Search Term: " Ester-C "
Vitamin C FAQ's
December 27, 2005 05:11 PM
Vitamin C FAQ's
What is Calcium Ascorbate?
Calcium Ascorbate is a buffered salt (mineral) form of the water-soluble antioxidant Vitamin C (ascorbic acid). Calcium is reacted with ascorbic acid to buffer the acidic nature of this vitamin, making it more gentle for the special needs of those who may have a sensitive gastrointestinal tract. The pH of this buffered mineral Ascorbate is approximately 6.8—7.4 as compared to ascorbic acid that is about a pH of 2.5. Calcium Ascorbate provides approximately 10% elemental calcium.
What does Calcium Ascorbate do?
Ascorbate (vitamin C) is a reducing sugar (has a reactive ene-diol structure) that is involved in biochemical processes such as hydroxylation of proline and lysine utilized in the formation of collagen and healthy connective tissue. A deficiency in Ascorbate results in a disease called scurvy which manifests as weakened collagen fibers, rotting teeth, delayed healing and open sores on the skin. Ascorbate is involved in many other vital functions such as the mobilization of iron, stimulation of immune system and as an anti-oxidant for scavenging of reactive free radicals.
Is this a necessary vitamin or can our bodies make enough to satisfy our needs?
Many plants and animals do not need to consume foods high in ascorbic acid to meet their need for Vitamin C because they are genetically programmed to produce enzymes that convert glucose into ascorbic acid. Unfortunately humans have only 3 of the 4 enzymes necessary for internal production of ascorbic acid, therefore we must satisfy our physical needs for this important vitamin through our intake of foods rich in vitamin C and/or take a good supplement.
What is the function of the Citrus Bioflavonoids?
Bioflavonoids are biologically active Flavonoid compounds found throughout the entire plant kingdom. Since the discovery of Flavonoids in 1936 when they were first isolated from lemons and called citrin and Vitamin P over 4,000 different types have been characterized. Though there are several forms of Bioflavonoids in the complex the predominant form is Hesperidin. These Flavonoids exhibit beneficial effects on capillary permeability and therefore support blood flow. They are antioxidants that work synergistically with Vitamin C as well as exhibiting anti-inflammatory activity.
Why are there color variations in your different Vitamin C products, and are they safe to take?
Most natural Vitamin C products vary in color from batch to batch and bottle to bottle. There are normally variations in the color of the raw material used during manufacturing, which is a normal occurrence. This is due to natural color variations in the source of the Vitamin C – generally, you will find C supplements to range in color from a light tan color to a light gray color.
Over the course of the shelf-life of a Vitamin C supplement, oxidation can cause a slight change in color, so you may find the light tan C-1000 you bought has changed to a darker tan six months later. This is a normal occurrence, and the product is safe to use up until the expiration date, and even beyond. NOW® is generally conservative with expiration dates, so a Vitamin C product is still safe after the date, it just may not be as effective due to oxidation.
Why does your Ester-C Complex say 625mg on the front of the label but list 500mg on the Supplement Facts panel? The key word is “complex”. Ester-C Complex is a combination of ascorbic acid (natural Vitamin C) and Calcium Ascorbate, which ultimately yields 500 total mg of Vitamin C. It is complexed with Calcium Ascorbate and other metabolites for greater absorption and faster utilization by your body. So the total complex is 625mg of Ester-C Complex, which yields 500mg of natural Vitamin C as ascorbic acid.
NOW Ester-C Pure Powder states the serving size is ½ teaspoon. How much Vitamin C am I getting with this serving size? ½ teaspoon of Ester-C Pure Powder is equivalent to 2000mg of natural Vitamin C and 250mg of Calcium.
Can I pour the powder in NOW® Vitamin C capsules into a liquid instead of swallowing the capsule? Many people do not want to or cannot swallow capsules, tablets or softgels, for various reasons. Encapsulated Vitamin C products from NOW® can be opened and dumped into a liquid for consumption. Juice or water is recommended if you choose this method. However, taking Vitamin C with water on an empty stomach is the recommended method of ingestion. We do not recommend trying this method with Vitamin C in tablet form, although you can grind or smash a tablet into powder form and add to water or juice. If you choose to do this, use a mortar and pestle for best results and minimal loss of product. Why go through the trouble when NOW® carries Vitamin C in a powdered form already. Save yourself time and trouble by ordering this form instead. Disclaimer: This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Now Foods -QUALITY- High Standards and Attention to Detail
December 27, 2005 09:00 AM
QUALITY “High Standards and Attention to Detail”
As you shop for dietary supplements you’re faced with an almost dizzying array of choices. Naturally, every product claims to be this, that and the other. But you’ve heard the stories in the media of products that don’t live up to their claims. So how do you know who’s telling the truth? Perhaps a better gauge of a product’s quality is the manufacturer and their history. Do they have a legacy of producing quality goods? How long have they been in business? Is their track record good or do they have a history of product recalls and bad press? If you’re responsible for your family’s health and well-being, it pays to do your homework when it comes to the products you purchase for them. NOW® Foods has been manufacturing dietary supplements and whole foods for 35 years.
Companies that thrive and continue to grow for this long don’t do so because they produce poor quality products. They do so by maintaining extremely high standards and paying special attention to every detail, which is the secret to product quality. At NOW® Foods, these high standards and attention to detail are evident in every aspect of our operations, from receiving to production to finished goods, just as they have been for 35 years. You’re committed to buying only the best for your family, and we’re committed to supplying only the best for our customers.
Quality products are made using the highest quality ingredients. NOW Foods purchases raw materials from only the most reputable vendors, who are required to provide detailed specification sheets and lot-specific certificates of analysis for every shipment we receive. These documents provide information on the quality of the raw material and the various analyses used to verify that quality. Shipments that do not meet our quality standards are sent back to the manufacturer with a point by point report card of why the shipment was refused. We simply don’t just accept every shipment that’s delivered to our dock – no ingredient gets a free pass into our production facility. In addition, we also perform random vendor audits throughout each year to ensure that they’re meeting our stringent quality standards. NOW ® Foods is always vigilant when it comes to quality, just as you are. Another way we maintain high quality standards is by choosing to buy and incorporate registered and/or trademarked ingredients into our products. Each of these ingredients are exclusively produced by a company that owns proprietary manufacturing rights and licenses selected companies like NOW® to use these top quality ingredients in their products.
These registered/trademarked ingredients must undergo even more rigorous analysis and controls than other ingredients, and so offer additional assurance that products containing them are properly manufactured and labeled. Additionally, to maintain the integrity of their ingredient’s reputation, the trademark owner will independently test finished products from manufacturers to verify the quality meets their standards and the label claim of the company licensed to use it. You may be familiar with some of the trademarked ingredient NOW® uses such as, Ester-C® vitamin C, Chromemate® Chromium and L-Carnipure® Carnitine.
Scientific analysis of ingredients is extremely important to ensure the integrity of any dietary supplement. NOW Foods has made substantial investments in the development, construction and staffing of numerous inhouse laboratories, including an advanced instrumental analysis laboratory, a “wet lab” and a state-of-the-art microbiology lab. This saves us the time and expense of having to send samples out to commercial labs for analysis. While we use independent labs to verify our in-house test results, our capabilities allow us greater control over product quality and quicker approval of raw material shipments for production, which means fresher products for consumers. Our investment ensures that NOW® will be able to meet ever-increasing demands for accurate product analysis and outstanding product quality. NOW® is unique in the industry in that we annually spend more on Quality Assurance & Control than we do on Marketing and Advertising combined. What good is a lab without qualified people? NOW® employs an expert team of highly qualified scientists and technicians, including four Ph.D.’s. They’re constantly working to develop new and improved analytical methods, and their efforts contribute not only to our product quality but that of the entire industry as well.
This is all great, you say, but what about your facility and the equipment you use to manufacture products? Our 203,000 square foot facility is designed and built to standards that exceed food-packaging guidelines. It supports pharmaceutical-grade operations, which greatly enhances our ability to produce the highest quality products quickly. All this means fresher, more effective products on store shelves for consumers. NOW® Foods is an ‘A’ rated GMP-certified manufacturer, one of the first companies in the industry to attain GMP (Good Manufacturing Practices) certification. We’re also certified by QAI (Quality Assurance International) as an organic manufacturer. As consumers become increasingly demanding of supplement quality and safety, NOW® is ready to meet this demand with sound science and state-of-the-art research, manufacturing, and packaging capabilities. We are certain that our efforts to consistently maintain the highest product quality will help make your natural product purchasing decisions easier.
NOW is the leader in quality and value
October 21, 2005 08:12 AM
NOW is the leader in quality and value
“We only deal with companies that support the natural products industry and have a strong public service mission”
We couldn’t agree more. NOW has, and will continue to fight for the rights of consumers to take safe supplements. As one of the most active and influential advocates in the natural products industry, we proudly support the following industry organizations.
NFA, Citizens for health, AHPA, OTA, The Herb Research Foundation, The American Botanical Council, Consumers for Health Choice (UK), The GMO Task Force, The GMP Task Force, American Herbal Pharmacopoeia, The Campaign to label Genetically Engineered Foods, AOAC (method validation), AOCS (American Oil Chemist Society), The Dietary Supplement Education Alliance (DSEA), and More…
“Does NOW support any Charitable or public services?”
NOW is a leading recycling company and was awarded a silver medal for nutrition business journal in 2005 for our dedication to environmental and sustainability issues. We use environmental-friendly packaging and procedures to ensure that our impact on the environment is minimal. Here are just a few of the charities and originations NOW generously supports:
Local Heal Clinics and food banks, Salvation Army, Marklund children’s home, African meal-a-day fund, compassion international, vitamin angel, world relief, Indian orphanage, Hephzibah children’s home, nature conservancy, Americas second harvest, world wild life, and many more
The Immune System - with Kyolic Garlic
July 11, 2005 05:23 PM
The immune system is our body's natural defense system that keeps us healthy. Without it, invading organisms, which we come into contact with constantly, would cause illness and disease. There are many components of the immune system, including natural killer cells, T&B cells, macrophages and many others. Collectively, this network mainly functions against bacteria, viruses, fungi, and parasites.
It is possible for the immune system to be suppressed. Things like stress, unhealthy habits, lack of nutrition, genetics, and other factors damage the immune system, which leaves us vulnerable to disease.
The immune system can benefit from proper, and constant care. A healthy immune system can mean the difference between getting mildly sick versus something much worse. If you are looking for ways to boost your immune system via nutritional supplements, here are a few that might interest you:
Aged Garlic ExtractTM (AGE): Numerous scientific studies have been conducted on AGE in relation to its effect on the immune system. Studies suggest that Aged Garlic Extract may support various immune factors,1-5 such as the ability of immune cells to engulf foreign organisms, T-lymphocyte activity,3 natural killer cell activity1,2 and antibody generation.6 Anti-fungal (Candida albicans-yeast) properties have been shown, and antiviral (herpes1,7, influenza8,9) properties have also been noted. Aged Garlic Extract has also been shown to modify, directly or indirectly, the function of immune cells, which play a leading role in allergic reactions including inflammation.10 In addition, Aged Garlic Extract has been shown to improve age-related deterioration of the immune response.
For your convenience AGE is available as a liquid, and in a capsule, such as the Reserve, FORMULA 100 (tablet or capsule), or as the One Per Day (caplet).
AGE also comes in combination with other herbs and nutrients that may further enhance the immune system. We have formulated a couple of products containing Aged Garlic Extract, specifically for the immune system due to the additional ingredients added that work as an extra boost in this area. Firstly, FORMULA 103 (brown/orange label) in addition to Aged Garlic Extract contains Astragalus, a potent herb demonstrating immune stimulating properties12-17 and vitamin C as Ester-C® (a unique form of Vitamin C) which may support healthy immune function.18 Another product, FORMULA 105 (pink/purple label), contains Vitamins A, C, E, selenium and green tea extract, which are very potent antioxidants. Antioxidants attack free radicals that cause damage to our body, leading to illness and aging. Please keep in mind that the various antioxidant functions attributed to AGE may also help to boost the immune system.
Kyo-Green® is another one of our superb products. Mixing Kyo-Green in a juice or beverage may help to provide extra nutritional support since it is a source of vitamins, minerals, chlorophyll, superoxide dismutase (a very potent anti-oxidant enzyme) and other nutrients. A test tube study by Dr. Lau from Loma Linda University showed that Kyo-Green may provide nutritional support for the immune system by enhancing the activity of macrophages (immune cells that engulf foreign agents).19 Two teaspoons of Kyo-Green also provide the nutrients in a serving of vegetables so this product may function as an easy way to provide extra nutrition for the whole body.
For those who may be interested in a more potent immune boosting formula, please try our Kyo-Green Harvest Blend The Harvest BlendTM contains all of the ingredients in the Kyo-Green, except for the kelp. However, in addition to these ingredients, other active ingredients are added to make forty-four ingredients in total, which may give the immune system a powerful kick. To help support your health there are many different greens, an immune-boosting herbal blend, antioxidant fruits and veggies, immune-enhancing mushrooms, an enzyme active sprout blend, a super energizing blend, special phytonutrients important to immune health, and a nutritious fiber blend. Please read the specifics on each of these constituents, available from the technical information available on this website.
Finally, Kyo-Dophilus® is a probiotic supplement made of a combination of Lactobacillus acidophilus, Bifidobacteria bifidum, and Bifidobacteria longum, which help to maintain a healthy balance of the intestinal microflora and increase our first line of devense in the guy by enhancing macrophages and other immune factors by releasing immune boosting materials. This potent supplement of beneficial bacteria is also ideal for those taking antibiotics, those who are traveling or for those who just want to insure a plethora of beneficial bacteria in their intestinal tracts. Antibiotics are not selective in the bacteria that they kill off. When our friendly bacteria are wiped out, the bad guys have a window of opportunity to take over, as they grow much quicker than our friendly bacteria, and cause us problems. The lactic acid (friendly) bacteria have been shown to produce vitamins, enzymes and antimicrobial compounds that may improve the environment in the intestinal tract. Studies also suggest that friendly bacteria may help to increase resistance to some microbial infections.20-21 Kyo-Dophilus has demonstrated incredible stability at room temperature maintaining more than one billion live cells per capsule through its three-year shelf life. A minimum of one billion live cells per day is considered to be necessary to obtain desired effectiveness from a probiotic supplement. Kyo-Dophilus also comes in tablet form, in a nine-strain formation known as Kyo-Dophilus® 9, and in a smaller form for children, Kid's Kyo-Dophilus®.
Supplying your immune system with adequate nutrition may promote health and ward of illness. If you give the body the tools it needs to heal it-self, it is amazing what it is capable of.
Elder Berry - For Natural Respiratory Health
June 30, 2005 09:30 AM
Elder Berry By Ellen J. Kamhi, Ph. D. with Dorie Greenblatt The plant known as Elder Berry occurs as several different species and grows throughout Europe and North America. It can be a tall tree or smaller bush, earning it the knickname "Dwarf Elder". The berries that appear as the ripe fruits can range in color from red to black. Only the blue/black berries are medicinal. The genus and species name for this variety is Sambucus nigra. This plant has a long history of use as both a food and medicine in many countries. In England, for example, it was a common belief that Elder-Berry was a favorite tree of witches who enjoyed residing among its branches. To disturb such a tree was thought to incur a witch's wrath. To this day, many British still refuse to cut an Elder Tree down or burn its branches. In Denmark, the tree was said to house Hylde-Moer, "The Elder Tree Mother", who would haunt anyone found harming the tree. In addition, many believed that an Elder Tree was a symbol of "good luck" if found growing on one's property.
As a food source Elder Berries are commonly made into jams, jellies, chutneys and wine. As a medicinal, the fruit is often prepared as a syrup. For example, the "Duke of Monmouth's Recipe" was made with Elder syrup and other herbs, and was used for sciatica. Native Americans used different parts of the plant for infections, coughs and skin conditions. Today Elder can be found listed as an "official medicine" in the Holland pharmacopeia, and was listed in the past in the pharmacopeias of both England and the United States.
The most common medicinal uses for Elder Berry are:
Elder Berries contain vitamins A, B and C plus various flavonoids including quercetin. However, these substances alone cannot account for its remarkable effect of disarming the symptoms of a cold or flu. An Israeli scientist, Dr. Madeleine Mumcuouglu, Ph.D., performed research that uncovered the mechanism of activity of Elder Berry's anti-cold and flu activity. The flu is triggered by a virus, which must invade living cells in order to reproduce and spread. The virus enters the cell by puncturing the cell's outer membrane with tiny spikes known as hemagglutinin. Dr. Mumcuoglu discovered that the active ingre- dients in Elder Berry bind onto the hemagglutin, deactivating it and ultimately preventing the piercing of the cellular membranes.
Scientific investigations collaborate the effectiveness of Elder berry. One scientific study tracked a reduction of flu symptoms during an outbreak of influenza. (Zakay-Rones Z, Varsano N, Zlotnik M, et al. Inhibition of several strains of influenza virus in vitro and reduction of symptoms by an elderberry extract (Sambucus nigra L.) during an outbreak of influenza B Panama. J Alt Compl Med 1995; 1:361-9.) An added advantage to the use of Elder Berry is its record of safety. There are no known adverse reactions to the use of Elder Berry, although the possibi-lity of an individual allergic reaction can never be discounted.
Nature's Answer® offers Elder Berry in an alcohol-free, tangy-tasting 4oz. liquid herbal extract form. This concentrated (1:1) maximum strength fluid extract contains 5,000mg of Elder Berry in each 1 teaspoonful dose. Nature’s Answer® also supplies Elderberry in two encapsulated products, Sambucus & Ester-C®, and Sambucus & Maitake Bio-Beta Glucan™.
A great companion product is Nature's Answer®'s Elder Flower (organic alcohol). Flowers from the Elder tree contain tannins that have been shown to help dry up excess mucous, and can act as an expectorant.
One final note...when deciding on an Elder berry liquid, remember to check the kind of sweetener it contains. Many brands add sugar or sorbitol, while Nature's Answer's® Elder berry contains only pure coconut glycerine.
Ester-C® is a licensed trademark of InterCal Corporation and manufactured under U.S. patent #4,822,816 and other patent applications.
Important Information for Allergy Sufferers
May 13, 2005 09:52 AM
Important Information for Allergy SufferersRichard Conant, L.Ac. C.N.
Imagine you are one among millions who greet each spring with worry about the flood of pollen that fills the air this time of year. When the pollen season arrives, as it inevitably does, you find yourself with two choices. You can either take over-the-counter antihistamines and put up with unpleasant side-effects, or endure the sneezing, runny nose, itchy, watery eyes and other discomforts of hay fever.
If there was a natural ingredient, a nutritional substance found throughout nature in many foods and plants, that could offer an alternative, would you not be interested?
Quercetin, one among hundreds of flavonoids found throughout the plant kingdom, is this ingredient. Quercetin has been researched in numerous pharmacological studies. The results of this work strongly suggest that quercetin helps to stabilize the fundamental process in the body which causes an allergic reaction. Quercetin, as shown in test-tube ("in vitro") studies, prevents the release of histamine from "mast cells," immune cells that stand guard in the tissues which meet the outside environment—the nasal passages, the lungs, the digestive tract and skin. While this has yet to be confirmed by human clinical trials, in the picture that emerges from the research so far, quercetin looks like a rescue nutrient for allergy sufferers.
Reports from Quercetin Users
I have seen numerous reports from individuals who have indeed achieved significant reductions in allergic sensitivity by using quercetin. And this includes food allergies as well as environmental allergies. Anecdotal stories like these carry little weight among scientists, because they do not provide evidence that the observed result will be repeated in other cases. Only placebo-controlled, double-blind studies can produce this kind of scientific proof. Yet, when anectodal evidence (this includes physician "case reports") correlates with the results of pharmacological research such as we have on quercetin, I believe it should be taken seriously. And quercetin is a nutrient that works effectively when taken as a dietary supplement.
For example, one gentleman writes that his wife, who is allergic to pollen and dust, is now "sneeze-free" after using quercetin for three years. A Pennsylvania woman writes that her husband, also a long time allergy sufferer, "seems to be nearly allergy free" after one month of use. Another man says that "quercetin has literally changed my life." These are not isolated cases; a respected nutritionist who specializes in allergies and environmental problems has seen many similar outcomes with a quercetin. Clearly something significant is going on with respect to quercetin as a nutritional approach for overcoming allergies.
Bear in mind, though, that quercetin does not function like an antihistamine medication; it is not a quick fix. As a nutrient that helps to normalize body functions naturally, quercetin needs time to work, and should be taken for at least two or three weeks to achieve these results.
Exerting a broad range of biological effects, quercetin is perhaps the most active and versatile flavonoid. In test-tube studies, quercetin acts directly on the mast cell in a way that quiets the allergic response.
An allergic reaction occurs when IgE antibodies, positioned on the mast cell surface, come in contact with a potential allergy-causing substance like pollen. The mast cell is then signaled to release histamine from storage granules located inside the cell, through a process called "degranulation." The histamine circulates throughout the body, causing the runny nose, itching and other discomforts associated with allergies.
Quercetin stabilizes mast cell membranes, in effect turning down the allergic response signal. Quercetin also slows other mechanisms which are involved with inflammation, such as the production of inflammatory prostaglandins and leukotrienes. This adds to its membrane-stabilizing effect, and its value in allergy control.
Quercetin appears to substantially raise the threshold for initiation of an allergic reaction. In allergy sufferers this threshold is low, for reasons which are not well understood. They may have more IgE antibodies than normal, making the mast cells overly "trigger happy." Histamine has its proper place in the immune response that defends us against truly harmful foreign substances in the body. But like many chemicals produced by the body, histamine is a two-edged sword. In allergy-prone individuals, the mast cells have become overreactive, releasing too much histamine, unnecessarily. With quercetin in the bloodstream, histamine release from mast cells is kept under control. Quercetin's ability to down-regulate both the inflammatory and allergic responses makes it, I believe, a highly important nutrient for humans to consume on a regular basis.
Quercetin-the Scientific Evidence
Several studies, published in respected journals such as the Journal of Allergy and Clinical Immunology and others, have demonstrated quercetin's ability to control the release of histamine from mast cells. (Quercetin has the same effect on basophils, a type of white blood cell that also contains histamine.) In these experiments, mast cells taken from both animals and humans are exposed in the test tube to various substances—called "antigens"— that stimulate histamine release. The researchers then add an inhibiting agent such as quercetin to the mixture and measure the differences in histamine output. Quercetin has shown itself to be one of the more powerful histamine inhibitors, more powerful, in fact, than disodium cromoglycate, an anti-asthma drug.
Quercetin has other beneficial properties. A strong antioxidant, Quercetin has a higher level of antioxidant activity than both vitamin C and vitamin E. (Quercetin enhances the antioxidant activity of vitamin C; quercetin and vitamin C are true synergists.) Quercetin has been shown to block the oxidation of LDL cholesterol by free radicals. Quercetin also protects cell membranes from being injured by oxidized LDL. The damage that oxidized LDL causes to the delicate membranes of blood vessel linings allows plaque deposits to form, setting the stage for atheroslcerosis. These observations point to quercetin as a key nutrient for maintaining cardiovascular health.
Like all flavonoids, quercetin is not classified as an essential nutrient, although flavonoids were once called "Vitamin P." In view of its many beneficial actions, quercetin is a nutrient that clearly has important roles to play in human nutrition, for allergy sufferers, and for everyone.
May 12, 2005 01:08 PM