traditionally prescribed noni to purge the bowel, reduce fever, cure respiratory infections such as asthma, ease skin inflammations, and heal bruises and sprains. In other words, noni was widely used and highly regarded as a botanical medicine.

    A Timely Reemer gence

    Today, the natural pharmaceutical actions of the chemical constituents contained in noni are scientif-ically emerging as valuable bot anical medicines. Tahitian “nono” intrigued medical practitioners decades ago; however, due to the eventual emergence of synthetic drugs, interest in this island botanical diminished until recent years. Ethnobot anists are once again rediscovering why Hawaiian people havet reasured and cultivat ed Morinda citrifolia for generations. Noni is now finding its way into western therapeutics and is referred to as “ the queen” of the genus Rubiaceae. Its ability to reduce joint inflammation and target the immune system have made it the focus of the modern scientific inquiry. Dr. Ralph Heinicke has conducted some fascinating studies on the chemical constituents of the Hawaiin noni fruit. His research centers on the proxeronine content of the fruit juice and how it profoundly influences human physiology. In addition, scientific studies investigating noni as an anti-cancer agent have been encouraging. It s conspicuous attributes and varied uses have elevat edits status to one of the best of the healing herbs. Today Morinda citrifolia is available in liquid, juice, freezedried capsules, or oil forms, and is considered one of nature’s most precious botanicals.

    TRADITIONAL USES OF NONI

    Throughout tropical regions, virtually every part of Morinda citrifolia was used to treat disease or injury. Its curative properties were well known and commonly employed. PatoaTama Benioni, a member of the Maoritribe from the Cook Islands and a lecturer on island plants explains: Traditionally Polynesians use noni for basically everything in the treatment of illness. Noni is a part of our lives. Any Polynesian boy will tell you he’s had exper ience with it . We use juice from its roots, its flowers, and its fruit... my grandmother taught me to use noni from the roots and the leaves to make medicine for external as well as internal use, and for all kinds of ailments, such as coughs, boils, diseases of the skin, and cuts.15

    decoctions to stimulate delayed menst ruation.

  • • Noni was frequently utilized for its antiparasitic activity.
  • • Respiratory ailments, coughs, and colds were treated with noni.
  • • A juice made from pounding noni leaves, roots and fruit mixed with water was administered for diarrhea.
  • • Dried and powdered forms of the bark mixed with water and administ ered with a spoon treated infant diarrhea.
  • • Small pieces of fruit and root infused with water were given to kill intestinal parasites.
  • • Boiled bark decoctions were given as a drink for stomach ailments.
  • • Coughs were treated with grated bark.
  • • Charred unripe fruit was used with salt on diseased gums.
  • • Pounded fruit combined with kava and sugar cane was used to treat tuberculosis.
  • • Babies were rubbed with fresh, crushed leaves for serious chest colds accompanied by fever.
  • • Eye washes were made from decoctions for eye complaint s from flower extracts.
  • • Leaf infusions were traditionally taken to treat adult fevers.
  • • A mouthwash consisting of crushed ripe fruit and juice was used for inflamed gums in young boys.
  • • Pounded leaf juice was used for adult gingivitis.
  • • Sore throats were treated by chewing the leaves and swallowing the juice.
  • • Skin abscesses and boils were covered with leaf poultices.
  • • Swelling was controlled with leaf macerations.
  • • Heated leaves were often used for arthritic joins and for ringworm.16

    XERONINE: THE SECRET OF NONI?

    One informed professional on the subject of noni is Dr. Ralph Heinicke, a biochemist who has researched the active compounds of noni fruit for a number of years. He discovered that the Hawaiin noni fruit contains an alkaloid precursor to a very vital compound called xeronine. Wit hout xeronine, life would cease. In Dr. Heinicke’s view, noni fruit provides a safe and effective way to increase xeronine levels, which exert a crucial influence on cell health and protction. His research suggests that the juice from the M. citrifolia fruit contains what could technically be considered a precursor of xeronine—proxeronine. This compound initiates the release of xeronine in the intestinal tract after it comes in contact with a specific enzyme which is also contained in the fruit .

    Because proteins and enzymes have so many varied roles within cell processes, the normalization of these proteins with noni supplemenation could initiate avery wide variety of body responses and treat many disease condit ions. Proteins are the most important catalysts found in the body. The beauty of obtaining a precursor to xeronine from the noni fruit is that the body naturally decides how much of this precursor to convert to xeronine. Disease, stress, anger, trauma and injury can lower xeronine levels in the body, thus creat ing a xeronine deficit . Supplementing the body with noni fruit is considered an excellent way to safely and naturally raise xeronine levels. It is the research and theories of Dr. Heinicke which have made the juice of the Hawaiin noni fruit a viable medicinal substance. He writes: Xeronine is analkaloid, a substance the body produces in order to activate enzymes so they can function properly. It also energizes and regulates the body. This par-ticular alkaloid has never been found because the body makes it, immediately uses it, and then breaks it down. At no time is there an appreciable, isolable amount in the blood. But xeronine is so basic to the functioning of proteins, we would die without it . Its absence can cause many kinds of illness.17 Because so many diseases result from an enzyme malfunction, Dr. Heinicke believes that using the noni fruit can result in an impressive array of curative applications. Interestingly, he believes that we manufacture proxeronine while we are sleeping. He proposes t hat if we could constantly supply our bodies wit h proxeronine from other sources, our need to sleep would diminish.18

    NONI PROCESSING

    How an herb is processed is crucial to how beneficial it is: this is especially true of noni, with its unique enzymes and alkaloids. Morinda citrifolia should be picked when the fruit is turning from its dark green immature color to its lighter green color, and certainly before it ripens to its white, almost translucent color. Once picked, noni, like aloe, will denature extremely quickly due to its very active enzymes. After harvesting, it should swiftly be flash frozen. This is similar to what is done to fish caught at sea to keep them f esh. This stops it from losing its potency while not damaging any of its constituents. To process noni, freeze-drying is recommended. This removes only the water without damaging any of this miracle plant’s vital enzymes and other phytonutrients like xeronine and proxeronine. This pure high-quality noni fruit juice powder is then encapsu-has a very harsh taste and an extremely foul smell, similar to the fruit it self . Other methods of processing include thermal processing, dehydrat ion and air drying. Thermal processing is generally found in liquids, while the dehydrat ed noni is then milled and encapsulated. Unfortunately both methods utilize high heat (110+°F) , which can deactivate many of the vital compounds that make noni so import ant . Air-drying is effect ive without using damaging heat but has serious quality control problems for commercial production.

    MODERN APPLICATIONS OF NONI

    Overview

    Noni possesses a wide variety of medicinal properties which originat e from its differing plant component s. The fruit and leaves of the shrub exert antibacterial activities. Its roots promote the expulsion of mucus and the shrinkage of swollen membranes making it an ideal therapeutic for nasal congest ion, lung infect ions, and hemorrhoids. Noni root compounds have also shown natural sedative properties as well as the ability to lower blood pressure.

    Leaf extracts are able to inhibit excessive blood flow or to inhibit the formation of blood clots. Noni is particularly useful for its ability to treat painful joint conditions and to resolve skin inflammations. Many people drink noni fruit extracts in juice form for hypert ension, painful menstruation, arthritis, gastric ulcers, diabetes, and depression. Recent studies suggest that its anticancer activit y should also be considered. Concerning the therapeutic potential of the Hawaiin noni fruit, Dr. Heinicke writes: I have seen the compound found in noni work wonders. When I was still investigating its possibilities, I had a friend who was a medical research scientist administer the proxeronine to a woman who had been comatose for three months. Two hour safter receiving the compound, she sat up in bed and asked where she was. . . . Noni is probably the best source of proxeronine that we have today.19 Studies and surveys combined support the ability of noni to act as an immunost imulant, inhibit the growth of certain tumors, enhance and normalize cellular function and boost tissue regeneration. It is considered a powerful blood purifier and contributor to overall homeostasis.

    xeronine, which appears to be able to regulate the shape and integrity of cert in proteins that individually contribute to specific cellular activities. Interestingly, this effect seems to occur after ingestion, inferring that the most active compound of noni may not be present in uneaten forms of the fruit or other plant parts. Some practitioners believe that xeronine is best obtained from a noni fruit juice precursor compound. The enzymatic reactions that occur with taking the juice on an empty stomach are what Dr. Heinicke believes set cellular repair intomotion.

    Cancer

    A study conducted in 1994 cited the anticancer activity of Morinda citrifolia against lung cancer. A team of scientists from the University of Hawaii used live laboratory mice to test the medicinal properties of the fruit against Lewis lung carcinomas which were artificially transferred to lung tissue. The mice that were left untreated died in nine to twelve days. However, giving noni juice in consistent daily doses significantly prolonged their life span. Almost half of these mice lived for more than fifty days.20 Research conclusions state that the chemical constituents of the juice acted indirectly by enhancing the ability of the immune system to deal with the invading malig-nancy by boosting macrophage or lymphocyte activit y. Furt her evaluation theorizes that the unique chemical constituents of Morinda citrifolia initiate enhanced T-cell activity, a reaction that may explain noni’s ability to treat a variety of infectious diseases. 21

    In Japan, similar studies on tropical plant extracts found that damnacanthol, a compound found in Morinda citrifolia, is able to inhibit the function of KRAS- NRK cells, which are considered precursors to certain types of malignancies.22 The experiment involved adding noni plant extract to RAS cells and incubating them for a number of days. Observation disclosed that noni was able to significantly inhibit RAS cellular function. Among 500 plant extracts, Morinda citrifolia was determined to contain the most effective compounds against RAS cells. Its damnacanthol content was clinically described in 1993 as “a new inhibit or of RAS function.” 2 3 The xeronine fact or is also involved in that xeronine helps to normalize the way malignant cells behave. While they are still technically cancer cells, they no longer function as cells with unchecked growth. In time, the body’s immune system may be able to eradicate these cells.

    Arthritis

    with arthritic disease. One link to arthritic pain may be the inability to properly or completely digest proteins which can then form crystal-like deposits in the joints. The ability of noni fruit to enhance protein digestion through enhanced enzymatic function may help to eliminate this particular phenomenon. In addition, the alkaloid compounds and plant met abolites of noni may be linked to its apparent anti-inflammatory action. Plant sterols can assist in inhibiting the inflammatory response which causes swelling and pain. In addition, the antioxidant effect of noni may help to decrease free radical damage in joint cells, which can exacerbate discomfort and degeneration.

    Immune System

    The alkaloid and other chemical compounds found in noni have proven themselves to effectively control or kill over six types of infectious bacterial strains including: Escherichia coli, salmonellatyphi (and other types) , shigella paradysenteriae, and staphylo - coccus aureaus.25 In addition, damnacanthol, was able to inhibitt he early antigen stage of the Epstein- Barr virus.

    The bioactive components of the whole plant, combined or in separate portions, have demonst rat - ed the ability to inhibit several different strains of bacteria. Anecdotal reports support this action in that noni seems particularly effective in shortening the duration of certain types of infection. This may explain why noni is commonly used to treat colds and flu. The chemical constituents found in noni and the possibility that they stimulate xeronine production— as well as initiate alkaloid therapy—may explain noni’s reputation for having immuno-stimulatory properties. Alkaloids have been able to boost phagocytosis which is the process in which certain white blood cells called macrophages attack and literally digest infectious organisms. Interestingly, the ant it umoraction of noni has been ascribed to an immune system response which involves stimulating T-cells. tropical regions during World War II learned of the fruit’s ability to boost endurance and stamina. Native cultures in Samoa, Tahiti, Raratonga and Australia used the fruit in cooked and raw forms. M. citrifolia is considered a tonic and is especially recommended for debilitated conditions.

    Antioxidant

    The process of aging bombards the body with free radicals which can cause all kinds of degenerative diseases. The xeronine theory promoted by Dr. Heinicke submit s t hat as our bodies age, we lose our ability to synthesize xeronine. To make matters worse, the presence of many environment altoxins actually blocks the production of xeronine as well. He believes that the proxeronine content of Hawaiin noni fruit juice can help to block these actions, thereby working as an antiaging compound.26 The phytonutrients found in noni assist in promot - ing cell nourishment and prot ect ion from free radicals created by exposure to pollution and other potentially damaging agents. In addition, Morinda citrifolia contains selenium, which is considered one of the best antioxidant compounds available.

    Diabetes

    While scientific studies are lacking in this particular application of noni, Hawaiians used various parts of the plant and its fruit to treat blood sugar disorders. Anecdotal surveys have found t hat noni is current ly recommended for anyone with diabetes.

    Pain Killer

    A 1990 study found that extracts derived from the Morinda citrifolia root have the ability to kill pain in animal experiments.27 Interest ingly, it was during this study that the natural sedative action of the root was also noted. This study involved a French team of scientists who noted a significant central analgesic activity in laboratory mice.28 Dr. Heinicke has stated, “Xeronine also acts as a pain reliever. A man wit h very advanced int est inal cancer was given three months to live. He began taking the proxeronine and lived for a whole year, pain-free.” 29

    Skin Healing Agent

    One of the most prevalent hist rical uses of noni was in poultice form for cuts, wounds, abrasions, burns and bruises. Using its fruit extract for very serious burns has resulted in some extraordinary healing. Because skin is comprised of protein, it immediately responds to the presence of xeronine.

    burn site throught he direct application of a noni poultice is considered quite effective by Dr. Heinicke and his colleagues, who have studied enzymatic therapy. Concerning burns, he has written: I believe that each tissue has cells which contain proteins which have receptor sites for the absorption of xeronine. Certain of these proteins are the inert for ms of enzymes which require absorbed xeronine to become active. This xeronine, by converting the body’s procol- langenase system into a specific protease, quickly and safely removes the dead tissue from burns.30

    Drug Addiction

    The xeronine link to treat ing drug addiction is based on the notion that flooding t he brain with extra xeronine can reverse the neurochemical basis for addiction. This natural alkaloid is thought to normalize brain receptors which subsequent ly results in the cessation of physiological dependence on a certain chemical like nicotine.3 1 The potential of Hawaiin noni as a natural stimulat or for t he production of xeronine may have profound implications in treating various types of addictions.

    Complementary Agents of Noni

  • cat’s claw papaya
  • kava kava
  • pau d’arco
  • bioflavonoids
  • selenium
  • germanium
  • grapeseed extract
  • echinacea
  • proteolytic enzymes
  • aloe vera
  • glucosamine
  • shark
  • cartilage

    PrimaryApplications of Noni

  • abrasions
  • arthritis
  • atherosclerosis
  • bladder infections
  • boils bowel disorders
  • burns cancer
  • chronicfatigue syndrome
  • circulatory weakness
  • colds congest ion
  • cold sores constipation
  • depression diabetes
  • eye inf lammations fever
  • fract ures gastric ulcers
  • gingivit is headaches
  • high blood pressure immune
  • weakness
  • indigestion intestinal parasites
  • kidney disease menstrual



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    GARLIC AS AN ANTIOXIDANT
    TopPreviousNext

    Date: June 25, 2005 10:20 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: GARLIC AS AN ANTIOXIDANT

    GARLIC AS AN ANTIOXIDANT

    The term “antioxidant” has become a buzz word over the last decade. Defending ourselves against a wide array of chemicals, heavy metals, pollutants, radiation and poor nutrition has become a vital area of scientific focus and research. Oxidizing agents or free radicals attack our bodies constantly and have the potential to damage our cells, which compresses human tissue.

    Substances which have been found to help protect us from the cellular damage caused by free radicals include vitamin C, bioflavonoids, vitamin E, vitamin A, beta carotene and selenium to name a few. Garlic is not usually found on standard antioxidant lists and probably should be.

    Garlic has an abundance of sulfhydryl which is an excellent antioxidant. It’s important to know that raw garlic did not demonstrate this ability. In fact, raw garlic actually has some oxidant action, which is not desireable. Garlic can also help to lessen free radical damage because it has the ability to protect against radiation. In this regard, it may significantly decrease our risk of developing certain degenerative diseases such as cancer and premature aging. In addition, anyone undergoing radiation or chemotherapy should supplement their diet with garlic. “Based on a number of studies conducted by research teams from throughout the world, scientists have concluded that part of the preventive effect of garlic against cancer is due to protection against free radical damage. But that protection extended beyond the mere ability to protect against disease. The ability of garlic to protect against free radical damage may have yet another important benefit to cancer victims: it can, according to several published articles, protect against the damage that results from radiation treatment and chemotherapy commonly given to many cancer patients.” 44 Garlic also contains a number of amino acids which are required for the formation of an enzymatic antidote to free radical pathology which is created by cigarette smoke and other pollutants. Cysteine, glutamine, isoleucine and methionine found in garlic help to protect the cells from free radical damage.

    Garlic works as an antioxidant the same way that onions, and green chilies do. In his book The Miracle of Garlic, Paavo Airola states:

    “An Indian study showed that garlic exhibited a high antiox idant property as determined by the peroxide values of the products by the swift stability test. Garlic restrained the development of all characteristic indexes of rancidity (acids, peroxides, iodine no. etc.). Garlic retained its antioxidant property for a half year after harvesting.”45

    Because our food, air, water and environments are heavily contaminated with pollutants of all kind including food additives, preservatives, artificial colorings, flavorings, sweeteners, chemical fertilizers, etc., garlic should become a permanent addition to our nutritional array of supplements.

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    Fats for Life - the quality of the fat you eat is probably much more important than the...
    TopPreviousNext

    Date: June 12, 2005 02:39 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Fats for Life - the quality of the fat you eat is probably much more important than the...

    Fats for Life by Henry Wolfe Energy Times, August 6, 2003

    For years, many experts argued that the only good fatty foods were the ones you didn't eat. That was a big, fat mistake. Overwhelming evidence now shows that certain fats are not only necessary for optimal health, but that the quality of the fat you eat is probably much more important than the quantity.

    Threatening Trans Fats

    "The biggest thing wrong with the fats Americans eat today is that they are eating too many trans fatty acids," says Fred Pescatore, MD, author of The Allergy and Asthma Cure (John Wiley). "About 42,000 foods contain trans fats. These fats are linked to a higher risk of heart disease, stroke and cancer."

    Trans fatty acids are fats that form when food manufacturers add hydrogen to fat molecules, a process called hydrogenation that makes fats stay fresh longer without growing rancid. Trans fats also form when foods are fried.

    Hydrogenation extends the shelf life of refined foods like cakes, donuts, and crackers. Unfortunately, it also creates fats that many experts believe can compromise your health. In a study of the health effects of trans fats, 26 people agreed to eat a diet that changed every five weeks, continually shifting the types of fats in their meals (American Heart Association's Scientific Sessions 2000). All of the diets in the study provided 30% of calories from fat. One fifth of the fat came from either soybean oil, semi-liquid margarine, tub margarine, shortening, stick margarine or butter.

    "We were interested in assessing what would happen when we substituted one fat for another," notes researcher Alice H. Lichtenstein, DSc, professor of human nutrition at Tufts University, Boston.

    The study showed that as people ate more trans fatty acids (in the more solid margarines) and fewer polyunsaturated fats (in the liquid oils), their triglycerides increased after each meal. Triglycerides are blood fats that boost heart disease risk.

    For instance, when these folks ate stick margarine, which is high in trans fats, their triglycerides climbed an average 18% higher than when they ate semi-liquid squeeze bottle margarine, a type of margarine that is softer because it is less hydrogenated. Stick margarine raised heart disease risk by causing a drop in HDL, or "good" cholesterol. Although butter increased HDL, it also caused a significant increase in LDL, the "bad" cholesterol that raises heart disease risk.

    Dietary Advice

    "The best dietary advice we can give people is to minimize their intake of animal and hydrogenated fats in order to reach the American Heart Association's target of 10% or less of total calories from saturated fat and trans fatty acids," Dr. Lichtenstein says. "That would mean consumers choosing low-fat and non-fat dairy products and lean cuts of meat, and the food industry decreasing the amount of hydrogenated fats used in their products." According to a study at Johns Hopkins University (Amer Coll of Card, 52nd Scientific Session, 3/30/03, Chicago), people who eat saturated fat have more visceral fat, fat surrounding their internal organs. This fat around the waist is now seen as a risk factor for heart disease and other illnesses.

    Another hidden problem in our fat consumption, according to Dr. Pescatore, hides within canola oil. Dr. Pescatore says that although many consumers believe canola oil is beneficial to health, the refined canola oil sold in the US has had its potential health benefits removed during processing.

    "People still think canola oil is healthy and eat too much of it," he says. "The problem with canola is that it is highly processed and refined....Processors hydrogenate canola oil to keep it from getting rancid."

    According to Fred Ottoboni, PhD, coauthor of The Modern Nutritional Diseases (Vincente Books), "Canola oil is lightly hydrogenated to take out the omega-3 fatty acids (the healthiest, but most unstable, fats) and then the food manufacturers filter the trans fats out. I don't worry about the trans fats in canola, but the problem is the huge ratio of omega-6 fatty acids to omega-3s."

    To get more of the omega-3 fatty acids, which are lacking in most Americans' diets, Dr. Pescatore advocates using macadamia nut oil. "Macadamia nut oil is higher in monounsaturated fats than olive oil; it is the healthiest fat with an omega-3 to -6 ratio of one to one."

    The Omega-3 Difference

    Omega-3 and omega-6 fatty acids are basic forms of fat found in oils. Fish oil, hempseed and flax oil are high in what are called omega-3s. Certain plant-derived oils like corn and soy are richer in omega-6 fatty acids.

    "Primitive humans ate a diet that contained a one-to-one ratio of omega-3s and omega-6s," says Dr. Pescatore. "Today we (Americans) eat 20 times more omega-6 than -3; that's why we suffer so much chronic disease and chronic inflammation. For instance, the Japanese eat a (much better) diet that contains a two-to-one ratio of omega-6 fatty acids to omega-3." "Not all omega-6s are bad," he adds, "we just eat too many of them."

    Switching to healthier fat isn't hard. Eat more fish. When cooking, stick to oils like olive oil and macadamia oil. The quality of your oil and your health may improve in a big, fat way.



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    Neptune Krill Oil (NKO) - for Healthy Heart, Joints, and other Body systems
    TopPreviousNext

    Date: June 03, 2005 05:43 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Neptune Krill Oil (NKO) - for Healthy Heart, Joints, and other Body systems

    Neptune Krill Oil

    Essential fatty acids are enormously important to your health. They are the building blocks for phospholipids, and phospholipids are the building blocks for your cell membranes – the protective layer and gatekeeper of your cells. A good essential fatty acid balance provides building blocks for healthy cells, but an imbalance can lead to critical health concerns. Source Naturals introduces NKO™ Neptune Krill Oil, the first product featuring phospholipids specially integrated with omega-3 essential fatty acids for building healthy cell membranes. It also includes antioxidant protection. In human studies, NKO supplementation supported healthy joints, the heart, lipid and blood sugar levels, energy production, athletic performance and liver function, and eased women’s PMS symptoms.

    Support Your Protective Cell Membranes

    Source Naturals brings you the science of natural NKO™ Neptune Krill Oil, the only product to boast significant healthinducing potencies from three different important nutritional categories: omega- 3 fatty acids, phospholipids and antioxidants. These three nutrients work together to support healthy cell membranes, joints, the heart and many other body systems. And NKO eases PMS symptoms for women.

    Multiple Benefits of Krill

    NKO™ Neptune Krill Oil has many benefits. Unlike fish oil products, NKO doesn’t contain dangerous levels of mercury or lead, doesn’t go rancid quickly and has a clean, fresh taste. Made from hearty krill, shrimp-like crustaceans that thrive in the harsh Antarctic waters, it is the only product to contain phospholipids specially integrated with omega-3 essential fatty acids. This unique structure provides important cell membrane building blocks in the ratios used by the body and may be far better utilized than stand-alone phospholipid or omega- 3 products. The result: stronger cell membranes that function better to maintain your health. The desirable composition of NKO, high in omega-3 essential fatty acids, also provides a healthy balance. High levels of omega-6 fatty acids, such as from processed foods, enable your cell membranes to initiate over-production of certain prostaglandins that can lead to cellular irritation, heart system imbalances and other concerns. But omega-3 fatty acids can reverse that trend. Omega-3 fatty acids such as DHA and EPA (docosahexaenoic and eicosapentaenoic acids) compete with arachidonic acid for building blocks, such as the COX-2 enzyme, and can instead lead to balanced levels of the many different types of prostaglandins. The result: cellular comfort, heart health and many other healthy body systems. NKO also contains natural antioxidants, which are cell membrane protectors. Each serving contains 100 IU of vitamin A and a very high level, 1.5 mg, of astaxanthin, an immune-supporting carotenoid, which can be used to guard your cell membranes from free radical damage. And NKO 100% pure krill oil is manufactured by Neptune Technologies & Bioresources Inc. in adherence to all environmental harvesting standards. Source Naturals is pleased to partner with your local health food store to bring you NKO™ Neptune Krill Oil. Try this unique, potent and comprehensive product for your better health today.

    References
    Drevon, C. A. (1992). Nutr Rev. (50): 38-45. Horrobin, D. F. (1983). J Reprod Med. (28): 465-468. Simopoulos, A. P. (1991). Am J Clin Nutr. (54): 438-463.



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    Heart Science - A Five-Tiered Approach to Heart Health ...
    TopPreviousNext

    Date: June 02, 2005 12:07 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Heart Science - A Five-Tiered Approach to Heart Health ...

    Heart Science 30 tabs

    Your heart is crucial to every function of your body. It is the sole organ which pumps oxygen-rich blood through the entire circulatory system, feeding your cells and making life possible. Only recently are Americans realizing the importance of a proper low-fat diet, regular exercise, giving up cigarette smoking, and cutting down alcohol consumption to maintaining a healthy heart. Unfortunately, there has been a huge gap in the number of nutritional supplements which provide nutrients and herbs to support normal heart function. That’s where Source Naturals HEART SCIENCE comes in. Two years in the making, and backed by numerous scientific studies, the nutrients in HEART SCIENCE are some of the most soundly researched of all. Combining high potencies of these super-nutrients, HEART SCIENCE is the most comprehensive, cutting edge nutritional approach to proper heart care available.

    Source Naturals HEART SCIENCE— The Five Tiered Approach to Heart Health

    Your heart never rests. Even while you sleep, your heart must keep working, relying on the constant generation of energy by the body for its very survival. If this vital organ stops beating for even a short amount of time, all bodily functions cease and life ends. Source Naturals HEART SCIENCE helps support heart function on the chemical, cellular, structural, and energetic levels. This broad spectrum formula includes ingredients specifically geared for
    1) generating energy,
    2) decreasing harmful homocysteine levels,
    3) fighting oxidized cholesterol,
    4) maintaining the heart’s electrical rhythm, and
    5) protecting artery and capillary linings.

    Energy Generators for An Energetic Organ

    Every day, the human heart beats about 104,000 times, pumping over 8,000 liters of blood through the body! Because it requires so much energy to perform efficiently, the experts at Source Naturals included specialty nutrients in HEART SCIENCE such as Coenzyme Q10 and L-Carnitine — integral factors in the body’s energy production cycles — to enhance the body’s energy supply.

    There are three main interconnected energy generating cycles in our cells — the Glycolytic (sugar-burning) cycle, the Krebs’ (citric acid) cycle, and the Electron Transport Chain. Together they supply about 90 to 95% of our body’s entire energy supply, using fats, sugars, and amino acids as fuel. Coenzyme Q10 is one of the non-vitamin nutrients needed to maximally convert food into ATP (the energy producing molecule). It is the vital connecting link for three of the four main enzyme complexes in the Electron Transport Chain, the next step in energy generation after the Krebs’ cycle. Using the raw materials generated by the Krebs’ cycle, the Electron Transport Chain produces most of the body’s total energy! The heart is one of the bodily organs which contains the highest levels of CoQ10, precisely because it needs so much energy to function efficiently.

    CoQ10 is one of the most promising nutrients for the heart under investigation today. It has been postulated that as a result of its participation in energy production, CoQ10 improves heart muscle metabolism and the electrical functioning of the heart by enhancing its pumping capacity.8 Many factors such as a high fat diet, lack of exercise, and cigarette smoking can lead to suboptimal functioning of the heart, and therefore failure of the heart to maintain adequate circulation of blood. Interestingly, people whose lifestyles reflect the above factors also tend to have depleted levels of CoQ10 in the heart muscle.10

    Researchers suggest taking between 10-100 mg per day of CoQ10;18,29 HEART SCIENCE provides an impressive 60 mg of CoQ10 per 6 tablets. Similar to CoQ10, L-Carnitine is important for energy production in heart cells. It is a natural amino acid-like substance which plays a key role in transporting fatty acids, the heart’s main source of energy, to the mitochondria, the “power plants” of each cell, where they are utilized for the production of ATP. Heart and skeletal muscles are particularly vulnerable to L-Carnitine deficiency. Studies have shown that supplementation with LCarnitine improves exercise tolerance in individuals with suboptimal heart and circulatory function, and seems to lower blood lipid status and increase HDL (good) cholesterol.16, 22 Each daily dose of HEART SCIENCE contains 500 mg of this extremely important compound.

    Like CoQ10 and L-Carnitine, B Vitamins help improve the ability of the heart muscle to function optimally. Each B Vitamin, after being converted to its active coenzyme form, acts as a catalytic “spark plug” for the body’s production of energy. Vitamin B-1, for example, is converted to Cocarboxylase, which serves as a critical link between the Glycolytic and Krebs’ Cycles, and also participates in the conversion of amino acids into energy. A deficiency of B coenzymes within contracting muscle cells can lead to a weakened pumping of the heart.21

    HEART SCIENCE is formulated with high quantities of the most absorbable forms of B Vitamins providing maximum nutrition for the high energy demands of heart cells.

    Homocysteine Regulators

    B Vitamins also play a crucial role in the conversion of homocysteine, a group of potentially harmful amino acids produced by the body, to methionine, another more beneficial amino acid. While it is normal for the body to produce some homocysteine, even a small elevation in homocysteine levels can have negative implications. It is well documented that individuals who are genetically predisposed to having elevated homocysteine levels (homocysteinemics) tend to have excessive plaque accumulation in the arteries and premature damage to endothelial cells (cells lining the blood vessels and heart).26 Researchers have found that even those without this genetic abnormality, whose homocysteine levels are much lower than those of homocysteinemics, still have an increased risk for premature endothelial damage and the development of plaque in the arteries.24, 26 One study conducted among normal men and women found that those with the highest levels of homocysteine were twice as likely to have clogged arteries as were those with the lowest levels.24 Furthermore, it was found that the lower the research subjects’ blood levels of folate and B-6, the higher their homocysteine levels.24 Another study found that Folic Acid administered to normal men and women who were not even deficient in folate caused a significant reduction in plasma concentrations of homocysteine!3 In order to regulate homocysteine levels, it is critical to provide the body with sufficient amounts of B-6, B-12, and Folate, whether through the diet or through supplementation. HEART SCIENCE includes high levels of these three nutrients, providing B-6 in the regular and coenzyme form for maximum utilization.

    The Dangers of Oxidized LDL Cholesterol

    While many people have heard that high cholesterol levels may negatively affect normal heart function, few people understand exactly what cholesterol is, or how it can become harmful. Cholesterol is a white, waxy substance produced in the liver by all animals, and used for a variety of necessary activities in the body. Your liver also manufactures two main kinds of carrier molecules which transport cholesterol throughout the system: Low Density Lipoprotein (LDL) and High Density Lipoprotein (HDL). Cholesterol is either carried out by LDL from the liver to all tissues in the body where it is deposited, or carried back by HDLs which remove cholesterol deposits from the arteries and carry them to the liver for disposal. Because of this, LDL cholesterol is considered damaging, while HDL is considered protective. Problems occur when there is too much LDL cholesterol in the body and not enough HDL.

    When the body becomes overloaded with fat, an over-abundance of LDL particles are manufactured to process it, and they in turn become elevated in the body to a degree that the liver cannot handle. Rich in fatty acids and cholesterol, these particles are highly susceptible to free radical attack (oxidation). Once oxidized, LDL particles are no longer recognized by the body, which attacks them with immune cells. Immune cells which are bloated by oxidized lipids (called foam cells) are a key factor in the development of “fatty streaks” — the first sign of excess arterial fat accumulation. The bloated immune cells accumulate in artery lesions and create plaque in blood vessels, leading to obstruction and constriction of the vessels. Plus, these lodged foam cells continue to secrete free radicals into the bloodstream, making the problem worse.

    The development of lesions in the arteries is not an uncommon problem. Arterial (and all blood vessel) walls are composed of a chemical matrix which holds the endothelial cells in place. That endothelial layer is the first and most important line of defense in preventing large molecules, such as cholesterol and fat, from entering the vessel wall. This matrix is composed of proteins, collagen, elastin, and glycosaminoglycans (amino sugars). Arterial lesions can be caused by suboptimal collagen and elastin synthesis due to three factors: 1. Vitamin C deficiency (since Vitamin C is a key building block for collagen and elastin); 2. excessive consumption of rancid fats, or heavy usage of alcohol or cigarettes; and 3. free radical damage. Once these lesions are created, the body attempts to repair them by depositing LDL cholesterol — similar to the way one would patch a tire. If that cholesterol is not oxidized, i.e. chemically changed to a harmful, unstable molecule, then this process does not create a problem. But when arterial lesions are “patched” with foam cells, arterial walls suffer page 3 page 4 even more damage, because those foam cells release free radicals which can further damage cell membranes.

    Unfortunately, most people have a lot of oxidized cholesterol floating through the bloodstream. The typical American diet, with its low antioxidant intake and overconsumption of fried and overcooked foods, contributes to the overall levels of harmful oxidized cholesterol. In fact, the average American intake of antioxidants is low even by USRDA standards, making Americans particularly prone to having high levels of oxidized cholesterol.

    Cholesterol Fighters

    Fortunately, there are concrete steps you can take to prevent the oxidation of cholesterol, and its subsequent ill effects on health. In addition to cutting out high-cholesterol and fatty foods, supplementation can protect existing cholesterol and all tissue cells — from oxidation. Antioxidants, substances which scavenge and neutralize free radicals, protect the cardiovascular system by halting the oxidation of cholesterol, and helping to prevent plaque accumulation in the arteries and the continual secretion of free radicals by foam cells. Supplementing the diet with high amounts of Vitamin C, a key antioxidant, also encourages a more healthy “patching” of existing lesions by using collagen (made from Vitamin C) instead of cholesterol. HEART SCIENCE contains generous amounts of the following antioxidants for their protective benefits:

  • • Beta Carotene, a plant pigment, is the naturally occurring precursor to Vitamin A. When the body takes in high enough amounts of Beta Carotene, this lipid-soluble free radical scavenger concentrates in circulating lipoproteins and atherosclerotic plaques, where it performs its antioxidant functions. Beta Carotene is particularly unique and powerful as an antioxidant because it is capable of trapping a very toxic form of di-oxygen, called singlet oxygen, which can result in severe tissue damage. Beta Carotene is one of the most efficient quenchers of singlet oxygen thus far discovered. Six tablets of HEART SCIENCE provide an unprecedented 45,000 IU of Beta Carotene!
  • • Vitamin C is found in plasma, the watery component of blood, where it functions as a potent antioxidant. In addition to strengthening artery linings through collagen manufacture, Vitamin C is involved in the regeneration of Vitamin E within LDL particles. Vitamin C also plays an important role in the conversion of cholesterol into bile acids by the liver, a crucial step in reducing blood cholesterol levels. Once converted into bile acids, and then into bile salts, cholesterol can be excreted from the body, preventing build-up. Supplementation with Vitamin C may lower levels of LDL cholesterol and increase those of HDL cholesterol.25 It may also have a part in actually removing cholesterol deposits from artery walls — good news for people who are already experiencing plaque buildup.25 Each daily dose of HEART SCIENCE provides 1,500 mg of Vitamin C in its bioactive mineral ascorbate form.
  • • Vitamin E, together with Beta Carotene, protects lipids from free radical attack. It is the major antioxidant vitamin that is carried in the lipid fraction of the LDL particle, where it protects the LDL particle from damaging oxidation. Within an LDL particle, one molecule of Vitamin E has the ability to protect about 200 molecules of polyunsaturated fatty acids from free radical damage! Vitamin E also aids in protecting the heart by interfering with the abnormal clumping of blood cell fragments, called platelets, within blood vessels.4 It has been shown to inhibit the formation of thromboxanes and increase the production of prostacyclins, which together decrease abnormal platelet aggregation.11 A high potency of Vitamin E — 400 IU’s — is included in six tablets of HEART SCIENCE in the natural d-alpha succinate form, recognized by scientific researchers to be the most absorbable form!
  • • Selenium is an important mineral which has only recently gained attention. When incorporated into the enzyme Glutathione Peroxidase, it has highly powerful free radical-scavenging abilities, and has been shown to work synergistically with Vitamins A, C, and E. An essential mineral, Selenium used to be derived from eating foods grown in Selenium-rich soil. However, modern agricultural practices have depleted soil of its natural Selenium content, leaving many Americans deficient in this vital nutrient. Several epidemiological studies show that the incidence of advanced fatty deposits in blood vessels is much greater in individuals living in geographic areas of the United States and other parts of the world where the Selenium content of the soil is very low.27
  • Proanthodyn,™ an extract of grape seeds, is being called the most powerful antioxidant yet discovered. This highly potent, water-soluble bioflavonoid contains between 93-95% proanthocyanidins, the highest concentration of any nutrient available today. The protective actions of proanthocyanidins may help to prevent the development of plaque in artery walls by inhibiting the free radicals which are produced during the oxidation of cholesterol. The optimal daily amount (100 mg) of Proanthodyn is included in six tablets of HEART SCIENCE. In addition to the protective actions of antioxidants, several other nutrients can contribute to healthier cholesterol ratios.
  • • Chromium is a trace mineral which functions to aid the entrance of glucose into cells. Six tablets of HEART SCIENCE provide 300 mcg of Chromium in the form of Chromate® Chromium Polynicotinate and Chromium Picolinate — the most bioactive forms of Chromium. Not many people are familiar with the vital role Copper plays in the body. This trace mineral is found in all tissues of the body, and is particularly concentrated in the heart. Copper is part of several enzymes, and, in this capacity, is necessary for the development and maintenance of the cardiovascular system, including the heart, arteries, and other blood vessels. Because of its role in elastin production, Copper deficiency can severely damage blood vessels and heart tissue. In fact, researchers have found an inverse relationship between Copper status and increased risk for heart damage.10
  • • L-Proline and L-Lysine are two natural amino acids which show exciting promise in helping to prevent fatty deposits in blood vessels. Researchers have recently identified a particle associated with LDL called apoprotein (a) which is believed to be a main culprit in plaque development. 17 Scientific investigation has revealed that the lipoprotein (a) particle has an adhesive quality that makes the lipoprotein fat globule stick inside blood vessels. The sticky fat globules accumulate, leading to fatty deposits in blood vessels and the subsequent clogging of the arteries. L-Proline and L-Lysine tend to form a barrierlike layer around the apoprotein (a) particle, helping to push it away from the blood vessel wall, and impeding deposit.21

    The Regulating Trio

    Three nutrients — Magnesium, Potassium, and Taurine — work closely together in the body to help maintain the normal electrical rhythm of the heart, promote proper fluid balance, and prevent excessive Calcium levels from building up in the heart and artery linings.

  • • Magnesium is one of the single most important nutrients for maintaining a healthy heart. It plays an extremely vital role in maintaining the electrical and physical integrity of the heart muscle. It has been well established that Magnesium deficiency predisposes humans to serious disruptions of normal cardiac rhythm. One theory is that because Magnesium has a relaxing effect on muscle tissue, inadequate Magnesium stores may make the coronary arteries more susceptible to muscle spasm.10 Too little Magnesium can cause a Calcium/Magnesium imbalance, which can lead to the influx of too much Calcium into heart cells, and potentiate spasms in heart tissue. Another point for consideration is that because it relaxes the blood vessels, Magnesium keeps these vessels open, allowing for maximum blood flow to the heart. Magnesium also has the unique ability to stop unnecessary blood clotting by helping to reduce platelet adhesion.31 Blood clots are naturally produced by the body as a protective device to stop excessive blood flow when the body is injured. The clotting response happens when the body senses that the normally smooth blood vessel linings are rough, indicating that there is a cut. However, sometimes the body mistakes the rough surface of plaque-covered arteries as cuts, and creates unnecessary blood clots. Or, if a high fat meal has just been eaten, tiny fat globules called chylomicrons enter the bloodstream and can cause platelets to become abnormally sticky, possibly creating clots. When these clots flow through the bloodstream and reach a part of the artery which has plaque buildup, normal blood flow is blocked, and the amount of blood which reaches the heart is severely compromised. Magnesium is also crucial for the entrance of Potassium — a key mineral for many bodily functions — into the cells. Even if the body’s Potassium stores are high, without enough Magnesium, the Potassium will not be able to enter the cells and be utilized by the body. 300 mg of Magnesium (75% of the U.S.RDA) are contained in each daily dose of HEART SCIENCE. Along with Magnesium, Potassium helps to regulate normal heartbeat and blood pressure, and is necessary for the contraction and relaxation of muscle tissue. Potassium and Sodium are present in all body fluids; Potassium is found primarily within cell fluids, while Sodium is usually present in fluids surrounding cells. Together, they function to maintain the normal balance and distribution of fluids throughout the body. The body ideally should have a Potassium/Sodium balance of about 1:1; however, because the body holds onto Sodium, yet eliminates Potassium quickly, it is important that the dietary ratio of these two minerals be at least 3:1. Unfortunately, the typical American diet, with its emphasis on processed, salty (Sodiumrich) foods and lack of fresh fruits and vegetables, severely alters the body’s natural Potassium/ Sodium balance. Diets in the United States are extremely high in Sodium — sometimes containing as much as 15 times the recommended daily intake! A high Sodium/low Potassium diet interferes with the normal regulation of heartbeat and blood pressure, and has been linked with elevated blood pressure.25 Taurine is an amino acid which helps normalize electrical and mechanical activity of the heart muscle by regulating Potassium flux in and out of the heart muscle cells.

    Artery Lining Protectors

    Your arteries form an integral part of your cardiovascular system, carrying blood away from the heart to nourish other parts of the body. In a healthy heart, blood surges through the arteries with every beat of the heart. The arteries expand with each pulse to accommodate the flow of blood. When arteries become hardened and narrowed by the build-up of plaque, they can’t expand and are not able to transport blood efficiently throughout the body. This inability to open up increases blood pressure, putting a strain on the heart as well as the arteries. HEART SCIENCE includes ingredients specifically geared to protect against plaque formation within arteries and maintain the flexibility of these vital blood vessels. N-Acetyl Glucosamine (NAG) is a key amino sugar which forms the building blocks of mucopolysaccharides. Mucopolysaccharides, which are long chain sugars, are an integral component of connective tissue. They combine to form gel-like matrixes which are present throughout tissues in the body, helping to maintain the elasticity of blood vessels which must continually adapt to the changing pressures of blood flow. Each daily dose of HEART SCIENCE provides 500 mg — a substantial amount — of this vital tissue building block. There is evidence indicating that Silicon, a natural mineral, may protect against plaque formation in the arteries. Silicon is found mainly in connective tissues, where it helps bind the body’s chemical matrix. Bound Silicon is found in high amounts in arterial walls. Researchers have found that there is a steady decline in the Silicon content of the aorta and other arteries as we age. This may be due to the low fiber content of the typical American diet, since fiber is a key dietary source of Silicon.23 HEART SCIENCE includes 400 mg of Horsetail herb extract, a natural source of Silicon. Hawthorn Berry is without question the herb most widely used to encourage normal heart function. The beneficial actions of Hawthorn Berry on cardiac function have been repeatedly demonstrated in experimental studies. Supplementation with Hawthorn Berry has been shown to improve both the blood supply to the heart by dilating coronary vessels, and the metabolic processes in the heart, resulting in normal, strong contractions of the heart muscle.34 Also, Hawthorn may inhibit the angiotensen converting enzyme, which is responsible for converting angiotensen I to angiotensen II, a powerful constrictor of blood vessels.34 Bromelain, a natural enzyme derived from pineapples, has become well-known for its neuromuscular relaxing properties. Researchers have reported favorable results when using Bromelain for soothing vascular linings. Initial research also indicates that Bromelain may break down fibrin, the glue which holds platelets together to form blood clots.6

    Capillary Strengtheners

    Capillaries are the smallest, yet some of the most important, blood vessels. If you think of your cardiovascular system as a series of roads which transport blood and oxygen, then your arteries are akin to interstate highways, your arterioles are the main city boulevards, and your capillaries are local residential streets. Capillaries are so small, in fact, that single red blood cells actually have to fold up to fit through them. Because of their tiny size and the intricate nature of their network throughout the body, capillaries are responsible for actually nourishing each individual tissue cell! Along the length of the capillaries are small openings called slit pores through which oxygen, glucose, and nutrients leave the capillaries and enter the surrounding interstitial fluid. From there, they cross cell membranes and nourish the cells. Similarly, the waste products of cells enter the fluid and cross over into the capillaries, where they are then transported to the liver and kidneys for disposal. If the capillary slit pores are torn or have lesions, then blood proteins and Sodium will leak out and cause the interstitial fluid to take on a more gel-like nature. This makes the transfer of oxygen and nutrients to the cells more difficult, as well as the disposal of cell waste products, turning the fluid into a stagnant swamp instead of a flowing river. In addition to its powerful antioxidant actions, Proanthodyn also helps protect collagen and elastin, the main constituents of tissue in the capillaries, and throughout the body. It is absolutely essential for capillary walls — which are only one cell thick — to be strong and stable, so that they do not allow blood proteins to leak into the interstitial fluid. Once the interstitial fluid takes on a gel-like consistency, the surrounding cells literally become starved from lack of nutrition. The exciting news is that the proanthocyanidins contained in Proanthodyn are among the few substances yet discovered which can help strengthen capillary walls, ensuring the liquid nature of the interstitial fluid.2 Plus, proanthocyanidins help keep capillary and artery walls flexible, allowing for proper blood flow to the heart.

    Heart Smarts

    The 1990’s mark a decade of increased awareness among Americans of important health issues. Much of the discussion has revolved around protecting that precious center of life we call the heart. Simple lifestyle change is one of the most effective ways to maintain and protect the functioning of the cardiovascular system. In order to take a holistic approach to heart care, make sure you include plenty of fresh fruits and vegetables (organic, if possible) in your diet, and cut down on fatty and cholesterol-forming foods. Reduce your salt and alcohol intake to a minimum. Try to get regular, sustained aerobic exercise for at least 30 minutes three times a week. Don’t smoke – or if you do smoke, try to eat even more fresh fruits and antioxidant-rich vegetables to counter the amount of free radicals being produced in your body. Lastly, consider adding Source Naturals HEART SCIENCE to your health regimen. HEART SCIENCE, the most comprehensive formula of its kind, provides targeted protection to the entire cardiovascular system. By approaching the promotion of normal heart function on five different levels — through the inclusion of ingredients which supply energy, decrease harmful homocysteine levels, fight cholesterol build-up, help regulate electrical rhythm, and protect artery and capillary linings — HEART SCIENCE is the perfect addition to a holistic approach to heart care.

    Source Naturals HEART SCIENCE™


    The Five Tiered Approach to Heart Health
    Six tablets contain:
    Vitamins and Minerals %USRDA
    Pro-Vit A (Beta Carotene) 45,000 IU 900%
    Vit B1 (Thiamine) 50 mg 3333%
    Vit B3 (Inositol Hexanicotinate) 500 mg 2500%
    Vit B6 (Pyridoxine HCl) 25 mg 1250%
    Coenzyme B6 (Pyridoxal-5-Phosphate)
    25 mg yielding: 16.9 mg of Vit B6 845% (Total Vitamin B6 Activity) (41.9 mg) (2095%)
    Vit B12 (Cyanocobalamin) 500 mcg 8333%
    Folic Acid 800 mcg 200%
    Vit C (Magnesium Ascorbate) 1500 mg 2500%
    Vit E (d-alpha Tocopheryl Succinate) 400 IU 1333%
    Chromium (ChromeMate® †Polynicotinate-150 mcg & Chromium Picolinate††-150 mcg) 300 mcg *
    Copper (Sebacate) 750 mcg 37.5%
    Magnesium (Ascorbate, Taurinate & Oxide) 300 mg 75%
    Potassium (Citrate) 99 mg *
    Selenium (L-Selenomethionine) 200 mcg *
    Silicon (From 400 mg of Horsetail Extract) 13mg *
    * U.S. RDA not established.
    Other Ingredients and Herbs
    Coenzyme Q10 (Ubiquinone) 60 mg
    L-Carnitine (L-Tartrate) 500 mg
    Hawthorn Berry Extract 400 mg
    Proanthodyn™ (Yielding 95 mg of Proanthocyanidins from grape seed extract) 100 mg
    L-Proline 500 mg
    L-Lysine (HCl) 500 mg
    NAG™ (N-Acetyl Glucosamine) 500 mg
    Bromelain (2000 G.D.U. per gram) 1200 G.D.U.
    Taurine (Magnesium Taurinate) 500 mg
    Horsetail Extract (Yielding 31 mg of Silica) 400 mg
    Inositol (Hexanicotinate) 50 mg

    Reference:
    1. Azuma, J., Sawamura, A., & Awata, N. (1992, Jan). “Usefulness of Taurine... and its Prospective Application.” Japanese Circulation Journal, 56(1), 95-9.
    2. Blazso, G and Gabor, M. (1980). “Odema-inhibiting Effect of Procyanidin.” Acta Physiologica Academiae ScientiarumHungaricae, 56(2), 235-240.
    3. Brattstrom, E. L, Hultberg, L. B., & Hardebo, E. J. (1985, Nov.). “Folic Acid Responsive Postmenopausal Homocysteinemia.” Metabolism, (34)11, 1073-1077.
    4. Colette, C., et al., (1988). “Platelet Function in Type I Diabetes: Effects of Supplementation with Large Doses of Vitamin E.” American Journal of Clinical Nutrition, 47, 256-61.
    5. England, M. R., et al. (1992, Nov. 4). “Magnesium Administration and Dysrhythmias...A Placebo-controlled, Double-blind, Randomized Trial.” Journal of the American Medical Association, 268(17), 2395-402.
    6. Felton, G. E. (1980, Nov.). “Fibrinolytic and Antithrombotic Action of Bromelain...” Medical Hypotheses (11)6, 1123-33.
    7. Grundy, S. M. (1993, Apr.). “Oxidized LDL and Atherogenesis: Relation to Risk Factors...” Clinical Cardiology, 16 (4 Suppl.I), I3-5.
    8. Hano, O. et al. (1994, June). “Coenzyme Q10 Enhances Cardiac Functional and Metabolic Recovery and Reduces Ca2+ Overload during Postischemic Reperfusion.” American Journal of Physiology, 266(6 Pt 2), H2174-81.
    9. Heineke, et al. (1972). “Effect of Bromelain (Ananase) on Human Platelet Aggregation.” Experientia V. 23, 844-45.
    10. Hendler, S. S. (1991). The Doctors’ Vitamin and Mineral Encyclopedia. NewYork: Fireside.
    11. Jandak, et al. (1988, Dec. 15). “Reduction of Platelet Adhesiveness by Vitamin E Supplementation in Humans.” Thrombosis Research 49(4), 393-404.
    12. Jialal, I., et al. (1991, Oct. 15). “Beta-Carotene Inhibits the Oxidative Modification of Low-density Lipoprotein.” Biochimica et Biophysica Acta, 1086(1), 134-8.
    13. Jialal, I. & Fuller, C. J. (1993, Apr. 16). “Oxidized LDL and Antioxidants.” Clinical Cardiology, Vol. 16 (Suppl. I), I6-9.
    14. Jialal, I., & Grundy, S.M. (1991, Feb.). “Preservation of the Endogenous Antioxidants in Low Density Lipoprotein...” Journal of Clinical Investigation, 87(2), 597-601.
    15. Kamikawa, T., et al. (1985). “Effects of Coenzyme Q10 on Exercise Tolerance...” American Journal of Cardiology, 56, 247-251.
    16. Kosolcharoen, P., et al. (1981, Nov.). “Improved Exercise Tolerance after Administration of Carnitine.” Current Therapeutic Research, 753-764.
    17. Lawn, R. (1992, June). “Lipoprotein (a) in ...” Medicine, 12-18.
    18. Mortensen, S.A.et al. (1985). “Long-term coenzyme Q10 therapy: A major advance in the management of resistant myocardial failure.” Drugs Exp. Clin. Res., 11(8), 581-93.
    19. Nayler, W. G. (1980). “The Use of Coenzyme Q10 to Protect Ischemic Heart Muscle.” In: Yamamura Y., Folkners K., Ito Y., eds. Biomedical and Clinical Aspects of Coenzyme Q, Vol. 2, Amsterdam: Elsevier/North-Holland Biochemical Press, 409-425.
    20. Press, R.I., & Geller, J., (1990, Jan.). “The Effect of Chromium Picolinate on Serum Cholesterol and Apolipoprotein Fractions in Human Subjects.” Western Journal of Medicine, 152, 41-45.
    21. Rath, M. (1993). Eradicating Heart Disease. San Francisco: Health Now.
    22. Rossi, C. S., & Silliprandi, N. (1982, Feb.). “Effect of Carnitine on Serum HDL Cholesterol: Report of Two Cases.” Johns Hopkins Medical Journal, 150(2), 51-4.
    23. Schwarz, K. (1977, Feb. 2). “Silicon, Fibre, and Atherosclerosis.” The Lancet, 454-456.
    24. Selhub, J., et al. (1995, Feb. 2). “Association Between Plasma Homocysteine Concentrations and Extracranial Carotid-artery Stenosis.” New England Journal of Medicine, 332(5), 286-291.
    25. Somer, Elizabeth. (1992). The Essential Guide to Vitamins and Minerals. New York: Health Media of America.
    26. Stampfer, M. J., et al. (1992, Aug. 19). “A Prospective Study of Plasma Homocyst(e)ine...” Journal of the American Medical Association, 268(7), 877-881.
    27. Suadicani, P., Hein, H. O., & Gyntelberg, F. (1992, Sept.). “Serum Selenium Concentration...in a Prospective Cohort Study of 3000 Males.” Atherosclerosis, 96(1), 33-42.
    28. Thomas, C. L. (Eds.). (1985). Taber’s Cyclopedic Medical Dictionary, (15th ed.). Philadelphia: F.A. Davis Company.
    29. Tsuyusaki, T. et al. “Mechanocardiography of ischemic or hypertensive heart failure,” in Yamaura Y et al., Biomed. & Clin. Aspects of Coenzyme Q.2 Amsterdam, Elsevier/North Holland Biomedical Press, 1980, 273-88.
    30. Verlangieri, A. J., & Stevens, J. W. (1979). “L-Ascorbic Acid: Effects on Aortic Glycosaminoglycan S Incorporation...” Blood Vessels, 16(4), 177-185.
    31. Werbach, M. R. (1987). Nutritional Influences on Illness: A Sourcebook of Clinical Research. New Canaan: Keats Publishing, Inc.
    32. White, R.R., et al. (1988, Jul-Aug.). “Bioavailability of 125I Bromelain after Oral Administration to Rats.” Biopharmaceutics and Drug Disposition, 9(4), 397-403.
    33. Whitney, E. N., Hamilton, Nunnelly, E. M. (1984). Understanding Nutrition, (3rd ed.). St. Paul: West Publishing Company.
    34. Willard, Terry, Ph.D. (1992). Textbook of Advanced Herbology. Calgary, Alberta, Canada: Wild Rose College of Natural Healing.
    35. Xiang, H., Heyliger, et al. (1988, Nov.). “Effect of Myo-inositol and T3 on Myocardial Lipids and Cardiac Function in Streptozocin-induced Diabetic Rats.” Diabetes, 37(11), 1542-8.



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    Cholestrex - Lower Cholesterol with Source Naturals Supplements
    TopPreviousNext

    Date: June 01, 2005 10:41 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Cholestrex - Lower Cholesterol with Source Naturals Supplements

    Cholestrex

    Our lives depend on an uninterrupted flow of blood throughout the 60,000 miles of arteries, veins, and capillaries that bring vital nourishment to our cells. Our bodies have complex chemical strategies to maintain and repair blood vessel walls. Cholesterol is an important part of the process. However, too much cholesterol in the bloodstream can have serious consequences for our well-being. By understanding how nutrition affects blood cholesterol, we can gain valuable control of our health. Source Naturals CHOLESTREX has been formulated to provide the nutritional support that we need to maintain healthy cholesterol levels.

    SINCE DOCTORS FIRST DISCOVERED that cholesterol was the primary ingredient in the sticky deposits that clogged their patients’ arteries, scientists have gained a thorough understanding of cholesterol’s role in our health. Essential to human and animal life, cholesterol is part of every cell in the body. Because cholesterol is so important, the liver synthesizes from 1 to 2 grams of it each day. In addition, we get about another 500 mg from the foods we eat. Problems occur when too much cholesterol gets into the bloodstream. Today, it’s estimated that over 50 million adults in the United States have cholesterol levels that are too high. The body’s processes to manage excess cholesterol depend upon a lifestyle that includes exercise, stress reduction and proper nutrition. Source Naturals Cholestrex is designed to deliver a comprehensive combination of nutrients known to support a healthy blood vessel system – and keep the life stream flowing.

    The nutrients in CHOLESTREX are known to support a healthy blood vessel system

    Cholesterol: What It Is Cholesterol is a solid waxy substance, technically classed as a “sterol.” Cholesterol enables our cell membranes to maintain their integrity. It is the basic raw material from which the body makes steroid hormones, which include the sex hormones. Cholesterol is the primary component of bile salts that the liver creates to help us assimilate fats, fat-soluble vitamins and essential fatty acids. The liver also uses bile to rid itself of stored toxins. Our skin contains large amounts of cholesterol, making it resistant to the absorption of water-soluble toxins. Even the brain is 7% cholesterol (dry weight).

    Blood vessel walls cover a surface area of half an acre and are under constant pressure

    Cholesterol in the Blood

    Because it’s not water-soluble, cholesterol must be attached to a carrier molecule in order to be transported in the bloodstream. The liver manufactures two types of carrier molecules for cholesterol, LDL and HDL. LDL (low density lipoprotein) molecules carry cholesterol from the liver out to cells of the body. One of its functions is to repair damaged cells, including those of the artery walls. LDL is primarily made up of saturated fats, (meat fats, butter, etc.). HDL (high density lipoprotein) molecules transport cholesterol and fatty acids from body tissues back to the liver for disposal. HDL helps remove excess fat and cholesterol from the bloodstream. HDL is composed of liquid fats (most vegetable oils). It’s crucial to have a proper balance between LDL and HDL cholesterol. High LDL – a sign that the body has too much fat – is a threat to the health of blood vessels, because excess LDL cholesterol may accumulate in damaged areas of vessel walls. These “fatty streaks” are the beginning stage of artery blockage.

    The oxidation of LDL cholestrol is at the heart of the problem

    Cholesterol and Artery Damage

    The walls of the blood vessels cover a surface area of half an acre and are under constant pressure. Of all the blood vessels in the body, the coronary arteries are under the greatest stress. Named for the Latin word for crown (corona), they sit directly on the heart muscle and must continually expand and contract with every heartbeat. That’s 100,000 times each day. This constant squeezing can cause small lesions in the artery wall. This triggers a repair process where LDL cholesterol comes in to patch up the damage. Recent research has found that the crux of the problem is the oxidation of LDL cholesterol. Rich in fatty acids, the LDL molecule becomes permanently altered when oxidized by free radicals (overreactive molecules that steal electrons from other molecules). These rancid, oxidized LDL molecules are no longer recognized by the body, so they’re attacked by immune system cells. These immune cells become bloated with the oxidized lipids, accumulate in artery lesions and create plaque in blood vessels. Why is LDL cholesterol being oxidized? First of all, there’s too much of it in the blood, while not enough HDL. Secondly, the blood doesn’t have enough antioxidants to neutralize free radicals. The ingredients in Source Naturals Cholestrex address these specific problems in several ways. Cholestrex also provides nutrients that protect and strengthen blood vessel walls.

    In the typical American diet, 95% of the cholesterol meant for removal is reabsorbed

    Cholestrex Has It All

    Vitamin C helps maintain the health of artery walls because it’s the key building block for collagen and elastin, the primary constituents of blood vessels. Copper is required by the enzyme that weaves together the fibers of collagen and elastin into the matrix that makes vessel walls both tough and flexible. As an antioxidant, vitamin C scavenges free radicals in the blood plasma and also regenerates vitamin E within the LDL molecule. Vitamin E has a critical role as the primary protector of LDL, preventing its oxidation. One molecule of vitamin E can protect 200 molecules of polyunsaturated fatty acids from free radical damage. GTF Chromium is involved in insulin activity and the normalization of blood sugar. Excess simple sugars are converted to triglycerides, the blood fats which can accumulate in artery walls. Lecithin is a component of HDL that emulsifies excess blood fat so it can be more readily transported in the bloodstream to the liver, where it’s metabolized. Vitamin B3 (niacin) assists in the metabolism of fats, and puts an electric charge on red blood cells so they repel each other, which prevents blood clumping. The amino acid, L-Arginine, works to lower serum cholesterol and triglycerides by inhibiting fat absorption.

    Beta sitosterol neutralizes incoming dietary cholesterol

    The Body’s Cholesterol Removal System

    HDL molecules carry cholesterol from tissues throughout the body back to the liver, where it is incorporated into bile salts. These bile salts are sent to the intestines, where they combine with fiber for excretion. One problem with the typical American low fiber diet is that 95% of the bile-bound cholesterol is reabsorbed. Since this is the body’s primary pathway for ridding itself of excess cholesterol, another strategy incorporated into Cholestrex is to maximize the production of bile salts and minimize their reabsorption by increasing levels of fiber. Fiber is a key element of Cholestrex. Its four types of soluble fiber bind with bile salts that are laden with cholesterol to ensure their excretion from the body. Oat Bran & Fiber, Grapefruit Pectin, Psyllium Seed Husks and Alfalfa Seeds also absorb cholesterol from our food, thereby lowering total blood cholesterol. Alfalfa seeds are considered a blood purifier. Beta sitosterol, a plant equivalent of cholesterol, binds to sites in the intestines that would otherwise absorb cholesterol. Cholestrex provides a daily total of 300 mg of beta sitosterol which may, by itself, neutralize 200 to 300 mg of incoming dietary cholesterol by preventing its absorption. Vitamin C, among its many other vital roles, is the key factor in activating an enzyme that will increase the liver’s conversion of cholesterol into bile salts. CHOLESTREX uses bioactive mineral ascorbate forms of vitamin C that will not irritate the digestive system. Working in conjunction with the fiber in CHOLESTREX, Calcium increases HDL, while lowering total serum cholesterol.

    Cholestrex–Intelligent Nutritional Support

    Our generation is fortunate to witness the remarkable progress made by modern science in understanding the body’s complex biochemical processes. As we realize the vital connection between nutrition and cholesterol levels, we are empowered to improve our health and vitality beyond previous standards of wellness. Source Naturals CHOLESTREX. For you and the ones you love.

    Reference:
    1. Drexel, H., et al. “Lowering Plasma Cholesterol with Beta Sitosterol and Diet.” The Lancet 1 (1981): 157.
    2. Grundy, S. M., et al. “Influence of Nicotinic Acid on Metabolism of Cholesterol and Triglycerides in Man.” Journal of Lipid Research 22 (1981): 24-36.
    3. Grundy, S. M. “Oxidized LDL and Atherogenesis: Relation to Risk Factors...” Clinical Cardiology Vol. 16 (Suppl. I), April 1993: 13-15.
    4. Hendler, S. S. “The Doctors’ Vitamin and Mineral Encyclopedia.” New York: Fireside, 1991.
    5 Jialal, I., and C. J. Fuller. “Oxidized LDL and Antioxidants.” Clinical Cardiology Vol. 16 (Suppl. I), April 1993: 16-19.
    6. Kay, R. M. and A. S. Truswell. “Effect of Citrus Pectin on Blood Lipids and Fecal Steroid Excretion.” American Journal of Clinical Nutrition 30.2 (1977): 171-75.
    7. Kirby, R. W., et al. “Oat Bran Intake Selectively Lowers Serum Low Density Lipoprotein Cholesterol Concentrations of Hypercholesterolemic Men.” American Journal of Clinical Nutrition 34.5 (1981): 824-29.
    8. Malinow, M. R., et al. “Alfalfa.” American Journal of Clinical Nutrition 1979: 1810-12.
    9. Mattson, Fred H., Scott M. Grundy, and John R. Crouse. “Optimizing the Effect of Plant Sterols on Cholesterol Absorption in Man” The American Journal of Clinical Nutrition 35 (April 1982): 697-700.
    10. Railes, R. and M. J. Albrink. “Effect of Chromium Chloride Supplementation on . . . Serum Lipids Including High Density Lipoprotein of Adult Men.” American Journal of Clinical Nutrition 34 (1981): 2670-78.
    11. Turley, S. D. and J. M. Dietschy. “The Metabolism and Excretion of Cholesterol by the Liver.” in The Liver: Biology and Pathobiology, I.M. Arias, et al. Raven Press, 1988.
    12. Turley, S. D., et al. “Role of Ascorbic Acid in the Regulation of Cholesterol Metabolism and the Pathogenesis of Atherosclerosis.” Atherosclerosis 24 (1976): 1-18.



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    TopPreviousNext

    Date: May 31, 2005 04:39 PM
    Author: Darrell Miller (dm@vitanetonline.com)

    Acetyl-L-carnitine is truly a mind-body nutrient. It helps synthesize acetylcholine, the brain's principal neurotransmitter responsible for learning and memory. And it is a more bioavailable form of L-carnitine, an amino acid derivative that performs the vital function of transporting longchain fatty acids into the cellular mitochondria where they are oxidized to generate metabolic energy. Supplemental acetyl-L-carnitine supports the activity of brain cells that depend on acetylcholine. It can also reduce the metabolic waste products that damage cells over time. As one of the most important nutrients to help slow the aging process, acetyl-L-carnitine is at the heart of Source Naturals' commitment to empower people to take charge of their own health.

    Acetylcholine is the brain's principal neurochemical of thought. Neurons need it to communicate with each other, especially to create and recall memories. Acetylcholine is also involved in muscular coordination. At neuromuscular junctions throughout the body, it tells muscles when to contract. But the efficiency of cells that use acetylcholine naturally declines with age, partly because of decreased activity of the enzyme that synthesizes this neurotransmitter.

    Neurotransmitter Production

    Acetylcholine is created when the enzyme choline acetyl transferase (CAT) attaches an acetyl group to a choline molecule. CAT activity is heightened by acetyl-L-carnitine, which donates its acetyl group. Acetyl-L-carnitine is made in small amounts naturally in the body, but its production begins to decline in midlife. In well-controlled human studies, supplemental acetyl-L-carnitine slowed the progress of mental decline by notably improving attention and memory. When supplemental acetyl-L-carnitine was combined with lipoic acid (a powerful natural antioxidant), significant improvement in memory was seen in animals. Researchers said that together the two chemicals "tune up" the mitochondria, the energy-producing organelles that power all cells. Mitochondrial decay is believed to be the primary reason for age-related deterioration of cognitive function and energy levels.

    Cellular Energy and Protection

    As the active form of L-carnitine, acetyl L-carnitine efficiently transports long-chain fatty acids into the mitochondria where they are converted into ATP (adenosine triphosphate), the energy molecule. Animal studies suggest that supplemental acetyl L-carnitine has a positive effect on energy generation as well as on the structural integrity of aging mitochondria. By supporting fatty acid metabolism, acetyl L-carnitine also helps reduce lipofuscin, a metabolic waste product composed of damaged proteins and rancid fats. The brown "liver spots" on some elderly hands are composed of this aging pigment that gradually builds up in cells of the heart, liver, brain, and lens of the eye.

    Muscle Performance

    Ninety-five percent of the body's carnitine is found in muscle cells, especially in the heart where mitochondria comprise nearly 50% of a cell's volume. During prolonged exercise, muscles have a high demand for carnitine because fats can account for up to twothirds of the energy burned. L-carnitine supplements can increase exercise endurance and reduce fatigue. Acetyl L-carnitine is also a key nutrient in Source Naturals' legendary neuroceutical formulas MEGAMIND™ and HIGHER MIND™. And because acetyl L-carnitine also generates the basic energy that affects all biological and mental processes, this mind-body nutrient is one of the few nutritional compounds with such a broad range of action in maintaining youthful functioning. Source Naturals ACETYL L-CARNITINE is therefore an essential part of a smart strategy to live well, age well.

    References

    Carta A. and M. Calvani. Acetyl-L-carnitine: a drug able to slow the progress of Alzheimer's disease? Ann NY Acad Sci 1991; 640: 228-232. Hagen T.M. et al. August 4, 1998. Acetyl-L-carnitine fed to old rats partially restores mitochondrial function and ambulatory activity. Proc Natl Acad Sci USA 95(16):9562-6. Liu J. et al. February 19, 2002. Age-associated mitochondrial oxidative decay: Improvement of carnitine acetyltransferase substrate-binding affinity and activity in brain by feeding old rats acetyl-L-carnitine and/or R-alpha-lipoic acid. PNAS 99(4):1876-81. Spagnoli A.U. et al. 1991. Long-term acetyl-L-carnitine treatment in Alzheimer’s disease. Neurology. 41(11):1726-1732.



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