Search Term: " Polypeptide "
Why Should I Take Wheat Grass Liquid Concentrate?
December 10, 2014 11:03 PM
What is a wheat grass
Wheat grass benefits
Wheat grass concentrate
This liquid concentrate is packed with nutrients equivalent to five pounds of raw, green organic vegetables, all in just two ounces of juice. It is higher in vitamins A and C than what you would get in a serving of carrots or oranges, and has a full spectrum of B vitamins as well, and a balanced ratio of calcium, magnesium, sodium, potassium and phosphorus altogether. Wheat grass contains enzymes that detoxify the body, especially the blood and liver, neutralizing harmful pollutants like heavy metals and toxins that enter the body, which could be stored in tissues and organs, therefore cleansing the body from head to toe. This juice is also a resource of life-force energy that gives one renewed spiritual effects on his inner being. It battles premature aging and it keeps the hair from graying out making you look younger. Not only does it boosts the immune system by giving strength, vitality and endurance, but has wonderful effects on the body. It can cure acne and may help remove scars left if drank regularly for a few months. It acts, as a natural deodorizer hence can be a body deodorant. It can prevent tooth decay and even soothe toothaches and sore throat. It aids in skin problems like psoriasis or eczema. It helps in achieving regular bowel movement. It is gluten-free. Taking wheat grass liquid concentrate has no reported side effects or toxic in any amount given to either humans or animals, mainly because it is at its finest and most natural form, making it the ideal supplement to take nowadays.
January 18, 2014 06:37 AM
What is Amino Peptide
A amino peptide is basically a little protein which is made up of amino acids. Peptides are animated at quite little dosages, are greatly particular and have a quite great wellbeing profile when utilized physiologically - that is, to support or change a living being's physical methods. When we dismember a percentage of the peptide marks above, we can start to separate around them. The utilization of "amino" in amino-Polypeptide is a spot excess since all peptides are made of amino acids. The "poly" just implies this is a peptide of a few amino acids. A "hexapeptide" is a chain of precisely six (hexa) amino acids; a pentatpeptide is a chain of five (penta). One scientist working with a palmitoylated five-amino-harsh corrosive chain peptide named it "palmitoyl pentapeptide", while an alternate scientist examining the same atomcalled it "palmitoyloligopeptide". This is a honest to goodness, however less particular, name since "oligo" implies "few". Along these lines the disarray develops.
The expression "neuropeptide" is a smidge more accommodating in that it really portrays the capacity of the peptide. Neuropeptides about as neuromodulators, neurotransmitters, neurohormones, and hormones. Research into neuropeptides has blasted in later a long time to the degree that there is an investigative diary named
Neuropeptides whose point is the quick distribution of unique research and survey articles, managing the structure, circulation, activities and capacities of peptides in the focal and fringe anxious frameworks. What is energizing about neuropeptides is their energy and scope. Different neurotransmitters transmit focal anxious framework motions in one bearing and along a way from A to B.
Neuropeptides transmit omnidirectionally outward and can even immediate transmissions in converse. As neuromodulators, they can initiate and deactivate different neurotransmitters. The deductive personality boggles at the potential. The names of a percentage of the neuropeptides may be natural and help you to comprehend the potential of opening the privileged insights of these peptide particles. Neuropeptides are aggregated into families dependent upon similitudes in their amino harsh corrosive successions. There are the Tachykinins; the Insulins; the Somatostatins; the Gastrins, for example, cholecystokinin used to diagnose gallbladder and pancreatic issues; and the Opioids, for example, enkephalins - the figure's sedatives or painkillers.
How Does Methylsulfonylmethane (MSM) Improve Joint Health?
October 06, 2011 01:18 PM
As we all know, our health is truly fragile thus, there is a very big need for all of us to take good care of our health by engaging in different ways and means to strengthen it. However, because of the kind of world that we live in right know, there are times when it is very difficult to live healthy because of all the temptations that are detrimental to our health. Fortunately, due to the constant innovations and advancement in the field of medicine, various supplements are already identified that are proven to be effectual in helping you maintain optimum health. One of these great supplements that are available today is methylsulfonylmethane.
Methylsulfonylmethane or more commonly known for its abbreviation MSM is a very vital and effectual supplement. Several studies have been conducted and would prove that MSM cures wide array of medical conditions such as gastrointestinal disorders, joint problems, and allergic reactions. The supplement is also used to improve circulation, cell vitality, as well as enhance skin elasticity and smoothness. MSM also have active components that could lessen post athletic activity fatigue.
MSM performs two very significant processes in the human body. A portion of the excess MSM that you consumed will be flushed out from your body in about 12 hours. And along with the excretion of MSM are the detrimental toxins that are injurious to your health. It is also part in the cellular makeup of the cell walls of all the new cells that is manufactured by your body because as we all know, our body is constantly producing new cells to replace cells that are already old. During the process of cell creation MSM plays a vital role to make the production successful. MSM is incorporated in the Polypeptide bonds that make up the cell walls. As a result, cell walls become more permeable therefore, nutrients and vitamins can easily pass through. Without the presence of MSM, cells would become impermeable thus the person would experience nutrient deficiency.
Aside from improving overall health, MSM is also proven to be effectual in maintaining joint mobility. Various clinical studies would also validate and prove that pain and inflammation brought about by arthritis, gout, and other medical conditions that involve the joints showed significant improvement after taking MSM supplement. The reason behind its efficacy is because of the sulfur enhancement of the sodium-potassium pump which in turn enhances fluid flow and removal of cell toxins therefore could cure inflammation and pain.
Because of all these good things for your health that you could get from MSM, it is really a supplement that you need to take. And if you are one of the many who are suffering with joint pains and inflammation for quite some time now, then it would be suitable enough to give MSM a try and allow yourself to embrace the wonderful changes in your body and health.
Grab some MSM for yourself and feel the difference it can make in your life!
Can Dietary Collagen Help the Skin and Joint Tissue?
June 30, 2011 10:45 AM
Collagen and Your Health
Collagen is the most common form of protein in humans and other mammals. It is a major constituent of the extracellular matrix that provides structural support to animal cells from the outside. It displays great tensile properties, which is responsible for the strength and elasticity of the skin. Since it is a component of fibrous tissue, it is also found in ligaments and cartilages that make up joint tissue.
Dietary collagen has long been postulated to contribute to the biochemical composition of cells present in the skin and joints. Proponents of collagen supplements believe that dietary collagen is assimilated into the extracellular matrix and fibrous tissue. The scientific community has been doubtful about the efficacy of topical applications of collagen, but oral supplements have been promising in clinical trials.
Molecular collagen is composed of polymers of amino acids linked by peptide bands, which are too big at the cellular level to get absorbed through skin. On the other hand, intestinal absorption of dietary collagen remains a matter of controversy. That being said, nutraceutical companies have developed formulations of supplements that facilitate the best possible absorption rates and better bioavailability.
Tough bundles of collagen fibers comprise several Polypeptide chains of fibrous structural proteins. All fibrous tissues have cells and extracellular matrix in between. High concentrations of collagen found in cartilages, ligaments, tendons, fascia, and even bones give these fibrous tissues tensile strength, the reason why the joints are capable of bearing a certain level of longitudinal stress without tearing apart.
Structural proteins make up the outer layer of the human skin and its appendages, such as the scalp, hair, and nails. The most important of these proteins are collagen, keratin, and elastin. Collagen fibers are responsible for the tensile properties of the skin. Keratin provides strength whereas elastin exerts an elastic effect. Collagen fibers affect the process of healing and its degradation leads to wrinkles.
Oral route of administration is believed to produce the health benefits linked to dietary collagen. While researchers have ruled out the health claims tied to collagen creams and lotions, they have reported encouraging results about dietary collagen. In fact, collagen supplements utilized in the management of rheumatoid arthritis and treatment of skin disorders have produced significantly positive outcomes.
One clinical trial that involved more than 200 participants diagnosed with rheumatoid arthritis point to the medicinal potential of collagen as an adjunct treatment for rheumatism and osteoarthritis. There was a noticeable decrease in joint pain, morning stiffness, and restrained mobility, which were noted as statistically significant. For this reason, supplementation of collagen has attracted more research.
Dietary collagen is now becoming increasingly visible in the nutraceutical industry in that sales have increased in the past few years. It has become the subject of numerous studies well underway, and as such developments in collagen supplementation are expected to produce formulations specialized for higher bioavailability. The good news is dietary collagen has not been linked to any adverse effects.
Get some collagen today and feel the difference it can make in your diet!
Supplements good for reducing stress and boosting energy!
March 26, 2007 02:05 PM
More and more Americans are feeling overworked, overtired, and overcome by life’s demands. We just do not have the energy we need to meet our responsibilities to the people we care about. More importantly, we don’t even have the energy to have fun! It seems that a constant feeling of fatigue has become part of the American way of life.
Research has shown that the same processes that cause lack of energy can rob us of sleep, saddle us with excess weight, disrupt our hormonal balance, and create significant amounts of stress in our daily lives. Chronic stress can dramatically contribute to fatigue, sleep disorders, irritability, and anxiety. The research simply confirms what most of us already know – uncomfortable stress can really wear us out mentally and physically! It can take away the satisfaction of a job well done. It can take away our ability to believe in ourselves. And, sadly and maybe most importantly, continual stress can take the fun and joy out of life.
In a separate issue of Ask the Doctor, we discuss the energy and sleeping needs of people suffering from chronic fatigue syndrome and fibromyalgia. In this issue, I discuss the 3-step process I call “Vitality 101.” People do not have to accept pain, insomnia, or fatigue. It’s time for everyone to feel great and have a life they love!
Step 1 – Nutrition
Good overall nutrition is important for everyone! As a foundation product to support energy levels, a powdered drink mix is a pleasant, easy way to ensure that you are taking all of the necessary vitamins, minerals, and amino acids that you need to have great energy all through your day.
The following chart lists the most critical ingredients. You can see that almost all of the vitamins and minerals work together to help improve energy levels and overall health.
In addition to the powdered energy drink mix, it is important that you also take a high potency vitamin B-complex supplement. This should include niacinamide, thiamin, riboflavin, vitamin B6, vitamin B12, pantothenic acid, and choline, which are especially important to restore the energy production needs of your body. It is also critical to get enough water, as most Americans are chronically dehydrated.
Step 2 – Rest Your Body
Having trouble sleeping is one of the most troubling symptoms of stress. While the stress is wearing us down and making us tired, it’s also keeping us tense and unable tot relax. The result? That easy drift into sleep becomes harder and harder. And if we are lucky enough to actually get some shut-eye, stress will often wake us up, sometimes several times a night.
This occurs because excess stress suppresses the sleep center in the brain. It is important to break the “stress/insomnia cycle” early, before it results in pain and hormonal and immune dysfunction!
Because good quality sleep is how the body repairs and re-energizes itself, it may be helpful to use herbal products to promote good quality sleep. There are many natural supplements that are marketed as sleep formulas. To get the best results, it is very important that the right ingredients are in the sleep formula you buy. Look for a supplement that has a blend of herbs that promote deep sleep, such as valerian, L-theanine, hops, passionflower,
Step 3 – Manage Excess Stress Levels
In this fast paced world, it is important to learn to manage the stressor in our lives. Glandular extracts, such as raw adrenal extract, can offer natural support to help our bodies deal with the effects of stress and, in turn, can boost your energy levels. Exercise is another stress buster. Using your body physically is important for good health. Find something that is fun for you, however, or you are unlikely to stick with it!
Q. Does stress zap my energy in any other ways besides making me lay awake at night and causing me to be a zombie the next morning?
A. Most people are familiar with the body’s dramatic response to an emergency. The heart pounds, the muscles constrict, and the lungs expand – and while this is happening, we are capable of greater than normal strength and speed. This response is the body’s way of rescuing itself when faced with an emergency. We don’t have to think about it to make it happen. It’s automatic.
The same can be said of a chronic stress response. Whether we’re late for a business meeting because we’re stuck in traffic, or worrying about how we are going to pay for our children’s college tuition, our response to stress happens automatically. The difference between the two is that the body’s response in an emergency starts and resolves itself quickly. The response to being stuck in traffic may not.
The body makes the “stress hormone”, cortisol, to handle the normal stresses of day-to-day living. But in an emergency situation, the adrenal glands, located above the kidneys, secrete increased amounts of this hormone until the emergency passes. Then the body returns to its normal function. Unfortunately, however, chronic stress is more complex. When our body is subjected to increased amounts of the hormone, cortisol, for an extended time, it can lead to a condition known as “adrenal burnout” or “adrenal fatigue.” While it’s true that very large amounts of cortisol can have damaging effects on our hormones, too little cortisol doesn’t allow us to respond to stress properly. It’s really a matter of balance.
Q. How can I control the stress in my life and re-energize?
A. Many people who are under constant stress may have adrenal burnout. Adrenal burnout occurs when the adrenal glands are constantly producing cortisol in response to chronic stress. Over time, this exhausts the adrenal reserve, meaning the adrenal gland can no longer increase cortisol production in response to stress.
The good news is that changes in our hormone levels can return to normal when stress is decreased. The key in learning how to deal with daily stress is to allow the body to return to its normal state. I discuss additional techniques for coping with stress in my recent book Three Steps to Happiness! Healing Through Joy (see my website, www. jacobeitelbaum .com, for more information). In addition to stress control, it is important to supplement your adrenals with a glandular therapy regimen to ensure healthy cortisol levels and adrenal function. Glandular therapy, which uses the concentrated forms of bovine (cow) or porcine (pig) glands, can improve the health of our glands. Pioneers in the field of endocrinology (the study of hormones) hypothesized that glandular extracts work by providing nutrients the body lacked and thus repaired the malfunctioning gland.
If you are one of the unlucky folks with stressed-out adrenal glands, you should see great results from taking raw adrenal supplements. Be sure to buy adrenal extract supplement that contains both whole adrenal and cortex adrenal.
The best adrenal supplement should also contain vitamin C, vitamin B6, pantothenic acid and licorice. Licorice contains glycyrrhizin, which is broken down into glycyrrhizic or glycyrrhetinic acid. This compound inhibits the activity of an enzyme that turns active cortisol into inactive cortisol. While in high amounts (greater than 100 mg of glycyrrhizic acid/day), licorice administration causes hypertension, no such effects have been observed at lower doses. Experts have speculated that inhibition of the cortisol-converting enzyme may reduce cortisol-related symptoms associated with adrenal insufficiency. The adrenal glands use these nutrients to manufacture cortisone and other compounds. It just makes sense to purchase an adrenal supplement with these supportive ingredients.
Did your grandmother ever tell you to eat your liver so that you didn’t get “tired blood?” Well, it turns out that she was right. Liver extract is another glandular extract that can help improve energy levels.
Liver extract is an excellent source of highly bioavailable nutrients including iron, B vitamins (especially B12), and other minerals. The stamina and energy-enhancing benefits of liver are widely touted. Liver extract has been shown to support healthy function of the liver and increase the energy levels inside our body.
Because heat will destroy the key components in the liver, a high quality liver extract supplement should be cold-processed and encapsulated to enhance speed and absorption of nutrients from liver. A high quality aqueous liver extract supplement should also contain vitamin B12 to support healthy blood iron and oxygen levels to energize.
Q. It will be great to get a good night’s sleep. Are there also any other natural alternatives that could help promote relaxation and increase my energy levels during the day?
A. Yes, there are. Rhodiola rosea is an all-natural herb that has long been used to help relieve stress and increase energy. Rhodiola has also been used to lift our moods, improve sexual satisfaction, and even help in certain nervous system disorders. First used in Siberia and
In clinical trials, the most effective Rhodiola rosea extract was found to contain 3% rosavins and 1% salidroside. While there are many Rhodiola supplements in health food stores, only those containing these specific amounts can provide the best results.
Altered digestion, food intolerances, decreased energy, fatigue, cognitive problems, and sleeplessness create the need for changes in daily living routines. These can include alterations in diet; exercise modifications; alterations in activities of daily living according to one’s energy level; and sleep/rest management. All may require the assistance of a professional clinician, such as a chiropractor, nutrition specialist, physical and/or occupational therapist, mental health professional, or sleep therapist.
Super busy lives demand super strength nutrition. Begin each day with a powdered nutritional supplement after getting at least 8 hours of sleep each night. In addition to the nutritional beverage mix, a vitamin B complex supplement should be taken every morning. The nutritional drink mix and the vitamin B complex supplement will ensure that your body has all the vitamins, minerals, amino acids, and other nutrients to combat your fatigue. Taking a daily adrenal supplement, like the one discussed earlier, will provide the much needed (and often depleted) nutrients your body may be lacking, and help you recover lost energy. Rhodiola rosea, and ginseng can offer additional natural nutritional support in your busy life to boost your energy levels. These nutritional supplements can be used daily and you will feel energized to get through each day’s challenges and opportunities!
March 08, 2007 12:27 PM
Revita, the most efficient hair growth stimulating shampoo available in the market is the final result of DS Laboratories efforts on cutting edge research. Revita is a powerful and unique SLS/SLES free combination of active ingredients specially designed to maintain scalp vitality and act on folicle dysfunctions in order to achieve best results in short periods of time. Sodium Lauryl Sulfate and Sodium Laureth Sulfate, commonly used low cost detergents in shampoos and cleansers, are linked to skin irritation, skin drying and hair loss due to follicle attack. Revita is Sodium Lauryl Sulfate and Sodium Laureth Sulfate free, providing a high quality scalp skin safe shampoo product.
Revita was developed with a cost-no-object approach. Revita’s compounds have been chosen based exclusively on their properties, quality and efficacy (in the opposite of the majority of available products, which are usually developed with production costs in mind). The final result is a very high quality shampoo product with absolutely no equivalent competitor in the market. Revita combines costly first line compounds at high concentrations like Caffeine at 4.0%, Pyrus Malus (Apple) Seed Extract at 1.0% and Spin Traps (SOD Mimic) at 0.1% with other top level ingredients which make Revita a unique product in its class.
To improve the efficacy of this synergic combination, DS Laboratories developed a unique “chemical free” extraction process that keeps original properties and clinical efficacy of final components. Through gentle mechanical compression, Revita’s compounds are obtained as pure and chemically preserved active molecules.
Revita starts acting on your scalp and hair follicle since the first day of use. The time you will need to note the first results will depend of the severity and duration of your hair loss. No matter how long or how intense your hair loss is, using Revita on daily basis will improve the vitality of your scalp, maintaining the quality of your hair and stimulating new hair growth.
Through the synergic interaction of very effective compounds, Revita brings you a highly effective product designed to maintain scalp vitality and act on hair loss. By combining an antioxidant effect, anti-DHT properties, powerful hydrating molecules, hair growth stimulants and structural amino acids, Revita brings you the most effective hair growth stimulating shampoo available.
Apple Polyphenol (procyanidin B2 and C1) - phytochemical concentrate found in the skin of unripe apples that acts as potent antioxidant. It protects cells against free radicals, reactive atoms that contribute to tissue damage in the body. These chemical compounds are being studied extensively in labs around the world for their health effects in major diseases including treatment of hair growth. Studies showed that after sequential use, an increase of almost 80% of hair diameter and an increase in number of total hairs was shown, with no side effects.
In 2000, Japanese researchers presented their findings to the international community on the hair growth effects of apple polyphenols - specifically one known as procyanidin B-2. They identified two successful compounds- one from chardonnay grapes, and one extracted from unripe apples. The procyanidin B-2 fraction clearly outperformed the grape extract. "Procyanidin B-2 purified from apples," stated the research team, "shows the highest activity of more than 300% relative to controls."
In the same year, in a double-blind placebo-controlled trial, nineteen men with male pattern baldness were studied with a daily topical application of a 1% procyanidin B-2 solution, extracted from apples. Ten other balding men served as controls, receiving a placebo solution. After 6 months, the study concluded:
• The increase in number of total hairs and terminal hairs in the procyanidin B-2 group subjects was significantly greater than controls.
• 78.9% of subjects showed an increased mean value of hair diameter.
• "Procyanidin B-2 therapy shows promise as a cure for male pattern baldness."
Following the revelations, an attempt was made to further understand the mechanism by which the remarkable hair growth effects occurred. The results were published in the prestigious British Journal of Dermatology: Procyanidin B-2, extracted from apples, promotes hair growth: a laboratory study, Br J Dermatol. 2002 Jan;146(1):41-51. In this study, the researchers concluded that procyanidin B-2 acts to diminish protein kinase C isozymes, which play an important role in the hair growth cycle. Procyanidin B-2 seems to promote hair growth by down regulating PKC in both the anagen (active growth phase) and telogen (resting phase) of the hair follicle. When the anagen phase is prolonged, and the telogen phase is shortened, increased hair growth results.
Two more clinical trials and a total of seven published studies have now confirmed the surprising hair growth-promoting effects of apple procyanidins. Here is a summary of those findings:
• Total Number of Hairs: Significantly Increased
• Total Number of Terminal Hairs: Significantly Greater
• Increase in Hair Diameter: 78.9% Positive • Ratio of Thicker (terminal) Hairs: Significantly Higher
• Hair Follicle Activation: Intensive
In the most exciting development yet, Japanese researchers released a new study late in 2005. Once again, procyanidin therapy was proven successful in regrowing hair in subjects with male pattern baldness. The new study, published in the Journal of Cosmetic Dermatology, confirmed the findings of earlier studies, showing clear improvement in the number of hairs and the density of hairs in the treated area. Building on the success of earlier trials, the study was extended to 12 months in the procyanidin group, and proved that longer term procyanidin therapy was even more successful than prior 4 and 6 month trials.
Cooper Peptides - Cooper Peptides have two main properties: (1) potent tissue protective anti-inflammatory agents that limit oxidative damage after tissue injury, and (2) tissue remodeling activation agents, that is, the processes for removal of damaged protein and scar tissue and their replacement by normal tissue. Studies at numerous universities and research institutes have found copper-peptides to improve hair transplant success, increase hair follicle size, stimulate hair growth and reduce hair loss.
Research scientists at the University of San Francisco Wound Center stumbled upon very interesting results. Their discovery was made while applying a synthetically formulated compound, Copper Peptide, to severe wound areas on several patients. During this process something unusual happened. Not only did the wounds heal about 30 percent faster, but a significant stimulation of the follicular cells occurred. As a side effect, these tripeptide complexes actually grew hair around the wound area.
The discovery was so startling that they then applied the same Copper Peptide complex to a female patient who had suffered roughly 90 percent alopecia (hair loss) for years. After about six months of use, she had recovered almost 100 percent of her hair. Dr. Loren Pickart, the leading authority in Copper Peptide technology, describes it as being like a protein injection to the scalp.
Tests were then conducted with chemotherapy patients and recent hair transplant recipients, all with great success in stimulating newer and stronger hair follicles.
Spin traps – are very special compounds that were originally utilized in measuring free radical activity because they react with free radicals both in vitro and in vivo, producing stable complexes. The most commonly used spin trap and the standard which measures new ones is PBN - alpha-phenyl- N-tert butyl nitrone. Hundreds of studies have been conducted over the last ten years that have tested PBN and other “spin traps” in numerous conditions. Later it was discovered that these spin traps had powerful free radical quenching abilities in living systems and could treat a variety of conditions. Spin traps could provide unique protection against free radical damage that complements and enhances the activities of the classical antioxidants such as vitamin C and vitamin E.
Spin traps modulate NF kappa-B regulated cytokines and inducible nitric oxide synthases that are implicated in pro-inflammatory disease conditions. A method for ameliorating a cellular dysfunction of a tissue such as the treatment of hair loss and stimulation of hair growth comprises administering a nitroso or nitrone spin trap to the affected tissue. These agents inhibit the reaction of superoxide and nitric oxide to produce peroxinitrite. Scientists discovered that nitrone and nitroso spin traps have properties in the body for ameliorating cellular dysfunction in tissue attributed, in part, to high energy oxygen and hydroxyl free radicals, and enhancing recuperation of the tissue. Alpha-phenyl-N-tert butyl nitrone (PBN) can be administered, for example, as an anti-alopecia agent to stimulate hair growth.
Spin traps can be administered to the skin to be treated, such as the scalp. Depending on the type of hair loss or alopecia being treated and the conditions thereof, the stimulation of hair growth can usually be obtained by topical application, preferably repeated daily application. The utility of topically applied spin traps is not limited thereto, however, and the stimulation of hair growth can include an increased rate of growth, increased hair diameter, follicular neogenesis, and the like; inhibiting hair loss or alopecia from progressing.
Ketoconazole - Topical ketoconazole shows itself to have an anti-DHT binding effect in the scalp. Nevertheless, it is likely that ketoconazole exhibits other methods to its anti-hair-loss effect. One such theory of ketoconazole anti-alopecia effects may be on its activity upon the removal of sebum, a fatty substance that accumulates in the scalp around the hair follicles. In addition, ketoconazole is an antifungal medication and is significant for people combating hair loss since acting as an antifungal agent it reduces scalp irritation caused by fungal colonization or infection. Reduction of the inflammatory process that occurs in male pattern alopecia is crucial.
If we first examine the role of androgens, specifically dihydrotestosterone (DHT), we find that this hormone has been thought to slowly "choke" the growth of the hair follicle by inhibiting the function of an enzyme in the hair follicle called adenylate cyclase. Suffice it to say that when DHT concentrations remain high in the scalp, we see terminal (thick, coarse) scalp hair become reduced to vellus hair (fine, thin peach fuzz). On March 04, 2001, at the American Academy of Dermatology Meeting in Washington DC, scientists presented the findings of a study done on 1% ketoconazole shampoo which had good news for hair loss sufferers. In the study presented, one hundred male volunteers with mild to moderate dandruff and somewhat oily scalp, were using in a double-blind fashion either a 1% ketoconazole shampoo or a 1% zinc pyrithione shampoo, 2-3 times a week for 6 months.
Analysis of the different parameters set up in the study shows that the hair diameter gradually increased with ketoconazole use (+8.46%) over a 6 month period, whereas the diameter showed a trend to decrease with zinc pyrithione use over the same period (-2.28%). The sebum excretion rate was reduced with ketoconazole (-6.54%) while it increased with zinc pyrithione (+8.2%) over the same period of time. The number of hairs shed over a 24-hour period was reduced by 16.46% with ketoconazole and 6.02% with zinc pyrithione after 6 months. Finally, the percentage of hairs in the anagen phase increased by 6.4% and 8.4% respectively during the study.
The results are similar to a previous study done on 2% prescription strength Ketokonazole where it was shown that use of 2% ketoconazol yielded an increase in hair shaft diameter similar to what was achieved by the control group using 2% Minoxidil and a non-medicated shampoo.
Rooibos - Rooibos or Red Bush Tea - a hardy shrub indigenous to the North Western Cape of South Africa – is an exciting new botanical ingredient with potent antioxidant and anti-inflammatory properties well documented in medical literature. In alternative medicine Rooibos is often prescribed for nervous tension, allergies, stomach and digestive problems. Results from an independent study also showed a significant improvement in hair loss. Studies were initiated at an independent laboratory (Dermascan, France) to study the effect of the use of Rooibos in a hair lotion on a group of healthy persons who were suffering from the problem of hair loss. A 90 day trial was conducted comparing a hair lotion containing Rooibos with a placebo lotion.
After 90 days results showed a significant increase of the hair growth in the lotion containing Rooibos compared with the placebo. An increase in the hair growth was observed with 89% of the volunteers with no undesirable reactions (irritation or allergy). The participants were next asked to fill in a questionnaire. When the results were tallied, 67 percent rated their hair loss as zero or low, 78 percent saw a low to medium improvement, 45 percent saw a low to medium regrowth of hair, and 63 percent considered their hair had become smoother and shinier.
Conclusion: results show that most of the volunteers had a remarkable improvement in both the increase of hair growth and the decrease in hair loss.
MSM - Sulphur is present in protein-rich foods containing high levels of the amino acids methionine and cysteine. These foods include meat, fish, legumes, nuts, eggs, and vegetables, especially onions. However, sulphur has recently become a popular nutritional supplement and topical treatment thanks to the discovery of methylsulfonylmethane, or MSM.
The use of MSM as a nutritional supplement and topical application is relatively recent. An American chemist named Robert Herschler, began studying MSM in 1955. However, another man, Dr. Stanley Jacob with Oregon Health Sciences University in Portland, is considered by many to be the father of MSM. Dr. Jacob found that simple marine life like algae and plankton convert inorganic sulphur to organic sulphur compounds. These compounds are known as dimethylsulfonium salts. These salts are transformed into dimethyl sulfide (DMS), which is released into the atmosphere and is converted by ultraviolet light into dimethyl sulfoxide (DMSO). When DMSO oxidizes, it turns into MSM and is absorbed by plants that become food for animals and humans. MSM is a white, crystalline powder that is odorless and nearly tasteless. When taken as a dietary supplement, MSM proved to have the same health benefits as DMSO without side-effects such as bad breath, itchy skin, nasal congestion, and shortness of breath. Why does MSM help with the development of stronger hair? Various scientific studies have proven that MSM contributes a definite normalizing effect on body functions. The sulfur normally provided to the body by MSM is required for healthy collagen and keratin which are essential for healthy hair, skin and nails. MSM also has proven antioxidant benefits which can disrupt or alter damaging chain reactions of lipid peroxidation in the cell membranes.
MSM has been widely used as a dietary supplement without any reports of allergy or intolerance related to its use. Supplements of MSM are comfortably assimilated without side effects. There are no known contraindications.
Caffeine 4% - Active caffeine ingredient helps to regulate the effects of testosterone levels. Male pattern baldness is known to occur in individuals with sensitivity to testosterone, causing damage to hair follicles that eventually leads to baldness. Caffeine is a xanthine alkaloid compound that acts as a stimulant in humans. Caffeine is a central nervous system (CNS) stimulant, having the effect of warding off drowsiness and restoring alertness.
The independent study at the University of Jena used hair samples from the scalps of young men entering into the first stages of hormone-related hair loss. The study relied on a hair organ culture that used four different types of testing samples. The first was a nutrient-based sample, the second a testosterone only sample, the third was a caffeine only sample and the fourth a mixture of caffeine and testosterone.
According to the research, the results showed that the samples containing the caffeine nutrient helped to stave off hair loss and encouraged new hair growth, while the sample that relied on testosterone only led to increased hair loss. But perhaps the most impressive was the testosterone and caffeine sample, which helped to prevent further hair loss.
The results showed that using the caffeine treatment average growth was increased by around 46 per cent and the life cycle of the hair was extended by 37 per cent, when compared to the control study.
Carnitine Tartrate - L-Carnitine, a vitamin-like nutrient, occurs naturally in the human body and is essential for turning fat into energy. Active energy metabolism is an essential prerequisite for the growth of strong and healthy hair. In biological systems ATP acts as the universal energy currency. One of the most potent bio-actives that significantly increases cellular ATP content is carnitine tartrate.
Statistical evaluation demonstrated a significant increase in ATP equivalents in human hair roots treated with carnitine tartrate, showing that carnitine tartrate is an ideal ingredient for hair care formulations, providing energy for the optimal environment to produce strong and healthy hair. Throughout the test period ATP content within plucked hair follicles was determined twice daily using a commercially available test kit. Statistical evaluation of baseline adjusted values demonstrated a significant increase in ATP equivalents in human hair roots treated with carnitine tartrate. These effects were absent in the placebo group, thus underlining the stimulating activity of carnitine tartrate.
The outstanding bio-activity of carnitine tartrate was furthermore demonstrated in a second study, assessing the effects after a single application of a shampoo formulation supplemented with carnitine tartrate. Again, ATP levels in plucked human hair follicles were significantly increased.
Amino Acids: Ornitine, Taurine, Cysteine - Amino acids are the building blocks of protein, from which hair is created. They are assembled in the correct sequence by stem cells to form keratin, a complex and immensely strong hair protein. Vital amino acids have to be replaced consistently, as damage is accumulated over time. We can replace a combination of these lost amino acids directly into the hair, where they are shown to provide significant tensile benefits to the hair shaft.
Hair is composed primarily of proteins (88%). These proteins are of a hard fibrous type known as keratin. Keratin protein is comprised of what we call "Polypeptide chains.” The word, Polypeptide, comes from the Greek word "poly" meaning many and "peptos" meaning digested or broken down. In essence, if we break down protein, we have individual amino acids.
Many (poly) amino acids joined together form a "Polypeptide chain". Two amino acids are joined together by a "peptide bond", and the correct number of amino acids placed in their correct order will form a specific protein; i.e. keratin, insulin, collagen and so on. The "alpha helix" is the descriptive term given to the Polypeptide chain that forms the keratin protein found in human hair. Its structure is a coiled coil. The amino acids link together to form the coil and there are approximately 3.6 amino acids per turn of the helix (coil). Each amino acid is connected together by a "peptide bond". The peptide bond is located between the carbon atom of one amino acid extending to bond with the nitrogen atom of the next amino acid. In many individuals the extremities, including the top of the head, are the most difficult places to maintain blood flow. Follicles which are constantly deprived of blood, and therefore nutrients, cannot produce hair properly. Lack of proper nutrients, amino acids, minerals and vitamins can certainly hamper hair growth.
L-Arginine is a semi-essential amino acid synthesized by the body from L-Ornithine. Arginine + Ornithine support protein synthesis because they are involved in the transport and storage of nitrogen. The usage of taurine corrects the "rigidification" of the connective sheath that surrounds the Pilosebaceous unit and hair follicles, specifically those affected by pattern hair loss. This is a novel and previously undisclosed angle on hair loss treatment that has yet to be touched upon in any of the medical literature or prior publications.
The amino acid, l-cysteine speeds up hair growth and increases hair shaft diameter resulting in fuller hair. L-cysteine has been reported to facilitate longer hair growth, beyond what is genetically programmed. L-cysteine also provides potent antioxidant protection to the hair follicle. Users of topical n-acetyl-cysteine have reported hair regrowth.
Emu Oil - The emu, dromaius nova hollandiae, is a flightless bird part of a group called ratites which also includes the ostrich and the kiwi. Modern Australians learned early on from the Aborigines the many valuable qualities in the emu and its oil. The earliest research studies in emu oil come from Australia, and Australia continues to export emu oil to this day.
In the United States today there is a growing network of research labs interested in emus and their incredible oil. Emu oil is rendered from a thick pad of fat on the back of the bird that was apparently provided by nature to protect the animal from the extreme temperatures in its Australian homeland. Emu oil is deep penetrating and super hydrating to the skin - an all-natural tissue nutrient. Michael Hollick, MD, Ph.D., Professor of Medicine, Physiology, and Dermatology at Boston University School of Medicine conducted a study involving emu oil and hair growth. His study found that there was a 20% increase in growth activity of skin that received emu oil compared to skin that received corn oil. Looking at the hair follicles Dr. Hollick realized they were much more robust, the skin thickness was remarkably increased suggesting that emu oil stimulated skin growth and hair growth. Additionally, the study showed that over 80% of hair follicles that had been "asleep" were woken up, and began growing.
Emu oil is anti-inflammatory, which may be in part why it stimulates hair growth. Emu Oil has also been shown to be a 5 alpha reductase inhibitor in target tissues when topically applied, which likely contributes significantly to its hair growth properties. A third important property of emu oil is that it is bacteriostatic.
Emu Oil contains a multitude of Essential Fatty Acids (EFA) which helps to "feed" the skin. Consumers who suffer from natural forms of baldness have reported hair re-growth. Since Alopecia Areata only suppresses the hair follicle (vs. killing the hair follicle), emu oil may have an effect to assist with hair regrowth.
Biotin – Biotin is a member of the B-vitamin family and a major component in the natural hair manufacturing process -- it is essential to not only grow new hair, but it also plays a major role in the overall health of skin and nails. The beneficial effects of biotin on hair may be linked to its ability to improve the metabolism of scalp oils. Biotin when absorbed by the scalp may promote hair growth and it is able to penetrate the hair shaft making it expand which actually thickens the hair cuticle.
Biotin is used in cell growth, the production of fatty acids, metabolism of fats and amino acids. It plays a role in the Krebs Cycle, which is the process in which energy is released from food. Biotin is so important to hair health, that many dermatologists prescribe biotin supplements to their patients as part of their medical treatment for hair loss.
After applying Revita with a gentle massage, you should leave it on the scalp from 1 – 2 minutes before rinsing. Then repeat and leave on the scalp for 3 – 5 minutes. If desired, follow with a high quality conditioner. For optimal results, Revita should be used at least 5 times per week.
This formulation is contraindicated in individuals with a history of sensitivity reactions to any of its components. It should be discontinued if hypersensitivity to any of its ingredients is noted.
Q. Is Revita safe ?
A. Revita primarily contains compounds that are not only safe in topical use, but actually dramatically enhance overall skin health. The other active ingredients such as Ketoconazole have been tested in clinical studies and have been shown safe.
Q: Can I use hair sprays, mousses, gels, etc.?
A: Hair spray, gel, and other styling aids are not recommended since they tend to clog the hair shaft. However, you can use them while using Revita.
Q: Can I have my hair colored or permed while using Revita ?
A: While there is no evidence that coloring or perming hair can lead to or even worsen hair loss, it is generally not recommended for people with hair loss. If you are experiencing hair loss then perming and coloring hair is not recommended. However, this will not interfere with Revita.
Q: What is SLS/SLES free ?
A: SLS means Sodium Lauryl Sulfate and SLES means Sodium Laureth Sulfate, commonly used low cost detergents in shampoos and cleansers. They are linked to skin irritation, skin drying and hair loss due to follicle attack. Revita is Sodium Lauryl Sulfate and Sodium Laureth Sulfate free, and that means that Revita does not irritate you scalp and preserves your hair follicale health.
Q: Can I blow dry my hair after using Revita ?
A: Extreme heat damages the proteins in the hairs making them fragile. Nevertheless, if you need or want to blow dry your hair, you can do it after using Revita.
Q: Who is a candidate for Revita ?
A: Ideal candidate is someone with little hair loss or at the beginning stages of hair loss, since it is much easier to prevent hair loss then to grow new hair. Someone who is concerned with hair loss prevention should start using Revita immediately.
Q: What type of results should I expect with Revita ?
A: When deciding to use Revita, it is important to have realistic expectations. Depending of severity and duration of your hair loss, it could take some time to see hair growth. In fact, during the first 2 weeks of treatment you may actually notice increased hair loss as old hairs are being pushed out and the hair follicles start growing new hair. Do not become alarmed with this and just stick to the treatment.
Q. Does Revita have any systemic side effects ?
A. No, when used as directed, Revita active ingredients have a long history of use both orally and topically.
Q. Does Revita work for women?
A. Yes. In most cases, the cause of hair loss in women is surprisingly similar to men. Fortunately for women, estrogen helps to protect the hair follicle from the destructive effects of DHT. However, many women develop thinning hair and loss due to fluctuation of estrogen levels and/or over production of DHT. Revita can help protect the hair follicle from DHT resulting in a thicker, fuller and healthier hair.
Q. I am using other topical treatments. Can I use Revita at the same time ?
A. Yes. Revita has no side effects and does not cross react with other topical treatments. You can safely opt to use Revita with other products, and we strongly recommend the association with Spectral.DNC for more severe hair loss or Spectral.RS for thinning hair.
Q. Do I need to use Revita for a long time ?
A. Once you have reached the desired results, you should continue to use Revita as your regular shampoo to maintain the revitalized hairs and a healthy scalp.
Q: Is stress a factor in hair loss?
A: When the body is under significant physical and emotional stress it is possible that the immune system will produce anti-bodies that attack hair follicles, and this results in bald patches or diffuse loss. Stress-induced loss will respond very well to Revita and you should keep using Revita as your regular daily shampoo to keep your scalp healthy.
Digestive enzymes and Herbs
August 25, 2006 02:26 PM
Digestive enzymes and Herbs
Raw food naturally contains the proper types and proportion of enzymes to assist in its own digestion. Food enzymes are released by the action of chewing, which ruptures the foods cell membranes. Like salivary enzymes, raw food enzymes play an important role in human digestion by predigesting food in the upper stomach, where contents may site for as long as an hour before gastric secretions deign their action.
Since enzymes are essentially destroyed at 118 degrees F, most forms of cooking and industrial food preparation render food devoid of enzyme activity. This places the full burden of digestion on the body processes and reserves. In time, this burden can weaken or overwhelm an individual’s ability to process and absorb vital food nutrients. Many health professionals believe that the prevalence of cooked and processed foods in modern society makes supplementation with digestive enzymes essential. Digestive enzymes also may be a benefit to those who suffer from clinical disorders of digestion and absorption.
Consider these advantages
Perplexed about Protein? immunoglobulins to boost the immune system.
April 29, 2006 01:58 PM
The Wellness Revolution
Perplexed about Protein?
As protein and whey powders have advanced in popularity, the confusion about them has grown. In particular, protein processing technology has advanced by leaps and bounds; consumers are being presented with protein claims and counter-claims that are highly contradictory.
The confusion is part of a rapid growth. Little Miss Muffet’s quiet dish of curds and whey has expanded from a minor sideline aid for weight lifters, with sales increases around to percent a year, into an explosive $1 billion a year industry, with some companies announcing sales growth of 110 percent in just the last year.
The increase in market is from whey’s expanding appeal. As new technology has made whey’s nutritive value beneficial to a wide range of consumers, more people are using whey, and whey is being added to more products. The problem is, those advanced nutritive qualities are not included in all whey products. The fantastic immune benefits, for example, apply to only the top tier of whey products.
The standard of protein quality—the ability to provide indispensable amino acids—is judged on the basis of digestibility, nutrients, and amino acid composition. Whey has historically been acknowledged as on of the best sources of high quality protein.
With the increasing popularity of whey, attention on new processing methods has raised the bar on quality, and new products have greatly expanded nutritional values. What may have been an acceptable high-quality whey protein a few years ago, no longer makes the grade. Tony Lucchesi, Natural Sales Trainer at Source Naturals says, “The different processing methods have changed the entire protein market.”
He explains, “In separating casein from whey, (a process used to make cheese), most processing methods use heat, chemical modification, or pH adjustments. These all damage the native protein structure. The result is little or no biological activity in the whey product. All the low temperature drying and micro-filtration won’t help if the raw material is denatured before a protein is dried and brought to market.”
Damaged protein may have been acceptable a few years ago, but it isn’t now. Lucchesi continues, “Animal experiments have shown that Polypeptides—whole, non-denatured proteins—have greater nutritional value than protein isolates.”
Protein isolates are what is left after the pasteurization process. The protein has traditionally been “Cross cooked” out of its normal balance. “What you have left are incomplete bits and pieces of whole protein,” he says. These protein bits have only partial nutrients.
The latest introduction to the protein category are concentrates, which are intact, biologically-active whole proteins. The entire difference is in the processing; high heat, acids, and traditional methods of separating the caseins from the whey are no longer used. The new processing preserves the nutrients of the protein. This is the method that is the basis for a new Source Naturals whey product, True Whey.
Lucchesi says, “TRUE WHEY is different in that it was designed to provide nutritional support for enhanced immune function. The entire process was designed for nutritive value. The preservation of these nutrients—lactoferrin, glutamine, immunoglobulins—give TRUE WHEY a huge benefit to athletes, children, and anyone interested in boosting their immune system.”
Per serving, TRUE WHEY offers 8 grams of un-denatured protein that includes 900 mg immunoglobulins and 190mg of lactoferrin. Its vanilla flavoring has gotten very high reviews, and it has a two-year shelf life. It appears that the bar has truly been raised in the whey protein category!
AMINO ACIDS AND PROTEIN
June 09, 2005 09:48 AM
AMINO ACIDS AND PROTEIN
Next to water, protein is the most abundant substance in the human body. Complex mega-molecules of protein are the structural building blocks of tissue. The thousands of different proteins in our bodies are composed of 20 molecules called amino acids. In the last 20 years, research has shown the benefits of amino acid supplementation to such diverse areas of human biochemistry as metabolism, enzyme and neurotransmitter production and antioxidant protection. Source Naturals utilizes the latest-breaking research to bring you a highly comprehensive line of amino acid supplements.
DNA provides the instruction manual for life, RNA reads the manual and the genetic information is expressed by proteins. Proteins are the most abundant macromolecules in living cells constituting 50% or more of their dry weight. They create the structure of our cells and tissues, and play an essential role in virtually all of the biochemical events that animate those tissues.
The term "protein" refers to a set of macromolecules that encompasses an extensive variety of structure and function&endash;from helical rods with the tensile strength of steel to elastic sheets to huge molecular machines with hinged jaws that snap closed to hold other molecules in place. Amazingly, all proteins, in their remarkable variety, are built out of a set of 20 simple molecules called amino acids.
Amino acids are one of the four types of small molecules out of which all life is constructed. The other three are: palmitic acid (see "Essential Fatty Acids," page #), adenine and glucose. All amino acids share a common chemical "backbone" which consists of an a -carbon atom to which four substituent groups are bonded: a nitrogen-containing amino group (H2N), a carboxyl group (COOH), a hydrogen atom and an "R" group. The "R" group or side chain (figure #) varies in electric charge, size, structure and solubility in water, giving each amino acid its distinct chemical properties. Since all amino acids (except glycine) contain at least one asymmetrical carbon atom, each one exists in at least two forms: the l form and its mirror image or stereoisomer, the d form. While both forms are found in biological systems, only the l form is present in proteins.
Amino acids are linked together like beads on a string to form proteins, sometimes called peptides because of the peptide bonds that link the amino acids together. They range in size from simple two-amino-acid dipeptides to Polypeptides which contain more than 1800 connected amino acids. The chemical backbone of the amino acids and their sequence constitutes the primary structure of a protein. Polypeptide chains then fold into specific 2 and 3-dimensional configurations that are unique for each type of protein. The pattern of folds, along with the chemical nature of the amino acid side chains contained in it, give a protein its characteristic biological activity. For example, the connective tissue proteins collagen and elastin give structure to cellular organelles and tissues, while proteins called enzymes catalyze and facilitate metabolic chemical reactions.
Nine of the 20 amino acids involved in protein synthesis are considered "essential";they cannot be synthesized by the body and must be obtained from food sources. The term "non-essential" is sometimes used to classify the other eleven amino acids. However, this word is perhaps a misnomer; a better term might be synthesizable. These amino acids are just as vital to human metabolism as the "essential" amino acids; so vital that the body can synthesize them. They are, however, more available, more versatile, and more interchangeable.
When the presence or absence of a particular amino acid will determine whether a protein can be created or not, that amino acid is called a rate-limiting factor for that protein. For example, the tripeptide glutathione, a compound that forms an important part of the body's protective mechanisms, is made of the amino acids glutamic acid, glycine and cysteine. Glutamic acid and glycine tend to be plentiful in the diet, and can be easily interconverted. Cysteine is the rate-limiting factor for glutathione; the amount of cysteine in the diet will determine the amount of glutathione that can be manufactured by the body.
Amino acids have a special role to play in brain nutrition, because all neurotransmitters are derived from amino acids or related compounds such as choline. Brain neurotransmitters, specifically, are biochemical keys to the workings of the mind. They are substances that perform chemical transmission of nerve impulses between neurons or between neurons and other cell types such as muscle. They work in the following way: an electric current (or action potential) travels down the length of a neuron, or nerve cell, until it reaches the synapse - a narrow gap between two cells. The incoming nerve impulse triggers the release of neurotransmitter (NT) molecules, which diffuse across the synaptic gap. The neurotransmitter molecules bind with receptor proteins embedded in the membrane of the post synaptic neuron and activate a physiological response. Excitatory neurotransmitters propagate a new action potential while inhibitory NT's inhibit the development of new action potentials.
The amino acid precursors of neurotransmitters are able to cross the blood-brain barrier, a structural feature of brain anatomy that prevents many substances from contacting brain tissue. Thus, it is possible to influence brain metabolism (and therefore emotional states) through the mechanism of neurotransmitter synthesis. The enhancement of neurotransmitter production is one of the most exciting advancements to occur in the field of nutrition in modern times.
A major portion of the amino acid requirement in humans is derived from the proteins in food. Successive proteolytic enzymes attack the peptide bonds, cleaving one amino acid at a time from the Polypeptide chain. Ultimately, free amino acids as well as small peptides (especially dipeptides) are absorbed through the mucosal cells of the small intestine. The small peptides are then further hydrolyzed so that only free amino acids enter the liver and portal vein. This sounds like a fairly straightforward process. However, the presence of a particular amino acid profile in a certain food does not guarantee the assimilation of those amino acids when the food is ingested. There are three types of amino acids: acidic, basic and neutral; each of these classes has a different transport mediator. Therefore, there is competition for the carrier between any two amino acids in a certain class, both in the digestive tract and at the blood-brain barrier. Thus, the isolation of "free-form" amino acids is an important aid to nutritional engineering. In many cases, the consumption of high potencies of a particular amino acid allows that nutrient to overwhelm the competition for absorption. The resulting increase in blood and tissue levels will yield the benefits conferred by that nutrient.
The isolation of free-form amino acids is an important advancement in the field of nutrition science. Amino acid supplements offer a broad range of choices to complement your nutritional program.