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The powerful neuroprotective properties of curcumin revealed in science study: Stunning 30 percent improvement in memory Darrell Miller 7/1/18
Our Liver Breaks Down Hormones Darrell Miller 9/14/16
Difference Between D-2 And D-3 and benefits of Vitamin D Darrell Miller 1/13/14
Antioxidants For The Body Darrell Miller 6/10/08
Supplements good for reducing stress and boosting energy! Darrell Miller 3/26/07
Chronic Fatigue Syndrome and Fibromyalgia Darrell Miller 2/28/07
Benefits of Camu Camu Powder Extract Darrell Miller 8/29/06
Hayfever & Allergies - Herbs To Help You Breathe Easier Darrell Miller 6/30/05
Improove Memory ... Darrell Miller 6/9/05
Pycnogenol Complex - The Next Generation of Antioxidant Protection Darrell Miller 6/4/05
Neptune Krill Oil (NKO) - for Healthy Heart, Joints, and other Body systems Darrell Miller 6/3/05
Heart Science - A Five-Tiered Approach to Heart Health ... Darrell Miller 6/2/05
GlucosaMend™ Tissue/Joint Repair Complex Darrell Miller 6/2/05
COENZYME Q10 - Transforming food into energy Darrell Miller 6/1/05
Cholestrex - Lower Cholesterol with Source Naturals Supplements Darrell Miller 6/1/05
Bioflavonoid Complex - Botanical Antioxidant Protection Darrell Miller 6/1/05




The powerful neuroprotective properties of curcumin revealed in science study: Stunning 30 percent improvement in memory
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Date: July 01, 2018 09:54 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: The powerful neuroprotective properties of curcumin revealed in science study: Stunning 30 percent improvement in memory





The powerful neuroprotective properties of curcumin revealed in science study: Stunning 30 percent improvement in memory

The component found in turmeric that gives the spice its brightly colored appearance is also directly responsible for helping enhance and preserve our neurological development. When given in doses of 90 mg each day, turmeric was shown to help improve memory in those who were suffering from some level of memory loss. The cognitive improvement is due to turmeric being high in curcumin, which makes it a natural aid in alleviating many cognitive deficiencies that happen due to age.

Key Takeaways:

  • Often overshadowed by it's anti-inflammatory characteristics, Turmeric is also a potent neuroprotector.
  • Research has shown that the main ingredient, curcumin, can improve memory.
  • A recent study found that participants given curcumin daily had a 30% improvement in their memory tests and PET scans showed improved signaling in the brain.

"The participants were randomly assigned to a placebo group or a control that took 90 milligrams a day of curcumin twice a day over the course of year and a half. Researchers measured everyone’s curcumin levels in their blood at the trial’s inception and conclusion."

Read more: https://www.naturalnews.com/2018-06-28-the-powerful-neuroprotective-properties-of-curcumin-improved-memory.html

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Our Liver Breaks Down Hormones
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Date: September 14, 2016 02:38 PM
Author: Darrell Miller
Subject: Our Liver Breaks Down Hormones

The liver is the second largest and most important organ in the human body. Its main function in the body is detoxification of toxic wastes in the blood stream. The endocrine glands are responsible in the production of hormones , which are key to normal functioning of the liver. The liver breaks down hormones like insulin, adrenalin, testosterone and estrogen on a 24/7 basis.  If the liver did not break down hormones, these hormones would run unchecked, for example, insulin, if left in the blood would cause sugar levels to drop to dangerously low levels. The liver helps prevent that and other hormones from causing damage to the body.

The liver general plays a major regulatory role in breaking down the excess hormones after they have completed their intended functions in the body.

It is important to keep the liver functioning properly, this means do not drink in excess,  limit over the counter drugs and prescription drugs, continued use can cause liver damage.  Cholesterol medications can hammer the liver, try to clean up diet and take natural remedies to lower cholesterol and protect the liver.  Consider taking milk thistle as a liver Protector.  For years, scientist have been studying milk thistle, and it is proven to be a safe and effective herbal remedy that protects the liver.



//www.ncbi.nlm.nih.gov/pubmed/334126

//www.innerbody.com/image_digeov/card10-new2.html

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Difference Between D-2 And D-3 and benefits of Vitamin D
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Date: January 13, 2014 04:19 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Difference Between D-2 And D-3 and benefits of Vitamin D

Vitamin D

Vitamin D is one of the most essential vitamins for body and best thing about this Vitamin is that your body can easily make with the help of sunlight and food, but you need to get out in the sunlight for that. Talking about the health benefit of this vitamin it can help your body to absorb the calcium from food and it can help you to get stronger bone. It also helps the cell to cell communication that allows your body to have a better immunity system. In addition to this can also help you in several other problems including reduced heart attack risk, protection from arthritis and lot more.

Types of Vitamin D

Talking more about it, five different type of Vitamin D are available there out of them vitamin D2 and Vitamin D3 are the most essential D vitamins for body. Out of these two vitamins Vitamin D2 is also known as ergocalciferol because only invertebrate animals, fungus and animals can make it with the help of sunlight. Many scientists also believe that Vitamin D2 can act as a sun Protector as well for many organisms and it can protect them from harmful UV rays of sunlight.

At the same time Vitamin D3 is the vitamin that your body can make by itself using sunlight and your food substances. However, it is very important that your body need to get exposure of sunlight and exposure of UV should be higher than UV 3 for synthesizing of Vitamin D.

Since, now a day’s it is very difficult to stay in sunlight due to work requirement and when people go out, they prefer to use some UV protection that can reduce the chances for Vitamin D synthesizing. Therefore, it is suggested that you should take it as a dietary supplement and you should consume it on a daily basis you can get a healthy and strong bone structure along with a fully functional cellular system so you can have a great immunity system as well

 

References:

  1. //ods.od.nih.gov
  2. //www.medicalnewstoday.com

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Antioxidants For The Body
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Date: June 10, 2008 11:27 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Antioxidants For The Body

Eating the fruits and vegetables that naturally contain antioxidants is the best way to get them into your system. Mixing them into a well-balanced and healthy diet is the best method of all. This way you reap the benefits of all of the antioxidants in a natural combination.

The benefit of dietary antioxidants is that they slow the chemical process of oxidation. This oxidation is what causes narrowing of the arteries and heart-related health problems due to cholesterol deposits. Eating a regular variety of herbs, vegetables and fruits that contain antioxidants is the best way to maintain good health. Some foods that contain antioxidants include:

* Tomatoes
* Garlic
* Onions
* Rosemary
* Grapes
* Pomegranates

Antioxidant supplements are available, lab testing have shown that they are just as effective as their natural counterparts. Natural foods contain ranges of antioxidants that work together synergistically. These combinations of antioxidants are much more effective.

More Benefits:

Antioxidants and other nutrients are needed by the body to protect against cell damage. They also may reduce the risks of certain forms of cancer.

It has been discovered that the mitochondria (cell power plants) are a major source of oxidant production. They are also a target for the damaging effects of the very oxidants that they produce. This is a major cause in the advancement of cellular aging, called apoptosis.

It is believed that in apoptosis, each cell has a fixed number of cell divisions that it is capable of. After the cell has used its allotted number of divisions, it ceases to function. Oxidative damage is also a contributing factor of DNA mutation, which causes further malfunction of the cells.

Most Common Antioxidants:

The following is a list of the most common antioxidants, what benefits they offer and where to find them:

*Beta-carotene keeps the skin healthy and promotes growth and development of bones. It also helps to prevent night blindness and fight infection. Beta-carotene is found in vegetables and fruits: carrots, cantaloupe, apricots, broccoli, peppers, tomatoes, spinach, sweet potatoes and pumpkin.

* Vitamin C destroys free radicals inside and outside cells. It helps in the healing of wounds, preventing bruising, formation of connective tissue, iron absorption and keeping gums healthy. Vitamin C is being studied for its beneficial effects in reducing cataracts, cancer and heart disease. Foods high in vitamin C include tomatoes, citrus fruits and juices, berries, mango, papaya, peppers, cabbage, spinach, broccoli and potatoes.

* Vitamin E acts as the essential fat Protector in cell membranes and red blood cells. It reduces the risk of heart disease, cancer and other diseases associated with age. Vitamin E is found in peanut butter, nuts, seeds, vegetable oils, margarine, whole grains, wheat germ, salad dressings and avocado.

* Selenium helps the body maintain healthy hair and nails. It also enhances immunity and, along with Vitamin E, prevents cell damage. Vitamin E reduces the risk of cancers, especially prostate, lung and colorectal. The best sources of Selenium include brazil nuts, garlic, meat, eggs, poultry, seeds, seafood and whole grains. The amount of selenium found in plants depends on the soil content in which they are grown.

Antioxidants benefit the body by providing a layer of protection for the tissues and cells. They are the front line of the body's protection against free radicals. Free radicals are unstable by-products of oxygen that cause premature aging and degenerative diseases. They also come from environmental sources, such as pollution, UV rays and other toxins. Foods rich in antioxidants help to clean free radicals from the body. They also help to prevent various age-related diseases, cancers and heart disease.

Maintaining a healthy, nutritionally balanced body that has the ability to fight disease and infection is a prime way to live a long, disease free and happy life. Regular ingestion of antioxidant rich foods or supplements is the best method to achieve this.

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Supplements good for reducing stress and boosting energy!
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Date: March 26, 2007 02:05 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Supplements good for reducing stress and boosting energy!

Vitality 101

 

More and more Americans are feeling overworked, overtired, and overcome by life’s demands. We just do not have the energy we need to meet our responsibilities to the people we care about. More importantly, we don’t even have the energy to have fun! It seems that a constant feeling of fatigue has become part of the American way of life.

Research has shown that the same processes that cause lack of energy can rob us of sleep, saddle us with excess weight, disrupt our hormonal balance, and create significant amounts of stress in our daily lives. Chronic stress can dramatically contribute to fatigue, sleep disorders, irritability, and anxiety. The research simply confirms what most of us already know – uncomfortable stress can really wear us out mentally and physically! It can take away the satisfaction of a job well done. It can take away our ability to believe in ourselves. And, sadly and maybe most importantly, continual stress can take the fun and joy out of life.

In a separate issue of Ask the Doctor, we discuss the energy and sleeping needs of people suffering from chronic fatigue syndrome and fibromyalgia. In this issue, I discuss the 3-step process I call “Vitality 101.” People do not have to accept pain, insomnia, or fatigue. It’s time for everyone to feel great and have a life they love!

 

Step 1 – Nutrition

Good overall nutrition is important for everyone! As a foundation product to support energy levels, a powdered drink mix is a pleasant, easy way to ensure that you are taking all of the necessary vitamins, minerals, and amino acids that you need to have great energy all through your day.

The following chart lists the most critical ingredients. You can see that almost all of the vitamins and minerals work together to help improve energy levels and overall health.

Nutrients

Effect on Vitality & Energy

Vitamin A

Essential for healthy skin and mucous membrane integrity, healthy immune system responses and healthy bone growth and healthy reproductive processes. Vitamin A in the form of beta-carotene is an antioxidant and free radical fighter.

Vitamin C

Necessary for the proper functioning of the immune system. Antioxidant, free radical fighter. Assists with hormone synthesis; supports healthy skin integrity; supports healthy iron absorption.

Vitamin D

Essential for healthy calcium and phosphorus metabolism, and the absorption of vitamin A; supports bone mineralization.

Vitamin E

Helps oxygen circulation; supports healthy nerve transmissions; supports healthy leg nerves and muscles; helps boost energy levels.

Magnesium

Supports enzyme activity involved in energy production; supports healthy nerve and muscle function; supports healthy immune system functions

Malic Acid

Catalyst to stimulate the complete burning of fuel for energy; supports healthy connective tissue and muscle functioning.

Betaine

Works with B vitamins to synthesize amino acids, and acts as a precursor to SAM-e. SAM-e (S-adenosylmethionine) is a naturally-occurring molecule in the body, and may have an effect on overall mood elevation

Selenium

Works with vitamin E to maintain healthy cell membranes; supports healthy thyroid functioning.

Zinc

Supports healthy immune system, healthy enzyme processes and healthy immune response.

Amino Acids

Glycine, Serine, Taurine, Tyrosine are essential for the production of energy in the body. Also essential for brain function.

Fructooligosaccharides

Provides nutrition for good bacteria in the intestinal tract, improving digestion and healthy microflora.

In addition to the powdered energy drink mix, it is important that you also take a high potency vitamin B-complex supplement. This should include niacinamide, thiamin, riboflavin, vitamin B6, vitamin B12, pantothenic acid, and choline, which are especially important to restore the energy production needs of your body. It is also critical to get enough water, as most Americans are chronically dehydrated.

 

B Vitamins

Effect on Vitality & Energy

Thiamine B1

Supports healthy energy, growth, appetite, and learning capacity; healthy red blood cell production; carbohydrate metabolism and the production of hydrochloric acid.

Riboflavin B2

Riboflavin (vitamin B2) is crucial in the production of body energy. Supports healthy glutathione reductase activity, which helps maintain glutathione, a major Protector against free radical damage. Vitamin B2 itself also has antioxidant qualities.

Niacinamide B3

Niacinamide is an essential nutrient for the healthy metabolism of carbohydrates, fats, and proteins, as well as for the production of hydrochloric acid for digestion.

Pantothenic Acid B5

An essential component in the production of coenzyme A, a vital catalyst that is required for the conversion of carbohydrates, fats, and protein into energy.

Pyridoxine HCL B6

Aids in the conversion of amino acids to carbohydrate or fat for storage or energy. Also required for the production of serotonin, melatonin, and dopamine. Since it aids in the formation of several neurotransmitters it is an essential nutrient in the regulation of mental processes.

Vitamin B12

An essential nutrient for healthy energy production. Vitamin B12 helps support metabolism of carbohydrates and fats. It contributes to healthy cell formation and cellular longevity.

Folic Acid

Folic acid promotes energy production and supports the immune and nervous systems. Folic acid works best when combined with vitamin B12. Recent research shows folic acid can reduce the amount of the amino acid homocysteine in the blood.

 

Step 2 – Rest Your Body

Having trouble sleeping is one of the most troubling symptoms of stress. While the stress is wearing us down and making us tired, it’s also keeping us tense and unable tot relax. The result? That easy drift into sleep becomes harder and harder. And if we are lucky enough to actually get some shut-eye, stress will often wake us up, sometimes several times a night.

This occurs because excess stress suppresses the sleep center in the brain. It is important to break the “stress/insomnia cycle” early, before it results in pain and hormonal and immune dysfunction!

Because good quality sleep is how the body repairs and re-energizes itself, it may be helpful to use herbal products to promote good quality sleep. There are many natural supplements that are marketed as sleep formulas. To get the best results, it is very important that the right ingredients are in the sleep formula you buy. Look for a supplement that has a blend of herbs that promote deep sleep, such as valerian, L-theanine, hops, passionflower, Jamaica dogwood and wild lettuce. This combination of herbs is important as each herb addresses a different aspect of sleeplessness and muscle tension caused by stress. Taking only one or two of these herbs alone is much less likely to be effective.

 

Ingredients

Effect on Sleep

Wild Lettuce

Has been found to have sedative effects.

Hops

Acts as a mild sedative and has a sleep inducing effect.

Jamaica Dogwood

Has been found to be mildly sedative and is often used for anxiousness.

L-Theanine

Causes significant increases of neurotransmitter concentrations in the brain, which promotes muscle relaxation and improves sleep.

Valerian

This herb has been clinically studied for its ability to improve sleep quality.

Passionflower

This herb eases nervousness and insomnia.

 

Step 3 – Manage Excess Stress Levels

In this fast paced world, it is important to learn to manage the stressor in our lives. Glandular extracts, such as raw adrenal extract, can offer natural support to help our bodies deal with the effects of stress and, in turn, can boost your energy levels. Exercise is another stress buster. Using your body physically is important for good health. Find something that is fun for you, however, or you are unlikely to stick with it!

 

Q. Does stress zap my energy in any other ways besides making me lay awake at night and causing me to be a zombie the next morning?

A. Most people are familiar with the body’s dramatic response to an emergency. The heart pounds, the muscles constrict, and the lungs expand – and while this is happening, we are capable of greater than normal strength and speed. This response is the body’s way of rescuing itself when faced with an emergency. We don’t have to think about it to make it happen. It’s automatic.

The same can be said of a chronic stress response. Whether we’re late for a business meeting because we’re stuck in traffic, or worrying about how we are going to pay for our children’s college tuition, our response to stress happens automatically. The difference between the two is that the body’s response in an emergency starts and resolves itself quickly. The response to being stuck in traffic may not.

The body makes the “stress hormone”, cortisol, to handle the normal stresses of day-to-day living. But in an emergency situation, the adrenal glands, located above the kidneys, secrete increased amounts of this hormone until the emergency passes. Then the body returns to its normal function. Unfortunately, however, chronic stress is more complex. When our body is subjected to increased amounts of the hormone, cortisol, for an extended time, it can lead to a condition known as “adrenal burnout” or “adrenal fatigue.” While it’s true that very large amounts of cortisol can have damaging effects on our hormones, too little cortisol doesn’t allow us to respond to stress properly. It’s really a matter of balance.

 

Q. How can I control the stress in my life and re-energize?

A. Many people who are under constant stress may have adrenal burnout. Adrenal burnout occurs when the adrenal glands are constantly producing cortisol in response to chronic stress. Over time, this exhausts the adrenal reserve, meaning the adrenal gland can no longer increase cortisol production in response to stress.

The good news is that changes in our hormone levels can return to normal when stress is decreased. The key in learning how to deal with daily stress is to allow the body to return to its normal state. I discuss additional techniques for coping with stress in my recent book Three Steps to Happiness! Healing Through Joy (see my website, www. jacobeitelbaum .com, for more information). In addition to stress control, it is important to supplement your adrenals with a glandular therapy regimen to ensure healthy cortisol levels and adrenal function. Glandular therapy, which uses the concentrated forms of bovine (cow) or porcine (pig) glands, can improve the health of our glands. Pioneers in the field of endocrinology (the study of hormones) hypothesized that glandular extracts work by providing nutrients the body lacked and thus repaired the malfunctioning gland.

 

Adrenal Extract

If you are one of the unlucky folks with stressed-out adrenal glands, you should see great results from taking raw adrenal supplements. Be sure to buy adrenal extract supplement that contains both whole adrenal and cortex adrenal.

 

The best adrenal supplement should also contain vitamin C, vitamin B6, pantothenic acid and licorice. Licorice contains glycyrrhizin, which is broken down into glycyrrhizic or glycyrrhetinic acid. This compound inhibits the activity of an enzyme that turns active cortisol into inactive cortisol. While in high amounts (greater than 100 mg of glycyrrhizic acid/day), licorice administration causes hypertension, no such effects have been observed at lower doses. Experts have speculated that inhibition of the cortisol-converting enzyme may reduce cortisol-related symptoms associated with adrenal insufficiency. The adrenal glands use these nutrients to manufacture cortisone and other compounds. It just makes sense to purchase an adrenal supplement with these supportive ingredients.

 

Ingredients

Effect on Stress

Adrenal Polypeptide Fractions & Adrenal Cortex Extract

Polypeptide fractions are easily digested and help support the thyroid and the adrenal gland to regulate levels of cortisol and other hormones.

Vitamin C

Provides extra support during periods of chronic stress.

Vitamin B6

Required to make serotonin, melatonin and dopamine – all vital for maintaining energy levels – very important in dealing with stress-filled lifestyles.

L-Tyrosine

L-tyrosine is an amino acid that supports nerve transmission and healthy adrenal, thyroid and pituitary glands. Converts to epinephrine and norepinephrine, brain neurotransmitters crucial during times of stress.

Licorice

The component of licorice called glycyrrhizin, which breaks down into glycyrrhizic acid. This compound inhibits the breakdown of cortisol produced by the body, helping balance this important hormone. Glycyrrhizic acid’s mechanism of action is through the inhibition of 11-beta-hydroxysteroid dehydrogenase. This enzyme catalyzes the conversion of cortisol to cortisone. It also inhibits the metabolism of corticol, and minimizes the binding of cortisol to mineral corticoid receptors.

 

Liver Extract

Did your grandmother ever tell you to eat your liver so that you didn’t get “tired blood?” Well, it turns out that she was right. Liver extract is another glandular extract that can help improve energy levels.

Liver extract is an excellent source of highly bioavailable nutrients including iron, B vitamins (especially B12), and other minerals. The stamina and energy-enhancing benefits of liver are widely touted. Liver extract has been shown to support healthy function of the liver and increase the energy levels inside our body.

Because heat will destroy the key components in the liver, a high quality liver extract supplement should be cold-processed and encapsulated to enhance speed and absorption of nutrients from liver. A high quality aqueous liver extract supplement should also contain vitamin B12 to support healthy blood iron and oxygen levels to energize.

Ingredients

Effect on Stress

Liver Fractions

Liver extract may have anti-vital properties and increase the mitochondrial production of adenosine triphosphate (ATP). ATP is an important carrier of energy in the cells.

Vitamin B12

B12 is necessary for the production of red blood cells and healthy blood oxygen levels.

 

Q. It will be great to get a good night’s sleep. Are there also any other natural alternatives that could help promote relaxation and increase my energy levels during the day?

A. Yes, there are. Rhodiola rosea is an all-natural herb that has long been used to help relieve stress and increase energy. Rhodiola has also been used to lift our moods, improve sexual satisfaction, and even help in certain nervous system disorders. First used in Siberia and Russia, Rhodiola is now being extensively studied and has been found to increase resistance to toxins (both physical and chemical), balance the work of the body, help memory storage and mental functioning, and improve resistance to physical and emotional stress.

In clinical trials, the most effective Rhodiola rosea extract was found to contain 3% rosavins and 1% salidroside. While there are many Rhodiola supplements in health food stores, only those containing these specific amounts can provide the best results.

 

Lifestyle Treatments

Altered digestion, food intolerances, decreased energy, fatigue, cognitive problems, and sleeplessness create the need for changes in daily living routines. These can include alterations in diet; exercise modifications; alterations in activities of daily living according to one’s energy level; and sleep/rest management. All may require the assistance of a professional clinician, such as a chiropractor, nutrition specialist, physical and/or occupational therapist, mental health professional, or sleep therapist.

 

Conclusion

Super busy lives demand super strength nutrition. Begin each day with a powdered nutritional supplement after getting at least 8 hours of sleep each night. In addition to the nutritional beverage mix, a vitamin B complex supplement should be taken every morning. The nutritional drink mix and the vitamin B complex supplement will ensure that your body has all the vitamins, minerals, amino acids, and other nutrients to combat your fatigue. Taking a daily adrenal supplement, like the one discussed earlier, will provide the much needed (and often depleted) nutrients your body may be lacking, and help you recover lost energy. Rhodiola rosea, and ginseng can offer additional natural nutritional support in your busy life to boost your energy levels. These nutritional supplements can be used daily and you will feel energized to get through each day’s challenges and opportunities!



--
Buy Energy and Stress Formulas at Vitanet Health Food Store ®

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Chronic Fatigue Syndrome and Fibromyalgia
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Date: February 28, 2007 12:02 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Chronic Fatigue Syndrome and Fibromyalgia

This is a fast paced world. We are all busy; living our full lives, burning the candle at both ends. We all get tired. We all get sick from time to time and maybe even depressed. But the illness called chronic fatigue syndrome is not like the normal ups and downs that we experience in everyday life. People with chronic fatigue syndrome feel overwhelming fatigue, and often pain as well. This is an illness that does not go away with a few good nights’ sleep. It drags on and on and doesn’t resolve itself. It steals vigor and energy over months, and sometimes even years.

In this issue of Ask the Doctor, we will talk about powerful vitamins, minerals, amino acids, and herbs combined in scientifically validated formulas that people with chronic fatigue syndrome or fibromyalgia can use every day. These nutrients help address some root problems of chronic fatigue syndrome and fibromyalgia by restoring energy and health to sufferers.

Q. What is chronic fatigue syndrome?

A. Chronic fatigue syndrome (CFS) also known as chronic fatigue and immune dysfunction syndrome (CFIDS), or myalgic encephalomyelitis (ME), is a group of symptoms associated with unrelenting and debilitating fatigue. The profound weakness of CFS causes a persistent and substantial reduction in activity level. You feel too tired to do normal activities or are easily exhausted for no apparent reason.

Besides extreme fatigue, symptoms of CFS include general pain, mental fogginess, flu-like symptoms, and gastrointestinal problems. A list of symptoms includes:

  • -Headache
  • -Frequent infections, such as sinus or respiratory infections, swollen glands, bladder infection or yeast infections
  • -Muscle and join aches
  • -Inability to concentrate or “brain fog”
  • -Allergies to foods and medications
  • -Anxiety and depression
  • -Decreased sex drive

The number of symptoms and the severity of these symptoms can vary among people. The symptoms of CFS hand on or reoccur frequently for more than six months.

Q. Are chronic fatigue syndrome and fibromyalgia considered being the same illness?

A. Fibromyalgia syndrome (FMS) is a painful shortening of muscles throughout the body. FMS is basically a sleep disorder characterized by many tender knots in the muscles. These tender knots, called tender or trigger points, are a major cause of the achiness that people with fibromyalgia and CFS feel.

Approximately 80 percent of chronic fatigue syndrome patients have received and overlapping diagnosis of fibromyalgia syndrome. For most people, fibromyalgia and chronic fatigue syndrome are the same illness.

Q. What causes chronic fatigue syndrome?

A. There are many causes that can trigger CFS. Current research is looking at the roles of neuroendocrine dysfunction, viruses, environmental toxins, genetic predisposition, food sensitivities, yeast overgrowth, faulty digestion, or a combination of these factors.

For many people, CFS is triggered by a bout with a viral illness (like a cold or the flu), or even a stressful event. CFS is usually a mix of underlying causes. It is like a domino effect in that each problem can trigger another problem, and so on. For example, fatigue and poor sleep can trigger a weakened immune system, which can, in turn, trigger yeast or bacterial infections.

Q. Who gets chronic fatigue syndrome?

A. CFS is more common than you might expect. It strikes people of all ages, racial, ethnic, and socioeconomic groups. Approximately 800,000 people nationwide have CFS and over six million have fibromyalgia at any given time.

It is important to stress that CFS is a real illness; it is not “just in your head.” Unfortunately, sufferers of CFS may find that many healthcare practitioners discount the symptoms of this illness or misdiagnose it as another disease. This can lead to additional emotional suffering.

Q. How long does chronic fatigue syndrome last?

A. The illness varies greatly in its duration. Some people recover after a year or two. More often, those who recover are more likely to do so three to five years after onset. Yet for some people, the illness seems to simply persist. There are rare cases of spontaneous improvement after five years without undergoing any treatment. However, this is very unusual.

Q. What are the complications of chronic fatigue syndrome?

A. The patterns of CFS vary from individual to individual. However, many common patterns of symptoms are seen in CFS sufferers. These symptoms and problems interact and create new symptoms and problems. For example, infections and disrupted sleep can lead to digestive, hormone, and immune problems.

Infections

The most notorious pattern seen in CFS is the one in which a person suddenly comes down with a flu-like illness that doesn’t go away. These viral or bacterial infections can suppress the body’s master gland, the hypothalamus. Since the hypothalamus controls the other glands, including the adrenals, ovaries, testes, and thyroid, suppression of this gland will lead to a subtle but debilitating decrease in the functioning of all glands and their hormones. Suppressed hypothalamic function from chronic infections can then trigger sleep dysfunction.

Disrupted Sleep

The suppression of the hypothalamus gland can lead to poor sleep because the body confuses its day/night cycles. Because of this, people with CFS have trouble staying in the deep, restorative stages of sleep that “recharge their batteries.”

Poor sleep can cause immune suppression, which may lead to secondary bowel infections. The bowel infections seen in people with CFS can cause decreased absorption of nutrients, which can lead to chronic vitamin and mineral deficiencies.

Q. Is there a cure for chronic fatigue syndrome?

A. Treating chronic fatigue syndrome presents a significant challenge to people with CFS and their healthcare practitioners. Recently, a published placebo-controlled study ( of which I was the lead investigator) showed that when using an integrated treatment approach, over 85 percent of CFS and fibromyalgia patients can improve, often dramatically. The full text of this study can be seen at ‘www.endfatigue.com’. An editorial in the April 2002 issue of the Journal of the American Academy of Pain Management noted that this treatment, which I developed, is now a highly effective and excellent part of the standard of practice for treatment of fibromyalgia. Since this treatment addresses many different problems associated with CFS/FMS, it needs to be individualized to each patient.

Medical Treatments

Medications that provide symptom relief are frequently the first line of treatment chosen by healthcare practitioners for the person with CFS. These include medications for pain, sleep disturbances; digestive problems such as nausea, depression and anxiety, and flu-like symptoms.

However, medications have not been universally successful because they tent to put a bandage on symptoms instead of addressing the root problems. Because of this, medications may need to be supplemented by the other supportive therapies that can address the root problems.

Supportive Treatments

People with CFS/FMS may be depressed, given the catastrophic lifestyle disruption these diseases may cause. They may also feel guilt and frustration because their symptoms were not taken seriously for such a long time. Fear can be a factor as employment and family relationships may be jeopardized by this illness.

Therapies that help people to relax and improve coping skills may be helpful and include counseling for emotional and mental health, cognitive behavioral therapy, sleep management therapy, and massage.

Daily Nutritional Supplementation for Energy

Good overall nutrition is important for everyone, of course. However, there are several vitamins, minerals, and amino acids that can have powerful nutritional effects for a person with CFS. All of the vitamins and minerals in a chronic fatigue/fibromyalgia formula should work together synergistically to help improve energy levels and overall health. Here are some key nutrients to look for in an energy formula:

Vitamins, Minerals & Other Key Ingredients

Vitamin A: Essential for healthy skin and mucous membrane integrity, healthy immune system responses and healthy bone growth and healthy reproductive processes. Vitamin A in the form of beta-carotene is an antioxidant and free radical fighter. Vitamin E: Helps to relieve pain in CFS patients. Can also improve night leg cramps, which interferes with sleep.

Vitamin C: Enhances immune function by increasing natural killer cells, B and T cells. Can prevent chronic bladder infections by acidifying urine.

Vitamin D: Regulates immune functions of monocytes and neutrophils. Neutraphils are white blood cells that ingest invasive bacteria, and act as the first line of defense once bacteria makes it past the skin barrier.

Magnesium: Involved with immune support. Working with malic acid, enhances immune function by increasing natural killer cells. Magnesium is also critical for the relief of muscle pain.

Inositol: Enhances immune function by increasing natural killer cells.

Malic Acid: Working with magnesium, improves energy levels by improving cellular functions. Especially important in muscle metabolism.

Betaine: Works with B vitamins to synthesize amino acids, and acts as a precursor to SAM-e. SAM-e (S-adenosylmethionine) is a naturally-occurring molecule in the body, and may have an effect on overall mood elevation.

Amino Acids: Glycine, Serine, Taurine, Tyrosine are essential for the production of energy in the body. Also essential for brain function.

Zinc: Supports the immune system by enhancing neutrophils activity and supporting healthy antigen-antibody binding.

Selenium: Supports immune function by enhancing antibody production.

Fructooligosaccharides: Provides nutrition for good bacteria in the intestinal tract, improving digestion and healthy microflora.

All of the vitamins, minerals, and other nutritional supplements on the list are important to ensure recovery from chronic fatigue syndrome. To ensure that your nutritional supplement regimen contains all of these ingredients, look for a powdered supplement formulated specifically for CFS/FMS sufferers that can be reconstituted in a beverage of your choice. A powdered drink mix is a pleasant, easy way to ensure that you are taking all of the needed vitamins, minerals, and amino acids that will give you the needed energy to recover from your illness.

B Vitamin Complex for Energy

In addition to the powdered energy drink mix, it is important that you also take a vitamin B-complex supplement specifically formulated for people with CFS/FMS. The B vitamin formula, which should include niacinamide, thiamin, riboflavin, vitamin B6, folic acid, vitamin B12, pantothenic acid, and choline, is especially important to restore the energy production needs of your body, as well as for mental function. It is also important to make sure that the dosages are high enough CFS/FMS needs. The chart in the next column lists the B vitamins that are critical for people suffering from CFS/FMS.

B Vitamins Effect on Chronic Fatigue Syndrome

Studies have demonstrated that people with CFS/FMS are often deficient in many of the B vitamins, which tends to worsen their symptoms of fatigue and mental “fogginess” and ultimately lead to a weakened immune system.

B vitamins - Effect on Energy

Thiamine (B1) - Essential in the process of energy production. This vitamin also removes lactic acid from muscles, which causes them to be sore in fibromyalgia patients.

Riboflavin (B2) - Riboflavin (vitamin B2) is crucial in the production of body energy. Supports healthy gluthathione reductase activity, which helps maintain gluthathione, a major Protector against free radical damage. Vitamin B2 itself also has antioxidant qualities.

Niacinamide(B3) - Essential vitamin that is a component of the body’s energy furnace, helping to improve fatigue and “brain fog”.

Pantothenic Acid (B5) - This vitamin improves adrenal gland function, which will boost energy levels. It can also aid in weight loss by decreasing appetite.

Vitamin B6 - Working along with thiamine, this vitamin is critical in the process of energy production.

Vitamin B12 - Important for brain function and nerve repair. Aids in relieving fatigue symptoms in CFS patients. Folic Acid - Aids in strengthening the immune system, and aids in mental clarity and concentration.

Q. What other supplements can help me with CFS?

A. Many people with CFS/FMS are suffering from adrenal burnout. Adrenal burnout occurs when the adrenal glands are constantly producing cortisol in response to chronic stress like that seen in cases of CFS. Over time, this exhausts the adrenal reserve, meaning the adrenal gland can no longer increase cortisol production in response to stress.

The good news is that changes in our hormone levels can return to normal when stress is decreased. However, in cases of CFS that return to normal can be made much simpler by using a glandular therapy regimen to ensure healthy cortisol levels and adrenal function.

Glandular therapy uses the concentrated forms of bovine (cow) or porcine (pig) glands to improve the health of our glands. Pioneers in the field of endocrinology (the study of hormones) hypothesized that glandular extracts work by providing nutrients the body lacks and thus repairing the malfunctioning gland.

Adrenal Extract

If CFS has left your adrenal glands in a stressed-out state, you should see great results by taking adrenal supplements. Be sure to buy an adrenal extract supplement that contains both whole adrenal and adrenal cortex extracts.

The best adrenal supplement should also contain vitamin C, vitamin B6, L-tyrosine, betaine, pantothenic acid and licorice. Licorice contains glycyrrhizin, which is broken down into glycyrrhizic or glycyrrhetinic acid. This compound inhibits the activity of an enzyme that turns active cortisol into inactive cortisol. While in high amounts (greater than 100 mg of glycyrrhizic acid/day), licorice administration causes hypertension, no such effects have been observed at lower doses. Experts have speculated that inhibition of the cortisol-converting enzyme may reduce cortisol-related symptoms associated with adrenal insufficiency. The adrenal glands use these nutrients to manufacture cortisone and other compounds. It just makes sense to purchase an adrenal supplement with these supportive ingredients.

The Road to Recovery-Adequate Sleep

Disordered sleep is the underlying process that drives many of the symptoms of CFS/FMS. The most effective way to eliminate pain in CFS/FMS is to get seven to nine hours of deep sleep each night.

However, getting adequate sleep is easier said than done for CFS sufferers with underlying fibromyalgia symptoms. The muscle knots of fibromyalgia make it uncomfortable to lie in one position for an extended time, causing difficulty in returning to deep sleep. Because of this, people with CFS/FMS do not stay in deep stages of sleep to recharge their “batteries.” In addition, poor sleep can cause and be caused by the suppression of the hypothalamus gland, which causes the brain to think it is daytime instead of night time.

It may be helpful to use herbal products to promote good quality sleep. There are many natural supplements that are marketed as sleep formulas. To get the best results, it is very important that the right ingredients are in the sleep formula you buy. Therefore, it is important to look for an herbal sleep formula that is especially formulated for people with CFS/FMS. The combination of herbs is important as each herb addresses a different aspect of sleeplessness and muscle tension.

Ingredients - Effect on Sleep

Wild Lettuce - Has been found to have sedative effects.

Hops - Acts as mild sedative and has a sleep-inducing effect. Jamaica Dogwood Has been found to be mildly sedative and is often used for anxiousness.

L-Theanine - Causes significant increases of neurotransimitter concentrations in the brain, which promotes muscle relaxion and improves sleep.

Valerian - This herb has been clinically studied for its ability to improve sleep quality.

Passionflower - This herb eases nervousness and insomnia.

Putting It All Together

After a good night’s rest, a powdered energy drink mix formulated for people with CFS/FMS should be drunk along with a well-balanced breakfast as discussed earlier. In addition to the nutritional beverage mix, a vitamin B complex supplement designed specifically for CFS sufferers, also discussed earlier, containing niacinamide, thiamin, riboflavin, vitamin B6, vitamin B12, pantothenic acid, and choline, should be taken every morning. The nutritional drink mix and the vitamin B complex supplement will ensure that your body has all the vitamins, minerals, amino acids, and other nutrients, to combat your overwhelming fatigue, pain, and “brain fog.” Taking a daily adrenal supplement, like the one discussed earlier, will provide the much-needed (and often depleted) nutrients your body may be lacking, and help you recover lost energy.

Together, these four interventions: sleep formula; morning energy drink; energy B complex supplement; and an adrenal complex- can make an incredible difference that you should begin to notice within 2-3 weeks of starting this program.

Conclusion

Chronic fatigue syndrome and fibromyalgia are complex physical diseases with physical causes. The unrelenting symptoms of fatigue, pain, and mental fogginess can be overwhelming and frightening. Partnering with a healthcare practitioner specializing in CFS and utilizing different medical treatments, supportive therapies, and lifestyle changes are healthy ways to combat chronic fatigue syndrome. And taking nutritional supplements formulated specifically for people with CMS/FMS that help boost energy or help you get a good night’s sleep can give you critical control over the outcome of your illness and set you on the road to recovery.



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Benefits of Camu Camu Powder Extract
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Date: August 29, 2006 09:18 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Benefits of Camu Camu Powder Extract

Benefits

100% Natural Wild-Crafted Vitamin C*

Camu camu is one of the richest natural sources of this potent antioxidant vitamin in the world. Every gram of Best Camu Camu 4:1 extract contains at least 200 mg of natural, wild-crafted vitamin C. This is in addition to a synergistic host of additional nutrients that potentially enhance the uptake of the antioxidants in the extract.

Vitamin C is critical to numerous organs and systems throughout the body. It serves as an important cofactor in a number of physiological processes that occur on a daily basis. Vitamin C protects molecules including lipids, proteins and DNA from free radical damage and serves to regenerate other potent antioxidants, including vitamin E. Vitamin C is also a required factor for the synthesis of collagen and connective tissue, plays a prominent role in energy production, helps in the formation of the neurotransmitter norepinephrine, and supports immune health.1 An adequate daily supply of vitamin C is necessary for the maintenance of these and other critical physiological processes.

Strengthens Antioxidant Defenses*

Anthocyanin compounds, such as cyanidin-3-glucoside found prominently in camu camu fruit, are natural pigments responsible for the brilliant colors seen in fruits.2 They also possess significant antioxidant activities as well as other potential health benefits. Furthermore, studies show that anthocyanin compounds are rapidly absorbed in humans and other mammals. Recent studies have shown that the stomach and small intestines are the predominant sites of absorption into the bloodstream.3

Research conducted on cyanidin-3-glucoside confirms its potent antioxidant activity. In vitro assays have been performed evaluating markers of free radical damage including DNA cleavage, free radical scavenging capacity and xanthine oxidase activity. In this study, cyanidin-3-glucoside showed protective effects on DNA cleavage, inhibition of xanthine oxidase and dose-dependent free radical scavenging abilities.4 Studies in rats also confirm the beneficial effects of this anthocyanin. In one such study, feeding this compound to rats was shown to increase the resistance of rat serum to oxidative changes, suggesting a potent antioxidant effect of this compound.5

Camu camu is a potent source of cyanidin-3-glucoside and has a high content of the ubiquitous, water-soluble antioxidant, vitamin C. Together, these nutrients serve to strengthen antioxidant defenses against free radical damage*. Best Camu Camu 4:1 Extract provides a natural, wholesome way to infuse the body with its daily requirement for vitamin C and additional free radical-fighting anthocyanin compounds.

Safety

Suggested Adult Use: Take 1 more capsules daily, with or without food

Scientific References

1. Linus Pauling Institute. Micrnutrient Information Center. Monograph on “Vitamin C”. //lpi.oregonstate.edu/infocenter/vitamins/vitaminC/

2. Zanatta CF, et al. Determination of Anthocyanins from Camu-camu (Myrciaria dubia) by HPLC-PDA, HPLC-MS, and NMR. J Agric Food Chem 2005. 53: 9531-9535.

3. Talavera S, et al. Anthocyanins are efficiently absorbed from the small intestine in rats. J Nutr 2004. 134: 2275-2279.

4. Acquaviva R, et al. Cyanidin and cyanidin 3-O-beta-D -glucoside as DNA cleavage Protectors and antioxidants. Cell Biol Toxicol. 2003 Aug;19(4):243-52.

5. Tsuda T, et al. Dietary cyanidin 3-O-beta-D-glucoside increases ex vivo oxidation resistance of serum in rats. Lipids. 1998 Jun;33(6):583-8. Buy Camu Camu at Vitanet

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Hayfever & Allergies - Herbs To Help You Breathe Easier
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Date: June 30, 2005 09:36 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Hayfever & Allergies - Herbs To Help You Breathe Easier

Hayfever & Allergies By Ellen J. Kamhi, Ph. D. with Dorie Greenblatt Runny nose, watery eyes, itchy skin...oh no, it's that time of year again! Are you one of the 30 million Americans who suffer from hayfever? If so, breath easier and let the herbal world replace your antihistamines and steroids with both preventative and therapeutic remedies.

Allergies and hayfever are abnormal reactions to everyday substances such as pollen, dust, dander, etc. and involve many different organ systems of the body, primarily the respiratory, liver and adrenal glands. Using herbs to strengthen these systems will give your body a preventative edge over allergic reactions, and will further help decrease the severity of uncomfortable symptoms.

Licorice is a wonderful ally to the adrenal glands and is probably the most widely studied adrenal herb. Licorice has anti-inflammatory actions similar to the glucocorticoids (which are produced by healthy adrenals) and are involved with resolving allergic reactions. It also preserves the effects of cortisol, and adrenal hormone involved in clearing allergies.

A second well-known herb used to strengthen the adrenals is Ginseng. Often times, the onset of allergies can be attributed to stress. The adaptogenic properties of Ginseng allow the glands to balance stress and energy while creating an overall resistance to allergic reactions, colds, flus and infections.

A strong liver is also vital to a healthy balanced body, acting as a protective factor against allergies. Dandelion is one of the most nutritive and strengthening herbs to the liver. It helps clear toxins and stimulates the energy of the liver to work towards the resolution of the allergic reaction. Milk Thistle acts as both a Protector and regenerator of the liver. This herb helps repair damaged tissue and support the actions necessary for dealing with allergens and their accompanying symptoms.

When confronted with the copious secretions commonly experienced by allergy sufferers, Nettles and Eyebright are two of the best herbs to choose to control the "drip". Both work well for short-term relief, but may be taken before the season begins as a means of prevention. For those people who become congested and need a remedy which allows them to breathe while draining occurs, Ma Huang is a good choice. Due to its stimulating nature, use Ma Huang with caution if you have high blood pressure, heart disease, etc. Additional herbs suitable for allergy relief include Red Clover, Elder Flower and Bayberry.

For a potent synergistic formula, try Allertone. This outstanding product featrues a blend of the well-known Echinacea and Goldenseal, along with Red Clover, Bayberry and Mullein to combat both the discomfort of allergies as well as reduce excess mucous from the nasal and respiratory tract.

  • These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure or prevent any disease.

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    Vitanet ®

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    Improove Memory ...
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    Date: June 09, 2005 05:49 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Improove Memory ...

    Mesmerizing Memory by Cal Orey Energy Times, January 1, 1999

    In the 60s, the same rock 'n' rollers who belted out "One pill makes you larger and one pill makes you small," often espoused the belief that certain pills could expand the mind. While counter-culture pill purveyors were pilloried for their pill-popping claims, 90s nutritional research has uncovered a stash of supplements that may amplify mental improvement.

    Like a blues singer bending a high note, researchers are now humming with dramatic assertions that certain nutritional supplements can sustain and enhance concentration and memory function. For instance, studies reveal possible benefits for cognitive powers from vitamin C, magnesium and Ginkgo biloba. A recent report in the Journal of the American Medical Association (JAMA 278:1327-1332) said that an extract of Ginkgo biloba "can stabilize and, in some cases, improve the cognitive function and social behavior of demented patients."

    A researcher in the Proceedings of the National Academy of Sciences noted that a daily dose of vitamin E may "help protect the brain and its memories from the ravages of time." And the beat goes on: other evidence indicates that zinc, iron and boron may pump up short-term memory attention span and cut the time it takes to perform mental tasks.

    Neuronutrients
    Neuronutrients-mentally helpful vitamins, minerals, fatty acids, amino acids and trace elements-offer an exciting key to keeping mental functions from succumbing to the degenerations of aging and disease. According to Dharma Singh Khalsa, MD, author of Brain Longevity (Warner Books) and an energetic campaigner for mental fitness through nutrition and exercise, vitamin E "can not only prevent deterioration of the brain, but actually reverse an important element of deterioration." Dr. Khalsa describes vitamin E as one of the most potent antioxidants, a fighter of the electrically charged free radicals that attack and break down cell membranes and nerve endings.

    Lester Packer, PhD, professor of molecular and cell biology at UC Berkeley, told a joint 1996 United Nations-World Health Organization conference on Aging that "there is a growing body of evidence indicating that the free radical theory of aging and aging-related disease is valid," and that dietary and supplemental antioxidants can help fight illness and mental deterioration.

    Vitamin E and other memory aids are believed to protect brain chemicals called neurotransmitters, "the ferrymen of the brain's communication system," that influence concentration and memory. Experts say that sustaining the level of these nerve chemicals in the brain can potentially improve all mental processes.

    Brain Well-Being
    "Your brain is intricately bound up with your physical state of well-being and is, therefore, vulnerable to any kind of physical abuse, especially that of chemical or substance abuse," report Thomas H. Crook III, PhD, and Brenda Adderly, MHA, co-authors of The Memory Cure (Pocket Books).

    Too much alcohol, for example, commonly causes progressive mental decline, according to Secrets of the Superyoung (Villard) by David Weeks and Jamie James. The authors also point out that "the memory tends to worsen noticeably after 15 years of alcohol drinking, and much sooner in people who go on massive binges."

    "The effects of cigarette smoke are subtler because the poisonous effects of carbon monoxide in each puff are temporarily offset by the alerting effects of the nicotine," they add. Can't remember the name of that singer cavorting in a music video? Tests have shown that smokers are worse at connecting peoples' names to their faces than nonsmokers.

    Cognition Ignition
    A first step in beginning your brain-boosting regimen consists of intensified intellectual activity, insists Rebecca Rupp, writer of Committed to Memory: How We Remember and Why We Forget (Crown): n Keep working: The mental challenges and social interactions of a job prevents lapses in the brain's synapses.

    n Learn something new: A second language, musical instrument, or unique puzzles and games keep neurons working like new.

    n Turn off the TV: Read. Studies show that passively watching TV requires less concentration than eating cereal. Mental rejuvenation also requires physical activity. Exercise increases oxygen flow to the brain, which supports memory, concentration and cognition. One study has shown that exercise significantly brightened the moods of middle-aged and older women, regardless of whether they were pre- or post-menopausal, with or without hormone replacement therapy.

    Supplemental Brain Help
    As you provide for your physical and mental vitality through healthy exercise and diet, you can augment your regimens with other supplements that research has shown to boost brain power.

    Antioxidants, including the previously mentioned vitamin E (You haven't forgotten vitamin E already, have you?), provide crucial help for vigorous cerebral function. The free radicals created by tobacco smoke, air pollution, ultraviolet light and certain carcinogenic chemicals deconstruct cell membranes and may foster microscopic brain cell havoc. Antioxidant enzymes convert free radicals to more neutral, benign substances and nutritional antioxidants can neutralize free radicals by linking up with them.

    Vitamin C, a brainy antioxidant all star, performs so well that, according to Dr. Khalsa, its levels in the brain are almost 15 times higher than in other parts of the body. This nutrient, he asserts, aids mental and physical longevity. In a UCLA study, people who ingested at least 300 mg of vitamin C daily lived more than six years longer than those who ingested less.

    Mental Fat
    As a brain Protector, selenium ranks high. Your brain consists of about 60% fat and selenium is a master at restricting detrimental fat oxidation. At the same time, zinc takes part in antioxidant processes that quell free radicals and strengthens neuronal cell membranes, protecting nerves from damage.

    Added to this mix, magnesium also scavenges free-radicals, according to Dr. Khalsa. Plus, experts recommend grape seed extract (phytochemicals that protect a wide range of cellular structures) to safeguard nerve cells and mental capacity.

    B Vitamins for the Mind
    John W. Rowe, MD, president of Mount Sinai Hospital and School of Medicine in New York and author of Successful Aging (Pantheon) states that "there is a significant relationship between blood levels of folic acid and vitamins B12 and cognitive decline." In other words, these vitamins seem to be necessary to eliminate a protein called homocysteine, which has been implicated in the development of coronary heart disease and cognitive problems. (Support for Dr. Rowe's conclusion appeared in the American Journal for Clinical Nutrition 63-306.)

    Iron Mind
    Iron also may strengthen memory. Since iron is involved in distributing oxygen to brain cells (and every other cell in the body), when you lack this mineral you may find it hard to concentrate. In the early 1990s, Harold Sandstead, MD, professor of preventive medicine at the University of Texas, discovered that women whose diets lack zinc and iron experienced more difficulties on standard exams than women with an adequate dietary supply. In his study of women aged 18 to 40, Sandstead found that giving these women more zinc and iron raised their scores on memory tests and average of 20%.

    Boron plays a crucial part in mental function. Scientists at the USDA's Human Nutrition Research Center have linked boron deficiencies to chronic lethargy and fatigue. In brain studies, they found that the electrical activity of the gray matter in the boron deficient indicated increased drowsiness and mental sluggishness.

    Huperzine Boost
    Borrowed from Chinese folk medicine, Huperzine A (HupA) recently has attracted attention from researchers who credit it with enhancing cognitive function and helping folks suffering from disease-related dementia. HupA is an extract of the club moss Huperzia serrata and has been used for centuries in China to treat fever, inflammation and, most recently, dementia. Dr. Alan Kozikowski, professor of chemistry in the neurology department at Georgetown University's Drug Discovery Program, a researcher who first synthesized HupA and studied it extensively, reported in the Journal of the American Medical Association (JAMA, 277 (10):776-March 1997), that HupA is safe, having been used to treat 100,000 people in China.

    HupA basically protects the brain from free radical damage (due to low levels of antioxidant defenses) and maintains or enhances crucial neurotransmitter action. More specifically, HupA helps reduce the breakdown of acetylcholine, the vital neurotransmitter, and makes this substance more bioavailable. In addition, HupA helps make choline accessible to the brain for the synthesis of acetylcholine, according to a study in Neuropharmacology (30, 1991: 763-768).

    Normally, the brain manufactures sufficient levels of the chemical phosphatidylserine, a lecithin-derivative that helps boost neurotransmitter release, but deficiencies of vitamin B12 and folic acid, or of essential fatty acids, may retard that production. Low levels of phosphatidylserine in the brain are related to impaired mental function and depression in the elderly. Scientists reporting in Aging (5, 1993; 123-33) describe "good results" using phosphatidylserine in the treatment of age-related cognitive ills.

    Ginkgo Brain Power
    Researchers also have demonstrated that Ginkgo biloba extract (GBE) increases brain function mostly by boosting acetylcholine receptors and the transmission of nerve impulses, with no significant adverse reactions. GBE is effective not only for folks with Alzheimer's; it also helps when mental function is impaired by vascular deficiencies or depression. Keep in mind that experts believe that GBE requires about 12 weeks of supplementation to reach optimal effectiveness.

    Another ingredient in what seems like an alphabet-soup of brain nourishment is DHA (docosahexaenoic acid), an omega-3 fat essential for normal brain function. Researchers met recently at The New York Hospital-Cornell Medical Center's Nutrition Information Center to discuss "Keeping Your Brain in Shape: New Insights into DHA." Their findings revealed links between low levels of DHA and Alzheimer's, depression, memory loss, attention-deficit/hyperactivity disorder (ADHD) and certain behavioral traits including aggression and hostility.

    Mostly Fat
    Since so much of the brain is fat, material like DHA forms the building block of brain tissue and the primary structural fatty acid in its gray matter. Although it is critical for mental and visual well being, the average American's consumption of DHA has declined since we're eating less of DHA's dietary sources: animal organ meats and eggs.

    Researchers from the National Institutes of Health point out, however, that fish is an excellent dietary source of DHA. In their studies, they discovered that depression rates in Japan and Taiwan, where fish ranks a top spot on the menu, are significantly lower than in North America and Europe.

    DHA also is crucial to the neurological development of children, according to findings published in Pediatrics (vol. 101, no. 1, January 1998). Researchers suggest that DHA-rich breast milk should be the model for infant formulas that enhance babies' neurological development. Scientists also have correlated some behavioral problems in children-ADHD, for example-to DHA deficiencies.

    If you are a vegetarian, or have other cause for concern about a potential lack of DHA in your diet, you can rely on dietary supplementation of DHA. Bruce J. Holub, PhD, of the University of Guelph in Canada provided vegetarians in his research project with DHA supplements over a 42-day period and substantially increased their DHA blood levels.

    The bottom line to enhanced mental performance is to take a balanced approach, says Robert Snider, MD, who specializes in preventive medicine in Massena, New York. "Maintaining brain power includes exercise, stress reduction and good nutrition." The message to keep in mind: Don't lose your nutritional balance or you could lose a piece of your peace of mind.

    Recommended Reading: & Brain Builders (Reward Books, 1995), by Richard Leviton.

    Brain Longevity (Warner Books, 1997), by Dharma Singh Khalsa, MD.

    Omega 3 Oils to Improve Mental Health, Fight Degenerative Diseases and Extend Life (Avery, 1996), by Donald Rudin, MD, and Clara Felix.

    Successful Aging (Pantheon, 1998), by John W. Rowe, MD, and Robert L. Kahn, PhD.



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    Pycnogenol Complex - The Next Generation of Antioxidant Protection
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    Date: June 04, 2005 02:14 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Pycnogenol Complex - The Next Generation of Antioxidant Protection

    Pycnogenol Complex

    If there’s one factor that has the greatest negative impact on our health, it is the damage done to our cells by free radicals. These highly unstable molecules disrupt the biochemical processes that regulate life. Although a natural product of oxygen metabolism in the body, free radicals are also produced in vast quantities by modern technology. Our bodies’ natural defenses simply have not been able to keep up with the onslaught of these dangerous products of civilization. On the other hand, technology has offered help by identifying some of nature’s most powerful weapons against free radical attack. Source Naturals PYCNOGENOL® COMPLEX is an unprecedented combination of these extremely potent plantbased antioxidants, or Plantioxidants™. Consider them your antidote to the industrial revolution.

    How free radicals are formed and their effect on the body

    Oxygen both makes life, and takes life. The energy that animates us comes from the biochemical reactions that burn oxygen within our cells. And though carefully regulated by the body, this biological combustion, over time, inevitably leads to cellular damage. If oxidation is not carefully controlled, tissues are damaged faster than the body can repair them. This is caused by an excess of over-reactive, electron hungry molecules called oxidants or “free radicals,” which tend to disrupt normal cellular activity. Free radicals attack a cell’s membrane and can even damage its hereditary blueprint (DNA). Since free radicals are a natural result of certain metabolic reactions, the body synthesizes several types of antioxidant enzymes to neutralize them. In addition, we get essential antioxidants from the foods we eat. Vitamins C, E and beta carotene are the ones found most often in our diet. During this century, our environment has become a perpetual source of free radical contamination, primarily from radiation and the chemical pollution in our air, water and food. Today, we are literally overwhelmed with more free radicals than our bodies are accustomed to handling. Fortunately, science has found that certain plants contain special antioxidants that are far more powerful than the vitamins we typically get in our diet. With this knowledge, Source Naturals formulated PYCNOGENOL® COMPLEX, the most advanced combination of Plantioxidants available today in one product. Pycnogenol® is the proprietary name of a natural plant product made from the bark of the European coastal pine, Pinus maritima.

    Natural protection against free radicals

    Pycnogenol® Complex – A Cornucopia of Health Our knowledge of pine bark goes back nearly 500 years, to when the French explorer, Jacques Cartier, reported that a tea made from pine tree bark by Native Americans saved the lives of his crew who were dying of scurvy. Nutrition scientists have since isolated the extraordinary antioxidant compounds of pine bark. They have also discovered many other unique antioxidants throughout the plant kingdom. Plants have evolved bioflavonoids to protect themselves from free radical damage. One of the most abundant compounds in the plant kingdom, bioflavonoids are found in the pigments of bark, rinds, seeds, leaves and flowers.

    Natural antioxidants in Pycnogenol® Complex

    The active ingredients of Source Naturals PYCNOGENOL® COMPLEX are derived from a diverse range of nature’s plenty: pine bark, green tea, turmeric spice, rosemary, grape seeds, milk thistle seeds, bilberries, hawthorn berries and ginkgo leaves. Each of these Plantioxidants is an exceptional free radical scavenger, and each has a tendency to concentrate in a different organ of the body, thus providing targeted protection. And since their primary function is to capture free radicals, these Plantioxidants free up vitamin C, so it can perform its many other vital functions.

    Defense Plants The two headliners of Source Naturals PYCNOGENOL® COMPLEX are the pine bark extract, Pycnogenol®, and an extract from grape seeds, Proanthodyn™. Their unsurpassed antioxidant activity – up to 20 times that of Vitamin C and up to 50 times that of Vitamin E – comes from a high concentration of proanthocyanidins.

    Why Pycnogenol® Complex is formulated with extracts of pine bark and grape seed

    These highly bioavailable flavonoids are able to cross the Blood-Brain Barrier, and can stay in the bloodstream for up to 72 hours. Few other nutritional antioxidants cross this barrier, and none do it as well. Proanthocyanidins therefore offer the brain and central nervous system unparalleled antioxidant protection. In particular, proanthocyanidins may help reduce the formation of lipofuscin, a brown waste material made of free radical-damaged proteins and fats. Over time, lipofuscin deposits form in the brain, heart, and skin. The “age” or “liver” spots that develop on the backs of some elderly peoples’ hands are made of lipofuscin. Because they’re rich in unsaturated fatty acids, cell membranes are the primary site of free radical attack. Proanthocyanidins are able to protect against both water- and fat-soluble free radicals. Also, their chemical structure is incorporated within cell membranes, making proanthocyanidins very effective in preventing damage to the cell’s interior. This is vital, because if a cell’s DNA is disrupted, it could lead to the abnormal reproduction of that cell. For many years now, Europeans have used pine bark and grape seed extracts to maintain vein and capillary health. Proanthocyanidins support the circulatory system by helping to keep collagen and elastin, the essential constituents of vessel walls, from breaking down during times of imbalance. And most importantly, proanthocyanidins can help prevent the oxidation of LDL cholesterol in the bloodstream. Scientists now recognize that it’s not cholesterol itself, but the oxidation of cholesterol that can be problematic.

    How Plantioxidants benefit different organs in the body

    The Power of Diversity

    In addition to the broad protection offered by Pycnogenol® and Proanthodyn, Source Naturals PYCNOGENOL® COMPLEX offers an outstanding array of other Plantioxidants. Each has unique abilities to protect the body from oxidants. For several thousand years, Green Tea has been enjoyed in the Orient, not only for its taste, but also as a health tonic. Upon analysis, it contains several strong antioxidants, called Polyphenols, with exceptional free radical scavenging abilities. Polyphenols have been shown to be over 200 times more effective than vitamin E in preventing oxidative damage to brain cells. Source Naturals uses a potent extract of green tea that concentrates 2,000 pounds of fresh green tea leaves into one pound of finished product. This extract has been awarded 30 patents for its protective effects. The ancient Ginkgo Biloba tree has long been prized for its beneficial qualities. Like proanthocyanidins, ginkgo’s compounds are able to cross the Blood-Brain Barrier, and support cell membrane and capillary integrity. Its particular antioxidant constituents have been associated with superior oxygen transport to the brain. This is important because the brain uses 20% of all inhaled oxygen. Source Naturals PYCNOGENOL® COMPLEX uses a superior 50 to 1 extract, providing 24% Ginkgoflavoneglycosides and 6% Terpenoids. Bilberries were first studied for their capacity to heighten visual acuity in normal subjects under poor light conditions. In fact, to increase their night vision, RAF pilots ate bilberry jam during WW II. Its antioxidant compounds, Anthocyanosides, have an affinity for delicate eye tissues, where it quenches free radicals and supports capillary strength. Source Naturals utilizes a standardized bilberry extract with 25% anthocyanosides, 80 times more potent than regular bilberry.

    The wide range of natural antioxidants in Source Naturals PYCNOGENOL® COMPLEX

    Milk Thistle Seed Extract has been researched and used for over 20 years in Europe. Its antioxidant compound, called Silymarin, has a special preference for the liver. It’s one of the few nutrients that can support the liver’s natural regenerative processes. By enhancing DNA activity, liver cells can regenerate up to five times faster. Turmeric Extract contains 95% Curcumin, the active ingredient of this traditional East Indian spice. Curcumin promotes the body’s own production of antioxidant enzymes, including glutathione peroxidase, an important Protector of the liver. Curcumin also increases the production and secretion of bile, which is used to remove cholesterol from the body. Quercetin has been well-researched for its free radical scavenging activity. Because of its ability to stabilize cell membranes, quercetin helps prevent damage and discomfort from reactionary (histamine- and leukotriene-related) processes in the body. Source Naturals quercetin has been isolated from plant sources. Rosemary and Hawthorn Berries both contain bioflavonoid antioxidants that have the unique ability to neutralize the hydroxyl radical, a particularly dangerous type of free radical. Hydroxyls are produced by exposure to excessive radiation and pollution from burned fossil fuels. The body has no innate defense system against it. Vitamin C is one of the most active and abundant antioxidants in the body, so it must be frequently replenished. Since it works in conjunction with bioflavonoids, each tablet of Source Naturals PYCNOGENOL® COMPLEX contains 500 mg of vitamin C, bound to Magnesium for increased bioavailability.

    A World of Help

    As we better understand how free radicals affect our health and well being, it’s important that we take advantage of the wonderful protective qualities found in certain plants. These Plantioxidants provide the appropriate means to counteract the destructive effects of excessive free radicals, which have become part and parcel of modern life. Source Naturals PYCNOGENOL® COMPLEX brings the diverse and concentrated power of the plant world into your world of wellness.

    References
    • Masquelier, J. Natural Products as Medicinal Agents . Stutgart, Germany: Hippokrates Verlag, 1981. • Middleton, E. Jrnl. of Immunology 127 (1981): 546-50. • Muzes, G., et al. Acta-Physiologica-Hungary, 78.1 (1991): 3-9. • Oguni, I., et al. Orig. Res., Univ. of Shizuoka, Japan, 1990. PYCNOGENOL® is a registered trademark of Horphag Research, Ltd. Protected by U.S. Patent No. 4,698,360.



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    Neptune Krill Oil (NKO) - for Healthy Heart, Joints, and other Body systems
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    Date: June 03, 2005 05:43 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Neptune Krill Oil (NKO) - for Healthy Heart, Joints, and other Body systems

    Neptune Krill Oil

    Essential fatty acids are enormously important to your health. They are the building blocks for phospholipids, and phospholipids are the building blocks for your cell membranes – the protective layer and gatekeeper of your cells. A good essential fatty acid balance provides building blocks for healthy cells, but an imbalance can lead to critical health concerns. Source Naturals introduces NKO™ Neptune Krill Oil, the first product featuring phospholipids specially integrated with omega-3 essential fatty acids for building healthy cell membranes. It also includes antioxidant protection. In human studies, NKO supplementation supported healthy joints, the heart, lipid and blood sugar levels, energy production, athletic performance and liver function, and eased women’s PMS symptoms.

    Support Your Protective Cell Membranes

    Source Naturals brings you the science of natural NKO™ Neptune Krill Oil, the only product to boast significant healthinducing potencies from three different important nutritional categories: omega- 3 fatty acids, phospholipids and antioxidants. These three nutrients work together to support healthy cell membranes, joints, the heart and many other body systems. And NKO eases PMS symptoms for women.

    Multiple Benefits of Krill

    NKO™ Neptune Krill Oil has many benefits. Unlike fish oil products, NKO doesn’t contain dangerous levels of mercury or lead, doesn’t go rancid quickly and has a clean, fresh taste. Made from hearty krill, shrimp-like crustaceans that thrive in the harsh Antarctic waters, it is the only product to contain phospholipids specially integrated with omega-3 essential fatty acids. This unique structure provides important cell membrane building blocks in the ratios used by the body and may be far better utilized than stand-alone phospholipid or omega- 3 products. The result: stronger cell membranes that function better to maintain your health. The desirable composition of NKO, high in omega-3 essential fatty acids, also provides a healthy balance. High levels of omega-6 fatty acids, such as from processed foods, enable your cell membranes to initiate over-production of certain prostaglandins that can lead to cellular irritation, heart system imbalances and other concerns. But omega-3 fatty acids can reverse that trend. Omega-3 fatty acids such as DHA and EPA (docosahexaenoic and eicosapentaenoic acids) compete with arachidonic acid for building blocks, such as the COX-2 enzyme, and can instead lead to balanced levels of the many different types of prostaglandins. The result: cellular comfort, heart health and many other healthy body systems. NKO also contains natural antioxidants, which are cell membrane Protectors. Each serving contains 100 IU of vitamin A and a very high level, 1.5 mg, of astaxanthin, an immune-supporting carotenoid, which can be used to guard your cell membranes from free radical damage. And NKO 100% pure krill oil is manufactured by Neptune Technologies & Bioresources Inc. in adherence to all environmental harvesting standards. Source Naturals is pleased to partner with your local health food store to bring you NKO™ Neptune Krill Oil. Try this unique, potent and comprehensive product for your better health today.

    References
    Drevon, C. A. (1992). Nutr Rev. (50): 38-45. Horrobin, D. F. (1983). J Reprod Med. (28): 465-468. Simopoulos, A. P. (1991). Am J Clin Nutr. (54): 438-463.



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    Heart Science - A Five-Tiered Approach to Heart Health ...
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    Date: June 02, 2005 12:07 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Heart Science - A Five-Tiered Approach to Heart Health ...

    Heart Science 30 tabs

    Your heart is crucial to every function of your body. It is the sole organ which pumps oxygen-rich blood through the entire circulatory system, feeding your cells and making life possible. Only recently are Americans realizing the importance of a proper low-fat diet, regular exercise, giving up cigarette smoking, and cutting down alcohol consumption to maintaining a healthy heart. Unfortunately, there has been a huge gap in the number of nutritional supplements which provide nutrients and herbs to support normal heart function. That’s where Source Naturals HEART SCIENCE comes in. Two years in the making, and backed by numerous scientific studies, the nutrients in HEART SCIENCE are some of the most soundly researched of all. Combining high potencies of these super-nutrients, HEART SCIENCE is the most comprehensive, cutting edge nutritional approach to proper heart care available.

    Source Naturals HEART SCIENCE— The Five Tiered Approach to Heart Health

    Your heart never rests. Even while you sleep, your heart must keep working, relying on the constant generation of energy by the body for its very survival. If this vital organ stops beating for even a short amount of time, all bodily functions cease and life ends. Source Naturals HEART SCIENCE helps support heart function on the chemical, cellular, structural, and energetic levels. This broad spectrum formula includes ingredients specifically geared for
    1) generating energy,
    2) decreasing harmful homocysteine levels,
    3) fighting oxidized cholesterol,
    4) maintaining the heart’s electrical rhythm, and
    5) protecting artery and capillary linings.

    Energy Generators for An Energetic Organ

    Every day, the human heart beats about 104,000 times, pumping over 8,000 liters of blood through the body! Because it requires so much energy to perform efficiently, the experts at Source Naturals included specialty nutrients in HEART SCIENCE such as Coenzyme Q10 and L-Carnitine — integral factors in the body’s energy production cycles — to enhance the body’s energy supply.

    There are three main interconnected energy generating cycles in our cells — the Glycolytic (sugar-burning) cycle, the Krebs’ (citric acid) cycle, and the Electron Transport Chain. Together they supply about 90 to 95% of our body’s entire energy supply, using fats, sugars, and amino acids as fuel. Coenzyme Q10 is one of the non-vitamin nutrients needed to maximally convert food into ATP (the energy producing molecule). It is the vital connecting link for three of the four main enzyme complexes in the Electron Transport Chain, the next step in energy generation after the Krebs’ cycle. Using the raw materials generated by the Krebs’ cycle, the Electron Transport Chain produces most of the body’s total energy! The heart is one of the bodily organs which contains the highest levels of CoQ10, precisely because it needs so much energy to function efficiently.

    CoQ10 is one of the most promising nutrients for the heart under investigation today. It has been postulated that as a result of its participation in energy production, CoQ10 improves heart muscle metabolism and the electrical functioning of the heart by enhancing its pumping capacity.8 Many factors such as a high fat diet, lack of exercise, and cigarette smoking can lead to suboptimal functioning of the heart, and therefore failure of the heart to maintain adequate circulation of blood. Interestingly, people whose lifestyles reflect the above factors also tend to have depleted levels of CoQ10 in the heart muscle.10

    Researchers suggest taking between 10-100 mg per day of CoQ10;18,29 HEART SCIENCE provides an impressive 60 mg of CoQ10 per 6 tablets. Similar to CoQ10, L-Carnitine is important for energy production in heart cells. It is a natural amino acid-like substance which plays a key role in transporting fatty acids, the heart’s main source of energy, to the mitochondria, the “power plants” of each cell, where they are utilized for the production of ATP. Heart and skeletal muscles are particularly vulnerable to L-Carnitine deficiency. Studies have shown that supplementation with LCarnitine improves exercise tolerance in individuals with suboptimal heart and circulatory function, and seems to lower blood lipid status and increase HDL (good) cholesterol.16, 22 Each daily dose of HEART SCIENCE contains 500 mg of this extremely important compound.

    Like CoQ10 and L-Carnitine, B Vitamins help improve the ability of the heart muscle to function optimally. Each B Vitamin, after being converted to its active coenzyme form, acts as a catalytic “spark plug” for the body’s production of energy. Vitamin B-1, for example, is converted to Cocarboxylase, which serves as a critical link between the Glycolytic and Krebs’ Cycles, and also participates in the conversion of amino acids into energy. A deficiency of B coenzymes within contracting muscle cells can lead to a weakened pumping of the heart.21

    HEART SCIENCE is formulated with high quantities of the most absorbable forms of B Vitamins providing maximum nutrition for the high energy demands of heart cells.

    Homocysteine Regulators

    B Vitamins also play a crucial role in the conversion of homocysteine, a group of potentially harmful amino acids produced by the body, to methionine, another more beneficial amino acid. While it is normal for the body to produce some homocysteine, even a small elevation in homocysteine levels can have negative implications. It is well documented that individuals who are genetically predisposed to having elevated homocysteine levels (homocysteinemics) tend to have excessive plaque accumulation in the arteries and premature damage to endothelial cells (cells lining the blood vessels and heart).26 Researchers have found that even those without this genetic abnormality, whose homocysteine levels are much lower than those of homocysteinemics, still have an increased risk for premature endothelial damage and the development of plaque in the arteries.24, 26 One study conducted among normal men and women found that those with the highest levels of homocysteine were twice as likely to have clogged arteries as were those with the lowest levels.24 Furthermore, it was found that the lower the research subjects’ blood levels of folate and B-6, the higher their homocysteine levels.24 Another study found that Folic Acid administered to normal men and women who were not even deficient in folate caused a significant reduction in plasma concentrations of homocysteine!3 In order to regulate homocysteine levels, it is critical to provide the body with sufficient amounts of B-6, B-12, and Folate, whether through the diet or through supplementation. HEART SCIENCE includes high levels of these three nutrients, providing B-6 in the regular and coenzyme form for maximum utilization.

    The Dangers of Oxidized LDL Cholesterol

    While many people have heard that high cholesterol levels may negatively affect normal heart function, few people understand exactly what cholesterol is, or how it can become harmful. Cholesterol is a white, waxy substance produced in the liver by all animals, and used for a variety of necessary activities in the body. Your liver also manufactures two main kinds of carrier molecules which transport cholesterol throughout the system: Low Density Lipoprotein (LDL) and High Density Lipoprotein (HDL). Cholesterol is either carried out by LDL from the liver to all tissues in the body where it is deposited, or carried back by HDLs which remove cholesterol deposits from the arteries and carry them to the liver for disposal. Because of this, LDL cholesterol is considered damaging, while HDL is considered protective. Problems occur when there is too much LDL cholesterol in the body and not enough HDL.

    When the body becomes overloaded with fat, an over-abundance of LDL particles are manufactured to process it, and they in turn become elevated in the body to a degree that the liver cannot handle. Rich in fatty acids and cholesterol, these particles are highly susceptible to free radical attack (oxidation). Once oxidized, LDL particles are no longer recognized by the body, which attacks them with immune cells. Immune cells which are bloated by oxidized lipids (called foam cells) are a key factor in the development of “fatty streaks” — the first sign of excess arterial fat accumulation. The bloated immune cells accumulate in artery lesions and create plaque in blood vessels, leading to obstruction and constriction of the vessels. Plus, these lodged foam cells continue to secrete free radicals into the bloodstream, making the problem worse.

    The development of lesions in the arteries is not an uncommon problem. Arterial (and all blood vessel) walls are composed of a chemical matrix which holds the endothelial cells in place. That endothelial layer is the first and most important line of defense in preventing large molecules, such as cholesterol and fat, from entering the vessel wall. This matrix is composed of proteins, collagen, elastin, and glycosaminoglycans (amino sugars). Arterial lesions can be caused by suboptimal collagen and elastin synthesis due to three factors: 1. Vitamin C deficiency (since Vitamin C is a key building block for collagen and elastin); 2. excessive consumption of rancid fats, or heavy usage of alcohol or cigarettes; and 3. free radical damage. Once these lesions are created, the body attempts to repair them by depositing LDL cholesterol — similar to the way one would patch a tire. If that cholesterol is not oxidized, i.e. chemically changed to a harmful, unstable molecule, then this process does not create a problem. But when arterial lesions are “patched” with foam cells, arterial walls suffer page 3 page 4 even more damage, because those foam cells release free radicals which can further damage cell membranes.

    Unfortunately, most people have a lot of oxidized cholesterol floating through the bloodstream. The typical American diet, with its low antioxidant intake and overconsumption of fried and overcooked foods, contributes to the overall levels of harmful oxidized cholesterol. In fact, the average American intake of antioxidants is low even by USRDA standards, making Americans particularly prone to having high levels of oxidized cholesterol.

    Cholesterol Fighters

    Fortunately, there are concrete steps you can take to prevent the oxidation of cholesterol, and its subsequent ill effects on health. In addition to cutting out high-cholesterol and fatty foods, supplementation can protect existing cholesterol and all tissue cells — from oxidation. Antioxidants, substances which scavenge and neutralize free radicals, protect the cardiovascular system by halting the oxidation of cholesterol, and helping to prevent plaque accumulation in the arteries and the continual secretion of free radicals by foam cells. Supplementing the diet with high amounts of Vitamin C, a key antioxidant, also encourages a more healthy “patching” of existing lesions by using collagen (made from Vitamin C) instead of cholesterol. HEART SCIENCE contains generous amounts of the following antioxidants for their protective benefits:

  • • Beta Carotene, a plant pigment, is the naturally occurring precursor to Vitamin A. When the body takes in high enough amounts of Beta Carotene, this lipid-soluble free radical scavenger concentrates in circulating lipoproteins and atherosclerotic plaques, where it performs its antioxidant functions. Beta Carotene is particularly unique and powerful as an antioxidant because it is capable of trapping a very toxic form of di-oxygen, called singlet oxygen, which can result in severe tissue damage. Beta Carotene is one of the most efficient quenchers of singlet oxygen thus far discovered. Six tablets of HEART SCIENCE provide an unprecedented 45,000 IU of Beta Carotene!
  • • Vitamin C is found in plasma, the watery component of blood, where it functions as a potent antioxidant. In addition to strengthening artery linings through collagen manufacture, Vitamin C is involved in the regeneration of Vitamin E within LDL particles. Vitamin C also plays an important role in the conversion of cholesterol into bile acids by the liver, a crucial step in reducing blood cholesterol levels. Once converted into bile acids, and then into bile salts, cholesterol can be excreted from the body, preventing build-up. Supplementation with Vitamin C may lower levels of LDL cholesterol and increase those of HDL cholesterol.25 It may also have a part in actually removing cholesterol deposits from artery walls — good news for people who are already experiencing plaque buildup.25 Each daily dose of HEART SCIENCE provides 1,500 mg of Vitamin C in its bioactive mineral ascorbate form.
  • • Vitamin E, together with Beta Carotene, protects lipids from free radical attack. It is the major antioxidant vitamin that is carried in the lipid fraction of the LDL particle, where it protects the LDL particle from damaging oxidation. Within an LDL particle, one molecule of Vitamin E has the ability to protect about 200 molecules of polyunsaturated fatty acids from free radical damage! Vitamin E also aids in protecting the heart by interfering with the abnormal clumping of blood cell fragments, called platelets, within blood vessels.4 It has been shown to inhibit the formation of thromboxanes and increase the production of prostacyclins, which together decrease abnormal platelet aggregation.11 A high potency of Vitamin E — 400 IU’s — is included in six tablets of HEART SCIENCE in the natural d-alpha succinate form, recognized by scientific researchers to be the most absorbable form!
  • • Selenium is an important mineral which has only recently gained attention. When incorporated into the enzyme Glutathione Peroxidase, it has highly powerful free radical-scavenging abilities, and has been shown to work synergistically with Vitamins A, C, and E. An essential mineral, Selenium used to be derived from eating foods grown in Selenium-rich soil. However, modern agricultural practices have depleted soil of its natural Selenium content, leaving many Americans deficient in this vital nutrient. Several epidemiological studies show that the incidence of advanced fatty deposits in blood vessels is much greater in individuals living in geographic areas of the United States and other parts of the world where the Selenium content of the soil is very low.27
  • Proanthodyn,™ an extract of grape seeds, is being called the most powerful antioxidant yet discovered. This highly potent, water-soluble bioflavonoid contains between 93-95% proanthocyanidins, the highest concentration of any nutrient available today. The protective actions of proanthocyanidins may help to prevent the development of plaque in artery walls by inhibiting the free radicals which are produced during the oxidation of cholesterol. The optimal daily amount (100 mg) of Proanthodyn is included in six tablets of HEART SCIENCE. In addition to the protective actions of antioxidants, several other nutrients can contribute to healthier cholesterol ratios.
  • • Chromium is a trace mineral which functions to aid the entrance of glucose into cells. Six tablets of HEART SCIENCE provide 300 mcg of Chromium in the form of Chromate® Chromium Polynicotinate and Chromium Picolinate — the most bioactive forms of Chromium. Not many people are familiar with the vital role Copper plays in the body. This trace mineral is found in all tissues of the body, and is particularly concentrated in the heart. Copper is part of several enzymes, and, in this capacity, is necessary for the development and maintenance of the cardiovascular system, including the heart, arteries, and other blood vessels. Because of its role in elastin production, Copper deficiency can severely damage blood vessels and heart tissue. In fact, researchers have found an inverse relationship between Copper status and increased risk for heart damage.10
  • • L-Proline and L-Lysine are two natural amino acids which show exciting promise in helping to prevent fatty deposits in blood vessels. Researchers have recently identified a particle associated with LDL called apoprotein (a) which is believed to be a main culprit in plaque development. 17 Scientific investigation has revealed that the lipoprotein (a) particle has an adhesive quality that makes the lipoprotein fat globule stick inside blood vessels. The sticky fat globules accumulate, leading to fatty deposits in blood vessels and the subsequent clogging of the arteries. L-Proline and L-Lysine tend to form a barrierlike layer around the apoprotein (a) particle, helping to push it away from the blood vessel wall, and impeding deposit.21

    The Regulating Trio

    Three nutrients — Magnesium, Potassium, and Taurine — work closely together in the body to help maintain the normal electrical rhythm of the heart, promote proper fluid balance, and prevent excessive Calcium levels from building up in the heart and artery linings.

  • • Magnesium is one of the single most important nutrients for maintaining a healthy heart. It plays an extremely vital role in maintaining the electrical and physical integrity of the heart muscle. It has been well established that Magnesium deficiency predisposes humans to serious disruptions of normal cardiac rhythm. One theory is that because Magnesium has a relaxing effect on muscle tissue, inadequate Magnesium stores may make the coronary arteries more susceptible to muscle spasm.10 Too little Magnesium can cause a Calcium/Magnesium imbalance, which can lead to the influx of too much Calcium into heart cells, and potentiate spasms in heart tissue. Another point for consideration is that because it relaxes the blood vessels, Magnesium keeps these vessels open, allowing for maximum blood flow to the heart. Magnesium also has the unique ability to stop unnecessary blood clotting by helping to reduce platelet adhesion.31 Blood clots are naturally produced by the body as a protective device to stop excessive blood flow when the body is injured. The clotting response happens when the body senses that the normally smooth blood vessel linings are rough, indicating that there is a cut. However, sometimes the body mistakes the rough surface of plaque-covered arteries as cuts, and creates unnecessary blood clots. Or, if a high fat meal has just been eaten, tiny fat globules called chylomicrons enter the bloodstream and can cause platelets to become abnormally sticky, possibly creating clots. When these clots flow through the bloodstream and reach a part of the artery which has plaque buildup, normal blood flow is blocked, and the amount of blood which reaches the heart is severely compromised. Magnesium is also crucial for the entrance of Potassium — a key mineral for many bodily functions — into the cells. Even if the body’s Potassium stores are high, without enough Magnesium, the Potassium will not be able to enter the cells and be utilized by the body. 300 mg of Magnesium (75% of the U.S.RDA) are contained in each daily dose of HEART SCIENCE. Along with Magnesium, Potassium helps to regulate normal heartbeat and blood pressure, and is necessary for the contraction and relaxation of muscle tissue. Potassium and Sodium are present in all body fluids; Potassium is found primarily within cell fluids, while Sodium is usually present in fluids surrounding cells. Together, they function to maintain the normal balance and distribution of fluids throughout the body. The body ideally should have a Potassium/Sodium balance of about 1:1; however, because the body holds onto Sodium, yet eliminates Potassium quickly, it is important that the dietary ratio of these two minerals be at least 3:1. Unfortunately, the typical American diet, with its emphasis on processed, salty (Sodiumrich) foods and lack of fresh fruits and vegetables, severely alters the body’s natural Potassium/ Sodium balance. Diets in the United States are extremely high in Sodium — sometimes containing as much as 15 times the recommended daily intake! A high Sodium/low Potassium diet interferes with the normal regulation of heartbeat and blood pressure, and has been linked with elevated blood pressure.25 Taurine is an amino acid which helps normalize electrical and mechanical activity of the heart muscle by regulating Potassium flux in and out of the heart muscle cells.

    Artery Lining Protectors

    Your arteries form an integral part of your cardiovascular system, carrying blood away from the heart to nourish other parts of the body. In a healthy heart, blood surges through the arteries with every beat of the heart. The arteries expand with each pulse to accommodate the flow of blood. When arteries become hardened and narrowed by the build-up of plaque, they can’t expand and are not able to transport blood efficiently throughout the body. This inability to open up increases blood pressure, putting a strain on the heart as well as the arteries. HEART SCIENCE includes ingredients specifically geared to protect against plaque formation within arteries and maintain the flexibility of these vital blood vessels. N-Acetyl Glucosamine (NAG) is a key amino sugar which forms the building blocks of mucopolysaccharides. Mucopolysaccharides, which are long chain sugars, are an integral component of connective tissue. They combine to form gel-like matrixes which are present throughout tissues in the body, helping to maintain the elasticity of blood vessels which must continually adapt to the changing pressures of blood flow. Each daily dose of HEART SCIENCE provides 500 mg — a substantial amount — of this vital tissue building block. There is evidence indicating that Silicon, a natural mineral, may protect against plaque formation in the arteries. Silicon is found mainly in connective tissues, where it helps bind the body’s chemical matrix. Bound Silicon is found in high amounts in arterial walls. Researchers have found that there is a steady decline in the Silicon content of the aorta and other arteries as we age. This may be due to the low fiber content of the typical American diet, since fiber is a key dietary source of Silicon.23 HEART SCIENCE includes 400 mg of Horsetail herb extract, a natural source of Silicon. Hawthorn Berry is without question the herb most widely used to encourage normal heart function. The beneficial actions of Hawthorn Berry on cardiac function have been repeatedly demonstrated in experimental studies. Supplementation with Hawthorn Berry has been shown to improve both the blood supply to the heart by dilating coronary vessels, and the metabolic processes in the heart, resulting in normal, strong contractions of the heart muscle.34 Also, Hawthorn may inhibit the angiotensen converting enzyme, which is responsible for converting angiotensen I to angiotensen II, a powerful constrictor of blood vessels.34 Bromelain, a natural enzyme derived from pineapples, has become well-known for its neuromuscular relaxing properties. Researchers have reported favorable results when using Bromelain for soothing vascular linings. Initial research also indicates that Bromelain may break down fibrin, the glue which holds platelets together to form blood clots.6

    Capillary Strengtheners

    Capillaries are the smallest, yet some of the most important, blood vessels. If you think of your cardiovascular system as a series of roads which transport blood and oxygen, then your arteries are akin to interstate highways, your arterioles are the main city boulevards, and your capillaries are local residential streets. Capillaries are so small, in fact, that single red blood cells actually have to fold up to fit through them. Because of their tiny size and the intricate nature of their network throughout the body, capillaries are responsible for actually nourishing each individual tissue cell! Along the length of the capillaries are small openings called slit pores through which oxygen, glucose, and nutrients leave the capillaries and enter the surrounding interstitial fluid. From there, they cross cell membranes and nourish the cells. Similarly, the waste products of cells enter the fluid and cross over into the capillaries, where they are then transported to the liver and kidneys for disposal. If the capillary slit pores are torn or have lesions, then blood proteins and Sodium will leak out and cause the interstitial fluid to take on a more gel-like nature. This makes the transfer of oxygen and nutrients to the cells more difficult, as well as the disposal of cell waste products, turning the fluid into a stagnant swamp instead of a flowing river. In addition to its powerful antioxidant actions, Proanthodyn also helps protect collagen and elastin, the main constituents of tissue in the capillaries, and throughout the body. It is absolutely essential for capillary walls — which are only one cell thick — to be strong and stable, so that they do not allow blood proteins to leak into the interstitial fluid. Once the interstitial fluid takes on a gel-like consistency, the surrounding cells literally become starved from lack of nutrition. The exciting news is that the proanthocyanidins contained in Proanthodyn are among the few substances yet discovered which can help strengthen capillary walls, ensuring the liquid nature of the interstitial fluid.2 Plus, proanthocyanidins help keep capillary and artery walls flexible, allowing for proper blood flow to the heart.

    Heart Smarts

    The 1990’s mark a decade of increased awareness among Americans of important health issues. Much of the discussion has revolved around protecting that precious center of life we call the heart. Simple lifestyle change is one of the most effective ways to maintain and protect the functioning of the cardiovascular system. In order to take a holistic approach to heart care, make sure you include plenty of fresh fruits and vegetables (organic, if possible) in your diet, and cut down on fatty and cholesterol-forming foods. Reduce your salt and alcohol intake to a minimum. Try to get regular, sustained aerobic exercise for at least 30 minutes three times a week. Don’t smoke – or if you do smoke, try to eat even more fresh fruits and antioxidant-rich vegetables to counter the amount of free radicals being produced in your body. Lastly, consider adding Source Naturals HEART SCIENCE to your health regimen. HEART SCIENCE, the most comprehensive formula of its kind, provides targeted protection to the entire cardiovascular system. By approaching the promotion of normal heart function on five different levels — through the inclusion of ingredients which supply energy, decrease harmful homocysteine levels, fight cholesterol build-up, help regulate electrical rhythm, and protect artery and capillary linings — HEART SCIENCE is the perfect addition to a holistic approach to heart care.

    Source Naturals HEART SCIENCE™


    The Five Tiered Approach to Heart Health
    Six tablets contain:
    Vitamins and Minerals %USRDA
    Pro-Vit A (Beta Carotene) 45,000 IU 900%
    Vit B1 (Thiamine) 50 mg 3333%
    Vit B3 (Inositol Hexanicotinate) 500 mg 2500%
    Vit B6 (Pyridoxine HCl) 25 mg 1250%
    Coenzyme B6 (Pyridoxal-5-Phosphate)
    25 mg yielding: 16.9 mg of Vit B6 845% (Total Vitamin B6 Activity) (41.9 mg) (2095%)
    Vit B12 (Cyanocobalamin) 500 mcg 8333%
    Folic Acid 800 mcg 200%
    Vit C (Magnesium Ascorbate) 1500 mg 2500%
    Vit E (d-alpha Tocopheryl Succinate) 400 IU 1333%
    Chromium (ChromeMate® †Polynicotinate-150 mcg & Chromium Picolinate††-150 mcg) 300 mcg *
    Copper (Sebacate) 750 mcg 37.5%
    Magnesium (Ascorbate, Taurinate & Oxide) 300 mg 75%
    Potassium (Citrate) 99 mg *
    Selenium (L-Selenomethionine) 200 mcg *
    Silicon (From 400 mg of Horsetail Extract) 13mg *
    * U.S. RDA not established.
    Other Ingredients and Herbs
    Coenzyme Q10 (Ubiquinone) 60 mg
    L-Carnitine (L-Tartrate) 500 mg
    Hawthorn Berry Extract 400 mg
    Proanthodyn™ (Yielding 95 mg of Proanthocyanidins from grape seed extract) 100 mg
    L-Proline 500 mg
    L-Lysine (HCl) 500 mg
    NAG™ (N-Acetyl Glucosamine) 500 mg
    Bromelain (2000 G.D.U. per gram) 1200 G.D.U.
    Taurine (Magnesium Taurinate) 500 mg
    Horsetail Extract (Yielding 31 mg of Silica) 400 mg
    Inositol (Hexanicotinate) 50 mg

    Reference:
    1. Azuma, J., Sawamura, A., & Awata, N. (1992, Jan). “Usefulness of Taurine... and its Prospective Application.” Japanese Circulation Journal, 56(1), 95-9.
    2. Blazso, G and Gabor, M. (1980). “Odema-inhibiting Effect of Procyanidin.” Acta Physiologica Academiae ScientiarumHungaricae, 56(2), 235-240.
    3. Brattstrom, E. L, Hultberg, L. B., & Hardebo, E. J. (1985, Nov.). “Folic Acid Responsive Postmenopausal Homocysteinemia.” Metabolism, (34)11, 1073-1077.
    4. Colette, C., et al., (1988). “Platelet Function in Type I Diabetes: Effects of Supplementation with Large Doses of Vitamin E.” American Journal of Clinical Nutrition, 47, 256-61.
    5. England, M. R., et al. (1992, Nov. 4). “Magnesium Administration and Dysrhythmias...A Placebo-controlled, Double-blind, Randomized Trial.” Journal of the American Medical Association, 268(17), 2395-402.
    6. Felton, G. E. (1980, Nov.). “Fibrinolytic and Antithrombotic Action of Bromelain...” Medical Hypotheses (11)6, 1123-33.
    7. Grundy, S. M. (1993, Apr.). “Oxidized LDL and Atherogenesis: Relation to Risk Factors...” Clinical Cardiology, 16 (4 Suppl.I), I3-5.
    8. Hano, O. et al. (1994, June). “Coenzyme Q10 Enhances Cardiac Functional and Metabolic Recovery and Reduces Ca2+ Overload during Postischemic Reperfusion.” American Journal of Physiology, 266(6 Pt 2), H2174-81.
    9. Heineke, et al. (1972). “Effect of Bromelain (Ananase) on Human Platelet Aggregation.” Experientia V. 23, 844-45.
    10. Hendler, S. S. (1991). The Doctors’ Vitamin and Mineral Encyclopedia. NewYork: Fireside.
    11. Jandak, et al. (1988, Dec. 15). “Reduction of Platelet Adhesiveness by Vitamin E Supplementation in Humans.” Thrombosis Research 49(4), 393-404.
    12. Jialal, I., et al. (1991, Oct. 15). “Beta-Carotene Inhibits the Oxidative Modification of Low-density Lipoprotein.” Biochimica et Biophysica Acta, 1086(1), 134-8.
    13. Jialal, I. & Fuller, C. J. (1993, Apr. 16). “Oxidized LDL and Antioxidants.” Clinical Cardiology, Vol. 16 (Suppl. I), I6-9.
    14. Jialal, I., & Grundy, S.M. (1991, Feb.). “Preservation of the Endogenous Antioxidants in Low Density Lipoprotein...” Journal of Clinical Investigation, 87(2), 597-601.
    15. Kamikawa, T., et al. (1985). “Effects of Coenzyme Q10 on Exercise Tolerance...” American Journal of Cardiology, 56, 247-251.
    16. Kosolcharoen, P., et al. (1981, Nov.). “Improved Exercise Tolerance after Administration of Carnitine.” Current Therapeutic Research, 753-764.
    17. Lawn, R. (1992, June). “Lipoprotein (a) in ...” Medicine, 12-18.
    18. Mortensen, S.A.et al. (1985). “Long-term coenzyme Q10 therapy: A major advance in the management of resistant myocardial failure.” Drugs Exp. Clin. Res., 11(8), 581-93.
    19. Nayler, W. G. (1980). “The Use of Coenzyme Q10 to Protect Ischemic Heart Muscle.” In: Yamamura Y., Folkners K., Ito Y., eds. Biomedical and Clinical Aspects of Coenzyme Q, Vol. 2, Amsterdam: Elsevier/North-Holland Biochemical Press, 409-425.
    20. Press, R.I., & Geller, J., (1990, Jan.). “The Effect of Chromium Picolinate on Serum Cholesterol and Apolipoprotein Fractions in Human Subjects.” Western Journal of Medicine, 152, 41-45.
    21. Rath, M. (1993). Eradicating Heart Disease. San Francisco: Health Now.
    22. Rossi, C. S., & Silliprandi, N. (1982, Feb.). “Effect of Carnitine on Serum HDL Cholesterol: Report of Two Cases.” Johns Hopkins Medical Journal, 150(2), 51-4.
    23. Schwarz, K. (1977, Feb. 2). “Silicon, Fibre, and Atherosclerosis.” The Lancet, 454-456.
    24. Selhub, J., et al. (1995, Feb. 2). “Association Between Plasma Homocysteine Concentrations and Extracranial Carotid-artery Stenosis.” New England Journal of Medicine, 332(5), 286-291.
    25. Somer, Elizabeth. (1992). The Essential Guide to Vitamins and Minerals. New York: Health Media of America.
    26. Stampfer, M. J., et al. (1992, Aug. 19). “A Prospective Study of Plasma Homocyst(e)ine...” Journal of the American Medical Association, 268(7), 877-881.
    27. Suadicani, P., Hein, H. O., & Gyntelberg, F. (1992, Sept.). “Serum Selenium Concentration...in a Prospective Cohort Study of 3000 Males.” Atherosclerosis, 96(1), 33-42.
    28. Thomas, C. L. (Eds.). (1985). Taber’s Cyclopedic Medical Dictionary, (15th ed.). Philadelphia: F.A. Davis Company.
    29. Tsuyusaki, T. et al. “Mechanocardiography of ischemic or hypertensive heart failure,” in Yamaura Y et al., Biomed. & Clin. Aspects of Coenzyme Q.2 Amsterdam, Elsevier/North Holland Biomedical Press, 1980, 273-88.
    30. Verlangieri, A. J., & Stevens, J. W. (1979). “L-Ascorbic Acid: Effects on Aortic Glycosaminoglycan S Incorporation...” Blood Vessels, 16(4), 177-185.
    31. Werbach, M. R. (1987). Nutritional Influences on Illness: A Sourcebook of Clinical Research. New Canaan: Keats Publishing, Inc.
    32. White, R.R., et al. (1988, Jul-Aug.). “Bioavailability of 125I Bromelain after Oral Administration to Rats.” Biopharmaceutics and Drug Disposition, 9(4), 397-403.
    33. Whitney, E. N., Hamilton, Nunnelly, E. M. (1984). Understanding Nutrition, (3rd ed.). St. Paul: West Publishing Company.
    34. Willard, Terry, Ph.D. (1992). Textbook of Advanced Herbology. Calgary, Alberta, Canada: Wild Rose College of Natural Healing.
    35. Xiang, H., Heyliger, et al. (1988, Nov.). “Effect of Myo-inositol and T3 on Myocardial Lipids and Cardiac Function in Streptozocin-induced Diabetic Rats.” Diabetes, 37(11), 1542-8.



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    GlucosaMend™ Tissue/Joint Repair Complex
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    Date: June 02, 2005 11:19 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: GlucosaMend™ Tissue/Joint Repair Complex

    GlucosaMend

    More than 40 million Americans experience joint discomfort. But exciting new research proves you can do something about it. Our health and well-being is inextricably linked to lifestyle choices: the right combination of exercise, weight training and supplementation can strengthen muscles and joint tissues to minimize stress and degradation. Targeted nutrition to the multiple body systems related to joint and connective tissue can help maintain flexibility and joint comfort. GLUCOSAMEND supports the musculoskeletal system with structural building blocks and tissue production cofactors, as well as aiding the body’s mechanisms for soothing relief and antioxidant defense.

    Bio-Aligned Formula™ GLUCOSAMEND is uniquely effective because it is a Bio-Aligned Formula. Source Naturals evaluates the underlying causes of system imbalances. Then we design formulas that provide targeted nutrition to bring your interrelated body systems back into balance.

    Musculoskeletal System—Structural Building Blocks

    Certain building blocks of joints and connective tissue can help maintain joint integrity and comfort. Glucosamine is a major constituent of glycosaminoglycans, which in turn form proteoglycans, molecules that hold and bind the water that lubricates joints, disperses stress and nourishes joint tissue. The amino acids proline and lysine are structural components of collagen and elastin, which give strength to connective tissue. GLUCOSAMEND contains glucosamine sulfate, N-acetyl glucosamine, proline and lysine.

    Musculoskeletal System—Tissue Production Cofactors

    Some micronutrients are necessary as cofactors in the production of connective tissue. For example, vitamin C and copper help form hydroxyproline and hydroxylysine, main constituents of collagen. A unique property of grape seed extract is its ability to form a bond between broken collagen fibers, helping to repair them and restore flexibility and strength to connective tissues and joints. GLUCOSAMEND provides vitamin C, zinc, manganese, copper, and grape seed extract to address these cofactors.

    Soothing Relief Mechanisms

    Some herbs and nutrients have the capacity to support the body’s natural mechanisms for increasing comfort. Boswellia, for example, is an herb with soothing properties, while vitamin B-6 helps to stabilize collagen and elastin. Additional herbs and nutrients, acting in conjunction with antioxidant Protectors, support tissue comfort and health. GLUCOSAMEND contains Boswellia serrata, quercetin, copper, and vitamin B-6.

    Antioxidant Defense

    The health and integrity of joints and tissues—specifically of cell membranes— is supported by botanicals and nutrients that support the body’s natural antioxidant response. When tissues become damaged, the body mounts a repair process that ultimately generates free radicals. These free radicals can also break down healthy cells and tissues in the process, hence the need for antioxidants to neutralize and break the cycle. GLUCOSAMEND provides grape seed extract, vitamin C, zinc, selenium, copper, quercetin to neutralize free radicals.

    Lifestyle Tips for Healthy Joints: A Strategy for WellnessSM

    Healthy lifestyle habits should be part of your individual strategy for joint wellness. Source Naturals believes in a holistic approach to living. Not only can supplements bring balances to your individual body systems but certain lifestyle choices can also bio-align your health. Exercise Regularly: Regular physical activity helps lubricate cartilage, strengthens muscles around joints, and promotes weight control. An exercise program geared to joint health includes stretching, mild weight training, and low-impact aerobics. Watch Your Weight: Population-based studies, including the well-known Framingham study, have consistently shown a link between obesity and challenges to joint health. Excess weight causes pressure on joints, and can speed the rate at which cartilage wears down. Eat Healthy: To support healthy joints, increase your intake of omega-3 fatty acids from salmon, sardines, flax seeds or flax oil, avoid excess protein intake, and replace animal with plant proteins when possible. You should also eat lots of organically grown fruits and vegetables, limit saturated fat and eliminate hydrogenated oils. Rest and Relaxation: Regularly scheduled rest gives your body time to recover and rebuild, allowing you to make the most of your exercise program. It’s important to know when to slow down. Supplementation: Source Naturals offers a range of products that can supplement your strategy for joint wellness. These include the pineapple enzyme BROMELAIN; SAME, a natural compound formed from the amino acid methionine, which has been found to support joint comfort and mobility; and CHONDROITIN to promote water retention and elasticity in cartilage and inhibit enzymes that break down cartilage.

    Structural Building Blocks N-Acetyl Glucosamine, Glucosamine Sulfate, L-Lysine, L-Proline Tissue Production Cofactors Grape Seed, Copper, Manganese, Zinc, Vitamins A, B-6 and C, Niacinamide Soothing Relief Mechanisms Boswellia Serrata, Quercetin, Turmeric, Copper, Magnesium, Zinc, Vitamin C Antioxidant Defense Grape Seed, Quercetin, Manganese, Selenium, Zinc, Vitamins A, C and E

    References
    Bhavan’s, B. H. Selected Medicinal Plants of India (A Monograph of Identity, Safety, and Clinical Usage) Bombay: Chemexcil, 1992. Dore-Duffy, P., et al. (1990, Nov-Dec.). “Zinc profiles...” Clinical and Experimental Rheumatology 8.6: 541-46. Ellis, J. M. (1985, Winter). “Vitamin B6 deficiency and rheumatism.” Anabolism. Lakshmi, R., et al. (1991, Oct-Dec.). “Effect of riboflavin or pyridoxine deficiency on inflammatory response.” Indian Journal of Biochemistry and Biophysics 28.5-6: 481-84. Leibovitz, B., (1991). Nutrition Update 5.3: 5. Levine, M. (1986). “New concepts in the biology and biochemistry of ascorbic acid.” New England Journal of Medicine 314: 892-902. Pavelka, K, Gatterova, J., Olejarova, M, Machacek, S., Giacovelli, G., Rovati, L.C., (2002). “Glucosamine Sulfate Use and Delay of Progression of Knee Osteoarthritis: A 3-Year, Randomized, Placebo-Controlled, Double-Blind Study. Arch Intern Med, 2002 October 14; 162(18):2113-23. Roubenoff, R., et al. (1995, Jan.). “Abnormal vitamin B6 status...” Arthritis and Rheumatism 38.1: 105-9. Shampe, P., and R. Harvey. Lippincotts Illustrated Reviews: Biochemistry. Philadelphia: J. B. Lippincott Company, 1987. Tarp, U., et al. (1985). Scandanavian Journal of Rheumatology 14.2: 97-101. Volpi, N., (2002). “Oral bioavailability of chondroitin sulfate (Condrosulf) and its constituents in healthy male volunteers,” 2002 Oct; 10(10):768.



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    COENZYME Q10 - Transforming food into energy
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    Date: June 01, 2005 11:06 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: COENZYME Q10 - Transforming food into energy

    Coenzyme Q10

    It’s 3:30 p.m. and you feel irritable; you can’t seem to concentrate. You were so busy you skipped lunch. At last you bite into the sandwich that you were ready for 3 hours ago. By the time you have eaten half of it, energy is starting to flow through you. What happened? The answer to that question is both extremely complex and very simple. In essence, your body transformed the food into useable energy. CoQ10 is a crucial component of the primary energy generating cycle that takes place in each of the trillions of cells in our bodies. CoQ10 is essential for human life.

    To transform that lunchtime sandwich into useable energy your body essentially has to burn it - just the way a car burns gasoline to drive its engine. This energy generating process takes place in structures called mitochondria - tiny power plants which are within every cell. Inside these energy generating stations, fats, sugars, and amino acids are transformed into ATP, an energy-rich molecule sometimes called the “energy currency” of the body.

    Energy Generation Requires Nutrients

    The body requires many nutrients in order to perform the complex biochemical processes that convert food into ATP “energy currency.” Some of these nutrients such as the B-vitamins are familiar to us. However, there are many other substances which are essential to this process. Coenzyme Q10 is one of these.

    Functions of CoQ10

    Several complex metabolic pathways are required in order for the body to transform that lunchtime sandwich into energy that you can feel and use. First glycolysis and the Krebs’ cycle break down large molecules of protein, carbohydrate and fat into smaller components. CoQ10 is a key enzyme in the Electron Transport Chain - the final stage in this extraordinary design. This pathway generates 90% of the ATP needed by the body from the food we eat. ATP provides the “energy currency” for the following crucial metabolic functions: 1) synthesis of cellular components including cholesterol and proteins (formed primarily by the liver), 2) nerve conduction (in the brain and peripheral nerves), and 3) energy for muscular contraction (of the heart and skeletal muscles). The Heart: The heart muscle (myocardium) consumes a tremendous amount of energy. Your heart beats over 100,000 times and pumps 1,000 gallons of blood each day! CoQ10 is necessary for the generation of the energy required by the heart. Numerous scientific studies have demonstrated that supplementation with this nutrient may support normal heart function. Its presence is necessary for cardiac performance during exercise as exemplified by criteria including: blood flow, oxygen utilization, contractility and exercise tolerance. In addition, CoQ10 may play a role in the regulation of blood pressure. The Gums: Since the 1970’s scientists have been researching the effects of CoQ10 on the health of the oral tissues. Although the mechanism of action is not known, research has established that CoQ10 has a profound ability to preserve and maintain the health of the gums. Antioxidant Properties: CoQ10 plays an additional vital role in our metabolism as a Protector of lipids in cell membranes. Laboratory studies have also shown that CoQ10 is more efficient than vitamin E, beta carotene or lycopene in safeguarding LDL cholesterol from oxidation by peroxides. This process is important for maintaining the health of our blood vessels.

    Energy Insurance

    CoQ10 is needed in body tissues where energy production is critical, such as the liver, brain and muscles. Therefore we include CoQ10 in significant potencies in many of our premium formulas, such as Life Force Multiple™, Élan Vitàl™, Heart Science™, Liver Guard™, MenoBalance™, Higher Mind™, MegaMind™ and Wellness Multiple™. We also offer a combination of CoQ10 and Lipoic Acid (30 mg each), CoQ10 Sublingual (30 mg and 60 mg), 30 mg CoQ10 Softgels with Bioperine® and 30 mg CoQ10 NutraSpray™. Our single CoQ10 products are CoQ10 in 15 mg, 30 mg, 75 mg, 100 mg, and Ultra Potency 125 mg caps.

    References
    1) Folkers et al., BCACQ, Elsevier, 1977
    2) Judy et al., BCACQ, Elsevier, 1984.
    3) Kamikawa, T. et al., American Journal of Cardiology, Vol. 56, August 1, 1985, p. 247-250.
    4) Nohara et al., Biomedical and Clinical Aspects of Coenzyme Q, Elsevier, 1984.
    5) Packer, L., Oxidative Stress and Aging, Birkhauser Verlad, 1995.
    6) Stocker, et al., Proceedings of the National Academy of Sciences, Vol. 88, pp 1646-1650, March 1991.
    7) Tortora, G. Principles of Human Anatomy, 4th Ed., Harper & Row, New York, 1986, p. 301.
    8) Wilkinson and Arnold, Biomedical and Clinical Aspects of Coenzyme Q, Elsevier, 1977.
    9) Yamagami et al., Biomedical and Clinical Aspects of Coenzyme Q, Elsevier, 1977.



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    Cholestrex - Lower Cholesterol with Source Naturals Supplements
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    Date: June 01, 2005 10:41 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Cholestrex - Lower Cholesterol with Source Naturals Supplements

    Cholestrex

    Our lives depend on an uninterrupted flow of blood throughout the 60,000 miles of arteries, veins, and capillaries that bring vital nourishment to our cells. Our bodies have complex chemical strategies to maintain and repair blood vessel walls. Cholesterol is an important part of the process. However, too much cholesterol in the bloodstream can have serious consequences for our well-being. By understanding how nutrition affects blood cholesterol, we can gain valuable control of our health. Source Naturals CHOLESTREX has been formulated to provide the nutritional support that we need to maintain healthy cholesterol levels.

    SINCE DOCTORS FIRST DISCOVERED that cholesterol was the primary ingredient in the sticky deposits that clogged their patients’ arteries, scientists have gained a thorough understanding of cholesterol’s role in our health. Essential to human and animal life, cholesterol is part of every cell in the body. Because cholesterol is so important, the liver synthesizes from 1 to 2 grams of it each day. In addition, we get about another 500 mg from the foods we eat. Problems occur when too much cholesterol gets into the bloodstream. Today, it’s estimated that over 50 million adults in the United States have cholesterol levels that are too high. The body’s processes to manage excess cholesterol depend upon a lifestyle that includes exercise, stress reduction and proper nutrition. Source Naturals Cholestrex is designed to deliver a comprehensive combination of nutrients known to support a healthy blood vessel system – and keep the life stream flowing.

    The nutrients in CHOLESTREX are known to support a healthy blood vessel system

    Cholesterol: What It Is Cholesterol is a solid waxy substance, technically classed as a “sterol.” Cholesterol enables our cell membranes to maintain their integrity. It is the basic raw material from which the body makes steroid hormones, which include the sex hormones. Cholesterol is the primary component of bile salts that the liver creates to help us assimilate fats, fat-soluble vitamins and essential fatty acids. The liver also uses bile to rid itself of stored toxins. Our skin contains large amounts of cholesterol, making it resistant to the absorption of water-soluble toxins. Even the brain is 7% cholesterol (dry weight).

    Blood vessel walls cover a surface area of half an acre and are under constant pressure

    Cholesterol in the Blood

    Because it’s not water-soluble, cholesterol must be attached to a carrier molecule in order to be transported in the bloodstream. The liver manufactures two types of carrier molecules for cholesterol, LDL and HDL. LDL (low density lipoprotein) molecules carry cholesterol from the liver out to cells of the body. One of its functions is to repair damaged cells, including those of the artery walls. LDL is primarily made up of saturated fats, (meat fats, butter, etc.). HDL (high density lipoprotein) molecules transport cholesterol and fatty acids from body tissues back to the liver for disposal. HDL helps remove excess fat and cholesterol from the bloodstream. HDL is composed of liquid fats (most vegetable oils). It’s crucial to have a proper balance between LDL and HDL cholesterol. High LDL – a sign that the body has too much fat – is a threat to the health of blood vessels, because excess LDL cholesterol may accumulate in damaged areas of vessel walls. These “fatty streaks” are the beginning stage of artery blockage.

    The oxidation of LDL cholestrol is at the heart of the problem

    Cholesterol and Artery Damage

    The walls of the blood vessels cover a surface area of half an acre and are under constant pressure. Of all the blood vessels in the body, the coronary arteries are under the greatest stress. Named for the Latin word for crown (corona), they sit directly on the heart muscle and must continually expand and contract with every heartbeat. That’s 100,000 times each day. This constant squeezing can cause small lesions in the artery wall. This triggers a repair process where LDL cholesterol comes in to patch up the damage. Recent research has found that the crux of the problem is the oxidation of LDL cholesterol. Rich in fatty acids, the LDL molecule becomes permanently altered when oxidized by free radicals (overreactive molecules that steal electrons from other molecules). These rancid, oxidized LDL molecules are no longer recognized by the body, so they’re attacked by immune system cells. These immune cells become bloated with the oxidized lipids, accumulate in artery lesions and create plaque in blood vessels. Why is LDL cholesterol being oxidized? First of all, there’s too much of it in the blood, while not enough HDL. Secondly, the blood doesn’t have enough antioxidants to neutralize free radicals. The ingredients in Source Naturals Cholestrex address these specific problems in several ways. Cholestrex also provides nutrients that protect and strengthen blood vessel walls.

    In the typical American diet, 95% of the cholesterol meant for removal is reabsorbed

    Cholestrex Has It All

    Vitamin C helps maintain the health of artery walls because it’s the key building block for collagen and elastin, the primary constituents of blood vessels. Copper is required by the enzyme that weaves together the fibers of collagen and elastin into the matrix that makes vessel walls both tough and flexible. As an antioxidant, vitamin C scavenges free radicals in the blood plasma and also regenerates vitamin E within the LDL molecule. Vitamin E has a critical role as the primary Protector of LDL, preventing its oxidation. One molecule of vitamin E can protect 200 molecules of polyunsaturated fatty acids from free radical damage. GTF Chromium is involved in insulin activity and the normalization of blood sugar. Excess simple sugars are converted to triglycerides, the blood fats which can accumulate in artery walls. Lecithin is a component of HDL that emulsifies excess blood fat so it can be more readily transported in the bloodstream to the liver, where it’s metabolized. Vitamin B3 (niacin) assists in the metabolism of fats, and puts an electric charge on red blood cells so they repel each other, which prevents blood clumping. The amino acid, L-Arginine, works to lower serum cholesterol and triglycerides by inhibiting fat absorption.

    Beta sitosterol neutralizes incoming dietary cholesterol

    The Body’s Cholesterol Removal System

    HDL molecules carry cholesterol from tissues throughout the body back to the liver, where it is incorporated into bile salts. These bile salts are sent to the intestines, where they combine with fiber for excretion. One problem with the typical American low fiber diet is that 95% of the bile-bound cholesterol is reabsorbed. Since this is the body’s primary pathway for ridding itself of excess cholesterol, another strategy incorporated into Cholestrex is to maximize the production of bile salts and minimize their reabsorption by increasing levels of fiber. Fiber is a key element of Cholestrex. Its four types of soluble fiber bind with bile salts that are laden with cholesterol to ensure their excretion from the body. Oat Bran & Fiber, Grapefruit Pectin, Psyllium Seed Husks and Alfalfa Seeds also absorb cholesterol from our food, thereby lowering total blood cholesterol. Alfalfa seeds are considered a blood purifier. Beta sitosterol, a plant equivalent of cholesterol, binds to sites in the intestines that would otherwise absorb cholesterol. Cholestrex provides a daily total of 300 mg of beta sitosterol which may, by itself, neutralize 200 to 300 mg of incoming dietary cholesterol by preventing its absorption. Vitamin C, among its many other vital roles, is the key factor in activating an enzyme that will increase the liver’s conversion of cholesterol into bile salts. CHOLESTREX uses bioactive mineral ascorbate forms of vitamin C that will not irritate the digestive system. Working in conjunction with the fiber in CHOLESTREX, Calcium increases HDL, while lowering total serum cholesterol.

    Cholestrex–Intelligent Nutritional Support

    Our generation is fortunate to witness the remarkable progress made by modern science in understanding the body’s complex biochemical processes. As we realize the vital connection between nutrition and cholesterol levels, we are empowered to improve our health and vitality beyond previous standards of wellness. Source Naturals CHOLESTREX. For you and the ones you love.

    Reference:
    1. Drexel, H., et al. “Lowering Plasma Cholesterol with Beta Sitosterol and Diet.” The Lancet 1 (1981): 157.
    2. Grundy, S. M., et al. “Influence of Nicotinic Acid on Metabolism of Cholesterol and Triglycerides in Man.” Journal of Lipid Research 22 (1981): 24-36.
    3. Grundy, S. M. “Oxidized LDL and Atherogenesis: Relation to Risk Factors...” Clinical Cardiology Vol. 16 (Suppl. I), April 1993: 13-15.
    4. Hendler, S. S. “The Doctors’ Vitamin and Mineral Encyclopedia.” New York: Fireside, 1991.
    5 Jialal, I., and C. J. Fuller. “Oxidized LDL and Antioxidants.” Clinical Cardiology Vol. 16 (Suppl. I), April 1993: 16-19.
    6. Kay, R. M. and A. S. Truswell. “Effect of Citrus Pectin on Blood Lipids and Fecal Steroid Excretion.” American Journal of Clinical Nutrition 30.2 (1977): 171-75.
    7. Kirby, R. W., et al. “Oat Bran Intake Selectively Lowers Serum Low Density Lipoprotein Cholesterol Concentrations of Hypercholesterolemic Men.” American Journal of Clinical Nutrition 34.5 (1981): 824-29.
    8. Malinow, M. R., et al. “Alfalfa.” American Journal of Clinical Nutrition 1979: 1810-12.
    9. Mattson, Fred H., Scott M. Grundy, and John R. Crouse. “Optimizing the Effect of Plant Sterols on Cholesterol Absorption in Man” The American Journal of Clinical Nutrition 35 (April 1982): 697-700.
    10. Railes, R. and M. J. Albrink. “Effect of Chromium Chloride Supplementation on . . . Serum Lipids Including High Density Lipoprotein of Adult Men.” American Journal of Clinical Nutrition 34 (1981): 2670-78.
    11. Turley, S. D. and J. M. Dietschy. “The Metabolism and Excretion of Cholesterol by the Liver.” in The Liver: Biology and Pathobiology, I.M. Arias, et al. Raven Press, 1988.
    12. Turley, S. D., et al. “Role of Ascorbic Acid in the Regulation of Cholesterol Metabolism and the Pathogenesis of Atherosclerosis.” Atherosclerosis 24 (1976): 1-18.



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    Bioflavonoid Complex - Botanical Antioxidant Protection
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    Date: June 01, 2005 09:15 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Bioflavonoid Complex - Botanical Antioxidant Protection

    Bioflavonoid Complex

    The plant kingdom offers some of nature's most powerful antioxidants— biological molecules that scavenge and neutralize damaging free radicals. Source Naturals BIOFLAVONOID COMPLAEX ™ features outstanding plant antioxidants in a potent defense complex. Often referred to as "specialty bioflavonoids," these premium botanical Protectors may have an affinity for specific organs and body systems. BIOFLAVONOID COMPLEX contains botanicals that support cardiovascular function, circulation, joint and connective tissue, vision, the liver, and the brain and nervous system.

    Specialty Bioflavonoids

    Bioflavonoids occur as pigments in plants, where they are found in close association with vitamin C. Together, bioflavonoids and C provide antioxidant protection, helping plants withstand harsh environmental conditions. BIOFLAVONOID COMPLEX features potent botanical extracts, many of them standardized to specific beneficial constituents. Included are bilberry, ginkgo biloba, grape seed, green tea, hawthorn berry, quercetin, and silymarin. The formula is enhanced by the addition of vitamin C as highly bioavailable magnesium ascorbate.

  • Grape Seed Extract (Proanthodyn ™): Grape seed is rich in proanthocyanidins, a special class of antioxidants that are soluble in both water and fat. Proanthocyanidins have been shown in in vitro studies to support the integrity of elastin and collagen, important constituents of joint and connective tissue.
  • Green Tea: Green tea extract is a rich source of polyphenols, particularly (-)epigallocatechin gallate (EGCG). EGCG has been found in scientific studies to be a potent antioxidant.
  • Quercetin: Quercetin is a unique non-allergenic bioflavonoid present in some foods, such as onions. Human cell culture studies with quercetin have demonstrated its capability to inhibit the release of histamine from mast cells.
  • Ginkgo biloba: Ginkgo, the subject of extensive research, is espe- cially renowned for its ability to promote blood flow to the brain. BIOFLAVONOID COMPLEX features Ginkgo-24™, a standardized concentration of prime quality ginkgo leaves, yielding 24% ginkgo flavone glycosides and 6% terpenes (the key constituents) from a 50-to-1 concentration.
  • Bilberry: BIOFLAVONOID COMPLEX contains a potent standardized extract of bilberry that contains 37% anthocyanosides. Anthocyanosides have demonstrated significant antioxidant activity, according to in vitro studies. Bilberry has been a staple of European herbal therapy for centuries, and is widely used for supporting normal vision.
  • Silymarin: Silymarin is the name given to a complex of three compounds—silybum, silycristin, and silymarin— extracted from milk thistle seeds. Silymarin has demonstrated antioxidant activity and the ability to inhibit lipid peroxidation of cell membranes, according to in vitro studies. Silymarin has a special affinity for the liver, which is vital for digestion, detoxification, blood sugar regulation and fat metabolism.
  • Hawthorn: Hawthorn berries are a highly concentrated source of anthocyanidins and proanthocyanidins. In addition to their roles as free radical scavengers, these flavonoids increase intracellular vitamin C levels and decrease capillary permeability and fragility. Hawthorn is renowned for cardiovascular support.
  • Vitamin C: Bioflavonoids are most effective in the presence of vitamin C, the nutrient they are most often paired with in nature. The C in BIOFLAVONOID COMPLEX is bound to the mineral magnesium, a process which minimizes acidity and increases the bioavailability of both nutrients.
  • References
    Armstrong, D., et al. (1984). Free Radicals in Molecular Biology, Aging, and Disease. Raven Press: NY Braquet, P. ed. (1988). Ginkgolides: Chemistry, Biology, Pharmacology, and Clinical Perspectives. J.R. Prous Science Pub: France. Busse, W.W., et al. (1984). J Aller and Clinic Immunol, 73:801-809. Hikino, et al. (1984). Planta Medica 50: 248-50. Meunier, M.T. et al. (1989). Plantes Med et Phytother, 23(4):267-274. Packer L. (1994) Ann. N.Y. Acad. Sci. 738: 257-264. Schmidt, U. et al. (1994). Phytomed 1: 17-24.



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