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  Messages 1-17 from 17 matching the search criteria.
Hematuria: What Causes Blood in Urine? Darrell Miller 7/2/17
Hypertension & Blood Lipids Darrell Miller 7/27/16
How Does Nattokinase Improve Blood Flow? Darrell Miller 7/25/15
Ubiquinol Darrell Miller 4/16/08
This sour Indian fruit can have a sweet appetite-stifling effect Darrell Miller 5/26/07
This is sour Indian fruit can have a sweet appetite stifling effect. Darrell Miller 1/13/07
Taming the Tingle – ALA helps fight nerve damage caused by diabetes…and more. Darrell Miller 11/9/06
MIGRAINE BLOCKER - Homeopathic Remedy for Headache and Migraine Relief Darrell Miller 9/30/05
The 50 Year Service Check... Darrell Miller 7/7/05
Pep Up and Go! Darrell Miller 6/14/05
Move it and Lose it! Burn off body fat! Darrell Miller 6/14/05
Nutritional Scorecard Darrell Miller 6/14/05
Hidden In Plain Sight - The spreading epidemic: Diabetes. Darrell Miller 6/12/05
Energy Vitamins Darrell Miller 6/11/05
Re: Natural Energy Production ... Darrell Miller 6/9/05
Ellagic Active - Raspberry Extract - Promotes Healthy Cells ... Darrell Miller 6/1/05
Re: Its in the Blood Darrell Miller 5/9/05



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Hematuria: What Causes Blood in Urine?
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Date: July 02, 2017 09:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Hematuria: What Causes Blood in Urine?





Hematuria is the term for having blood present in your urine. it can be caused by urinary tract infections, kidney stones, and more. Often, it is not serious, but it can be a sign of a serious problem. You should see a doctor but there are things you can do to treat the root problem. It can also be caused by a variety of things. Any person can have to deal with this issue in their lifetime regardless of age or gender.

Key Takeaways:

  • There are two main types of hematuria: microscopic (small amount of blood in the urine) and macroscopic (blood loss can be seen with the naked eye).
  • Anyone can get hematuria, but older men, women, and athletes, have a higher risk. So do people with a family history, a recent infection, or those taking certain medications.
  • There are natural treatments depending on the cause. Cranberry juice for UTIs, pumpkin seed oil for enlarged prostate, sprouted grains for kidney stones, frankincense oil for bladder cancer.

"Blood in the urine can originate at any point along the urinary tract from the kidneys to the urethra"

Read more: https://draxe.com/hematuria/

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Hypertension & Blood Lipids
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Date: July 27, 2016 03:37 PM
Author: Darrell Miller
Subject: Hypertension & Blood Lipids

Recent studies suggest that Consuming hibiscus regularly lowers hypertension (Blood pressure) by as much as 11% systolic Blood pressure and 10% decrease in diastolic pressure. 

Also, hibiscus extract has demonstrated an ability to lower triglycerides and raise HDL-C. 

There is an alternative to dangerous prescription drugs, it is called hibiscus.  Hibiscus tea and extract is a safe and effective herb to manage Blood pressure and cholesterol.


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How Does Nattokinase Improve Blood Flow?
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Date: July 25, 2015 09:07 AM
Author: Darrell Miller
Subject: How Does Nattokinase Improve Blood Flow?

An enzyme is a protein that speeds up complex biochemical reactions in the body.  Enzymes are substrate-specific catalysts that accelerate these chemical reactions by converting substrates into simpler products.  Nattokinase is an enzyme which is extracted from a traditional Japanese delicacy called Natto.  Natto is basically boiled soy beans that have been fermented using a bacterium known as Bacillus natto.  When the bacteria act on the boiled soy beans, Nattokinase is produced.  This is the only method of preparation of natto that results in the production of this enzyme.

Many people may not be fond of the nutty flavor and sour taste of natto, but this is probably one of the world’s healthiest foods.  Its potency lies in the fact that it contains Nattokinase.  Nattokinase was discovered by Dr. Hiroyuki Sumi who was searching for the ultimate natural Blood thinner and clot-buster.  If he found one, it would be a one of a kind thrombolytic agent that would help in the fight against stroke and heart attacks associated with Blood clotting.  His Eureka moment came in 1980 when he placed natto in a Petri-dish with a thrombus (Blood clot). The clot dissolved completely within 18 hours.

Blood Clot
Blood Clot

The process of Blood clotting occurs naturally when a Blood vessel is injured.  This happens to stop the bleeding; else we would bleed to death.  However, sometimes Blood clots form in the Blood vessels even when a person is not injured.  This poses a great risk as it disrupts the smooth flow of Blood.  It may block a Blood vessel and in a worst case scenario, travel to the heart and gets lodged there.  This is where the potency of Nattokinase is best applied.  As an excellent and natural clot buster, Nattokinase will dissolve existing Blood clots and even prevent them from forming in the first place.  Another overlooked problem that often results in high Blood pressure and heart disease is hyper viscosity.  This thickening of the Blood results in a sluggish Blood flow – it increases the risk of clot formation and it overworks the heart.  Nattokinase benefits helps reinforce the actions of the body’s anti-clotting agent – plasmin.  It prevents this abnormal thickening of Blood hence promoting improved Blood flow.


References:

//www.ncbi.nlm.nih.gov/pmc/articles/PMC3879341/

//www.smart-publications.com/articles/nattokinase-powerful-enzyme-prevents-heart-attack-and-stroke

Read More

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Ubiquinol
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Date: April 16, 2008 01:10 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Ubiquinol

Coenzyme Q10 is an important cofactor that is found in nearly every cell of the body. Coenzyme Q10 is naturally produced by the body as well as attained through the foods we eat or in supplement form. With out it, every cell in our body could not produce energy to function and we would die. Coenzyme Q10 has the capability to regenerate antioxidants, protecting cells and DNA from oxidative stress which naturally occurs in the body every day.

Some may say that coenzyme Q10 exists in only one form, but in fact this substance exists in at least three forms in the body naturally. These three forms are CoQ ubiquinone, CoQH ubisemiquinone and COQH2 ubiquinol all of which are metabolically active forms of coenzyme Q10.

Ubiquinone has been commercially available for more than 30 years normally consumed orally, but recently stable forms of Ubiquinol have been made available for consumption which is of great interest by many researchers. The former ubiquinone when ingested had to be reduced by an enzymatically driven conversion from ubiquinone to Ubiquinol in the digestive tract. This conversion is done by the transfer of electrons effectively reducing the coenzyme Q10 to a more usable form Ubiquinol.

Once Ubiquinol is produced the body can more easily manufacture ATP which is directly used by cells for cellular energy. In young individuals, 90 percent of coenzyme Q10 found in the Blood is in the Ubiquinol form. This being the case, the old form (ubiquinone) was less absorbable then the newer Ubiquinol that can go right to work in the body. Ubiquinol is considered the strongest lipid soluble antioxidant that is biosynthesized, providing an active defense against oxidative stress that damages, cells, proteins, lipids, and DNA.

Some scientists believe that cellular damage from free radicals cause our bodies to age. The older we get the less our bodies produce coenzyme Q10 which in its self is an antioxidant and restores other antioxidants in the body to fight the war against free radicals. Eating foods rich in antioxidants and or supplementing with antioxidants may slow the aging process.

With age, disease, and some prescription medications, the old form of coenzyme Q10 can not easily follow the process of absorption in the intestinal tract where it is reduced and shuttled through the lymphatic system into the circulatory system (Blood). This is why Ubiquinol was so highly sot after. Ubiquinol is already reduced, the preferred form coenzyme Q10 the body wants to circulate and retain.

When one ages, energy levels always drop and one tends to slow down and feel tired sooner in the day, this may be because of a drop in coenzyme Q10 in the Blood. Many recent studies suggest that the plasma Ubiquinol ratio is reduced in response to cardiovascular disease, neurodegenerative disease, cancer, fatigue and especially in type-2 diabetes. Supplementing with Ubiquinol can help restore plasma levels and boost ones energy levels and possibly slow diseases.

To sum it up, if you are over 45, suffering from a degenerative disease or cancer, feel tired and run down, or taking prescription medications, conventional coenzyme Q10 is not what you want to take to elevate plasma levels. Ubiquinol is needed because the body can not adequately produce the most abundant form of coenzyme Q10 in he Blood (Ubiquinol). So for those who want to maintain health and wellness, look for Ubiquinol in their local health food store.

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This sour Indian fruit can have a sweet appetite-stifling effect
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Date: May 26, 2007 05:44 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: This sour Indian fruit can have a sweet appetite-stifling effect

Stay satisfied with garcinia

 

This sour Indian fruit can have a sweet appetite-stifling effect.

 

It’s funny how modern science continues to support ancient systems of herbal healing. Such is the case with garcinia: the yellowish, pumpkin like fruit of the Garcinia cambogia tree, log valued in tropical Asian cooking for its sweetly acidic taste, is a traditional Indian remedy for digestive problems that is also used to make meals more filling. Today, garcinia (also known as brindleberry and Malabar tamarind) is used in natural weight-loss products based on research supporting its stomach satiating powers. Scientists also believe that garcinia helps block fat formation and regulate glucose (Blood sugar) usage vital functions in an increasingly overweight world.

 

Filling up Faster

 

One reason so many people losing the battle of the bulge is that temptations to eat – and eat – are absolutely everywhere, often as the focal points of clever and well designed advertising campaigns. (Remember the slogan “belch’a can’t eat just one”?) To make matters worse, restaurants often serve overly generous portions and experiments have shown that the more food you serve, the more people will consume. For example, Chicago moviegoers ate 45% more popcorn from large containers even when they were given stale product (Food Quality and preference 1/01).

 

The answer would seem simple – just eat less. But knowing when to say when isn’t easy. That’s where garcinia comes in, specifically an extract taken from the rind called HCA (Hydroxycitric acid). In laboratory animals HCA has upped levels of serotonin, a brain chemical that helps suppress appetite and elevate mood, which might help take the edge off the depressing and binge-eating urges that often affect would-be weight losers. At the same time HCA appears to reduce levels of another substance in the brain called neuropeptide Y, which enhances appetite (Experimental Biology meeting 4/06).

 

Garcinia gems

 

What is it: the pumpkin-like fruit of the garcinia cambogia tree; this Indian native is used in cooking and in Ayurveda, the country’s system of traditional medicine.

 

What is does: A popular ingredient in natural weight-loss aids, garcinia is being investigated for possible fat blocking and appetite-suppressing functions; it may also help regulate glucose (Blood sugar).

 

Fat Smack down

 

The fat that stubbornly clings to your frame doesn’t always start out that way. In many cases, your body actually creates fat from excess carbohydrates (such as the icing encrusted doughnut you couldn’t pass u at breakfast). If you don’t burn off those extra carbs through exercise, they are broken down into citrates that are then transformed into the building blocks of body fat. This process is controlled by an enzyme called citrate lyase; HCA interferes with this crucial enzyme, an action that inhibits fat formation. Researchers believe the body uses those extra carbs to provide more energy; this mechanism may also have the happy side effect of further checking appetite. In addition, results from a Dutch lab study indicate that garcinia may blunt sugar-induced increases in glucose, which can help forestall diabetes development.

 

Garcinia works best when teamed with out nutrients and herbs, such as chromium, green tea and forskolin. In one investigation, over weight people who stuck to a supervised diet and exercise program supplemented with a combination of HCA, chromium and another herb called Gymnema lost body weight and mass, and showed improved fat burning capacity (Nutrition Research 1/04). This modern usage mirrors Ayurveda’s ancient precepts, according to which individual remedies are generally used in combination for more effective results. Looking to get your meals more staying power? Then look for garcinia in your favorite weight loss formula. –Lisa James

 

 



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This is sour Indian fruit can have a sweet appetite stifling effect.
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Date: January 13, 2007 02:44 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: This is sour Indian fruit can have a sweet appetite stifling effect.

It’s funny how modern science continues to support ancient systems of herbal healing. Such is the case with Garcinia: The yellowish, pumpkin like fruit of the Garcinia Cambodia tree, long valued in tropical Asian cooking for its sweetly acidic taste, is a traditional Indian remedy for digestive problems that is also used to make meals more filling. Today, Garcinia (also known as brindleberry and Malabar tamarind) is used in natural weight-loss products based on research supporting its stomach satiating powers. Scientists also believe that Garcinia helps block fat formation and regulate glucose (Blood sugar) usage—vital functions in an increasingly overweight world.

Filling Up Faster

One reason so many people are losing the battle of the bulge is that temptations to eat-and eat—are absolutely everywhere, often as the focal points of clever and well designed advertising campaigns. (Remember the slogan “belch’a can’t eat just one”?) To make matters worse, restaurants often server overly generous portions and experiments have shown that the more food you serve, the more people will consume. For example, Chicago moviegoers ate 45% more popcorn from larger containers even when they were given stale product (Food Quality and Preference 1/01).

The answer would seem simple—just eat less. But knowing when to say when isn’t easy. That’s where garcinia comes in, specifically an extract taken from the rind called HCA (Hydroxycitric acid). In laboratory animals HCA has upped levels of serotonin, a brain chemical that helps suppress appetite and elevate mood, which might help take the edge off the depression and binge-eating urges that often affect would-be weight losers. At the same time HCA appears to reduce levels of another substance in the brain called neuropeptide Y, which enhances appetite (Experimental Biology meeting 4/06).

Garcinia Gems

What it is: the pumpkin-like fruit of the Garcinia cambogia tree; this Indian native is used in cooking and in Ayurveda, that country’s system of traditional medicine

What it Does: A popular ingredient in natural weight-loss aids, garcinia is being investigated for possible fat blocking and appetite suppressing functions; it may also help regulate glucose (Blood sugar).

Fat Smackdown

The fat that stubbornly clings to your frame doesn’t always start out that way. In many cases, your body actually creates fat from excess carbohydrates (such as the icing encrusted doughnut you couldn’t pass up at breakfast). If you don’t burn off those extra carbs through exercise, they are broken down into citrates that are then transformed into the building blocks of body fat. This process is controlled by an enzyme called citrate lyase; HCA interferes with this crucial enzyme, an action that inhibits fat formation. Researchers believe the body uses those extra carbs to provide more energy; this mechanism may also have the happy side effect of further checking appetite. In addition, results from a Dutch lab study indicate that garcinia may blunt sugar-induced increases in glucose, which can help forestall diabetes development.

Garcinia works best when teamed with other nutrients and herbs, such as chromium, green tea and forskolin. In one investigation, overweight people who stuck to a supervised diet and exercise program supplemented with a combination of HCA, chromium and another herb called Gymnema lost body weight as mass, and showed improved fat burning capacity (Nutrition Research 1/04). This modern usage mirrors Ayurveda’s ancient precepts, according to which individual remedies are generally used in combination for more effective results.

Looking to give your meal more staying power? Then look for garcinia in your favorite weight loss formula. –Lisa James.



--
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Taming the Tingle – ALA helps fight nerve damage caused by diabetes…and more.
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Date: November 09, 2006 01:27 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Taming the Tingle – ALA helps fight nerve damage caused by diabetes…and more.

For some people the constant tingling in their feet is the worst part. Others feel like their feet are being stabbed or burned, or that their extremities are simply lifeless. All these folks suffer from peripheral neuropathy, nerve damage that afflicts nearly 30% of people with diabetes aged 40 and older. And if the discomforting sensations are not enough, neuropathy can lead to falls, wounds that won’t heal, even amputation.

Untold numbers of individuals have been helped by alpha lipoic acid (ALA), a supplement that European practitioners have used as a standard neuropathy treatment for 30 years. ALA (also known as thioctic acid) assists in the chemical reaction that generates energy within cells. It serves as a universal antioxidant—a substance that can fight tissue-damaging free radicals in both the fatty watery parts of a cell-and helps the body create additional free radical fighters, such as glutathione. ALA can even help regenerate several other antioxidants, including coenzyme Q10 (CoQ10) and vitamins C and E.

Defying diabetes

People with diabetes need antioxidant protection as much as anyone. Fortunately for them, though, ALA fights this insidious disorder in many other ways.

Diabetes occurs when the body can no longer effectively use glucose (Blood sugar), its main energy sources; ALA helps shepherd glucose out of the Blood and into cells. It also interferes with glycosylation, a process in which glucose sticks to proteins such as the low-density lipoprotein (LDL) that carries cholesterol through the Bloodstream. That’s important because this “sticky” LDL can adhere to arterial walls, creating a major risk factor for heart disease. ALA combined with exercise appears to make insulin, the hormone that controls glucose usage, more effective. What’s more, early research indicates that ALA can deflect another cardio hazard by interfering with the ability of salt to push Blood pressure upward (molecular and Cellular Biology 12/03).

ALA Annotations – what is it? Alpha Lipoic acid, a substance the body creates naturally.

What it Does: ALA, a powerful antioxidant in its own right, plays a vital role in the creation and renewal of other antioxidants. It is used to treat peripheral neuropathy; nerve damage caused by diabetes, and is also under investigation for possible therapeutic effects in other disorders, including multiple sclerosis and age-related cognitive decline.

Diabetes doesn’t just attack the nerves and the heart—its effects are felt throughout the body. That’s why scientists are examining whether ALA can tackle other diabetic complications: in lab studies it has forestalled diabetes-related kidney and eye damage. (Check Blood-sugar levels regularly when using ALA, especially if you’re taking other glucose regulators.)

Protecting Nerves

While diabetes is one of the most common causes of nervous system damage, it isn’t the only one. In test tube studies ALA has promoted chemical reactions that encourage neurons (nerve cells) to survive and grow; as a result some scientists believe this natural antioxidant may eventually play a role in treating degenerative nerve disorders. Such research is in its beginning stages, but the results are still intriguing. For example, in mice ALA has slowed progression of a disorder that mimics multiple sclerosis in human beings (Journal of Neuroimmunology 3/04) and improved age-related memory loss when used with N-acetyl-cysteine (NAC), another antioxidant supplement (Journal of Neurochemistry 3/03). A number of other conditions that become more common with age may also benefit from ALA, including arthritis and thinning skin.

If you suffer from both diabetes and the nerve damage it causes, ask your practitioner about ALA. It just may help your feet and the rest of you feel happy. –Lisa James



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MIGRAINE BLOCKER - Homeopathic Remedy for Headache and Migraine Relief
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Date: September 30, 2005 09:41 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: MIGRAINE BLOCKER - Homeopathic Remedy for Headache and Migraine Relief

NEW PRODUCT ANNOUNCEMENT

MIGRAINE BLOCKER - Homeopathic Remedy for Headache and Migraine Relief

  • Safe and natural treatment for temporary relief of migraine headache pain, pressure and throbbing.
  • Caffeine, Aspirin, Ibuprofen, and Acetaminophen-Free
  • Fast and Gentle
  • No drowsiness

    One tablet contains:
    Ingredients: Active: Chamomilla (Chamomile) 4X, Bryonia alba (White Bryony) 6X, Iris versicolor (Blue Flag) 6X, Juglans cinerea (Butternut) 6X, Pulsatilla nigircans (Wind Flower) 6X, Sanguinaria canadensis (Blood Root) 6X, Natrum Muriaticum (Sodium Chloride) 10X, Magnesia Muriatica (Magnesium Chloride) 10X, Phosphorus (Phosphorus) 10X, Silicea (Silica) 10X, Zincum Metallicum (Zinc) 10X, Belladonna (Deadly Nightshade) 12X, Gelsemium sempervirens (Yellow Jessamine) 12X, Ignatia amara (St. Ignatius Bean) 12X, Scutellaria (Skullcap) 12X. Inactive: lactose and magnesium stearate.

    Suggested Use:
    For best results, begin taking at the first sign of symptoms. Chew tablet slightly and allow to dissolve in the mouth. Adults: Take 2 tablets initially, then 1 tablet every two hours as needed. Children: 6-12 years, use one half of the adult dosage. For children under the age of 6 years, consult with your licensed health care professional. Do not exceed 12 tablets per day.



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    The 50 Year Service Check...
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    Date: July 07, 2005 09:18 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: The 50 Year Service Check...

    Sad but true: Guys who wouldnt forget to give their cars an oil change will go years without having their own inner workings inspected. But a reluctance to have ones chassis checked at the practitioner's office can translate into serious body engine failure. While physical exams are always important, they become a nevessity with advancing age. We're not saying 50 is old, mind you--a couple at Energy Times staffers are starting the big five-oh right in the face--but it's a good time to start getting regular checkups if you haven't been in the habit. Here's some of the things to look for next time they pop your hood.

    TEETH:

    Get those choppers checked at least once a year--untreated gum disease can lead to the kind of low-level inflammation now thought to be a culprit in numerous illnesses, including heart disease.

    EYES:

    Some experts recommend yearly testing for glaucoma, a condition in which increased pressure within the eyeball can cause blindness if not treated. Presbyopia, the farsightedness that accompanies increasing age, generally starts in one's 40s; time to invest in a pair of reading glasses.

    HEART:

    Have your Blood pressure taken by a professional at least once a year. Checks for cholesterol and Blood sugar are part of a metabolic panel (Standard Blood work) to be done every three years; it should include total cholesterol, LDL "bad" cholesterol and triglycerides (Blood fats). Discuss testing for CRP (C-reative Protein), a marker of chronic inflammation, with your practitioner.

    THYROID:

    The American Thyroid Association suggests an initial check of your thyroid, a gland in your neck that serves as the body's energy transformer, at age 35 with retests every five years afterwards. If you can't seem to lose weight and/or are sonstantly tired, ask about having your thyroid hormone levels assessed.

    LIVER

    Your liver won't send out distress signals until it's pretty banged up. Since the standard metabolic panel includes the liver-enzyme check be sure to have it done every three years; that frequency may need to increase if you have a history of heavy alcohol or workplace exposure to toxins.

    Prostate:

    Having a yearly digital rectal examination (DRE) is recommended. Blood testing for prostate-specific antigen (PSA) is more contraversial.

    COLON:

    Colonoscopy, in which a lighted tube is used to view the entire colon, is the gold standard (although doctors are working on a less invasive virtual colonoscopy); once every 10 years starting at age 50 is recommended. A fecal occult Blood test (FOBT) should be preformed every year, but keep in mind it can yeild false results, positive and negative.

    Don't Forget to:

  • Create a list of all your health concerns and discuss them with your practitioner.
  • Discuss and update your medical history, including illnesses suffered by close relatives (for help, see www.ama-assn.org\go\familyhistory).
  • Be totally honest with your practitioner about habits or lifestyle choices, such as smoking or excessive alcohol use, that can affect your health.
  • Set up a screening schedule tailored to your particular needs.
  • Ask for a copy of all paper work for your personal files.
  • Note:

    Screening frequencies are for healthy individuals with no known risk factors. If you have a pre-existing condition or are at risk for one, follow your practitioner's recommendations.

    : Energy Times



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    Pep Up and Go!
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    Date: June 14, 2005 05:45 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Pep Up and Go!

    Pep Up and Go!

    by Harris Parker Energy Times, February 2, 2000

    Feel your energy flagging?

    You've lost count of the number of phone calls you fielded all afternoon-the last was from your son, who missed the late bus home from school-and colleagues needing your decision are lined up outside your office. Your husband has invited clients home for dinner. You wilt like a new hairdo on a damp August day and pray for a miracle to jump-start your engine.

    Your pep quotient depends on three essential ingredients: nutrients you consume through your diet and supplements, how much you exercise and your sleep schedule.(Of course, if you're troubled by any kind of disabling, ceaseless fatigue accompanied by mental fuzziness, joint pain, sore throat, swollen glands, headaches and other chronic distress, consult your health practitioner.)

    Vitamins and Energy

    Certain nutrients are called vitamins because scientists consider them to be crucial for vitality. They generally function as coenzymes, partnering with the enzymes that are catalysts for the chemical reactions constantly taking place in our bodies. Our need to replenish our store of vitamins, which may merge with cell, muscle, enzyme, hormone, Blood and bone structure once they have been absorbed, depends on their rate of utilization, according to The Real Vitamin & Mineral Book (Avery) by Shari Lieberman, PhD, and Nancy Bruning.

    While a low-fat diet rich in raw fruits and vegetables helps supply important nutrients, a B complex supplement and a balanced multivitamin can guarantee daily vitamin levels.

    Be Energetic with B Vitamins

    Vitamins, especially the B vitamins, play extremely important roles in producing cellular energy. The chart on page 39 lists the key vitamins and describes their effects as well as the consequences of not getting enough of them. Their benefit is felt most profoundly in the energy producing process known as the Krebs cycle (which we'll explain in a moment).

    Vitamins B2 and B3, for example, supply the major building blocks for substances that are called flavin adenine dinucleotide (FAD and FADH) and nicotinamide adenine dinucleotide (NAD and NADH), which are critical elements of energy production in the Krebs cycle as well as a process called oxidative phosphorylation.

    Hundreds of Reactions

    Even though you may never have heard of NAD and NADH, these molecules are found in very many places throughout your body; they play a role in hundreds of biochemical reactions in all kinds of cells. B vitamins also combine with other materials to build coenzymes, chemicals which help form other chemicals necessary for cellular energy. B vitamins are crucial: miss out on one or more and you may break these metabolic chains necessary for peak energy.

    Energy to Spend

    The main energy currency of every cell single cell is ATP: a chemical called adenosine triphosphate. This material is used by cells for every imaginable task including reproduction, growth, movement and metabolism. Specialized metabolic cycles within the cell are designed to generate ATP.

    Consequently, the more ATP our cells create, the more energy can be generated. The raw materials used to make cellular energy are glucose (Blood sugar) and "free" fatty acids. The best way to supply your cells with the sugar they need is to consume complex carbohydrates which also supply fiber and other nutrients. When you eat carbohydrates, they are made into glucose which is stored as a starch called glycogen in muscles and the liver. Your body can rapidly turn glycogen into glucose for extra energy. (The process of making energy from glycogen yields carbon dioxide and water as well as ATP.)

    Making Energy

    The first step in making glucose into energy is called glycolysis. This complicated process requires nine different steps. During these steps, glucose is made into a substance called pyruvate. The process of glycolysis requires ATP, but yields twice as much ATP as is present when it starts.

    From here, the process gets a little more complicated as pyruvate enters into a complex chain of events in tiny cellular structures called mitochondria. (Many metabolic events take place in the mitochondria.) The pyruvate molecules are converted to a molecule known as acetyl coenzyme A and eventually made into carbon dioxide, water and more ATP.

    This process is known as the Krebs cycle or citric acid cycle. It also involves a series of events known as oxidative phosphorylation in which NADH formed during the Krebs cycle is oxidized to form ATP.

    Why is fat such a concentrated source of energy? Free fatty acids enter the Krebs cycle to help generate ATP much more efficiently than glucose - producing roughly six times more energy per gram than glucose.

    And Don't Overlook. . . . . .other supplements that may aid energy production: • Alpha Lipoic Acid, an antioxidant that works in the fatty tissues of cell membranes and in cells' watery interiors • Coenzyme Q10, also known as ubiquinone as it exists everywhere in the body, acts like a vitamin because it stimulates some reactions. CoQ10 protects cell membranes, especially of the heart, against oxidation and toxins.

    Ginsengs: Energy Generators

    With their legendary and slightly mysterious characteristics, the ginsengs are greatly respected natural energy boosters. " Perhaps no herb has excited so much interest in medical circles as ginseng, and yet, strangely, it does not actually 'cure' any one particular ailment," reports Michael Hallowell, the author of Herbal Healing (Avery) and a frequent lecturer on botanic medicine. "Rather, its virtue lies in its tremendous power as a tonic and invigorator. Russian athletes are prescribed large amounts of ginseng because researchers in Moscow have shown that it not only improves stamina, but also increases the efficiency with which Blood is pumped to the muscles."

    What are the physiological mechanisms that allow ginseng to bolster your get up and go? In order to unravel the legend and lore of ginseng, the first step is understanding the intricacies of the three types: • Asian (Panax ginseng), which produces the strongest and most profound stimulation; • American (Panax quinquefolium), which soothes at a more subtle level; • Siberian (Eleutherococcus senticosus), a stamina booster embraced by a wide range of athletes. All three varieties are treasured for their ability to help people adjust to stress.

    Biologically Active

    The ginsengs are adaptogens, "biologically active substances found in certain herbs and plants that help the body and mind adapt to the changes and stress of life," says Stephen Fulder, MD, author of The Book of Ginseng and Other Chinese Herbs for Vitality (Inner Traditions). "Stress is not an illness in itself. Stress is change, our ability to adapt to all the changes that occur in life, emotional or physical, from exercise, work, chemicals, drugs, food, radiation, bacteria, disease, temperature, or simply too many late nights or too much fun."

    The body reacts to stress by producing the hormone adrenaline, which throws the whole body into a state of alert. Metabolism, Blood pressure and circulation accelerate; immunity and resistance drastically decline; performance suffers.

    Top-Notch Tonics

    Enter the ginsengs, with their varied, subtle tonic qualities. The Greek name for this herb, "panax," means "panacea" or cure-all. But the Chinese, who first referred to it 2,000 years ago, more literally called it "ren shen" or "person root," in reference to its physical resemblance to a miniature human form.

    " Most exhibit medicinal properties, but each species has a different chemical makeup and has a unique application in Traditional Chinese Medicine (TCM)," says Kim Derek Pritts, author of Ginseng: How to Find, Grow and Use America's Forest Gold (Stackpole). "In general, all true ginseng contains biologically active saponins (chemicals similar to human hormones), essential oils, carbohydrates, sugars, organic acids, nitrogenous substances, amino acids, peptides, vitamins and minerals."

    Building Vital Energy

    All the ginsengs strengthen, nourish and build Qi, the TCM concept describing basic vital energy circulating through our bodies. Every physical and mental function, from breathing, thinking, nutrition and circulation, is regulated by Qi. Although many of the Native American tribes used the abundant, indigenous Panax quinquefolium ginseng extensively, particularly to increase mental acuity and boost fertility, the herb never has been as popular in North America as it is in Asia. American ginseng traditionally has been a lucrative export crop to China, where the wild native variety suffers from overharvesting. Even today, according to Paul Bergner in The Healing Power of Ginseng & the Tonic Herbs (Prima), 95% of the American ginseng crop is exported to China, where XiYang Shen, or "western sea root," as it is called, is immensely valued and costs double what it does here.

    Energy Boost

    Jacques MoraMarco, author of The Complete Ginseng Handbook: A Practical Guide for Energy, Health and Longevity (Contemporary), as well as a licensed acupuncturist and doctor of Eastern medicine, suggests American ginseng for a slight energy boost. The moderate effect of American ginseng is considered a more appropriate tonic to the intensity of our pace and diet.

    Variations on a Theme

    In TCM terms, American ginseng cools and moistens, as well as lubricates and strengthens the body. It is reputed to reduce fevers and night sweats and alleviate hot, dry lung problems like smoker's cough. With its emollient qualities, American ginseng is considered to treat dry, wrinkled skin effectively.

    The Bolder Energizer

    Asian ginseng, which includes red Korean panax, is a bolder energizer taken by those who feel depleted from anemia, Blood loss, cardiovascular weakness, injury, shock or trauma, as well as the disabling effects of age. In general, Asian ginseng is warming and stimulating, urging the body to run faster.

    Siberian ginseng, though botanically not a true ginseng, still acts similarly to Asian ginseng in its reputed power to control stress, boost energy, support the immune system, enhance performance and increase longevity. Called Wu Cha Seng in Chinese, Siberian ginseng is perceived by natural practitioners as an ideal herb for the healthy who want to lift both stamina and endurance. Experts believe it counteracts the effects of cortisol, the stress hormone produced by the adrenal glands in response to injury, pain or emotional turmoil.

    Natural Energy Boosters

    The herbal pharmacopeia includes several other natural energy boosters available in various forms-shakes and bars for those on the run-loaded with nutrition absent from commercial snacks. Some choices: • Ginkgo biloba-used in Chinese medicine to heat the body and increase sexual energy. Ginkgo enthusiasts take this herb to increase the supply of oxygen to the brain and generally increase circulation. • Gotu kola-may stimulate the central nervous system and help eliminate excess fluid, thereby reducing fatigue. • Astragalus-a Chinese herb that enhances energy and builds the immune system. It is credited with strengthening digestion, improving metabolism, increasing appetite, combating diarrhea and healing sores. • Schisandra-also a Chinese herb, treats respiratory illness, insomnia and irritability and rejuvenates sexual energy. Its mild adaptogens help the body to handle stress. • Licorice-is a favored endocrine toner in Chinese medicine. It is reputed to support the adrenals, the pair of small glands directly above the kidneys that secrete steroidal hormones, norepinephrine and epinephrine, the "fight or flight" hormones. People with high Blood pressure or edema, or pregnant women, should avoid it. • Ashwagandha-an Ayurvedic herb used for thousands of years in the traditional healing of India as a potent strength builder for men and women.

    Experienced herbal practitioners acquire an impressive and fascinating store of knowledge and experience-you'll find it helpful to visit one as you begin your course of ginseng or other energy-boosting herbs.

    TCM Visitation

    When you visit a TCM practitioner, you'll notice that she evaluates your body's condition through an extremely careful examination of all the different systems: Several pulse points are felt in order to ferret out and detect troubling abnormalities. The condition and color of the tongue is observed to decipher digestive disorders. In addition, your urine may be examined to determine other imbalances and specific health problems.

    In many cases, your TCM practitioner will recommend ginseng as an adaptogen that can give you an overall boost. When taking ginseng, follow the directions on the package. Note: in some cases, you may want to consume a little bit less if you suffer headaches, insomnia or high Blood pressure. Consult your health practitioner if you are afflicted with either acute inflammatory disease or bronchitis.

    Then take comfort in the eternal soothing wisdom of Chinese Traditional Medicine. In the first century A.D., the Shen Nong Ben Cao Jing (The Divine Husbandman's Classic of the Materia Medica) effusively described ginseng and the tonic herbs in this beguiling and intriguing manner: "The first class of drugs...are considered to perform the work of sovereigns. They support human life and they resemble heaven. They are not poisonous regardless of the quality and duration of administration."



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    Move it and Lose it! Burn off body fat!
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    Date: June 14, 2005 12:04 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Move it and Lose it! Burn off body fat!

    Move it and Lose it! Burn off body fat! by Mimi Facher Energy Times, June 1, 1997

    So you're feeling a little blah, a little overweight, and you're looking to drop a few of those winter pounds gained during the colder months. Maybe you've dabbled with diets and jogged around the neighborhood a few times but you're still packing unsightly bulges. If so, you may be considering the idea of turning to supplements to help you drop those pounds. Well, two types of diet supplements now generally available, combined with a diet and exercise program, may be able to help you trim those stubborn pounds.

    The first type of supplement, called metabolic optimizers, which include ephedra, caffeine and salicin (derived from willow bark), boost your metabolic rate, causing your body to burn calories faster. The second class, lipotropic substances, aid the body in fat mobilization, causing greater utilization of stored fat. These products include chromium, carnitine and hydroxycitric acid (HCA). Both classes of supplements have been around in various forms for quite a while but are now enjoying greater popularity among dieters.

    Trying to cope with a weight problem is a dilemma expanding throughout modern society. According to a 1995 Harris poll, nearly 75% of Americans are overweight. Although it's well known that the way to lose weight is to expend more calories than you take in, supplements may be able to help you burn off extra calories.

    Thermogenesis and You

    Metabolic optimizers are supposed to aid weight loss through a process called thermogenesis. Thermogenesis is a natural process in which fat is burned to produce body heat. Fat that isn't burned is stored on the hips, thighs, stomach, etc. Thermogenic agents are designed to counteract your body's fat storage mechanisms by causing your body to maintain a higher metabolic rate-turning your internal thermostat up to burn fat faster. The thermogenic process can be jump-started by a number of factors including cold, exercise, certain dietary nutrients and metabolic optimizers.

    Ephedra

    The ephedra herb, also known as ma huang is one of nature's earliest medicines, known for over 5000 years to the Chinese, who used it to relieve allergies, coughing, wheezing and cold and flu symptoms. In the US, ephedra has been available since the 1800s.

    The ingredients in ephedra include the alkaloids ephedrine, pseudoephedrine and norephedrine. Concentrated forms of these substances are used in today's over-the-counter cold, allergy and asthma relief formulas.

    Ma huang's effectiveness as a weight loss aid is tied to its appetite suppressant and stimulant properties. By speeding up action of the thyroid gland, the ephedrine found in the herb acts a thermogenic agent, boosting the rate at which the body metabolizes fat and promoting weight loss. According to Mark Blumenthal, Executive Director of the American Botanical Council, "When used as part of a total package that includes diet modification and exercise, ma huang can be highly effective in the short run because it increases the speed of the body's metabolism and suppresses appetite."

    Because of their strong stimulant effect, ephedra and its derivatives have engendered some controversy. However, in its long history, billions of doses of ephedra have been consumed without problem. But ephedra supplements should only be used as directed on product labels. People with cardiovascular problems, diabetes, thyroid or prostate dysfunction, high Blood pressure and those taking MAO inhibitors, pregnant or nursing should avoid this herb.

    Salicin Burns Fat

    Salicin, a substance derived from willow bark-which is also the original source for aspirin, a related compound-can boost the burning of fat when combined with ephedra. An animal study in the American Journal of Clinical Nutrition found that while ephedra boosted calorie burning by almost 10%, when ephedra was combined with aspirin, extra calorie burning just about doubled. Another study in the Internatioanl Journal of Obesity showed that when overweight women took aspirin and ephedrine during a meal, their bodies burned off more calories than normal. (Eating a meal produces a thermogenic effect as your body expends energy in digestion. That's why dieters are told not to skip meals. Skipping meals lowers your metabolic rate, decreasing your calorie expenditure.)

    Similar studies also show that caffeine, the stimulant that gives coffee its eye-opening kick, can also boost ephedra's thermogenic properties. But before using these combinations check with a health practitioner knowledgeable about nutrition. Aspirin or salicin may cause stomach upset in some people (although salicin is generally tolerated well.)

    Carnitine: Lipotropic Amino Acid

    To get carnitine into your system, you don't have to take it as a supplement. Your body already makes this vitamin-like substance. However, your body doesn't make that much. And it is said to be especially low in people with heart disease.

    This non-essential amino acid (said to be non-essential because human bodies produce it) is a key ingredient in the formation of mitochondria membranes. Mitochondria are tiny structures in your cells that burn fats for energy. Consequently, sufficient carnitine is necessary for the movement of fat into the mitochondria where it is consumed. When not enough carnitine is present, the breakdown of long chain fatty acids slows down.

    Said to improve the recovery rate for athletes (it may limit the production of lactic acid, a waste product in muscle tissue), carnitine can also lower cholesterol levels, boost levels of HDL (the good cholesterol) and decrease serum triglycerides (Blood fats linked to heart disease). Not bad for a nutrient that coaxes fat into those teeny, ceullular, mitochondrial furnaces.

    Go for the Chrome

    Chromium-based supplements work as lipotropic agents by aiding insulin use in the body. This essential trace mineral is required for normal protein, fat, and carbohydrate metabolism. According to Dr. Michael Janson, author of The Vitamin Revolution in Healthcare and President of the American Preventive Medical Association (APMA), "Chromium is important for proper insulin activity. Insulin moves sugar into the muscle cells, where it is burned off as energy. Chromium improves the activity of insulin, and since insulin causes fat deposition, less of it means less fat deposition." Chromium has also been shown to build muscle tissue and to reduce LDL cholesterol, which has been linked to heart disease.

    Although the body's minimum requirement is low, the American diet tends to be deficient in chromium, in part because the mineral can be difficult for the body to absorb. The fact that, in nature, chromium is most powerfully concentrated in brewer's yeast, wheat germ and liver-items most Americans rarely eat-probably hasn't helped either. Other natural sources of chromium include whole grains, molasses and beef. But it is estimated that 50% of Americans are chromium deficient. An early study found that overweight adults taking a chromium supplement lost an average of 22% body fat, while maintaining or gaining lean body mass. In another study, athletes consuming 200 mcg. of chromium a day showed an average loss of 7.5 lbs. of body fat after six weeks, without a corresponding loss of muscle tisue. Overall, although some studies question chromium's precise effects, many experts are optimistic about this substance because of its relationship to insulin in the body's metabolism.

    Hydroxycitric Acid (HCA)

    Another possible addition to the dieter's arsenal is HCA. In nature, HCA appears chiefly in a fruit called garcinia cambogia (sometimes also called Malabar tamarind or brindall berry), a citrus plant found primarily in Asia, where the rind is often used as a flavoring agent. HCA works by inhibiting the enzyme in the body responsible for converting carbohydrates into fat. HCA causes calories to be burned in an energy cycle similar to thermogenesis and acts as somewhat of an appetite suppressant. HCA is also said to have a role in reducing triglycerides and LDL cholesterol levels.

    Several animal studies have shown that HCA caused significant weight loss without a reduction in lean body mass. In other words, the pounds that came off came out of fat stores, and not out of energy or muscle reserves. This means that HCA takes off not just weight but body fat, making it a potentially effective tool against weight regain.

    Dr. Elson Haas, director of the Preventive Medical Center of Marin in San Rafael, CA, and author of Staying Healthy With Nutrition: The Complete Guide to Diet and Nutritional Medicine, believes that HCA can be a helpful aid for dieters when used in combination with eating habit changes and exercise. He recommends an HCA and chromium blend for optimum appetite suppression. "This combination can keep the appetite down and reduce sugar cravings," he says.

    Although human research data on HCA is still in the preliminary stages, the animal study results are positive, and the supplement seems to have minimal side effects in most people.

    Some Overall Recommendations

    You are likely to lose weight faster if you eat sensibly. This means avoiding foods high in fat or sugar (which are the most likely to add to stored body fat), but it doesn't mean starving yourself. A sensible balanced diet, along with moderate exercise, is still the best prescription for weight loss. As Dr. Haas puts it, "I'm a firm believer in diet and exercise. Using supplements responsibly can help you to lose weight provided they're combined with dietary changes and exercise. They won't work if you don't change anything." No one is suggesting that dietary supplements are a miracle cure for being overweight-as always in self-health care, there are no magic wands. But, used as directed and combined with a good diet and exercise plan, you could find that these supplements might help you work your way to a slimmer you.

    Mimi Facher is a freelance writer who has contributed to Prevention, Cosmopolitan and Self.



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    Nutritional Scorecard
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    Date: June 14, 2005 10:52 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Nutritional Scorecard

    Nutritional Scorecard by Sylvia Whitefeather Energy Times, June 15, 2004

    For over 50 years, the federal government has produced Recommended Daily Allowances (RDAs) as guidelines for vitamin and mineral intake. Then, in 1993, the Reference Daily Intakes (RDIs) superseded the RDAs. By applying this new designation, the government's guidelines are now supposed to represent the designated amounts that an average person should consume. With this in mind, and the fact that many experts think you should consume more than some of the RDIs, how does your nutritional scorecard add up? Answering a few nutritional questions can point you in the right direction.

    Perfect Protein

    Are you trying to lose weight? If you are, the latest thinking on weight loss opines that eating more protein may be the key to keeping your weight down. Two recent studies published in the Annals of Internal Medicine (5/18/04) found that people who ate a low-carbohydrate, high-protein diet lost more weight and had better cholesterol levels than dieters who ate fewer fatty foods. Both studies found that a low-carb diet can improve your triglycerides (Blood fats) and boost your HDL, or good, cholesterol.

    Eating protein satisfies both tummies and taste buds. Researchers have found that the amount of protein eaten in a meal determines not only how much food you eat but also how satisfied you feel after eating (J Nutr 2004 Apr; 134(4):974S-9S). And when you feel satisfied after eating less food you improve your odds of losing weight.

    We need about 50 grams of protein a day to support the body's functions. The best sources of protein are eggs, meat, milk, protein shakes and yogurt.

    Classy Carbohydrates

    Does your energy level go up and down during the day? To get off the energy rollercoaster, cut down on carbohydrates, and make sure the carbs you do eat are complex.

    Carbohydrates have been getting some unflattering press lately. Yes, if you want to lose weight, you may want to go on a strictly low-carb diet. But for those not concerned with weight, carbohydrates are the principle source of energy for the body.

    What's more, even if you do restrict carbohydrates, you should still eat a tiny bit of them. Without some carbs in the diet your body cannot regulate protein or fat metabolism. According to Michael and Mary Eades, MD, authors of The 30-Day Low-Carb Diet Solution (Wiley), "Carbohydrates control insulin and insulin controls your metabolic health."

    So, make your carbohydrates count. Indulge in complex carbohydrates: whole grains, fruits and vegetables. In those foods, carbs are accompanied by fiber and larger amounts of vitamins and phytonutrients. Other reliable sources of complex carbohydrates are whole wheat bread, brown rice and oatmeal.

    Fabulous Fiber

    Are you concerned about your heart health? Fiber from beans, oats, legumes, nuts, rice bran, fruits and vegetables helps stabilize Blood sugar and reduce cholesterol. Pectins, found in apples, pears, prunes and plums, are a particularly useful form of water-soluble fiber.

    Insoluble fiber, in cereals, wheat bran and vegetables, reduces the risk of colon-related problems. In addition to adding fiber to the diet, dried beans and soybeans have been shown to lower cholesterol, improve vascular health and kidney functioning, preserve bone mineral density and reduce menopausal discomforts (AJCN 1999 Sept; 70(3 suppl):464S-74S). Fiber also promotes good bowel health and encourages the growth of beneficial intestinal flora.

    You need 25 to 40 grams of fiber daily. If you have cut back on your carbohydrates, be sure to take a reliable fiber supplement.

    Fantastic Fats

    Do you have problems focusing on mentally challenging tasks? If so, you should eat more fish and get more of the omega-3 fatty acids that fish and flax contain. Higher levels of this type of fat have been linked to better concentration while performing demanding intellectual work (Lipids 2004 Feb; 39(2):117-23).

    Fats add flavor to food, making meals taste better. Monounsaturated fats like plain olive oil and canola are liquid at room temperature and are suitable for use in cooking at high temperatures. Researchers have found that a diet high in monounsaturated fat has the ability to decrease LDL (bad) cholesterol (J Nutr 2001; 131:1758-63). Other fats, such as extra virgin olive oil and flaxseed oil, are best used in dishes that don't need cooking, such as salads.

    Although the RDI for fat is less than 30% of the total calorie intake, some researchers believe that if you eat healthy fat, eating too much is not a concern. Omega-3 fats are available in supplement form.

    Wonderful Water

    Do you suffer from dry skin? You may not be drinking enough water. This precious liquid is used by every cell of our bodies and makes up 60% to 75% of our body weight. Water is important for kidney function. Researchers in Italy found that drinking adequate amounts of water can help prevent the formation of kidney stones (Urol Int 2004; 72 Suppl 1:29-33).

    Your activity level, environment and diet influence how much water you need daily. Try to drink at least eight cups of fluid a day from noncaffeinated, nonalcoholic sources.

    Voluptuous Vitamins

    Do you exercise frequently? If you do, you need more antioxidant vitamins like natural vitamin E and vitamin C as well as a healthy supply of carotenoids. A study at the School of Applied Medical Sciences and Sports Studies, University of Ulster, found that exercisers need more antioxidants. Otherwise, their exertion may release an excess number of free radicals (caustic molecules) in their bodies and do damage to the heart arteries and other internal organs.

    Vitamins, in general, are defined as micronutrients that are necessary for life. They are necessary for the production of energy, a healthy immune system and hundreds of other functions in the body.

    Vitamins aren't the only substances that produce big benefits in small quantities. Phytonutrients are chemicals in plants that have health-promoting properties. These nutrients are getting more and more attention from researchers who are keeping score on our nutritional requirements.

    Mineral Crunch

    Do your meals contain plenty of calcium? If not, you may need supplements to keep your bones strong and help keep your weight down. One study, presented at the Experimental Biology 2003 meeting in San Diego, found that young women who consumed more calcium had better luck controlling their weight. In this research, it didn't take much calcium to make a difference in waistlines. Consuming just one more serving daily (a cup of milk or a thumb-sized piece of cheese, each of which contain about 300 mg of calcium) made, on average, about a two-pound difference.

    In addition, many experts recommend multimineral supplements (along with multivitamins) to promote better health. A recent study of people with immune problems, for instance, found that those kinds of supplements seem to help boost the immune system (AT News 2004 Feb 27; 398:4-5).



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    Hidden In Plain Sight - The spreading epidemic: Diabetes.
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    Date: June 12, 2005 06:02 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Hidden In Plain Sight - The spreading epidemic: Diabetes.

    Hidden In Plain Sight by Carl Lowe Energy Times, October 7, 2003

    Today, a devastating disease is striking millions of Americans. Sixteen million Americans already have this disease, and every day another 2,200 Americans learn they have it. The spreading epidemic: Diabetes.

    The potential ramifications: Millions of people more susceptible to heart disease, dementia, infections, amputations and blindness. Lowering your risk for diabetes is relatively simple and terribly important. Because dealing with some of its effects once you are its victim can be much more complicated.

    Signs of Trouble

    "Approximately one in four individuals over the age of 60 has type 2 diabetes, which is a remarkable statistic," says Gerald Shulman, MD, of the Howard Hughes Medical Institute at Yale University. "And, if you add impaired glucose tolerance [a condition that often leads to diabetes], you're talking about 40% of the population."

    The economic burden of this epidemic is staggering, estimated at about $100 billion a year and growing.

    If you never exercise, carry around a substantial amount of stomach fat and have seen your weight climb significantly over the years, you are among the people at higher risk for diabetes.

    These lifestyle habits eventually render your body unable to efficiently process Blood sugar. In technical terms, researchers investigating how the body uses and misuses Blood sugar have identified what they have called "syndrome X" or "metabolic syndrome," a condition that puts you at high risk for both diabetes and heart disease.

    If you have three or more of the following signs, you now have metabolic syndrome and, unless you change the way you live, may eventually suffer diabetes (Circulation 7/14/03):

    * Fat around your middle

    * High Blood pressure

    * High triglycerides (Blood fats)

    * Low level of HDL ("good" cholesterol)

    * High fasting Blood sugar

    In a study of more than 6,000 men in Scotland, having three of these metabolic problems almost doubled the risk of heart disease and more than tripled the risk of diabetes. If you have four of these risk factors, your risk of heart disease just about quadruples, and your diabetes risk skyrockets almost 25 times.

    Insulin Resistance

    The cells in your body get the energy they need to survive when they take sugar out of your Blood and oxidize it along with fatty acids. Normally, insulin, a hormone-like substance released by the pancreas, speeds the absorption of Blood sugar by the cells. When your pancreas cannot make insulin at all or makes too little, you suffer what is called type 1 or juvenile diabetes. This condition is usually treated by taking insulin.

    But if your pancreas secretes what should be enough insulin for glucose absorption, and your cells are still unable to take sufficient sugar from your Blood, you have what is called type 2 or adult-onset diabetes.

    Understanding exactly why cells develop difficulties in taking sugar out of the Blood and using it for energy has long troubled medical investigators. This condition, before it develops into full-blown diabetes, is called insulin resistance. Researchers have now linked it to malfunctioning mitochondria, the little structures in cells that make the energy that keeps cells functioning.

    Scientists have long known that, as you age, you become more susceptible to diabetes. And when researchers compare the mitochondria in young people with those found in the cells of the elderly, they find that older mitochondria are more sluggish.

    Making Energy

    The mitochondria within the cells oxidize glucose and fatty acids to make energy. (They accomplish this in a complicated metabolic action called the Krebs cycle.) Difficulty with this process, or insulin resistance, can occur when fat and fatty acid waste products accumulate in your liver and muscle tissue.

    "We hypothesized that there were two routes to this type of fat accumulation," says Dr. Shulman. "One is that the fat cells might release more fatty acids to be delivered to muscles and/or defects in mitochondrial oxidation might then lead to the accumulation of these fatty acids."

    Research confirms that fatty molecules probably collect in muscle cells because the mitochondria's ability to burn fat breaks down over the years. On average, mitochondrial activity dips about 40% in older people.

    Dr. Shulman thinks that the final coup de grace in the development of diabetes from insulin resistance takes place when the mitochondria malfunction in the insulin-producing cells of the pancreas.

    Although Dr. Shulman says that more research is needed to understand why mitochondrial function slips with age, he recommends keeping your mitochondria from slacking off by exercising. Studies now show that regular physical activity can probably increase the mitochondria in your muscles by activating release of an enzyme called AMP kinase. "...an encouraging note in this study is that-since we've shown that exercise leads to more mitochondria by activation of [the enzyme] AMP kinase-by staying active, the elderly might...maintain mitochondrial content and head off such health problems," says Dr. Shulman. "This is yet another reason for seniors to maintain an active lifestyle," he adds.

    Maitake for Metabolic Syndrome

    Another natural way to fight the metabolic syndrome is with an extract of the maitake mushroom (Grifola frondosa). The extract, called sx-fraction, is attracting research investigating its ability to help the body manage Blood sugar more efficiently. In one study, five people with diabetes improved their Blood sugar levels with sx-fraction (Diab Med 2001; 18).

    This research found that taking maitake sx-fraction is often accompanied by drops in Blood glucose levels ranging from 30% to 63%. According to Mark Kaylor, PhD and Ken Babal, CN, in Syndrome X and SX-Fraction (Woodland), "...Studies have demonstrated that whole maitake or its fractions are potent agents for improving 'diabetic conditions.'"

    Take the Whole Grains Home

    Eating a daily dish of whole grains, like whole wheat and brown rice, can also reduce your risk of diabetes (AJCN 8/22/03). In a twelve-year study of more than 40,000 men between the ages of 40 and 75, researchers found that those who ate three servings of whole grains a day cut their risk in half.

    The researchers found that even overweight people lowered their chances of diabetes by eating whole grains and exercising.

    Consuming more magnesium also helped; whole grains contain amounts of this mineral missing in refined-grain foodstuffs. Magnesium improves insulin response.

    In an age of junk food, our simple taste for sugar and refined grains may threaten our health. Yet, your defense against this scourge is no further away than simply eating more fibrous foods and going for a simple, everyday walk.



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    Energy Vitamins
    TopPreviousNext

    Date: June 11, 2005 05:50 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Energy Vitamins

    Energy Vitamins by Daniel Mowrey, PhD Energy Times, June 7, 1998

    Do you suffer groggy mornings clouded with tired and achy feelings? Do you have to struggle to muster sufficient energy to cope with the day? Then, throughout the morning and afternoon, does frequent fatigue, weakness or depression persist on your horizon like an ugly storm cloud? And your evening may bring little relief as you slump into bed for a restless night, only to begin the same routine the next morning. If lack of vim and vigor plagues your days and nights, your body may be suffering from an inability to synthesize sufficient energy.

    Our lives depend on processing the food we eat into substances our cells can take in and use. In a never-ending cycle, our body breaks food down and reconstructs the components to form body structures and burn as energy.

    How much you exercise, the food and supplements you eat and how much you sleep influence the efficiency of these processes.

    Vitamins and Energy

    Certain nutrients are called vitamins because they are crucial for vitality. These nutrients are essential to a productive life, the starting point for all life-giving and life-sustaining processes. Because of vitamins' crucial role in energy production, many people can perk up their stamina simply by consuming an adequate supply of vitamins in their daily diet. Since many vitamins - especially the ones concerned with energy - must be constantly replenished, a decent diet and the right supplements must be consumed every day.

    Be Energetic with B Vitamins

    Vitamins, especially the B vitamins, play extremely important roles in producing cellular energy. Their most important roles are shown in the illustration on page 48. The chart on page 46 lists the key vitamins and describes their effects as well as the consequences of not getting enough of them. Their effect is felt most profoundly in the energy producing process known as the Krebs cycle (which we'll explain in a moment).

    Vitamins B2 and B3, for example, supply the major building blocks for substances called flavin adenine dinucleotide (FAD and FADH) and nicotinamide adenine dinucleotide (NAD and NADH) which are critical elements of producing energy in the Krebs cycle as well as a process called oxidative phosphorylation.

    Even though you may never have heard of NAD and NADH, these molecules are found in many places in your body; they play a role in hundreds of biochemical reactions in all kinds of cells. B vitamins also combine with other materials to build coenzymes, chemicals which help form other chemicals necessary for cellular energy. B vitamins are crucial: miss out on one or more and you may break these metabolic chains necessary for peak energy.

    Energy to Spend

    The main energy currency of every cell is ATP: adenosine triphosphate. This material is used by cells for every imaginable task including reproduction, growth, movement and metabolism. Specialized metabolic cycles within the cell are designed to generate ATP.

    Consequently, the more ATP our cells create, the more energy can be generated. The raw materials used to make cellular energy are glucose (Blood sugar) and "free" fatty acids. The best way to supply your cells with the sugar they need is to consume complex carbohydrates which also supply fiber and other nutrients. When you eat carbohydrates, they are made into glucose which is stored as a starch called glycogen in muscles and the liver. Your body can rapidly turn glycogen into glucose for extra energy (The process of making energy from glycogen yields carbon dioxide and water as well as ATP.)

    Making Energy

    The first step in making glucose into energy is called glycolysis. This complicated process requires nine different steps. During these steps, glucose is made into a substance called pyruvate. The process of glycolysis requires ATP, but yields twice as much ATP as is present when it starts.

    From here, the process gets a little more complicated as pyruvate enters into a complex chain of events in tiny cellular structures called mitochondria. (Many metabolic events take place in the mitochondria.) The pyruvate molecules are converted to a molecule known as acetyl coenzyme A and eventually made into carbon dioxide, water and more ATP. This process is known as the Krebs cycle or citric acid cycle. It also involves a series of events known as oxidative phosphorylation in which NADH formed during the Krebs cycle is oxidized to form ATP.

    Why is fat such a concentrated source of energy? Free fatty acids enter the Krebs cycle to help generate ATP much more efficiently than glucose - producing roughly six times more energy per gram than glucose.

    Get Your Vitamins Every Day

    While we rely on our diet to supply many of our vitamins, a B complex supplement and multi-vitamins can ensure you consume sufficient amounts of these crucial nutrients.

    Many experts agree that a diet rich in raw fruits, nuts and vegetables that minimizes saturated fat can supply adequate a-mounts of these nutrients. Other supplements that may aid energy production:

    Alpha Lipoic Acid, an antioxidant that works in the fatty tissues of cell membranes and in cells' watery interiors. CoQ10, a nutrient that protects cell membranes, especially of the heart, against oxidation and toxins. Plus, herbs such as suma, ginseng and licorice root as well as creatine, carnitine and pyruvate.

    Of course if you suffer from any long term, intractable fatigue, consult your health practitioner. But for most cases of decreased vim and vigor, adequate vitamins should help your body recover your get up and go.



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    TopPreviousNext

    Date: June 09, 2005 05:36 PM
    Author: Darrell Miller (dm@vitanetonline.com)

    Energy Vitamins by Daniel Mowrey, PhD Energy Times, June 7, 1998

    Do you suffer groggy mornings clouded with tired and achy feelings? Do you have to struggle to muster sufficient energy to cope with the day? Then, throughout the morning and afternoon, does frequent fatigue, weakness or depression persist on your horizon like an ugly storm cloud? And your evening may bring little relief as you slump into bed for a restless night, only to begin the same routine the next morning. If lack of vim and vigor plagues your days and nights, your body may be suffering from an inability to synthesize sufficient energy.

    Our lives depend on processing the food we eat into substances our cells can take in and use. In a never-ending cycle, our body breaks food down and reconstructs the components to form body structures and burn as energy.

    How much you exercise, the food and supplements you eat and how much you sleep influence the efficiency of these processes.

    Vitamins and Energy
    Certain nutrients are called vitamins because they are crucial for vitality. These nutrients are essential to a productive life, the starting point for all life-giving and life-sustaining processes. Because of vitamins' crucial role in energy production, many people can perk up their stamina simply by consuming an adequate supply of vitamins in their daily diet. Since many vitamins - especially the ones concerned with energy - must be constantly replenished, a decent diet and the right supplements must be consumed every day.

    Be Energetic with B Vitamins
    Vitamins, especially the B vitamins, play extremely important roles in producing cellular energy. Their most important roles are shown in the illustration on page 48. The chart on page 46 lists the key vitamins and describes their effects as well as the consequences of not getting enough of them. Their effect is felt most profoundly in the energy producing process known as the Krebs cycle (which we'll explain in a moment).

    Vitamins B2 and B3, for example, supply the major building blocks for substances called flavin adenine dinucleotide (FAD and FADH) and nicotinamide adenine dinucleotide (NAD and NADH) which are critical elements of producing energy in the Krebs cycle as well as a process called oxidative phosphorylation.

    Even though you may never have heard of NAD and NADH, these molecules are found in many places in your body; they play a role in hundreds of biochemical reactions in all kinds of cells. B vitamins also combine with other materials to build coenzymes, chemicals which help form other chemicals necessary for cellular energy. B vitamins are crucial: miss out on one or more and you may break these metabolic chains necessary for peak energy.

    Energy to Spend
    The main energy currency of every cell is ATP: adenosine triphosphate. This material is used by cells for every imaginable task including reproduction, growth, movement and metabolism. Specialized metabolic cycles within the cell are designed to generate ATP.

    Consequently, the more ATP our cells create, the more energy can be generated. The raw materials used to make cellular energy are glucose (Blood sugar) and "free" fatty acids. The best way to supply your cells with the sugar they need is to consume complex carbohydrates which also supply fiber and other nutrients. When you eat carbohydrates, they are made into glucose which is stored as a starch called glycogen in muscles and the liver. Your body can rapidly turn glycogen into glucose for extra energy (The process of making energy from glycogen yields carbon dioxide and water as well as ATP.)

    Making Energy
    The first step in making glucose into energy is called glycolysis. This complicated process requires nine different steps. During these steps, glucose is made into a substance called pyruvate. The process of glycolysis requires ATP, but yields twice as much ATP as is present when it starts.

    From here, the process gets a little more complicated as pyruvate enters into a complex chain of events in tiny cellular structures called mitochondria. (Many metabolic events take place in the mitochondria.) The pyruvate molecules are converted to a molecule known as acetyl coenzyme A and eventually made into carbon dioxide, water and more ATP. This process is known as the Krebs cycle or citric acid cycle. It also involves a series of events known as oxidative phosphorylation in which NADH formed during the Krebs cycle is oxidized to form ATP.

    Why is fat such a concentrated source of energy? Free fatty acids enter the Krebs cycle to help generate ATP much more efficiently than glucose - producing roughly six times more energy per gram than glucose.

    Get Your Vitamins Every Day While we rely on our diet to supply many of our vitamins, a B complex supplement and multi-vitamins can ensure you consume sufficient amounts of these crucial nutrients.

    Many experts agree that a diet rich in raw fruits, nuts and vegetables that minimizes saturated fat can supply adequate a-mounts of these nutrients. Other supplements that may aid energy production:

    Alpha Lipoic Acid, an antioxidant that works in the fatty tissues of cell membranes and in cells' watery interiors. CoQ10, a nutrient that protects cell membranes, especially of the heart, against oxidation and toxins. Plus, herbs such as suma, ginseng and licorice root as well as creatine, carnitine and pyruvate.

    Of course if you suffer from any long term, intractable fatigue, consult your health practitioner. But for most cases of decreased vim and vigor, adequate vitamins should help your body recover your get up and go.



    --
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    Ellagic Active - Raspberry Extract - Promotes Healthy Cells ...
    TopPreviousNext

    Date: June 01, 2005 01:22 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Ellagic Active - Raspberry Extract - Promotes Healthy Cells ...

    Ellagic Active - Raspberry Extract

    You may think raspberries are strictly a summertime indulgence. Yet scientists know this simple fruit is far more valuable than a delicious snack or gourmet dessert. Raspberries have the highest content of ellagitannins— amazing health compounds— which are converted into ellagic acids in the body. These compounds are highly regarded for their positive effects on the growth and regulation of various cells and tissues, including those in the breast, pancreas, esophageal, skin, colon and prostate. Ellagic acid is also a powerful antioxidant (even stronger than vitamin C) that supports DNA integrity and promotes overall cell health, according to animal and in-vitro research. Source Naturals offers ELLAGIC ACID in response to a breakthrough in cell research. We strive to be ahead of mainstream nutritional science and are passionate about our commitment to informed health choices.

    Protective Benefits

    Dieticians have long stressed the importance of the consumption of fruits and vegetables for general health and well-being, but now these food items are being recognized as even greater contributors to human health. We know that ellagic acid binds to DNA, and acts as a shield, protecting DNA and increasing the expression of the enzyme p21, which arrests division of cells with DNA damage. Raspberries contain phytochemicals that provide protective action: One study showed that ellagic acid was able to induce the production of NAD(P)H:quinone reductase (QR), a major detoxification enzyme. Ellagic acid acts as a free radical scavenger to “bind” irritant-causing chemicals, making them inactive. Ellagic acid stimulates the activity of the enzyme glutathione-S-transferase that supports healthy cell growth.

    Extensive Research

    Raspberry is also a traditional remedy in support of the gastrointestinal and respiratory tract. It is used to promote healthy Blood vessels, as a mouth and throat remedy and is said to help maintain a “normal, balanced feeling” in the stomach. Research studies on the protective effects of ellagic acid have been extensive—there are approximately 126 published studies. Berries also contain a natural form of salicylates, which provide cardio support. British researchers analyzed the Blood of subjects and found salicylates were present from dietary sources, including raspberries and blackberries. Researchers at the National Center for Health Statistics (NCHS) in Hyattsville, Maryland established a connection between reduced health risks and increased intake of salicylates. Animal tests also suggest that red raspberry may reduce levels of glucose (Blood sugar) to support normal Blood sugar levels.

    Potent Defense

    Research in the past decade has determined that ellagic acid is one of the most exciting and promising compounds for its striking effect on cell division, regeneration and growth. While ellagic acid has been found to occur naturally in 46 different foods, red raspberry has been identified as having the highest natural content. Each tablet contains 300 mg of raspberry leaf extract (40% ellagitannins), which is ten times higher than other raspberry products. Source Naturals again joins forces with your natural foods retailer to bring you this unparalleled supplement.

    References:
    Daniel. 1991. Quantification and liberation of ellagic acid in dietary sources, Diss Abstr Int [B]; 51(10), 4787. Festa, Aglitti, Duranti, Ricord, Perticon, Cozzi. 2001. Strong Antioxidant Activity of Ellagic Acid in Mammalian Cells. Anticancer Research 21: 3903-08. Narayanan, Gian. 2001. Re: Down Regulation Associated Cell Cycle Arrest. Anticancer Research 21: 359-64. Singh, Khanna, Visen, Chander. 1999. Protective Effect of Ellagic Acid. Indian J Exp Biol 37 (9), 939-940. Xue, Aziz, Sun, Cassady. 2001. Inhibition of Cellular Transformation by Berry Extracts. Carcinogenesis 22(2) 351-356.



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    TopPreviousNext

    Date: May 09, 2005 06:10 PM
    Author: Darrell Miller (dm@vitanetonline.com)

    It's in the Blood

    Natural alternatives abound for managing cholesterol levels, backed by a growing body of research ©VR By Paul Bubny

    The National Cholesterol Education Program (NCEP) last July lowered the threshold for considering the use of statin drugs—a move which some say was motivated more by profits than scientific evidence. For example, the Center for Science in the Public Interest pointed out that eight of the nine authors behind the new recommendations had financial ties to statin manufacturers, which stand to reap billions of dollars more from a category that grossed $14 billion in the U.S. last year. And though the Food and Drug Administration (FDA) in January decided against authorizing over-the-counter (OTC) sales of statin drugs, drug companies would still like to see this happen.

    “The medical establishment’s pushing of these drugs to becoming the number one category of prescribed drugs in the world has led them to keep lowering the total cholesterol number that triggers the drug recommendation,” said Neil E. Levin, C.C.N., D.A.N.L.A., nutrition educator, product formulator, and “Truth Advocate” for NOW Foods (Bloomingdale, IL), which produces a number of supplements for addressing cholesterol. “This is despite the lack of evidence that total cholesterol means much as regards cardiovascular risks.

    “Other tests are much more important in terms of predicting risks, including CRP (C-reactive protein), the balance of different cholesterol fractions, and homocysteine,” he continued. “Add adult-onset diabetes to the risk factors for cardiovascular disease (CVD).”

    At the same time, the allegation that enormous sales potential lay behind the lower threshold for prescribing statin drugs illustrates how widespread the problem of hypercholesterolemia (elevated total cholesterol) is. More than 100 million Americans have elevated cholesterol (total cholesterol values of 200 mg/dl and higher), and of these, more than a third have high cholesterol (levels of 240 mg/dl and higher), according to the American Heart Association. Those numbers have unfavorable implications for the incidence of CVD, as high cholesterol is considered a risk factor for coronary heart disease and stroke.

    While statin drugs haven’t garnered the same degree of negative publicity that COX-2 inhibitors have suffered lately, safety concerns have arisen nonetheless. For one thing, these drugs lower the liver’s production of coenzyme Q10 (coQ10) along with its production of cholesterol. “CoQ10 is related to energy production and immune functions, is an antioxidant, and [is] an important cardiovascular nutrient,” Levin said. “It is not good to lower one’s coQ10 levels by half!”

    Moreover, said Levin, statins increase the tendency of muscle tissues to break down. “Combined with inactivity or certain drugs, this can stimulate muscle wasting,” he said. “Muscle is where a good deal of calories are burned, so a loss of muscle could affect mobility and energy production, potentially adding to obesity problems. These muscle changes occurred in patients and persisted for years after treatment was discontinued, as shown by muscle biopsies, even if no obvious muscle problems were observed by the patients.”

    And the last word on the subject may not have been spoken. Predicted Dr. Frank King, Jr. president of King Bio Natural Medicine (Asheville, NC), “Once the appropriate studies are finished, these drugs, along with hypertensives, will hit the fan bigger than the COX-2 inhibitors.”

    Also looking toward the future, Levin said that of the 20 million Americans who will be “targeted” for statin drug prescriptions under the new NCEP guidelines, “Some of these will want to try natural methods first. Others will rebel at the side effects of the drugs and experiment with alternative products.”

    King and Levin both saw opportunity for natural products in the fallout from drug safety concerns, with King projecting that sales of his company’s cholesterol-related homeopathic remedies will double in 2005. “The reports of deaths from drugs will always overshadow the trumped-up studies and news reports blasting dietary supplements,” said Levin. “Vioxx knocked vitamin E off the media’s radar screens pretty rapidly, though we still see ignorant reporters citing that [Johns Hopkins] vitamin E analysis as if it were true. But the comparable safety of supplements means that open-minded people will want to at least try natural therapies before signing in to a lifetime of drug therapies. Meanwhile, the studies on natural products will continue to build our credibility.”

    Those studies keep coming in, with at least four major findings published in the past few months, plus a heart-health claim on walnuts authorized by FDA. They join a raft of earlier findings that link natural products—branded and otherwise—to healthy cholesterol levels.

    "Blur of Products"

    With so many natural alternatives to cholesterol drugs available, it can be hard to keep track. “As with any other category, the blur of products as they cascade over several shelves means that the retailer needs to have a good sense of what works and what they want to recommend to their customers,” Levin said. “Really, each person needs a protocol that would include antioxidants, fiber, vitamins, herbs, and oils. The pre-mixed cholesterol support formulas are a good starting place.”

    To help retailers get a sense of “what works,” here is an alphabetical discussion of several nutrients that have demonstrated benefits in serum cholesterol levels. They include the following:

    Barley may help lower cholesterol, according to a report in the American Journal of Clinical Nutrition (2004, vol.80, no.5: 1185-1193). Twenty-five adults with mild hypercholesterolemia consumed a controlled diet low in total fat, saturated fat, and cholesterol for 19 weeks. They then added whole-grain products containing barley to their diets that contained low (0 g), medium (3 g), or high (6 g) amount of beta-glucan per day for five weeks. Total cholesterol was reduced by 4 percent 9 percent, and 10 percent, respectively. The diet with the highest amount of beta-glucan led to a decrease in LDL cholesterol of 17 percent.

    Chromium. There’s evidence, Levin said, that chromium in doses of 500 mg a day may decrease levels of low-density lipoprotein (LDL, the so-called “bad” cholesterol) and total cholesterol while raising levels of high-density lipoprotein (HDL, or “good” cholesterol). At the annual meeting of the American College of Nutrition last October, a poster presentation on the safety of Benicia, CA-based InterHealth Nutraceuticals’ ChromeMate niacin-bound chromium won first prize; among other things, the presentation cited chromium’s role in maintaining healthy Blood lipid levels.

    Fatty Acids. The latest in a long line of studies demonstrating the benefits of fatty acids in heart health is a study published in The International Journal of Clinical Pharmacology and Therapeutics in December 2004. It showed that docosahexaenoic acid (DHA), an omega-3 fatty acid, can restore normal Blood vessel function in children with inherited high cholesterol. The study, which used Martek DHA produced from microalgae, concluded that restoration of normal Blood vessel function has the “potential for preventing the progression of early coronary heart disease in high-risk children.”

    “The evidence continues to accumulate on the cardiovascular benefits of DHA for people of all ages,” said Henry “Pete” Linsert, Jr., chairman and CEO of Martek Biosciences, an ingredient supplier based in Columbia, MD. “This study clearly indicates that DHA played an important role in healthy Blood vessel function in the children in this study.”

    On the Omega-Research.com Website maintained by fish oil manufacturer Nordic Naturals (Watsonville, CA) can be found summaries of several earlier studies linking omega-3 fatty acids to maintaining healthy Blood lipid levels, as well as related benefits such as elasticity of the arteries. In a 2003 study published in the American Journal of Clinical Nutrition, it was found that women receiving a mixture of 4 g eicosapentaenoic acid (EPA) and DHA along with 2 g of gamma-linolenic acid (GLA) had lower levels of LDL cholesterol after 28 days compared to those who received either the EPA/DHA supplements without DHA, EPA/DHA with a smaller dose of GLA, or GLA alone.

    Flax is another source of omega-3s, and Arkopharma/Health From The Sun (Bedford, MA) offers FiProFLAX in a variety of forms. Marketing director Hugues P. Mas said the flax is “QAI [Quality Assurance International] certified organic and guaranteed GMO [genetically modified organism]-free.” On its Website, the company offers a cholesterol quiz geared to consumers, discussing the importance of omega-3s as well as other nutrients.

    Garlic. Adding to an already considerable body of research demonstrating that garlic can lower total cholesterol, LDL cholesterol, and triglycerides while increasing HDL cholesterol, researchers at UCLA in 2003 reported that Kyolic aged garlic extract reduced or inhibited plaque formation in the arteries of 19 cardiac patients taking statin drugs.

    Lead researcher Matthew Budoff, Ph.D. commented at the time that the study “suggests that aged garlic extract may be a useful and beneficial dietary addition for the people who have high cardiovascular risk or who have undergone heart surgery.” Budoff has since presented several trade show seminars sponsored by Los Angeles-based Wakunaga of America, the makers of Kyolic.

    Guggul. In use for centuries as a component of Ayurvedic medicine, guggul—a gummy resin tapped from the Commiphora mukul tree, which is native to India—has been studied since the early 1960s for its hypolidemic (Blood-lipid lowering) properties. Sabinsa Corp. (Piscataway, NJ), an ingredient supplier which produces a standardized extract under the brand name Gugulipid, says the studies on guggul indicate that its hypolipidemic activity can be attributed to more than one mechanism of action.

    Among the possible mechanisms are: inhibition of cholesterol biosynthesis, enhancing the rate of excretion of cholesterol, promoting rapid degradation of cholesterol, thyroid stimulation, alteration of biogenic amines, and “high affinity binding and anion exchange.”

    Homeopathy. “Homeopathy activates the body’s own control system to work properly,” said King. “This is the safest and most curative approach to take.

    “Forcing the body into biochemical change even naturally doesn’t actually have the curative action of homeopathy,” King continued. “Homeopathy can even correct the genetic predispositions to disease we may have inherited from as deep as a thousand years into our family chain.” King Bio makes Artery/Cholesterol/BP, a homeopathic formula intended to help tone heart muscles and Blood vessels.

    Low glycemic index foods. In a study published in the February issue of the American Journal of Clinical Nutrition, researchers found that high glycemic load is negatively correlated to serum levels of HDL cholesterol. Assessing the relationship between Blood levels of lipids and diet in a test population of 32 healthy males and females ages 11 to 25, the researchers found that glycemic load accounted for 21.1 percent of the variation in HDL cholesterol. They concluded that glycemic load appears to be an important independent predictor of HDL cholesterol in youth and noted that dietary restrictions without attention to glycemic load could unfavorably influence Blood lipids.

    Medicinal Mushrooms. Although its product SX-Fraction is intended primarily to address high Blood sugar, Maitake Products, Inc. (MPI, Ridgefield Park, NJ) found in a clinical study that LDL cholesterol in diabetic patients declined modestly (from 142 mg/dl to 133 mg/dl) over a two-month period. Those taking SX-Fraction also lost about 7 lbs. in the same time period.

    “The more impressive lowering of cholesterol, however, comes from the dietary fiber that is found in all medicinal mushrooms,” said Ellen Shnidman, manager of scientific affairs at MPI. She cited animal studies which documented the cholesterol-lowering properties of four different mushrooms: maitake, shiitake, agaricus, and enokitake.

    For example, a study reported in the September 1996 issue of Alternative Therapies showed “a 44 percent reduction in total cholesterol in rats consuming maitake mushroom in their diet,” said Shnidman. “This cholesterol reduction is accompanied by weight loss, relative to rats eating a similar high-choelsterol diet without mushrooms. Apparently, cholesterol is excreted by the rats in sufficient quantity to aid in weight loss.”

    Oat bran. A 2004 consumer study conducted by the Natural Marketing Institute (NMI, Harleysville, PA) for Nurture, Inc. (Devon, PA), which produces the ingredient OatVantage, found that 63 percent of consumers managing their cholesterol levels prefer oat-based ingredients.

    Oat bran is the subject of a health claim authorized by FDA in 1999, and NMI research found that 69 percent of respondents preferred the FDA-permitted health claim, “Helps Lower Cholesterol,” over the model structure-function claim, “Helps Maintain Healthy Cholesterol Levels.” “This is significant for food, beverage, and dietary supplement manufacturers who want to increase sales by using a more consumer-desired claim on the product label,” said Griff Parker, Nurture CEO.

    Plant sterols. Also the subject of an FDA-approved claim for heart health, plant sterols (structurally similar to cholesterol in humans) can block the absorption of cholesterol, according to a number of studies. In an “Ask the Doctor” publication (available online at www.atdonline.org), Decker Weiss, N.M.D. noted that sterols enter the same receptor sites that cholesterol enters on its way to the Bloodstream. “The cholesterol, being blocked from absorption, remains in our intestines where it is eventually excreted,” Weiss wrote. General Mills has just introduced Yoplait Healthy Heart, a yogurt high in plant sterols.

    Policosanol. A mixture of fatty alcohols derived from sugar cane or beeswax, policosanol has been favorably compared in clinical studies to several types of prescription drugs for managing cholesterol. On its own, policosanol was found in a 1999 study to reduce LDL cholesterol while raising levels of HDL cholesterol.

    Probiotics. “Several studies have indicated that consumption of certain cultured dairy products resulted in reduction of serum cholesterol, as well as triglycerides,” wrote Dr. S.K. Dash, president of probiotic manufacturer UAS Laboratories (Eden Prairie, MN), in his Consumer Guide to Probiotics. Among other studies, Dash cited two controlled clinical studies from the VA Medical Center at the University of Kentucky.

    “In the first study, fermented milk containing [Lactobacillus] acidophilus was accompanied by a 2.4 percent reduction of serum cholesterol concentration,” he wrote. “In the second study, a different L. acidophilus strain reduced serum cholesterol concentration by 3.2 percent. Since every 1 percent reduction in serum cholesterol concentration is associated with an estimated 2 to 3 percent reduction in risk for coronary heart disease [CHD], regular intake of fermented milk containing an appropriate strain of L. acidophilus has the potential of reducing risk for [CHD] by 6 to 10 percent.”

    Dash said his company’s DDS Probiotics contain DDS-1 L. acidophilus, “which has been researched and demonstrated to show cholesterol-lowering effect.”

    Psyllium. “Internal cleansing is very important” in maintaining healthy cholesterol levels, “especially if you do it with a lot of fiber,” said Sunil Kohli, vice president of Chino, CA-based Health Plus, Inc. The cholesterol-managing ability of fiber in general and psyllium in particular is “very well-established,” he said.

    However, Kohli said, “It will probably do you no good if it’s random. It should be done on a regular basis, and it should be supervised. Consulting the doctor or pharmacist is important.”

    Soy. The protein in soy “has evidence of lowering total cholesterol and LDL cholesterol, based on reviews of studies using over 20 g of soy protein per day,” said Levin. “Soy isoflavones are considered only partly responsible for this effect.”

    Sytrinol. A patented proprietary formula derived from natural citrus and palm fruit extracts and containing citrus polymethoxylated flavones and palm tocotrienols, Sytrinol has been shown in clinical trials to improve total cholesterol, LDL cholesterol, and triglycerides by up to 30 percent, 27 percent, and 33 percent, respectively. Having just wrapped up Phase III of a long-term trial of Sytrinol, Chicago-based SourceOne Global Partners, which owns the exclusive worldwide license for intellectual property associated with the ingredient, is commencing a study that combines Sytrinol with plant sterols.

    Tocotrienols. On its Website discussing the science and benefits of tocotrienols (www.tocotrienol.org), ingredient supplier Carotech Inc. (Edison, NJ) identifies several benefits for Blood lipid levels. Tocotrienols, according to the Website, have been shown to “inhibit cholesterol production in the liver, thereby lowering total Blood cholesterol;” “[suppress] hepatic HMG-CoA reductase activity [and result in] the lowering of LDL cholesterol levels;” and “inhibit cholesterogenesis by suppressing HMG-CoA reductase.”

    New Weapons

    There are also nutrients that are emerging as potential weapons in the fight against cholesterol. Levin cited rice bran oil, resveratrol, pantethine, l-carnitine, and niacin as showing promise.

    With all of this, Levin said, it’s important for retailers to remember that “they are not allowed to discuss diseases and remedies unless there is an approved FDA health claim allowed on the label, as with soy protein and plant sterols. What is allowed are structure-function claims such as ‘cholesterol support,’ ‘promoting normal, healthy circulation,’ ‘homocysteine regulators,’ etc.”

    Supplementation is only one tool for managing cholesterol levels, manufacturers pointed out. “Besides nutrition, lifestyle is a key to controlling cholesterol,” Levin said. “Eating a variety of antioxidant-rich foods will prevent the liver from churning out cholesterol as a ‘cheap’ antioxidant. The body uses oxidized cholesterol to patch leaky and damaged Blood vessels, so the ability to build healthy collagen is a must, using nutrients like vitamin C, Pycnogenol, rutin, hyaluronic acid, and MSM.

    “Don’t forget exercise and stress reduction,” he added. “Stress results in high cortisol levels—usually accompanied by poor Blood lipid levels—and a lack of good sleep to produce unhealthy people.” VR

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