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Alzheimer's Disease: What You Can Do to Prevent Holiday Memories from Vanishing Darrell Miller 11/26/17
America is about to realize just how poisoned conventional food really is ... Lab testing for glyphosate about to go 'viral' Darrell Miller 11/24/16
Is AHCC Good for the Immune System? How So? Darrell Miller 3/2/11
Calcium, Magnesium, Vitamin D Darrell Miller 8/6/08
ButterBur Extract Darrell Miller 6/5/08
Bilberry Extract Is A Powerful Antioxidant That Strengthens Veins Darrell Miller 4/12/08
Celiac disease Darrell Miller 4/8/08
Doctor’s Corner - Relora: Minimizes Stress-Induced Eating Darrell Miller 8/9/06
GAS CHROMATOGRAPHY-MASS SPECTROMETY (GC/MS) Darrell Miller 12/27/05
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (HPLC) Darrell Miller 12/27/05
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (HPLC) Darrell Miller 12/27/05
New Test for Early Cancer Detection Darrell Miller 10/18/05
Lowering cholesterol safely Darrell Miller 7/27/05
10 Things You Should Know About Prostate Cancer Darrell Miller 7/27/05
BLOOD TRANSFUSIONS Darrell Miller 7/15/05
Menopause Multiple - Eternal Woman Darrell Miller 6/3/05
Re: Sulforaphane Stimulates the Body's Cancer-Fighting Enzymes Darrell Miller 5/13/05




Alzheimer's Disease: What You Can Do to Prevent Holiday Memories from Vanishing
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Date: November 26, 2017 03:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Alzheimer's Disease: What You Can Do to Prevent Holiday Memories from Vanishing





Alzheimer's, like most diseases comes with its own set of problems, the memory loss being number one. Much like other diseases it is important to find those symptoms early. One easy way to help with that is mind exercises. These help with neuro plasticity and will allow your brain to function in top condition for years to come. Much like exercising works for the heart, muscles, and flexibility these exercises keep the brain healthy. Try them out!

Key Takeaways:

  • Getting an annual memory check up can help catch Alzheimer's disease in it's early stages.
  • A healthy diet, physical and mental exercise, and vitamin supplements can help improve your cognitive health.
  • The vital brain aging program can add many years of making happy memories, instead of forgetting them.

"Prevention and early detection of first signs of cognitive impairment and treating its cause is key to maintaining a healthy brain throughout life"

Read more: http://www.latimes.com/socal/daily-pilot/opinion/tn-dpt-me-commentary-shankle-20171122-story.html

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America is about to realize just how poisoned conventional food really is ... Lab testing for glyphosate about to go 'viral'
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Date: November 24, 2016 08:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: America is about to realize just how poisoned conventional food really is ... Lab testing for glyphosate about to go 'viral'





Do you ever really stop to think about what goes in your food and what you're putting in your body? Chances are that you probably don't, although there's a small minority of Americans that seems to. "America is about to realize just how poisoned conventional food really is ... Lab testing for glyphosate about to go 'viral'" talks about what's wrong with the food the average American eats, and how science has found a means to prove this.

Key Takeaways:

  • Our grandparentss food wasn't doused with chemical insecticides, herbicides, fungicides and other forms of pesticide that cause cancer, depression, central nervous system disorders, anxiety and dementia. Today, most grains and sugarcane get sprayed with disturbing amounts of glyphosate herbicide.
  • Good news! Anresco Laboratories in San Francisco just launched their own unique detection system for final food products that reveals even low levels of glyphosate residue, and they're testing soil samples from all around the world! Want food transparency? You got it.
  • First, buy certified organic food, grow your own food without chemicals, or buy from local farmers' markets and ask lots of questions of them. Second, look into buying a high quality water filtration system for your home. It's much cheaper in the long run than buying bottled water.

"There is no safe level that can be consumed, even though it's regularly found in American food and water."



Reference:

//www.naturalnews.com/055968_weed_killer_Roundup_glyphosate_testing.html

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Is AHCC Good for the Immune System? How So?
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Date: March 02, 2011 02:44 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Is AHCC Good for the Immune System? How So?

AHCC And Immune Health

Active Hexose Correlated Compound, or AHCC, is one of the most commonly used food supplements in Japan largely owing to its effective immune-boosting properties when successfully absorbed by the human body. The earliest important study concerning its activities in the immune system was published in the early 1990’s at Tokyo University, triggering a sudden rise in popularity among consumers in Japan, where it is sold over the counter.

Activates White Blood Cells

It has been observed in the past few years that AHCC boosts the immune system in many different ways in that it participates not only in the innate immune system but also in the adaptive immune system. Of special note is the significant increase in certain types of white blood cells, including natural killer cells, or NK, and macrophages. NK cells are in the employ of the innate immune system and responsible for the disposal of cells infected by viruses. They are often the first line of defense against common viruses such as herpes, containing the damage that viral infection spreads while waiting for specified mechanisms of the adaptive immune system. This is when macrophages come into play along with a cohort of lymphocytes. Their relatively bigger size allows them to effectively engulf pathogenic cells and the enzymes they contain break these pathogens down.

Removes Antigens and Toxins

AHCC also influences the production of antigen presenting cells, or APC. In a double-blind, placebo controlled study involving healthy individuals there was a significant increase in the quantities of APC, notably dendritic cells, in comparison with the baseline, and proteins released by lymphocytes called interferon. Both APC and interferon facilitate the detection of antigens and toxins created by invasive foreign bodies and alert the rest of the immune system of their presence. Dendritic cells are considered the most important group of all APCs in that they present a wide range of antigen presentation by way of phagocytosis or endocytosis, two different ways of catching antigens. By so doing, they make it easier for white blood cells to eliminate antigens and other toxic substances.

Defends against Cancer Cells

Cancer patients are the group of individuals that have benefited the most from AHCC. Early studies yielded data that are now being used to enhance the quality of life of those diagnosed with cancer. Indeed boosting the immune system has proven to play a part in the battle against cancer, and AHCC stimulates the immune system to manufacture a class of white blood cells that actively defend the body against cancer cells by causing tumor cells to die and on the same principle delay the proliferation of malignant cells.

There have been extensive clinical trials well underway in many countries, including China, South Korea, Thailand, Spain, and the US. These studies aim to that rigorously test its efficacy. In fact, AHCC belongs to the group of nutritional products tied to alternative medicine that has been supported by an abundance of data in connection with its safety and recommended dosages.

If you are battling disease, give AHCC a try.

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Calcium, Magnesium, Vitamin D
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Date: August 06, 2008 12:32 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Calcium, Magnesium, Vitamin D

Osteoporosis has always been known to threaten women, as it afflicts 8 million females in the US, but this bone-thinning disorder is becoming a serious public health issue among men also. More than 2 million men may be at risk for osteoporosis and bone fractures, with 6% of them over age 50 will experience a hip fracture as a result of this disease. Even though osteoporosis does not affect men as often as it does women, the risk for men increases with age, with the risk factors being similar to those of women. Osteoporosis often shows no symptom until a bone fracture occurs, which makes early detection extremely important.

With new bone material constantly replacing the old, more bone is produced than removed during childhood, which lets the skeleton grow. Bone mass peaks for most people during their 30s, with the processing reversing itself afterwards. The amount of bone slowly begins to decline as the removal of old exceeds the formation of new. Because female hormone production drops rapidly at menopause, this condition is immediately associated with increased bone loss. Hormonal changes in men occur much more slowly, with testosterone levels declining about 1% each year after the age of 40, remaining unnoticeable until after age 60.

Women lose bone more rapidly than men up until after age 65, when the rates equal out. The absorption of calcium decreases in both sexes, while excessive bone loss increases the fragility of bones, leading to fractures in the hip, spine, and wrist. Women begin to get spine fractures in their late 50s, while men take about 10 years longer for this to begin, which can partially be attributed to their larger skeletons, which takes longer for osteoporosis to develop.

Along with being brought on by advancing age and lower testosterone levels, osteoporosis can develop due to small stature, smoking, excessive alcohol intake, gastric cancer, HIV infection, celiac disease, various medications, and growth hormone deficiency. Because nothing can be done about one’s stature, some basic lifestyle adjustments, such as not smoking, limiting alcohol consumption to no more than two drinks each day, and increasing exercise, can help a man protect his bones. A man should also look for treatment for any other underlying medical conditions that affect bone health.

Calcium, one of the best known nutrients associated with healthy bones, needs help to provide maximum protection. Therefore, other skeleton-strengthening minerals necessary are magnesium, which regulates calcium transport within the body; zinc, which is required for collagen; and boron, which is a trace element that helps the body to use calcium, magnesium, and other minerals. Boron is also important because it activates vitamin D.

Finally, vitamin D is another key bone nutrient. In order to ensure adequate D intake, at least 10 minutes of sunlight a day or dietary supplements is important. In colder, cloudier times, vitamin D supplementation is highly recommended. Additionally, B vitamin deficiencies have often been associated with an increased chance of developing osteoporosis. The best way for a man to avoid osteoporosis is to be aware of his risk. The knowledge of osteoporosis in women has led to a downward trend in women breaking hips, but the incidence is still going up for men.



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ButterBur Extract
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Date: June 05, 2008 11:13 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: ButterBur Extract

An overactive bladder is a common complaint for pregnant women and men with enlarged prostates. Nearly 30 million people in the United States complain of incontinence. The problem is prevalent, yet can still be embarrassing. Even minor leaking can stop you dead in your tracks.

Pressure on the bladder makes it feel as if you always have to go to the bathroom. There is nothing worse than having to run to the restroom throughout the day, whether you are at work, at home or on a vacation. Making frequent pit stops is not in your best interest. Having an accident is worse.

Possible Bladder Problems

Bladder problems can occur in a number of ways. Be aware of these issues and don't be afraid to talk to your doctor to get help if you experience any of the following:

* Weak muscles that allow urine to leak
* Weak lining of the bladder that causes the urgency to urinate
* Obstruction of the flow of urine (often with an enlarged prostate)
* Bed-wetting
* Going to the bathroom more than eight times per day
* Getting up more than once per night with the strong urge to urinate
* Urinary tract infections
* Burning and irritation when you urinate
* Cloudy or bloody urine

Supporting a Healthy Bladder

There are some simple habits you can get into that will help support a healthy bladder. Consistency is the best policy to avoid potential problems down the line.

* Drink a minimum of eight glasses of water per day
* Relax when you are going to the bathroom; don't force it
* Cut back on caffeinated drinks
* Drink cranberry juice
* Eat healthy meals
* Get daily exercise
* Fully empty your bladder every time you urinate
* Talk to your doctor as needed; don't ignore problems

Create a Healthy Bladder with Butterbur

Butterbur is taken from the root of a purple flowering plant that has been used for fighting fevers, asthma, colds and urinary problems.

Butterbur is a supplement that supports healthy bladder functioning. It is an anti-spasmodic and anti-inflammatory. It works to relax the muscles of the bladder and reduce pressure. It is also good for liver problems, gastrointestinal disorders, kidney stones, ulcers, painful menstrual periods, and muscle spasms. Butterbur acts as a natural pain reliever, making bladder problems easier to handle.

People are becoming more reluctant to take prescription drugs for things like urinary tract infections. Antibiotics build up to the point where our bodies resist them and then no longer work. There are also unhealthy side effects that come with prescription drugs.

Naturally, this is leading more people to search for home remedies. Butterbur is an herb that can help relieve bladder problems without relying on an antibiotic. Of course, healthy habits that prevent urinary tract infections and other bladder problems are recommended. Early detection and treatment are in order when the bladder is not functioning well though.

Research shows that butterbur can reduce the sudden urge to urinate. It can restore the bladder to a healthy state and reduce your trips to the restroom. Make sure you are eating healthy foods, drinking cranberry juice, getting regular exercise and taking a butterbur supplement to relieve bladder problems.



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Bilberry Extract Is A Powerful Antioxidant That Strengthens Veins
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Date: April 12, 2008 11:06 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Bilberry Extract Is A Powerful Antioxidant That Strengthens Veins

Bilberry extract is taken from the Vaccinium myrtillus, or bilberry, a small blue berry that has been used traditionally for the treatment of conditions now known to be due to inflammation and the action of free radicals on the body.

Among these is atherosclerosis, or hardening of the arteries, caused by the free radical oxidation of the low density lipids that carry cholesterol around the bloodstream, and that cause deposition of fatty plaques on the arterial walls and eventually constricts them to a stage that can cause heart failure or a stroke, depending on whether the arteries are close to the heart or in the brain.

However, additional to treating this condition, bilberry has also traditionally been used for the treatment of varicose veins and also for certain eye conditions. In fact it was during the Second World war that the Royal Air Force in Britain received reports from pilots that their night vision improved after eating bilberries. Not only their vision, but the restoration of night vision after exposure to glare.

This was extremely important to war-time pilots who had to be able to rapidly adapt their vision to fly their plane after exposure to searchlights and explosive detonations. That is the reason for anything that appeared to promote this essential adaptation to be reported.

The pharmacology of these effects have been found to be due to the anthocyanosides in which bilberries are particularly rich. Anthocyanosides consist of an anthocyanaidin backbone, to which one of either arabinose, galactose or glucose can be bound. Since bilberry contains five of these anthocyanadins, then there are fifteen different anthocyanosides in the fruit concentrate.

The area of the retina that appears to control night vision, and the transition from day to night sight, is called the epithelium which is connected with purple vision. Anthocyanosides seem to have an affinity for this part of the retina, and in so doing plays an important part in this type of vision, specifically night vision although it is also beneficial in improving day vision.

Although bilberry also contains vitamins A and C, hydroquinone and tannins, it is the anthocyanosides that provide it with its unique antioxidant properties, and also its effect upon collagen fibers. It can cross-link collagen fibers to help overcome weaknesses in the connective tissues such as cartilage, tendons and the walls of blood vessels.

Its effect as an antioxidant is to prevent the cleavage of collagen by the cyzymes that are secreted by leukocytes generated by the immune system. By preventing histamine release, and release of prostaglandins and other proteins and cells mobilized during the immune inflammatory response to the detection of foreign invasion into human tissue, anthocyanosides can help to reduce inflammation and to protect against other extreme reactions of the immune system that can harm the organism it evolved to protect.

The most powerful property of anthocyanosides are their antioxidant properties: perhaps even its only property once all of the conditions it helps to protect against are fully understood. An antioxidant combines with free radicals and destroys them. Free radicals are particularly vile chemical entities that require an electron to make them stable, and they take this electron from the nearest source. This can result in oxidation and destruction of many bodily tissues leading to premature aging, atherosclerosis, eye damage and many other problems that result from the destruction of body cells and tissue.

The various constituents that make up bilberry act in concert to scavenge the free radicals and increase the supply of oxygen to the eye. The benefits of this are in helping to prevent cataracts and glaucoma, the latter due to the effect of the anthocyanoside cross-linking effect on the structure of the collagen in the eye. It can also help in cases of macular degeneration that affects the central area of the retina which might be due to the same property of there glucoside.

Moving away from the eyes and back to the vascular system, the collagen cross-linking properties of the flavonoids, which is what anthocyanosides basically are, can help to repair damaged vein tissue by strengthening the vein walls themselves, and also by providing support for the cell membranes, or outer layers of the cells.

This in turn builds up more strength in the vein tissue below the outside walls and contributes to an overall reduction in the weakness of the vein. This in turn enables it better to withstand the internal pressure put upon it by the failure of the valve that created the problem. In this way bilberries can be used to help repair the damage done by varicose veins and improve the function of the vein in returning blood to the heart from the extremities of the legs and also to help reduce the pain and swelling of varicose veins.

In addition to these beneficial effects on the vascular system and the eyes, bilberry can also help to decrease the permeability of the blood-brain barrier to pollutants, drugs and other undesirable chemicals by improving the resistance of the capillaries in the brain to the transfer of such substances through their walls. It does so by preventing the collagen of the capillaries in the brain being degraded either by enzymes or other agents, Also, by helping to strengthen that collagen structure so that it becomes more impermeable to the larger molecules that form the pollutants.

A lesser known constituent of bilberry is myrtillin, an anthocyanoside monoglucoside that is also available in all green plants, that possesses anti-glycemic properties. What this means is that it can reduce hyperglycemia and glycosurea, and so reduce blood sugar without reducing the blood sugar level to dangerously low levels. In other words it is an ideal insulin substitute.

Native Americans used green plants for teas for centuries and were free from diabetes until the came into contact with Europeans and adopted their dietary habits. Although the case has to be proved, it appears highly likely that it was the myrtillin that kept them free from a condition that affects so many other races.

Irrespective of that, however, it is for its powerful antioxidant effect that bilberry finds its best use, and also its effects on varicose veins. However, all of the above health benefits that bilberry provides, can likely be laid at the door of the combined antioxidant effect of its vitamin C content and the anthocyanosides – including the glucoside myrtillin.



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Celiac disease
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Date: April 08, 2008 11:58 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Celiac disease

Celiac disease also known as sprue, is an autoimmune disorder that often goes un-detection. It mimics the symptoms of other conditions including: irritable bowel syndrome, gastric ulcers, Crohn’s Disease, diverticulitis, parasitic infections, skin disorders, iron-deficiency anemia caused by menstrual blood loss, and various nervous system conditions. All of which are very uncomfortable for anyone to experience.

To complicate matters, between fifty to sixty percent of celiac patients have no obvious symptoms, which makes this disease particularly difficult to diagnose. This has led to the assumption that the disease was uncommon in the United States. However, recent estimates suggest that one in one hundred and thirty three people have the disease. Do you know if you have it?

In the Year 2000, a paper published in the Journal of the American Medical Association reported that the incidence of Celiac disease among 1200 children and adolescents tested for the disorder ranged from one in fifty seven to one in thirty three. Symptoms in children differ somewhat from those of adults in that fatigue, irritability and behavior changes are more common in children with Celiac disease. Infants with Celiac disease may lose weight and "fail to thrive."

Older children may have delayed growth or unexplained anemia due to malabsorption. Like adults, Celiac disease children have abdominal gas, pain and foul smelling stools. Liquid Supplements are recommended for individuals with Celiac's Disease.

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Doctor’s Corner - Relora: Minimizes Stress-Induced Eating
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Date: August 09, 2006 01:56 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Doctor’s Corner - Relora: Minimizes Stress-Induced Eating

Relora is a proprietary all-natural botanical product developed by Next Pharmaceuticals, Inc. it contains ingredients extracted from two plant species that have been used in traditional Chinese herbalism for over 1500 years. These are patented extract from Magnolia officinalis (US Patent No: US 6,582,735) and a patent-pending extract from Phellodendron amurense.

Relora helps relieve stress, anxiety and minimize stress-induced eating, which in turn may help to produce weight loss when used as part of a healthy diet and exercise plan. The research and development of Relora involved sophisticated testing and screening for ingredients that have anti-anxiety properties, but no daytime sedative effects. Initially, investigators tested the Magnoliaceae plant family as a lead source of new anti-anxiety products. Scientists first focused on two phytochemicals on constituents in the plant that have “bio-activity” (work positively on the body)—magnolol and honokiol. Through a series of studies, it became clear that Relora was a safe and effective formulation.

Relora works with the body’s natural chemistry to maintain normal levels of stress hormones. These hormones not only affect emotional well-being, but can also have a major impact on appetite and how the body stores and metabolizes fat. By working to re-establish a stable balance of these hormones, relora can help break the stress/weight cycle and restore optimum health to the mind and body.

In addition to normalizing stress hormones, Relora has been shown to control anxiety and the symptoms associated with it: irritability, emotional ups and downs, restlessness, tense muscles, poor sleep, fatigue and difficulty concentrating. Daytime sedation often occurs with products that induce relaxation. Not with Relora! This breakthrough botanical provides all the anti-anxiety benefits without inducing daytime sedation. In central nervous system receptor binding assays, the plant extracts in Relora bind to several important targets associated with anxiety. Also if interested, the bark of magnolia officinalis has been used in traditional Chinese herbalism for centuries for stress induced muscular tension.

Relora, Stress and Weight Loss

Stress is reported to play a significant role in a wide variety of health conditions. Recent work with the National Institutes of Health (NIH) and other major research centers has demonstrated that stress is a significant contributor to immune dysfunction, cardiovascular challenges, other age-related imbalances, and excess body fat. This type of fat is related to stress-induced hormone imbalances, especially imbalances of the hormones cortisol and DHEA. Until now, the only course of action for losing this fat has been stress reduction with exercise and diet, and anyone who has attempted diet and exercise alone often encounters a long, troublesome road. Relora may help the body normalize cortisol and DHEA levels in stressed individuals while inducing relaxation, and act as an aid in controlling weight and stress-related eating.

The increase in cortisol levels signals the brain that the body is in stress, causing food cravings, especially for high-fat, high-sugar foods. These foods, in turn, cause additional stress, thereby fueling the stress-cortisol cycle. Eventually, more fat is stored than the body needs unless sufficient exercise is in place to compensate, or the stress is reduced.

The ingredients in Relora are key supplements that help the adrenal glands to “come back to life” by reducing the excessive stress hormone response in the body and reducing carbohydrate craving behavior.

Results from Human Trials with Relora

Relora was tested at the Living Longer Institute in Cincinnati, OH and found to be safe, effective, rapid acting, non-sedating dietary supplement that helps control occasional mild anxiety. Three hundred forty five female subjects were administered Relora for 2 weeks. The dosage was 200mg of Relora three times daily. Eighty nine percent of the subjects reported that Relora helped them relax, while 78% found Relora to help prevent stress-related eating.

A second trial was undertaken at the Living Longer Institute to measure cortisol and DHEA levels in patients with mild to moderate stress. Elevated cortisol levels and depressed DHEA levels are associated with chronic stress. A two week regimen of Relora produced a significant increase in salivary DHEA (227%) and a significant decrease in morning salivary cortisol levels (37%). These findings support Relora’s ability to relieve stress and its potential role in weight control and stress-related eating behavior.

A third study was completed in late 2002 that evaluated Relora on its ability to improve snacking habits in people who snack on sweets or eat salty snacks when they are under excessive stress. Forty nine subjects were evaluated and it was found that Relora cur sweet snacking in the sweet cravers by 75%! It cut snacking on salty snacks by 50%. Seventy three percent of all individuals in the study reported feeling less stressed while taking Relora.

A double-blind placebo-controlled study was completed in January, 2004. forty premenopausal women were evaluated for stress, anxiety, food intake and weight management. Relora significantly reduced anxiety and prevented weight gain. A significant weight gain occurred in the placebo group while either now weight gain or weight loss occurred in the Relora group.

Suggested Use and Safety

Relora is designed for adults. The suggested daily dose is 1 capsule (250mg) 2 – 3 times per day. Relora is not recommended for persons under the age of 18. if you are pregnant, nursing or taking a prescription drug, consult a health practitioner prior to use.

Dr. James B. LaValle, R.Ph., N.M.D., C.C.N. is a licensed pharmacist (University of Cincinnati College of Pharmacy), certified clinical nutritionist (International & American Associations of Clinical Nutritionists), and doctor of naturopathic medicine (Central States College of Health Sciences, IAACN), with more than 18 years clinical practice experience in the field of natural therapeutics and functional medicine. Dr. LaValle is in clinical practice at the Living Longer Institute, a comprehensive wellness, prevention, and early detection program he co-founded. He sits on various scientific advisory boards within the dietary supplement industry. LaValle is also an adjunct professor in the college of pharmacy at The University of Cincinnati and serves as a preceptor in the Department of family Medicine, University of Cincinnati College of Medicine.

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GAS CHROMATOGRAPHY-MASS SPECTROMETY (GC/MS)
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Date: December 27, 2005 09:09 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: GAS CHROMATOGRAPHY-MASS SPECTROMETY (GC/MS)

GAS CHROMATOGRAPHY-MASS SPECTROMETY (GC/MS)

This cutting edge technology uses mass spectrometric detection in conjunction with gas chromatography. NOW® Foods mass spectrometer on GC is a highly sensitive ion trap detector (ITD). In this instrument, the eluted sample from GC is first ionized by electron impact or chemical method. Then the trapped ions are precisely ejected into an electron multiplier detector, and reported in mass-to-charge ratio. GC/MS has been used for the identification of compounds in natural and biological systems, such as characterization of unsaturated long-chain omega-3 fatty acids, the odor and flavor components of various products, and identification of pollutants such as pesticides.

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HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (HPLC)
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Date: December 27, 2005 09:08 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (HPLC)

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (HPLC)

HPLC is used to examine and verify potency claims on finished products and/or raw materials. For example, we use HPLC to measure the amount of active SAMe ion in our SAMe supplements, or the parthenolide content in organic feverfew herb. HPLC allows scientists to target and separate specific active ingredients from a solution by passing it through a sophisticated separation column combined with a mobile phase. The separated ingredients are then measured using ultraviolet light or other detection methods. Development of HPLC methods is a complex and precise science involving significant cost.

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HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (HPLC)
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Date: December 27, 2005 09:08 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (HPLC)

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (HPLC)

HPLC is used to examine and verify potency claims on finished products and/or raw materials. For example, we use HPLC to measure the amount of active SAMe ion in our SAMe supplements, or the parthenolide content in organic feverfew herb. HPLC allows scientists to target and separate specific active ingredients from a solution by passing it through a sophisticated separation column combined with a mobile phase. The separated ingredients are then measured using ultraviolet light or other detection methods. Development of HPLC methods is a complex and precise science involving significant cost.

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New Test for Early Cancer Detection
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Date: October 18, 2005 10:17 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: New Test for Early Cancer Detection

A new test for early cancer detection

Researchers out of Johns Hopkins University believe they may have found a new method of testing for cancerous growths that allows for much earlier detection. The new method of testing saliva and urine does not work for all cancers but would allow doctors to check for DNA abnormalities in these fluids. If these tests prove viable, they would allow for cancer detection years before symptoms appear.

Tests on patients suffering from cancers of the lung, voice box, mouth, throat and bladder showed 100 percent sensitivity to abnormal DNA particles. Researchers say that a mutation in the tumor guaranteed a detection in the bodily fluid.

The test works by detecting DNA strands that have been dumped by the tumor into the bloodstream and excreted by the body. These mutated DNA strands lead to dysfunctional cell division and give rise to tumor development and growth. In order to further test their theory, researchers tested a urine sample of the late U.S. Vice President Hubert Humphrey taken nine years before he was diagnosed with urinary cancer. The test showed the presence of DNA mutations.

Researchers are optimistic that these studies can push cancer detection up two, four or more years from its current position. New tests are being developed that search for more numerous DNA strands and are 200 times more sensitive than the original test. Major clinical research for these tests will begin next year.



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Lowering cholesterol safely
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Date: July 27, 2005 04:10 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Lowering cholesterol safely

Lowering cholesterol safely.

By Kim Vanderlinden, N.D., D.T.C.M.

Atherosclerosis and its complications are major causes of death in the United States and have reached epidemic proportions throughout all of the Western world. Heart disease accounts for 36% of all deaths among Americans and ranks as the number-one killer; stroke; another complication of atherosclerosis; is the third most common cause of death.

Foremost in the prevention and treatment of heart disease is the reduction of blood cholesterol levels. The evidence overwhelmingly demonstrates that elevated cholesterol levels greatly increase the risk of death due to heart disease. The first step in reducing risk for heart disease is keeping your total blood cholesterol level below 200 mg/dl (milligrams per deciliter).

Not all cholesterol is bad; it serves many functions in the body, including the manufacture of sex hormones and bile acids. Without cholesterol, many body processed would not function properly.

Cholesterol is transported in the blood by molecules known as lipoproteins. Cholesterol bound to low density lipoprotein, or LDL, is often referred to as the “bad” cholesterol, while cholesterol bound to high-density lipoprotein, or HDL, is referred to as the “good” cholesterol. LDL cholesterol increases the risk of heart disease, strokes, and high blood pressure, while HDL cholesterol actually protects against heart disease.

LDL transports cholesterol to the tissues. HDL, on the other hand, transports cholesterol to the liver for metabolism and excretion from the body. Therefore, the HDL-to-LDL ratio largely determines whether cholesterol is being deposited into tissues or broken down and excreted. The risk for heart disease can be reduced dramatically by lowering LDL cholesterol while simultaneously raising HDL cholesterol levels. Research has shown that for every one percent increase in HDL levels, the risk for a heart attack drops three to four percent.

Dietary cholesterol

Dietary cholesterol is a major risk factor in developing atherosclerosis. The evidence is substantial. However, several studies have shown that a lower dietary cholesterol intake was associated with up to a 37% lower risk of death from any cause, or an increased life expectancy of roughly 3.4 years.

Although dietary cholesterol intake is an important contributor to atherosclerosis, most of the cholesterol in the body is actually manufactured in the liver. Reducing dietary cholesterol alone is not always sufficient to lower blood cholesterol levels.

Common drugs

In an attempt to reduce blood cholesterol levels, many physicians are ignoring the need to give dietary recommendations and are instead utilizing drugs as the primary treatment. Using drugs before diet is clearly not the best approach, in terms of both effectiveness and cost. In fact, the Report of the National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of High Cholesterol in Adults clearly states: “Dietary therapy is the primary cholesterol-lowering treatment.”

The drugs lovastatin (Mevacor), prevastin (Pravachol), and simvastatin (Zocor) are commonly used to lower blood cholesterol levels. The main side effect of these drugs is liver damage. In fact, due to the seriousness of the possible adverse effects on the liver, it is necessary to have periodic blood tests to determine if the drug is harming the liver. Other side effects include: muscle breakdown, muscle pain, nausea, diarrhea, flatus, abdominal pain, headache, and skin rash.

Lowering cholesterol

The most important first approach to lowering a high cholesterol level is to follow a healthful diet and lifestyle. The dietary changes are simple: Eat less saturated fat and cholesterol by reducing or eliminating the amounts of animal products in the diet; increase consumption of fiber-rich plant foods (fruits, grains, and legumes); and lose weight, if necessary. Lifestyle changes include; Regular aerobic exercise; stop smoking; and reduce or eliminate consumption of coffee (both caffeinated and decaffeinated).

Here are the six key recommendations of U.S. Surgeon General, American Heart Association, and the National Research Council’s Committee on Diet and Health:


1. Reduce total fat intake to 30% or less of calories; reduce saturated fat intake to less than 10% of calories; reduce the intake of cholesterol to less than 300 mg daily.
2. Eat five or more servings daily of a combination of vegetables and fruits, especially green and yellow vegetables and citrus fruits.
3. Increase the intake of fiber and complex carbohydrates by eating sic or more servings daily of a combination of breads, cereals, and legumes.
4. Maintain protein intake at moderate levels
5. Balance food intake and physical activity to maintain appropriate body weight.
6. Limit the intake of alcohol, refined carbohydrates (sugar), and salt.

Natural alternatives

When there is a need for additional support to the dietary and lifestyle practices that can lower cholesterol levels, it simply makes more sense to use safer and more effective natural alternatives. When evaluating overall effectiveness, both LDL and HDL cholesterol levels must be taken into consideration. When you look at the cost, safety, and effectiveness, it is clear that natural alternatives are substantially superior to standard drug therapy.

Keep in mind that the natural alternatives discussed are, just like the dugs, still best utilized in a comprehensive program that stresses a healthful diet and lifestyle.

Niacin

Niacin, or vitamin B3, has long been used to lower cholesterol levels. In fact, niacin is recommended by the National CholesterolEducation Program as the first “drug” to use to lower blood cholesterol levels.

The safest form of niacin at present is known as inositol hexaniacinate. This form of niacin has long been used in Europe to lower cholesterol levels and also to improve blood flow. It yields slightly better results than standard niacin, but is much better tolerated, both in terms of flushing and, more importantm long term side effects.

Gugulipid

Gugulipid is the standardized extract of the mukul myrrh tree that is native to India. Several clinical studies have confirmed that gugulipid has an ability to lower both cholesterol and triglyceride levels. Typically, cholesterol levels will drop 14% to 27% in a four- to twelve-week period, while triglyceride levels will drop from 22% to 30%.

The dosage of gugulipid is based on its guggulsterone content. Clinical studies have demonstrated that gugulipid extracts standardized to contain 25 mg of guggulsterone per tablet given three times per day is an effective treatment for elevated cholesterol levels, elevated triglyceride levels, or both.

Garlic and onions

Garlic and onions exert numerous beneficial effects on the cardiovascular system, including lowering blood lipids and blood pressure. Numerous studies have demonstrated that both garlic and onions are effective in lowering LDL-cholesterol and triglycerides while simultaneously raising HDL-cholesterol levels.

Final Comments

Without question, the best approach to lowering cholesterol levels is through diet and lifestyle modifications. When additional support is require, there are safer and more effective natural alternatives to commonly prescribed drugs.

The goal of therapy, whether natural or synthetic, is to get blood lipid levels down into target ranges as quickly as possible. Once the target range has been achieved, begin reducing the amount of medicine by half, or take it every other day. Recheck your cholesterol levels in one month. If they have stabilized or continued to improve, you may no longer need the medication. If the levels begin to rise again, return to previous dosage.

If you are currently on a cholesterol-lowering drug, you must consult your doctor before discontinuing the medication.



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10 Things You Should Know About Prostate Cancer
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Date: July 27, 2005 02:12 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: 10 Things You Should Know About Prostate Cancer

10 Things You Should Know About Prostate Cancer

If you were to compile a top ten list of things men would rather just avoid, prostate exams might even rate above taking out the garbage, doing dishes and going shopping. But there’s no good excuse to ignore this walnut-sized gland located between the bladder and the penis and in front of the rectum. Confused by the debate surrounding nearly ever aspect of prostate cancer and embarrassed to request a physical exam, many men ignore prostate health, only to discover that the benefits of screening far outweigh its risks. As women openly talk about breast and ovarian cancers, prostate health remains a difficult and controversial topic for men to discuss, forcing many to forgo the manual exam that could lead to early detection and straightforward treatment. Though most males eventually develop some cancerous cells in their prostates, many prostate cancers develop so slowly that men often die of other causes. Indeed, it’s often said that most men die with prostate cancer, not from it. But the fact remains that prostate cancer kills more men who don’t smoke than any other cancer: The American Cancer Society reports that more than 232,000 men will be diagnoses with prostate cancer in 2005 and 30,350 will die from it. These statistics seem fairly overwhelming when you consider that one in six men will be diagnosed with prostate cancer in his lifetime, while one in eight American women will develop breast cancer in her lifetime. Despite the ongoing debate about whether the results of a prostate screening may cause unnecessary treatment, growing evidence suggests that testing for prostate cancer saves lives. The number of men who died of the disease fell by 26% from 1991 to 2001, with a five-year survival rate for men diagnosed with early-stage prostate cancer of nearly 100%; 10-year survival rates for all prostate cancer patients stand at 92%, while 15-year survival rates fell to 61%. Energy Times evaluated some of the key issues surrounding prostate cancer, including screening misconceptions, risk factors and lifestyle choices that can influence the likelihood of developing this potentially deadly disease. We hope they help you, or your significant other, make well-informed health decisions.

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BLOOD TRANSFUSIONS
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Date: July 15, 2005 09:33 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: BLOOD TRANSFUSIONS

BLOOD TRANSFUSIONS

With the increasing rates of several blood-carried diseases (like AIDS), blood transfusion and blood donation rates are declining. Ensuring that donated blood is not “contaminated” by disease dictates that fewer people can donate blood, while fear of being contaminated by blood tainted by blood usually dissuades physicians from requiring blood transfusions unless absolutely necessary. Finding some sort of treatment of tainted blood would not only save money and time, but also calm fears about the possibility of being infected with a potentially serious disease through a blood transfusion. Hypericum is showing great promise in being able to treat blood contaminated by viruses. A recent Transfusion study states, Since hypericin is devoid of adverse action in most blood components and blood analyses, it is investigated as an additive with potential to inactivate infective viruses in blood components intended for transfusion. . . . Complete inactivation of 10 (6) tissue culture-infective doses of human immunodeficiency virus was obtained in whole blood and in diluted packed red cells after illumination with fluorescent light for 1 hour. Loss of viral infectivity to cultured CEM cells has been monitored by use of a detection assay for human immunodeficiency virus p55 in enzyme-linked immunosorbent assay and cytopathic assays. In physiologic media, hypericin interacts with albumin and lipoproteins, retaining the virucidal activity in bound form. . . . The apparent transfusibility of hypericin, taken together with the efficacy of the virucidal activity, the broad range of enveloped viruses affected, and the absence of adverse effects on stored red cells, may render hypericin useful for inactivation of infectious viruses in red cells.24

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Menopause Multiple - Eternal Woman
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Date: June 03, 2005 05:54 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Menopause Multiple - Eternal Woman

Menopause

Menopause happens to all women, but affects each woman uniquely. For some, the end of fertility (and the end of concerns about contraception) brings a sense of freedom. For others, it is a time of troublesome symptoms or perhaps the need for certain lifestyle adjustments. Menopause is a bridge to a point in life when many women report feeling more confident, empowered and energized than in their younger years. MENOPAUSE MULTIPLE is a Bio-Aligned Formula™ that helps bring alignment to a range of interrelated body systems: hormonal regulation, bone metabolism, cardiovascular health, energy generation and circulation.

After menopause, the ovaries no longer secrete two critical steroid hormones in the amount or pattern characteristic of a regular menstrual cycle. These two hormones are estrogen and progesterone. The transition from regular ovarian function to its absence is often called the perimenopause or perimenopausal transition. The time involved can range from one to 10 years. More than one third of the women in the United States, about 36 million, have been through menopause. With a life expectancy of 81 years, a 50-year-old woman can expect to live more than one third of her life after menopause. Low estrogen levels are linked to some uncomfortable symptoms in many women. The most common and easy to recognize symptom is hot flashes -- sudden intense waves of heat and sweating. Some women find that these hot flashes disrupt their sleep, and others report mood changes. Other symptoms may include irregular periods, vaginal or urinary tract infections, urinary incontinence (leakage of urine or inability to control urine flow), and inflammation of the vagina. Because of the changes in the urinary tract and vagina, some women may have discomfort or pain during sexual intercourse. Many women also notice changes in their skin, digestive tract, and hair during menopause. Because the menopausal years place unique nutritional demands on a woman’s body, Source Naturals created MENOPAUSEMULTIPLE. This comprehensive formula brings together optimal amounts of the finest phytonutrients and herbs--including genistein, black cohosh, and chaste berry--plus vitamins and minerals known to support the biochemistry of mature women.

Bio-Aligned Formula™

MENOPAUSE MULTIPLE is a comprehensive herbal-nutrient formula that supports the multiple, interconnected systems involved with female hormone function.

Hormonal Regulation

Hot flashes are related to hormone levels. As estrogen declines, FSH and LH (folliclestimulating and luteinizing hormones) increase, causing blood capillaries to dilate. This brings more blood and higher temperatures to the skin. Soy isoflavones and other herbs can mimic the effects of estrogen. Support for the adrenal glands is important since they account for most estrogen production after menopause.

Musculoskeletal System

During and after menopause, a woman’s hormonal balance and biochemistry change. Lower estrogen levels may affect bone density. Phytonutrients and calcium are important to maintain healthy bones in postmenopausal women. Calcium and magnesium work together in the metabolism of bone.

Heart & Circulation

Menopause increases concern for the health of the heart and circulatory system. Soy isoflavones and other ingredients may help maintain healthy cholesterol levels. To regulate homocysteine levels for cardiovascular health, vitamins B-6, B-12, and folic acid are critical.

Liver Support

Among its many functions, the liver has the important job of promoting hormonal balance by processing excess levels of hormones. The powerful antioxidant, N-acetyl cysteine, helps the liver detoxify chemicals and milk thistle is a liver protectant.

Energy Generation

The fatigue that is common during menopause makes nutritional support for energy and metabolism especially important. Metabolism can influence weight, energy levels, and mood. MENOPAUSE MULTIPLE contains ingredients that support energy generation, including the advanced nutrients CoQ10 and lipoic acid and ginkgo biloba.

Antioxidants: Anti-Aging

Antioxidants help protect the circulatory system, which is important as estrogen declines. Antioxidants also defend tissues and cell membranes in all your body systems from free radicals, which are formed during normal cellular metabolism. Some important antioxidants: vitamin E, vitamin C, selenium, zinc, and manganese all have strong antioxidant powers.

Lifestyle Tips for a Healthy Transition

Get Moving. Exercise is a powerful remedy for many menopause complaints and may help prevent future menopause-related diseases. It promotes better, more restorative sleep, and it stimulates production of endorphins, or “feel good” brain chemistry. Some women report having fewer hot flashes when they exercise regularly. Eat Well. A balanced diet low in saturated fat and high in whole grains, fruits and vegetables, with adequate water, vitamins and minerals contributes to good health. Women at perimenopause and beyond have special dietary concerns, because both heart disease and osteoporosis are greatly affected by diet. A balanced diet is also important for bone development and maintaining bone strength. Some women – especially those who are elderly and have reduced appetites, who diet frequently, who don’t consume diary products, or who have eating disorders – may not consume adequate vitamins and minerals to maintain optimal bone mass. There is evidence that the natural, estrogenlike compounds in soybeans and many other plant foods used in MENOPAUSE MULTIPLE may reduce hot flashes and vaginal dryness and increase bone density in women after menopause. Studies suggest that body cells respond to plant estrogens as if they were weaker versions of the human hormone. So consuming more of these estrogen-mimicking compounds may help compensate for the loss of estrogen naturally as women age. Prevent Bone Loss. Osteoporosis is one of the most preventable of bone diseases. Exercise maintains the strength of bones through aerobics, stair climbing, hiking, or walking. Prevention focuses on nutrition for bones, including a sufficient calcium intake of 1000 to 1500 mg/day.

Musculoskeletal System: Black Cohosh, Dong Quai, Licorice, Soy Isoflavones, Boron, Calcium, Magnesium, Manganese, Vitamins A, B-6, B-12, C, D & E, Folic Acid

Heart and Circulation: Black Cohosh, Coenzyme Q10, Dong Quai, Licorice, Soy Isoflavones, Magnesium, Vitamins B-6, B-12, & E, Folic Acid

Hormonal Regulation: Black Cohosh, Dong Quai, Licorice, Soy Isoflavones, Vitex, Vitamins B-5 & C

Liver Support: Coenzyme Q10, N-Acetyl Cysteine, Dandelion, alpha-Lipoic Acid, Silymarin, Selenium, Vitamin C, Biotin

Antioxidant Defense: Coenzyme Q10, N-Acetyl Cysteine, alpha-Lipoic Acid, Silymarin, Selenium, Zinc, Vitamins A, C & E

Energy Generation: alpha-Lipoic Acid, Coenzyme Q10, Magnesium, Manganese, Zinc, Vitamins B-1, B-2, B-5, & B-6, Niacinamide

References
Abraham, G.E. & Grewal, H.G. 1990. JRM, 35:503. Anderson, J.W., et al. 1995. The New England Journal of Medicine, 335(5): 276-82. Avioli, L. V. (1993). Calcium and Bone: Myths, Facts and Controversies in the Osteoporotic Syndrome: Detection, Prevention and Treatment, 3rd ed. (Avioli ed.) New York: Wiley-Liss. Christy, C.J. 1945. American Journal of Obstetrics & Gynecology, 50:45. Colborn, Theo. 1996. Our Stolen Future. New York: Dutton. Murkies, A.L., et al. 1995. Maturitas, 21:189-95. Nielsen, F.H., et al. 1987. FASEB J, 1:394-97. Raines, E.W., & Ross, R. 1995. Journal of Nutrition, 125:624S-30S. Tranquilli, A., et al. 1994. Gynecological Endocrinology, 8(1):55-8.



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Date: May 13, 2005 08:38 AM
Author: Darrell Miller (dm@vitanetonline.com)

Sulforaphane Stimulates the Body's Cancer-Fighting Enzymes

Secret Weapon Against Cancer Found in Broccoli Sprouts

by Richard Conant, L.Ac, C.N.

The health benefits of vegetables were known historically, long before researchers began seeing a connection between vegetable consumption and cancer prevention. Over the last twenty years, evidence concerning this connection has steadily accumulated. The latest and most promising findings reveal that specific vegetable constituents—"phytochemicals" to use current scientific parlance— enhance the body's defenses against cancer.

This article will focus on one phytochemical in particular, a sulfur-containing compound called "sulforaphane." Found in Cruciferous vegetables such as broccoli, sulforaphane may prove to be one of our most powerful cancer prevention allies. Recent studies have shown that sulforaphane stimulates, or "induces," "Phase two enzymes." These enzymes are an integral part of the body's elaborate detoxification system that renders carcinogens inactive. This detoxification system turns carcinogens and other toxic substances into harmless molecules that are excreted from the body.

We need not fear carcinogens—the body is equipped to deal with them.

These findings, coupled with an appreciation of the body's ability to defend itself against carcinogens, have the potential to dramatically change the way we look at cancer and substances in the environment that "cause" cancer. We need to minimize unnecessary exposure to carcinogens, and the staggering quantity of hazardous chemicals in the environment remains an urgent health concern, for cancer and many other health problems. But, knowing the body is equipped with the means to defend itself against toxins, we do not need to fear carcinogens as perhaps we have in the past.

The natural world is full of carcinogens.

What's more, even if you eat 100 percent organic food and live in a environment free of toxic man-made chemicals, you are still being exposed to carcinogens every day of your life. Food is the primary route of this exposure. Plants, for their own defense, produce over 99% of all the pesticides in agricultural products.1 Almost all foods—in their natural state—contain tiny amounts of naturally-occurring, potentially carcinogenic chemicals.

The point is not to trivialize the concern over environmental toxins. The point is that the natural world is full of toxins that are not man-made. These substances have been around since before we appeared, which is why we have evolved with a highly efficient system for neutralizing them before they can damage our cells and initiate the complex process that produces cancer.

Broccoli sprouts are a concentrated source of cancer-fighting sulforaphane.

We cannot avoid carcinogens. What we can do is support our internal detoxification system. Sulforaphane is a powerful tool in this effort. We can start by following the often-repeated advice to eat a variety of vegetables every day, and include broccoli in our menu.

There is an even richer source of sulforaphane than broccoli itself. In September 1997, a group of scientists at the Johns Hopkins University School of Medicine made a breakthrough discovery— broccoli sprouts contain ten to one hundred times more sulforaphane than mature broccoli.2 Vegetable sprouts are generally regarded as exceptionally healthy foods. Broccoli sprouts now look like a shining star, especially when it comes to cancer prevention.

For those lacking the time or inclination to keep a fresh supply of broccoli sprouts on hand, broccoli spouts have been processed into an extract that is even more concentrated in sulforaphane. More on this later.

What have researchers learned about broccoli consumption and cancer rates?

More than 200 epidemiological studies—studies which track groups of people over time to uncover realtionships between variables such as diet and the incidence of disease—have invesitgated the connections between vegetable consumption and various forms of cancer.1 It should be understood that findings from epidemiological research are generally not regarded as conclusive; these studies are not controlled, and often use data gleaned from questionnaires, which are an imprecise method of gathering information. (In the case of diet questionnaires, for example, the study subjects may or may not record their food intakes with 100 percent accuracy.)

Epidemiological studies look for trends. To be credible, these trends need to show up consistently, in different population groups. Findings from the vegetable intake/cancer studies easily meet these criteria; the number of studies is large and the trend is consistent—vegetable consumption is strongly associated with a lower risk of developing cancer.

What about broccoli in particular? A paper published in the September 1996 issue of Cancer Epidemiology, Biomarkers & Prevention analyzes epidemiological data gathered from 94 studies concerning the cancer preventive effect of brassica vegetables.3 (The Brassica genus, part of the Cruciferae family, includes broccoli, cabbage, kale, cauliflower and brussels sprouts.) The data suggest that broccoli consumption reduces the risk of some of the most feared forms of cancer, including stomach and lung cancer.

Now, to put these data into a balanced perspective, the researchers point out that in most of the studies reviewed, brassica vegetable consumption was reported as part of the total vegetable intake. "In hardly any epidemiological studies was the effect of brassica vegetables separated from the effect of total vegetables or other vegetables by adjusting for consumption of these variables. Therefore, it is difficult to sort out whether the observed observation was attributable to brassica vegetables, to vegetables as a whole, or to other vegetables," they noted.

This uncertainty is a good example of why epidemiological studies alone do not give us open and shut conclusions. But the paper also adds that the apparent anti-cancer effect of brassica vegetables agrees with "the results of experimental studies in which brassica vegetables reduced mammary tumor incidence, hepatic tumor size, numbers of tumors per liver, tumor frequency, and the number of pulmonary metastases when given to rodents before or after a carcinogen insult."3

When you put together a plausible trend from epidemiological research with results of experimental studies that agree with the trend, and then add additional research that reveals the underlying mechanism for these observations, a clear picture begins to take shape. And, indeed, we now have a fairly good idea as to just how brassica vegetables, especially broccoli, help prevent cancer.

How sulforaphane helps prevent cancer from developing.

To see how sulforaphane works, let's look at a brief overview of the body's detoxification system.

The detoxification of carcinogens and other toxic substances takes place in the liver, and involves two distinct enzyme-driven processes or "phases". Phase one enzymes neutralize toxins by various routes. Some of these convert toxins into substances that are immediately eliminated. However, other Phase one steps convert toxins into intermediate products which are carcinogenic themselves, and require further treatment before they can be excreted. Phase two enzymes do this vital job. Phase two enzymes deactivate these carcinogenic metabolites of Phase one, and the final breakdown product is then eliminated once and for all. (For an excellent review of this subject, see Encyclopedia of Natural Medicine, by Drs. Michael Murray and Joseph Pizzorno.4)

Phase two is critical. If Phase one is in good working order, but Phase two is not, the potential threat from carcinogens increases. It is vitally important to keep Phase two operating well. This is where sulforaphane plays its cancer preventive role. Sulforaphane is a powerful inducer of Phase two enzymes.5,6

Broccoli sprouts-the ideal source of sulforaphane

Sulforaphane is one among a group of phytochemicals called "isothiocyanates." (These occur in brassica vegetables largely as "glucosinolates," which are precursors for isothiocyanates2,12 When the plant is crushed, glucosinolates are converted to isothiocyanates.) Sulforaphane induces Phase two enzymes exclusively, leaving Phase one enzymes alone. This means it helps reduce the load of carcinogenic Phase one intermediates without adding to the load by stimulating Phase one.8,9

As reported by the Johns Hopkins University research group, broccoli sprouts are an "exceptionally" rich source of sulforaphane (in the form of "glucoraphanin, sulforaphane's glucosinolate precursor). And broccoli sprouts have another advantage over mature broccoli. They contain almost no indole glucosinolates, phytochemicals present in mature broccoli that "can enhance tumorogenesis."2

Broccoli sprouts as an extract, now available as a dietary supplement, takes the concentration of sulforaphane to the next level. This recently developed nutraceutical product contains a potent 20 to 1 extract of three-day old fresh broccoli sprouts.

One 125 mg capsule supplies the same amount of sulforaphane as 125 grams, or about 5 ounces, of mature broccoli. Taking just one capsule a day is like eating two pounds of broccoli per week, which equals the intake of cruciferous vegetables believed necessary to obtain their health benefits.

References

1. Steinmetz, K.A. Potter, J.D. Vegetables, fruit, and cancer prevention: A review. J Am Diet Assoc. 1996;96:1027-1039.

2. Fahey, J.W., Zhang, Y., Talalay, P. Broccoli sprouts: An exceptionally rich source of inducers of enzymes that protect against chemical carcinogens. Proc. Natl. Acad. Sci. 1997; 94:10367-10372.

3. Verhoeven, D.T.H., et. al. Epidemiological studies on brassica vegetables and cancer risk. Cancer Epidemiology, Biomarkers & Prevention 1996;5:733-48.

4. Murray, M. Pizzorno, J. Encyclopedia of Natural Medicine. Rocklin, CA: Prima Publishing;1998:110-120.

5. Zhang, Y. Talalay, P, Cho, C., Posner, G.H. A major inducer of anticarcinogenic protective enzymes from broccoli: Isolation and elucidation of structure. Proc. Natl. Acad. Sci. 1992;89:2399-2403.

6. Gerhäuser, C. et. al. Cancer chemopreventive potential of sulforamate, a novel analogue of sulforaphane that induces phase 2 drug-metabolizing enzymes. Cancer Research 1997;57:272-78.

7. McDanell, R., McLean, A.E.M., Hanley, A.B., Heaney, R.K., Fenwick, G.R. Chemical and biological properties of indole glucosinolates (glucobrassicins): A review. Fd. Chem. Toxic. 1988;26(1):59-70.

8. Talalay, P. Mechanisms of induction of enzymes that protect against chemical carcinogenesis. in Advances in Enzyme Regulation, Vol. 28, Weber, G., Ed., 1989: Pergamon Press.

9. Prochaska, H.J. Santamaria, A.B., Talalay, P. Rapid detection of enzymes that protect against carcinogens. Proc. Natl. Acad. Sci. 1992;89:2394-98.

  • Broccoli Concentrate 850mg 60tb
  • Broccoli Seeds Sprt 4 oz.
  • Broccoli Sprouts 30tb
  • Broccoli Sprouts 60tb
  • Indol 3 Carbinol from Broccoli 30ct 100mg
  • Indol 3 Carbinol from Broccoli 30ct 25mg
  • Indole 3 Carbinol 200mg 30ct from broccoli


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