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	Chondroitin Sulfate - The Joint Health Superstar You May Not Know About	Darrell Miller	9/29/22
	Shark Cartilage and Its Benefit in Improving Joint Health	Darrell Miller	10/29/13
	Natural Remedies for Arthritis	Darrell Miller	2/8/12
	GLUCOSAMINE: Origin and Action of Mechanism	Darrell Miller	2/6/12
	Does Boron Really Help Improve Bone Health?	Darrell Miller	7/1/11
	Fight Inflammation, Gastric Problems, and Arthritis with Boswellia	Darrell Miller	6/14/11
	Using Cherries to Deal with Arthritis	Darrell Miller	5/25/11
	Hyaluronic acid and your cells, eyes, and skin	Darrell Miller	12/17/10
	Aloe and Inflammation	Darrell Miller	10/13/10
	Hyaluronic Acid can help Restore Joint Function	Darrell Miller	12/1/08
	Glucosamine Sulfate	Darrell Miller	10/2/08
	Essential Fatty Acids	Darrell Miller	7/24/08
	Cetyl Myristoleate	Darrell Miller	5/8/08
	Shark Cartilage	Darrell Miller	4/30/08
	Support Healthy Joint Function With Discount Vitamins	Darrell Miller	11/22/07
	Natural Vitamin and Herbal Alternatives For Joint Health	Darrell Miller	10/18/07
	Do you experience muscle pain and inflammation?	Darrell Miller	4/25/07
	Hyaluronic Acid Double Strength 100mg – w/ Proline, Alpha Lipoic Acid & GrapeSeed extract.	Darrell Miller	4/4/07
	Glucosamine Sulfate and Chondroitin Sulfate	Darrell Miller	3/28/07
	Benefits - Supports joint function and tissue health*	Darrell Miller	12/11/06
	Elan Vital - The Vital Essence of Life - Multi-Vitamin and Mineral Supplement	Darrell Miller	6/1/05

Date: September 29, 2022 01:40 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Chondroitin Sulfate - The Joint Health Superstar You May Not Know About

If you're like most people, you probably haven't heard of chondroitin sulfate. But this humble nutrient is actually a superstar when it comes to joint health. Here's everything you need to know about chondroitin sulfate and how it can help you maintain healthy, flexible joints.

What is Chondroitin Sulfate?

Chondroitin sulfate is a glycosaminoglycan (GAG) naturally present in many body tissues, including joint cartilage and Synovial tissue.* As we age, our bodies' naturally-occurring levels of chondroitin sulfate decline, which can lead to joint discomfort.*Supplementing with chondroitin sulfate can help replenish these declining levels and promote joint comfort and mobility.*

How Does Chondroitin Sulfate Work?

Chondroitin sulfate works by promoting water retention within the joint.* This helps to keep the joint lubricated and cushion it from shocks, as well as maintaining the resiliency of the joint tissue.* In addition, chondroitin sulfate has been shown to inhibit the degradation of cartilage by enzymes.* By doing so, this important nutrient helps to support the maintenance of healthy, flexible joints.*

If you're concerned about your joint health, chondroitin sulfate is a nutrient you should definitely consider supplementing with. This important glycosaminoglycan helps to support healthy joints in multiple ways, including promoting water retention, maintaining flexibility and resiliency, and inhibiting cartilage breakdown. So don't wait - start reaping the benefits of chondroitin sulfate today!

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6474)

Date: October 29, 2013 10:12 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Shark Cartilage and Its Benefit in Improving Joint Health

Benefits of Shark

Shark cartilage is derived from the dried and powdered skeletons of sharks caught in the Pacific Ocean. The part of the skeleton that is used is known as cartilage, which is the tough but elastic part of the skeletal tissue that provides support to the body much like bones. This tissue is rich in calcium as well as other substances thought to have a variety of benefits in health and fitness.

Bodybuilders and fitness experts around the world are currently showing a lot of interest in this product because it has number of effects that can be of benefit to joint health. Depending on the manner in which shark cartilage is harvested and formulated, product can be used to treat cancer, osteoporosis, arthritis and skin disease (psoriasis).

How Does It Work?

As already been mentioned, shark cartilage is rich in calcium. It contains in its formulation other compounds including glucosamine sulfate, chondroitin sulfate and camphor. All these compounds are essential to joint health. When applied topically on the skin covering the joints, shark cartilage is absorbed into the Synovial fluid where it produces its effects.

The glucosamine sulphate, the chondroitin sulfate and the camphor have anti-inflammatory properties and therefore helps with treatment of the common inflammatory disorders of the joints especially osteoarthritis and arthritis and repair of joint damages. When used orally as a dietary supplement, it has the effects of promoting calcification of the bones preventing osteoporosis.

The Uses of Shark Cartilage

Shark cartilage is not only used in joint health. It is also used in the treatment of a variety of cancers (prostate, colon, breast and lungs), psoriasis, eye complications and wound healing. However, there is only limited scientific evidence that shark cartilage can produce these effects.

Those who have used products derived from shark cartilage on the other attest to the efficacy of these supplements especially in improving joint health. Bodybuilders and the elderly who usually suffer from a variety on deteriorating joints can benefit from shark cartilage.

References:

1. //www.bodybuilding.com/store/shark.html
2. //en.wikipedia.org/wiki/Shark_cartilage
3. //www.webmd.com/vitamins-supplements/ingredientmono-909-SHARK%20CARTILAGE.aspx?activeIngredientId=909&activeIngredientName=SHARK%20CARTILAGE

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2865)

Date: February 08, 2012 08:15 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Natural Remedies for Arthritis

Arthritis is a kind inflammation on one or more joint. There are many kinds of arthritis. Each kind has different causes. Most common causes are injury, metabolism problem, immunity disorder, infections, hereditary factors, and much more. The symptoms are various too. But generally, it includes joint pain, swelling, redness, warmth, and stiffness. When the arthritis goes more serious, it could lead to fever, weight loss, and fatigue.

There are many ways to cure arthritis. If the illness is quite serious, you need to go to a doctor. You can undergo a physical treatment. You can orthopedic bracing. Or, you could even need a joint replacement surgery. And if it is not so serious, you can just go to drug store to buy some analgesic, corticosteroid, acetaminophen or some anti-inflammatory medications. But, you need to remember that every drug has side effects. Analgesic could lead you to nausea and stomach upset. Corticosteroid can give make you bruise easily. It can also weaken your bones.

The best recommendation to avoid side effects is to go naturally. Natural remedies have negligible side effects. Those have been used by our predecessors to cure many illnesses effectively. And for arthritis, there are also some ingredients that could be useful. Here are some examples:

1. Curcumin

Curcumin is derived from the root of tumeric plant. Tumeric is commonly used for Indian cooking and Chinese medication. Curcumin can be an effective anti-inflammatory. It can also cure stiffness and pain. For a better result, combine curcumin with bromelain. Curcumin might be not good for a pregnant woman to consume.

2. Boswellia

Boswelia acid can also be an active anti-inflamatory. Commonly, it is used to cure several inflammatory problems such as asthma and some digestive ailments. Boswelia supplements sometimes are sold in capsule form.

3. Holy Basil

Holy basil is also known as Tulsi in India. In Ayurveda, tulsi is very sacred herb. That is why it is called as Holy Basil. In India, many houses have it planted on their yard and often use it to cure headache, influenza, and some digestive disorders. Many researches have found that holy basil also contains high anti-inflammatory and antioxidant. But it is not recommended for pregnant women.

4. Ginger

Ginger has an active compound called gingerol. Gingerol is very effective to cure inflammatory. You can consume ginger in many ways. You can take it as a supplement. You can easily brew the ginger root at home and drink it when it is warm. You can also just eat it. But if you want to eat it, it would be better to eat it with other foods or you might get heartburn.

5. Glucosamine

Glucosamine is the main element that forms cartilage and Synovial fluids. It is formed by glycoaminoglycans and protein inside a human's body. Glucosamine sometimes are formed as glusosamine sulphate. It then is made as supplement and can be bought in a drug store. It is effective for many kinds of injuries and joint disorders.

6. Hyaluronic Acid

Hyaluronic acid is a compound can be found in Synovial fluids, along with glucosamine. It is very important to keep the volume of Synovial fluids and frictionless movement. When a human's body lacked of hyaluronic acid, they will experience an inflammatory conditions such as stiffness, joint pain, and arthritis.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2563)

Date: February 06, 2012 01:08 PM
Author: Darrell Miller (support@vitanet.net)
Subject: GLUCOSAMINE: Origin and Action of Mechanism

Glucosamine is an amino sugar made from glucose and amino acid glutamine. It is a monosaccharide that is found naturally in healthy joints, cartilages, ligaments, muscles and tendons. It helps in the formation and repair of cartilage and other body tissues. Glucosamine is available in the form of dietary supplements, cosmetics and sports drinks. Let us find out about the history of glucosamine and its role in repair and treatment of joint disorders.

HISTORY of GLUCOSAMINE:

Glucosamine was first discovered in 1876 by Dr. Georg Ledderhose. It was prepared by hydrolysis of chitin with Hydrochloric acid. Later on it was developed in sulphate blend. Since then, it has been studied multiple times and in multiple ways to find out its potent health benefits. It has been used clinically in Europe since 1960s. In 1971, researcher K. Karzel glucosamine HCl stimulated the production of glycosaminoglycan layer, which helps in protecting cartilages, ligaments and tendons from normal wear and tear. It became popular in United States in the mid 1990s with the publication of popular bestsellers such as 'The Arthritis Cure' by Jason Theodosakis. Now it has become the most popular selling dietary supplement with sales of $200 million per year.

Glucosamine is naturally found in the body and can be synthetically made from the natural sources of chitin that is found in sea creatures such as shells of shell fish, bones and bone marrow.

How does Glucosamine Works in reducing Joint pain?

Our body's ability to produce glucosamine decreases as we age. Hence after any kind of injury cartilage, spinal discs and joints, the body may not be able to heal optimally. Aging and glucosamine depletion in the body leads to joint degradation. However, glucosamine supplementation can support cartilage and CT-integrity limiting degeneration.

Glucosamine supplements do not work like NSAIDS, which are known to have anti-inflammatory and analgesic effects on the body. The exact mechanism of significant analgesic effect of glucosamine supplements is unknown but according to various studies, glucosamine has no effect on cyclooxygenase system. Studies have shown that glucosamine stimulates synthesis of proteoglycan in a dose dependent manner. It helps in stimulating the production of cartilaginous matrix, hence counteracting the degrading loss of cartilage in case of arthritis or injury.

Several important studies demonstrate the role of glucosamine in stabilizing cell membranes, inhibit lysosomal enzymes and reduce the generation of oxygen free radicals by macrophages. It may inhibit interleukin 1 induced nitric oxide activity that leads to chondriotic cell death. Hence it increases aggrecanase activity that helps in preservation of proteoglycan.

Glucosamine along with Chondroitin sulphate stimulates synthesis of cartilage precursors as well as Synovial fluid. They also limit the degradation of existing cartilage in any loss of joint integrity.

This non rapid acting drug has many beneficial effects in reducing the symptoms of osteoarthritis. It is a powerful joint repairing supplement that rebuilds joint cartilage. Glucosamine supplements have been thoroughly evaluated to find out any potential side-effects. However, it has been proved that it does not have any of the side-effects of NSAIDS, surgery or opiods.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2555)

Date: July 01, 2011 11:06 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Does Boron Really Help Improve Bone Health?

Boron and Bone Health

Boron is now widely considered an essential mineral, though its daily value is still a matter of debate. The physiological roles of this chemical element in the human body were unknown in the first half of the 20th century, but in recent years scientific research has proven that it is necessary for the calcium metabolism and vitamin D utilization, both of which significantly contribute to overall bone health.

There has not been any figure set in the dietary reference intake for boron largely owing to the fact that its nutritional importance has not been discovered until recently. As a result, important data on the safety of boron intake as a dietary mineral remains under investigation. Nonetheless, the scientific community is convinced that the presence of boron is required for many different metabolic processes.

Plants need relatively higher amounts of boron to survive. It follows that plant-based foods are very good sources of dietary boron whereas animal products have negligible amounts of this element. This chemical element was first noted to have a positive effect on joint health. The studies that followed have been observed that boron supplements alleviate symptoms of osteoarthritis in human trials.

Promotes Bone Health

Concentrations of boron in the Synovial fluid and joint cartilage help determine the health of joints and bones. It has been reported that people who have higher amounts of elemental boron rarely develops degenerative joints diseases like osteoarthritis and symptoms of joint pain. Also, epidemiologic studies have shown that populations noted for healthy consumptions of boron have lower incidence of arthritis.

More recent studies have shown that boron intake is directly proportional to bone density. For one, it has been documented that supplementation of boron has an impact on bone strength in patients with osteoporosis. Clinical trials have produced very promising results as far as the treatment of bone loss is concerned. There is very good scientific evidence that boron supplements are superior to placebo.

Inhibits Bone Resorption

The skeletal system is the primary depot for minerals in the human body. Chemical elements obtained from the diet are stored in the bones or otherwise utilized by tissues and organs. In particular, more than half of the overall body concentrations of calcium, potassium, and magnesium are found in the bones, which are constantly remodeled to draw minerals out in response to the needs of body tissues.

The process of bone resorption is responsible for releasing the minerals from the bones into the blood. On the other hand, the process of bone resorption takes care of building bone tissue. If consumptions of dietary minerals are insufficient, resorption exceeds formation, as is the case with osteoporosis. The presence of boron promotes mineral retention in the bones, thereby increasing bone mass and density.

If you are experiencing osteoporosis, give boron a try!

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2356)

Date: June 14, 2011 11:49 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Fight Inflammation, Gastric Problems, and Arthritis with Boswellia

How Does Boswellia Fight Inflammation.

Boswellia fights inflammation through the action of a family of anti-inflammatory terpenes known as boswellic acids. Inflammation is a natural reaction of your immune system to tissue damage and infection, and is often associated with conditions such as arthritis, sports damage to bones and joints and bacterial infections caused by cuts and grazes. There are more serious inflammatory conditions of course, such as asthma, and boswellic acids act in the same way as non-steroidal anti-inflammatory drugs (NSAIDS) without their unwelcome side effects.

Among the causes of inflammation are inflammatory mediators such as leukotrienes, the biosynthesis of which is blocked by boswellia. Another is the 5-lipoxygenase enzyme, also known as LOX-5, and again, the terpenoid anti-inflammatory boswellic acids block this so that the causes of inflammation in the above conditions are severely restricted. Boswellia extract is a good supplement to take for those suffering any form of arthritis, joint pain or even asthma.

Using Boswellia to treat Arthritis

Boswellia can be used to treat both osteoarthritis and rheumatoid arthritis, although rheumatoid arthritis is not always easy to control. Arthritis is an inflammatory condition, in the case of osteoarthritis the inflammation being a natural response to joint damage and infection of the Synovial fluid generally caused by wear and tear on the joint with aging, and also by sports injuries.

Rheumatoid arthritis is a form of immune disease caused by the body attacking its own joints, and while the terpenoid anti-oxidants known as boswellic acids can help to mediate the pain and other symptoms, it can do nothing to cure the condition.

If you are suffering pain through arthritis, and your joins are tender and swollen, a supplement consisting of an extract of boswellia or its terpenes can help to relieve these symptoms and to offer pain relief equivalent to that offered by synthetic NSAIDs such as aspirin and Ibuprofen.

Gastric Problems and Arthritis Pain? Perhaps Boswellia Can Help

Extracts and supplements based on the resins of the boswellia tree are commonly used to treat inflammatory conditions, and reduce the severe pain of rheumatoid and osteoarthritis, ease the discomfort of colitis and also help ease the symptoms of those suffering asthma. Each of these is an inflammatory condition that would otherwise have been treated using NSAIDs, or non-steroidal anti-inflammatory drugs.

NSAIDs have a number of side effects, being particularly unsuitable for those with ulcers or any other gastric problem. The terpenoids contained in boswellia extract an effective alternative to these drugs that many try to avoid taking. Long-term use of boswellia appears a lot safer than long-term use of NSAIDs, since it doesn't promote the severe gastric problems of these synthetic drugs, such as irritation of the stomach lining or even ulcers. If you already have ulcers or other gastric problems then NSAIDs area define no-no for you, and boswellia is the ideal substitute.

Grab some boswellia today and experience relief for your self!

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2336)

Date: May 25, 2011 03:41 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Using Cherries to Deal with Arthritis

Call it what you will: arthritis, osteoarthritis, rheumatoid arthritis or gout - cherries can deal with it and enable you live and sleep more comfortably than without them. When the bones and lubrication systems of your joints become worn you begin to feel pain - not because your bones are grinding against each other but because of the inflammatory response of your immune system.

Your cartilage begins to wear and your body reacts to the damage first by activating cells already close by - macrophages, mastocytes, dendritic cells and so on, and then calls on the release of leukocytes such as neutrophils. Your blood vessels dilate to enable the large cells to get to the general area of the problem, and then leak to enable fluids to get right to the exact spot where they are needed.

With arthritis, the joint swells because of the above actions, and the Synovial fluid can become infected and inflamed. The temperature around the joint increases in temperature to render it less attractive to invading cells and pathogens, and you feel pain because of the pressure on your nerve endings. Then you should take some cherry extract.

The activity of the cytokines and prostaglandins that are creating this situation is suppressed, and the temperature starts to drop. The blood vessels are contracted and the situation begins to return to normal. One more bout of inflammation successfully dealt with, and now that you understand what has caused it you will be better placed to get the cherry extract down your throat next time.

Buy It And Try It Today!

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2307)

Date: December 17, 2010 10:48 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Hyaluronic acid and your cells, eyes, and skin

Hyaluronic Acid

Discovered in 1934, hyaluronic acid can be found anywhere there is the need for connective tissue in your body. Your joints, your eyes and your heart all contain hyaluronic acid, and a shortage can lead to a wide range of bodily defects, including the appearance of accelerated aging. It is a glycosaminoglycan, a form of polysaccharide that is not only found in connective tissue and epithelial and neural cells, but is also important in the growth and renewal of body cells.

We shall discuss here how hyaluronic acid affects specific areas of your body, and what the effect of a deficiency would mean, but also keeping in mind that an excess of this polysaccharide can also have a serious impact on your health although it offers few side effects worth noting.

Hyaluronic Acid and Your Joints

The highest concentrations of hyaluronic acid (HA) in your body is found in the Synovial fluid, the fluid lubricating contained in your joints, and it is also plays an important role in maintaining the function of cartilage in keeping your joints flexible and well cushioned. It is chemically a glycosaminoglycan that is formed from glucosamine and glucuronic acid. Its production is boosted by chondroitin, which is why glucosamine and chondroitin are commonly used supplements for the treatment of arthritis.

Specifically, HA joins with collagen and elastin to produce cartilage, and also increases the supply of Synovial fluid that maintains lubricity within the joints. Without the Synovial fluid your cartilage would soon become worn away and your bones would grind together, eventually seizing up. By taking hyaluronic acid orally as a supplement, you can help to maintain healthy joints by maintaining the integrity of the cartilage and the quality of the Synovial fluid.

Because the cartilage contains no blood vessels, it is reliant on the Synovial fluid to keep it supplied with nutrients, and specifically with HA which is a large part of its structure. Without this important polysaccharide your body would not be able to function: no mobility, dry flaky skin and poor or no eyesight.

Hyaluronic Acid and Your Skin

Hyaluronic acid occurs in the lower layers of your skin where it helps to maintain a smooth and full appearance to your skin due to its hygroscopic nature in absorbing up to a thousand times its weight of water. For this reason HA is frequently used in skin moisturizing treatments and lotions.

HA is not found inside body cells, but appears to be restricted to the extracellular regions between cells where its moisturizing properties are critical in maintaining suppleness. Elastin requires copious quantities of water to remain elastic or it would otherwise become brittle: that is why our skin looks dry and wrinkled when we age. It is due to a lack of moisture: the moisture that hyaluronic acid can bring to the table. The problem is that HA reduces with age and in order to maintain our youthful looks we have to take a supplement.

Hyaluronic acid doesn't last long in your skin: it has to be renewed constantly and each day about 50% of the HA content of your skin is lost. It takes about two weeks for the same degree of loss to occur in the Synovial fluid of your joints. The look of your skin depends to a very large extent on the extracellular matrix, or what is contained between your skin cells. The more moisture there then the smoother and plumper your skin will appear.

As you age, your hyaluronic acid production drops and so your skin becomes increasingly more depleted of moisture. This causes it to dry up and wrinkle. Were there one substance that I would choose as the elixir of life it would be HA, because by taking a regular supplement your natural daily loss is replenished and your skin is given a hand to maintain its soft, moist plumpish look that helps you to keep you looking young.

Hyaluronic Acid and Your Eyes

The vitreous humor is the liquid inside your eyeball, and it contains a large amount of hyaluronic acid. It helps absorb shock and to maintain the shape of the eyeball. The HA is so important that your body has developed a special set of cells known as the hyalocytes of Balazs that are believed to promote the renewal of hyaluronic acid, and also possibly its breakdown.

There is still a lot of research going on into this but the importance of HA in the vitreous humor and other aqueous area of your body is not in question. It helps to retain water and give structure to the liquid media within your body, whether that is between the bones of your joints, in the dermal and epidermal regions of your skin to keep it supple, or in your eyeball. In fact, it is believed to take up 70% - 80% of your eye, and helps to keep the retina in place exactly where it has to be for your eyesight to work.

Because Hyaluronic acid is:

a) present between the cells in every tissues in your body, and

b) a consumable, in that it gets used up rapidly, and

c) your biochemistry's ability to regenerate it reduces with age,

a supplement is the ideal way in which to maintain its levels in your extracellular system. In some instances injections are given, particularly in expensive anti-wrinkling treatment, but studies have shown that hyaluronic acid baxyl taken as an oral supplement shows an improvement after an average of 3 months treatment.

It should be understood that the average person has around 15 grams hyaluronic acid in their body, of which 5 grams is continually degraded and synthesized daily. When you reach an age that your ability to generate HA is impaired, then an oral supplement will be less expensive than injections, the hyaluronic acid of which will also be degraded with time. It won't be long before you need more treatment, and oral supplements are less expensive than private hypodermic injections.

A Hyaluronic acid supplement baxyl can be taken to improve the suppleness and appearance of youthful skin, help maintain the integrity of your eyesight and help to reduce the symptoms of arthritis and many other conditions brought on by a reduction in the Synovial fluid and hydration of the skeletal and connective tissues of your body. In other words, it helps to keep you looking younger for longer and to keep your joints and your eyesight in good health.

Have you had your daily dose of hyaluronic acid today?

Baxyl is a liquid form of hyaluronic acid that is easy to take and easily assimilated into the body because its a liquid.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2210)

Date: October 13, 2010 12:40 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Aloe and Inflammation

It is well known by those that use it as such that Aloe Vera is a powerful anti-inflammatory that fights inflammation both internally and externally. If you suffer from arthritis, it can be used to reduce the swelling and the pain caused by the inflammatory response of your immune system to the aggravation caused by wearing joints and infected Synovial fluid.

Aloe Vera A gel or Cream

Rheumatoid arthritis is caused by your immune system attacking your own joints, and Aloe Vera goes a long way towards mediating this and reducing its effects. It is by no means a cure, but offers relief from pain and swelling while also supporting your immune system. It also displays its anti-inflammatory properties in soothing the effects of acne, eczema and other inflammatory skin conditions such as sunburn.

So if you suffer any of these inflammatory conditions, or intend spending time in the sun this summer, make sure you have some Aloe Vera cream or juice close by - you might need it!

Try Aloe Vera Today!

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2190)

Date: December 01, 2008 10:03 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Hyaluronic Acid can help Restore Joint Function

Hyaluronic acid, also known as hyaluronan, is one of the main components of the extracellular matrix of connective tissue and joints, and is one of the main chemicals contained in the Synovial fluid that lubricates your joints. Before we discuss how it can be used to help restore the function of damaged joints, let's have a look at what causes joint pain, and why joints can break down long before their time.

You might have heard that arthritis is an inflammatory condition, or that it is due to the immune system. This is true to an extent, and rheumatoid arthritis is an immune system problem, although osteoarthritis is a different problem altogether. Arthritis is not the only cause of joint pain of course, but is by far the most common cause. As already inferred, there are two forms of arthritis, each with a different basic cause.

Osteoarthritis is the most common form of joint disease, and is largely due to wear and tear, injury or can be hereditary. However it is usually initiated by damage, the joint surface becomes roughened and the bone around the damaged area gets thicker to compensate. A joint is where two bones meet, and not all joints move. You have the fixed joints in your skull, for example, and those between the ribs and the spine. However, arthritis generally affects the joints associated with movement, mainly the knees, hips, fingers, toes and elbows.

The ends of the bones are covered with a thin layer of cartilage, which can absorb shocks and both cushion the joint and allow the ends of the bones to move smoothly over each other. Round each joint is a membrane known as the synovium that is filled with the thick Synovial fluid, which lubricates the cartilage. The bone ligaments hold them close to the joint, and prevent them moving too much and dislocating. Finally, the joint is completed by the tendons that attach the muscles to the bones they control.

Osteoarthritis causes a joint to deteriorate: the cartilage becomes rougher and wears, and the bone beneath the cartilage gets thicker. At the edge of the joint the bone tends to grow outwards, forming spurs and the synovium swells producing extra Synovial fluid. This causes swelling and pain, and ultimately the joint can be damaged beyond repair. This process takes a number of years to reach a stage whereby pain and discomfort are felt.

Before that situation occurs, however, the joint tries to repair itself, and hyaluronic acid can take part in this process. It is mainly involved in the reparation of connective tissues such as cartilage, although there are other connective tissues which hyaluronan has been found to repair. These include skin, eyes and heart valves and hyaluronic acid can arguably be used to help repair all of them.

However, it is joint tissue with which we are concerned here, and hyaluronan is an important component of articular cartilage: the type of cartilage involved in movement (knees, hips, etc), as opposed the type that forms your nose or the external part of your ears. It is believed that injections of hyaluronic acid can help to repair damaged articular cartilage. However, osteoarthritis is only one of the two forms of arthritis. The other is rheumatoid arthritis, and this is much more sinister.

Rheumatoid arthritis is caused by the attack of your joints by your own immune system, although why this happens is unknown. The most likely theory is that certain infections trigger the immune system, and it then proceeds to attack the Synovial joints. Cytokines are responsible for inflammation of the Synovial fluid, which can also cause fever, loss of weight and appetite, and inflammation of the blood vessels.

The body tries to generate more Synovial fluid which causes swelling round the whole joint, putting pressure on the damaged areas, and generating even more pain. The inflammatory response commences and the whole area becomes seriously painful.

The smaller joints are most commonly affected, such as the fingers and toes, but it can progress to the elbows, hips and the knees. The joints become red, swollen and finally too stiff to be used. The sinusitis eventually leads erosion of the joint and deformation.

Because hyaluronic acid behaves like the Synovial fluid, it is believed that it can be used to treat both forms of arthritis. It is a glycosaminoglycan, an unbranched polysaccharide of the same type as chondroitin sulfate that is commonly used to treat arthritis. It can be used to increase the viscosity of the Synovial fluid, and render a more effective lubricant.

However, it is in treatment of osteoarthritis that hyaluronan is most likely to find success. It is used to improve the viscosity of the Synovial fluid, so providing increased lubrication to the joint and helping reduce the pain. In fact it not escaped notice that those who eat a diet rich in hyaluronic acid tend to live longer and look younger than those that do not do so.

Commercial preparations are currently in use or under evaluation for disorders such as glaucoma, fractures, and detached retinas, damage to cartilage, healing ligaments and osteoarthritis. These last three are particularly of interest to arthritis sufferers, and signs are that they are effective with many cases.

However, it has also been established that smoking cigarettes can negate the effect of hyaluronic acid, and excessive levels of Vitamin C can also degrade it. Estrogen treatment, however, can enhance its effect in repairing connective tissue. Zinc deficiencies have also been found to have negative results, so make sure that these factors are addressed if you are using hyaluronic acid to treat arthritis.

Something to keep in mind if you are taking hyaluronic acid orally is the size of the molecule. It is a very large molecule, and suffers from the same absorption problems as chondroitin sulfate. There are smaller hyaluronan molecule versions available if you can find them, that improve the absorption through the intestine, but if not then the dose will generally be greater than expected due to the low absorption levels due to the molecule being too large to be easily absorbed through the tissues into the bloodstream.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1942)

Date: October 02, 2008 09:36 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Glucosamine Sulfate

It is possible to rebuild joint cartilage with glucosamine sulfate, although how quickly that occurs could depend upon what you take with it. First, though, an understanding of exactly why cartilage deteriorates will be useful in your understanding of how glucosamine sulfate can help towards repairing the damage.

Cartilage has several roles to play in your body, an example of which is to form curved body parts that would otherwise be unsupported, such as the external contours of your ears or a large part of your nose. Without cartilage you ears and nose would flop around a lot, and it is also contained in the spine, to prevent your discs from grinding against each other.

However, the part that we are interested in is as a shock absorber between the bones of your joints. It allows bones to slide over one another without damage, either through friction or shock, and is also nature’s shock absorber, helping to support your weight while you are active. Thus, your cartilage protects from impact damage when you are running or jumping down from a height. This type of cartilage, known as articular cartilage, is bathed in a lubricating fluid known as Synovial fluid, which introduces its own problems when your cartilage becomes damaged.

This damage can occur in several ways: as the result of a fall, for example, or direct contact with the joint when playing a physical contact sport such as football or soccer. It can also become damaged through wear and tear over a period of time, such with long distance runners or soccer players (again), and is also associated with age. Many years of continual use, especially amongst those with active rather than sedentary occupations, eventually lead to wear and damage.

Problems with the joint structure itself, known as osteoarthritis, can also damage the cartilage, as can being overweight for a lengthy period. You can also experience cartilage damage if you are bedridden or other wise immobile for long periods, because the cartilage needs regular movement to function correctly. This is connected with the blood supply, which will be discussed shortly.

Cartilage is constructed of cells known as chondrocytes that generate a fibrous matrix known as collagen, a mixture of amino acids known as elastin that allows the cartilage to return to its original shape after deformation, and non-collagenous matrix tissue containing proteins, water and proteoglycans that contain sulfated glycosaminoglycan chains. That last mixture is often referred to as ‘ground substance.’

One of the problems with cartilage is its lack of a direct blood supply, and it relies on the compression and decompression of the articular cartilage, or on the flexing of elastic cartilage, to create a pumping action that drives blood to the chondrocytes. This is why inactivity can cause cartilage damage, due to a lack of blood supply, and why it is repaired more slowly than other body components.

Once an injury or wear and tear damages a joint, the body’s natural defense, the immune system, is activated, and the major part of that involved in cartilage damage is the inflammatory response. The joint becomes inflamed, the quantity of Synovial fluid is increased to provide more protection and swells the joint, and enzymes (hyaluronidase) are produced which, although part of the natural defense system, actually degrade the Synovial fluid and the cartilage.

This increases the amount of inflammation and the process becomes self-perpetuating, leading to the condition known as degenerative joint disease (DJD) because the body is unable to produce enough glucosamine to generate the proteoglycan needed for repair.

This is where glucosamine sulfate enters the scene. Glucosamine is a precursor for glycosaminoglycans (GAG), which as mentioned as above are components of proteoglycans in the cartilage matrix ground tissue. It has been shown to stimulate the biosynthesis of proteoglycan, and analysis has shown its presence within articular cartilage after administering it orally to patients with cartilage disease. It therefore makes its way to the right place.

Glucosamine is administered in the form of glucosamine sulfate, the highly electrically charged sulfate groups believed to aid in the compression properties of cartilage. It is rapidly absorbed into the bloodstream, although only about a quarter of the oral dose is eventually available to the body, and high concentrations accumulate in the liver, kidneys and in articular cartilage where it is used in the biosynthesis of GAG.

When in solution, glucosamine sulfate separates into ions: sulfate and glucosamine. Glucosamine ions are involved in the synthesis of GAG, that then combine with proteins to form proteoglycans, a component of the non-collagenous matrix of the cartilage. Although glucosamine is the major active component, there is evidence that the sulfate group contributes the stability of the matrix of the connective tissue since the uptake of sulfate ions increases with the amount of glucosamine sulfate used.

Another consideration here is that sulfate is an important part of proteoglycans, and glucosamine sulfate promotes not only the synthesis of glycosaminoglycans, but also of proteoglycans in general. Glucosamine is also active in regenerating the lubricating properties of the Synovial fluid, and in hindering the activity of hyaluronidase, the enzyme that breaks down the hyaluronic acid in the Synovial fluid.

Some people find that glucosamine, taken either alone or in conjunction with chondroitin sulfate and/or methyl sulfonyl methane (MSM), is more effective than the non-steroidal anti-inflammatory drugs (NSAIDs) used to reduce inflammation (e.g. Aspirin and Ibuprofen) and without the side effects of these substances. MSM contains dietary sulfur, which is necessary for cell structure and healthy cell repair. Methyl sulfone methane is know to be beneficial for painful conditions such as arthritis, and also improves the blood circulation. It might also play a part in helping glucosamine sulfate get to the site of the cartilage damage.

Glucosamine is a large molecule, however, and finds it difficult to make its way to the area around the joint due to the lack of a direct blood supply. It is therefore taken in relatively large doses to ensure that sufficient amounts get to where it is needed. Many people insist that glucosamine sulfate is very effective in reducing, or even eliminating, their pain, and it is finding increasing popularity in the treatment of arthritis and other conditions involving cartilage damage.

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Date: July 24, 2008 11:19 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Essential Fatty Acids

A balance in essential fatty acids is crucial for many bodily functions. It promotes good overall health as well. Particularly, omega-3 fatty acids are essential for human development and achieving good health throughout life. The tissues of the body require omega-3 and omega-6 fatty acids in order to function properly. There are many conditions that are improved by supplementing with omega-3 oils including high cholesterol levels, prevention of strokes, cancer prevention/treatment, psoriasis and eczema, heart disease, high blood pressure, multiple sclerosis, and rheumatoid arthritis.

Diets that are high in saturated fat are often linked with high blood-cholesterol levels, which is a risk factor for cardiovascular disease such as coronary heart disease and stroke. Many diet therapies that aim to reduce the build-up of cholesterol and risk of CHD focus mainly on reducing the total and saturated fat intake. Dietary interventions that reduce saturated fat intake by simply three percent could even prevent about 100,000 new cases of coronary heart disease within the next 7 years. Once dietary saturated fats are decreased, they may be replaced with polyunsaturated fats, such as omega-3 fatty acids that lower both total cholesterol and LDL-cholesterol.

Although a person’s genetic inheritance has a lot to do with the likelihood of developing heart disease, it is becoming increasingly clear that modifying your lifestyle can improve the effects of your genes. Heart disease remains the leading cause of death in the U.S., but people can reduce their risk by adopting prevention habits. Some of the most crucial tactics are avoiding smoking, maintaining a desirable blood cholesterol level, keeping blood pressure in the normal range, and regularly engaging in aerobic exercise. Along with these lifestyle habits, alpha-linolenic acid can be taken as supplementation to improve the body’s ability to fight heart disease.

Alpha-linolenic acid has also been shown to lower the risk of stroke, which is the third leading cause of death in the U.S., after heart disease and cancer. Omega-3 fatty acids have also been shown to lower blood pressure by small but significant amounts and have also been able to lower levels of hypertension. Essential fatty acids also have the ability to reduce inflammation of the Synovial fluid in the joints, which means that they can help in rheumatoid arthritis, a disease that affects at least forty million people in the United States.

Multiple sclerosis, a disease of the central nervous system that destroys myelin sheaths that cover the nerve and creates inflammation, has symptoms including blurred vision, dizziness, numbness, weakness, tremors, slurred speech, and staggering. Studies have shown that multiple sclerosis is at least partially caused by the deficiency of prostaglandins, which are produced from essential fatty acids.

Psoriasis, a skin disease that is characterized by patches of scaly skin on the knees, elbows, and scalp, but possibly anywhere, is considered essentially incurable by conventional methods, but dietary methods have offered some hope. Because of its rich essential fatty acid content, flaxseed oil is one of the natural therapeutic agents suggested for psoriasis. There is some evidence that suggests that a consistent supply of omega-3 oils may help to prevent fat-sensitive types of cancers, as well as inhibit breast, colon, prostate, and pancreatic cancers.

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Date: May 08, 2008 03:47 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Cetyl Myristoleate

Cetyl myristoleate is a fatty acid ester used largely as a dietary supplement to support joint mobility and the immune system. Chemically it is a natural hexadecyl ester of cis-9-tetradecanoic acid, an unsaturated fatty acid commonly known as myristoleic acid.

The acid is found naturally in fish and whale oils, and also in butter and kombo butter from the kombo nut. The ester is of a buttery consistency at normal room temperatures, and turns waxy when cooled, and it has no known uses other than as a health supplement, particularly for the treatment of arthritis and other inflammatory and immune system problems.

The substances appear to have similar therapeutic characteristics to unsaturated essential fatty acids, but with a stronger and more long lasting effect. It also appears to work in three distinctly different ways in that it acts as a joint lubricant, supports the immune system and functions in the same way as essential fatty acids.

Arthritis is a disease that has reached epidemic proportions worldwide, and it is estimated that more than 50 million Americans are affected by it. Until recently it was believed to be a disease of the aged, or associated with physical injury, but is now known to be more complex than that, with many manifestations and causes. Because of this, no single treatment is effective with all forms of arthritis, but cetyl myristoleate is the new kid on the block that is believe to make a significant contribution to the treatment of non-infective forms of the disease.

However, it was not always known, and a search in the textbooks for cetyl myristoleate prior to 1977 would have yielded nothing. Why 1977? It started with Harry W Diehl, a sugar chemist with an interest in the treatment of arthritis. While carrying out research on arthritis in mice, he was working on thin layer chromatographic analysis of a methylene chloride extract of macerated mice. He noticed a separation that was unknown to him, which was subsequently identified as cetyl myristoleate.

He had been unable to induce arthritis in mice, and believed that if he found out how to do that, then he should also be able to establish what made the mice immune to the disease, and so establish a cure. He soon established that it was this cetyl myristoleate circulating in the blood that protected the mice, and then found a way of synthesizing it in the lab by esterifying myristoleic acid.

Since the compound was unknown at that time Diehl patented it in 1977, hence the date. Apart from in mice, it has subsequently been found only in whale oil and in one of the glands of the male beaver, with no other known sources at the time of writing. There have been several studies that have supported the effect of cetyl myristoleate on arthritis, the first human study being in 1995 when 46 out of 48 arthritis patients showed significant improvement in articular mobility and reduction in pain. Others since have demonstrated similar results.

So how does it work? What is the mechanism by which this hitherto unknown substance helps to relieve the symptoms of osteo and rheumatoid arthritis? Being a fatty acid ester, cetyl myristoleate possesses lubricant properties, and one of its properties is to supplement the Synovial fluid that lubricates the joints and tendons. This helps to keep the joints moving freely, and reduces their tendency to grind when the connective tissue wears. It also lubricates entire muscle groups, allowing them to slide over each other more freely, and also over bones allowing a smoother movement of the joints.

The second way, in which it operates, by supporting the immune system, is particularly appropriate to the treatment of rheumatoid arthritis which is caused by the immune system attacking the body’s own joint and connective tissue. In this respect, cetyl myristoleate has also been found effective in treating other immune system conditions such as multiple sclerosis and lupus erythematosus.

Finally, it also possesses the mediation effect on the inflammatory reaction possessed by other essential fatty acids. This helps to reduce the effect of inflammation that causes much of the swelling and pain of arthritic conditions, although it occurs much faster than with other fatty acids. When taken together, all of these effects have a powerful effect in reducing the unpleasant symptoms of both osteoarthritis and rheumatoid arthritis. Swelling is reduced, mobility is improved and pain is alleviated. Improvements have been reported by sufferers of both types of arthritis, and in fact it is reported that Harry Diehl successfully treated his own arthritis with the substance before any other human tests had been carried out.

Cetyl Myristoleate is now used word-wide in significant quantities, and there have as yet been no confirmed reports of adverse side effects. However, as with many otherwise safe supplements, it is recommended not to be taken by pregnant or lactating women until it has been proved to definitely have no side effects on the fetus or young babies.

Although there is no definitive scientific evidence of the effectiveness of the substance in relieving the symptoms of arthritis, there is an overwhelming body of evidence from those that have used it world wide. The accepted treatment is by non-steroidal anti-inflammatory drugs (NSAIDs), and with over 16,0000 NSAID-related deaths in the USA alone each year, cetyl myristoleate is certainly worth considering as an alternative for arthritis sufferers. Not only that but there is a very significant price differential, with NSAIDs costing 5 – 10 times that of cetyl myristoleate.

Among the other benefits that people using the substance have reported are beneficial effects on psoriasis, hepatitis, high blood pressure, eczema, allergies, headaches and many more. Although many of these might be coincidence or psychosomatic, it cannot just be coincidence that many of them, such as psoriasis and allergies, are related to the immune system.

However, anybody with asthma or a history of severe allergic reactions should consult their physician before using the substance. That aside, there is more than enough popular evidence to indicate that cetyl myristoleate is effective in the treatment of arthritis in all its forms, and also good for your general state of health and wellness.

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Date: April 30, 2008 03:03 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Shark Cartilage

Sharks do not have skeleton of bone but of cartilage, which is a dense form of connective tissue. Its main components are cells known as chondrocytes that are responsible for producing collagen fibers, an elastic protein called elastin that is responsible for the skin returning to its original shape after being pinched, and ground substance that is rich in proteoglycan, a protein with glycosaminoglycan chains.

Shark cartilage is said to be beneficial in the treatment of many conditions including arthritis, psoriasis (allied to arthritis), rheumatism, eczema, acne, allergies and the most controversial – cancer. It is said to inhibit tumor growth by inhibiting angiogenesis – the formation of new blood vessels by growing them from old ones. This can lead to metastasis, or the spread of cancer between organs and also feed the cancer cells with blood.

Shark cartilage has been used medicinally for thousands of years, particularly in ancient China where its use is documented, and might also have been in other areas where the consumption of fish was high. However, the production of shark cartilage and its trade is not well documented. The major cartilage consuming countries are Australia, India, Japan and the USA, although it is used or consumed in many other countries, especially Hong Kong, Taiwan, China and, increasingly, Europe.

The best quality of cartilage is from the blue shark due to its higher chondroitin quality. Chemically, chondroitin is an acid mucopolysaccharide, and a very large molecule that is used for a variety of purposes. In arthritis it is difficult to get it to the source of the problem due to its physical size and large doses are used to ensure that at least a proportion passes through the capillaries to the joints.

Arthritis is a particularly prevalent disease and comes in two forms: osteo- and rheumatoid arthritis. Osteoarthritis develops over a long period of time, and generally the cartilage roughens and becomes thin, while the bone becomes thinner. Extra Synovial fluid, that lubricates the joint, can be formed and that causes swelling. The bone tried to repair itself, but degeneration continues and the tendons become affected. Eventually inflammation can occur leading to severe swelling and pain. There are several causes, the most common being injury or repetitive hard use of the joints.

Rheumatoid arthritis, on the other hand, is completely different, and is caused by the immune system rather than wear and tear. The immune system mistakes parts of your joints as being foreign, and attacks the Synovial membrane, or lining of the joint. It might also attack the sheath around the tendons. This eventually causes the cartilage to thin and the joints to wear, and the inflammatory response can cause painful inflammations. There is no apparent cause, though heredity, lifestyle and hormones might all be connected.

The effect of shark cartilage on arthritis is well documented, and in one study in the 1970s, only 11% of patients did not respond well to a treatment of cartilage injections. The pain relief the injections provided lasted from six weeks to over a year, though no reason could be provided for the vast difference. However, it did seem to demonstrate that the remedy was more than just a placebo. In another study involving bedridden osteoarthritis patients, eight out of ten could leave their beds after only three weeks of oral cartilage treatment. Shark cartilage appears to be effective when administered both intravenously and orally.

In a later placebo study involving 147 arthritis patients, they were given either shark cartilage or a placebo. Those with the placebo were encouraged to use other treatments when their pain became severe. After five years the placebo group reported a 5% drop in pain scores compared to 85% of the group taking shark cartilage. The joint deterioration in each group was assessed, and was considerably less in the cartilage group, who also lost less time at work through pain.

All of these results indicate that shark cartilage can be used to relieve osteo- and rheumatoid arthritis pain in at least 60% of sufferers. Since rheumatoid arthritis has been linked to psoriasis, this could also explain its effects on psoriasis. What the studies did indicate is that you need not wait five years to find if the treatment is effective or not: if you do not experience positive results within between four and six weeks, then shark cartilage treatment will likely not work for you.

There is no doubt that shark cartilage can provide relief to painful, swollen joints, and this is likely due to the mucopolysaccharides. It can also prevent the undesirable growth of new blood vessels into the cartilage and appears to help to regulate the immune system. These are also two of the reasons why it is believed by some to be an effective treatment for cancer by preventing metastasis.

It was the publication of the book “Sharks Don’t get Cancer” that started the rush for shark cartilage as a a treatment for cancer, but the problem is that sharks do get cancer – they even get cancer of the cartilage! However, that does not mean that the scientific reasons for the inhibition of metastsis are invalid. They are valid, and it is metastsis rather than the original cancer that ferquently leads to death. Metastsis is the spread of the disease round the body by the bloodstream, and shark cartilage appears to be able to help to prevent that. It also prevents the growth of blood cells into cancerous areas to feed the cancers with oxygen and other nutrients.

Although there are few reported side effects of shark cartilage, in the interest of safety it is advised that children and pregnant women should avoid it. The same is true of people recovering from recent surgery since it could slow healing due to its effect on repairing blood vessels. If you have a low white blood cell count, do not have a shark cartilage enema since it can cause a potentially fatal infection.

Otherwise it should be safe to take, and is available in many forms including creams, capsules, powders and injections. The recommended dosage is 1 gram dried shark cartilage for each 7 Kg (15 lb) body weight. Once you begin to see an effect on the pain of your arthritis, one can then try to reduce the dose to 1 gram for each 18 Kg (40 lb) body weight.

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Date: November 22, 2007 11:05 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Support Healthy Joint Function With Discount Vitamins

The joints are very important to your mobility and it is essential that you support health joint function with discount vitamins. The reason for discounted vitamins is that there is no need for you to pay more than you have to, and good healthy bones and joints need a good supply of several vitamins, minerals and other substances to remain healthy throughout your lifetime.

Vitamins C and D, and calcium and magnesium are the more common supplements that help to promote joint health, but glucosamine, chondroitin and gelatine also play a large part. Although the strength of the bone is important, it is disorders of the connective tissue that are mostly responsible for joint problems. Connective tissue holds the joint together and prevents excessive friction between bones.

Arthritis in both its forms – osteoarthritis and rheumatoid arthritis – is characterized by a reduction in the cartilage tissue that provides a lining between the bones that make up the joint. As the cartilage becomes worn or its structure destroyed, the bones are exposed to each other and this causes the frictional damage that is osteoarthritis. With rheumatoid arthritis, on the other hand, the connective tissue and cartilage are attacked by the body’s immune system, causing inflammation. The reason for this is still unknown, but the inflammation leads to swelling of the joint and severe pain.

Both of these conditions can be helped by the use of glucosamine, a natural substance produced by the body to form cartilage and stimulate the formation of connective tissue. Normally taken in the form of the sulfate, glucosamine reduces arthritic pain, and over time can start to rebuild the lost cartilage. It is best taken in conjunction with chondroitin sulfate which is a substance also contained in cartilage and connective tissue.

A discount vitamin supplement containing glucosamine and chondroitin can help to avoid these conditions from occurring. Rheumatoid arthritis also responds well to anti-inflammatories and antioxidants. Much of the damage to the joint tissues can be caused by the action of free radicals that are aggressively destructive molecules created by the effects of pollution such as smoking, pesticides, heavy metals, alcohol and they are also produced by many of the processes occurring inside our bodies. The immune system itself creates free radicals to use as a weapon against invaders.

A free radical is a molecule that has lost an electron, especially an oxygenated molecule. The objective of such a molecule is to get back its electron, and it will do that by oxidizing any molecules it comes across: oxidation is the removal of an electron from a substance. Oxidation can destroy cell molecules which is why the aging process occurs through the destruction of body cells through the effect of oxidation by free radicals. They can also destroy the Synovial fluid that lubricates the joints.

The molecules that can prevent this are caused antioxidants, and include some of the well known vitamins such as A, C and E, and also other substances such as Coenzyme Q10, fatty acids such as those in Omega 3 fish oils, beta carotene and the minerals zinc and copper are also effective at reducing the inflammation cause by free radical oxidation. These vitamins and minerals will not reduce the pain in your joints, but will relieve other symptoms such as the inflammation, and help the joint to recover.

Vitamin D is another that can help to cause arthritis and joint problems if you are deficient in it. Vitamin D deficiency is not uncommon, especially in those who live in northern climates where they do not get much sunlight. This vitamin helps to build cartilage and to maintain healthy bone density. Vitamin D is found in oily fish and eggs, but the majority of people suffer a deficiency, if only slight in many cases. Discount vitamin supplements containing all of these vitamins and minerals will help to maintain healthy joints. Vitamin A is available naturally from eggs yolks, oily fish and dairy products, and most people know that vitamin C is obtained from fresh fruit and vegetables, especially the highly colored foods that are also rich in other antioxidants such as anthocyanins and carotenoids.

Rich sources of vitamin E include nuts, seeds, vegetable oils and wheat germ. Taking Omega 3 oil supplements will not prevent arthritis, but will help to relieve the inflammation and hence the pain. However, in spite of all of this, the only vitamin that has been extensively tested on patients suffering from osteoarthritis has been vitamin E. It has been established that significant improvements in the condition of patients were achieved by administering from 400-600 International Units (I.U.) of vitamin E daily for two weeks.

Another substance that is a component of connective tissue and that can be taken to help rebuild what is lost in joint disease is hyaluronic acid. This chemical is found all over the body, and involved in the structure of many types of connective tissue, including the joints, the vitreous humor of the eyes and heart valves. In the joints it is rich in the Synovial fluid that lubricates the joints, and also found in cartilage.

Although hyaluronic acid is contained in chicken soup, it is obtained mainly from rooster combs, then treated to reduce its molecular size so that it can be absorbed. Anybody allergic to chicken should seek their doctor’s advice on taking hyaluronic acid as a supplement.

It is highly recommended that a vitamin supplement be taken by anybody suffering from any form of arthritis or joint disease, but it is glucosamine that appears the best treatment for long term success. Glucosamine is a very large molecule, and it is difficult to get it to the site of the problem. To get to the joint, the molecule has to pass through the capillaries, and very few glucosamine molecules can actually achieve that.

That is why the doses are so large, so that even if only a small percentage gets to the joint then that is enough to help rebuild cartilage. The antioxidants help to destroy the root cause of many forms of joint disease: the free radicals and anti-inflammatories can help relieve pain. However glucosamine and chondroitin not only relieve the pain, but also continue to work over time to repair the joint tissues. As with most supplements the body can only absorb so much glucosamine, only consume 500mg at a time but take it two to three times each day for best results.

Glucosamine is often provided in conjunction with MSM (Methylsulfonylmethane) that is a natural form of dietary sulfur. Sulfur is believed to be essential for healthy soft connective tissues, tendons and so on. Calcium, too, is a useful supplement to take since it help to recover the bone density, but keep in mind that vitamin D is essential for the uptake of calcium, so a vitamin D supplement will be required along with the calcium. Although calcium will not in itself help joint disease, it will help to main a good bone density that is more capable of withstanding the stresses of a reducing cartilage density.

There is therefore quite a wide variety of vitamins, minerals and other substances that can help to support healthy joint function, and also to help repair joint damage, and discount vitamins are the best way to tackle the problem of maintaining a good intake of those that are most effective, namely, glucosamine and chondroitin sulfate, vitamins A, C, D and E, and supplemental MSM, hyaluronic acid and calcium.

You do not need them all, but only testing will enable you to decide which work for you. You should also contact your physician before taking discount vitamin supplements if you have any other medical problems.

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Date: October 18, 2007 03:58 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Natural Vitamin and Herbal Alternatives For Joint Health

Joint tissue breaks down and arthritis sets in for a number of reasons, and there are several natural alternatives for joint health that can be use to prevent this and to treat affected joints.

Thyroid problems can slow down the production of adrenal hormones that are responsible for the production of cortisone and cosrtisol. These are anti-inflammatories, that when unavailable or in low supply can result in joint inflammation. If you suffer joint pain in the mornings that tends to improve as the day goes on, then it is likely that is the cause since adrenal activity can improve as the day progresses.

One of the main reasons for joint tissue breakdown is osteoarthritis whereby the cartilage wears down until it fails to provide the necessary protection against impact between the bones in a joint, or against the friction generated when two bones rub together. Injuries to joints can have the same effect, whereby an injury to a hip or knee can appear to clear up and then later the cartilage wears out sooner than expected. This can take several months or many years, depending on the severity and nature of the injury concerned.

Continual wear and tear can also cause joint tissue to break down. Athletes and other sportspersons often suffer twenty years or more after retirement from their sport due to the gradual wearing down of cartilage while they were active. Once they stop, this continues to a lesser extent until the cartilage is eventually worn away sufficiently for it to stop protecting the joint.

Problems with the auto-immune system can lead to rheumatoid arthritis and inflammation of the joints. This weakens them and can eventually completely destroy the tissue. In such cases the tissues in the joint tend to swell and become extremely painful. Gout can also damage joints, especially in the big toe. This is caused through a built up of needle sharp uric acid crystals. Another cause is a deficiency in sodium and potassium in the diet that are needed to help maintain calcium in solution. When these metals are in deficiency due, for example, to an adrenal problem or some other reason, calcium can deposit right in the joints, causing undue pain.

Calcium and vitamin D deficiencies are commonly associated with arthritis sufferers, and protein deficiencies are also believed to be a contributing factor of rheumatoid arthritis, and it is also true that degenerative arthritis can accompany rheumatoid arthritis. This occurs in almost 40% of cases, and diet and nutrition are now being recognized as a major cause of both types. Deficiencies in folic acid or its natural form of folate, vitamin E, zinc and selenium have all been associated with degeneration of joint tissue, so it makes sense that a supplement of these substances can help to avoid these conditions.

Standard medical treatment, however, is for the relief of pain and reduction of inflammation through the prescribing of non-steroidal anti-inflammatory drugs (NSAIDs). Typical NSAIDs are aspirin, ibuprofen and naproxen. Although it relieves pain, paracetamol is not an anti-iflammatory. An alternative to blocking the inflammatory reponse is to help to regenerate the damaged joint tissue.

However, reducing the inflammatory response to tissue damage does not address the underlying problem, but masks it. Not only that, but there are side effects associated with the use of NSAIDs. Excessive doses can create serious gastrointestinal problems, such as bleeding, ulcer perforation and even death is possible in severe cases. Anti-inflammatories cause gastric problems in up to 20% of cases

The newer Cox-2 inhibitors act on the enzyme that causes the inflammation within the joint, and while these can be very effective, they are still masking the underlying problem. Incidentally, the Cox-2 inhibitors should not be used with NSAIDs, and both increase the possibility of a myocardial infarction or heart attack. Also, if you are taking aspirin to reduce the risk of heart problems, you should be careful not to use other NSAIDs since they can interfere with the effects of the aspirin.

More effective in the long run is to treat the conditions with substances that deal with the cause of the problem. Vitamin C, for example, improves the lubrication effect of the Synovial fluid in the joints, and vitamin E is a strong antioxidant that can help to repair damaged tissue and improve the circulation within the joints. Joints have very low blood circulation levels, which is a problem when trying to direct drugs to the joint tissues. Vitamin C is also good for improving the integrity of connective tissue. Zinc, manganese and copper are also instrumental in developing strong connective tissue and helping to repair the damage done to the joints.

Horsetail is a commonly used herbal remedy that can be taken as a tea, tincture or in capsules. It is the richest natural herbal source of silicon, which is used by the body to form connective tissue and collagen. Damaged connective tissue is rapidly repaired by horsetail, and its strength and elasticity significantly improved. It is commonly used in the treatment of arthritis and osteoporosis.

Cat’s Claw is used for its beneficial effect on the immune system, and frequently used successfully to treat osteoarthritis and rheumatoid arthritis. However, this treatment is used more to help reduce the inflammatory effects of the condition than to effect a long lasting cure. Gotu Kola, also called Indian pennywort, is traditionally used for treating arthritis. The fresh leaves are effective in reducing the inflammation and pain, and help to improve the quality of life of arthritis sufferers. In Australia, it is referred to as ‘the arthritis herb’ and two leaves a day are said to be effective.

Another popular remedy is MSM (methylsulfonylmethane), although it is claimed to provide pain relief rather than a cure. Amino acids also seem to help, and L-cysteine helps promote collagen and connective tissue. It appears to work best when taken in combination with vitamin E and selenium that are powerful antioxidants. L-arginine has a similar effect in the reconstruction of joint tissue, again helping to repair damaged connective tissues.

There are therefore two approaches to treating both rheumatoid and osteoarthritis, one providing pain relief and reducing inflammation, and the other repairing the damage done to the joint tissues. Vitamins, minerals, trace minerals and herbal remedies are used in both, though it is better to use a combination that provides pain relief and also helps to regenerate strong connective tissues in the joints.

When using combinations of remedies it is important that possible interactions are understood, and you should always seek the advice of your physician when using non-prescription remedies of any kind.

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Date: April 25, 2007 03:30 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Do you experience muscle pain and inflammation?

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Date: April 04, 2007 09:38 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Hyaluronic Acid Double Strength 100mg – w/ Proline, Alpha Lipoic Acid & GrapeSeed extract.

Hyaluronic Acid has emerged as one of the most significant anti-aging supplements in the natural products industry. As a mucopolysaccharide that occurs naturally within the human body, the highest concentrations of Hyaluronic Acid are found in the skin, eyes, and articular cartilage. Hyaluronic acid works by absorbing water within the body, which in turn supports the formation of effectiveness of the gel-like matrix that protects healthy cell structures from dehydration and free radical damage. Ongoing studies continue to suggest that it may help support some of the body’s most vital functions.*

Strong, Healthy Joints

At birth and well into our youth, the human body produces ample amounts of Hyaluronic acid. These levels decline, however, based on our physical activity levels, dietary habits, and other hereditary and environmental factors. Hyaluronic acid is a key component of Synovial fluid and cartilage, and serves as one of the body’s most vital natural lubricants. Joint structures lack blood vessels, and there for relay on Hyaluronic acid to transport fluids and nutrients. Many structural and articular challenges have been traced back to insufficient Hyaluronic levels.

Wrinkles and Fine Lines

Healthy, wrinkle-free skin requires a constant supply of water. Without enough, dermal cells located deep below the skin’s surface can becomes deprived of the compounds they need, thus leaving the skin dry and dehydrated. Hyaluronic acid attracts and binds large amounts of water at the cellular level to ensure that the skin has everything it needs to remain smooth, elastic, and youthful-looking.

Wound Healing

Some published reports suggest that a child’s ability to produce abundant amounts of Hyaluronic acid may explain why they heal so quickly, often without permanent scarring. Because of the many roles it plays within the body’s connective and epidermal tissues, Hyaluronic acid is becoming more and more accepted as a way to help encourage the body’s natural wound-healing processes.

Vision and Eye Health

In addition to cartilage and Synovial fluid, the eyes contain some of the body’s highest concentrations of Hyaluronic acid. In fact, the vitreous humor (the Eye’s Core) is made up almost entirely of Hyaluronic acid. This gel-like structure absorbs shock, supports vision, and protects the retina from being damaged. It is believed that many common vision and ocular problems may be a result of poor Hyaluronic acid production during adulthood.*

Each Vcap contains 100mg of Hyaluronic acid, along with Alpha Lipoic Acid, standardized Grape Seed Extract, and pharmaceutical grade L-Proline for support. Compare Now’s 100mg formula to some 50mg formulas that do not include supporting antioxidants for the same price, and the choice is clear!

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Let Vitanet Help you Look, Feel and Live Healthier with Hyaluronic Acid

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Date: March 28, 2007 11:10 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Glucosamine Sulfate and Chondroitin Sulfate

Glucosamine Sulfate and Chondroitin Sulfate

Osteoarthritis is the most prevalent form of arthritis in the U.S., according to the Arthritis Foundation. One-third of all American adults have X-ray evidence of osteoarthritis of the hand, foot, knee, or hip. Osteoarthritis is responsible for more than 7 million physician visits per year and is second only to cardiovascular disease as the cause of chronic disability in adults. As Baby Boomers age, the number of people suffering from osteoarthritis is expected to rapidly increase in the next 10 years.

While osteoarthritis research ahs led to the development of promising new prescription and over-the-counter medications aimed at reducing pain, none has created the excitement of glucosamine sulfate (GS), which actually addresses the underlying joint destruction.

Q. What is osteoarthritis?

A. Osteoarthritis is a complex, metabolic disorder of the cartilage and bones of certain joints. However, to fully understand how osteoarthritis develops, we need to understand how joints work.

A joint is formed when two or more bones are brought together and held in place by muscles and tendons. Some joints have very little range of movement, such as the joints of the ribs, while others have much more range of movement. Hips, knees, elbows, writs, and thumbs are termed Synovial joints, and have the greatest range of movement and mobility of human joints. To allow such mobility, Synovial joints have a unique structure.

The bones that form Synovial joints are covered with cartilage. Tough fibrous tissue encloses the area between the bone ends and is called the joint capsule. The joint cavity within the capsule is lined with an inner membrane, called Synovial membrane. The membrane secretes Synovial fluid, a thick, slippery fluid that fills the small space around and between the two bones. This fluid contains many substances that lubricate the joint and ease movement.

The cartilage of Synovial joints serves two very important functions. First, it provides a remarkably smooth weight-bearing surface; Synovial joints move easily. Secondly, Synovial cartilage serves as a shock absorber, providing a soft, flexible foundation. Healthy cartilage absorbs the force of the energy, transmits the load to the bone, and distributes the mechanical stress created by joint movement.

Synovial joints function under almost continual mechanical stress. A joint’s ability to withstand or resist this stress is a reflection of its health. When the mechanical stress is too great or the joint’s ability to resist this stress is compromised, physical changes occur in the cartilage covering the bones.

Cartilage is a tough, elastic tissue, comprised mostly of water, collagen, and complex proteins called proteoglycans. In osteoarthritis, the cartilage starts to weaken, becomes frayed, and eventually breaks down. This exposes the bones of the joint, which then rub together. A gritty feeling and grinding sound may occur when an osteoarthritic joint is bent and flexed. As osteoarthritis progresses, bits of bone and cartilage often break off and float inside the joint space. The bones may enlarge, causing the joint to lose its normal shape. Tiny bone spurs may grow on the joints’ sides and edges. These physical changes in the diseased joint are responsible for progressive damage and continual pain.

People with osteoarthritis most frequently describe their pain as deep and aching. The pain not only is felt in the affected joint but may also be present in the surrounding and supporting muscles. Joint inflammation also may occur, increasing the already considerable discomfort. Joint stiffness is another unfortunate component of osteoarthritis. Exercising the joint most often results in increased pain; however, stiffness tends to follow periods of inactivity. Humid weather often makes all osteoarthritis symptoms worse. As the disease progresses, the pain may occur even when the joint is at rest, creating sleepless nights and miserable days.

Q. What causes osteoarthritis?

A. Osteoarthritis’ exact cause remains unknown. Researchers know aging doesn’t appear to cause osteoarthritis. Cartilage in people with the disease show many destructive changes not seen in older persons without the disease. However, certain conditions do seem to trigger osteoarthritis or make it worse.

Some families seem to have a lot of osteoarthritis, pointing to a genetic factor. This is most commonly seen in people who have osteoarthritis of the hands. Repeated trauma can contribute to osteoarthritis, too. Athletes, extremely active people, and individuals who have physically demanding jobs often develop the disease. Persons who have certain bone disorders are more prone to osteoarthritis due to the continuous, uneven stress in their hips and knees.

Obesity also is a risk factor for the disease. In overweight women, osteoarthritis of the knee is fairly common. Excess pounds also may have a direct metabolic effect on cartilage beyond the effects of increased joint stress. Obese people also often have m ore dense bones. Research has shown dense bones may provide less shock-absorbing function than thinner bones, allowing more direct trauma to the cartilage.

Q. Can osteoarthritis be prevented?

A. While there is currently no sure way to prevent osteoarthritis or slow its progression, some lifestyle changes may reduce or delay symptoms. The Arthritis Foundation states that maintaining a healthy weight, losing weight if needed, and regular exercise are effective osteoarthritis prevention measures.

Optimal calcium intake in younger years is vital to ensure a healthy aging skeletal system. Vitamins A, C, D, and E have been studied for their role in osteoarthritis prevention. These vitamins also have shown benefit in individuals who have osteoarthritis.

Q. What treatments are available for osteoarthritis?

A. The goal of treatment is to reduce or relieve pain, maintain or improve movement, and minimize any potential permanent disability. Typically, non-steroidal anti-inflammatory drugs or NSAIDs (pronounced “n-sayds”) such as aspirin and ibuprofen are used for pain and inflammation relief. These medications are effective in treating only the pain of osteoarthritis.

These medications have many side effects, some of which are serious. NSAID-induced gastrointestinal complications cause more than 100,000 hospitalizations and nearly 16,500 deaths annually in the U.S. Aspirin can cause an extremely annoying and continual ringing in the ears. NSAIDs frequently cause damage to the stomach lining, which can produce uncomfortable heartburn and abdominal pain. Continued NSAID use may lead to the development of stomach ulcers. NSAID-related ulcers can perforate the stomach lining and cause life-threatening bleeding. Most NSAIDs also interfere with blood clotting and may cause kidney damage. When older persons take NSAIDs, dizziness, drowsiness, memory loss, and decreased attention span may occur.

Acetaminophen (Tylenol and similar medications) is similar to aspirin and other NSAIDs in its pain-relief abilities. However, acetaminophen doesn’t reduce inflammation. And while acetaminophen doesn’t have the same side effects of aspirin and other NSAIDs, if large doses are taken, liver damage can occur.

Newer medications called COX-2 inhibitors provide both pain relief and reduce inflammation without the many side effects of acetaminophen, aspirin, and other NSAIDs. More recent research has indicated that, in certain situations. COX02 inhibitors also can cause stomach lining damage and bleeding. While aspirin, NSAIDs, and COX-2 inhibitors may reduce osteoarthritis pain, they do nothing to stop or slow down cartilage deterioration. In other words, these medications have no effect on the disease itself.

That is why many believe glucosamine sulfate (GS) and chondroitin sulfate (CS) are preferable to pain relievers and anti-inflammatory medications in osteoarthritis treatment: they actually improve Synovial joint health. And they do this without potentially life-threatening side effects.

Q. How do GS and CS work?

A. GS improves the health of joints affected by osteoarthritis. This supplement is so effective that even physicians who mostly rely on conventional medications routinely recommend it to their patients with osteoarthritis. In fact, GS is so good at treating osteoarthritis, many physicians use it for their own osteoarthritis joints.

There is even more good news. When glucosamine sulfate is combined with low-molecular weight CS, even greater benefits can be achieved. GS and CS are naturally occurring compounds found in human joints. The right GS/CS combination actually reverses damage in joints affected by osteoarthritis, in turn significantly reducing pain and stiffness.

Glucosamine occurs naturally in the body and is found in Synovial fluid. Glucosamine is a basic building block for proteoglycans, is a basic building block for proteoglycans, one of the important compounds of Synovial cartilage. It also is required for the formation of lubricants and protective agents for the joints.

In Europe, GS and CS have been used to treat osteoarthritis for more than 10 years. While persons with arthritis felt much better when they took GS and CS, no one really knew how these compounds worked. When European and American researchers first started to study glucosamine, they discovered GS can reduce Synovial joint inflammation. This explains why people felt better after taking it.

Q. What has additional study of GS and CS revealed?

A. As the scientific study of GS progressed, researchers determined it can stimulate the growth of cartilage cells, inhibit proteoglycans breakdown, and rebuild cartilage damaged from osteoarthritis. In other words, GS does not simply make persons with osteoarthritis feel better; GS actually makes persons with osteoarthritis get better.

GS is the form of glucosamine used in research. It’s the sulfate salt of glucosamine and breaks down into glucosamine and sulfate ions in the body. The sulfate part of GS plays an important role in proteoglycans synthesis.

CS also provides cartilage strength and resilience. CS is an important component of the cartilage proteoglycans of Synovial joints. Because CS helps the production of proteoglycans, researchers believe CS works in a similar nature to GS.

Q. Couldn’t GS and CS be taken on their own? Is there any benefit in taking them together?

A. Research has discovered GS and CS act synergistically (work well together) in improving joint health. Several studies have investigated this action and it’s recommended that GS and CD be taken together. However, there may be times when your healthcare practitioner may recommend using one or the other, but not both GS and CS together. Please follow their recommendations to obtain the best results for your own unique health concerns. Low-molecular weight chondroitin sulfate (CS) is the preferred CS form, and the form that has shown the most promise in studies.

Q. Why is it important to take low-molecular weight CS?

A. When CS was first studied, it was given to six healthy volunteers, six patients with rheumatoid arthritis, and six patients with osteoarthritis. Researchers then measured the levels of CS in all study subjects. They found no evidence of CS in any of the subjects. This single study led many physicians and scientists to believe CS can’t be absorbed, and was not an effective natural treatment.

However, several other studies in healthy volunteers have reported CS can be absorbed. The distinct difference for these findings is thought to be associated with the types of CS used in the studies. Some forms are much more absorbable that others. This was demonstrated in a recent study using CS with lower molecular weight. A higher absorption is observed for low-molecular weight CS.

This means CS products with a low molecular weight may be better absorbed, allowing the CS to get into the bloodstream and the Synovial fluid of joints where it’s needed.

Q. Are there other supplements that can help osteoarthritis?

A. Several vitamins, minerals, enzymes, and natural supplements have benefits for individuals with osteoarthritis. Proteolytic enzymes effectively offer relief of the pain, stiffness, and swelling of osteoarthritis.

Folic acid and vitamin B can reduce the number of tender joints and increase joint mobility. Vitamins C, D, and E not only may prevent osteoarthritis, but inhibit the disease’s progression. Niacinamide improves joint function, range of motion, and muscle strength. Clinical studies using the herb Boswellia serrata have yielded good results in osteoarthritis.

Application of ointments on osteoarthritic joints may be helpful in reducing pain and stiffness. Menthol-based preparations can provide soothing relief to painful joints. Capsaicin ointments and gel made for cayenne pepper also are very beneficial. When applied to the skin, capsaicin first stimulates, then blocks, nerve fibers that transmit pain messages. Capsaicin depletes nerve fibers of a neurotransmitter called substance P. This neurotransmitter transmits pain messages and activates inflammation in osteoarthritis. Capsaicin ointment is very effective in relieving osteoarthritis pain in many individuals.

Q. Is there anything else I can do for joint pain and stiffness?

A. When osteoarthritis occurs in the hands, use of a paraffin dip can be very comforting. A licensed health care practitioner can provide information about how to safely use paraffin dips at home.

Exercise is an excellent way to keep joints mobile, decrease pain, and increase body strength, too. Water aerobics also can reduce the pressure and stress on joints.

The Arthritis Foundation strongly suggests making movement an integral part of your life. When you’re in less pain and have more energy, more range-of-motion, and a better outlook on life, you’ll reduce stress and be a much healthier person despite your osteoarthritis.

One important last thought

When we don’t feel well, we sometimes have a tendency to self-diagnose. If you haven’t been evaluated by a licensed health care practitioner for your joint pain and stiffness, you need to do so. These symptoms may be caused by other illnesses and may require much different treatment. Only licensed health care practitioner can provide a certain diagnosis of osteoarthritis.

Conclusion

Osteoarthritis may be a part of life for many of us as we age; however, constant pain and stiffness need not be. GS combined with absorbable CS can actually improve damage in joints affected by osteoarthritis and significantly reduce pain and stiffness. And it can be an empowering way to improve your health.

Buy Glucosamine and Chondroitin Sulfate at Vitanet ®, LLC

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1500)

Date: December 11, 2006 03:46 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Benefits - Supports joint function and tissue health*

To understand glucosamine's role, it is important to understand joint structure and function. Cartilage in the joints acts as a shock absorber to cushion the blows of daily wear and tear. Joint cartilage is made of a unique connective tissue that consists of collagen and proteoglycans. Collagen is a strong, fibrous, insoluble protein. Proteoglycans are large, carbohydrate-rich protein chains made up of 95 percent polysaccharides and 5 percent protein called glycosaminoglycans (GAGs). GAGs are composed of repeating two-sugar units (disaccharides) that contain glucosamine sulfate and other amino sugars. Surrounding the joint cartilage is Synovial fluid, which contains many substances including its chief component, hyaluronic acid. Hyaluronic acid forms the backbone of other proteoglycans and is responsible for the thickness of Synovial fluid as well as its lubricating and shock-absorbing properties. Synovial fluid also provides nutrients for the joint cartilage.

Glucosamine sulfate is a normal constituent of glycosaminoglycans in cartilage and Synovial fluid. In essence, glucosamine sulfate provides important building blocks for cartilage production. Laboratory studies suggest that glucosamine may also function to stimulate production of cartilage-building proteins. It is also thought that the sulfate portion of the molecule contributes to the efficacy of glucosamine sulfate in the Synovial fluid by providing the elemental sulfur needed for strengthening cartilage and aiding glycosaminoglycan synthesis. 1,2,3

Glucosamine sulfate has been the subject of research for over twenty years. Clinical trials as well as experimental studies have repeatedly supported the efficacy of oral glucosamine sulfate in supporting joint function. In one large open trial, over 1200 people took oral glucosamine sulfate for periods ranging from 36 to 64 days. In this multi-center trial, ninety-five percent of the subjects experienced greater joint comfort and increased mobility. The physicians reported "good" results in 59%, and "sufficient" results in 36%. Furthermore, the improvements in joint health lasted for up to three months after the glucosamine sulfate was discontinued. 3

Promotes optimal joint comfort, function and flexibility*

Boswellia serrata (Indian frankincense) has been used for centuries in the Indian Ayurvedic system of medicine to maintain healthy joints. Even today, this is one of the primary uses for this plant in Ayurvedic medicine. Boswellic acids have been shown to support healthy joint tissue, maintain circulation to joints, enhance joint mobility, and promote joint comfort in animal models without known side effects. 4

Boswellin® is an extract rich in boswellic acids. Boswellic acids are potent modulators of enzymes involved in leukotriene synthesis in vitro, promoting a healthy balanced production of these components of the immune system.5 Healthy leukotriene balance can lead to enhanced joint function. A human clinical study was conducted to assess the effects of supplementation with a formula containing Boswellia, Curcumin and other nutrients on joint function. In this double-blind placebo-controlled crossover trial, participants were randomly assigned to receive the herbal formulation or a placebo for 3 months. Following this 3-month period, the treatments were reversed for an additional 3 months. The results showed that while each group was receiving the herbal formulation, they had superior joint function and a greater sense of joint comfort when compared to the placebo groups.6 Other trials lend further support to Boswellia’s ability to promote healthy joint function.4,6,7

Curcumin is a potent antioxidant that has known free radical scavenging activity. This activity of Curcumin is thought to play a major part in its role as a joint protective nutrient. In fact, the numerous beneficial effects attributed of whole turmeric are thought to stem in large measure from the antioxidant properties of curcuminoids. Antioxidants neutralize free radicals, which are highly unstable molecules that can damage cellular structures through abnormal oxidative reactions. Curcumin is not toxic to cells, even at high concentrations. Pure Curcumin was shown to be less protective than a mixture of curcuminoids, indicating a possible synergism among the curcuminoids.8

Curcumin demonstrates several other in vitro effects linked to free radical scavenging. Curcumin scavenges nitric oxide, a compound associated with the body’s inflammatory response.9 Curcumin also demonstrates in vitro inhibition of certain enzymes involved in promoting inflammatory reactions in the body. Together these results strongly suggest that Curcumin is a potent bioprotectant with a potentially wide range of therapeutic applications.9,10,11

Preliminary human trials have assessed the therapeutic potential of Curcumin, with results that verify the traditional use of turmeric as an herb to enhance joint health. In a short-term double-blind, cross-over, comparative study, eighteen people were randomized to receive Curcumin (1200 mg daily) or an alternative therapy for two-week periods. The participants in the Curcumin groups were shown to produce measurable enhancements in joint flexibility and walking time.12 Research suggests that Curcumin and Boswellia work extremely well in combination to benefit joint health and mobility, as trials combining both nutrients have yielded highly positive results.

Bioperine-Nature’s Absorption Enhancer Boosts Nutrient Absorption*

Traditional Ayurvedic herbal formulas often include black pepper or long pepper as synergistic herbs. The active ingredient in both black pepper and long pepper is the alkaloid, piperine. Experiments carried out to evaluate the scientific basis for the use of peppers have shown that piperine significantly enhances bioavailability when consumed with other substances.13 Several double-blind clinical studies have confirmed that Bioperine® increases absorption of nutrients.14

Curcumin is known to be poorly absorbed in the intestinal tract when used on its own, thereby limiting its therapeutic effectiveness. Oral doses are largely excreted in feces, and only trace amounts appear in the bloodstream. However, a study has shown that concomitant administration of 20 mg of piperine with 2 grams of Curcumin was able to enhance Curcumin bioavailability by an astounding 2000%. 15 These results speak to the wisdom of including a small amount of Bioperine® in the formulation to ensure nutrient bioavailability.

Sustained Release – For lasting joint comfort and convenient dosing

To ensure that the body can utilize all of the joint health-enhancing nutrients effectively, Best Joint Support featuring ArthriBlend-SR™ has been designed to have a sustained release delivery system. The nutrients are released over a longer period of time, maximizing absorption and providing the comfort-enhancing properties in a sustained manner. This unique delivery system allows the product to be taken just twice daily while maintaining its efficacy throughout the day.

Safety

Suggested Adult Use: Take two tablets every 12 hours. Take 4 tablets daily.

Scientific References
1. Vidal y Plana, R.R., Bizzarri, D., Rovati, A.L. Articular cartilage pharmacology: I. In vitro studies on glucosamine and non-steroidal antiinflammatory drugs. Pharmacological Research Communications 1978; 10(6):557-569.

2. Tapadinhas M.J., Rivera, I.C. Bignamini, A.A. Oral glucosamine sulphate in the management of arthrosis: report on a multi-centre open investigation in Portugal. Pharmatherpeutica 1982; 3(3):157-68.

3. Vaz, A.L. Double-blind clinical evaluation of the relative efficacy of ibuprofen and glucosamine sulphate in the management of osteoarthrosis of the knee in out-patients. Current Medical Research and Opinion 1982; 8(3):145-149.

4. Kimmatkar N, Thawani V, Hingorani L, Khiyani R. Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee--a randomized double blind placebo controlled trial. Phytomedicine. 2003 Jan;10(1):3-7.

5. Safayhi, H., Mack, T., Sabieraj, J., Anazodo, M.I., Subramanian, L.R., and Ammon, H.P.T. (1992) Boswellic acids: Novel, specific, nonredox inhibitors of 5-lipoxygenase. J. Pharmacol. Exp. Ther. 261(3), 1143-1146.

6. Boswellia serrata. Alternative Medicine Review Monographs – Volume One. 2002.

7. Kulkarni RR, Patki PS, Jog VP, Gandage SG, Patwardhan B. Treatment of osteoarthritis with a herbomineral formulation: a double-blind, placebo-controlled, cross-over study. J Ethnopharmacol. 1991 May-Jun;33(1-2):91-5.

8. Majeed, M., Badmaev, V., Shivakumar, U., Rajendran, R. Curcuminoids: Antioxidant Phytonutrients. 1995. Piscataway, NJ: NutriScience Publishers.

9. Snow, J.M. Herbal Monograph: Curcuma longa L. (Zingiberaceae). The Protocol Journal of Botanical Medicine, Autumn 1995:43-46.

10. Rao, S., Rao, M.N.A. Nitric oxide scavenging by curcuminoids. J Pharm. Pharmacol. 1997;49:105-7.

11. Ramsewak, R.S., DeWitt, D.L., Nair, M.G. Cytotoxicity, antioxidant, and anti-inflammatory activities of Curcumins I-III from Curcuma longa. Phytomedicine 2000;7(4):303-308.

12. Deodhar, S.D., Sethi, R. Srimal. R.C. Preliminary study on antirheumatic activity of curcumin (diferoyl methane). Indian J Med Res 1980;71:632-34.

13. Atal, C., Zutshi, U., Rao, P. Scientific evidence on the role of Ayurvedic herbals on bioavailability of drugs. Journal of Ethnopharmacology 1981;4:229-232.

14. Bioperine®–Nature's Bioavailability Enhancing Thermonutrient. Executive Summary. 1996; Sabinsa Corporation, Piscataway, N.J.

15. Shoba, G., et al. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Medica 1998;64(4):353-6.

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for Great Joint Health buy Best Joint Support at Vitanet

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Date: June 01, 2005 01:13 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Elan Vital - The Vital Essence of Life - Multi-Vitamin and Mineral Supplement

Elan Vital Multiple

What makes ÉLAN VITÀL unique is its unprecedented range of nutriments in high potencies and superior forms. Quite simply, it stands alone among multiples: a quantum leap beyond maintenance...into excellence. Not only does it offer unparalleled antioxidant nutrition and a full-spectrum of essential vitamins and minerals, ÉLAN VITÀL is also formulated with specific nutrients that support: