Search Term: " Build-Up "
Can Apple Cider Vinegar really help you lose weight?
February 19, 2019 07:53 AM
People have trusted apple cider vinegar to help them shed those unwanted pounds for many years now after a fly by night company brought claims of its benefit to lose weight. But, have we all been duped or can apple cider vinegar really help those pounds come off? In a test conducted using mice and rats, weight loss did occur when given apple cider vinegar. Scientist say that it is true and yu can lose weight when using this product!
"They reported that acetic acid could prevent the build-up of body fat and lipids in the animals."
Read more: https://www.naturalnews.com/2018-12-20-can-acv-really-help-you-lose-weight.html
Animal Study Finds Monounsaturated Fats in Olive Oil May Extend Life
June 10, 2017 12:14 PM
A recent genetic study on metabolic changes has discovered an unexpected finding: accumulation of monounsaturated fats may lengthen one's lifespan. Though the study was conducted among roundworms rather than humans, it is interesting to note since researchers previously thought that decreased caloric intake would increase longevity. Rather, it appears that this particular build-up of fat and calories can be beneficial. The researchers discovered this by blocking certain DNA-modifying proteins to increase lifespan among worms, and then noted that these worms displayed higher levels of monounsaturated fatty acids.
"Prior research shows the type of fat consumed has a much greater influence on health than the quantity, and the recent experiment builds upon what is known on the topic."
Read more: https://www.oliveoiltimes.com/olive-oil-health-news/animal-study-finds-monounsaturated-fats-olive-oil-may-extend-life/56292
7 Natural Home Remedies for Gout
January 27, 2017 07:54 AM
Gout is a form of proactive arthritis, a condition which affects the joints, caused by the Build-Up of uric acid crystals. So what can be done to get rid of gout? Well there are some natural home remedies that can help. Soak 1 Tbsp fenugreek seed in half cup water overnight and drink that water in the morning and chew the soaked seeds. Swallow one pod of garlic and if you find it difficult then you can finely chop the garlic and then consume it.
"Gout is also caused due to the consumption of more proteins and curd, so to avoid that one should lessen the intake of pulses or any other sources of protein and curd in your diet.”"
6 Fruits That Are Even Healthier Than You Think
December 28, 2016 02:59 PM
While apples and oranges are the usual go-to fruits for healthy eating, the wider variety of healthy fruits should not be ignored. Don't forget that avocados and black berries are choc full of vitamins! Vitamin C is plentiful across those and many other fruits: papyas, grapes, kiwis, and dragon fruits. The latter is also a good source of calcium, and some of these fruits can aid sleep or offer relief from cramps.
"They are also rich in fiber and antioxidants, and this together makes the papaya an effective fighter of cholesterol Build-Up in the arteries, which again works to prevent heart disease."
Clear heart blockages with this powerful lemon and garlic mixture
November 05, 2016 07:59 AM
You or someone you know has been or will be affected by problems with their cholesterol. This is one of the leading causes of heart blockages but some simple remedies could help clear the passages and give you a more life to live, if you aren't a vampire!
"If you are one of the millions of people struggling with high cholesterol levels, regular exercise, eating a heart-healthy diet and losing weight are all it takes to lower them."
Herbs that Support Healthy Vision
May 21, 2012 08:02 AM
The overall health of the eyes is essential to help retain a healthy vision and vision is considered to be one of the greatest assets of the total body health. Healthy vision is important to lead a good life. As the whole body needs exercise, eyes also need exercise regularly. To maintain optimum vision health it is necessary to provide proper nutrients to the eyes. Natural herbs help prevent vision loss and antioxidants are good for aging eyes.
Here are a few herbs that support a healthy vision:
Eyebright (Euphrasia Officinalis)
Eyebright grows wild throughout Bulgaria, Hungary and the Balkans. This herb is grown in Europe for commercial purposes. Eyebright is rich in vitamins A, B, C, D and E, iridoid glycosides, flavonoids and tannins. This herb is used to fro relieving eye problems such as eye strain, pink eye and inflamed, sore and irritated eyes. The common name, "Eyebright," is derived from its use as a nutritional support to the eyes. Eyebright is used in making external poultices, teas, tinctures, fluid extracts and the whole herb is used for dietary use.
Bilberry is a close cousin to blueberry and has been widely used in Europe for eye health. Bilberry is the world's most famous herb that supports healthy vision. Bilberry helps blood to flow easily to the eye nerves. It has an antioxidant called anthocyanins, which protects the delicate eye tissues and protects the eye from the harmful UV rays from the sun. The other nutrients present in bilberry nourish the eye for a clear vision and light adjustment.
Goji berries contain anthocyanins, the antioxidants which help prevent age related damage and improves blood flow in the eyes.
Wolfberry is a Chinese herb with potent medicinal properties to strengthen the eyesight. Wolfberry has been in use in China, for centuries, to protect the eye and to promote good vision.
Red Raspberry is a native European herb that is used to treat sore eyes. Their leaves are rich in vitamin C and are high in tannin content. This herb is used as eyewash for discharge.
Grape seed is an important source of nature's most potent antioxidants - proanthocyanidins that are anti-inflammatory, antihistamine and antiallergenic, and they also act as free radical scavengers. Grape seeds helps vitamin C enter the body cells.
Chrysanthemum flowers help reduce pressure Build-Up in the eye. Steep chrysanthemum flowers in hot water, drink the beverage or use it to wash eyes in eye-wash cups.
Peppermint is an antioxidant which can clear vision.
Ginkgo Biloba improves blood flow in the eyes. People with diabetes will have blood circulation problems and increased blood clotting tendencies. The small clots in the retinal area of the eye leads to poor vision. Ginkgo Biloba reduces the blood clots, increases blood flow and makes the red blood cells more flexible. The flexible red blood cells squeeze through the tiny blood vessels and help to carry more oxygen to tissues and cells.
Herbal treatment for a healthy vision is the best natural way to improve eyesight.
The Major Health Benefits Of Hemp
April 06, 2012 07:47 AM
Hemp is the only food with the largest amount of protein available on earth. It is easily digestible and it is the only food with a wide range of proteins. These include important fatty acids and amino acids. It is the only food that supplies the human body with all dietary needs at once. Thus, it is the only food that is capable of sustaining human life alone without other nutritional supplements.
Apart from being a good source of proteins, hemp supplies the body with important minerals and vitamins. However, the most important component of this food is the essential fatty acids. These include the alpha-linolenic (omega 3) and linoleic acids (omega 6). These two categories of fat are important in the body because human body is not capable of manufacturing them. Therefore, they have to be consumed in the daily meals. The ratio of omega 6 to omega 3 in hemp is 3:1. This is close to the 4.0 on average as the optimum recommendation of the world health organization for a human diet.
It plays an important role in various organs of the body including:
Hemp has important nutrients are that are essential for the good health of the human heart. These are the essential fatty acids which play a very important role in ensuring the health of the heart. Several studies have revealed that substituting saturated fats with healthy polyunsaturated reduced risk of cardiac arrest. Such fats are found in hemp and are important in preventing sudden cardiac arrhythmia. They also reduce levels of cholesterol in the blood. Hemp has important fats that also decrease Build-Up of cellular in the arteries. This is very important as it is associated with a condition known as atherosclerosis. Phytosterol contained in hemp plays an important role in reducing cholesterol in the blood by about ten percent.
Human brain has a large portion that includes essential fat acids. Since hemp supplies the body with these fats, it becomes essential for brain health. It is also vital for proper memory function. Diseases such as Parkinson's and Alzheimer's are preventable with consumption of hemp. The Omega 3 and omega 6 fatty acids also help in delaying or reducing neurological effects that come with these diseases. This improves the kind of life led by individuals with such diseases.
Essential fatty acids play an important role in ensuring healthy skin. Perhaps, this is why hemp seed has been used as an ingredient in various cosmetic products. The Lipids allow the acids to permeate via the skin. Hemp component in the cosmetic products help to nourish the skin directly. Hemp is also very beneficial to people with psoriasis and eczema skin conditions.
These are just the major benefits of hemp in the human body. Others include increasing of metabolic rate and energy levels, improving immunity and organic function, among others. Hemp is also crucial in the prevention of degenerative diseases and this proves why it is crucial for positive human health. This food provides a lasting solution to various health complications and you may as well try it and enjoy its benefits.
Serrapeptidase: Natural NSAID
March 27, 2012 03:26 PM
Serrapeptase, also known as Serratia peptidase is a proteolytic (protein-splitting) bioactive enzyme found in the intestines of the silk worm. This silk-worm enzyme is widely used in Europe and Japan in clinical therapy for relieving pain and inflammation. When the silk worm leaves the cocoon, it regurgitates the serrapeptase in to create a hole in the cocoon for its escape. It was soon discovered that serrapeptase enzyme has a unique property to dissolve dead material consisting protein without even harming the living tissue. This property of dissolving dead tissue can be used in treating many health conditions.
How Serrapeptase work?
Protein is the main component of most of the fibrous materials in the body. Once these fibrous materials out-live their purpose or are over-grown, they start causing serious disease conditions involving fibrosis. Fibrosis is an abnormal thickening and scarring of connective tissue caused by infection, injury, surgery or lack of oxygen. Serrapeptase works as an anti-fibrotic and helps in relieving the conditions in connective tissue scarring and thickening has occurred.
Health Benefits of Serrapeptase:
This proteolytic enzyme is considered an alternative to NSAIDS (Non Steroidal Anti-Inflammatory Drugs) that are used to treat osteoarthritis, rheumatoid arthritis and other inflammatory conditions. Serrapeptase has been used to treat fibromyalgia, colitis, Inflammatory Bowel Diseases, varicose veins, ovarian cysts, ear and throat infections, enlarged prostate and postoperative inflammation. Studies have shown its effective results in prevention and removal of arterial plaque.
Serrapeptase in relieving Pain:
Pain and Inflammation Reduction:
Serrapeptase is a great anti-inflammatory and analgesic agent. It reduces the inflammation and gives relief from the pain. It works by blocking the release of pain inducing amines from the inflamed tissues. Due to its pain relieving and anti-inflammatory properties, serrapeptase is used in treatment as an alternative to NSAIDS. This enzyme gives relief from mild to moderate pain like headache and backaches. Hence it is used all the inflammatory conditions such as colitis, sinusitis, arthritis and many more.
Serrapeptidase has an anti-fibrotic and fibrinolytic action that prevents and treats the accumulation of plaque in the arteries. Plaque is the accumulated deposits of cholesterol, fatty substances, cellular waste products, fibrin and calcium. Excessive plaque formation impairs the normal blood flow and cause partial or complete blockage, which also results in arteriosclerosis. Serrapeptidase helps to prevent Build-Up of plaque in the body. Due to its fibrinolytic action, it also helps in dissolving of proteins and breaking down atherosclerotic plaques. The dissolved deposits are eliminated from the body.
Hence, serrapeptidase prevents coronary artery diseases and improves cardiovascular health.
Due to its anti-inflammatory and mucus dissolving properties, Serrapeptidase is very beneficial for chronic sinusitis sufferers. Serrapeptidase helps in thinning and expelling the thickened mucus secretion present in nasal cavities of sinusitis sufferer.
Serrapeptidase helps in reducing the recovery time in any injuries, wounds or surgery. It promotes healing in post-operative wounds by reducing the inflammation and pain.
Serrapeptidase is available in the form of supplements. If you are taking NSAIDS for any healthy condition, substitute it with serrapeptidase supplement
Why Is The Amino Acid Tyrosine So Good for the Brain?
June 18, 2011 12:20 PM
Tyrosine is an amino acid that serves as an immediate precursor to several organic compounds found in the brain and the central nervous system. It is one of the 20 amino acids utilized by cells in protein synthesis. As such, it is an important component of the human diet, albeit not classified as an essential nutrient. Mental infirmities not related to age has been linked to tyrosine deficiency.
There is no daily value for tyrosine, but it is an integral part of proteins obtained from both animals and plants. Also, supplementation of tyrosine has not shown any adverse effects. That being said, deficiency in tyrosine is not unheard of. In fact, there is a rare autosomal recessive disorder called phenylketonuria that interferes with the synthesis of tyrosine and leads to brain damage and seizures.
Prevents Brain Damage
Tyrosine is one of the amino acids necessary for the manufacture of neurotransmitters and proteins that display vital functions in the nervous system. In phenylketonuria, the synthesis of tyrosine from phenylalanine is impaired, causing the Build-Up of the latter. High concentrations of phenylalanine deprive the brain of other amino acids, such as tyrosine. This results in progressive mental retardation.
The presence of tyrosine in the central nervous system is very important in mental development. It works as nutrient for nerve cells that powers neuronal activities. Not surprisingly, regular intake of tyrosine has been observed to display cerebroprotective properties. It has also been linked to the prevention of headaches following an intense physical activity.
Improves Stress Tolerance
It has long been suggested that supplementation of tyrosine may improve stress tolerance, but studies that support this claim have surfaced only recently. High levels of tyrosine in the brain appear to improve physiological responses to stress in both animal and human studies. Many researchers believe that depleting levels of tyrosine in times of stress contribute to mental fatigue.
Tyrosine is a precursor to catecholamines, organic compounds that function as neurotransmitters and hormones. It is converted to epinephrine, or adrenaline, which is responsible for the activities in the peripheral nervous system during stress. It is also converted to norepinephrine, which sends signals to both sides of the brain and forms a neurotransmitter system within the brain and the spinal cord.
Promotes Mental Clarity
Tyrosine plays a role in sustaining mental clarity, the reason why it is thought to produce nootropic effects. For one, the availability of tyrosine in the brain improves mental function, especially under psychological stress. It is utilized by the brain in the manufacture of brain chemicals involved in cognitive function and even motor skills.
More importantly, tyrosine provides a ready pool of levodopa, which increases dopamine levels. Both tyrosine and dopamine levels have been observed to be low in individuals suffering from clinical depression, suggesting that tyrosine may provide mood-altering effects. Since there is no harm in regular intake of tyrosine, it has been promoted as an alternative to other mood enhancers.
Policosanol, Cholesterol and how its tied together
January 27, 2011 10:44 AM
Cholesterol is a fatty substance that is essential to your health! If that sounds contrary to what you have been hearing about cholesterol, then you don't have all the information. Cholesterol is essential for the synthesis of hormones in your body, including the steroidal hormones such as the sex hormones and those that regulate your blood sugar. So you cannot afford to eliminate all cholesterol. However, you can reduce it, and you can also take steps to reduce the problems that cholesterol can cause.
You have likely heard of LDL (bad) and HDL (good) cholesterol - there is no such thing as bad or good cholesterol. Without 'bad' cholesterol you would not be alive! However, cholesterol is not soluble in water, so cannot pass round your bloodstream by itself. LDL stands for Low Density Lipid, which is a fatty substance that can attach to cholesterol and act as a type of ferry, to carry it around your blood.
The problem is that LDL is easily oxidized by the free radicals formed by your metabolism and breathing in traffic and industrial emissions. This causes it to release the cholesterol that then sinks and deposits as a plaque on the inside of your arteries, eventually blocking them and causing strokes and heart attacks. The HDL cholesterol is responsible for carrying the unused cholesterol back to your liver, so does not block your arteries.
Policosanol can reduce the amount of LDL cholesterol while still maintaining sufficient for your needs. It can also increase the HDL cholesterol: if more High Density Lipids that are not oxidized are available, then more cholesterol can be carried by them, and also possibly reduce the plaque Build-Up. This is what policosanol does: it reduces LDL and increases HDL cholesterol.
July 20, 2009 11:51 AM
Valerian was used by ancient Greeks for digestion, nausea, and urinary tract disorders. A famous Greek physician, Galen, was known for prescribing valerian to be used as a decongestant. Herbalist John Gerard recommended valerian for chest congestion, convulsions, and bruises in 1597. Additionally, Native Americans traditionally used valerian for healing wounds. It was also accepted as a tranquilizer from 1820 to 1942 and was listed this way until 1950.
One of the most valuable properties of valerian is its ability to produce a deep, satisfying sleep. This herb acts as a relaxant and is an effective remedy for fighting against insomnia. The active ingredients that are found in valerian root are also responsible for relaxing smooth muscle tissue and also depressing the central nervous system. It seems as if there is no single component of valerian that is entirely responsible for all of its sedative activity. Instead, several of the constituents of valerian are responsible for causing the sedative effect when combined together. Like other standard sleep aids that are often prescribed, valerian works in the same way. However, it possesses an advantage in the fact that it does not cause the morning grogginess that is often linked to prescription sleep medications.
There have been many different studies conducted which have all led to the belief that valerian possesses benefits for insomnia, anxiety, and stress. Valerian is also extremely useful for all kinds f sleep disorders, especially when those sleep disorders are related to anxiety, nervousness, headache pain, or even physical and mental exhaustion. Research has proven that valerian is not only effective in treating insomnia, but also in reducing sleep latency and night awakenings.
Valerian has been shown to be great for the heart, lungs, liver, stomach, and the nerves and the brain. It has also shown possibilities in helping with epilepsy, hysteria, migraines, and the elimination of worms. It does all of these things because it works to calm anxiety, muscle spasms, and nervous tension. In addition to the ability to relax and calm, valerian can help to improve mental acuity and coordination. One study even found that those individuals who were hyperactive were able to concentrate for longer periods of time with the assistance of valerian.
Valerian is rich in calcium, which gives it to the ability to strengthen the spine, nerves, and brain. This herb is also high in magnesium and manganese. Both of these minerals work with calcium in order to build healthy bones and nervous system. Valerian is high in selenium, which strengthens the body against immune related disorders. The niacin content that is found in valerian helps to prevent cholesterol Build-Up, irritability, depression, loss of memory, and weakness. This herb also contains potassium, iron, sodium, zinc, silicon, and vitamins A and C. There appear to be no contraindications to the use of valerian during pregnancy or lactation. Valerian is thought to be safe for almost everyone. Although safe, this herb is usually recommended for short-term use.
Great herbs like valerian are available in capsule, tablet, and liquid extract forms at your local or internet health food store. For more information about valerian and its benefits, contact your local health food retailer. Always purchase name brands to ensure quality and purity of the valerian product you purchase.
*Statements contained herein have not been evaluated by the Food and Drug Administration. Natural herbs are not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.
May 02, 2009 11:41 AM
Methionine is an essential amino acid, meaning that it is not synthesized by the body, and so has to be taken as part of your diet. It also contains sulfur, one of two sulfur-containing amino acids that can form proteins, the other being cysteine. It is a precursor for taurine, which is an aminosulphonic acid, and not strictly an amino acid, which together with cysteine supports the health of your cardiovascular system and helps to eliminate toxins from the body.
Maintenance of Cell Membranes
It is also an important intermediary in the maintenance of cell membranes. Phospholipids are fat-soluble components of the cell membrane, phosphatidylcholine being a very important example. Also known as lecithin, this substance is derived from choline, itself biosynthesized in a chemical pathway involving S-adenosylmethionine.
This substance is made in the body from ATP (adenosine triphosphate) and methionine with the help of the enzyme methionine adensosyltransferase. Known as SAM (or SAM-e), S-adenosylmethionine employs a number of metabolic pathways in its reaction, though generally aminopropylation, transmethylation and transsulfuration. These add aminopropyl, sulfo and methyl groups to a number of substances, the most common being the methylation of proteins, nucleic acids and lipids.
Phosphatidylcholine is produced by the enzyme-catalyzed sequential methylation of phosphatidylethanolamine, SAM donating the methyl groups. The maintenance of the integrity of the cellular membrane by phosphatidylcholine is critical to all of the basic processes in human biology, including communication between cells, flow of information and bioenergetics.
A by-product of this reaction is homocysteine, formed in the liver from the S-adenosylhomocysteine that SAM is changed to after donating methyl groups. Excess homocysteine in the blood can create the risk of myocardial infarction and cardiovascular disease. SAM is also of use in the treatment of depression and of arthritis.
Creatine is a substance well known to athletes as being useful in provide short-term energy for high-intensity training. Although available in the diet, about 50% creatine used by the body is biosynthesized from methionine and two other amino acids, glycine and arginine. It allows a burst of energy lasting about 10 seconds, carried out without the use of glycogen reserves or fatty tissue.
Glycine and arginine combine to release ornithine as a by-product, and form guanidino acetate. SAM donates a methyl group to the latter to form creatine, about 95% of which is then stored in the skeletal muscle tissue. The stored creatine phosphate has the effect of allowing the muscle cells to hold more water, which also enables an enhanced level of protein synthesis, and hence an increase in muscle bulk, which also results from the increased blood flow resulting from the short-term high-intensity exercise that creatine allows.
Creatine can also increase the levels of MRF4 (myogenic transcription factor), resulting in an increasing in the myonuclei provided by satellite cells to damaged muscle tissue, that not only repair damaged muscle fibers, but also increase their ability to grow.
Detoxification of the Liver
Substances that help the liver to process fats, or lipids, are known as lipotropic, and the important lipotropics in human biochemistry are imositol, betaine, choline and methionine. They prevent fat from accumulating in the liver, and methionine is also useful in its effect of glutathione. This is a substance that helps the liver to neutralize toxins, such as excessive doses of acetaminophen, and its supplies are regulated by methionine.
Methionine and Autism
Research into autism is closely studying the Methionine/Glutathione Transsulfuration Pathway. This pathway is a very important biochemical means of detoxification, whereby toxins are methylated and then excreted. This pathway seems to be disrupted in autistic individuals.
Not only that, but disruption can lead to oxidative stress which results in many health problems. An example of this is the Build-Up of the oxidant homocysteine when there is insufficient Vitamin B6 to convert it into cysteine. This has been discussed previously, and is discussed again below.
Although research is in its infancy, it appears that AIDS sufferers also have decreased levels of methionine in their blood. It is believed that the process of AIDS could be linked to this, particularly the dementia that can occur as a result of the deterioration of the nervous system.
It is also hoped that it can help with some symptoms of Parkinson's disease, and pancreatitis. Initial research into this use of methionine has been very promising, as are studies into its use for urinary tract infections. It appears to operate like cranberry in this respect, preventing bacteria from attaching to the cell walls and multiplying in the urinary tract.
Methionine is believed to be essential for the formation of collagen, and for healthy pliable skin, hair, nails and other forms of connective tissue. For this reason it is often used as a supplement for the treatment of arthritis, although an excess should be avoided for reasons discussed above. S-Adenosylmethionine generates homocysteine during the biosynthesis of phosphatidylcholine, and this can cause cardiovascular problems.
So stick to the recommended doses when you use methionine as a supplement. Used properly, and according to instructions, it offers many health benefits, and can also be used to bulk up your muscle tissue and give increased energy when you need it most.
Dietary sources include fish, eggs, lentils, onions, garlic, meat, seeds, spinach and yoghurt. A good supplement would be from 800mg - 1000mg per day, and is best taken along with a B vitamin complex, or at least folic acid and vitamins B6 and B12, in order to prevent the increased generation of homocysteine.
Methionine also promotes the excretion of estrogen, so is a possible supplement for women on oral contraceptives that lower the production of this hormone. The elderly might also benefit from a supplement although, if taken for any specific condition, your health professional should be consulted first, as they should be for any supplement.
Nevertheless, methionine is a very useful supplement, and can be taken to prevent a large number of conditions. Research is continuing on its effect on AIDS patients, and Parkinson's, and it is hopeful that it will one day be recommended to help people suffering from these conditions.
Strengthen The Liver and Kidneys With Leucine
April 27, 2009 02:08 PM
L-leucine is an amino acid that is used by the body to fuel exercise and muscle-building to provide you with that athletic edge that gets you ahead of your opponents. It does so in a number of ways, none of them specifically by the direct generation of energy as such.
It is also an essential amino acid, since it cannot be manufactured by your body and hence must be taken as a supplement or as part of your diet. Foods rich in leucine include nuts, whole wheat products such as wholemeal bread, and brown rice. It is a hydrophobic amino acid, meaning that it does not like water.
It is also one of three essential branched chain amino acids, the other two being L-valine and L-isoleucine, and offers many benefits to athletic performance that shall be discussed below It also helps to preserve the body's stores of glycogen, used as an emergency energy source. Other than these properties, it possesses others, such as the maintenance of the nitrogen balance in the body.
So how does it work to fuel your body while you are exercising? The answer is not as you might think. L-leucine doesn't increase your energy levels as creatine does when it elevates your ATP (adenosine triphosphate) levels. ATP is the molecule of energy that is synthesized in your body cells, and is then converted back to ADP, the diphosphate, with the release of energy in the form of muscular contractions.
This amino acid is what is referred to as a 'limiting' substance, in that the other amino acids cannot do their jobs in your body unless you have sufficient L-leucine in proportion to them. Specifically, you need two parts of L-valine and two parts of L-leucine to one part of L-isoleucine for optimum usage of the food that you eat.
Therefore you cannot just take the supplement without considering how much should be taken to ensure this balance. Excess will be wasted and a deficiency would fail to make proper use of the protein content of your food.
If you suffer from a deficiency, therefore, your body cannot make best use of the protein in your diet to the extent that muscle tissue will not be generated during exercise. In fact it causes catabolism, or the breakdown of muscle tissue, resulting in a loss of performance and possible increase in fatty tissue as opposed to lean muscle. The only way to build muscle is take in sufficient nitrogen in the form of amino acids and protein, along with L-leucine to put that protein to best use.
One of the major properties of L-leucine is in stimulating the synthesis of skeletal muscle tissue and by using a supplement, the protein balance can be positive after a workout. It has been shown that this protein balance is generally negative until specifically L-leucine is consumed.
The way it works is to activate a muscle-generating pathway known as mTOR (mammalian Target of Rapamycin). mTOR is normally activated when the levels of ATP in the muscle cells is high, and when these levels drop then mTOR is deactivated. The activity of mTOR is sensitive to the concentration of L-leucine, and when the concentration of the amino acid in the body rises it informs mTOR that the protein in the diet is sufficient to manufacture skeletal muscle tissue, and so mTOR s activated.
Exactly how this is done is unknown, but is a fact the mTOR depends upon both L-leucine concentration and also ATP levels. This amino acid also decreases catabolism through a number of different mechanisms, one of which involves increasing insulin levels.
In fact, when insulin and L-leucine levels increase at the same time, there is a synergy that promotes the synthesis of new protein. Not only that, but the response of insulin to the presence of carbohydrates is enhanced, this resulting in an enhancement of your body's metabolism.
The amino acid can also be used to help those suffering from kidney and liver problems because it increases liver protein synthesis. It is therefore a useful adjunct both to diabetics and those suffering from liver and kidney disease.
However, because L-leucine is an essential amino acid with so many important properties, a deficiency can have specific consequences. Catabolism has been stated earlier as one such reaction to a deficiency, and others include decreased energy levels and irregularities in the levels of blood sugar.
Everything about this substance is not good however, and when taken by itself in excess, it can reduce the amount of the other amino acids in the blood, particularly of the other two branched chain amino acids (BCAAs). This in turn upsets the balance of amino acids, and reduces further the ability of the body to produce muscle tissue until a balanced supplement is taken.
Leucine also helps to maintain the nitrogen balance. It is essential for the human body to maintain a positive nitrogen balance, and L-leucine supports this. In fact, one study has demonstrated that after 12 hours infusion with L-leucine, nitrogen balance was improved by as much as 23%.
A supplement alone is not always sufficient to maintain a positive nitrogen balance. It is generally essential that you rest your body for a sufficient length of time to allow protein to be generated. If you don't take the required amount of rest, a surplus of protein could be used to maintain energy levels rather than replace lost protein and maintain a good nitrogen balance.
A positive nitrogen balance is essential for the generation of muscle tissue, such as in bodybuilding for example, since all proteins contain nitrogen and the net nitrogen intake must exceed the excretion rate. Not in gaseous form, of course, but in the intake of amino acids and proteins. The more positive your nitrogen balance is, the faster you will recover after exercise. It is essential for anabolic exercise.
L-leucine, therefore, is a supplement that can help to maintain your current muscle mass while undergoing strenuous exercise, in addition to increasing it while resting. It offers other health benefits, one being helping to maintain clarity of thought in the aged. However, it is for its effect on muscular Build-Up and the athletic edge that provides that the supplement is most commonly taken.
L-Alanine Non Essential Amino Acid
January 05, 2009 04:31 PM
L-Alanine is one of 20 amino acids that are used by the body to manufacture the proteins essential for life. Each protein possesses specific biological properties that are imparted by the sequence of amino acids it contains. Proteins control the chemistry that takes place within the cells of our body, and comprise all of the enzymes that catalyze the body's biochemistry.
Amino acids are also the building blocks of DNA that determines the genetic make-up of individuals, and that also provides recipes or templates for the production of proteins from amino acid sequences. There is a different DNA template for every protein required by the body that determines which of the 20 amino acids are needed, and in what order they are to be combined with one another to manufacture the desired protein.
10 of these 20 amino acids can be synthesized by your body's biochemistry, the other 10 being essential parts of your diet. If you fail to include just of these 10, then your body will break down its proteins until it has obtained a sufficient supply of that amino acids for its needs. That involves muscle and other tissue degradation, and is one of the symptoms of malnutrition. Amino acids are not stored, and a daily supply is essential to avoid these symptoms.
L-Alanine is one of the ten that the body can manufacture, and used by the body to help build protein and also to enable the body to make use of glucose to generate energy. It does so as part of what is known as the glucose-alanine cycle. During anaerobic exercise, such as in weightlifting and sustained running, muscles produce lactate and also alanine.
The alanine is passed on to the liver where it is converted to energy via its conversion to glucose. This is not a particularly efficient means of creating energy because a byproduct of the process is urea, the removal of which in turn requires energy. However, it serves its purpose as an energy source once the liver is depleted of glycogen. In fact that is the major use to which alanine appears to be put by the body: the conversion of glucose to energy.
The way the glucose-alanine cycle works is that a process known as transamination produces glutamate from the amino groups of amino acids that are degraded during exercise. Glutamate is then converted to pyruvate by means of the enzyme alanine aminotransferase, with the production of alanine and alpha-ketoglutarate. This is a reversible reaction, and after the alanine has been carried by the bloodstream to the liver, the reaction reverses with the regeneration of pyruvate that undergoes gluconeogenesis (generation of glucose).
The result of this is glucose that returns to the muscle tissue to provide more energy. The glutamate is broken down to the ammonium ion in the mitochondria, which in turn enters the urea cycle with the production of urea.
In a nutshell, then, the glucose-alanine cycle removes glutamate and pyruvate from muscle tissue to the liver where glucose is generated from the pyruvate and returned to the muscle. Since gluconeogenesis involves the expenditure of energy, and this occurs in the liver rather than in the muscle, all the energy in the muscle can be used for muscle contraction.
L-Alanine possesses other properties, among them the ability to help maintain the health of the prostate. A study of benign prostatic hyperplasia (enlarged prostate) indicated that treatment with L-alanine, glutamic acid and glycine over a period of three months reduced the symptoms. However, make sure that you consult your physician before using alanine in this way. This is not because there are any known adverse side effects, because there are not, but because it I always wise to so with any supplement taken with a view to treating any medical condition.
A less obvious application derives from the fact that it forms a stable free radical when deaminated. Deamination can be initiated by radiation, and so the concentration of this free radical can be measured to ensure that the correct dose of radiation is being given in dosimetric radiotherapy. It is not always easy to control the dose accurately, and this property of alanine allows it to monitored and to ensure that it is neither too low to have the desired effect, nor dangerously high.
Although it is a non-essential amino acid, and can be produced by the body, a dietary supply or supplement is advantageous if extra energy is required. Good dietary sources of L-alanine include meats, seafood, eggs, nuts, beans, seeds, brewer's yeast, corn and legumes among others. Supplements are also available, and useful for body-builders, weightlifters and others involved in anaerobic exercise. Due to the glucose-alanine cycle, it can possibly provide energy when lactate Build-Up would otherwise lead to muscle cramps.
Those for whom a supplement could be useful are athletes and others who are trying to build muscle and stamina, or reduce their body fat and also the obese and overweight for the same reason. There is also evidence that a combination of the amino acids alanine, glycine and arginine can help to reduce arterial plaque from oxidized low density lipoproteins, and can also help to reduce high blood pressure.
Deficiencies are rare, although groups that do not eat meat should be careful to eat foods with a good alanine content. There are no known side effects of a deficiency since the body will generate what is needed for normal purposes, and while the supplement appears to have no side effects, it is advisable that pregnant and lactating women should first seek medical advice. The same applies if you suffer from hypertension or diabetes. High doses of alanine might also affect those with kidney or liver disease.
Although the benefits of supplementation of L-alanine might not be immediately obvious, the results and the science indicate that it is effective in making better use of blood glucose in that the adenosine triphosphate (ATP) created in the muscle tissue is allowed to be expended on muscle contraction while the glucose-alanine cycle provides the energy needed for gluconeogenesis.
Essential Fatty Acids
July 24, 2008 11:19 AM
A balance in essential fatty acids is crucial for many bodily functions. It promotes good overall health as well. Particularly, omega-3 fatty acids are essential for human development and achieving good health throughout life. The tissues of the body require omega-3 and omega-6 fatty acids in order to function properly. There are many conditions that are improved by supplementing with omega-3 oils including high cholesterol levels, prevention of strokes, cancer prevention/treatment, psoriasis and eczema, heart disease, high blood pressure, multiple sclerosis, and rheumatoid arthritis.
Diets that are high in saturated fat are often linked with high blood-cholesterol levels, which is a risk factor for cardiovascular disease such as coronary heart disease and stroke. Many diet therapies that aim to reduce the Build-Up of cholesterol and risk of CHD focus mainly on reducing the total and saturated fat intake. Dietary interventions that reduce saturated fat intake by simply three percent could even prevent about 100,000 new cases of coronary heart disease within the next 7 years. Once dietary saturated fats are decreased, they may be replaced with polyunsaturated fats, such as omega-3 fatty acids that lower both total cholesterol and LDL-cholesterol.
Although a person’s genetic inheritance has a lot to do with the likelihood of developing heart disease, it is becoming increasingly clear that modifying your lifestyle can improve the effects of your genes. Heart disease remains the leading cause of death in the U.S., but people can reduce their risk by adopting prevention habits. Some of the most crucial tactics are avoiding smoking, maintaining a desirable blood cholesterol level, keeping blood pressure in the normal range, and regularly engaging in aerobic exercise. Along with these lifestyle habits, alpha-linolenic acid can be taken as supplementation to improve the body’s ability to fight heart disease.
Alpha-linolenic acid has also been shown to lower the risk of stroke, which is the third leading cause of death in the U.S., after heart disease and cancer. Omega-3 fatty acids have also been shown to lower blood pressure by small but significant amounts and have also been able to lower levels of hypertension. Essential fatty acids also have the ability to reduce inflammation of the synovial fluid in the joints, which means that they can help in rheumatoid arthritis, a disease that affects at least forty million people in the United States.
Multiple sclerosis, a disease of the central nervous system that destroys myelin sheaths that cover the nerve and creates inflammation, has symptoms including blurred vision, dizziness, numbness, weakness, tremors, slurred speech, and staggering. Studies have shown that multiple sclerosis is at least partially caused by the deficiency of prostaglandins, which are produced from essential fatty acids.
Psoriasis, a skin disease that is characterized by patches of scaly skin on the knees, elbows, and scalp, but possibly anywhere, is considered essentially incurable by conventional methods, but dietary methods have offered some hope. Because of its rich essential fatty acid content, flaxseed oil is one of the natural therapeutic agents suggested for psoriasis. There is some evidence that suggests that a consistent supply of omega-3 oils may help to prevent fat-sensitive types of cancers, as well as inhibit breast, colon, prostate, and pancreatic cancers.
Do you experience muscle pain and inflammation?
April 25, 2007 03:30 PM
Everyone experiences muscle pain and inflammation due to overuse and exertion. We’ve all had those softball games, weekend camping trips or chore-intensive days when our body lets us know we’ve overdone it.
So, what can you do about it? Well, fortunately, there is a proprietary formula with clinically studied ingredients that provides a natural solution: FlexAgility MAX.
FlexAgility MAX is designed to reduce pain and inflammation due to overuse. Its clinically studied ingredients have been shown to help balance the body’s own inflammatory response. Let’s take a look at FlexAgility MAX and answer a few questions you may have about it.
Q. What is inflammation? Why does it happen?
A. Inflammation is actually an essential part of your body’s natural healing process. When some form of physical stress affects the body, the immune system responds by supplying defensive compounds to the stressed site. This is what causes the fluid Build-Up, pain and redness we typically associate with inflammation. And until the situation is resolved those symptoms will stick around. So, why is that good? Because without these signals – pain and inflammation – we’d probably do even more damage. In a sense, pain and inflammation are very effective stop signs.
The problem is, if our bodies are continuously bombarded by factors that trigger inflammation, these defenders (and their symptoms) are always around. This can mean unnecessary pain and inflammation following overuse and exertion.
Q. What does FlexAgility MAX have to do with inflammation?
A. FlexAgility MAX provides triple-action activity against occasional pain and inflammation, with powerful antioxidant free-radical scavengers, the enzyme bromelain, and a natural COX-2 inhibitor.
Q. So what is COX-2 and why should I inhibit it?
A. We’ve all been hearing a lot in the news about COX-2 inhibition and may have wondered about its connection to pain and inflammation. Let’s take a look:
Cyclooxygenase is an enzyme that comes in two main types, abbreviated for convenience: COX-1 and COX-2. The COX enzymes regulate compounds involved with inflammation, including prostaglandins. COX-1 is found throughout the body, and maintains the integrity of the stomach lining, circulation and kidneys.
COX-2 on the other hand, cruises along the central nervous system – it’s much more attuned to our brain’s sense of “what hurts.” Primarily activated by inflammatory stress, COX-2 generates prostaglandins – the hormone-like defensive compounds that cause the responses we associate with pain and inflammation due to overuse.
You can understand why so much research has focused on COX-2 inhibition. Decreasing its activity means short-circuiting the “inflammation cascade” that follows occasional overuse.
Because COX-1 is associated with a healthy stomach lining, it is not an enzyme you want to inhibit. Unfortunately, many products don’t know the difference between COX-1 and COX-2 – filing both with one blast.
Fortunately, there are ingredients in FlexAgility MAX that can tell them apart. One of them is IsoOxygene.
IsoOxygene is a patented hops extract shown in scientific studies to significantly inhibit COX-2, while leaving COX-1 alone. And, it is a 20 times more potent COX-2 inhibitor than other tested popular botanic products, including curcumin and grape seed.
Q. How do antioxidants support the body during times of inflammation due to overuse?
A. Overall, the body ahs a pretty darn good repair system. However, oxidative stress due to free radical damage can take its toll, especially during times of occasional physical stress. Free radicals and reactive oxygen species can damage cells, because they are hungry, unstable molecules in search of electrons. To find them, they attack other cells. These pillaged cells then become free radicals themselves, setting off a chain reaction of oxidative stress.
Free radicals are formed during the body’s normal functions, and can have benefits, such as neutralizing viruses and bacteria. However, in doing do, they erode the body’s own antioxidant defenses, too. And, free radicals typically become very active during times of inflammation due to overuse or other stressors.
The good news is that the herbal and antioxidant elements in FlexAgility MAX help support the body’s own natural anti-inflammatory defenses.
Take vitamin C, for instance. This extremely well-known antioxidant has been scientifically studied for its beneficial effects on muscle, collagen and connective tissue health. Collagen and connective tissue is what helps hold us together – literally.
And famous antioxidant, green tea, has been well-studied for the benefits of a polyphenol called epigallocatechin-3-gallate, or simply EGCG. In scientific and clinical studies, EGCG from green tea works as an overall antioxidant, scavenging free radicals, and supporting healthy collagen. In fact, one study showed that green tea polyphenols supported collagen health by 50% versus only 16% in controls.
The green tea extract in FlexAgility MAX is especially focused on these beneficial polyphenols. It’s standardized to contain 70% polyphenols – half from EGCG. The green tea acts in concert with elderberry and ginger in the formula to help prevent oxidative stress to the body due to occasional overuse.
Anthocyanins are natural antioxidants found in berries and vegetables. Black elderberry extract, one of the herbal ingredients in FlexAgility MAX, was shown in scientific studies to be more bioavailable – that is, more readily used by the body – than the natural bioflavonoids of other plants. Again, antioxidants help keep the body in optimum health- especially during times of physical stress.
Ginger, used for centuries in Ayurvedic medicine, provides strong, natural antioxidant activity. In fact, a recent scientific study found more than 50 separate antioxidants in ginger root.
Of course, there are many components of plants that show strong antioxidant properties. A scientific study comparing flavonoid antioxidant activity and inflammation have shown that rutin was the most effective in reducing the inflammation cascade.
Boswellia serrata is a tree found growing in the dry, hilly regions of
Another antioxidant ingredient in FlexAgility MAX, N-acetylcysteine (NAC), even helps the body produce more of its own antioxidants, cysteine and glutathione. In a double-blind, placebo-controlled clinical study, N-acetylcysteine inhibited occasional pain and inflammation due to overuse and attenuated fatigue by 26% compared to controls!
N-acetylcysteine has also been shown in scientific tests to act as an antioxidant, supporting healthy collagen and synovial fluid.
The last ingredient, bromelain, provides the enzymatic pathway used by FlexAgility MAX. Bromelain is a proteolytic enzyme derived from pineapple. Clinical and scientific studies showed benefits from bromelain in reducing pain and inflammation from occasional overuse.
So, there you have it- the triple action of FlexAgility MAX: COX-2 inhibition (and COX-1 sparing), antioxidant benefits, and enzyme support.
Q. Is there another product you’d recommend that I use with FlexAgility MAX?
A. One other product I recommend without hesitation is GS-500, a glucosamine sulfate supplement that has been shown to help build and support cartilage. The body’s connective tissue and cartilage include a natural compound called glucosamine. Supplemental glucosamine sulfate is up to 98% absorbable, so more glucosamine reaches the target structures. It has been clinically studied on its effect in building cartilage.
About Enzymatic Therapy:
Like Chris, Enzymatic Therapy is a trailblazer. Since our founding in 1981, we’ve been leading the industry with innovative natural products. After all, in 1993, Enzymatic Therapy introduced glucosamine sulfate, shown to help build and support cartilage, to the
In the intervening years, Enzymatic Therapy has been at the frontline of innovation and invention. Many revolutionary precuts, including Saventaro, Cell Forte, Heartburn Free, Petadolex Patented Brain Support, Whole Body Cleanse, Earth’s Promise, Hot Plants for Him and Hot Plants for Her have been introduced by Enzymatic Therapy.
One of the newest products, (and the reason you’re reading this) is FlexAgility MAX. FlexAgility MAX works with the body’s own natural anti-inflammatory pathways to relieve pain and reduce inflammation due to occasional overuse. Our proprietary FlexBend of ingredients, combined with antioxidants and the proteolytic enzyme, bromelain, is unique among natural products.
What will Sytrinol do for me?
February 27, 2007 09:21 AM
Clinical results have demonstrated that Sytrinol can improve total cholesterol levels up to 30%, LDL cholesterol levels up to 27%, and triglyceride levels up to 34% within four to twelve weeks. Additionally, clinicals have demonstrated Sytrinol can have a positive impact on apoprotein B and apoprotein AI levels as well as playing a significant role as an anti-inflammatory. Sytrinol can do all this without the negative side effects associated with pharmaceutical drugs. The tocotrienols in Sytrinol have been shown to reduce arterial plaque Build-Up.
Mega-Folinic - Bio-Active Form of Folic Acid
January 31, 2007 03:59 PM
The Refreshing Feeling of All Things New
December 05, 2005 07:07 PM
The Refreshing Feeling of All Things New.
Springtime! We realize it's time to open the windows and let the fresh air in once again after a season of having everything shut up tight. More time spent indoors through the winter can mean months of recireculated air, less time spent outside, and overindulgence in holiday food. That's a recipe for toxic Build-Up. As you start to think about spring cleaning you will do inside your house, don't forget about the cleansing that is good for the mind and body. Decker Weiss, NMD To cleanse and detoxify the whole body, rely on Enzymatic Therapy's Whole Body Cleanse†. The National Cancer Institute recommends eating 20 to 35 grams of fiber a day, yet most Americans get only 15 grams. It's clear the right amount and the right type of fiber can make a real difference in cleansing our system and maintaining regularity day by day.† Taking Whole Body Cleanse for thorough periodic detoxification and Fiber Fusion to tone and renew your system on a daily basis is a great way to greet Spring.†
A Time for Rejuvenation.
Every day we are exposed to toxins in our food, water, and the air we breathe. The natural variation in volume and variety of today's environmental contaminants is a challenge for your body's built-in detoxification systems. Toxins Come from Many Sources: Foods that may have been exposed to pesticides, herbicides and fertilizers.
Hormones used in raising livestock.
The burning of fossil fuels in automobiles and utility power plants which can affect air quality.
Treated wastewater that flows into rivers, lakes and streams which can contain unwanted pollutants.
Whole Body Cleanse† and Simple Cleanse † from Enzymatic Therapy handle the environmental toxins you take in from the environment (like pollutants) as well as toxins that you make yourself (like free radicals), without depleting your body's store of beneficial nutrients.† Which on is right for me?
ALPHA GPC - Improves Mental Performance
June 28, 2005 06:21 PM
The quality of our life experience—and our ability to live life to the fullest—is a direct result of optimal brain function. Only a few years ago, nothing could be done to stem the tide of poor circulation, forgetfulness and “mental fog.” But neurological science exploration has identified a fundamental brain compound critical to attention, learning, memory, and even the higher cognitive functions of reasoning and intuition. Research confirms that L-alpha-glycerylphosphorylcholine (called Alpha-GPC for convenience) is crucial to neuronal function and structure. Derived from purified soy lecithin, Source Naturals ALPHA-GPC readily converts to acetylcholine in the brain, helping to maintain neuronal structure integrity. Source Naturals provides an easy and convenient means to profoundly impact the very nexus of our body and mind.
GPC Is Unique
No other nutritional compound comes close to GPC in its ability to boost critically important acetylcholine levels. Found in both the brain and the peripheral nervous system (including the nerve-muscle junctions), acetylcholine is a key nerve messenger molecule, or neurotransmitter. Aging brains are characterized by functional deficiencies in both acetylcholine and its cholinergic receptors. GPC is a highly bioavailable supplement that boosts acetylcholine levels to improve cognitive function. It is also a major choline reservoir, helping to protect the brain against damage from poor circulation and potentially toxic metabolites.
Deficiencies in acetylcholine can cause the body to break down phosphatidylcholine for its choline content, leading to the death of brain cells. Yet in controlled clinical trials of middle-aged subjects taking GPC, reaction time was enhanced and there was improved energy generation and electrical coordination in the brain. For older subjects, double-blind trials demonstrated that GPC had superior benefits over certain other brain nutrients for mental focus, recall, verbal fluency—a unique, marked overall enhancement of mental performance. GPC is an example of what the great Linus Pauling referred to as “orthomolecules,” that is, molecules that are “orthodox” or “correct” for the body. GPC excels as a protective nutraceutical for memory loss and mood enhancement. It protects cells of the brain (and other organs) from damage, shielding a range of important biomolecules against toxin Build-Up.
Extensive Clinical Testing
In clinical trials that involved more than 5,000 patients, GPC showed marked improvement in overall brain performance. Depending on the particular trial, 50-70 percent of the patients who received GPC had their mental functions improved to a degree “meaningful to life quality.” GPC has shown revitalizing effects on the declining brain, and preliminary evidence suggests GPC may act on the pituitary gland to partially restore its capacity to make vital for cell maintenance and longevity. Other unique brain features of GPC are its benefits for attention and recall in young healthy adults, and its superior bioavailability. GPC readily crosses the bloodbrain barrier to raise brain choline levels within a few hours following oral intake. GPC helps with body-mind integration by being a ready reservoir for acetylcholine. This neurotransmitter is ubiquitous in brain circuit maturation, expansion, renewal and repair, as well as in the “agility” or adjustments of the circuitry that occur during adult life. In addition, an animal study has shown that GPC increases the release of GABA (gamma-aminobutyric acid), the most important and abundant inhibitory neurotransmitter in the brain. It acts as a “balancer” for the brain and helps induce relaxation and sleep. Without sufficient GABA, neurons fire at random, unable to make sense of incoming signals. GABA helps minimize “neural noise,” making it easier to focus and concentrate.
Why you should take GPC:
All Calories Are Not Created Equal
June 25, 2005 07:49 PM
All Calories Are Not Created Equal
When we eat more than our daily energy requirements (and most of us do), the extra energy is stored as fat. The human body is designed to stockpile fat very easily. This tendency is related to innate mechanisms intended to protect us against starvation or the threat of a diminished food supply. Fat cells provide extra fuel which can be utilized if necessary to sustain life. Those survival fat pounds settle on the hips, waist, thighs, upper arms and back, not to mention around organs, like the heart and kidney. Some ethnic groups, whose ancestors repeatedly suffered from famines, are especially efficient in energy storage. These include the Pima tribe48 in the United States, the Aborigines of Australia,49 and many of those of African descent.41
Fats are very readily converted to pounds. Carbohydrates and proteins require more complicated digestive processes to convert and store their energy than fat does. Calories from carbohydrates and proteins are usually burned and thrown off as heat (thermogenesis). Naturally, overeating proteins and carbohydrates can result in weight gain, however the body has to work harder to convert these nutrients to fat stores. It takes 20 to 25 percent of the energy in carbohydrate and protein to convert them into body fat. It only takes about 5 percent of the energy content of dietary fat to store it as body fat. Fat is also twice as energy dense (9 calories per gram) as carbohydrates or proteins (4 calories per gram) making fat at least twice as dangerous from a weight gain standpoint.50 Blood taken from an individual soon after they have eaten a double cheeseburger, french fries and a thick milk shake will often be a milky pink color due to the infusion of fat from the digestive system. This fat circulates throughout the system until it is either burned or stored.
A Winning Combination
Most people would agree that exercise combined with a low-fat, high-fiber diet would be a winning combination for maintaining and improving health. Exercise is important in any health maintenance program. It is especially important in weight control since the amount of energy we expend in the resting state, our Resting Metabolic Rate (RMR), is a function of our muscle mass and tone.51,52 There is a tendency for us to lose muscle mass and gain fat pounds as we age. In part, this is due to life style changes. Instead of flying kites we fly desks! Nevertheless, our capacity to increase our muscle mass is undiminished with age.53 The lack of exercise rather than the abundance of candy is thought to be the primary cause of childhood obesity.54
Eating a low-fat, high-fiber diet will produce some weight loss even in nor-mal weight subjects.55 The reason for this may well be the balance between fullness and satiety.56 It is a proven fact that we can easily eat an excess of fat before we feel full or satisfied. This is because fats are twice as energy dense (9 calories/ gram) as carbohydrates or proteins (4 calories/gram). By the time we are full, we have over eaten. Increasing our fiber intake helps us feel full. (Of course expensive gastric bypass surgery is another alternative.57) Eating a highfiber diet helps us to feel more than just full. Low-fat, high-fiber diets are found to lead to a general lowering of cancer rates.58 Though the above combination of exercise, low-fat, and high-fiber may work in theory; making the theory work in practice is quite another story.
Technology works against us in some ways as evidenced by this comment a woman made about her husband’s physique: “He has added 20 pounds of lap since he got his lap-top [computer].” And just try to get a low calorie meal over your lunch hour. In Feburary 1996 McDonald’s, an international fast food franchise, announced that it would be dropping its five-year experiment with the low-fat McLean burger (12 grams of fat). Also gone from the menu will be the Chef’s salad and the side salad. The taste of the Big Mac (35 grams of fat) has apparently won out over its McLean competition. The salads seem to be a casualty of convenience. Eating a salad in the car after a quick pickup at the drivethrough can be a bit challenging.
Fortunately, state-of-the-art research in the area of weight loss has discovered that through the addition of certain supplements and nutrients, the process of decreasing the amount of fat we process in the stomach and boosting the amount of fat we burn can be expedited. For those of us who suffer from a “fat imbalance” or a condition where we store more fat than we burn, it is often a matter of life or death to lose fat in order to protect our arteries and heart.
The Secret t o Weight Loss . . . An Ounce of Prevent ion Most weight-reducing strategies have to confront the “after the fact” problem of burning already stored fat. Like most of our medical practices, we routinely become sick or fat and then go about the business of trying to remedy our ills. Despite Poor Richard’s advice that “an ounce of prevention is worth a pound of cure,” we continually eat high-fat diets, and wait until we have to pay the piper before most of us take serious action. It’s much easier to prevent a fat Build-Up than to reverse the damage that carrying extra fat stores can cause. Going on a diet is nothing less than torture and usually means giving up all the foods we like to eat. Yet dieting seldom gets to the root cause of our excess weight which most often is that we eat too much fat, when not dieting. The body begins to digest lipids in the stomach and intestines.
The diagram in Figure 1 illustrates the steps involved in getting fat into our bloodstream.59 There are four steps in fat digestion: 1) acidolytic breakdown of food in the stomach; 2) enzymatic breakdown (lipolysis) of the fats (triglycerides, TGs) into fatty acids (FAs) and beta-monoglycerides (b-MGs); 3) formation of soluble mixed micelles with bile acids; and 4) absorption through the intestines. If we could tie up excess fat before it was absorbed, we could spare our physiological systems the stress of having to deal with that fat. Ideally then, what we need is a substance that prevents fat absorption.
Physical and Mental Stamina
June 25, 2005 01:03 PM
Many studies have been done to determine the effectiveness of ginseng in a variety of countries. Incomplete results have occurred in some instances. Long-term studies are most often recommended because ginsengs properties may not be seen in immediate experiments but are more effective when taken in small doses over a period of time. There have been enough credible studies done to now determine that high quality ginseng plants do contain active constituents known to be beneficial. Research has shown that the roots are effective against bronchitis and heart disease.16 Ginseng has been found to reduce blood cholesterol, build the immune system, improve brain function and memory, increase physical stamina, stimulate the function of the endocrine glands and strengthen disorders of the central nervous system.
Physical and Mental Stamina
A study down in the late 1950s and early 1960s by Brekhman and Dardymov in Russia involved an experiment with Soviet soldiers. They were studying the pharmacology and reactions of different varieties of East Asian ginseng. Some were given an extract of Asian ginseng and others a placebo before running a 3-kilometer race. Those given the ginseng ran faster with less fatigue than those given the placebo.17 Other tests performed by Brekhman involved gauging reading capacity after taking ginseng. It was noted that not only was the work and reading ability improved, but the effects continued for up to six weeks after the treatment.18
Another study giving radio operators either an Asian ginseng extract or placebo. The group given the ginseng performed better with fewer mistakes. The ginseng helped to increase stamina and mental function.19 A study involving rats followed the results when they were put in extremely cold water and forced to swim for a long period of time. The rats given the Asian ginseng were able to swim longer than the control group which indicated anti-fatigue activity. It is also important to note that ginseng increased the recovery rate of the exposed rats. The process was initiated in order to see if the point of exhaustion could be increased with the addition of ginseng. The results were favorable.20
Ginseng seems to be able to help slow glycogen utilization in the muscles when exercising. Fatigue accom-panying prolonged exercise is due in part to the depletion of glycogen and lactic acid Build-Up. Fatty acids are used as the energy source when there is enough oxygen available to reach the muscles reserving the glycogen stores to increase the body’s performance and reduce fatigue.21 Athletes may benefit from using ginseng to help improve and prolong their performance and abilities under stress during training and competition.
Serious athletes throughout the world use ginseng regularly. Some Olympic athletes take ginseng daily to increase and enhance their physical performance. Siberian ginseng has been found to help improve mental abilities in geriatric patients.22 This may be of benefit to all individuals as they age especially those prone to senility and Alzheimer’s patients. It is also thought to help an aging heart and brain tissue under stress and sustained work.23
Siberian ginseng has also been found to help increase energy and performance. Japanese medical researchers studied the extract of Eleuthero ginseng to determine anti-fatigue activity. The results showed increased physical performance and ability after taking the ginseng.24
The Cardiovascular System and Free Radicals
June 25, 2005 11:49 AM
The Cardiovascular System and Free Radicals
It is the bioflavonoid content of ginkgo which enables the compound to scavenge free radicals so effectively. The flavonoids in ginkgo help protect cells against free radical contact. These flavonoids have an enzyme-regulating effect also found in citru-derived bioflavonoids with one important difference: the efficacy doses reported for ginkgo are much lower. In addition, these bioflavonoids provide protection to blood vessels against the damaging effect of plaque Build-Up. Scientists have discovered that is the antioxidant action of ginkgo which helps pre vent damage to heart muscle. Ginkgo reduces the formation of free radicals. Ginkgo may provide some protection from exposure to damaging ultraviolet light.
The Brain’s Vulnerability to Oxidants
The antioxidant action of ginkgo helps to keep ample supplies of oxygen to brain neurons which are involved in memory retrieval. The flavonoids in ginkgo help to decrease the metabolism of oxidants in brain cells which can help prevent reduced blood flow to brain tissue. The antioxidant properties of ginkgo are most evident in brain tissue, which is made up of nerve cells. Brain cell membranes are compressed of a high percentage of unsaturated fatty acids which make them p a rticularly vulnerable to free radical damage and hypoxia (lack of oxygen).
The brain has little in the way of energy reserves and requires a continual supply of glucose and oxygen. When circulation is compromised, both of these components are reduced. If blood flow is diminished enough, brain cells will die. Ginkgo helps these cells to utilize glucose and boosts oxygen supply. As a result, energy production in brain tissue is enhanced.
June 25, 2005 10:59 AM
Ginkgo may be considered a wonder herb in that it has numerous medicinal applications. Its ability to increase oxygen to living tissue by boosting blood flow makes it invaluable for a number of disorders including heart problems, strokes, and geriatric senility.
Traditionally, the Chinese have used ginkgo to treat bronchial, asthmatic and pulmonary conditions. Recently, research has indicated that certain compounds contained in ginkgo have been shown to effectively dilate arteries, veins and capillaries, which results in increased peripheral blood flow. It is this enhanced circulation of blood which seems to benefit the brain in particular.
Because it effectively boosts brain blood flow, ginkgo may have important potential for treating senility, short-term memory loss, tinnitus (ringing in the ears) and other types of vascular diseases.
Ginkgo has been used for Raynaud’s disease, intermit tent claudication, numbness, ve rtigo and impotence. It is common practice in Europe and Asia to regularly prescribe ginkgo to improve mental function.
Not commonly known is ginkgo’s ability to treat respiratory disorders and stress. It can also function as an excellent antioxidant, due to its bioflavonoid content. Ginkgo also participates in enzyme regulation and protects the blood vessels against plaque Build-Up and the liver against toxic damage.
CLA and Ather osclerosis
June 22, 2005 09:47 PM
CLA and Ather osclerosis
CLA may well have benefits in the battle against heart disease as well. The leading cause of death in the United States is heart disease or related diseases of the circulatory system. Indeed, U.S. statistics show that about half the people in the United States die that way.
In 1989, for example, some 2 million Americans died, and about 950,000 of those died as a direct or indirect result of heart disease. T h a t’s far more than the total number of deaths fro m AIDS, shootings, bombings and accidents combined.3 4 For pers p e c t i ve, let’s discuss what happens when a new s w o rthy accident o c c u r s — l e t’s say an airline crash that kills 200 people.
Statistically speaking, five times that many people will die the same day of heart disease, as many as two each minute. Thankfully, doctors have made great progress in battling these conditions, and researchers have discovered that a healthy lifestyle can help the heart. Indeed, as almost everyone knows, balanced nutrition, lower stress and plenty of exercise can lead a person to be more healthy and to run a lower risk of heart attack and other heart conditions. Evidently, at least in animals, CLA seems to possess the ability to cut risks as well. Dr. Pariza and two colleagues, Kisun Lee and David Kritchevsky, studied a group of 12 rabbits that were fed a diet high in fat and cholesterol. They gave six of them CLA. In the academic journal Atherosclerosis, they reported that two dangerous compounds, LDL cholesterol and triglycerides, were “markedly lower” in the six that had diets supplemented with CLA.
When the scientists looked at the aortas—the largest artery leading from the heart—of these animals, they also found a lot less blockage than in those that didn’t have CLA. This is how they summarized their results: “CLA appears to be hypocholesterolemic and anti-atherogenic.”35 This is pretty bold stuff for cautious scientists. Though the words are complex, the statement is clear: CLA seems to cut cholesterol and makes it so veins won’t clog as easily. This finding was surprising to Dr. Pariza. Science shows that straightened fatty acids (trans-fatty acids) of which CLA is one, usually tend to increase the risk of heart disease. Pariza said it only made sense to test CLA with this kind of science. Indeed, the best he would hope for would be no effect.36 In 1996, another group studied atherosclerosis and hamsters supplementing diets with CLA. CLA didn’t cut the amount of cholesterol in the blood within three months, but it did cut the amount of fatty Build-Up in the aorta of the hamsters.37 The bottom line on heart disease and CLA? Because two different types of animals show less clogging of the arteries, it seems clear that a good chance exists for the same thing to happen in humans. Of course, as with the cancer research, solid studies in humans need to be conducted for researchers to say definitely that this can cut your risk of heart disease. But until that day, the news is good: A nutritional regimen that includes solid antioxidants like vitamin C and vitamin A, that includes magnesium,38 coenzyme Q10,39 and that includes other important circulatory system-fortifiers would likely benefit from CLA. Couple that nutrition with a healthful lifestyle, and your chances of living longer and living better will likely increase.
Mane Attraction - lustrous Hair...
June 14, 2005 08:19 AM
Mane Attraction by Chrystle Fiedler Energy Times, February 12, 2004
Everyone wants thick, lustrous hair. Think of the allure attached to the locks of Samson and Lady Godiva and-fast-forward to the present-the full heads of Antonio Banderas and Julia Roberts.
" We're naturally attracted to hair as humans; it catches the light, it frames the face, we like the feel of it," says Catherine Jones, ND, LAc, a resident naturopathic physician at Bastyr Center for Natural Health in Seattle, Washington. "Fair or not, historically in many cultures, rich, thick hair has been a sign of fertility and strength."
Along with that allure, latching onto natural ways to have great-looking hair gives you the benefits of looks and health. Every hair starts with a shaft that grows from a root. "The root is contained deep within the hair follicle," says Dr. Jones. "Each one has a sebaceous or oil gland, which supplies the hair with necessary lubrication as it approaches the surface of the scalp." Each hair follicle has its own growth cycle, including a resting period, the telogen phase, when hair falls out. Because of these constant hair phases, each of us loses, on average, about 100 hairs a day.
" The number of hairs the average person loses in a day tends to increase in the fall as the leaves fall from the tree and tends to decrease in the spring as the bulbs emerge from the soil," Dr. Jones says. "We really are connected to nature." Stress-due to rapid weight loss, infection, anemia, prolonged illness, hormonal changes, hypoactive thyroid disease, autoimmune conditions, eczema or psoriasis-can influence hair growth and loss.
Hair consists of proteins, lipids (fats), carbohydrates and pigment (gray hair has reduced pigment; white, none at all). Each shaft's structure is divided into a medulla, a cortex and an outer cuticle. " The cuticle is coated with an outside lipid-like layer, which protects the hair," says Dr. Jones. "As the hair grows out of the follicle, the cortex and cuticle become keratinized and harden." Dry or damaged hair is more susceptible to breakage. "The condition of the cuticle affects how the light reflects off the hair, giving it highlights and luster," Dr. Jones says. "Luster is affected both by what occurs inside the body as the hair is developing and what happens to the hair after it has grown from the shaft."
Sun, heat, moisture, pollution and hair products, dyes and bleaches can all dull the hair. "Applying chemical solutions to the hair, color, permanent waves or curl relaxers, damage the protein molecules that wrap around the shaft, leaving hair brittle and dull," says Christina Pirello, author of Glow: A Prescription for Radiant Health and Beauty (HP Books).
Conditioners and oils can leave a residue or weigh hair down. Hair sprays and products that contain alcohol can dry and damage the hair, as can using blow dryers and curling irons.
To combat hair-raising havoc, feed your hair natural nutrients for health. Silica and plants that contain silica/silicon both strengthen hair and promote growth. "Silica is a good mineral for hair health," says Walter Siegordner, founder of The Aurora Group, a personal care company. "It helps in the keratinization process of the cells that produce hair."
" Silica is a mineral that is involved in the synthesis of bone and connective tissue," adds Dr. Jones. "The hair follicle contains connective tissue so silica may promote the health and function of the follicle itself." Silica-containing herbs include nettles (Urtica dioica), horsetail (Equisetum arvense), oatstraw (Avena sativa) and alfalfa (Medicago sativa).
Sea plants like seaweed and kelp also provide vital nutrients. "Sea plants are essential ingredients in many natural shampoos and can be used to fortify damaged hair," says Pirello. "They're rich in vitamin A that prevents the Build-Up of dead skin cells, which can clog the hair follicles, inhibiting the growth and health of the hair, and also contain vitamin B, linked to the prevention of oily hair, baldness and dandruff. Calcium found in sea plants is essential to the structure of the hair shaft."
Eaten on s daily basis, sea plants are rich in nutrients that help maintain healthy, shiny hair, free of split ends, Pirello says. Try wakame in soups and salads, kombu or kelp in bean and vegetable dishes, nori in sushi, and hiziki and arame as side dishes. Since hair health is affected by digestive health, the fiber found in whole grains also helps. "Fiber prevents accumulation in the intestines that can result in the formation of toxins," says Pirello.
Miso, she adds, is especially good hair food. It "is rich in living enzymes that ease digestion, fortify the quality of the blood nourishing the body and hair, and provide us with essential oils, vitamins and minerals."
Key nutritional support includes adequate protein and amino acids, essential fatty acids such as cold-pressed flax seed oil and fish oil, copper, vitamin A, vitamin E, vitamin D, biotin, iron and vitamin B5 (pantothenic acid). Zinc and selenium can help combat the effects of hyperthyroidism, which can result in thinning, lackluster hair.
Vitamin C can boost adrenal health. "When the adrenals are overtaxed and become fatigued, hair follicles will go into a resting phase," says Dr. Jones. (If you have a medical condition, she adds, check with your health care practitioner first before taking supplements.)
In Traditional Chinese Medicine, hair is associated with the kidneys' qi, energy that originates in these organs, and with blood quality. " From the traditional Chinese perspective, excess amounts of fat, protein, dairy, sugar, alcohol and salt in the diet acidify the body, damage the Kidney qi and are not good for the hair," says Dr. Jones. A diet rich in vegetables and grains is a great way to support healthy hair. "Iron and mineral-rich foods are considered blood builders and hair tonics. Foods such as blackstrap molasses, seaweed, nettles, and the herb polygonum multiflorum (also known as He Shou Wu and Fo-Ti) have been used throughout the years. Fo-Ti has also been used to prevent graying of the hair and support the immune system."
" Hair is extremely strong but at the same time it's extremely delicate," says Barsoum Bouchar, a cosmetologist and owner of the Virtuoso Salon in Birmingham, Michigan. "Many products work against the hair texture, so the cuticle is always raised. This causes tangles and split ends. With blow dryers, chemicals, colors and styling elements, the hair is tremendously abused." If you don't have to chemically treat the hair, he says, don't.
When replenishing the hair it's important to remember that it's composed of 97% protein and 3% moisture, says Bouchar. Shampoo cleanses the hair and removes buildup. "A moisturizer brings moisture back into the hair and smoothes the cuticle down, which is what makes hair shiny and gives it bounce. The one key ingredient in both shampoo and moisturizers is aloe vera. It heals the hair." " Avoid products with harsh surfactants like sodium laurel sulfate and propylene glycol," warns Siegordner. "These decrease the circulation in the scalp, reducing the pathway for nutrition to the hair bulb." Conditioners that aren't natural can also cause Build-Up. "When you apply heat to the hair through blow drying or styling, you end up 'burning' the hair," says Bouchar.
To stimulate hair growth, add a few drops of essential oils of rosemary, lavender and thyme to jojoba and almond oils, and rub into the scalp. Leave it overnight and then rinse it off. " Essential oils have antimicrobial and antifungal properties, stimulate the circulation to the hair follicles and combat dryness. They also smell good," says Dr. Jones.
For hair that's not chemically treated, "a vinegar rinse cleanses the hair, removes Build-Up and boosts shine," says Bouchar. Use one part vinegar to ten parts water, apply after a shampoo, comb though and rinse it off. To naturally lighten the hair, use the same ratio in a lemon rinse for five minutes for, say, four days in a row, and then stop.
If you want to color your hair, choose natural elements, too. "The best natural dye is henna," says Bouchar. "It's organic, just like hair is." Blonde hair becomes warmer with a coppery tone, brunette hair takes on a mahogany hue, gray hair looks like highlights.
To find a good natural hair stylist, Bouchar suggests asking which products they use and why. If your hair is chemically treated, it's especially important to work with a stylist you trust for the best care.
Keep your eye on the big picture when it comes to hair health. "Be proactive and treat the body holistically," urges Dr. Jones. "Nourish the glands, the organs and the vessels that are responsible for getting the necessary nutrients to the hair follicle. Pay attention to the physical, emotional and mental aspects of health. Once hair is lost it may come back but it will likely be thinner than it was before. It's important to take care of what you have."
Magnesium Malate - Fight Aluminum Build-Up ...
June 03, 2005 11:44 AM
ALUMINUM has been the focus of much negative attention lately– numerous studies have indicated that aluminum accumulates in the body, especially in nerve tissues, potentially causing harm. Recently, scientific researchers have discovered that one compound may have the powerful effect of diminishing this unwanted aluminum accumulation. On the cutting edge of nutrition science, Source Naturals is one of the first companies to introduce this powerfully protective compound: MAGNESIUM MALATE.
THE DANGERS OF ALUMINUM
Aluminum is a naturally occurring metal. It has been the subject of recent studies on aging, and some scientists consider it to be harmful. It may come as a surprise that aluminum can be found in a wide variety of foods and manufactured products, such as baking powder, non-dairy creamers, antacids, deodorants, cookware, and food containers. Even tap water contains aluminum. With so many possible avenues for ingesting aluminum, we may be consuming more than nature originally intended. Mounting evidence that aluminum tends to accumulate in the body is even more cause for alarm. Unfortunately, there are no overt warning signs of excess aluminum accumulation, until levels become high enough to have adverse effects on health.
THE ALUMINUM-MAGNESIUM LINK
Researchers have suggested that aluminum may be more likely to accumulate in the brains of persons whose diets are Magnesium-deficient — which, unfortunately, includes 90% of Americans! Several studies have shown that animals fed diets low in Magnesium accumulate high concentrations of aluminum in the Central Nervous System. One of Magnesium’s many functions is to activate the enzyme tubulin involved in the maintenance of nerve tissue cells. It has been suggested that when there is not enough Magnesium in the body to plug into the appropriate receptor site on the tubulin enzyme, aluminum takes its place instead. This leads to the inactivation of tubulin and, consequently, inadequate nerve function. Because a Magnesium-deficient diet may increase the amount of aluminum taken up and stored by the body, it is vitally important that we take in sufficient amounts.
MAGNESIUM MALATE — A ONE-TWO PUNCH
MAGNESIUM MALATE supplies a one-two punch in combating excess aluminum accumulation. In addition to providing 45% of the U.S. R.D.A. for Magnesium, MAGNESIUM MALATE also supplies Malic Acid. Found abundantly in fruits such as apples, Malic Acid is also produced in the human body. It is a metabolite of the Krebs cycle, the set of biochemical reactions used to produce 90% of all energy in the cells of the body. Malic Acid readily crosses the Blood-Brain-Barrier and has been shown to bind to aluminum. It functions in the body by drawing aluminum away from the tubulin enzyme, so that Magnesium can plug into the receptor sites instead. Malic Acid’s unique ability to bind with aluminum means it can be flushed out of the body, preventing unwanted Build-Up.
THE PRO-ACTIVE APPROACH
With all of the negative evidence mounting against aluminum, educated consumers will want to take precautions in order to maintain their health and well being. Of course, the best way to avoid excess aluminum is to cut back on aluminum intake from known sources. Use only stainless steel or cast iron cookware, and look for aluminum- free deodorants and antacids. Always use filtered or spring water for drinking and cooking. And for those who want to take a pro-active approach, adding MAGNESIUM MALATE to your supplement regimen may be your best bet in depleting unwanted aluminum Build-Up in the body.
Heart Science - A Five-Tiered Approach to Heart Health ...
June 02, 2005 12:07 PM
Your heart is crucial to every function of your body. It is the sole organ which pumps oxygen-rich blood through the entire circulatory system, feeding your cells and making life possible. Only recently are Americans realizing the importance of a proper low-fat diet, regular exercise, giving up cigarette smoking, and cutting down alcohol consumption to maintaining a healthy heart. Unfortunately, there has been a huge gap in the number of nutritional supplements which provide nutrients and herbs to support normal heart function. That’s where Source Naturals HEART SCIENCE comes in. Two years in the making, and backed by numerous scientific studies, the nutrients in HEART SCIENCE are some of the most soundly researched of all. Combining high potencies of these super-nutrients, HEART SCIENCE is the most comprehensive, cutting edge nutritional approach to proper heart care available.
Source Naturals HEART SCIENCE— The Five Tiered Approach to Heart Health
Your heart never rests. Even while you sleep, your heart must keep working, relying on the constant generation of energy by the body for its very survival. If this vital organ stops beating for even a short amount of time, all bodily functions cease and life ends. Source Naturals HEART SCIENCE helps support heart function on the chemical, cellular, structural, and energetic levels. This broad spectrum formula includes ingredients specifically geared for
Energy Generators for An Energetic Organ
Every day, the human heart beats about 104,000 times, pumping over 8,000 liters of blood through the body! Because it requires so much energy to perform efficiently, the experts at Source Naturals included specialty nutrients in HEART SCIENCE such as Coenzyme Q10 and L-Carnitine — integral factors in the body’s energy production cycles — to enhance the body’s energy supply.
There are three main interconnected energy generating cycles in our cells — the Glycolytic (sugar-burning) cycle, the Krebs’ (citric acid) cycle, and the Electron Transport Chain. Together they supply about 90 to 95% of our body’s entire energy supply, using fats, sugars, and amino acids as fuel. Coenzyme Q10 is one of the non-vitamin nutrients needed to maximally convert food into ATP (the energy producing molecule). It is the vital connecting link for three of the four main enzyme complexes in the Electron Transport Chain, the next step in energy generation after the Krebs’ cycle. Using the raw materials generated by the Krebs’ cycle, the Electron Transport Chain produces most of the body’s total energy! The heart is one of the bodily organs which contains the highest levels of CoQ10, precisely because it needs so much energy to function efficiently.
CoQ10 is one of the most promising nutrients for the heart under investigation today. It has been postulated that as a result of its participation in energy production, CoQ10 improves heart muscle metabolism and the electrical functioning of the heart by enhancing its pumping capacity.8 Many factors such as a high fat diet, lack of exercise, and cigarette smoking can lead to suboptimal functioning of the heart, and therefore failure of the heart to maintain adequate circulation of blood. Interestingly, people whose lifestyles reflect the above factors also tend to have depleted levels of CoQ10 in the heart muscle.10
Researchers suggest taking between 10-100 mg per day of CoQ10;18,29 HEART SCIENCE provides an impressive 60 mg of CoQ10 per 6 tablets. Similar to CoQ10, L-Carnitine is important for energy production in heart cells. It is a natural amino acid-like substance which plays a key role in transporting fatty acids, the heart’s main source of energy, to the mitochondria, the “power plants” of each cell, where they are utilized for the production of ATP. Heart and skeletal muscles are particularly vulnerable to L-Carnitine deficiency. Studies have shown that supplementation with LCarnitine improves exercise tolerance in individuals with suboptimal heart and circulatory function, and seems to lower blood lipid status and increase HDL (good) cholesterol.16, 22 Each daily dose of HEART SCIENCE contains 500 mg of this extremely important compound.
Like CoQ10 and L-Carnitine, B Vitamins help improve the ability of the heart muscle to function optimally. Each B Vitamin, after being converted to its active coenzyme form, acts as a catalytic “spark plug” for the body’s production of energy. Vitamin B-1, for example, is converted to Cocarboxylase, which serves as a critical link between the Glycolytic and Krebs’ Cycles, and also participates in the conversion of amino acids into energy. A deficiency of B coenzymes within contracting muscle cells can lead to a weakened pumping of the heart.21
HEART SCIENCE is formulated with high quantities of the most absorbable forms of B Vitamins providing maximum nutrition for the high energy demands of heart cells.
B Vitamins also play a crucial role in the conversion of homocysteine, a group of potentially harmful amino acids produced by the body, to methionine, another more beneficial amino acid. While it is normal for the body to produce some homocysteine, even a small elevation in homocysteine levels can have negative implications. It is well documented that individuals who are genetically predisposed to having elevated homocysteine levels (homocysteinemics) tend to have excessive plaque accumulation in the arteries and premature damage to endothelial cells (cells lining the blood vessels and heart).26 Researchers have found that even those without this genetic abnormality, whose homocysteine levels are much lower than those of homocysteinemics, still have an increased risk for premature endothelial damage and the development of plaque in the arteries.24, 26 One study conducted among normal men and women found that those with the highest levels of homocysteine were twice as likely to have clogged arteries as were those with the lowest levels.24 Furthermore, it was found that the lower the research subjects’ blood levels of folate and B-6, the higher their homocysteine levels.24 Another study found that Folic Acid administered to normal men and women who were not even deficient in folate caused a significant reduction in plasma concentrations of homocysteine!3 In order to regulate homocysteine levels, it is critical to provide the body with sufficient amounts of B-6, B-12, and Folate, whether through the diet or through supplementation. HEART SCIENCE includes high levels of these three nutrients, providing B-6 in the regular and coenzyme form for maximum utilization.
The Dangers of Oxidized LDL Cholesterol
While many people have heard that high cholesterol levels may negatively affect normal heart function, few people understand exactly what cholesterol is, or how it can become harmful. Cholesterol is a white, waxy substance produced in the liver by all animals, and used for a variety of necessary activities in the body. Your liver also manufactures two main kinds of carrier molecules which transport cholesterol throughout the system: Low Density Lipoprotein (LDL) and High Density Lipoprotein (HDL). Cholesterol is either carried out by LDL from the liver to all tissues in the body where it is deposited, or carried back by HDLs which remove cholesterol deposits from the arteries and carry them to the liver for disposal. Because of this, LDL cholesterol is considered damaging, while HDL is considered protective. Problems occur when there is too much LDL cholesterol in the body and not enough HDL.
When the body becomes overloaded with fat, an over-abundance of LDL particles are manufactured to process it, and they in turn become elevated in the body to a degree that the liver cannot handle. Rich in fatty acids and cholesterol, these particles are highly susceptible to free radical attack (oxidation). Once oxidized, LDL particles are no longer recognized by the body, which attacks them with immune cells. Immune cells which are bloated by oxidized lipids (called foam cells) are a key factor in the development of “fatty streaks” — the first sign of excess arterial fat accumulation. The bloated immune cells accumulate in artery lesions and create plaque in blood vessels, leading to obstruction and constriction of the vessels. Plus, these lodged foam cells continue to secrete free radicals into the bloodstream, making the problem worse.
The development of lesions in the arteries is not an uncommon problem. Arterial (and all blood vessel) walls are composed of a chemical matrix which holds the endothelial cells in place. That endothelial layer is the first and most important line of defense in preventing large molecules, such as cholesterol and fat, from entering the vessel wall. This matrix is composed of proteins, collagen, elastin, and glycosaminoglycans (amino sugars). Arterial lesions can be caused by suboptimal collagen and elastin synthesis due to three factors: 1. Vitamin C deficiency (since Vitamin C is a key building block for collagen and elastin); 2. excessive consumption of rancid fats, or heavy usage of alcohol or cigarettes; and 3. free radical damage. Once these lesions are created, the body attempts to repair them by depositing LDL cholesterol — similar to the way one would patch a tire. If that cholesterol is not oxidized, i.e. chemically changed to a harmful, unstable molecule, then this process does not create a problem. But when arterial lesions are “patched” with foam cells, arterial walls suffer page 3 page 4 even more damage, because those foam cells release free radicals which can further damage cell membranes.
Unfortunately, most people have a lot of oxidized cholesterol floating through the bloodstream. The typical American diet, with its low antioxidant intake and overconsumption of fried and overcooked foods, contributes to the overall levels of harmful oxidized cholesterol. In fact, the average American intake of antioxidants is low even by USRDA standards, making Americans particularly prone to having high levels of oxidized cholesterol.
Fortunately, there are concrete steps you can take to prevent the oxidation of cholesterol, and its subsequent ill effects on health. In addition to cutting out high-cholesterol and fatty foods, supplementation can protect existing cholesterol and all tissue cells — from oxidation. Antioxidants, substances which scavenge and neutralize free radicals, protect the cardiovascular system by halting the oxidation of cholesterol, and helping to prevent plaque accumulation in the arteries and the continual secretion of free radicals by foam cells. Supplementing the diet with high amounts of Vitamin C, a key antioxidant, also encourages a more healthy “patching” of existing lesions by using collagen (made from Vitamin C) instead of cholesterol. HEART SCIENCE contains generous amounts of the following antioxidants for their protective benefits:
The Regulating Trio
Three nutrients — Magnesium, Potassium, and Taurine — work closely together in the body to help maintain the normal electrical rhythm of the heart, promote proper fluid balance, and prevent excessive Calcium levels from building up in the heart and artery linings.
Artery Lining Protectors
Your arteries form an integral part of your cardiovascular system, carrying blood away from the heart to nourish other parts of the body. In a healthy heart, blood surges through the arteries with every beat of the heart. The arteries expand with each pulse to accommodate the flow of blood. When arteries become hardened and narrowed by the Build-Up of plaque, they can’t expand and are not able to transport blood efficiently throughout the body. This inability to open up increases blood pressure, putting a strain on the heart as well as the arteries. HEART SCIENCE includes ingredients specifically geared to protect against plaque formation within arteries and maintain the flexibility of these vital blood vessels. N-Acetyl Glucosamine (NAG) is a key amino sugar which forms the building blocks of mucopolysaccharides. Mucopolysaccharides, which are long chain sugars, are an integral component of connective tissue. They combine to form gel-like matrixes which are present throughout tissues in the body, helping to maintain the elasticity of blood vessels which must continually adapt to the changing pressures of blood flow. Each daily dose of HEART SCIENCE provides 500 mg — a substantial amount — of this vital tissue building block. There is evidence indicating that Silicon, a natural mineral, may protect against plaque formation in the arteries. Silicon is found mainly in connective tissues, where it helps bind the body’s chemical matrix. Bound Silicon is found in high amounts in arterial walls. Researchers have found that there is a steady decline in the Silicon content of the aorta and other arteries as we age. This may be due to the low fiber content of the typical American diet, since fiber is a key dietary source of Silicon.23 HEART SCIENCE includes 400 mg of Horsetail herb extract, a natural source of Silicon. Hawthorn Berry is without question the herb most widely used to encourage normal heart function. The beneficial actions of Hawthorn Berry on cardiac function have been repeatedly demonstrated in experimental studies. Supplementation with Hawthorn Berry has been shown to improve both the blood supply to the heart by dilating coronary vessels, and the metabolic processes in the heart, resulting in normal, strong contractions of the heart muscle.34 Also, Hawthorn may inhibit the angiotensen converting enzyme, which is responsible for converting angiotensen I to angiotensen II, a powerful constrictor of blood vessels.34 Bromelain, a natural enzyme derived from pineapples, has become well-known for its neuromuscular relaxing properties. Researchers have reported favorable results when using Bromelain for soothing vascular linings. Initial research also indicates that Bromelain may break down fibrin, the glue which holds platelets together to form blood clots.6
Capillaries are the smallest, yet some of the most important, blood vessels. If you think of your cardiovascular system as a series of roads which transport blood and oxygen, then your arteries are akin to interstate highways, your arterioles are the main city boulevards, and your capillaries are local residential streets. Capillaries are so small, in fact, that single red blood cells actually have to fold up to fit through them. Because of their tiny size and the intricate nature of their network throughout the body, capillaries are responsible for actually nourishing each individual tissue cell! Along the length of the capillaries are small openings called slit pores through which oxygen, glucose, and nutrients leave the capillaries and enter the surrounding interstitial fluid. From there, they cross cell membranes and nourish the cells. Similarly, the waste products of cells enter the fluid and cross over into the capillaries, where they are then transported to the liver and kidneys for disposal. If the capillary slit pores are torn or have lesions, then blood proteins and Sodium will leak out and cause the interstitial fluid to take on a more gel-like nature. This makes the transfer of oxygen and nutrients to the cells more difficult, as well as the disposal of cell waste products, turning the fluid into a stagnant swamp instead of a flowing river. In addition to its powerful antioxidant actions, Proanthodyn also helps protect collagen and elastin, the main constituents of tissue in the capillaries, and throughout the body. It is absolutely essential for capillary walls — which are only one cell thick — to be strong and stable, so that they do not allow blood proteins to leak into the interstitial fluid. Once the interstitial fluid takes on a gel-like consistency, the surrounding cells literally become starved from lack of nutrition. The exciting news is that the proanthocyanidins contained in Proanthodyn are among the few substances yet discovered which can help strengthen capillary walls, ensuring the liquid nature of the interstitial fluid.2 Plus, proanthocyanidins help keep capillary and artery walls flexible, allowing for proper blood flow to the heart.
The 1990’s mark a decade of increased awareness among Americans of important health issues. Much of the discussion has revolved around protecting that precious center of life we call the heart. Simple lifestyle change is one of the most effective ways to maintain and protect the functioning of the cardiovascular system. In order to take a holistic approach to heart care, make sure you include plenty of fresh fruits and vegetables (organic, if possible) in your diet, and cut down on fatty and cholesterol-forming foods. Reduce your salt and alcohol intake to a minimum. Try to get regular, sustained aerobic exercise for at least 30 minutes three times a week. Don’t smoke – or if you do smoke, try to eat even more fresh fruits and antioxidant-rich vegetables to counter the amount of free radicals being produced in your body. Lastly, consider adding Source Naturals HEART SCIENCE to your health regimen. HEART SCIENCE, the most comprehensive formula of its kind, provides targeted protection to the entire cardiovascular system. By approaching the promotion of normal heart function on five different levels — through the inclusion of ingredients which supply energy, decrease harmful homocysteine levels, fight cholesterol Build-Up, help regulate electrical rhythm, and protect artery and capillary linings — HEART SCIENCE is the perfect addition to a holistic approach to heart care.
Source Naturals HEART SCIENCE™