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Vitanet ®

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Date: July 15, 2005 09:28 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: ST. JOHN’S WORT AND AIDS/HIV

ST. JOHN’S WORT AND AIDS/HIV

In 1991, some of the first work focusing on St. John’s wort’s effects on AIDS and the HIV virus began. Science magazine reported on the first study using the isolated hypericin, a key compound in Hypericum.16 Fred Valentine and Howard Hochster, researchers at New York University Medical Center, began one of the first studies looking at how hypericin can help uninfected T-cells from being infected with the AIDS virus in a cell culture. Their focus was on hypericin because it is a virucidal agent, meaning it can precisely target new virus particles and prevent them from infecting other cells.

The only two drugs at that time approved for treating HIV infection—AZT and ddI—work by interfering with the key viral enzyme, reverse transcriptase. Since hypericin works more effectively than many drugs in regards to the reverse transcriptase phase, and since many animal tests have shown that it has low toxicity at therapeutic doses, researchers (including Valentine and Hochster) began these studies largely hoping that not only would hypericin work on its own, but that it would have a sort of synergistic effect when used with either AZT or ddI. 17

Additional studies are pointing to St. John’s wort, and more so, hypericin, as having great potential in treating HIV. Acosta and Fletcher recently detailed the processes in which the human immunodeficiency virus works to infect human cells, and point out that hypericin is at least somewhat effective in inhibiting the four main phases of virus “growth”— binding and entry, reverse transcriptase, transcription and translation, and viral maturation and budding (the researchers note that hypericin is especially effective in binding and entry, the first phase.) This denotes that hypericin could eventually have special importance in completely stifling the development of the growth of any virus, and most importantly, that of the HIV virus.18

Another study assessing the use and ATTITUDEs of HIV sufferers concerning the use of more alternative treatments for the virus as opposed to clinical drug therapies showed both an extensive use of unconventional therapies and a very favorable response to using the alternative treatments, which, of course, St. John’s wort was among. “Participants at all sites expressed positive views upon increasing unconventional remedies.”19 The fact is that the world of synthetic medicines has been basically ineffective in not only treating and relieving the symptoms of AIDS, but also in finding a cure for the dreaded disease. Sufferers are giving alternative therapies a try, and the results are very promising.

A 1995 review appearing in Photochemisty-Photobiology treated the photodynamic properties of both hypericin and the structurally related hypocrellins for their anticancer and antiviral properties (especially the anti-human immunodeficiency virus). This article states that the promising anticancer and antiviral results obtained both in vitro and in vivo [in differing studies] have led to intensive investigation into their photo-physical and photochemical processes, especially kinetic studies of their intramolecular proton transfer . . . The biomedical advances of hypericins have been further promoted by significant progress in their chemical synthesis and the recent commercialization of . . . hypericin.20

Another study published in the September 1994 issue of Photochemistry-Photobiology gave hypericin the upper hand over the hypocrellins in treating HIV. Just one more vote in favor of promoting the use of St. John’s wort, and more specifically, hypericin, for use in treating HIV and in overall clinical medicine.

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Date: June 18, 2005 09:07 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Anti-Aging Nutrients

Anti-Aging Nutrients by Edward C. Wallace, DC, ND Energy Times, February 3, 2000

What's the big deal about trying to live longer? As you grow older (and the American population grows older alongside you) you may want to postpone the inevitable. Few wish to hasten "the journey from which no traveler returns." But as we approach that final bon voyage, chances are we desire clear sailing-aging without disability and with a peaceful, easy feeling.

How Do We Age?

Science has long puzzled about what causes the wrinkles, pains and deterioration of aging. In the search for causes, two basic theories have won over the most proponents: The first holds that cells are programmed with biological clocks that predetermine how many times they can reproduce before becoming non-functional. This theory has been largely formulated by the researcher Leonard Hayflick, MD.

The second basic theory, introduced by Denham Harman, MD, PhD, in the mid 1950s, holds that cells eventually break down due to attack by caustic molecules called free radicals that cause oxidative stress.

Programmed Cell Theory

In the early '60s, Dr. Hayflick observed that human fibroblasts (cells from connective tissue) in the laboratory refused to divide more than about 50 times. Dr. Hayflick also found that even if he froze the fibroblasts after 20 divisions, they would remember that they only had 30 divisions left after thawing.

Fifty cell divisions have been called the "Hayflick limit." Based on this research, scientists theorize that cells maintain a genetic clock that winds down as old age ensues. Many researchers believe the hypothalamus gland is the force behind our aging clocks, signaling the pituitary gland to release hormones that cause aging.

Free Radical/Oxidative Stress Theory

The other popular theory of aging pictures the human body as a cellular battlefield where attackers called free radicals damage our cells and tissues, making them age. In this scenario, a process called oxidation is the chief aging villain. On a microscopic level, oxidation generally entails molecules or atoms losing electrons. (Gaining electrons is called reduction.) The molecules or atoms that take these electrons are oxidizing agents.

Free radicals are substances that can exist with missing electrons, making them readily able to donate or accept electrons and damage structures in cells. As such, they are highly reactive, binding with and destroying important cellular compounds. Most of the free radicals in your body are made during metabolic processes. More are added from the food you eat and environmental pollution. Most of these free radicals contain oxygen molecules. As each cell makes energy in little structures called mitochondria, free radicals result. These oxidant by-products can damage DNA, proteins and lipids (fats). Consequently, toxic by-products of lipid peroxidation may cause cancer, inhibit enzyme activity and produce mutations in genetic material that make you age faster.

DNA Repair Theory

Free radical damage to DNA can cause cells to mutate or die. Your body makes enzymes that can repair this damage and slow aging. But, over time, the amount of damage overwhelms the body's ability to fix things. As cells grow older, their ability to patch up DNA diminishes and the rate of damage proceeds faster than repair. The result: We age and eventually die.

What Can We Do?

The free radical theory of aging suggests that taking antioxidants (compounds known to prevent free radical damage) in our food or as supplements may slow aging.

In the publication Age (18 [51] 1995: 62), it was reported that "aging appears to be caused by free radicals initiated by the mitochondria at an increasing rate with age. Superoxide and hydrogen peroxide radicals formed by the mitochondria during normal metabolism are major risk factors for disease and death after about the age of 28 in developed countries. Antioxidants from the diet lower the production of free radicals without impairing essential reactions to maintain body function."

Antioxidant Protection

Common dietary antioxidants include: vitamins E and C, carotenes, sulphur containing amino acids, co-enzyme Q10 and flavonoids (a group of plant compounds or pigments responsible for the color in fruits and flowers). In addition, melatonin, DHEA and the amino acid compound glutathione may also prove of benefit.

Glutathione along with the enzyme glutathione peroxidase are an essential part of free radical "quenching." (Quenching means changing free radicals into benign substances no longer capable of harm.) Deficiencies may suggest a decreased capacity to maintain detoxification and metabolic reactions in which glutathione plays a role, resulting in increased free radical stress and/or lipid peroxidation. Drinking too many alcoholic beverages can result in glutathione deficiency.

In a study in which 39 healthy men and 130 healthy women between the ages of 20 and 94 were evaluated for glutathione levels, the older subjects had significantly decreased levels (especially in the 60 to 79-year-old group). The authors felt that physical health and longevity were closely related to glutathione levels (Jrnl Lab & Clin Sci 120(5), Nov. 1992: 720-725). Poor nutrition and/or deficiencies in essential micronutrients and many prescription medications may contribute significantly to detoxification capacity in an aged individual. All of these circumstances are common in the elderly.

Eating a poor diet that contains too many processed foods without many fruits and vegetables can compromise your body's ability to detoxify pollutants, toxins and other harmful compounds. That can set off metabolic processes capable of fomenting large increases in free radical stress that can accelerate aging. Unfortunately, even in a country as prosperous as our own, nutrient deficiencies are frequent, especially in older citizens.

Nutrition Deficiencies

A study that looked at what elderly people consumed compared their reported intake with the 1989 Recommended Dietary Amount (RDA) and 1980 RDA: One of four people consumed only two-thirds of the RDA for calories and 60% consumed less than two-thirds of the RDA for vitamin D. As for other nutrients, 50% were found to have inadequate zinc levels (less than two-thirds of the RDA), 31% lacked calcium, 27% were short of vitamin B6, 25% didn't get enough magnesium, 7% missed out on folate and 6% ate less than two-thirds of the requirement for vitamin C (Nutrition Reviews (II), September 1995: S9-S15).

When researchers examine what everyone in the U.S. eats, they find that only 9% of Americans consume the recommended five servings of fruits and/or vegetables per day (Proceedings of the National Academy of Sciences, Sept 1993).

A diet high in fruits and vegetables is naturally high in antioxidant compounds and is believed to help you live longer. Unfortunately, if you buy your produce in the supermarket, those fruits and vegetables may also be rich in pesticide and herbicide residues (Consumer Reports, March 1999). Obviously, organic produce lacks these residues. But, in any case, research continues to indicate that a diet low in meats and animal fat and high in vegetables protects against antioxidant damage.

Longevity Diets

A six-year study of 182 people over age 70 in rural Greek villages found that those following their traditional diet of olive oil, whole grain breads, fresh fruits and vegetables and wine were less likely to die during the study than those who consumed more red meat and saturated fat. The most important foods in lowering the risk of early death included fruits, vegetables, legumes (peas and beans), nuts, dairy products and cereals (BMJ 311, 1995: 1457-1460).

Another article in Epidemiology highlights the evidence that eating a vegetarian diet increases your chances of living longer. Included in this survey is a recent country-wide study of diet and health in China, showing that the traditional near vegetarian diet of 10% to 15% of calories coming from dietary fat reduced the chances of heart disease, diabetes and many types of cancers (Epidemiology 3[5], 1992: 389-391).

Staying Alive

Staying skinny and limiting what you eat may also increase longevity. Scientific studies have previously shown that being overweight can theoretically curtail your life, increasing the risk of heart disease, diabetes and other life-shortening conditions. Animal studies have also shown that restricting food can slow diseases associated with aging. Researchers believe that cutting calories helps your immune system stay younger by reducing the formation of substances that are called proinflammatory cytokines.

Specifically reducing your intake of fatty foods may decrease your chance of coming down with autoimmune diseases. Researchers think omega-6 fatty acid vegetable oils (like corn oil) may increase free radical formation and decrease levels of antioxidant enzyme messenger RNA in addition to other effects (Nutrition Reviews 53[4], 1995: S72-S79). Another study found that cutting calories lowers the levels of oxidative stress and damage, retards age-associated changes and extends maximum life span in mammals (Science 273, July 5, 1996: 59-63).

In yet another study, it was shown that caloric restriction early in the life of lab animals increased their life span by a whopping 40% (Australian Family Physician 23[7], July 1994: 1297-1305). Today's modern higher-fat, low-fiber diet with substantial sugar consumption represents everything the longevity researchers say you shouldn't eat.

Longevity and Exercise

Exercise may slow aging. When researchers looked at the exercise habits of 17,000 men, average age of 46, they found that those who took part in vigorous activity lived longer.

Exercise can improve both cardiac and metabolic functions within the body, while also decreasing heart disease risk. Even modest exercise has been shown to improve cholesterol and blood sugar levels (JAMA 273[15], April 19, 1995: 1179-1184). In a study of how exercise affects your chances of living longer, 9,773 men underwent preventive medicine examinations on two different occasions. When the researchers looked at who lived longest, they found the highest death rate was in men who were unfit during both physical exams.

The Treadmill of Life

The lowest death rate was in the men who worked out and were in good shape. The researchers concluded that for each minute increase in how long a man could keep treading on a treadmill (between the first and second exam) there was a corresponding 7.9% decrease in the risk of dying (JAMA 273 [14], April 12, 1995: 1093-1098).

Since exercise can increase oxygen consumption up to 10 times, boosting the rate of production of free radicals, researchers believe that older individuals need more antioxidant nutrients to protect them. In a paper published in Aging Clinical and Experimental Research (1997), researchers stated that if you regularly exercise in your golden years, you should take more antioxidant vitamins to compensate for this risk.

Longevity Supplementation

Melatonin is not often thought of as an antioxidant, but, instead, as a sleep aid. Melatonin, however, is an effective and efficient free radical scavenger and may help stave off the effects of aging. Melatonin protects against what are called hydroxyl free radicals. Research shows that older people's lack of melatonin may make them more susceptible to oxidative stress. In one study, researchers felt that new therapies aimed at stimulating melatonin synthesis may eventually lead to therapies for the prevention of diseases related to premature aging (Aging and Clinical Experimental Research 7[5], 1995: 338-339). Melatonin was shown to provide antioxidant protection in several ways.

Toning Down Enzymes

Melatonin can ease the effects of enzymes that generate free radicals, enhance the production of glutathione peroxidase (an antioxidant) and defuse the caustic action of free radicals that contain hydroxyls. In several studies, DHEA supplementation has been shown to potentially revive immune function in older adults (Exp. Opin. Invest. Drugs 4[2], 1995: 147-154).

In a study of 138 persons older than 85 years compared to 64 persons 20 to 40 years of age, scientists found that the younger people had four times as much DHEA in their bodies.

The researchers believe that our bodies make less and less DHEA as we get older. The authors of this study raise the possibility that declining DHEA may be partly to blame for our biological clocks running down (New York Academy of Sciences 1994: 543-552).

Vitamins E & C

A growing body of research also supports the benefits of taking vitamins E and C to hold off the effects of getting old. Researchers writing in Free Radicals and Aging (1992: 411-418) point out that as you get older your body is home to more and more free radical reactions that may lead to degenerative diseases like heart disease and arthritis. Research has found that in older people with exercise-induced oxidative stress, taking vitamin E every day may significantly fight off free radicals. (To investigate this effect, scientists measured waste products in urine that result from free radical reactions.) Their conclusion: Dietary antioxidants such as vitamin E may be beneficial.

Chronological Age Vs.Biological Age

Vitamin C also looks to scientists like a good anti-aging bet. Research in the Journal of Advancement in Medicine, (7[1], Spring 1994: 31-41) showed that folks consuming larger amounts of vitamin C were less likely to experience clinical problems at all ages. Those taking in less than 100 mg of vitamin C per day also suffered the most problems.

In this research, individuals over 50 years of age who daily consumed the largest amount of vitamin C were as healthy or healthier than the 40 year olds who were taking the least amount of vitamin C.

Similar Relationship

A similar relationship appears to exist for vitamin E and serum cholesterol levels. In a study of 360 physicians and their spouses, researchers found that people in their 50s who consumed more vitamin E had lower cholesterol than those in their 30s who were taking less.

And the longevity beat goes on: In a study evaluating environmental tobacco smoke and oxidative stress, researchers divided 103 people into three groups. Researchers blew smoke at 37 of these folks without protection while 30 of them got to breathe tobacco smoke but took antioxidant supplementation. Another 36 of them merely had to read magazines from doctors' offices. The results: After 60 days of supplementation the antioxidant folks had a 62% reduction in evidence of oxidative damage to their DNA. Cholesterol levels dropped and so did antioxidant enzyme activities. The researchers concluded that taking antioxidants provided a modicum of protection against environmental poisons.

The range of antioxidant nutrients used in this study included: beta-carotene, vitamin C, vitamin E, zinc and selenium as well as copper (Cancer Epidemiol Biomarkers Prev 7, November 1998: 981-988).

Carotenoids

When you mention carotene or carotenoids, most people think of the beta carotene that makes carrots orange. But more than 600 carotenoids are present in colorful vegetables and many of these misunderstood substances are more potent antioxidants than beta-carotene.

Carotenoids have been shown to destroy oxygen free radicals in lipids (fats), help protect our cells from the sun's ultra violet radiation and enhance our natural immune response (J. Nutr 119[1], Jan. 1989: 112-115).

Some evidence seems to show that how much carotenoids you (and other mammals) have in your cells may be the predominant factor in determining life span (Proc Natl Acad Sci 82 [4], 1985: 798-802). Therefore, a diet rich in carotenoids (leafy green vegetables, carrots, yams, sweet potatoes, squash, citrus fruits and tomatoes) along with supplementation seems to be just what the fountain of youth ordered.

Flavonoids

Flavonoids, a group of antioxidant plant pigments, seem to be able to protect specific organs. For instance, the flavonoids in milk thistle (Silybum marianum) have been used for ages for liver problems. Bilberry has been found protective for the eye and hawthorn for the heart and circulatory system.

Numerous studies have shown the many beneficial effects of flavonoids with perhaps the best known being the ability of anthocyanidins in wine and grape seed extract to help protect your blood vessels and capillaries from oxidative damage (Phytotherapy 42, 1986: 11-14; Am J Clin Nutr 61, 1995: 549-54).

Flavonoids are found in vegetables and such fruits as blackberries, blueberries, cherries and grapes. A diet rich in these foods helps ensure an adequate intake of these important nutrient compounds.

Amino Acid Health

Methionine and cysteine are sulphur containing amino acids (protein building blocks), both of which are essential in maintaining levels of glutathione, a substance that plays a major role in quelling free radicals. Studies have found that as we age, the level of these important amino acids in our bodies decreases. (NEJM 312 [1], 1985: 159-68). As it has been shown that adding cysteine to the diet of test animals can increase their life expectancy considerably, researchers believe these amino acids can help us live longer too.

ATTITUDE & Behavior

Get more sleep! A recent study showed that men who habitually napped were less likely to have a heart attack. The men in this research who regularly napped for at least 30 minutes per day had about a 30% reduction in heart problems while those who napped for a full hour had a 50% reduction compared to non nappers. Naps of longer duration did not seem to increase the benefit. In the same research, investigators also found that spending time with a pet or merely contemplating nature could also improve cardiac health. Sensuality, optimism and altruism also appeared to have health benefits (Family Practice News, December 15, 1998: 14-15).

In another study, this one in American Psychologist, researchers from the University of California found that people who are self-indulgent, pampered and achieve by running roughshod over the competition are less likely to outlive their healthy peers. Being egocentric, impulsive, undependable and tough-minded were predictors of poor physical health and a shorter life. So loosen up and be nice to your fellow humans! (U.C. Davis Magazine, Fall 1995: 14).

Longevity at Last

While no one has suggested that taking supplements, eating vegetables or exercising can, as of yet, extend the human life span past the generally recognized limit of about 120 years, researchers believe they can improve your odds of longer life. And by staying healthier, your old age will be more enjoyable, too.

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Vitanet ®

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Date: June 11, 2005 05:18 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The Flex Factor

The Flex Factor by Thomas Dunville Energy Times, February 10, 2004

Arthritis, according to recent research, presents its sufferers with a Catch-22: The nagging pain of this condition can send your spirits plummeting. But, then, the depression spurred by the disconsolate persistence of arthritic pain can make the condition worse.

Part of the trick is not to give in. If you can keep a bright mood even as your joints start to ache, the pain may lessen.

While nobody can offer a guaranteed, 100% effective cure for arthritis, you don't have to be a passive victim. Exercise, the proper nutrients and a positive, can-do ATTITUDE can ease arthritis pain so effectively that scientists have been able to measure the difference. While medical researchers recognize the existence of over 100 types of arthritis, most people with achy joints suffer from osteoarthritis, which is caused by everyday wear and is found in just about everyone over age 60. When this condition occurs, the body's cushioning, its cartilage, thins and the inner surfaces of joints grind together painfully.

Although aging itself increases your chances of enduring achy joints, other factors can also put you in the way of osteoarthritis. If you carry too much weight, it can wear on your joints. In addition, suffering a joint injury when you're young can increase your risk of developing osteoarthritis as you age.

In another prevalent form of joint pain, rheumatoid arthritis (RA), the body's immune system mistakenly attacks the membranes lining the joints, causing swelling and pain. About 2 million Americans suffer from RA, which affects women about twice as often as men.

Exercise Away Arthritic Woes

Weekend warriors, don't despair! Arthritis doesn't have to mean the end of your weekend athletic wars. Matter of fact, in many cases, experts now recommend exercise to reduce the effects of arthritis.

While that might sound counterintuitive, a study out of the Netherlands shows that folks in the early stages of rheumatoid arthritis who work out twice a week for about an hour each session may enjoy better physical and mental health than couch potatoes who receive physical therapy.

The Dutch study took 150 people, many of whom had just started to suffer from rheumatism, and enrolled them in RAPIT, an acronym for Rheumatoid Arthritis Patients in Training. Rather than letting these folks rest their inflamed joints, twice a week the research team took them to the gym where they did:

When the researchers compared the physical changes in these arthritis sufferers with 150 others with similar arthritis complaints who underwent physical therapy without organized physical activity, they found that after two years the exercisers had benefited greatly. They were stronger and more aerobically fit, could perform everyday tasks more effectively and possessed a better, more optimistic mental ATTITUDE (Arthritis and Rheumatism 2003; 48(9):2415-24).

However, the exercisers who were already suffering severe rheumatoid arthritis did experience some extra joint damage, so the researchers believe this kind of program is better for those in the early stages of the disease. " This study demonstrates that participation in long-term high-intensity exercise classes decreases the level of psychological distress in RA patients," says researcher Zuzana de Jong, MD, a professor at the Leiden University Medical Center in the Netherlands.

Fish Oil Lowers Arthritis Risk

Fish oil-in particular, cod liver oil-may be able to help ease osteoarthritis.

In looking at the effects of fish oil, researchers at Cardiff, Wales, discovered indications that "...the omega-3 fatty acids in cod liver oil can reduce cartilage degradation and inflammation in arthritic disease," according to Bruce Caterson, PhD, one of the scientists involved.

Dr. Caterson adds, "Our most recent work shows that by exposing human osteoarthritic cartilage to cod liver oil in the laboratory for just 24 hours we can turn off, or reverse, the action of the degradative enzymes and inflammatory factors affecting the tissue." John Harwood, PhD, another member of the Cardiff research team, adds, "This is where science and old wives' tales coincide. Our findings are consistent with advice that taking cod liver oil in early adulthood could prevent the onset of osteoarthritis and would reduce the harmful symptoms associated with the disease."

Dr. Caterson further explains that the omega-3 fatty acids in cod liver oil inhibit enzymes that break down aggrecan and collagen, substances that cushion joints. Consequently, cartilage stays healthier, inflammation is lessened and arthritic pain decreases. The anti-inflammatory action of omega-3s in fighting rheumatoid arthritis is also supported by studies performed in the US (Am J Clin Nutr 2000; 71(1 Suppl):349S-51S).

Other research shows that if you take natural vitamin E along with fish oil, you may improve even further your odds of relieving arthritis or lessening its effects (JACN 10/30/00).

Glucosamine Repair

Glucosamine, the stuff that cartilage is made from, has been shown to lower the risk of arthritis and possibly relieve its pain. This natural substance, made from a sugar and a molecule called an amine, is a building block of joint tissue. As a result, experts believe, when you take it in supplemental form, the body may use it to repair joints that have been damaged by arthritis. For instance, an investigation of osteoarthritis of the knee performed at the University of Liege in Belgium showed that taking glucosamine could stop joints from deteriorating.

The study, which involved more than 200 people suffering from osteoarthritis, found that in three years of taking glucosamine supplements, many arthritis sufferers found that their condition actually improved (Lancet 2001 Jan 27; 357).

Other Arthritis Fighters

Chondroitin sulfate is another material that goes into the making of cartilage. Chondroitin helps cartilage stay hydrated and permits the flow of nutrients through the joint tissues. In addition, researchers believe that chondroitin helps fight inflammation, which can otherwise cause pain and stiffness as well as joint destruction.

Taken together with glucosamine, chondroitin is believed to hasten the healing of bone and cartilage. Another substance that may help ease the ache of arthritis is methylsulfonylmethane (MSM), a naturally occurring sulfur-bearing compound. "MSM appears to have anti-inflammatory effects when administered orally, intravenously or topically," says MSM researcher Stanley Jacob, MD, FACS, of the Oregon Health & Science University. That means it has shown an ability to reduce the heat, pain and swelling associated with arthritic conditions. MSM may also be able to reduce muscle spasms around joints and reduce the formation of scar tissue.

Herbal Aid

Herbal medicine has long been used by folks with achy joints. The yellow spice turmeric (Curcuma longa), a staple of Indian cooking, is a traditional Indian remedy for arthritis because of its painkilling properties. Ginger (Zingiber officinale), another culinary favorite, restrains the production of inflammatory chemicals called cytokines. And willow bark (Salix sp), the source of aspirin, is longer-acting and doesn't irritate the stomach lining.

Those who suffer arthritis know that its pain and discomfort are often no laughing matter. But if you don't take arthritis lying down and manage to keep a smile on your face-and avail yourself of nature's remedies-you can get the upper hand on this often debilitating condition.

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Vitanet ®

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Date: June 11, 2005 03:49 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Thanks for the Memory

Thanks for the Memory by Estelle Sobel , February 6, 2002

Thanks for the Memory By Estelle Sobel

"I feel like every day, I lose my memory more and more. It started when I couldn't find my car keys, sometimes I forget directions. My mother has Alzheimer's so I'm concerned," says Jerry Solowitz, a 63 year old man.

Ellen Lerner, 37, sometimes worries that she can't keep track of everything in her job as a public relations executive. "I feel like stress can get to me easily, and I worry because I forget simple things like where I put a file."

Should these people be concerned?

"Yes," says Lynda Toth, Ph.D., co-author with Pavel Yutsis, M.D., of Why Can't I Remember? Reversing Memory Loss (Avery, 1999).

Jerry should start a specific program with a health practitioner who specializes in memory loss, due to lots of unsuspected new causes for memory dysfunction. Ellen needs to make lifestyle changes, as stress can definitely lead to memory loss.

"Cortisol, which is one of the stress hormones, can be harmful because it keeps calcium in the memory pathway too long and destroys the neurons, which is very damaging to the brain," notes Toth.

Why Does Memory Fail?

Memory fails for several reasons, says Augustine DiGiovanna, M.D., author of Human Aging: Biological Perspectives, (McGraw-Hill 2000), and Professor of Biology at Salisbury State University in Salisbury, MD.

Normal Aging: Much of diminished memory as we age is due to reduced blood flow to the brain from atherosclerosis, which is hardening and narrowing of the arteries. Decreased blood flow causes neurons to shrink and function less effectively.

Also, as we age we lose neurons and neuron connections that can lead to memory loss. So the way people think, how much they remember, and the mental activities they do determine how many brain cells survive through the years.

Finally, as people live longer, the chance is greater that the body's immune system and other defense mechanisms won't be able to protect against certain diseases that affect the brain and memory (Parkinson's, strokes, Alzheimers, atherosclerosis).

A Starving Brain: The brain is not getting fed the nutrients it needs (vitamins, minerals, amino acids, glucose). Without the right "food" the brain's energy levels become lowered and stop powering the memory cells. Then, free radicals can do more dirty work and continue to rust memory cells.

Drink And Sink: Alcohol passes through the blood-brain barrier and slows down the processing of information between memory neurons. Memory loss increases over time, as memory tissues shrink.

Sad Stories: Depression can imbalance the neurotransmitters and electrical charges of neurons.

Tense and Tight: High blood pressure can constrict and narrow blood vessels, limiting blood and oxygen flow to the brain.

Memory-Sustaining Supplements

One way to boost brain power is to take the right supplements.

Ginkgo biloba: The powerful medicinal herb ginkgo biloba increases blood flow and circulation to the head by dilating blood vessels in the brain, allowing more oxygenated blood to get to the neurons. It also protects against free radical damage.

Research: Ginkgo biloba extract displayed a significant effect on helping the mental abilities of people 50-59 years old (Phytotherapy Research 13, 1999: 408-415).

Pregnenolone: This powerful hormone regulates the balance between excitation and inhibition in the nervous system and helps enhance memory and brain function, possibly by repairing a fatty substance that is part of the myelin sheath that surrounds nerve cells. Research: A St. Louis University School of Medicine study on mice showed that pregnenolone enhanced memory and helped mice to navigate mazes better.

Huperzine A: This herbal supplement is derived from club moss found in China; in purified form it inhibits the enzyme that breaks down acetylcholine, a neurotransmitter produced in the brain that you need for memory.

Research: Studies conducted by Alan Mazurek, M.D., found that huperzine A in purified form improves memory, enhances focus and concentration and has been used to improve memory loss in Alzheimer's patients (Alt. Ther. in Health Med. 5 [2], March 1999: 97-98).

Another study in The Journal of Neuroscience Research showed that huperzine A is a potent inhibitor of cholinesterase, which penetrates the brain and produces a dose-dependent increase of the neurotransmitters acetylcholine, norepinephrine and dopamine in rat cortex (41, 1995: 828-835).

Phosphatidylserine (PS): This substance, which occurs naturally in nerve cell membranes, helps keep fatty substances soluble and cell membranes fluid and helps reduce levels of cortisone which are damaging to tissues.

Research: Phosphatidylserine encourages a sense of calm by raising the levels of alpha brain waves and increasing the production of acetylcholine (Neuropsychobiology 24, 1990-1991: 42-48).

Vitamin E: This potent antioxidant attaches to bad cholesterol and helps prevent free radical damage to cells.

Research: Age-related processes like memory function and problem solving can be affected by free radical damage. Several studies show that vitamin E might slow the effects of Parkinson's disease and Alzheimer's disease (JAMA 282, August 18, 1999: 621). Acetyl-l-carnitine: Increases cognitive performance because it rejuvenates cellular membranes of mitochondria, the storehouses of energy contained in every living cell.

Alpha-Lipoic Acid: Preserves memory tissue by increasing glutathione levels, which protect fat stores in neurons from being damaged.

Nine Ways to Remember

Dr. Lynda Toth suggests the following ways to make the most of what you've now got.

1) Power Up Your Smile. Remove dental fillings and replace them with porcelain or ceramic ones. The mercury in metal fillings may be harmful (some believe) and can affect the brain and nervous system, inflaming memory tissue and preventing the entry of nutrients into the cells.

2) Don't Be a Tin Man/Woman Avoid exposure to aluminum. Don't use aluminum pots to cook in. Aluminum accumulates in memory tissue, damaging cells. In fact, autopsies of Alzheimers patients show they have unusually huge amounts of aluminum in the brain. But no one knows where this aluminum comes from.

3) Eat Right. Eat organic and pesticide-free foods. Pesticides get into the cells and can damage DNA.

4) A Matter of Taste. Avoid foods with artificial coloring, monosodium glutamate (MSG, often called "natural flavors" or "natural seasoning"). Also avoid processed foods with taste enhancers called exito toxins such as l-cysteine and aspartic acid.

5) In the Raw. Make sure that your diet consists of enzyme-rich 50% raw foods (fruits and vegetables) to feed the brain. Eat less animal fats.

* Drink green juices to support levels of the brain's clean-up enzymes.

*Eat lots of fiber, which helps remove toxins from the body. Pick up psyllium fiber.

*Limit intake of processed sugar, caffeine and alcohol to lessen the load on the liver and pancreas.

6) Cut Bait. Watch the fish that you eat. Lots of ocean and inland-caught fish are contaminated with mercury. Go for deep, cold water fish such as cod. Avoid shark and swordfish.

7). Oil Up. Supplement your diet with omega-3 fatty acids, such as cod liver oil or flaxseed oil. These fats lubricate memory cells.

8) Work That Body. Stay fit and exercise. Exercise helps oxygenate the body, reduces cholesterol, and builds and energizes new memory cells which reduces wear and tear on the brain function.

9) Do Mind Games. Read, listen to music. Tune into different radio stations than the ones you normally listen to. Do crossword puzzles and a wide selection of word games which can stretch your brain and give it a tough workout.

Student of Life

You need to keep learning your whole life to keep your brain and memory in tip top shape. The brain is adaptable, and you are always building new neurons, says Dr. Toth, which means that there is no limit to how long it can develop. Anything that stimulates the brain will help it to grow. That's why as you get older it's even more important to take classes, start a new hobby, travel. In fact, the challenge of learning and doing new things (without stopping in a fit of frustration) causes your brain to grow, says Dr. Mazurek.

The Good News

As people get older, their brains may actually improve and repair themselves through a complicated process that is designed to eliminate faulty neurons that are prone to making mistakes. At the same time, brain activity goes on that results in the development of new and improved connections with neighboring neurons.

Research also shows that memory improves if you train people to have faith in themselves. (The brain helps those who help themselves.) Apparently, a confident perspective can encourage the brain to actually improve to the point where its new-found abilities may increase to the point where it fulfills expectations.

So keep your chin up and stay away from the artery-clogging saturated fat that can cut off the brain's blood supply. It's all in the ATTITUDE, says Dr. DiGiovanna. And, of course, the key to a long and happy life with your brain is also on the end of your fork and in that bottle of supplements.

Estelle Sobel, is the co-author of Beautiful Skin: Every Woman's Guide to Looking Her Best at Any Age (Adams Media, May 2000).

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Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=289)

Date: June 10, 2005 09:59 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Nutrients for Longevity

Nutrients for Longevity by Edward C. Wallace, ND, DC Energy Times, September 1, 1999

What's the big deal about trying to live longer? As you grow older (and the American population grows older alongside you) you may want to postpone the inevitable. Few wish to hasten "the journey from which no traveler returns." But as we approach that final bon voyage, chances are we desire clear sailing-aging without disability and with a peaceful easy feeling.

How Do We Age

Science has long puzzled about what causes the wrinkles, pains and deterioration of aging. In the search for causes, two basic theories have won over the most proponents: The first holds that cells are programmed with biological clocks that predetermine how many times they can reproduce before becoming non-functional. This theory has been largely formulated by the researcher Leonard Hayflick, MD.

The second basic theory, introduced by Denham Harman, MD, PhD, in the mid 1950s, holds that cells eventually break down due to attack by caustic molecules called free radicals that cause oxidative stress.

Programmed Cell Theory

In the early '60s, Dr. Hayflick observed that human fibroblasts (cells from connective tissue) in the laboratory refused to divide more than about 50 times. Dr. Hayflick also found that even if he froze the fibroblasts after 20 divisions, they would remember that they only had 30 divisions left after thawing.

Fifty cell divisions have been called the "Hayflick limit." Based on this research, scientists theorize that cells maintain a genetic clock that winds down as old age ensues. Many researchers believe the hypothalamus gland is the force behind our aging clocks, signaling the pituitary gland to release hormones that cause aging.

Free Radical/Oxidative Stress Theory

The other popular theory of aging pictures the human body as a cellular battlefield where attackers called free radicals damage our cells and tissues, making them age. In this scenario, a process called oxidation is the chief aging villain.

On a microscopic level, oxidation generally entails molecules or atoms losing electrons. (Gaining electrons is called reduction.) The molecules or atoms that take these electrons are oxidizing agents. Free radicals are substances that can exist with missing electrons, making them readily able to donate or accept electrons and damage structures in cells. As such, they are highly reactive, binding with and destroying important cellular compounds. Most of the free radicals in your body are made during metabolic processes. More are added from the food you eat and environmental pollution.

Most of these free radicals contain oxygen molecules. As each cell makes energy in little structures called mitochondria, free radicals result. These oxidant by-products can damage DNA, proteins and lipids (fats). Consequently, toxic by-products of lipid peroxidation may cause cancer, inhibit enzyme activity and produce mutations in genetic material that make you age faster.

DNA Repair Theory

Free radical damage to DNA can cause cells to mutate or die. Your body makes enzymes that can repair this damage and slow aging. But, over time, the amount of damage overwhelms the body's ability to fix things. As cells grow older, their ability to patch up DNA diminishes and the rate of damage proceeds faster than repair. The result: We age and eventually die.

What Can We Do

The free radical theory of aging suggests that taking antioxidants (compounds known to prevent free radical damage) in our food or as supplements may slow aging.

In the publication Age (18 [51] 1995: 62), it was reported that "aging appears to be caused by free radicals initiated by the mitochondria at an increasing rate with age. Superoxide and hydrogen peroxide radicals formed by the mitochondria during normal metabolism are major risk factors for disease and death after about the age of 28 in developed countries. Antioxidants from the diet lower the production of free radicals without impairing essential reactions to maintain body function."

Antioxidant Protection

Common dietary antioxidants include: vitamins E and C, carotenes, sulphur containing amino acids, co-enzyme Q10 and flavonoids (a group of plant compounds or pigments responsible for the color in fruits and flowers). In addition, melatonin, DHEA and the amino acid compound glutathione may also prove of benefit.

Glutathione along with the enzyme glutathione peroxidase are an essential part of free radical "quenching." (Quenching means changing free radicals into benign substances no longer capable of harm.)

Deficiencies may suggest a decreased capacity to maintain detoxification and metabolic reactions in which glutathione plays a role, resulting in increased free radical stress and/or lipid peroxidation. Drinking too many alcoholic beverages can result in glutathione deficiency.

In a study in which 39 healthy men and 130 healthy women between the ages of 20 and 94 were evaluated for glutathione levels, the older subjects had significantly decreased levels (especially in the 60 to 79-year-old group). The authors felt that physical health and longevity were closely related to glutathione levels (Jrnl Lab & Clin Sci 120(5), Nov. 1992: 720-725).

Poor nutrition and/or deficiencies in essential micronutrients and many prescription medications may contribute significantly to detoxification capacity in an aged individual. All of these circumstances are common in the elderly.

Eating a poor diet that contains too many processed foods without many fruits and vegetables can compromise your body's ability to detoxify pollutants, toxins and other harmful compounds. That can set off metabolic processes capable of fomenting large increases in free radical stress that can accelerate aging. Unfortunately, even in a country as prosperous as our own, nutrient deficiencies are frequent, especially in older citizens.

Nutrition Deficiencies

A study that looked at what elderly people consumed compared their reported intake with the 1989 Recommended Dietary Amount (RDA) and 1980 RDA: One of four people consumed only two-thirds of the RDA for calories and 60% consumed less than two-thirds of the RDA for vitamin D. As for other nutrients, 50% were found to have inadequate zinc levels (less than two-thirds of the RDA), 31% lacked calcium, 27% were short of vitamin B6, 25% didn't get enough magnesium, 7% missed out on folate and 6% ate less than two-thirds of the requirement for vitamin C (Nutrition Reviews (II), September 1995: S9-S15).

When researchers examine what everyone in the U.S. eats, they find that only 9% of Americans consume the recommended five servings of fruits and/or vegetables per day (Proceedings of the National Academy of Sciences, Sept 1993).

A diet high in fruits and vegetables is naturally high in antioxidant compounds and is believed to help you live longer. Unfortunately, if you buy your produce in the supermarket, those fruits and vegetables may also be rich in pesticide and herbicide residues (Consumer Reports, March 1999). Obviously, organic produce lacks these residues. But, in any case, research continues to indicate that a diet low in meats and animal fat and high in vegetables protects against antioxidant damage.

Longevity Diets

A six-year study of 182 people over age 70 in rural Greek villages found that those following their traditional diet of olive oil, whole grain breads, fresh fruits and vegetables and wine were less likely to die during the study than those who consumed more red meat and saturated fat. The most important foods in lowering the risk of early death included fruits, vegetables, legumes (peas and beans), nuts, dairy products and cereals (BMJ 311, 1995: 1457-1460)

Another article in Epidemiology highlights the evidence that eating a vegetarian diet increases your chances of living longer. Included in this survey is a recent country-wide study of diet and health in China, showing that the traditional near vegetarian diet of 10% to 15% of calories coming from dietary fat reduced the chances of heart disease, diabetes and many types of cancers. (Epidemiology 3[5], 1992: 389-391).

Staying Alive

Staying skinny and limiting what you eat may also increase longevity. Scientific studies have previously shown that being overweight can theoretically curtail your life, increasing the risk of heart disease, diabetes and other life-shortening conditions. Animal studies have also shown that restricting food can slow diseases associated with aging. Researchers believe that cutting calories helps your immune system stay younger by reducing the formation of substances that are called proinflammatory cytokines.

Specifically reducing your intake of fatty foods may decrease your chance of coming down with autoimmune diseases. Researchers think omega-6 fatty acid vegetable oils (like corn oil) may increase free radical formation and decrease levels of antioxidant enzyme messenger RNA in addition to other effects. (Nutrition Reviews 53[4], 1995: S72-S79). Another study found that cutting calories lowers the levels of oxidative stress and damage, retards age-associated changes and extends maximum life span in mammals (Science 273, July 5, 1996: 59-63).

In yet another study, it was shown that caloric restriction early in the life of lab animals increased their life span by a whopping 40% (Australian Family Physician 23[7], July 1994: 1297-1305). Today's modern higher-fat, low-fiber diet with substantial sugar consumption represents everything the longevity researchers say you shouldn't eat.

Longevity and Exercise:

Exercise may slow aging. When researchers looked at the exercise habits of 17,000 men, average age of 46, they found that those who took part in vigorous activity lived longer.

Exercise can improve both cardiac and metabolic functions within the body, while also decreasing heart disease risk. Even modest exercise has been shown to improve cholesterol and blood sugar levels (JAMA 273[15], April 19, 1995: 1179-1184).

In a study of how exercise affects your chances of living longer, 9,773 men underwent preventive medicine examinations on two different occasions. When the researchers looked at who lived longest, they found the highest death rate was in men who were unfit during both physical exams.

The Treadmill of Life

The lowest death rate was in the men who worked out and were in good shape. The researchers concluded that for each minute increase in how long a man could keep treading on a treadmill (between the first and second exam) there was a corresponding 7.9% decrease in the risk of dying. (JAMA 273 [14], April 12, 1995: 1093-1098).

Since exercise can increase oxygen consumption up to 10 times, boosting the rate of production of free radicals, researchers believe that older individuals need more antioxidant nutrients to protect them. In a paper published in Aging Clinical and Experimental Research (1997), researchers stated that if you regularly exercise in your golden years, you should take more antioxidant vitamins to compensate for this risk.

Longevity Supplementation

Melatonin is not often thought of as an antioxidant, but, instead, as a sleep aid. Melatonin, however, is an effective and efficient free radical scavenger and may help stave off the effects of aging.

Melatonin protects against what are called hydroxyl free radicals. Research shows that older people's lack of melatonin may make them more susceptible to oxidative stress. In one study, researchers felt that new therapies aimed at stimulating melatonin synthesis may eventually lead to therapies for the prevention of diseases related to premature aging (Aging and Clinical Experimental Research 7[5], 1995: 338-339). Melatonin was shown to provide antioxidant protection in several ways.

Toning Down Enzymes

Melatonin can ease the effects of enzymes that generate free radicals, enhance the production of glutathione peroxidase (an antioxidant) and defuse the caustic action of free radicals that contain hydroxyls.

In several studies, DHEA supplementation has been shown to potentially revive immune function in older adults (Exp. Opin. Invest. Drugs 4[2], 1995: 147-154).

In a study of 138 persons older than 85 years compared to 64 persons 20 to 40 years of age, scientists found that the younger people had four times as much DHEA in their bodies.

The researchers believe that our bodies make less and less DHEA as we get older. The authors of this study raise the possibility that declining DHEA may be partly to blame for our biological clocks running down (New York Academy of Sciences 1994: 543-552).

Vitamins E & C

A growing body of research also supports the benefits of taking vitamins E and C to hold off the effects of getting old. Researchers writing in Free Radicals and Aging (1992: 411-418) point out that as you get older your body is home to more and more free radical reactions that may lead to degenerative diseases like heart disease and arthritis. Research has found that in older people with exercise-induced oxidative stress, taking vitamin E every day may significantly fight off free radicals. (To investigate this effect, scientists measured waste products in urine that result from free radical reactions.) Their conclusion: Dietary antioxidants such as vitamin E may be beneficial.

Chronological Age Vs. Biological Age

Vitamin C also looks to scientists like a good anti-aging bet. Research in the Journal of Advancement in Medicine, (7[1], Spring 1994: 31-41) showed that folks consuming larger amounts of vitamin C were less likely to experience clinical problems at all ages. Those taking in less than 100 mg of vitamin C per day also suffered the most problems. In this research, individuals over 50 years of age who daily consumed the largest amount of vitamin C were as healthy or healthier than the 40 year olds who were taking the least amount of vitamin C.

Similar Relationship

A similar relationship appears to exist for vitamin E and serum cholesterol levels. In a study of 360 physicians and their spouses, researchers found that people in their 50s who consumed more vitamin E had lower cholesterol than those in their 30s who were taking less. And the longevity beat goes on: In a study evaluating environmental tobacco smoke and oxidative stress, researchers divided 103 people into three groups. Researchers blew smoke at 37 of these folks without protection while 30 of them got to breathe tobacco smoke but took antioxidant supplementation. Another 36 of them merely had to read magazines from doctors' offices. The results: After 60 days of supplementation the antioxidant folks had a 62% reduction in evidence of oxidative damage to their DNA. Cholesterol levels dropped and so did antioxidant enzyme activities. The researchers concluded that taking antioxidants provided a modicum of protection against environmental poisons.

The range of antioxidant nutrients used in this study included: beta-carotene, vitamin C, vitamin E, zinc and selenium as well as copper (Cancer Epidemiol Biomarkers Prev 7, November 1998: 981-988).

Carotenoids

When you mention carotene or carotenoids, most people think of the beta carotene that makes carrots orange. But more than 600 carotenoids are present in colorful vegetables and many of these misunderstood substances are more potent antioxidants than beta-carotene.

Carotenoids have been shown to destroy oxygen free radicals in lipids (fats), help protect our cells from the sun's ultra violet radiation and enhance our natural immune response (J. Nutr 119(1), Jan. 1989: 112-115).

Some evidence seems to show that how much carotenoids you (and other mammals) have in your cells may be the predominant factor in determining life span (Proc Natl Acad Sci 82 [4], 1985: 798-802). Therefore, a diet rich in carotenoids (leafy green vegetables, carrots, yams, sweet potatoes, squash, citrus fruits and tomatoes) along with supplementation seems to be just what the fountain of youth ordered.

Flavonoids

Flavonoids, a group of antioxidant plant pigments, seem to be able to protect specific organs.

For instance, the flavonoids in milk thistle (Silybum marianum) have been used for ages for liver problems. Bilberry has been found protective for the eye and hawthorn for the heart and circulatory system.

Numerous studies have shown the many beneficial effects of flavonoids with perhaps the best known being the ability of anthocyanidins in wine and grape seed extract to help protect your blood vessels and capillaries from oxidative damage (Phytotherapy 42, 1986: 11-14; Am J Clin Nutr 61, 1995: 549-54).

Flavonoids are found in vegetables and such fruits as blackberries, blueberries, cherries and grapes. A diet rich in these foods helps ensure an adequate intake of these important nutrient compounds.

Amino Acid Health

Methionine and cysteine are sulphur containing amino acids (protein building blocks), both of which are essential in maintaining levels of glutathione, a substance that plays a major role in quelling free radicals. Studies have found that as we age, the level of these important amino acids in our bodies decreases. (NEJM 312 [1], 1985: 159-68).

As it has been shown that adding cysteine to the diet of test animals can increase their life expectancy considerably, researchers believe these amino acids can help us live longer too.

ATTITUDE & Behavior

Get more sleep! A recent study showed that men who habitually napped were less likely to have a heart attack. The men in this research who regularly napped for at least 30 minutes per day had about a 30% reduction in heart problems while those who napped for a full hour had a 50% reduction compared to non nappers. Naps of longer duration did not seem to increase the benefit.

In the same research, investigators also found that spending time with a pet or merely contemplating nature could also improve cardiac health. Sensuality, optimism and altruism also appeared to have health benefits (Family Practice News, December 15, 1998: 14-15).

In another study, this one in American Psychologist, researchers from the University of California found that people who are self-indulgent, pampered and achieve by running roughshod over the competition are less likely to outlive their healthy peers. Being egocentric, impulsive, undependable and tough-minded were predictors of poor physical health and a shorter life. So loosen up and be nice to your fellow humans! (U.C. Davis Magazine, Fall 1995: 14).

Longevity at Last

While no one has suggested that taking supplements, eating vegetables or exercising can, as of yet, extend the human life span past the generally recognized limit of about 120 years, researchers believe they can improve your odds of living longer. An added benefit: By staying healthier, your old age won't only be longer, it will be more enjoyable, too.

And, who knows, if you hang around long enough, taking your nutrients and getting a comfortable amount of consistent exercise, while meditating and refusing to succumb to stress, that magic bullet that will keep you alive for centuries may be discovered. Some day a new antioxidant or other substance may finally prove to provide the elusive fountain of youth. Stay tuned.

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Vitanet ®

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Date: June 10, 2005 09:51 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Immunity - The Big Picture

Immunity: The Big Picture by Brian Amherst Energy Times, August 3, 1999

Your body wants to be well. Outfitted with a battalion of defenses for strategic deployment, your immune system explodes with resistant force at the first sign of infective invasion.

Think of the time a tiny splinter embedded itself in your thumb. By bedtime, the spot rose and reddened; by morning, white blood cells had launched their campaign, building a hot, throbbing fortification. By day's end, the bit of wood was propelled to the surface and ejected by the immune system warriors. Once again, a foreign assailant was summarily ousted.

The Protective Force
The immune system is a dazzlingly complex mechanism charged with guarding against infection, colds, flu and cancer. Laced with networks of couriers and transmitters, backed up by intricate fail safe devices and reinforced by memory units, immunity constantly adapts to highly specific and evolving needs.

"Supporting the immune system is critical to good health. Conversely, good health is critical to supporting the immune system." So write naturopathic doctors Michael T. Murray and Joseph E. Pizzorno in their Encyclopedia of Natural Medicine (Prima).

Maintaining the immune system requires a comprehensive program of wholesome diet, resilient ATTITUDE, fitness enhancing activity and nutrients keyed to the clear and specific needs of this energetic machine.

The all-star lineup for immune sustenance: a high-potency multiple vitamin/mineral formula, vitamins C and A, bioflavonoids, isoflavones, zinc and selenium, antioxidants like ActiVin (grape seed extract) and pycnogenol (French maritime pine bark), as well as the botanicals echinacea and astragalus.

But optimal partnering with your immune system also benefits from understanding its workings.

The Battlefronts
The immune system wages war on the organ, tissue and cellular fronts. It encompasses the lymphatic vessels and organs (lymph nodes, thymus, spleen and tonsils), white blood cells, specialized cells in particular tissues and customized chemicals.

Lymph, a milky fluid consisting of water protein and immune cells, is the essence of the immune system. Powered by muscle movement (an important reason why exercise boosts immunity), the lymphatic system collects and transports lymph to the lymph nodes. These nodes contain certain immune cells and filter out invading antigens, as well as produce antibodies, before siphoning the lymph out into the bloodstream.

If you've ever had "swollen glands," that means your lymph nodes have been in overdrive.

Macrophages are the immune cells that filter lymph, consuming bacteria and cellular debris while protecting the lymph system from invasion and damage.

Gland Tidings
Two organs dominate immune function: n The thymus. The most influential, critical gland of the immune system, located just below the thyroid gland and above the heart; produces T lymphocytes, white blood cells responsible for cell-mediated immunity not controlled by antibodies. This immune response is tailored to specific antigens and is vital to resisting infection from mold-like bacteria including yeast, fungi, parasites and such viruses as Epstein-Barr, herpes simplex and hepatitis. It also protects against cancer, allergies and autoimmune disorders like rheumatoid arthritis. n The spleen. The largest mass (about seven ounces) of lymphatic tissue in the body, located in the upper left abdomen behind the lower ribs; it produces white blood cells, which engulf and destroy bacteria and cellular debris; recycles material from worn out red blood cells and platelets; produces immune system enhancing compounds, including the proteins tufsin and splenopentin, and spleen extracts.

The White Blood Cell Album
Although white blood cells (WBCs) are uniformly accountable for protecting the body against bacteria, viruses, fungi and parasites, the different types of WBCs vary considerably in form and function. n Neutrophils phagocytize, that is, eat, viruses, bacteria and old or dead cells. They don't need any biochemical messengers for activation and their effectiveness is wide-ranging.

In Monocytes collect cellular trash after infections and can trigger immune responses; eosinophils can eliminate foreign particles and, with basophils, are involved in immune response.

In Lymphocytes include varieties of T cells, which work with other white blood cells or attack and destroy foreign tissue, cancer cells or virus-infected cells; B cells that produce antibodies that bind to bacteria, viruses or tumors; and natural killer cells (NKCs) that destroy cancerous or virally-infected cells.

(Based on information in the Encyclopedia of Natural Medicine; The Road to Immunity: How to Survive and Thrive in a Toxic World (Pocket Books) by Kenneth Bock, MD, and Nellie Sabin; and the Johns Hopkins Family Health Book (Harper Resource).

Keep the System Sound
Your immunity mechanism calls for special care and support. The dilemma: How to develop a balanced system of complementary and alternative therapies to build and sustain powerhouse immunity? "There is no question that, in terms of immune system response, certain supplements can reduce infections, asthma, autoimmune disease and risk factors for cancer," says Samuel D. Benjamin, MD, former project director of the Arizona Center for Health and Medicine and an ardent advocate for complementary medicine.

"But you must always be sure to maintain the mind-body-spirit link," he told Energy Times. "For the mind, it could be exercise, yoga or meditation. Evidence shows improved immune system responses from these therapies. And in any case, you never read in the headlines that somebody has been admitted to the emergency room overdosing on meditation.

"Intentionality also is an important part of the mind link: believing you are going to fare well. For your spirit, you must ask yourself such questions as, Do I feel connected to others?

"For the body, a daily multivitamin and mineral supplement. Much depends on your community: I live on Long Island, where there is a high incidence of breast cancer, so I would recommend green tea and isoflavones from soy products for women."

Dr. Benjamin stresses moderation in the use of immune-intensifying supplements, among which he cites mixed carotenoids, zinc and vitamin E.

The Soy Solution
Scientists who took the cue from the apparent link between high-soy Asian diets and low cancer incidence have developed a compelling case for soy as an immune-supportive anticancer agent.

In a study conducted by the University of Southern California at Norris and published in the March 4, 1998 Journal of the National Cancer Institute, researchers reported that genistein, an active component of soy products, short-circuits the ability of tumor cells to elude destruction by the immune system due to an excess of defensive stress proteins.

Genistein seems to make cancer cells vulnerable to the immune response. Researchers at Wake Forest University told participants at the January 1999 meeting of the American Association for the Advancement of Science that dietary or supplemental soy fed to monkeys counteracted cell proliferation that is a cancer precursor.

That Championship C
Probably the most widely recognized immune accelerator is vitamin C, an honored warrior against scurvy and, in 1970, again celebrated by Linus Pauling for its preventive powers over the common cold.

Immune cells are known to accumulate and retain high levels of vitamin C. Researchers at Memorial Sloan-Kettering Cancer Center in New York now understand how that happens: Proteins called growth factors (which control growth and production of immune cells) also increase those cells' ability to take up vitamin C.

These researchers, reporting in the April 1998 issue of the journal Blood, explain that the additional glucose that the growth factors pump into immune cells (for enhanced energy), plus extra vitamin C, intensify immune response.

And folks with higher levels of vitamin C in their blood serum experience less cell damage from free radicals that leads to cancer, heart and pulmonary disease and other chronic conditions.

Scientists at the University of Buffalo (addressing the June 13, 1997 meeting of the Society for Epidemiologic Research) deduced from studying population groups that high levels of vitamin C are associated with low oxidative stress and lower risk of cell damage.

From A to Zinc
In Kids with neuroblastoma, a malignant tumor of embryonic nerve cells and the third most common form of childhood cancer, experienced significantly improved survival rates when their therapy included high doses of retinoic acid, a derivative of vitamin A, according to researchers at the University of California, San Francisco, and Childrens Hospital Los Angeles, who reported to the American Society for Clinical Oncology on May 18, 1998.

In Colostrum, the pre-milk liquid produced by mammals during the first 24 to 48 hours after birth, took the spotlight recently as a supplement imbued with multiple immune factors and natural antibiotics that augment body's immune response. A 1992 study showed that bovine colostrum might be able to reduce and prevente infections in immune deficient folks, especially those with AIDS.

In University of Pittsburgh Cancer Institute researchers found for the first time (on laboratory animals) that vitamin D appreciably inhibits widespread prostate cancer by binding to cancer cells and triggering cell death or their transformation to benign cells.

In Vitamin E exerts formidable immune-enhancing influence on both antibody and cell-mediated immunity. One fundamental study in the Journal of the American Medical Association (245, 1981: 53-58) established conclusively that vitamin E deficiency results in significant impairment of immune function. Later studies demonstrated that it reduces prostate cancer by up to one-third.

In Coenzyme A, described as a metabolic enzyme, takes part in starting numerous body processes that provide energy for the immune system. If you ever run short of this enzyme, fat processing within your body would grind to a halt.

in Researchers looking at a substance with the tongue twisting name 3-acetyl-7-oxo-Dehydroepiandro-sterone, believe it aids immunity by quelling stress hormones.

in Mushrooms contain natural substances called polysaccharides, believed to enhance immunity. In particular, maitake mushroom, which conveys the immune booster beta-D-glucans, is reputed to help fight infections and drop blood pressure.

in Men and women taking selenium supplements for 10 years had 41% less total cancer than those taking a dummy, according to a January 1997 study by Cornell University and the University of Arizona. Other studies have shown it to reduce the risk for colon cancer by about 60%. n Zinc may provide immediate protection against the all too common cold. Scientists at the University of Florida were the first to apply genetic fingerprinting methods like those used in criminal and paternity investigations to understand how nutrients directly affect human immune cells.

The study, in the April 1998 Journal of Nutrition, demonstrates that zinc signals cells to make the protein metallothionein, which protects against infections, toxins and other stressors.

Phytochemicals a la Carte
Researchers extol the powers of phytochemicals in fruits and vegetables available in dietary or supplement form as immune-igniting antioxidants. These compounds neutralize free radicals that oxidize cellular membranes, rendering them vulnerable to cancer.The Strang Cancer Prevention Center, an affiliate of New York Presbyterian Hospital, offers a menu of the top antioxidant phytochemicals. The center's director, Mitchell L. Gaynor, MD, is coauthor (with Jerry Hickey, RPh) of Dr. Gaynor's Cancer Prevention Program (Kensington): n Carotenoids, including beta-carotene from veggies and lycopene (the substance that lends the tomato is ruddy complexion), fight free radicals.

n Isoflavones from soy, fight angiogenesis, the process by which new blood vessels form to supply nutrients to cancerous growths. n Sulforaphane in broccoli, kale and cabbage activates anticancer enzymes.

n Omega-3 fatty acids in cold water fish block the synthesis of prostaglandins, natural compounds in the body that promote tumor growth.

n Ginger contains antioxidant compounds, each more potent than vitamin E. Recent studies on mice show ginger can prevent skin tumors. n Rosemary contains carnosol which deactivates carcinogens and helps limit the effects of prostaglandins.

Sometimes the world can look like a dangerous place, especially when you're sick and tired much of the time. But in the search for immunity, menus of health help like this ensure that no matter what your immunity needs, a boost can be yours with the proper nutrient selection.

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Vitanet ®

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Date: June 10, 2005 03:44 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The Science of Healthy Hair

The Science of Healthy Hair

by Susan Weiner Energy Times, January 5, 2002

From the strength-giving mane of Sampson to the magically long locks of Rapunzel, hair has had the power to captivate since biblical times. Today, its lure is just as compelling and hair remains an important form of self-expression and self-image. A healthy head of hair is more than an asset to your appearance. A hairstyle can reflect a mood, an ATTITUDE or a personal style, while unkempt hair may reveal the status of one's emotional or physical health. Even a "good" hair day vs. a "bad" hair day can significantly determine how your frame of mind takes shape. We can't always control the frizz factor or the humid weather that makes our curls fall flat, but many natural approaches are available to allow us to put our best looking follicle forward. Whether your hair is sleek and stylish, long and slinky, spiky punk rock-hip or wash-and-wear, botanical-based products and proper nutrition can bring out the very best in your locks.

Don't Fool Mother Nature

No matter how often you cut, dye, perm or blow-dry your hair, Mother Nature, with the help of your DNA, has blessed you with a quite specific quality and quantity of hair. Styling may work to change the appearance of your hair, but nothing can change your genetics. Every hair on your body, from the soft down on your arms to the coarser, longer hairs on your head, grows from a cell-lined indentation called a follicle. The hair follicle consists of three cylinders; the central cylinder determines whether your hair is straight, wavy or curly. Each hair shaft alternately grows or goes into a dormant phase. "At any one time, approximately fifteen percent of the one hundred thousand or so hairs on the head are resting, while the rest are growing or lengthening," say Arthur Balin, MD, PhD, and Loretta Pratt Balin, MD (The Life of the Skin: What It Hides, What It Reveals, and How It Communicates, Bantam). Hair constantly comes and goes, falling out consistently even when it is healthy. Consequently, a normal head can shed up to one hundred resting-phase hairs a day. When hair is subjected to harsh chemicals and treatment, even more may fall out. If you're concerned with hair loss, gently pull on a small section of hair; if fewer than five hairs come out, hair loss is within normal range.

What's Your Type?

Normal hair is an elusive commodity in these stressed-out days of over-washed, over-dried and chemically treated hair. If your tresses look frizzy, tangle easily or generally lack moisture, they're probably dry. Dry hair lacks the proper oil content to maintain an ample sheen and is usually dull-looking. To gain back a natural shine, cut back on shampooing and use a natural conditioner formulated for dry hair. Look for essential oils such as jojoba, evening primrose, blue chamomile, and white camellia, and B vitamins (such as panthenol) and aloe vera, suggests Aubrey Hampton, founder of Aubrey Organics. Drinking plenty of water, eating a diet that's not ultra-low in fats and using a humidifier may also help improve dull-looking dry hair, points out David E. Bank, MD (Beautiful Skin: Every Woman's Guide to Looking Her Best at Any Age, Adams Media). (Excessively dry hair may be a significant sign of metabolic disease. If you don't notice a marked improvement in your scalp after taking measures to improve dry hair, or your hair is abnormally dry, consult your health practitioner to see if stronger cures should be implemented.)

Too Much Oil

Hair that appears greasy within 24 hours after shampooing is oily. In that case, try gentle shampoos and herbal rinses with essential oils including quillaya bark, amino acids mixed with saponins, non-coloring henna and peppermint. For an oily scalp and dry ends, condition only the ends. Styling products should be oil-free. For thin or flyaway hair, products with natural thickening agents such as panthenol can help pump up the volume. Color treated and damaged hair can benefit from sulfur-containing amino acids; check your natural foods store for hair care products that contain horsetail, coltsfoot and cysteine. Tea tree oil products are effective when you are trying to control dandruff and a problem scalp.

The Must-To-Avoids

If the label lists sodium lauryl sulfate, steer clear, warns Hampton. And, says Dr. Bank, sodium C-14-16 olefin sulfonate, a harsh chemical found in cheap shampoos, is the worst of the worst when it comes to offensive hair care ingredients. "You also need to watch out for sodium chloride-table salt-in the ingredient list. It's a cheap ingredient to thicken shampoo and strips the hair of oils."

Feed Your Head

To optimize shine and fullness, improve your nutrition, says Bruce Miller, MD, author of The Nutrition Guarantee (Summit Publishing Group). "Good nutrition is as essential to healthy, attractive hair as it is to clear, glowing skin," notes Dr. Miller. "Your hair directly reflects your care and feeding of it." Your hair consists of about 97% protein, containing nineteen of the twenty-two amino acids that form protein, explains Dr. Miller. If you skimp on quality protein, your hair may reflect this amino acid imbalance by breaking, cracking and splitting. Hair follicles pass on the nutrients you consume, nourishing the new cells that form the growing hair shaft. As the hair gradually pushes upward, the shaft is continually lubricated by the busy sebaceous glands. For a smoother transition through the shaft and undamaged hair, lecithin provides a welcome dose of lubrication, as well as the important B vitamins choline and inositol, vital to healthy hair. In fact, the B vitamins are crucial to the growth of full bodied, healthy hair. The B complex strengthens, forms and smoothes the hair shafts, and helps maintain an even hair color, even warding off the beginning of gray hair. For thick and shiny hair, vitamin A works in conjunction with the B vitamins. Zinc can strengthen the hair shafts by thickening them. Thicker and stronger hair shafts increase your chances of holding on to your hair and suffering fewer lost hairs. When it comes to hair retention, genetics count. The more hair your parents retained, the greater your chance of keeping yours.

Think Diet

If you're interested in optimal hair health, think nutrition. Eating for the sake of your curls is a lot like eating for overall health: plenty of fresh fruits and vegetables, healthy grains and lean sources of protein, including tofu and other soy-based foodstuffs. To support healthy hair, some experts advocate foods high in biotin, including brown rice, brewer's yeast, bulgur, green peas, lentils, oats, soybeans, sunflower seeds and walnuts. The natural phytochemicals in green tea may aid hair, while ginkgo biloba improves circulation to the scalp. Don't forget your daily vitamins and be sure to take an iron and B12 supplement.

Chinese Treatment

Herbs from China show great promise for helping hair. He Shou Wu, made from Polygoni multiflori (the eastern wild rose), is reputed by devotees to restore color, slow hair loss, and help hair grow back. In Chinese medicine, this botanical has been used as an adaptogen to boost overall health and longevity. Within the context of Traditional Chinese Medicine (TCM), He Shou Wu is supposed to strengthen the liver and kidney meridians and support healthy blood. Many Asians use the herb to promote higher levels of qi, the TCM concept that encompasses your life's overall energy.

Show a Little Tenderness

Long-term exposure to sunlight and seawater can damage hair, as can combing or brushing wet hair. Treat your hair with kid gloves, use natural products that are gentle on hair, and avoid chemical treatments. If you're looking to lose weight, avoid crash diets; a sudden drop in nutrition can cause deficiencies and lead to hair damage and loss. Keeping a wonderful head of hair means staying ahead of the curve with proper nutrition, the right supplements and a continuous program of TLC. In that way, you can maintain the crowning head of hair you've always coveted.

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Date: June 10, 2005 03:31 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The Natural Man

The Natural Man

by Chrystle Fiedler Energy Times, July 14, 2003

Men face significant health challenges as they age. "When men go through andropause in their late 40s (like women go through menopause) and testosterone drops, these hormonal changes are associated with heart attacks, high cholesterol and diabetes," says Jacob E. Teitelbaum, MD, Director of the Annapolis Research Center for Effective Chronic Fatigue and Fibromyalgia Therapy in Maryland.

And although cardiovascular disease and cancer account for about two-thirds of men's deaths, says Michael Castleman, author of Blended Medicine (Rodale), men are also plagued by chronic pain (arthritis, especially from old athletic injuries), sexual problems and mental decline.

But men, and the women who love them, need not accept decline as an inevitable sign of aging. A natural man lifestyle makeover can make a difference. "Prostate problems can be significant [for men as they age]," says Jamey Wallace, ND, clinic medical director at the Bastyr Center for Natural Health in Seattle. "As men get older there can be an enlargement of the prostate that can cause urinary problems, with increased frequency and discomfort. There's a correlation between inactivity and weight gain and perhaps prostate problems as well." Besides lack of exercise, other contributing factors to health problems include a diet loaded with pesticide residues and chemicals, a lack of fiber and an excessive amount of unhealthy fats.

The Stronger Sex?

Women, on average, live five years longer than men. "At every age, American males have poorer health and a higher risk of mortality than females," says David Williams of the University of Michigan's Institute for Social Research. The gap in life expectancy between men and women may have both genetic and lifestyle origins. More men smoke than women, and men are twice as likely to be heavy drinkers. A recent study Williams led, published in the American Journal of Public Health, confirms that men's behavior is indeed a contributing factor to longevity or lack thereof. "Men take more risks than women," says Castleman. "Men ride motorcycles, go skydiving and do 'death-defying' things. Sometimes, death wins." A macho ATTITUDE can prompt men to practice risky behavior by, say, driving without a seat belt. Men also typically engage in more dangerous occupations like construction or fire fighting.

Get Him to the Health Practitioner

Being macho may also mean men postpone visits to their health practitioners. Women are twice as likely to schedule an annual checkup.

"Men postpone admitting and getting help for problems," says Shoshana Zimmerman, ND, author of My Doctor Says I'm Fine...So Why Do I Feel So Bad? (Blue Dolphin). "They may want to prove they are tough or are preoccupied with their jobs and responsibilities." "Starting in adolescence men feel they can take care of themselves," says Dr. Wallace. Unfortunately, this means that it may take a health crisis like severe pain to prompt a man's visit to a health practitioner. "Men care less about their health, so they don't take care of themselves as well as women do," says Castleman.

Get Him to Take the Long View

"Health problems are a result of decades of poor diet and not enough exercise," says Dr. Wallace.

Dr. Teitelbaum, author of From Fatigued to Fantastic (Avery/Penguin) says, as a rule of thumb, "Things that make you feel good are generally good for you." But there is a difference between a craving, say for sugar, and what makes you feel good. The difference is how you feel an hour after you've eaten something. Sugar may make you feel fatigued; a high-protein diet may make you feel energized. "If you have low energy, that's the time to add eggs and meat. Others need to be vegans. It's really individualized. Listen to your body."

Zinc is an important nutrient for men's health, particularly for the prostate, and can be found in pumpkin seeds. "Sprinkling a small handful on salads on a daily basis or bringing a small bag to the office and nibbling on those can be a helpful adjunct," says Dr. Wallace. Don't overdo zinc supplementation because high levels can lowers HDL-the good cholesterol-levels. If you do use supplements, follow package directions.

By eating different whole foods, you get optimal daily doses of vitamin A (in the form of mixed carotenoids); flavonoids; B vitamins; vitamins C, D, E and K; and important minerals like calcium, boron, manganese and magnesium, the single most critical nutrient. "It's also the one most Americans are deficient in," says Dr. Teitelbaum. "It promotes heart health, improves mental function and mood, helps you relax and sleep better." When sleep is elusive, herbs that can help include wild lettuce, Jamaican dogwood, hops, passionflower and valerian.

For many men, an enlarged prostate is part of aging. Saw palmetto (Serenoa repens) may reduce the frequent urge to urinate that can result.

"After age 40, men's levels of testosterone decline, while levels of other hormones, notably prolactin, increase," says Castleman. "This results in an elevation of the male sex hormone dihydrotestosterone, which is responsible for the overgrowth of prostate tissue that is characteristic of benign prostate enlargement. Many studies have shown that saw palmetto shrinks enlarged prostates and relieves symptoms." It takes about six weeks to work. (Since urinary difficulties can signal several health problems, it's important to consult a trained practitioner first.)

Give Him a Multivitamin

Add a good multivitamin with essential nutrients from a natural food store, says Dr. Wallace. "You'll find vitamins there with bioavailability. You can take something but it may be in a form that you can't assimilate. You need a multivitamin that your body can actually use."

Powdered vitamin formulas can be a good choice, says Dr. Teitelbaum, since they don't have binders or fillers. "You can just put it into a glass of say orange juice or mix it into a smoothie."

In addition, omega-3 oil offers antioxidant protection and anti-inflammatory action, says Dr. Zimmerman: "Especially on the arteries, which protects against plaque buildup."

Get Him Eating Better and Exercising

To help your spouse or significant other improve his health and vitality, start by setting a good example both in nutrition and activity.

"Eat a whole-food diet yourself, include foods like vegetables, fruits and whole grains like quinoa, teff and kamut (find them at your local natural food store) full of fiber and B vitamins, instead of refined bread and pasta," says Dr. Wallace. "Choose foods you both like. Go to a natural food store and look through whole food cookbooks, find recipes that use ingredients that you know your spouse likes and try those."

"Spend your time in the produce section, have salads and fruit salads in the fridge at all times, and serve them at all meals," says Castleman.

Make gradual, healthy substitutions, steps you both can live with. For example, replace one meat lunch and dinner a week with a vegetarian alternative, says Castleman. "Make a big pot of hearty bean and vegetable soup a week, and just keep it in the fridge for an easy heat-and-eat meal." You can also broil fish instead of frying it. Use olive or canola oil when cooking.

To get your four to five servings of vegetables each day, eat a five-color salad. "You'll get a variety of nutrients so the body can select what it needs from the different vegetables," says Dr. Wallace.

"Serve more vegetables, at least two with dinner and add fruit into your man's (and your own) diet," says Dr. Zimmerman. "Eating three each of protein, vegetables and fruits per day goes a very long way to improving health." So does drinking plenty of water, eight to ten glasses a day.

Besides providing a good example by eating healthy foods, a woman can do the same thing with exercise. "If a woman wants to start walking she can invite her husband to go along. Thirty minutes of walking every day can be very helpful," says Dr. Wallace. Walking, like sex, keeps the pelvic area active and improves prostate health by stimulating blood flow. Remember, in both diet and exercise, nagging doesn't work-while setting an example and trying to be inclusive, and not demanding, often makes a big difference for better health.

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Date: June 04, 2005 01:34 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Positive Thought - Balance Emotions and Mood...

As modern life becomes increasingly stressful, people are seeking out natural products that promote calmness and relaxation. But unless your supplement addresses multiple body systems, a healthy positive outlook may be out of reach. POSITIVE THOUGHTS Bio-Aligned Formula supports the interrelated systems and functions involved with emotional balance: inhibitory, stimulating and balancing neurotransmitters, and energy metabolism. This comprehensive herbal-nutrient blend features St. John’s wort, which has been clinically shown to support a good mood.

A Bio-Aligned Formula™

POSITIVE THOUGHTS is designed to bring alignment to the multiple, interconnected systems that influence a positive mood. Here’s how:

Neuro-Modulation—Inhibitory

Neurotransmitters are brain chemicals that aid in the process of nerve cell communication. Inhibitory neurotransmitters, such as GABA, reduce brain stimulation, helping to support a sense of relaxation and calm. The nerve cell membrane- stabilizing properties of taurine also support relaxation, as do the included herbs. In addition to supplying GABA and taurine, POSITIVE THOUGHTS supports inhibitory neuro-modulation with kava, lemon balm, valerian, and vitamin B-6.

Neuro-Modulation—Stimulating

Stimulating neurotransmitters help promote drive, ambition, alert mental functioning, and memory. They support a positive mental outlook by providing a feeling of energy and vitality. POSITIVE THOUGHTS supports stimulating neuromodulation with DMAE, L-phenylalanine, L-tyrosine, N-acetyl-L-tyrosine, and vitamins B-5 and B-6.

Neuro-Modulation—Balancing

In our high-powered, stress-filled world, the balancing properties of St. John’s wort can help maintain a positive outlook and a sense of well-being. Studies have shown that St. John’s wort can help support a positive mood.

Acetylcholine Production

Acetylcholine is one of the most important neurotransmitters in the brain. It is vital for memory, cognitive function, focus, concentration, and muscle movement. POSITIVE THOUGHTS contains DMAE, vitamins B-1, B-5 and B-12, and pantothenic acid to support acetylcholine production.

Energy Metabolism

The brain’s energy supports the vast electric, chemical, and structural processes that are the basis of a positive outlook. The brain uses 60% of the glucose used by the body at rest. Nutrients help convert glucose to the energy that the brain requires. They are also a component of many coenzymes needed for the synthesis of key neurotransmitters. POSITIVE THOUGHTS addresses energy metabolism with these nutrients: magnesium, manganese, zinc, vitamins B-1, B-2, B- 3, B-5, B-6, B-12 and C, biotin, and folic acid.

Strategies for WellnessSM: A Healthy Mood Plan

Lifestyle choices can help you maintain a positive ATTITUDE in response to the normal stresses of everyday life.

Neuro-Modulation—Inhibitory: GABA, Kava Kava, Lemon Balm, Taurine, Valerian, Vitamin B-6

Neuro-Modulation—Stimulating: DMAE, L-Phenylalanine, LTyrosine, N-Acetyl-L-Tyrosine, Vitamins B-5 & B-6

Neuro-Modulation—Balancing: St. John’s Wort

Acetylcholine Production: DMAE, Vitamins B-1, B-5 & B-12, Pantothenic Acid

Energy Metabolism: Magnesium, Manganese, Zinc, Vitamins B-1, B-2, B-3, B-5, B-6, B-12 & C, Biotin, Folic Acid

References:
Johnson, D. et al. (1994). J Geriatr Psychiatry Neurol:7 (suppl 1), S44-S46. Johnson, D. et al. (1992). TW Neurologie Psychiatrie:6, 436-444. Leathwood, P.D. et al. (1982). Pharmacology Biochemistry & Behavior:17, 65-71. Sabelli, H.C. (1986). J Clin Psychiatry:47(2), 66-70. Schulz, H. & Jobert, M. (1994). J Geriatr Psychiatry Neurol:7 (suppl 1), S39-S43. Wurtman, R.J. et al. (1974). Science:185, 183-184.

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VitaNet ® Staff

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Date: June 01, 2005 12:36 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Diet Phen - Dietary Supplement and weight Loss ...

Diet Phen for weight Loss

Getting slim, trim and fit is no easy task. To do it you need adequate Energy, Nutritional and Emotional Support, and a Positive ATTITUDE. Source Naturals puts them all together in the DIET-PHEN Weight Loss Plan. The plan includes an herbal-safe nutrient formula that combines optimal amounts of St. John’s wort with synephrine and green tea extract, plus L-phenylalanine and chromium. Meet your weight loss goals the natural way. Try Source Naturals DIET-PHEN dietary supplement in conjunction with the Diet-Phen Weight Loss Plan.

THE PLAN HELPS TO:

DIETING – It Starts in Your Head.

Successful dieting depends on the right mind-set: you need a positive outlook and determination. When your head is in the right place, your body may follow. That’s why the DIET-PHEN Weight Loss Plan includes natural herbs and amino acids to help support a sense of active calm.

ST. JOHN’S WORT – The CenterPeace of DIET-PHEN. In use since ancient times, Hypericum perforatum is a flowering herb highly valued for its positive influence on mental well-being. Known for its soothing effect, it seems to promote relaxation without drowsiness. Recent research has focused on the connection between hypericin (the principal phytochemical in St. John’s wort) and serotonin, a key neurotransmitter associated with mood. About 90% of your serotonin receptors are found in your brain’s emotional center, the limbic system.

SYNEPHRINE, GREEN TEA AND L-PHENYLALANINE – Energize with an ATTITUDE! Synephrine and green tea extract are added for that extra energy needed during dieting. The brain uses phenylalanine to manufacture dopamine and norepinephrine, two neurotransmitters that play an important role in drive and determination.

ACETYL L-CARNITINE – Transporting Fat to the Furnace. Within each of your trillions of cells are thousands of tiny energy factories called mitochondria. They convert fats and sugars into metabolic energy. Acetyl L-carnitine supports this process by transporting fat molecules to the mitochondria.

THE PLAN INCLUDES A DAILY SERVING OF 3 DIET-PHEN TABLETS TO PROVIDE:

GET STARTED WITH THE PLAN ! Get DIET-PHEN dietary supplements and the Weight Loss Plan at VitaNet health food store.

REFERENCES:

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VitaNet ® Staff

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Date: June 01, 2005 12:08 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Diet Metabo 7 -- It's all about Mood and Metabolism ...

Diet Metabo 7

It’s incredibly difficult to stay committed to a weight loss program—to change the eating habits of a lifetime and resist “emotional overeating.” You need a weight loss program that helps you break the unhealthful cycle of dieting and losing— followed by bingeing and gaining back.

We can’t stop the Yo-Yo®, but we can give you a fighting chance.

DIET METABO-7 supports seven body systems related to successful weight loss, including cellular energy generation and metabolism, and neurotransmitter production to support calmness, drive and determination.

DIET METABO-7 SUPPORTS SEVEN BODY SYSTEMS

Your body is composed of complex interactive systems that work on many levels. Likewise, the nutrients in DIET METABO-7 target specific body systems and the connections between them. This full spectrum nutritional formula helps instill balance and harmony by addressing seven interrelated systems whose healthy function is necessary for successful dieting: the brain and nervous system, metabolic energy, liver, thyroid, blood sugar levels, adrenals and fluid balance.

MOOD MANAGEMENT: A POSITIVE ATTITUDE

DIET METABO-7 can help you change your habitual response to eating and start making healthy food choices. A key strategy involves the production of neurotransmitters, the brain chemicals that regulate your nervous system. When certain neurotransmitter levels are low in your brain, you may feel depressed. You crave simple carbohydrates and sugars from bread, pasta or candy— because when the brain is low in mood-enhancing neurotransmitters, it does whatever it can to increase them. It will cause you to crave those foods that produce the building blocks your body uses to raise those neurotransmitter levels. DIET METABO-7 provides specific vitamins and amino acids necessary for your brain to make norepinephrine, serotonin, dopamine and GABA, the major neurotransmitters that help regulate mood and attention, support clear focus and active calm, and affect drive and determination. Included are the amino acids tyrosine, glutamine, phenylalanine and GABA. For example, the brain uses phenylalanine and tyrosine to manufacture norepinephrine. Increased amounts of norepinephrine can block the drive to eat and may help provide a sense of well-being.

METABOLIC ACTIVATORS: HERBAL ENERGIZERS

To support a sustained reduction of body fat, it’s helpful to increase metabolism via exercise and herbal stimulation while lowering caloric intake by curbing appetite. High doses of stimulants, however, are counterproductive and can make you nervous and irritable. To avoid being overly stimulative, DIETMETABO-7 is formulated with appropriate amounts of herbal metabolic activators that promote calorie burning and suppress appetite.

Used since ancient times in India to support health, Sida cordifolia contains a profile of naturally occurring ephedrine alkaloids that act as stimulants to promote the metabolism of fat. This thermogenic effect is augmented by the natural caffeine contained in standardized extracts of green tea, yerba mate, and kola nut. Also included are specific B vitamins essential to the production of energy from the breakdown of fats and carbohydrates.

HELPING THE LIVER: DETOXIFICATION AND CIRCULATION

One of the most overworked organs is the liver, the body’s chief manufacturing and detoxification plant. It constantly regulates the levels of chemicals circulating throughout the bloodstream and plays a key role in breaking down fat and eliminating waste products. The amino acid N-acetyl cysteine is an antioxidant that strongly supports liver function. Your liver needs it to make glutathione, a crucial detoxifying substance used to remove harmful compounds from your bloodstream. Optimal metabolic energy depends on healthy circulation, especially while dieting, when the bloodstream is delivering excess waste products to the liver for removal. To help maintain a healthy circulatory system, DIET METABO-7 includes standardized extracts of ginkgo and horse chestnut. In use for centuries, these botanicals have been the subject of numerous chemical and pharmacological investigations.

THE THYROID: YOUR BODY’S THERMOSTAT

Your thyroid gland produces hormones that control how quickly you burn calories and use energy. Tyrosine is an amino acid building block of thyroid hormones. Low blood levels of tyrosine have been associated with the underproduction of thyroid hormones. Kelp and bladderwrack provide natural sources of iodine, the basic substance of thyroid hormones.

STABILIZING BLOOD SUGAR: CONTROLLING MOOD SWINGS An important strategy of DIET METABO-7 is to minimize the changes in blood sugar levels that can cause unwanted mood swings, which diminish your physical and mental energy. Chromium, an essential mineral, is important to carbohydrate and fat metabolism and tends to increase insulin efficiency. It helps stabilize blood sugar levels and keep you on an even keel.

DEALING WITH THE STRESS FACTOR

Dieting often adds more stress to your life, and stress hormones affect the mind and body in many ways. They disrupt liver function and blood sugar levels, which lowers energy production in the brain, adversely influencing mood and motivation. Because your adrenals need extra attention, DIET METABO-7 helps nourish these hardworking glands with pantothenic acid and ascorbic acid, both necessary for healthy adrenal function. Also, pantothenic acid provides additional support for energy generation during dieting.

WATER BALANCE

Potassium is an essential mineral with many functions, including the transmission of electrical impulses in the brain. It works with sodium to control the body’s water balance. Dieting tends to deplete potassium levels in the body, therefore DIET METABO-7 replenishes this vital nutrient.

THE WEIGHT IS OVER

DIET METABO-7 provides necessary cofactors to balance body systems involved with healthy weight management. When used with the Maximum Metabolism Weight Loss Plan and exercise program, Source Naturals DIET METABO-7 may help you achieve your goal of a healthy and more vibrant life.

References
Astrup, A., Breum, L.,Toubro, S. November 1995. Pharmacological and clinical studies of ephedrine and other thermogenic agonists. Obesity Research. 3 Supp. 4:537S-540S. Baskaran, K. et al. October 1990. Use of Gymnema sylvestre (GS4)® leaf extract in the control of blood glucose ... Journal of Ethnopharmacology. 30(3):281-294. Ghosal, S., Ballav, R., Chauhan, P.S., Mehta, R. 1975. Alkaloids of Sida cordifolia. Phytochemistry. 14: 830-832. Singh, R. et al. 1994. Hypolipidemic and antioxidant effects of Commiphora mukul (gum guggul) as an adjunct to dietary therapy ... Cardiovascular Drugs and Therapeutics. 8:659-664.

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