Search Term: " Silymarin "
Milk thistle shows promise in treating liver cancer
October 10, 2018 03:26 PM
When it comes to treating liver cancer, milk thistle my be the key. For yes this prickly, purple plant has been used for good liver function and is sought out for its anti inflammatory and antimicrobial qualities. This plant extracts silibinin which has anti-cancer effects on cancer cells. It also inhibits the cancer cells cycle and increases the death of cancer cells. This plant also has another compound called silymarin which is supposed to be more enriching than Vitamin E.
"New studies have shown that the protective benefits of milk thistle are far greater than conventional scientists could have ever imagined."
Read more: https://www.naturalnews.com/2018-09-16-milk-thistle-shows-promise-in-treating-liver-cancer.html
If You Want To Detox, Look To The Liver
The liver is the largest organ in the body and is responsible for processing toxins in it. This organ has been shown to have over five hundred vital functions including production of bile, metabolism of protein and carbohydrates, storing vitamins, and detoxification. This makes it very important to always detox it in order to keep it working at its best. Apart from getting rid of all the toxic substances that will have build up, here are some of the other benefits of liver cleansing.
Benefits of Liver Cleansing
Immune system support – Since the liver is responsible for the removal of toxins from the body, cleansing it makes your immune system stronger.
Supports whole body detox – As the liver removes toxic substances from the body, there are some little amounts of toxins that remains in it. With time there is buildup of too many toxins which will need you to detox it to make it work well again.
Increasing vitality - By cleansing the liver, you will have restored it to its peak working condition. This in turn will help breakdown fats thus make your skin look healthier and younger.
Weight loss – Cleansing promotes bile production which is used to break down fats. It is therefore important to detox if you want to lose weight.
How efficient your liver works depends on the constant supply of antioxidant nutrients to it. One of the major antioxidants that you can use to detoxification the liver is Glutathione. This antioxidant enzyme protects the liver cells from radical damage and also protects them from environmental damage. It also protects the liver cells from toxic substances that are produced by the body itself. Another antioxidant that has proven to be one of the most potent liver-protecting substances is Silymarin. It I responsible for the stimulation of new liver cells production and can even stimulate glutamine levels up to 35 percent. It is very important to cleanse your liver regularly to always keep it clean and realize these health benefits.
How Does Silymarin Protect the Liver?
For thousands of years, the flowering herb milk thistle has been used as a natural remedy for many different ailments, including liver problems. The herb is still widely used today – in fact, the University of Maryland Medical Center reports that several scientific studies have shown that milk thistle helps protect the liver from toxins and may provide many other benefits.
How Does Milk Thistle/Silymarin Help the Liver?
So how does this ancient Mediterranean herb help treat present-day liver disorders? The seeds of milk thistle contain Silymarin, a powerful bioflavonoid complex. Silymarin is actually comprised of three different flavonoids: silybin, silydianin and silychristin. Working together, these flavonoids provide antioxidant properties that are believed to help repair damaged liver cells by generating the growth of new ones. These reparative properties make Silymarin particularly useful at treating liver damage conditions such as cirrhosis.
For example: in a clinical trial of patients suffering from cirrhosis of the liver, some were treated with daily doses of oral Silymarin while a control group was given a placebo. After four years of treatment, the study found that those patients who were given Silymarin had a significantly higher survival rate as compared with those treated with the placebo.
In addition to supplying a concentrated boost of antioxidants, Silymarin also has anti-inflammation properties which may be helpful in treating hepatitis or general liver inflammation.
How to Take Silymarin
Once Silymarin is extracted from milk thistle seeds, it may be taken in a few different forms: Capsule, Liquid form, and Silymarin phosphatidylcholine complex.
The silynmarin phosphatidylcholine complex may offer added liver protection benefits. Studies have shown that it may be easier for the body to absorb than the form from ordinary milk thistle seed extract. This is because phosphatidylcholine helps the Silymarin attach to cell membranes, which may block harmful toxins from entering the liver.
What are the Health Benefits of Andrographis?
June 20, 2012 08:30 AM
Being highly cultivated in the Southern parts of Asia, Andrographis is a herb which is widely used in the treatment of a wide range of diseases and infections as well. It was what was used as an antibiotic before the real drugs were created. The main parts which are used are the leaves and roots. All parts of this plant taste bitter.
In ancient times, the herb was vastly used to treat the flu, common cold, upper respiratory infections and a number of diseases which were highly infectious. Traditionally, it is used to treat a number of ailments like diarrhoea, cholera, pneumonia, leprosy, sore throats, ear infections and even chicken pox among many others. Andrographis has also replaced quinine and is mostly used to treat malaria.
This herb has proved advantageous as it poses immunity fighting capabilities as it stimulates a person's immune system. Scientific research has recently shown that the herb has the ability to hinder the multiplication of cancerous cells in a person's body.
Apart from all those, this medicinal plant has more health benefits to the human body. First of all, its action is mainly based on the andrographolides contained in it which help in backing up the immune system. It does so in a number of ways including; production of the white blood cells which fight against disease causing organisms, it plays a big part in the release of interferon and it also enhances a healthy lymphatic system which functions to the maximum.
The herb is also believed to aid in the fight of HIV and Aids as it supports a person's immune system which is often weaken by the disease.
Andrographis has an anti-inflammatory quality and is therefore used in the treatment of associated symptoms as well as a pain reliever. Swollen lymph nodes, muscular pain and medical conditions like arthritis, rheumatism and many others which result to intense pain can be treated by this herb.
Treats Liver issues
With this herb, you can benefit from effective treatment of liver problems such as jaundice, hepatitis and also conditions caused as a result of drug abuse by an individual. This is because it has been noted to act as Silymarin which helps in the protection of the liver.
Currently, scientific studies have also shown that Andrographis helps to stop the formation of blood clots and thus it can be used to treat diseases like atherosclerosis and prevent heart attacks. It also helps in the prevention of conditions like re-clogging which could lead to the congestion of arteries after treatment.
Diabetic individuals may also benefit vastly from this herb as it poses antioxidant properties which aid in blood sugar regulation. It does this by reducing the concentration of a person's blood sugar.
There are supplements of this herb available in the market today. If you want to experience the benefits yourself, you can start by purchasing them and take them as directed. Andrographis is surely a good way to lead a healthy life free from a variety of common and complicated diseases.
What Is Silymarin And What Are Its Health Benefits?
April 11, 2012 07:29 AM
Silymarin a Component of Milk thistle
Silymarin refers to a dietary supplement that is derived from the seeds of the milk thistle plant, whose scientific name is Silybum marianum. Milk thistle is native to Southern Europe, Middle East and North Africa, but it has also been naturalized in North America. The name of the plant is derived from the white, milky sap from its leaves and stems once they have been broken. Silymarin is made up of three types of plant flavonoids, namely silibinin, silicristin and silidianin. These work together as Silymarin, providing several health benefits to people. The medicinal benefits of Silymarin are not a recent discovery, since extracts of the milk thistle have been used for centuries in the treatment of liver diseases. Currently however, the benefits of Silymarin are not restricted to the treatment of liver conditions. With time, it has emerged that Silymarin has other health benefits, which will be discussed in this article.
One of the best known health benefits of Silymarin is its protection of the liver against toxins. The liver is one of the most important organs in a person's body, aiding in food digestion in addition to cleaning toxic substances from the blood. This means that the diseases that affect a person's liver will also affect his or her overall health. One of the most serious diseases that affect the liver is hepatitis, a viral infection that causes liver inflammation. Research has shown that Silymarin inhibits the development of the hepatitis virus, since it has antioxidant and anti-inflammatory properties. It also stimulates the body's immune system, providing overall liver protection.
Silymarin also has anticancer benefits, owing to its antioxidant properties. Antioxidants normally prevent the damage of healthy body cells by free radicals. According to the American Cancer Society, the antioxidant properties in Silymarin offer protection against skin cancer. Further, Silymarin also helps to reduce the growth of prostrate, breast and cervical cancer cells. This means that when used together with other cancer treatments, it can actually help to prevent or reduce a patient's need for chemotherapy. It is also useful in the treatment of cancer, due to the fact that it protects the liver from the toxins in the chemotherapy drugs.
Other than chemotherapy drugs, Silymarin also protects the liver against any other drugs that may affect the liver, as well as harmful substances such as alcohol. In some parts of Europe, milk thistle is normally given to patients whose medications are known to cause liver complications. The other benefit of Silymarin is that is helpful on controlling the blood sugar levels. In a study involving patients with type II diabetes, it was found that taking Silymarin at least thrice a day significantly reduced their blood sugar levels. In addition, the patients also experienced a drop in the levels of bad cholesterol.
Silymarin has no toxic compounds, so it is safe to use without any serious side effects. The only side effects that have been reported are indigestion, diarrhea and allergic reactions. However, the prevalence of such occurrences is negligible, as they only apply to few people. Nevertheless, people with existing medical conditions should consult their doctors prior to taking Silymarin.
What Herbs Cleanse The Liver?
March 14, 2012 08:21 AM
A liver cleanse is something everyone should do every now and then. Do not wait to be told by a doctor or worse wait for a diagnosis that something is wrong with your liver. You can do it as a prevention or simply because it is good for the body. A liver cleanse plus a lifestyle change can prevent irreversible liver damage.
Important Facts about Your Liver
1.The liver is one of the most important organs in the human body.
2. Its main purpose is to filter blood that comes from the digestive system before it is delivered to the rest of the body.
3. It is responsible for detoxifying chemicals and is the organ responsible for drug metabolism.
4. It produces substances that play an important role in blood clotting.
5. This organ is considered the biggest solid organ in the body. It consists of two sections, a right and a left lobe.
6. The liver along with organs that sit under it such as the gallbladder, parts of the intestines and pancreas work hand in hand in the digestion, absorption and processing of food.
7. It works in saturated fat breakdown.
In North America alone, liver cirrhosis is the 12th most common cause of death. What happens is that normal tissues are overtaken by scar tissues mainly due to alcoholism. This scarring in the liver may also be caused by conditions such as hepatitis, toxins, and fatty liver. Too much scarring will cause your liver to malfunction. A liver transplant may be required in severe cases.
A fatty liver is the result of fat overwhelming the organ. This causes inflammation and disturbs the proper functioning of the organ. If not treated immediately, a fatty liver may progress to cirrhosis and liver failure. Again alcoholism is a big contributing factor to this condition. Other contributing factors are obesity, metabolism problems, some medicines and gastric bypass surgery. A fatty liver also increases the risk of developing type II diabetes.
Protecting the liver
There are ways to keep your liver healthy and protect it from liver damage. Do not abuse alcohol, eat a healthy diet, and stay within the range of your ideal weight. A liver cleanse on a regular basis is also a good way to take care of your liver.
These are some of the herbs that are said to be highly effective in a liver cleanse: Milk Thistle - it helps detoxify the liver and decrease the damage caused by alcohol abuse and some medications. It contains Silymarin which is a strong antioxidant. This antioxidant helps to restore liver cells. It protects the gallbladder and the liver from toxins and free radicals which may cause cancer.
Turmeric - it flushes out toxins and soothes digestive disorders. It contains curcumin which is also a strong antioxidant.
Dandelion Root - used to detoxify, cleanse, strengthen and tone the liver. It helps to promote the flow of bile and excess water removal. It contains high levels of potassium which is essential in regulating the water balance in the body.
Although these natural methods of liver cleanse are highly recommended, it is still important that you consult your physician before you start using them.
You can protect your liver and more with Milk thistle Extract
December 23, 2010 09:48 PM
Milk Thistle Benefits
Milk thistle has been used to treat liver problems for centuries. Its Latin name is Silybum marianum which explains the name of its main flavanoid complex, Silymarin, which is obtained from the seeds. Milk thistle offers both a regenerative and a boosting effect to the liver, improving its effect on toxins while enabling it to recover from damage caused by cirrhosis, hepatitis and the effect of toxins and drugs.
Milk thistle also helps to reduce the cholesterol content of the blood and to improve the generation of glutathione, the body's master-antioxidant. Many studies have shown that milk thistle enables patients to survive longer after life-threatening liver conditions such as cirrhosis, and also protects it from the effects of sustained use of common drugs such as acetaminophen (Tylenol and Paracetamol) that progressively damages liver cells, and also of many antipsychotics and antibiotics that have a similar effect.
There are no doubts that taking milk thistle does your liver a great deal of good and leaves it in a much healthier state than it found it.
Milk Thistle and Painkillers
Over the counter painkillers such as Tylenol and paracetamol are based upon a chemical known as acetominophen. Milk thistle can be used to reverse the damage that acetaminophen can cause to your liver if you catch it early enough. Here is how this form of painkiller can cause damage to your liver.
Acetaminophen undergoes processes known as sulfation and glucuronidation prior to being excreted from the body. This process is not harmful to the liver, and is a normal biochemical means of removing excess acetominophen from your body after it has done its work. However, if you have taken excess acetaminophen (>4g/day or 8x 500mg tablets) there is too much for the above process to handle, and a secondary biochemical route (the cytochrome p-450 system) is taken that generates an intermediate product known as NAPQI.
Normally, this NAPQI is safely metabolized by the antioxidant glutathione but if there is insufficient glutathione in your system then the NAPQI will destroy cells in your liver. That can occur if too much acetaminophen has been taken for the glutathione to handle, if alcohol is also involved or if the diet of the patient is nutritionally deficient. If left untreated this condition can be resolved only by a liver transplant, without which it is usually fatal. Milk thistle can help to repair this damage and survival is more likely with patients who take milk thistle than those that do not.
So if you take acetaminophen or drink alcohol on a regular basis, or you just want to protect your liver, what is stopping you from taking milk thistle?
Milk Thistle And Silymarin
August 12, 2009 12:44 PM
In Europe, milk thistle was used as a well-known remedy for liver problems and also as a digestive aid. Pliny the Elder, the early Roman writer, explained how the juice of milk thistle mixed with honey was used for carrying off bile. Gerard, an herbalist, said in 1597 that milk thistle was one of the best remedies for liver-related diseases. Milk thistle was also given to nursing mothers to improve milk production.
The liver is an extremely important organ that is found in the body. It is responsible for filtering toxic material from the body, which prevents accumulation that can lead to disease and death. Often, the vital functions of the liver are overlooked. Nevertheless, they are extremely important. It is essential to keep the liver working properly. Milk thistle has been proven to be very beneficial for liver function. Milk thistle extract has been shown in observations to help reverse both acute and chronic liver problems, including cirrhosis and viral hepatitis. The antioxidant properties may be due to the bioflavonoid content. Milk thistle has also been found to help heal the liver from damage that occurs from alcohol toxicity. It has been used to treat many different liver ailments. Among these are fatty liver disorders, chronic hepatitis, inflammation of the bile duct, hardening of the liver, and cirrhosis. Milk thistle is also thought to actually help liver regeneration when part of the liver is removed.
Milk thistle possesses a variety of compounds which are known as Silymarin. This includes silybin, silydianin, and silychristin. All of these substances are known to protect the liver against some toxins, which helps to increase the function of this important organ. Silybin is used as an antidote to the deathcape mushroom, which is known to destroy liver cells. The deathcap species is one of the most toxic of liver poisons and has a death rate of up to fifty percent. A study with sixty patients suffering from deathcap poisoning treated with silybin produced incredible results. None of the participants died. Silymarin is an effective remedy if it is administered within forty-eight hours of ingestion. This compound seems to occupy the receptor sites to protect the cell membranes. Not only does it work to treat serious liver conditions, but it also prevents damage from occurring. Silymarin contains amines which are known to help stimulate the production and flow of bile. This compound has been found in studies to work exclusively on the kidneys and liver. Milk thistle has also been shown to stimulate the synthesis of protein.
The seeds of the milk thistle plant are used to provide alterative, antioxidant, galactagogue, hepatic, and stimulant properties. The primary nutrients found in this herb are bioflavonoids. Primarily, milk thistle is extremely beneficial in treating cirrhosis, hepatitis, jaundice, kidney problems, and liver disorders. Additionally, this herb is very helpful in dealing with alcoholism, appetite loss, high blood pressure, boils, chemotherapy, depression, epilepsy, fatty deposits, gas, heartburn, heart problems, hemorrhages, hypoglycemia, indigestion, absent lactation, menstrual symptoms, effects of radiation, skin diseases, varicose veins, and the effects of toxins.
BerryOxidants - Food-Sourced Antioxidant Protection
April 12, 2009 11:07 AM
BerryOxidants - Food-Sourced Antioxidant Protection
2 tablets contain:
Vitamin C (as ascorbic acid) 1,000 mg
Grape Seed Extract (Proanthodyn™) 150 mg
Green Tea Leaf Ext (95% polyphenols, 150 mg 35% ECGC)
Turmeric Rhizome Ext (95% curcumin) 150 mg
Polygonum cuspidatum Root Ex 100 mg (8% total resveratrols)
Bromelain 100 mg
Quercetin 100 mg
Ginkgo Leaf Extract (50:1) 60 mg
Silymarin (from milk thistle seed ext) 60 mg
Hawthorn Berry Extract (4:1) 50 mg
Rosemary Leaf Extract (5:1) 50 mg
Citrus Bioflavonoids 50 mg
Lecithin 50 mg
Grape Skin Extract (20% polyphenols) 50 mg
Astragalus Root Extract (10:1) 50 mg
Cabbage Floret & Stem 50 mg
Cranberry Fruit Ext (90% solids) 50 mg
Sweet Cherry Fruit Ext (10:1) 50 mg
Holy Basil Leaf Ext (2% ursolic acid) 50 mg
Olive Leaf Ext (15% oleuropein) 40 mg
Rutin 40 mg
Lycium Fruit Extract (4:1) 40 mg
Strawberry Fruit 40 mg
Açai Fruit Juice Powder 40 mg
Organic Amla Fruit 40 mg
Pomegranate Seed Ext (40% elagitannins) 20 mg
European Elder Berry Ext (5% flavones) 20 mg
Mangosteen Fruit Rind Extract 20 mg (standardized to 95% flavonoids & 40% mangostins)
Raspberry Leaf Ext (40% elagitannins) 10 mg
White Mulberry Fruit Ext (10:1) 10 mg
Blueberry Leaf Ext (20% chlorogenic acid) 10 mg
Bilberry Fruit Ext (25% anthocyanidins) 5 mg
Lower Blood Sugar
October 16, 2008 01:54 PM
Many people struggle to control their weight. However, while they are going on and off various diets, they fail to realize that they are also struggling to control blood sugar. Actually, the cause of blood-sugar problems may be weight problems, as being overweight and having blood sugar problems tend to go hand in hand. Too many blood sugar swings during the day tend to increase hunger jags, snacking, and overeating. When you overeat, you’re much more likely to add on the pounds, setting the stage for obesity, pre-diabetes, and full blown diabetes.
Sadly, both pre-diabetes and overweight have become modern epidemics that are out of control, with two of every three Americans being overweight and over 100 million people having some signs of pre-diabetes. Both of these illnesses are nutritional disorders that result from eating too many unhealthful foods. However, there is good news: you can reverse pre-diabetes and control your weight.
One can self-diagnose pre-diabetes by looking for the most visible symptom: being chubby or fat around the waist. Other clues are cravings sweets and starchy foods, not being hungry at breakfast, and feeling tired or mentally fuzzy after lunch. Many physicians diagnose pre-diabetes when a patient’s fasting blood sugar falls between 100 and 124 mg/dl. There are several dietary factors that significantly increase the risk of overweight. Some of these being: too many calories, too many refined carbs, especially sugars, and too many unhealthful oils.
The average woman needs about 1,600 calories and the typical man needs about 2,000 calories daily, but the average American now consumes 3,900 calories each day, making it difficult to burn off all these calories and causing the accumulation of body fat. Because most excess calories take form of refined carbs and sugars, which are digested rapidly, rapid or extreme spikes in blood sugar levels, elevated insulin levels, and bouts of hunger result, which stimulate low blood sugar. Trans fats, which are found in partially hydrogenated vegetable oils, interfere with the body’s processing of fats and often lead to weight gain. Most of these problematic calories are found in fast foods, microwave foods, and other types of convenience foods, which are all best if they are avoided.
Even though pre-diabetes can be scary, it’s actually an opportunity to improve your eating habits and regain your health. To improve your health you can emphasize quality protein, emphasize high-fiber vegetables and fruits, include grapefruit in your diet, use more vinegar, and add some cinnamon. Since protein stabilizes and safely lowers blood sugar levels, be sure to start each day with some protein with breakfast and eat a little protein with each meal.
Most veggies and fruits are rich in fiber, which helps to lower blood sugar, so opt for salads and steamed broccoli while avoiding crutons, potatoes, bananas, and pears. Despite the calories, eating fresh grapefruit can help in weight reduction. The acetic acid in vinegar can also help to improve blood sugar and insulin levels, reduce appetite, and help with weight loss. Adding cinnamon has also been shown to reduce blood sugar levels. There are also several supplements that have exceptional value in improving insulin function or lowering blood sugar levels. These include lipoic acid, chromium, Silymarin, omega-3 fish oils, vitamin D, and Pycnogenol.
You can also enhance the benefits of diet and supplements by increasing your physical activity as it helps build muscle and burn blood sugar and fat. Tackling pre-diabetes can not only reduce your long-term risk for health problems, such as heart disease and Alzheimer’s disease, but also can allow you to quickly gain more energy and feel less post-meal fatigue.
Control Blood Sugar Naturally
October 01, 2008 12:10 PM
Your blood glucose level is generally controlled by insulin and glucagons, both of which are biosynthesized in the pancreas. Insulin works by making the glucose bioavailable to the mitochondria to convert into energy, while glucagon, the lesser known of this twosome, stabilizes the level of insulin and mobilizes it to do its job. There are two types of diabetes, known as Type I and Type II or A and B.
Type I diabetes, also known as juvenile onset diabetes, is an autoimmune condition in which the immune system destroys Beta cells because they are recognized as being foreign. It is the Beta cells that generate insulin, and so the condition can be fatal. Patients with Type I diabetes must take insulin throughout their lives, and while potential cures are currently under investigation, none are yet available. Although insulin can be effective it does not guarantee survival, and a better form of treatment is required.
Type II diabetes is by far the more common of the two, and is a form of resistance to insulin, where the body cells cannot use insulin properly. The pancreas initially reacts to this by producing more insulin in response to the increased blood glucose level, but through time it loses its ability to produce insulin as a reaction to an increase in blood sugar, even though this occurs as a result of digesting a meal.
The exact causes of either type of diabetes are not known for sure, although the general mechanism by which they work is known. However, Type II diabetes is believed to be due to some form of interaction between genetics and environment, and it is known that the majority of Type II sufferers are obese and also over 40.
The treatment for this type of diabetes is rarely insulin, but a controlled diet, control of your cholesterol level and blood pressure, exercise and specific medicines designed for sufferers of this form of diabetes. However, there are also natural supplements that can be used to control your blood sugar levels. Diabetes was the sixth leading cause of death of the USA in 1999, with 450,000 deaths, and by 2005 had reached about 300 million sufferers world wide. It is therefore a serious and widespread condition, though Type II is less serious than Type I.
It is important to do what you can to control your diabetes, since after several years it can lead to problems with your nerves, eyes, kidneys and gums, and can also lead to heart disease. With diabetes you are at least twice as likely to have a stroke or heart problem as those without it, although you can reduce the risk of this by keeping your blood pressure under control, and the levels of fats in your blood to a minimum. Stopping smoking helps, and there are some natural treatments that can also help you control your diabetes.
The most important means of control is to reduce your blood sugar levels. While there are natural products that will help you to do that, do not stop taking the medication prescribed by your doctor, but use these in addition to what you are already taking. Among specific substances that can help are:
Chromium: chromium helps your body to use insulin properly. When taken in the form of chromium picolinate, it helps to replace chromium that diabetics appear to be short of. Human studies have indicated that chromium can decrease insulin levels and improve the metabolism of blood sugar in those with Type II diabetes. Some claim that chromium is harmful to health, but the general opinion is that it helps, though you should consult your doctor before using it.
Cinnamon: If you take cinnamon daily, your blood sugar levels should gradually decrease. It appears to enable your cells to make better use of the insulin your blood, although there still discussion as to the mechanism by which this occurs and of the active ingredient in cinnamon that promotes it. Some claim it to be a flavonoid known as methylhydroxychalcone polymer, or MHCP. However, others claim it not to be MHCP, but polyphenol type-A polymer. Whichever it is, many people are finding cinnamon to be effective in reducing high levels of blood sugar to a more manageable level.
Milk Thistle: It is known that antioxidants can help to control blood sugar, and the flavolignins in Silymarin marianum, an herbal extract available from milk thistle seeds, work in this manner. It is also good for protecting the liver from toxins. Although it is not clear how it is done, Silymarin appears to help to control Type II diabetes possibly by way of liver digestion of sugars in the blood. The liver processed glucose and improving its function through the consumption of milk thistle could help reduce blood sugar as well. Mulberry: The Chinese make what is known as “sugar control herbal tea” from mulberry leaves, green tea and jasmine. Mulberry leaves contain adenine, pectin and choline, and also high levels of Vitamins A and B types. This tea is used by the Chinese to control blood sugar levels, which might occur through the antioxidant effect of the mulberry constituents.
Salacia oblonga: This is an herb used in India and Sri Lanka that appears to cause a dramatic drop in the levels of insulin and sugar in the blood. It binds to enzymes in the intestine that break carbohydrates down into sugars, and so reduces the amount of sugar in your blood. That in turn reduces the amount of insulin released by the pancreas.
Apple Cider Vinegar: There is evidence that apple cider vinegar can help to control your blood sugar levels if taken before a meal. Just two tablespoons appears sufficient to give a noticeable result. This is one of those home remedies that might be just anecdotal, but might also work, so is worth trying.
Zinc: It has been discovered that diabetics suffer a deficiency in zinc. This mineral plays a part in the storage and production of insulin in your body, and a deficiency could cause an increase in your sugar level. Oysters, pecans, almonds, lamb and chicken are all good sources of zinc.
Glyconutrient complexes: we know that diabetes is an autoimmune disease for type I individuals. Supporting a properly function immune system requires a good diet as well as a diet rich in Glyconutrients. The polysaccharides found in glyconutrient formulas can help the immune system communicate better with the body and just possibly correct some autoimmune diseases which attach our cells.
These are the natural supplements that people are taking to help control their blood sugar and diabetes. It is important that you take nothing that interferes with the medicines given to you by your physician, so you should let your doctor know of any natural supplement that you are using in addition to your prescription medicines. However, it is possible to control your blood sugar with natural supplements, and those mentioned above are just a few of the natural substances available that can help diabetics control their condition and so avoid the side effects.
Milk Thistle May Help With Cirrhosis, Gallstones, and Hepatitis Liver Problems
November 14, 2007 12:34 PM
Milk thistle, botanically Silybum Adans, is a member of the daisy family that is native to the Mediterranean, the Middle East and North Africa but has also been introduced to California and parts of the eastern side of the USA, and can help with problems such as cirrhosis, gallstones and hepatitis. Although it has been recorded as being used in medieval times as a tonic for the liver, it is only relatively recently that its chemical components have been investigated. Analysis indicated the presence of hitherto unknown flavonoids which were given the name of Silymarin. In general, flavonoids are strong antioxidants found in many fruits and vegetables that eat up the free radicals that cause so much damage to our bodies.
Free radicals are very unstable molecules that are generated through pollution, such as smoking, car fumes, perticides etc, and that destroy body cells accelerating aging. They also oxidise the low density lipids (LDL) that carry water-insoluble cholesterol through the blood to the arteries where it is needed to repair damage, resulting in excess deposition and the atherosclerosis that can cause strokes and heart disease.
Antioxidants mop these up like a sponge, and are some of the healthiest types of molecules that we can consume. The Silymarin group of flavonoids are particularly attracted to the liver where they act as antihepatoxic agents that prevent the liver from becoming poisoned. But why should the liver be poisoned I can hear you ask, and what are the poisons involved? Can we avoid them? It is a very relevant question, and one that will make you wonder, every time you leave your home, especially if you live in a big city or an industrialized area.
Smoking cigarettes, working with volatile organic compounds that you can breathe in, such as paint and printing ink solvents, the exhaust fumes of cars and diesel engines, factory chimneys belching out tons of smoke, analgesics such as paracetamol, pesticides on your fruit and vegetables that you have failed to wash off, alcohol, etc, etc, etc…
All of these have to be removed from your body or you will die, awash with all these poisons that you have ingested, some deliberately and some not. The organ that does this is your liver: the powerhouse chemical plant of your body that carries out millions of biochemical reactions every day. Your liver converts all of these poisons into molecules that can be flushed away through your body naturally. However it places great stresses upon it, and even your liver needs a rest sometimes, or even just a little rejuvenating tonic would keep it happy.
Milk thistle has been used for just that purpose, especially when the liver has been toxified with excess alcohol, pesticide poisoning or even hepatitis. The Silymarin initially coats the cells of the liver by binding to the cell membranes of the cell walls, so that the toxins are hindered from entering the cells. Its antioxidant properties then neutralise any free radicals present that are causing the damage to the liver cells.
It also helps to stimulate the production of proteins to help the healing process, and reduces the fibrosis that is the development of fibrous masses outside the liver cells caused by damaged cells excreting materials such as collagens outside the cells into the general body of the liver. Finally, milk thistle helps to prevent the activity of the immune system in causing inflammation of the damaged cells.
Silymarin acts very specifically on the liver, and is often used by physicians in the treatment of such liver conditions as jaundice, hepatitis, liver cancer and cirrhosis. In addition to its own effects it appears that it stimulates the production of glutathione that is also a very powerful natural tripeptide antioxidant produced by the body when it is under oxidative stress. Its effect on cancer and some diseases is not curative, but to allow the liver to continue to detoxify the body when otherwise it might fail and lead to toxicity problems from which the patient might not be able to recover.
Due to the remarkable regenerative powers of the liver, milk thistle is able to stimulate it into repairing its damage and grow fresh cells to replace the damaged ones. This is the reason for its effectiveness in otherwise very serious degenerative diseases. It is often prescribed by doctors for patients who are taking a number of different medications. Which help the liver to metabolize these medications, since without it, it might struggle to provide the true efficacy of the prescribed drugs.
So far we have been concentrating on the liver, but milk thistle has other properties not connected directly with the hepatic function. It can help to promote the production of bile in the gall bladder and so give the digestive system a boost when needed, where it also acts as a mild laxative. However, it can also help patients suffering from both lose stools and constipation due its effect. It can also help to relieve gallstones, though medical tests are generally carried out first to ensure that they are not too large for the milk thistle to handle.
It is also an anti-inflammatory, and is useful in the treatment of acne and other inflammatory responses, and also for inflammations in the gall bladder, kidney and bladder. There are few serious side effects, although, as milk thistle rids the body of toxins, these toxins can cause problems such as diarrhea, headaches and abdominal pain. Keep in mind that you are releasing poisons from the liver into your system so that they can be expelled by the usual means, and they will put up a fight along the way. However, the milk thistle will usually win in the end.
There currently appear to be no long term issues with taking milk thistle as a supplement over a long period, and it is good way to maintain a healthy liver. Keep in mind that the liver is the body’s chemical plant, where most of the biochemical reactions of life take place, and without we cannot survive. It makes sense, therefore, to look after your liver, and milk thistle is one way of doing that; some would say the best way.
So remember that, although milk thistle may help with cirrhosis, gallstones and hepatitis liver problems, you should be prepared for a short struggle before it wins the day. Always consult your family physician for a clear diagnosis before self prescribing herbs as treatment. Your physician can advise you as the correct course of action to take once diagnosed with a liver blood test first. But, to boost overall health and wellness milk thistle is a great herbal supplement to take on a daily basis.
Complete Liver Cleanse
April 19, 2007 04:17 PM
Complete Liver Cleanse
Technical Data Sheet
The liver performs over 500 functions, including metabolizing carbohydrates and proteins, synthesizing and storing vitamins, and regulating hormones – naming just a few. To do this job, the liver is also required to be exposed to potentially harmful toxins and chemicals, every day.
One way to support the liver is through periodic supplementation with the proper balance of herbal ingredients, phytosterols, and fiber. Complete Liver Cleanse is a convenient, multi-ingredient formula that supports overall liver health and detoxification.
Complete Liver Cleanse:
Includes ingredients for various aspects of liver and gallbladder support:
-Herbal ingredients that support liver and gallbladder health
-Detoxifying ingredients that keep bound toxins from being reabsorbed
-Phytosterols to block cholesterol absorption in the intestines
-Fiber that moves cholesterol and toxins out of the body
-Oat beta-glucan fiber with up to 4 times higher viscosity than other beta-glucan
-Simple, two week liver cleanse program
Each 3 capsules contain:
Calcium (as calcium D-glucarate) 13 mg
Proprietary PuraFiber Blend: 1 mg
Viscofiber Oat B-Gucan Concentrate, phytosterols
(beta sitosterol, campesterol, stigmasterol, brassicasterol,
and other plant sterols), and glucomannan
Milk Thistle (Silybum marianum) Fruit Phytosome 220 mg
One part Milk Thistle Extract, standardized to contain 80%
Silymarin bound to two parts phosphatidylcholine (soy) using
a patented process
Burdock (Arctium lappa) Root Extract 4:1 100 mg
Calcium D-Glucarate 100 mg
Boldo (Peumus boldus) Leaf Extract 2:1 75 mg
Turmeric (Curcuma longa) Rhizome Extract 50 mg
Standardized to contain 90% curcuminoids
Dandelion (Taraxacum offinale) Root Extract 4:1 50 mg
Artichoke (Cynara scolymus) Leaf Extract 30 mg
Standardized to contain 13-18% caffeylquinic
Acids calculated as chlorogenic acid
Contains no: sugar, salt, yeast, wheat, dairy products, artificial coloring, artificial flavoring, ingredients of animal origin, or preservatives. This product contains natural ingredients; color variations are normal.
Other ingredients: See label for most current information
Viscofiber is a registered trademark of Cebena Bioproducts, Inc. The use and composition of the Viscofiber proprietary formula is protected by patients and patent applications filed in the
This product contains calcium D-glucarate, the use of which is licensed from Applied Food Sciences, LLC, and protected by
HOW DOES IT WORK?
Every day, the liver must process an almost unbelievable amount of blood – at a rate of three pints every minute. All the while, the liver performs over 500 physiologic functions, including protein and glucose synthesis, carbohydrate metabolism, vitamin and mineral storage, synthesis of clotting factors, urea formation, metabolism of medications, and the production of bile. The liver also assists in hormonal regulation, blood glucose control, and other regulatory functions.
Harmful substances that have been neutralized by the liver are carried to the intestines and kidneys for excretion. They are transported by bile, a greenish, watery solution that is synthesized, and continuously being excreted, by the liver. Stored in the gallbladder, a small sac cupped in the under surface of the liver, bile is also required for the digestion of dietary fats. However, in the case of toxins, bile is primarily an early transporter of the toxic compounds to the intestines, where they can be bound to fiber that helps transport them out of the body. Environmental toxins, including lipid (fat) soluble toxins, are broken into water-soluble components by bile to be excreted through the kidneys or colon.
Detoxification refers to the process of excreting potentially harmful compounds that are both generated by the body and acquired through exposure to the environment. In the body, toxins are generated as by-products of cellular metabolic processes. Examples include dead and digested bacteria, hydrogen peroxide, cellular debris, and carbon dioxide.
The Environmental Protection Agency has determined that the amount of environmental toxins in the air, groundwater, and soil has increased significantly in the last 40 years. In fact, the use of pesticides has doubled every ten years since 1945. Americans are increasingly exposed to heavy metals, pesticides, fossil fuel emissions, sulfur oxides, hydrocarbons, and other harmful chemicals. The Environmental Protection Agency reports that traces of toxic chemicals can now be found in nearly every American.
Herbal Liver Support
One of the major components in Complete Liver Cleanse is its milk thistle extract, standardized to contain 80% Silymarin, the plant’s most bioactive compound. Milk Thistle provides support, at a cellular level, for healthy liver function. A patented delivery system, known as the Phytosome process, provides superior absorption of the milk thistle extract.
Silymarin, a key compound found in milk thistle, is a mixture of flavonoids with a long history of liver support. Silymarin supports the health of Kupffer cells, specialized liver cells responsible for removing bacteria, old blood cells, and other foreign matter from the liver’s blood supply. Silymarin scavenges free radicals (superoxide anion radical and nitric oxide) produced by activated Kupffer cells, supports healthy leukotriene levels, and supports glutathione production that is used in detoxification.
Silymarin also supports the health of hepatocytes, highly versatile liver cells with unique physiologic functions. Studies of Silymarin have demonstrated that it supports the health of the hepatocyte outer membrane, which is crucial to the liver’s detoxification processes. Silymarin also supports the healthy regenerative ability of the liver through support of protein synthesis in the hepatocytes.
A special, patented proves known as Phytosome enhances the absorption of milk thistle in Complete Liver Cleanse. The Phytosome process pairs herbal ingredients with phosphatidylcholine molecules. Phosphatidylcholine is a naturally occurring substance found in soybeans, egg yolks, and some vegetables. In the body, phosphatidylcholine is an important building block of cell membranes.
When milk thistle (or other herbs) are bound with phosphatidylcholine, the phosphatidylcholine molecule facilitates absorption through the intestines into the bloodstream. Research has shown increased blood and serum levels for phytosome herbs in comparison to the individual herb alone.
To test whether binding an herb with phosphatidylcholine increased its bioavailability, researchers gave volunteers identical amounts of either milk thistle alone, or milk thistle phytosome. The researchers then took blood sample from the participants and measured the level of silybin (a key compound in milk thistle). The measurements showed that silybin levels in participants taking the phytosome form of milk thistle were higher, and that silybin was detected for a longer time, than those who took milk thistle without the phytosome delivery system.
Other Herbal Liver Supportive Ingredients
Herbal extracts are often at their best when they are working synergistically – that is, when different constituents of each plant work together and support each other. Complete Liver Cleanse contains a variety of herbal extracts that have noted benefits for supporting the body’s healthy bile flow and free-radical scavenging effects. These ingredients provide a wide spectrum of liver supportive benefits.
For instance, dandelion root extract supports healthy bile flow from the gallbladder.
Burdock is originally native to Europe and Asia, but was introduced to
Burdock root (Arctium lappa) supports the natural physiologic processes of organs involved in detoxification and elimination: notably, the liver, kidneys, and intestines.
Bolodo (pemus boldus) is a small evergreen native to South America, but naturalized to southern
In scientific studies, boldo appears to have strong free-radical scavenging ability, mostly attributed to the catechin and flavonoids content of its leaves. In a clinical study, boldo also appears to relax smooth muscle and support intestinal transit time.
Artichoke Leaf extract specifically supports healthy bile production in the liver and healthy gastrointestinal function in general. Research into artichoke’s gastrointestinal supportive properties has included at least three clinical trials. Artichoke’s role in supporting healthy cholesterol levels within normal limits has also been investigated.
Turmeric (Curcuma longa) is a perennial shrub native to southern
More recently, turmeric has been investigated for its support of healthy bile secretion, and pancreatic and gastric function.
In a scientific study, dietary curcuminoids derived from turmeric supported healthy lipid metabolism and cholesterol levels already within normal limits.
Curcumin has also been shown in scientific studies to enhance the activity of glutathione S-transferase - an enzyme responsible for linking glutathione (one of the body’s natural antioxidants) with toxins to help remove them from the body. In this way, it provides additional support for healthy liver function.
The process of detoxification is the breakdown and excretion of substances that are no longer needed or may be harmful to the body. One of the ways in which the body excretes hormones and toxins is by binding them to glucuronic acid in the liver, and then excreting this compound in the bile.
However, this process can be disrupted by B-glucuronidase, an enzyme that is produced by intestinal bacteria. This enzyme has the ability to break (uncouple) the chemical bond established by glucuronic acid. This action releases the bound toxins, which are then reabsorbed into the body instead of being excreted.
Calcium D-Glucarate is the calcium salt of d-glucaric acid. It is found in both the human body, and in some plant sources, including broccoli and oranges.
Calcium d0glucarate enhances the body’s detoxification systems by inhibiting the actions of beta-glucuronidase. This helps decrease the portion of active compounds that could be hazardous to the body.
Cholesterol is a waxy, fat-like substance that is vital to fat digestion, cell structure, nerve insulation and hormone production. Cholesterol comes from two sources: dietary or “exogenous” cholesterol absorbed in the intestine, and “endogenous” cholesterol formed mostly by the liver and stored in the gallbladder.
Cholesterol occurs in two forms known as lipoproteins. Lipoproteins act as transports that carry fat s to and from the cells.
High-density lipoprotein (HDL) carries low lipid density cholesterol (LDL) away from arterial walls and returns it to the bloodstream. LDL then travels back to the liver, which processes and eliminates it. While high levels of HDL cholesterol is desirable, high amounts of LDL cholesterol is not supportive of optimal health.
LDL-cholesterol is both synthesized in the body, or absorbed into the bloodstream through receptor sites in the intestines. Think of these receptors as “parking spaces” for cholesterol. As it happens, the liver can receive up to 500 mg per day of cholesterol from intestinal absorption. (It can also produce as much as 1000 mg per day).
One way to help reduce the absorption of LDL cholesterol molecules it to occupy their “parking places” in the intestines. Phytosterols in Liver Cleanse are essentially the “fat” of plants. They’re found in nuts, corn and rice and are some of the “good” fats associated with the benefits of olive oil, flaxseed oil and other healthy oils.
The structure of phytosterols is so similar to cholesterol that they fit perfectly in the specially-shaped intestinal parking spaces that LDL-cholesterol would normally occupy.
Taken with, or just before meals, phytosterols block the cholesterol receptor sites so that cholesterol is excreted from the body rather than absorbed. Phytosterols also have the additional role of helping promote healthy bile salt excretion in the intestines.
The phytosterol blend in Complete Liver Cleanse can help minimize the absorption of cholesterol from high-protein food sources, help retain healthy cholesterol levels that are within normal limits, and move bile sat through the digestive system.
Fiber and detoxification
Fiber plays a key role in the removal and excretion of intestinal toxins in detoxification. Only fibers that can effectively bind toxins will be successful in eliminating these harmful substances. Due to the unique benefits of individual fibers, the best binding, removal, and elimination effects are noted when combining different fiber types. Complete Liver Cleanse contains a combination of oat beta-glucan and konjac fiber that has been shown in scientific studies to bind to bile salts.
Dietary fibers are complex mixtures of cellulose, hemicellulose, pectin, mucilage, and gums, which are resistant to digestive fluids or enzymes – that is, they aren’t absorbed into the bloodstream. So, while fiber itself doesn’t necessarily provide nutrients, it does promote laxation and modulate gastric and intestinal physiology. Intestinal flora that normally reside within the colon utilize fiber as a medium for microbial fermentation, resulting in the synthesis of the vitamins, vitamin K and biotin, and the formation of short chain fatty acids, or SCFA.
SCFA have a simple, but important job: to be absorbed by the colon mucosa, increasing fecal matter bulk and providing energy. Fiber has been demonstrated in numerous clinical studies to provide support of gastrointestinal, cardiovascular, immune, and endocrine function health.
Complete Liver Cleanse also features two unique fibers to promote detoxification – konjac and oat beta-glucan.
Konjac, (Amorphophallus Konjac) is a tuber native to
As a fiber, konjac has shown positive results maintaining healthy cholesterol levels within normal limits in clinical studies. This beneficial effect is due to konjac’s ability to boost excretion of bile acid.
Oat beta-glucan has been a widely studied fiber source for supporting healthy cholesterol levels within normal limits.
In a randomized clinical study, oat beta-glucan showed support of healthy HDL/LDL ratios already within normal limits in individuals over a three week trial.
Closely linked to cholesterol, oat beta-glucan has also been studied for its support of healthy bile excretion.
Fiber has benefits beyond maintaining healthy cholesterol levels already within normal limits. It also contributes to healthy blood sugar levels already within normal limits. In a double-blind, clinical study, the oat beta-glucan fiber used in Liver Cleanse was shown to have 4 times higher viscosity than another high concentrate beta-glucan fiber.
Viscosity – the resistance to flow – is an important factor in beta-glucan, and all fiber. Water, for instance, would have a low viscosity, because it provides very little resistance to movement. Fiber, on the other hand, should have a higher viscosity in order to maximize its transit time through the GI tract, providing a gentle “scrubbing” on the intestinal walls. Therefore, the higher the viscosity, the greater the potential benefit.
Three capsules in the morning and three capsules at bedtime for 14 days.
Warnings: Do not use if you know or suspect you have an obstructed bile duct or problematic gallstones. If pregnant, nursing or taking prescription drugs, consult your healthcare practitioner prior to use. Keep out of reach of children.
Soft Drinks Contaminated by Benzene
May 27, 2006 09:24 AM
A Food and Drug Administration (FDA) testing program has found cancer-causing benzene in soft drinks at levels averaging four times the standard for tap water. The brand names have not been released.
The test data were uncovered by the Environmental Working Group (EWG), which posted the test results on the group’s website, www.ewg.org
Highly elevated Benzene Levels
Between 1995-2001 the RDA tested 24 samples of diet soda for benzene. The result: 79% tested at levels above the federal limit for benzene in tap water, which is 5 parts per billion (ppb). The maximum benzene level detected was 55 ppb. In addition to the diet sodas, the FDA tested a number of other non-diet soft drinks. One cola was contaminated at 27 times the tap water limit, and fruit drink had a 95 ppb level.
“These results confirm our suspicions there are highly elevated benzene levels in some very popular drinks,” Richard Wiles, EWG’s senior vice president said in a press release.
Reaction Triggered by Preservatives
According to an article in beveragedaily.com, sodium benzoate and ascorbic acid in soft drinks can react together to form benzene. Sodium benzoate is a common preservative in soft drinks, and ascorbic acid is often added as an antioxidant to extend shelf life.
Negotiations between the FDA and the beverage industry in 1990 resulted in an agreement that the industry would voluntarily reformulate its soft drinks to prevent this combination. The recurrence of benzene contamination may be due to new soft drink manufacturers in the market who were not a part of, or aware of, the original negotiations.
Britain Pulls Soft Drinks from Shelves
In contrast to the U.S. situation, food safety campaigners in England were successful in having benzene –containing soft drinks removed from the supermarket shelves. The British Food Standards Agency pulled four soft drink brands which contained more than 1 ppb of benzene, and rushed out the results of tests on 149 drinks, including a range of fruit juice, iced tea, squash, fizzy and low-sugar drinks, according to The Times of London.
The Wellness Revolution and Contaminated Soft Drinks
The controversy over benzene in soft drinks is an example of how toxic exposure exists in our food and immediate environment. The constant exposure to toxics were-and especially our children—experience is a major cause of chronic illness.
In this situation, the organic products available for purchase in health food stores are especially vital. And since some exposure to toxics is unavoidable we must take advantage of the herbs and nutrients that support detoxification and the liver, the main organ of detoxification, as well as immunity for example, Silymarin, N-acetyl cysteine, calcium D-glucarate, folic acid, Reishi and shiitake mushrooms, and turmeric.
Sources: www.ewg.org www.beveragedaily.com 02/25/06. Associated Press 04/11/06. www.fda.org.
Public Pressure Forces Corporations to Curtail Most Soda Pop sales to schools
The Nation’s largest beverage distributors have agreed to halt nearly all soda sales to public schools, according to a deal announced may 3rd by the William J. Clinton Foundation.
The companies have agreed to sell only water, unsweetened juice and low fat milks to elementary and middle schools, according to a spokesman for former President Bill Clinton. Diet sodas would be sold only to high schools.
The deal follows a wave of criticism by school districts and state legislatures amid reports of rising childhood obesity. Soda has been a particular target because of its caloric content and popularity among children.
TMG Fact Sheet
December 07, 2005 02:13 PM
TMG Fact SheetNeil E. Levin, CCN, DANLA 03/07/05
LIKELY USERS: People with high homocysteine levels; People with risks of developing Alzheimer’s Disease; People needing greater metabolism of fats; People with liver detoxification challenges; People consuming alcohol KEY INGREDIENTS: TMG is composed of three methyl groups attached to a glycine atom. It can “donate” methyl groups.
MAIN PRODUCT FEATURES: TMG is a metabolite of the B vitamin family product called Choline. Choline has 4 methyl groups, TMG has 3 and DMG has 2. These substances plus Folic acid, Vitamin B-12 and SAM-e are all methyl donors. Methyl donors can contribute methyl groups to biological processes such as liver function, detoxification and cellular replication (production of new cells). Methylation protects the kidneys and stimulates production of the fat-transporting molecule l-carnitine.
TMG helps the liver metabolize fats, preventing the accumulation of fats in the liver. It also helps to detoxify chemicals in the liver, while protecting the liver from being damaged by those chemicals.
Methylation with TMG helps to convert the dangerous, inflammatory chemical homocysteine into the amino acid methionine. TMG may lower homocysteine when B-6, B-12 and folic acid cannot.
ADDITIONAL PRODUCT INFORMATION: TMG is also known as Betaine and is a component of Betaine hydrochloride (Betaine HCl), a stomach acid supplement that is very acidic. But Betaine HCl is not used in the same way as TMG. TMG is not highly acidic and will not supplement low stomach acid.
TMG may be useful for autistic children, along with B-6 and magnesium. It may also be useful in strengthening the body’s immune response against pathogenic bacteria. There is very preliminary evidence that TMG and methyl donors may help against some forms of seizures.
DMG has been used as a sports supplement. TMG is 50% more effective than DMG in any application where the methyl groups are useful. Otherwise, they can used interchangeably.
SERVING SIZE & HOW TO TAKE IT: One serving per day, or up to 6,000 mg., as needed.
COMPLEMENTARY PRODUCTS: SAM-e, Milk Thistle (Silymarin), Dr. Verghese’s Liver Detoxifier & Regenerator, Antioxidants, NAC, Homocysteine Regulators, D-Flame, Detox Support
CAUTIONS: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement.
People with Parkinson’s or taking L-dopa should not use methyl donors like TMG without a physician’s specific approval and supervision. There are no other known drug interactions with TMG.
This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. This is not an official publication by any company, nor has this information been screened or approved by the FDA or any private company.
Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. REFERENCES:
Craig SA. Betaine in human nutrition. Am J Clin Nutr. 2004 Sep;80(3):539-49. Review. PMID: 15321791
Barak AJ, Tuma DJ. Betaine, metabolic by-product or vital methylating agent? Life Sci 1983;32:771-4 [review].
Benson R, Crowell B, Hill B, et al. The effects of L-dopa on the activity of methionine adenosyltransferase: relevance to L-dopa therapy and tolerance. Neurochem Res 1993;18:325–30.
Chambers ST. Betaines: their significance for bacteria and the renal tract. Clin Sci 1995;88:25-7 [review].
Charlton CG, Crowell B Jr. Parkinson’s disease-like effects of S-adenosyl-L-methionine: effects of L-dopa. Pharmacol Biochem Behav 1992;43:423–31.
Charlton CG, Mack J. Substantia nigra degeneration and tyrosine hydroxylase depletion caused by excess S-adenosylmethionine in the rat brain. Support for an excess methylation hypothesis for parkinsonism. Mol Neurobiol 1994;9:149–61.
Cheng H, Gomes-Trolin C, Aquilonius SM, et al. Levels of L-methionine S-adenosyltransferase activity in erythrocytes and concentrations of S-adenosylmethionine and S-adenosylhomocysteine in whole blood of patients with Parkinson’s disease. Exp Neurol 1997;145:580–5.
Crowell BG Jr, Benson R, Shockley D, Charlton CG. S-adenosyl-L-methionine decreases motor activity in the rat: similarity to Parkinson’s disease-like symptoms. Behav Neural Biol 1993;59:186–93.
Selhub J. Homocysteine metabolism. Annu Rev Nutr 1999;19:217-46 [review].
Brosnan JT, Jacobs RL, Stead LM, Brosnan ME. Methylation demand: a key determinant of homocysteine metabolism. Acta Biochim Pol. 2004;51(2):405-13. Review. PMID: 15218538 Gahl WA, Bernardini I, Chen S, et al. The effect of oral betaine on vertebral body bone density in pyridoxine-non-responsive homocystinuria. J Inherit Metab Dis 1988;11:291-8.
Olthof MR, van Vliet T, Boelsma E, Verhoef P. Low dose betaine supplementation leads to immediate and long term lowering of plasma homocysteine in healthy men and women. J Nutr. 2003 Dec;133(12):4135-8. PMID: 14652361
Olthof MR, Verhoef P. Effects of betaine intake on plasma homocysteine concentrations and consequences for health. Curr Drug Metab. 2005 Feb;6(1):15-22. PMID: 15720203
Schwab U, Torronen A, Toppinen L, Alfthan G, Saarinen M, Aro A, Uusitupa M. Betaine supplementation decreases plasma homocysteine concentrations but does not affect body weight, body composition, or resting energy expenditure in human subjects. Am J Clin Nutr. 2002 Nov;76(5):961-7. PMID: 12399266
Selhub J. Homocysteine metabolism. Annu Rev Nutr 1999;19:217-46 [review].
van Guldener C, Janssen MJ, de Meer K, et al. Effect of folic acid and betaine on fasting and postmethionine-loading plasma homocysteine and methionine levels in chronic haemodialysis patients. J Intern Med 1999;245:175-83.
Wendel U, Bremer HJ. Betaine in the treatment of homocystinuria due to 5,10-methylenetetrahydrofolate reductase deficiency. Eur J Pediatr 1984;142:147-50.
Wilcken DE, Wilcken B, Dudman NP, Tyrrell PA. Homocystinuria—the effects of betaine in the treatment of patients not responsive to pyridoxine. N Engl J Med 1983;309:448-53.
Wilcken DE, Dudman NP, Tyrrell PA. Homocystinuria due to cystathionine beta-synthase deficiency--the effects of betaine treatment in pyridoxine-responsive patients. Metabolism. 1985 Dec;34(12):1115-21. PMID: 3934499
Babucke G, Sarre B. Clinical experience with betain citrate. Med Klin 1973;68:1109-13 [in German].
Barak AJ, Beckenhauer HC, Badakhsh S, Tuma DJ. The effect of betaine in reversing alcoholic steatosis. Alcohol Clin Exp Res 1997;21:1100-2.
Barak AJ, Beckenhauer HC, Matti J, Tuma DJ. Dietary betaine promotes generation of hepatic S-adenosylmethioine and protects the liver from ethanol-induced fatty infiltration. Alcohol Clin Exp Res 1993;17:552-5.
Barak AJ, Beckenhauer HC, Tuma DJ. Betaine, ethanol, and the liver: a review. Alcohol 1996;13:395-8 [review]. PMID: 8836329
Freed WJ. Prevention of strychnine-induced seizures and death by the N-methylated glycine derivatives betaine, dimethylglycine and sarcosine. Pharmacol Biochem Behav. 1985 Apr;22(4):641-3. PMID: 2581277
Junnila M, Barak AJ, Beckenhauer HC, Rahko T. Betaine reduces hepatic lipidosis induced by carbon tetrachloride in Sprague-Dawley rats. Vet Hum Toxicol 1998;40:263-6.
Ji C, Kaplowitz N. Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice. Gastroenterology. 2003 May;124(5):1488-99. PMID: 12730887
Kettunen H, Tiihonen K, Peuranen S, Saarinen MT, Remus JC. Dietary betaine accumulates in the liver and intestinal tissue and stabilizes the intestinal epithelial structure in healthy and coccidia-infected broiler chicks. Comp Biochem Physiol A Mol Integr Physiol. 2001 Nov;130(4):759-69. PMID: 11691612
Kim SK, Kim YC, Kim YC. Effects of singly administered betaine on hepatotoxicity of chloroform in mice. Food Chem Toxicol 1998;36:655-61.
McCarty MF. Co-administration of equimolar doses of betaine may alleviate the hepatotoxic risk associated with niacin therapy. Med Hypotheses. 2000 Sep;55(3):189-94. PMID: 10985907
Murakami T, Nagamura Y, Hirano K. The recovering effect of betaine on carbon tetrachloride-induced liver injury. J Nutr Sci Vitaminol 1998;44:249-55.
Poschl G, Stickel F, Wang XD, Seitz HK. Alcohol and cancer: genetic and nutritional aspects. Proc Nutr Soc. 2004 Feb;63(1):65-71. Review. PMID: 15070439
Semmler F. Treatment of liver diseases, especially of fatty liver with betaine citrate. Ther Ggw 1977;116:2113-24 [in German].
Zapadniuk VI, Panteleimonova TN. [Cholagogic effect of trimethylglycine in normal animals of different ages and in experimental atherosclerosis] Biull Eksp Biol Med. 1987 Jul;104(7):30-2. Russian. PMID: 3620644
Autism & Seizures:
Rimland B. Seizures, Vitamin B6, DMG, and Sudden Speech. Autism Research Review International. 1996;10(2):1.
Roach ES, Carlin L. N,N-dimethylglycine for epilepsy. N Engl J Med. 1982;307:1081-82.
Vitamin B6/DMG. Letters to the Editor, Autism Research Interview International. 1994;8(2):6.
Reap EA, Lawson JW. Stimulation of the immune response by dimethylglycine, a nontoxic metabolite. J Lab Clin Med. Apr1990;115(4):481-6.
Hoorn AJ. Dimethylglycine and chemically related amines tested for mutagenicity under potential nitrosation conditions. Mutat Res. 1989 Apr;222(4):343-50. PMID: 2468082
Dr. Verghese, M.D. Liver Detoxifier & Regenerator Fact Sheet
December 07, 2005 12:16 PM
Dr. Verghese, M.D. Liver Detoxifier & Regenerator Fact Sheet Neil E. Levin, CCN, DANLA 02/10/05
LIKELY USERS: People with exposure to toxins that stimulate liver activity; People with exposure to infections that may have damaged liver tissue
KEY INGREDIENT (S): Milk Thistle extract (Silymarin), Glutathione, NAC, Bupleurum extract, Grape Seed Extract, Dandelion Root extract, Artichoke Leaf, Schisandra and about a dozen additional herbs, along with synergistic ingredients
MAIN PRODUCT FEATURES: This formula was developed by a physician based on his clinical experience.
Artichoke leaf has antioxidant properties and restores healthy growth to liver cells.
Bupleurum may promote normal cell growth, immune function and is a staple of Chinese liver formulas. Dandelion Root may serve as a natural down-regulator of inflammatory chemicals in the body. NAC supports liver Glutathionestores (antioxidant, detoxifier, heavy metal chelator). Schisandra protects liver cells from toxins and may help to regenerate damaged cells. Milk thistle’s antioxidant Silymarin improves liver function tests and protects liver cells against oxidative damage. It also protects liver cells by blocking and removing toxins from the liver. Silymarin aids in regenerating injured liver cells and blocks fibrosis.
OTHER IMPORTANT ISSUES: Samuel Verghese, M.D. (AM), Ph.D., BCIA-EEG, DAAPM, holds a degree in Alternative Medicine and specializes in Nutritional, Ayurvedic and other Alternative Health Solutions. He is certified as a BCIA-EEG Associate Fellow.
AMOUNT TO USE: Three or more capsules a day, preferably with meals.
COMPLEMENTARY PRODUCTS: Antioxidants (supports liver detoxification), Alpha Lipoic Acid, EGCg Green Tea Extract, Astragalus, medicinal mushrooms (shiitake, reishi), SAM-e (may improve bile flow and promotes methylation to detoxify chemicals), TMG, lecithin, thymus glandular extract, Cordyceps.
AVOID: acetaminophen, alcohol, iron supplements (also red meat, fortified flour)
CAUTIONS: This formula should not be used by pregnant women, nursing mothers children or those with liver problems unless recommended under the supervision of a healthcare professional. Please notify your physician about your supplement use if you are using any drugs! Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
1. Salmi HA, Sarna S. Effect of Silymarin on chemical, functional and morphological alterations of the liver. A double-blind controlled study. Scand J Gastroenterol 1982;17:517–21.
The wellness Revolution - 90% Of Americans Carry Chemical Stew in their Bodies.
October 01, 2005 01:22 PM
The Wellness Revolution
90% of Americans Carry Chemical Stew in their Bodies
The third national report on human exposure to Environmental Chemicals, issued this summer, shows that most people in the U.S., and especially children, carry a dangerous mixture of chemicals in their bodies. Nevertheless, the Center for Disease Control (CDC), authors of the report, issued a press release focusing on progress made in a few areas—and most media looked no further than the optimistic press release.
The CDC sampled the blood and urine of thousands of subjects across the country for 148 environmental chemicals. This study found a significant decline since previous reports in exposure to secondhand smoke and in lead levels in children’s blood.
Despite the positive headlines, however, the study documented the presence in human bodies of dozens of pesticides and toxic compounds used in consumer products. Among the findings:
Body Burden and the wellness Revolution
This Study—the latest indication that all of us carry a “body burden” caused by widespread chemical use in our society—shows the need for a system that relies on organic agriculture and alternative pest controls. The constant exposure to toxics we experience today is a major cause of chronic illness, including cancer, birth defects or abnormal development, brain or nervous system damage, hormonal and reproductive imbalances, and impaired immunity, to name just a few.
Meanwhile, individuals should take advantage of the organic products available in health food stores, and the herbs and nutrients that support detoxification and the liver, the main organ of detoxification, as well as immunity—for example, Silymarin, N-acetyl cysteine, calcium d-glucarate, folic acid, Reishi and shiitake mushroom, and turmeric. A healthy lifestyle and appropriate supplementation can offer some protection from societal pollution.
Sources: Third National Report on Human Exposure to environmental Chemicals, 2005, available at www.cdc.gov. Los Angeles Times, 7/22/05. A Brief Companion to CDC’s 2005 National Exposure Report, Physicians for Social Responsibility, www.psr.org. Pesticide action network, www.panna.org.
Pesticide Report Shows Widespread Body Burden.
September 16, 2005 10:50 AM
Women and Children Especially Vulnerable
Most Americans carry toxic pesticides in their bodies, according to a recent report. Often, the so called “body Burden” of these chemicals is well above government-defined safety levels. Included are pesticides linked to cancer, birth defects, low birth weight, declining sperm counts, and infertility.
Chemical Trespass, by the Pesticide Action Network, analyzes data collected by the Center for Disease Control (CDC) from blood and urine analyses of 9,282 people. Among the findings:
Pesticides residues and metabolites were found in every subject. The average person had 13 pesticides in his or her body. The Average 6 to 11 year old was exposed to certain organophosphorus (OP) pesticides at four times the levels deemed acceptable by the environmental protection agency. Children are especially susceptible to dietary pesticides since they eat more food on a body weight basis than adults.
Organochlorine (OC) pesticides were found as significantly higher levels in women. This probably reflects women’s higher body fat content; OC pesticides are stored in fatty tissue.
Mexican-Americans showed the highest pesticides exposure, probably due to their disproportionate employment in agriculture. However, the statistics did not include occupational information.
Many pesticides used widely in the past, such as DDT and chlordane, are still found in our bodies, even in children born years after they were banned.
Cause for Alarm?
The CDC, which tested for 116 environmental chemicals, stressed that presence of these chemicals in the body does not necessarily indicate disease and called for more study of the dosages that should cause concern. The Pesticide Action Network sharply criticized this approach as a “Failure to protect public health.” Much evidence links long-term, low-level exposure to chronic illnesses, the group said, and the problem is more acute when one considers the additive effects of combining chemicals.
Pesticides and the wellness Revolution
This study shows the need for a system that relies on organic agriculture and alternative pest controls. Meanwhile, individuals should take advantage of the organic products available in health food stores, and the herbs and nutrients that support detoxification and immunity—for example, Silymarin, N-acetyl cysteine, Reishi and shiitake mushroom, turmeric, and much more.
Sources: Second National Report on Human Exposure to Environmental Chemicals, Center for Disease Control, available online at www.cdc.gov.exposurereport Chemical Trespass, Pesticide action network, available online at www.panna.org
Maintaining Healthy Veins
July 25, 2005 09:36 PM
More than 40 million Americans have varicose veins, a term in Latin meaning “twisted and wollen blood vessel.” Although the condition is rarely disabling, it is disfiguring, causing discomfort and embarrassment to those afflicted.
many cases, genetic predisposition and gender determine who will develop varicose veins. A full 75% of Americans with the condition ar e women. At risk some women who may experience the beginning of this condition during pregnancy as the enlarging womb presses on the veins in the abdomen, increasing the pressure in the veins of the legs.
Age is another factor as the skin becomes less elastic, lessening vein support. Some individuals are genetically edisposed to a malfunction of the one-way valves that may cause a back low of blood to pool in super ficial veins, stretching and swelling them.
some health care professionals believe that our Western diet, high in refined carbohydrates and fat and low in fiber, may cause straining during bowel movement leading to hemorrhoids (anal varicose veins) and increase pressure on the leg veins. Our Western diet also eads to obesity and cardiovascular conditions such as plaque deposits in the arteries, abnormal clotting and platelet aggregation, cardiac dysfunction or failure, all leading to a weakened venous system that could increase the chance of developing varicose veins and edema (swelling in the legs). Those who ar e predisposed to varicose veins and who stand for long periods of time, especially on hard floors, may develop them more quickly.
If you are at risk of developing this condition as you age, emphasizing a diet high in fiber, legumes and grains, fresh fruits and vegetables will improve your chances of maintaining good vein health. Other nutritional supplements that may be beneficial are horse chestnut seeds, Centella Asiatica, Milk Thistle, Butcher’s Broom and bioflavonoids.
Horse chestnut seeds have a long historical use in the treatment of varicose veins and hemorrhoids. One active ingredient that has been researched is a saponin mixture called Aescin. In a recent study, Aescin was as effective as compression stockings in reducing leg swelling in patients with chronic venous insufficiency.
Centella Asiatica is a common edible herb also known as Gotu Kola in India. When grown in Madagascar, it has a higher content of a compound called triterpenic fraction (TTFCA) than the same herb has when grown in other parts of the world. This compound has been used for many years in the treatment of venous hypertension. In a study conducted in 1989, 120mg dosage was safely used in patients with poor venous blood flow and it improved the condition after one or two months.
Often, inflammation is a component of varicose veins. Milk Thistle, another herb commonly used for the treatment of liver disorders, was also found to reduce inflammation and edema in a recent Spanish study.
A bushy ever green perennial found throughout much of the Western world is Butcher’s Broom. Its saponin glycosides ar e anti-inflammatory and helped contract blood vessels, especially veins thus making it an important component of any natural for mulation used to improve venous conditions.
Certain bioflavonoids, such as quer cetin and rutin, have also been shown to be useful in the natural tr eatment of varicose veins as a strengthener of capillary and vein walls.
There are other nutritional supplements including vitamins and minerals that may help maintain vein health as we age. They are listed in my new book “A Doctor’s Guide to Natural Medicine.” To improve vein health and to decrease your chance of developing varicose veins: do not stand for long periods of time especially on hard sur faces such as concrete. If you can’t avoid this, make sure your shoes are well cushioned. If you are sitting for long periods of time either working or traveling, take walking breaks. Stop crossing your legs and exercise regularly to incorporates rhythmical contraction of the leg muscles. Rest with your legs elevated when taking a break. W earing good support hose and avoiding tight knee-highs will promote good blood flow.
These things can be very important if you ar e genetically pr edisposed to varicose veins. Starting nutrients early may help diminish or delay venous problems.
Micromedex, Inc. Volume 96, 1974-1998. Diehmetal. Microcirculation Laboratory, Cardiovascular Clinic, Chieti, Italy.
Efficacy of Centellase in the Treatment of Venous Hypertension Evaluated by a Combined Micro circulatory Model. G. Belcaroetal. Current Therapeutic Research, Vol. 46, No. 6, Dec. 1989.
Effect of Silymarin on Different Acute Inflammation Models and on Leukocyte Migration. R. de la Puertaetal, J. Pharm. Parmacol. 1996, 48: 968-970 Merck Sciential Review, no. 10, 1995-04-30, pp. 2
HERBS FOR A HEALTHY LIVER
July 14, 2005 03:38 PM
HERBS FOR A HEALTHY LIVER
The liver is extremely important in ridding the body of toxins. It is the key channel of elimination. Good health is impossible without adequate liver function. It is one of the most important organs in the body and often is not considered when it comes to health. The liver cannot function if digestion is poor or the colon is congested. Everything the enters the liver must be detoxified.
Everything we breathe, eat and absorb through the skin is refined in the liver; it becomes overburdened when too much is required. The liver is required to detoxify at a much higher rate than ever before. The exposure to toxins has increased rapidly over the years. The liver works by using enzymes to break down toxic material. The liver then converts the material from a fat soluble form to a water soluble form to be eliminated through the kidneys.
Milk thistle has a complex of compounds known as Silymarin. These substances are actually known to protect the liver against some toxins and help increase the function of this important organ. Silybin found in this herb is used as an antidote to the deadly deathcap mushroom which is known to destroy liver cells. It also contains amines (thyramine and histamine) which are known to help stimulate the production and flow of bile. Milk thistle has been proven to be very beneficial on liver function.
Studies done recently indicate that milk thistle is beneficial for severe liver disorders such as hepatitis and cirrhosis, as well as general liver restoration, protection and strengthening. The properties of milk thistle have been confirmed in animal studies to be a protection in liver disorders.
Turmeric has been found to contain liver protective properties similar to the glycyrrhizin found in licorice. This ability may be due to its powerful antioxidant activity. It also has been found to increase enzymes in the liver to pre vent inflammation. Turmeric has also been found to increase bile acid output. Turmeric has the ability to breakdown carcinogens and toxins allowing them to be excreted from the body without doing damage. It seems to protect the liver from toxic damage.
Licorice contains glycyrrhizin and glycyrrhetinic acid which help stimulate interferon in the body which is essential for protecting the immune system. It also contains liver protective properties preventing damage due to toxic exposure. Glycyrrhizin found in licorice is thought to inhibit cell injury. Glycyrrhizin has been found in studies to be beneficial in treating cases of chronic hepatitis B. It seems to improve liver function as well as reduce liver enzymes that are known to determine liver damage.
Scientific studies have found that schizandra protects the liver against toxins. Problems with the liver and lead to immune disorders because of the build up of toxins. Schizandra has also been found to protect against the effects of alcohol in mice. Other studies have found this herb to have a mild regenerative effect on the liver . It is used in China to treat infectious hepatitis. It helps to protect the liver from damage and encourage liver regeneration after injury or illness.
July 12, 2005 10:28 AM
SUMMARY OF SPECIFIC ACTIONS ASSOCIATED WITH MILK THISTLE
July 12, 2005 10:27 AM
SUMMARY OF SPECIFIC ACTIONS ASSOCIATED WITH MILK THISTLE
ESTROGEN-RELATED DISEASES AND SILYMARIN
July 12, 2005 10:25 AM
ESTROGEN-RELATED DISEASES AND Silymarin
Like other bioflavonoids such as quercitin and proanthocyanidin, Silymarin helps to control the risk of estrogen - related diseases such as breast tumors. Research suggests that when the liver is functioning properly, bad forms of estrogen can be filtered from the body. If the liver is congested or damaged, these substances continue to circulate and may be responsible for the development of specific diseases such as breast cancer. Keeping the liver healthy is vital for women because they must deal with estrogen / progesterone peaks and valleys. Frequently, the role of the liver is helping the body deal with hormones is not stressed enough by standard medical practitioners.
THE CARDIOVASCULAR SYSTEM AND MILK THISTLE
July 12, 2005 10:23 AM
THE CARDIOVASCULAR SYSTEM AND MILK THISTLE
Silymarin may also be helpful to people suffering from high blood pressure and those that have experienced heart attacks. The flavonoids in Milk Thistle act as free radical scavengers, which are important in preventing damage to artery walls.
TREATING PSORIASIS WITH SILYMARIN
July 12, 2005 10:19 AM
TREATING PSORIASIS WITH Silymarin
There is some evidence to suggest that abnormal liver function may play a role in the development of psoriasis. Because the liver is responsible for filtering toxins out of the blood, its connection to disease like psoriasis may be very significant. Psoriasis has been linked to certain toxic substances which circulate throughout the bloodstream. If the liver is compromised and these toxins are not properly filtered, they can cause the psoriasis to become more pronounced. The presence of leukotrienes has also been connected to psoriasis. As mentioned earlier, Silymarin inhibits the production of these damaging molecules. Another added benefit of Milk Thistle for people who suffer form psoriasis is that it also helps to balance certain cellular chemicals in the skin which determine the rate in which skin cells are reproduced.21
SILYMARIN’S EFFECT ON GALLSTONES
July 12, 2005 10:16 AM
Silymarin’S EFFECT ON GALLSTONES
Because Silymarin helps to promote the flow of bile by increasing its solubility, it may be very beneficial in treating or preventing gallstones. Studies have shown that taking Milk Thistle has resulted in a pronounced reduction of cholesterol in the bile.20 Whenever the flow of bile is increased, the chances of developing a gallstone are decreased. Intere stingly, some very low fat or even non-fat diets designed to produce quick weight loss have been known to cause gallbladder attacks. When fats are drastically reduced, bile flow is inhibited resulting in stagnant bile, which is prone to forming stones. Keeping bile flow active is necessary for good health, digestion and the prevention of gallstones.
DO WE NEED EXTRA LIVER PROTECTION?
July 12, 2005 10:15 AM
DO WE NEED EXTRA LIVER PROTECTION?
Even if you don’t suffer from any liver disease or don’t abuse alcohol, you may still require the therapeutic effects of Milk Thistle. Everything that enters the liver through the portal vein must be de-toxified and neutralized. Many of us eat diets that are too high in protein, take overthe- counter or prescription drugs, and routinely expose ourselves to radiation and other pollutants. Everything we breath, eat and absorb through our skin is purified and refined in the liver. Some of the more detrimental compounds we ingest that increase the liver’ s work load include:
Dr. Andrew Weil, M.D. author of Natural Health, Natural Medicine says, “High protein diets impose a considerable work load on the digestive system and may contribute to feelings of fatigue and lack of energy.” The problem with protein is that the liver has to work harder to detoxify the body from the nitrogen waste which results when it is metabolized. This compound called ure a has to eventually be eliminated from the body through the kidneys.
Most of us are routinely exposed to nicotine, toxins of various kinds and a whole host of synthetic drugs fro m ibuprofen to steroids. Most of us overeat the wrong things and pass up what’s really good for us. High fat, high sugar, high protein diets stress the liver. Overeating, especially overcooked, fatty foods puts added strain on the liver. In addition, lack of exercise has an indirect effect on the liver. When we don’t exercise, an excess of toxins can build up and has to be transformed by the liver.
Typically, when we are exposed to chemicals which can injure the liver, the amount of glutathione in the liver d e c reases. When this substance is reduced, the liver becomes susceptible to damage. The Silymarin content of Milk Thistle keeps concentrations of glutathione in the liver elevated by up to 35%.19 The ability of the liver to detoxify the system is largely dependent on the present of glutathione.
According to the American Liver Foundation, liver diseases are the fourth leading cause of death up to the age of 65. It is not commonly known that a significant incidence of liver disease exists in this country. In the past, liver disease was only associated with chronic alcoholics. Now, however, liver disease strikes obese people, social drinkers and people who eat poorly. Milk Thistle can help prevent the subtle kind of liver damage any of us may be susceptible to.
SILYMARIN’S EFFECT ON A FATTY LIVER
July 12, 2005 10:08 AM
Silymarin’S EFFECT ON A FATTY LIVER
Frequently, when liver tissue sustains free radical damage, fatty acids are released. The presence of these fatty acids can cause inflammation and step up the production of damaging leukotrienes. This fatty infiltration of the liver can be caused by alcohol or other chemicals. Silymarin helps to neutralize this reaction by inhibiting lipid break down, which decreases the presence of fatty acids. Intere stingly, while fatty acid production is counteracted by Silymarin, protein synthesis is stimulated. This action causes an increase in the production of new liver cells, which is so vital if the liver is damaged or diseased. This stimulatory e ffect only applies to healthy cells and does not affect malignant ones.18
LEUKOTRIENES AND SILYMARIN
July 12, 2005 10:06 AM
LEUKOTRIENES AND Silymarin
The liver can also sustain damage from the presence of compounds called leukotrienes. These are produced when an oxygen molecule is transferred to a polyunsaturated fatty acid. In order for this reaction to occur, an enzyme called liooxygenase must be present. The Silymarin in Milk Thistle inhibits the action of this enzyme which results in a decrease in the formation of these leukotrienes.17
THE ANTIOXIDANT ACTION OF SILYMARIN AND ALCOHOL CONSUMPTION
July 12, 2005 10:05 AM
THE ANTIOXIDANT ACTION OF Silymarin AND ALCOHOL CONSUMPTION
Certain substances can damage the liver by producing or behaving like free radicals. These volatile molecules are highly reactive and their action can destroy living tissue. Alcohol is one of these substances. Because Silymarin acts as an excellent antioxidant, it should be taken by anyone who consumes alcohol or other toxic substances such as drugs etc. Studies have shown that milk Thistle can help to prevent liver damage caused by pharmacologic drugs.13
Studies have proven that Silymarin’s antioxidant activity is up to ten times more potent than vitamin E.14 Technically speaking, Silymarin helps prevent the depletion of glutathione (GASH), which can result from an excess of alcohol consumption or from other toxin exposure. It also increases the basal GASH of the liver by 35 percent.15 GASH plays a very vital role in detoxifying the liver. Concerning patients with chronic alcoholic liver disease, tests concluded that: “The scavenger, Silymarin is able to increase the antioxidant protection of the cells by ameliorating the deleterious effect of free radical reactions.” 16
Alcohol consumption, which in some individuals can be as little as one to two ounces can be enough to cause significant liver damage, which can lead to immune system suppression. For this reason, if you drink, even just occasionally, antioxidants such as Silymarin, selenium, Vitamin C and E should be taken regularly. Silymarin prevents liver damage by acting as a powerful antioxidant more potent than vitamin E or C. Milk Thistle should be added to the antioxidant array which is currently touted as effective free radical scavengers.
Unlike vitamin C, A or E, Milk Thistle remain relatively unknown as an effective antioxidant.
SILYMARIN: LITTLE KNOWN ANTIOXIDANT
July 12, 2005 10:02 AM
Silymarin: LITTLE KNOWN ANTIOXIDANT
The antioxidant bioactivity of the Silymarin compounds contained in Milk Thistle have been generally overlooked by experts who suggest taking vitamin E, C, A, beta - carotene and selenium supplements. Adding Milk Thistle to this complement of antioxidants is strongly recommended, especially for anyone who smokes, consumes alcohol or must take drugs on a continual basis. The hepato-protective properties of Silymarin combined with its free scavenging action make it an invaluable defense against so many toxins which pollute our bodies. Studies suggest that taking Milk Thistle on a daily basis may provide the liver with protection against heavy metals, environmental pollutants and dietary toxins. One study confirmed that Silymarin did indeed neutralize the damaging effects of cadmium, which can accumulate in living tissue.11
The implications of clinical trials on Milk Thistle suggest that regular ingestion of Silymarin can provide a significant amount of free radical protection during the course of one's inevitable encounter with air, water or food born pollutants.12
The protective potential of Milk Thistle has only just begun to be investigated. If it can perform so admirably against potent poisons, it most likely has a whole host of other protective actions. As an antioxidant, it should be added to the typical list of supplements we need to take for cellular defense.
MILK THISTLE: A VITAL COMPONENT OF LIVER REHABILITATION
July 12, 2005 10:01 AM
MILK THISTLE: A VITAL COMPONENT OF LIVER REHABILITATION
In addition to the flavonoid-like components of Silymarin, Milk Thistle seeds also contain betaine, which has proven itself as a liver protectant. Additionally, essential fatty acids are found in Milk Thistle which help control chronic inflammation.7
Milk Thistle should be a vital part of any therapeutic program designed to treat liver disorders. It can provide liver protection after exposure to radiation, heavy metals or toxic chemicals. Anyone who has hepatitis or cirrhosis should be using this herb as part of their treatment regimen. Concerning Milk Thistle and the liver, Christopher Hobbs wrote:
“I first learned of Milk Thistle in early 1984, when I began harvesting seeds from wild plants growing in California and taking the liquid extract I made from them. I had sustained heavy damage to my liver as a result of having hepatitis twice, in 1963 and in 1967, and I was able to greatly restore my digestive power with the help of this herb. Since then, I have witnessed other surprising recoveries from severe liver ailments with the use of this herb.”8
There is no question that the Silymarin compounds of Milk Thistle have significant therapeutic value for liver diseases of various kinds including: hepatitis, fatty infiltration of the liver, cirrhosis, and inflammation of the bile duct.9
The tyramine and histamine content of Milk Thistle works to stimulate the production and flow of bile, which also benefits the liver. A whole host of laboratory tests from biopsies to clinical data confirm that Silymarin is particularly effective in treating and preventing liver damage from alcohol abuse or chemical exposure. Extensive clinical trails have clearly shown that Milk Thistle can reverse the symptoms of many liver disorders.
In addition, Milk Thistle can exert a therapeutic effect on chronic hepatitis, cirrhosis, fatty infiltration of the liver, cholestasis of pregnancy, cholangitis and pericholangitis.10 While the liver has a great capacity for regeneration, when it is diseased or damaged by toxins like alcohol, it can cease to produce badly needed liver cells. Milk Thistle can stimulate this proliferation. The earlier it is taken, the quicker recovery will be.
CARBON TETRACHLORIDE TESTING AND SILYMARIN
July 12, 2005 09:59 AM
CARBON TETRACHLORIDE TESTING AND Silymarin
Carbon tetrachloride is used in laboratory tests to assess the ability of a substance to actually protect the liver from any potentially damaging compound. Increasing the dosages of carbon tetrachloride takes the liver through fatty infiltration, fibrosis and eventually cirrhosis. During these tests, administering Milk Thistle extract resulted in effective protection of liver tissue from the toxic effects of the chemical.
THE DEADLY DEATHCAP MUSHROOM, SILYMARIN, AND LIVER DAMAGE
July 12, 2005 09:58 AM
THE DEADLY DEATHCAP MUSHROOM AND Silymarin
The protective action of Silymarin in the liver has been confirmed through several experimental and clinical studies. Animals who have had their livers exposed to toxic chemicals such as carbon tetrachloride, amanita toxin (deadly mushroom) and galactosamine were protected from damage by Milk Thistle.3 Animals who had their livers partially removed experienced some organ regeneration when treated with Milk Thistle.
In the 1970’s, additional research on the ability of Milk Thistle to de-toxify liver cells of deadly mushro o m poisoning was conducted. The poison of this mushroom is extremely toxic and usually results in death within two to five hours. Amantine causes severe hemorrhagic liver dystrophy and inevitable death. Even when the studies were undertaken, scientists did not expect Milk Thistle to offer any significant protection against such a volatile and deadly toxin. The two peptides which comprise the poison are the most potent liver damaging substances currently known. Sixty patients who had severe amanita poisoning in Europe were treated with Milk Thistle. The results were impressive.
In experiments where Silymarin was given before the amanita toxin was ingested, it was 100 percent effective in preventing liver toxicity.4 If given within ten minutes, it still neutralized the poison. Even after 24 hours, it was found to prevent death and liver damage.5
Not only did Milk Thistle protect the liver fro m amantine damage, it also helped to prevent the loss of weight normally seen in animals that have ingested the poison. The impressive results of these tests resulted in stepped up production of Milk Thistle extract, which has made it much more available now.
THE ACTION OF SILYMARIN ON THE LIVER
July 12, 2005 09:56 AM
THE ACTION OF Silymarin ON THE LIVER
The liver is responsible for detoxifying the body. Anytime we ingest potentially harmful chemicals, which include drugs or alcohol, liver cells must filter out these compounds. Michael Moore, author of Medicinal Plants of the Desert and Canyon West says:
“When the liver is overworked, or unequal to the task our brain gives it, its blood vessels enlarge, the fluids move m o re slowly through it as it tries to increase its working area; it gets enlarged and congested.” He goes on to say that Milk Thistle improves the quality of blood proteins which help move toxins out of the blood.
The chemical components of Silymarin are referred to as true hepato-protective or “liver friendly.” The capability of Milk Thistle to protect the liver and enhance its function is due largely to its ability to inhibit certain factors, which result in liver damage. The most significant of these are leukotrienes or free radicals. What makes the Silymarin compounds in Milk Thistle even more impressive is that while they protect, they also stimulate liver protein synthesis.2 This explains why even an injured liver can regenerate tissue more rapidly when Silymarin is present.
Leukotrienes, which harm liver tissue, are compounds which are created when oxygen transfers to a polyunsaturated fatty acid. Silybum compounds can help to inhibit the formation of these molecules. The flavonoid-like compounds which comprise Silymarin have two specific actions on the liver:
1. Silymarin binds hepatocyte (liver cell) membranes which protects them from the potential damage of environmental toxins, (such as the death cap mushroom), foreign chemicals, endogenous poisons and free radicals.
2. Silymarin enters the liver cells and promotes their ability to produce certain enzymes which are vital to liver health. This action can speed the healing of liver cells from injury or disease. By enhancing the production of these enzymes, liver cell regeneration is also stimulated.
July 12, 2005 09:54 AM
The active ingredients in Milk Thistle consist of a complex of compounds which are referred to as Silymarin. These substances can actually protect the liver against certain toxins, while simultaneously boosting the function of the liver. Milk Thistle contains some of the most potent liverp rotecting substances known. For this reason, it is an invaluable herb for the treatment of hepatitis, cirrhosis, jaundice and fatty degeneration of the liver.
In addition, silybin, one of the compounds found in Milk Thistle, has been used as an antidote to the lethal deathcap mushroom whose toxin targets liver cells. Because of this action, in Germany, Milk Thistle has been used to block the action of amanita mushroom poisoning. In the case of mushroom poisoning, the herb is administered intravenously.
Studies have indicated that Milk Thistle has valuable therapeutic merit for severe liver disorders and acts as liver restorative as well.1 Not only does it promote new cell growth in the liver, it also prevents the formation of damaging leukotrienes.
Because the liver plays a vital role in maintaining a healthy immune system, Milk Thistle can contribute to increased disease resistance. This link may explain why it also has value for anyone suffering from psoriasis or chronic fatigue syndrome.
In addition, Milk Thistle can legitimately be called an antioxidant. It helps protect the cells from free radicals by scavenging them before they can cause cellular damage. Flavonoids have tremendous value as antioxidants and Milk Thistle is rich in them. The flavonoid-like compounds of this herb help to promote cell membrane integrity and to reduce its permeability.
Milk Thistle also acts to protect the kidneys, brain and other vital organs from toxin damage, treats allergic reactions, reduces inflammation and promotes healing. It also helps to emulsify fats and enhance bile flow, making it a good remedy for indigestion.
July 12, 2005 09:52 AM
HISTORY or Milk Thistle
Natural substances which afford us protection from toxins and potential carcinogens have recently come to the fore front of scientific attention. Compounds known as antioxidants, which can help minimize the damaging effects of chemical stru c t u res called free radicals, are extensively used today. One of these protectant substances is not as familiar to most people as vitamin C or beta-carotene. It is an herb called Milk Thistle and it has some extraordinary protective properties. Milk Thistle, also known as Silymarin has enjoyed a long history of use in European folk medicine. Centuries ago, Romans recognized the value of this herb for liver impairments. They routinely used the seeds and roots of the plant to restore and rejuvenate a diseased liver. Pliny the Elder, an ancient Roman, re c o rded how the juice of Milk Thistle, when mixed with honey was used for carrying off bile. Dioscorides extolled the virtues of Milk Thistle as an effective protectant against snake bites. The genus silybum is a member of the thistle tribe of the daisy family. Two species of the plant exist and both are native to southern Europe and Eurasia. Plants which grow in the Southern United States actually have more potent seeds than their European and Asian counterparts. Milk Thistle is a stout and sturdy looking plant, which can grow up to 12 feet tall. The flower heads can expand to six inches in diameter and are a vivid purple color. They usually bloom from June to August. Very sharp spines cover the heads. The leaves are comprised of hairless, milky bands, and when young, are quite tender. Historically, the seed of Milk Thistle was used as a cholagogue which stimulated the flow of bile. The seed was also used to treat jaundice, dyspepsia, lack of appetite and other stomach disorders. Homeopathic uses included:
peritonitis, coughs, varicose veins and uterine congestion. While tonics were sometimes made from the leaves of Milk Thistle, the most valuable part of the plant was contained in its seeds.
Milk Thistle is also known as Marian Thistle, Wild Artichoke, Variegated Thistle or St. Mary’s Thistle. Reference to Milk Thistle as “Vi rgin Mary” stems from its white milky veins. Legends explained that these veins were created when Mary’s milk fell on the thistle. Subsequently, a connection between the herb and lactation arose, which has no scientific basis for its claims. Milk Thistle is frequently confused with Blessed Thistle, which does act to stimulate the production of mother’s milk. Gerarde, a practicing herbalist in 1597, said that Milk Thistle was one of the best remedies for melancholy (liver related) diseases. In 1650, Culpeper wrote of its ability to remove obstructions in the liver and spleen. In 1755, Von Haller recorded that he used Milk Thistle for a variety of liver disorders. Subsequently, Milk Thistle became a staple agent for the treatment of any kind of liver aliment. European physicians included it in their written materia medica. Unfortunately, for an extended period during the 18th century, the herb was not stressed, however in 1848, Johannes Gottfried Rademacher rediscovered its medicinal merits. He recorded in great detail how Milk Thistle treated a number of liver ailments and spleen disorders. His research was later confirmed in medical literature. In the early 20th century, Milk Thistle was recommended for female problems, colon disorders, liver complaints and gallstones. Almost every significant European pharmaceutical establishment listed Milk Thistle as a valuable treatment. In recent decades, Milk Thistle has been primarily used as a liver tonic and digestive aid. Nursing women who wanted to stimulate the production of their milk used Milk thistle as a traditional tonic. As mentioned earlier, modern day medical science now refutes this particular action of Milk Thistle, however, its benefit to the liver has been confirmed.
German herbalists have routinely used Milk Thistle for treating jaundice, mushroom poisoning and other liver disorders. This therapeutic tradition contributed to modern German research into Milk Thistle, resulting in its use as a widely prescribed phytomedicine for liver disease. Silymarin or Thisilyn, as it is also known, is a relatively new nutrient in the United States. Since 1954, scientists have known the Milk Thistle contained flavonoids, however, it wasn’t until the 1960’s that they discovered the just how unique Silymarin is. Silymarin was considered an entirely new class of chemical compound, and its therapeutic properties continue to impress the scientific community.
July 12, 2005 09:48 AM
NOTE: Most health food stores stock this herb under the name of Milk Thistle, however, it may also be found as Thisilyn, Silymarin or Silybum
STORAGE: Keep in a dark container in a cool, dry environment.
RECOMMENDED USAGE: Because Silymarin is not very water soluble, decoctions are not as effective as extracts and powder forms of Milk Thistle. The advantages of bound Silymarin should be investigated. Obtaining the best results with Milk Thistle depends on taking higher dosages three times daily before meals. For bound Silymarin, dosages are less. In cases where poisoning or alcoholism is severe, dosages may be increased without toxicity, side effects or allergic reactions. Alcohol based extracts are not recommended. The best forms of Milk Thistle are guaranteed to contain 80% Silymarin.
NOTE: A new form of Silymarin has recently become available, which may be even more absorbable than other types. It is Silymarin that has been bound to phosphatidycholine. Apparently this binding makes Silymarin compounds more clinically effective in the body.
SAFETY: No contraindications are associated with this herb even in substantial dosages. Milk Thistle has been extensively used in Europe and numerous studies have shown very little if no toxicity. Taking Silymarin can p roduce looser stools, although the effect is not that common. At high dosages, it may be desireable to add a source of fiber to the diet to prevent loose stools or digestive tract irritation. Suggested fibers include: psyllium, oat bran or pectin. Long term use of Milk Thistle poses no problem because of its non-toxicity. The long-term safety and advisability of the use of Milk Thistle extracts in pregnant or nursing women has not been established.
MILK THISTLE (Silybum marianum)
July 12, 2005 09:45 AM
MILK THISTLE (Silybum marianum)
COMMON NAMES: Christ’s Crown, Holy Thistle, Venus Thistle, Heal Thistle, Wand of God’s Grace PLANT PARTS: ripe seeds, or extract from the shell
ACTIVE COMPOUNDS: Seed extract contains a complex of three flavanolignans which are collectively referred to as Silymarin. These flavonoid-like compounds are silibin, silychristin and silydianin.
PHARMACOLOGY: The flavonoids contained in Milk Thistle have a strong liver protective action and have been extensively used in Europe as pharmaceutical p reparations for liver disorders. These include: silibin, silydianin and silychristin, which all combine to create Silymarin. Clinical trials have shown that Silymarin can protect the liver by counteracting a number of toxic substances including alcohol, acetaminophen, carbon tetrachloride and the Amanita mushroom poison.
Apparently, Silymarin actually alters liver cell membranes which prevent toxins from passing through the cell. It inhibits the release or the synthesis of certain enzymes which are toxic to liver tissue. In addition, these compounds stimulate cellular growth and reproduction by boosting protein synthesis. Milk Thistle seeds are also high in betaine hydrochloride, which may contribute to the hepato-protective properties of the plant.
Silymarin has also exhibited significant antioxidant capabilities and can help reduce inflammation by inhibiting certain enzymes. The seeds of the plants appear to have the highest concentration of Silymarin.
VITAMIN AND MINERAL CONTENT: rich in bioflavonoids CHARACTER: hepato-tonic, alterative, demulcent and protective BODY SYSTEMS TARGETED: liver, gallbladder, pancreas and stomach.
NEW PRODUCT ANNOUNCEMENT
July 05, 2005 06:29 PM
The Most Comprehensive Antioxidant Formula Available!
Four tablets contain: Vitamin A (as beta-carotene 8,500 IU & palmitate 4,000 IU) 12,500 IU
gamma-Vitamin E Complex 500 mg
Quercetin 100 mg
LIFE FORCE MULTIPLE - Essential Nutrients to Support Your Low Carb Lifestyle..
June 29, 2005 10:39 AM
Taking care of your body is an especially important challenge in today’s stressful and hectic world. Choosing a low carb lifestyle is an increasingly popular way to seek better health. In fact, there are approximately 30 million U.S. adults counting their carbs right now. While effective for weight control and therefore having positive health effects, low carb approaches can also result in serious nutrient imbalances. Thus, adding the right multiple to your low carb approach is an enormously important next step for your good health. LIFE FORCE MULTIPLE, the top-ranked and award–winning multiple from Source Naturals, replenishes these nutrients and provides compounds that will help your body process the increased proteins and fats better while you are restricting carbs.
Low Carb Benefits
Restricting carbs can have many health benefits. And lowering your intake of refined simple carbs, such as sugar and white flour, can help you promote healthy blood sugar and insulin levels, which is critical for your good health. Insulin is used to move the glucose from carbs into your cells for energy. Ingesting too many refined carbs can greatly reduce your body’s ability to use insulin well, which can lead to short and long-term health concerns.
Replenish Nutrients with LIFE FORCE
LIFE FORCE contains optimal levels of many nutrients that might be deficient in low carb meals. Counting carbs can lead to restrictions of nutrient dense foods such as dairy products, grains, fruits and vegetables. LIFE FORCE contains many of the same protective antioxidants, vitamins and minerals as fruits and vegetables, including beta-carotene, vitamin C, vitamin E, flavinols, magnesium and selenium. It also contains high levels of the same vitamins found in grains, including all of the B vitamins, to support your body’s healthy energy metabolism. And it contains nutrients found in dairy products such as calcium, potassium, vitamin A and vitamin D.
Support Healthy Fat and Protein Consumption with Life Force
Low carb lifestyles mean higher consumption of proteins and fats. Unfortunately, there are artery, heart, colon and many other health concerns associated with meals that are high in fat and protein and low in fiber and produce. However, the nutrients in LIFE FORCE can help you better process eating this way. LIFE FORCE contains high levels of protective fat-soluble antioxidants such as alpha lipoic acid, ascorbyl palmitate (vitamin C ester) and vitamin E to protect your body from the free radicals generated by consuming more fats. It also contains many nutrients for liver health, such as Silymarin, CoQ10, N-Acetyl Cysteine and turmeric to help support the fat metabolism your liver is responsible for. LIFE FORCE also contains a high level of the B vitamin biotin, which aids in fat, protein and energy metabolism.
Restricting simple carbs can do much more than help you maintain a healthy weight; it can also be the foundation for maintaining good health throughout your long life. But you need to develop a thoughtful holistic strategy for success. When you integrate LIFE FORCE MULTIPLE into your wellness plan, then you can benefit from decades of clinical research about the nutrients your body needs to support optimal health and a low carb lifestyle, long before this information becomes part of mainstream health recommendations. Join this wellness revolution by adding LIFE FORCE to your strategies for health and allow yourself to start feeling energized today!
Life Force - The Energy Activator
June 29, 2005 10:35 AM
Don’t Be Confused About Multiples – Get the Top-Ranked Multiple That Scores 100%
We can help you decide how to pick the most advanced daily multiple for your wellness. Listen to the experts. Source Naturals LIFE FORCE MULTIPLE was honored as a leading formula in an independent scientific analysis of 500 multiples, ranking higher than any other national brand. Lyle MacWilliam, author of the Comparative Guide to Nutritional Supplements (ide.com) ranked multiples based on criteria developed from the published recommendations of the most renowned nutritional authorities: Phyllis Balch, C.N.C.; Michael Colgan, Ph.D.; Earl Mindell, Ph.D.; Michael Murray, N.D.; Richard Passwater, Ph.D.; Ray Strand, M.D.; and Julian Whitaker, M.D. Source Naturals’ success in this rigorous scientific analysis reflects our Bio-Aligned™ formulation method. LIFE FORCE goes deep to the underlying cause of health imbalances by supporting multiple body systems. And now, based on the latest scientific research, we have improved the formula by adding even more antioxidants and other cutting-edge ingredients. According to Lyle MacWilliam, “Source Naturals made a top ranked multiple even better!” And based on Lyle’s analysis of the new formula, LIFE FORCE is now the highest rated multiple of any evaluated in the current edition of this guide, scoring a 100% rating.
Bio-Align™ Yourself with Life Force
LIFE FORCE MULTIPLE was chosen as one of America’s most elite and comprehensive multiples, as reported in the Comparative Guide to Dietary Supplements by Lyle MacWilliam, 3rd ed. LIFE FORCE received this acknowledgement by nutrition experts because it is uniquely effective. This Bio-Aligned Formula™ goes beyond ordinary multiples that simply replace nutrients missing from the diet. LIFE FORCE provides key organ-specific nutrients to support your body’s energy generation, heart, brain, immune system, musculoskeletal system, skin, liver, eyes, and more. When all your body systems function in harmony, everything in life comes together. Your mood is positive, your mind is clear, you’ve got energy in your step—that’s your LIFE FORCE working for you.
Get Ahead with Activated Energy and a Healthy Metabolism
Your metabolism determines how much you weigh, how energetic you feel, and the effective functioning of all your systems. LIFE FORCE is a rarity – a unique multiple containing an incredible number of nutrients at the potency levels that truly support your healthy metabolic function. For example, it contains coenzyme Q10, which plays a crucial role in cellular energy production. CoQ10 is a vital intermediate in the electron transport chain, one of the body’s energy production cycles, which converts glucose, or blood sugar, into ATP (Adenosine Triphosphate), a high energy molecule that is the body’s “energy currency.” LIFE FORCE also supplies alpha-lipoic acid and the potent R-lipoic acid form of lipoic acid, which are both referred to as the universal antioxidants and important intermediaries in the Krebs cycle, another energy production cycle.
LIFE FORCE also contains tyrosine and iodine, both precursors to thyroid hormones. These hormones regulate key metabolic functions like heart rate, digestive function, weight management and energy levels. No discussion of metabolism would be complete without mentioning the B vitamins and their coenzymated forms, such as thiamin cocarboxylase, riboflavin mononucleotide, and the methylcobalamin form of vitamin B- 12. These critical vitamins and their immediately bioavailable coenzymated forms are formulated to play critical roles in thousands of enzyme reactions that promote carbohydrate metabolism, energy production, and the mental functions that invigorate and activate you as you move through your busy days. And now green tea extract with EGCG (Epigallocatechin Gallate) has been added to the formula for added metabolic support.
Protect Your Heart and Circulatory System
The amazing muscular organ that is your heart beats more than 100,000 times a day, 365 days a year, promoting vitality and alertness by constantly oxygenating our tissues. LIFE FORCE supports your cardiovascular system with antioxidant coenzyme Q10, which helps support heart muscle metabolism. LIFE FORCE also contains the minerals potassium and magnesium, electrolytes vital for healthy heartbeat and heart function, and the herb hawthorn, a rich source of antioxidant flavonoids, which has traditionally been used as a heart tonic. LIFE FORCE also supplies vitamins B-6, B-12 and folic acid to help maintain healthy homocysteine levels and vitamin K to support healthy circulation. Unlike common multiples, it supports cholesterol wellness, circulatory health and antioxidant cardiovascular protection, with both the typical d-alpha form of vitamin E but and the more potent and effective gamma-tocopherol and similarly structured tocotrienols.
Skin and Musculoskeletal Support
LIFE FORCE furnishes nutrients to build healthy bones, muscles and skin. We all know that calcium and magnesium are crucial for bone health, but many people don't know that there are a variety of nutritional cofactors that help build bone, such as vitamin D (which enhances calcium absorption and utilization), boron, manganese and copper. LIFE FORCE also supplies vitamin C and copper, necessary nutrients for collagen production (collagen is a key constituent of connective tissue in joints, skin and other areas), and the cutting-edge nutrient methylsulfonylmethane (MSM), an assimilable form of the mineral sulfur, used by the body to build and maintain connective tissues, including joint cartilage, hair, skin and nails. Additional nutraceuticals to support healthy skin include DMAE bitartrate, CoQ10, and alpha lipoic acid. LIFE FORCE also now includes rutin, quercetin, green tea extract and 65% more turmeric extract for your joint comfort.
Brain and Nerves Nutrition
The hectic pace and constant demands of life can keep our pulse racing, our nerves jangling and our temples throbbing. Our nervous systems are crying out, “Help!” LIFE FORCE provides that help. LIFE FORCE supplies the most highly bioavailable and bioactive forms of the amino acid tyrosine – the N-acetyl form and the acetyl-L form. Tyrosine is an important precursor to epinephrine and norepinephrine (collectively known as the catecholamines), which helps you respond to stress. It also contains high doses of vitamins C and B-6, required by the adrenal glands to produce the catecholamines. In addition, LIFE FORCE delivers the full spectrum of B vitamins, all important for healthy nervous system function. Now LIFE FORCE also contains a more bio-available form of tyrosine, acetyl-L-Tyrosine. And LIFE FORCE contains Neuroceutical® nutrients that support healthy brain function by furnishing DMAE and choline. Both are precursors to the important neurotransmitter acetylcholine and are important for memory focus and muscular movement. Choline is also a precursor to phosphatidylcholine, an important constituent of the cellular membranes that surround and protect our brain cells. In addition, LIFE FORCE contains the renowned herb Ginkgo biloba and now even more grape seed extract, both effective antioxidants that can prevent lipid peroxidation, which is critically important for the high amounts of fatty tissue in the brain. LIFE FORCE—good food for the brain.
LIFE FORCE MULTIPLE supports your immune system, so you can feel your best through the seasons. LIFE FORCE contains the immunosupportive nutrient vitamin A, which fosters cell-mediated immunity and protects the epithelial linings of the respiratory and digestive tracts. Two forms of vitamin A are supplied: preformed vitamin A and its precursor, the potent antioxidant betacarotene. Other immuno-supportive nutrients in LIFE FORCE include vitamin B-6, vitamin C and zinc, which is fundamental for proper functioning of our T-cells, the “seek and destroy” cells of our immune system. LIFE FORCE also now includes 40% more lipoic acid, including the highly bioavailable alpha and R-isomer forms. Lipoic acid along with the B vitamins and CoQ10 promote building the energy reserves needed when the immune system needs to kick into high gear.
Powerful Liver Support
Your liver is responsible for converting many nutrients into their metabolically active forms before your body can use them. After activation, these nutrients travel through the blood stream to target organs where they perform their metabolic functions. Not only does the liver activate nutrients, but it also plays a crucial role in a variety of other metabolic functions, from fat digestion and cholesterol production to blood sugar regulation to the processing and elimination of toxins, an important role in today’s increasingly polluted world. For all these reasons, nourishing the liver is crucial. And LIFE FORCE does just that. LIFE FORCE contains alpha-lipoic acid, turmeric, Silymarin and N-acetyl cysteine (NAC) – all potent antioxidants that support healthy liver function. NAC and alpha-lipoic acid both help produce glutathione, one of the liver’s primary detoxifying molecules. Silymarin, the active flavonoid complex of the herb milk thistle, as well as coenzyme Q10, have been shown in vitro to inhibit lipid peroxidation of cell membranes. Turmeric extract promotes bile flow and is a rich source of the antioxidant, curcumin. LIFE FORCE also contains choline and inositol, vitamin- like molecules which act as lipotropics, unique substances that prevent the deposition of fat in the liver. Since the liver is naturally high in fats, LIFE FORCE is one of the only multiples that contains the fat-soluble form of vitamin C, ascorbyl palmitate, for antioxidant protection.
Complete Antioxidant Defense
Oxidative stress is the primary cause of accelerated aging. This and other forms of free radical damage are constantly threatening your body. Whether it is from pollution, ultraviolet light, food additives, or from other sources, it is more critical than ever to protect your body with antioxidants. LIFE FORCE contains 24 of the most powerful antioxidants known to science, including eight new antioxidants based on the latest research. It contains antioxidants that are water soluble, such as quercetin and rutin, and ones that are fat soluble, such as alpha-lipoic acid and lycopene. There are antioxidants that are especially protective of specific body systems, such as lutein to protect the macula in your eye, lycopene to protect your prostate gland, and tocotrienols to protect your arteries.
Cutting-Edge Vision Nutrition
The structure and functions of your eyes are very complex. LIFE FORCE contains nutrients to help support and maintain healthy eye tissue, which is particularly susceptible to oxidative stress from free radicals. To support your healthy macula, aqueous tissue and optical nerve signals, LIFE FORCE includes ingredients such as lutein, astaxanthin, beta carotene, bilberry, zinc, lipoic acid and quercetin.
Life Force Replenishes Essential Nutrients to Support Your Low Carb Lifestyle
LIFE FORCE contains optimal levels of many nutrients that might be deficient in low carb meals. Counting carbs can lead to restrictions of nutrient-dense foods, such as dairy products, grains, fruits and vegetables. LIFE FORCE contains many of the same protective antioxidants, vitamins and minerals as fruits and vegetables, including betacarotene, vitamin C, vitamin E, flavinols, magnesium and selenium. It also contains high levels of the same vitamins found in grains, including all of the B vitamins, to support your body’s healthy energy metabolism. And it contains nutrients found in dairy products, such as calcium, potassium, vitamin A and vitamin D.
Support Healthy Fat and Protein Consumption with Life Force
Low carb lifestyles mean higher consumption of proteins and fats. Unfortunately, there are artery, heart, colon and many other health concerns associated with meals that are high in fat and protein and low in fiber and produce. However, the nutrients in LIFE FORCE can help you better process these foods when eating this way. LIFE FORCE contains high levels of protective fat-soluble antioxidants such as alpha lipoic acid, ascorbyl palmitate (vitamin C ester) and vitamin E to protect your body from the free radicals generated by consuming more fats. It also contains many nutrients for liver health, such as Silymarin, CoQ10, NAcetyl Cysteine and turmeric to help support the fat metabolism your liver is responsible for. LIFE FORCE also contains a high level of the B vitamin biotin, which aids in fat, protein and energy metabolism.
Complete Energizing Nutrition
LIFE FORCE is the only multiple to target organ systems with specific nutrients and bio-botanicals, antioxidants and Neuroceuticals® for total body harmony and energy activation, system by system. Only this dedication to going deep to the cellular root of system imbalances can produce a multiple so effective that it is acknowledged in a prestigious scientific review, the Comparative Guide to Nutritional Supplements. A nutritional program with LIFE FORCE at its center can be an easy first step in joining the Wellness Revolution. The goal of this revolution is a long, healthy and fulfilling life. Allow yourself to feel your best, to achieve mental and physical harmony, to radiate energy and vitality. Feel your LIFE FORCE!
RENEWAL ANTIOXIDANTS - The Most Comprehensive Antioxidant Formula Available
June 24, 2005 05:34 PM
The average American’s life expectancy has risen dramatically over the last 100 years. Ideally those extra years will be quality ones. High levels of stress and exposure to environmental and dietary toxins can deplete our antioxidant stores, leaving us more susceptible to chronic health challenges. When we are young and healthy the body unleashes its own antioxidants, but as we age this internal antioxidant producing system declines and the body needs help. Free radicals cause oxidative stress, which is a major cause of accelerated aging. Source Naturals presents the science of RENEWAL ANTIOXIDANTS. This Bio-Aligned Formula™ is a significant advancement over other products currently available. No other formula provides the broad range of high potency, established and newly discovered water and fat-soluble antioxidants that RENEWAL ANTIOXIDANTS delivers.
Bio-Aligned Antioxidant Support
RENEWAL ANTIOXIDANTS™ supports multiple body systems with a balanced spectrum of plantioxidants™ (botanical extracts with unparalleled ability to combat free radicals), vitamins and specialty nutrients that have powerful antioxidant properties. Research suggests dietary antioxidants help balance and modulate free radical activity and help maintain structure and function of important components of cells such as lipids, proteins, and DNA.
Oxygen is required by your cells to generate energy, but it also contributes to oxidative stress or free radical damage, which is one of the primary causes of age-related damage to cells and tissues. Free radicals are unpaired electrons that can damage cells and compromise the function of tissues and organs. Antioxidants make free radicals stable by providing them with an additional electron. Unfortunately, now the antioxidant is missing an electron so, ironically, it becomes a free radical, which requires another antioxidant to donate an electron. Because this process starts a cascade of free radicals, scientists strongly recommend a broad range of lipid and water soluble antioxidants to minimize this negative effect. No other antioxidant formula follows the science better than RENEWAL ANTIOXIDANTS to defend against the widest spectrum of destructive free radicals, including peroxyl, hydroxyl, and superoxide radicals, and singlet oxygen.
Antioxidants neutralize destructive free radicals and support cardiovascular health by halting the oxidation of cholesterol. Cholesterol is only harmful to us if it becomes oxidized. Oxidized cholesterol is an unstable molecule that damages arteries. RENEWAL ANTIOXIDANTS contains hearthealthy antioxidants including gamma E and tocotrienols, which are major lipid-soluble antioxidants that help maintain the integrity of cell membranes by preventing lipid oxidation. The formula includes hawthorn berry and grape seed, CoQ10, lycopene and other powerful antioxidants for heart support.
Nourishing the Brain
Antioxidants are critical for brain and nerve tissue because the brain is mostly composed of fats, which are very sensitive to free radical damage. Research has shown that stress can directly set in motion mechanisms that promote aging, which affects brain and nerve tissue. Ginkgo has been shown to increase memory performance and learning capacity as well as improve blood flow. It is also a free radical scavenger. RENEWAL ANTIOXIDANTS also contains DMAE, bilberry, CoQ10, grape seed, lipoic acid, vitamin B-2 and lutein for broad spectrum support.
Powerful antioxidants help minimize stress damage to liver cells and tissues, thereby supporting detoxification. N-acetyl cysteine is a powerful antioxidant. It is also a precursor to glutathione, a critical antioxidant and detoxifying substance produced in the liver. Silymarin is known for supporting the regeneration of the liver. Since the liver is prone to fat incursion, which makes it vulnerable to oxidative damage, the following fat soluble antioxidants provide critical protection: CoQ10, lipoic acid, ascorbyl palmitate, and gamma E.
The immune system is unlike other body systems in that it is not a group of physical structures but a system of complex interactions involving many different organs. White blood cells generate enormous amounts of destructive free radicals in order to kill invading organisms. Vitamin C, a free radical scavenger, is concentrated in these white blood cells at a much higher level than in surrounding fluid. This extends their life and effectiveness by providing them with a built in defense mechanism against their own free radicals. RENEWAL ANTIOXIDANTS provides water and fat-soluble vitamin C (ascorbyl palmitate and ascorbic acid) along with vitamin A, beta carotene, CoQ10, lipoic acid, quercetin, selenium, gamma vitamin E, tocotrienols, zinc and turmeric, for added immune defense.
Skin & Connective Tissue
Skin is rich in lipids, proteins, and DNA, which are extremely sensitive to oxidation. Age-related changes due to oxidation, loss of elastic fibers and thickening of collagen fibers, cause skin to become fragile and less supple. A broad array of antioxidants protects skin and helps maintain its structure and tone. These include beta carotene, vitamin C, vitamin E, grape seed, zinc, amla (Phylanthus emblica), quercetin, DMAE, manganese and myricetin. Amla is a very effective herbal tonic. It is rich in polyphenols and vitamin C.
Eye tissue is particularly prone to the effect of free radicals. Vision involves light being focused through the lens onto the retina. The macula, or center of the retina, receives the most light. However, sunlight is a powerful free radical generator. Lutein, a potent, fatsoluble antioxidant concentrated in the macula, helps maintain the integrity of the macula and the blood vessels that supply the macular region. The eye also has aqueous tissue that is better protected by water-soluble antioxidants, such as bilberry and grape seed. RENEWAL ANTIOXIDANTS provides these ingredients, along with lycopene, zeaxanthin, lipoic acid, vitamin A, beta carotene and ascorbyl palmitate to support healthy eyes.
Mitochondria, the tiny energy factories within the cells, are the major source of free radicals produced by our own bodies. These components of cells produce ATP (the energy molecule) and provide energy for all cellular activity; therefore, antioxidants are crucial to keep the levels of oxidants they produce in check. RENEWAL ANTIOXIDANTS provides the antioxidant power of green tea, lipoic acid, zinc, vitamin B-2, CoQ10 and Mega H-, a source of electron rich hydrogen ions. Coenzyme Q10 is fat-soluble and its primary functions include activity as an antioxidant and as a cofactor in many metabolic pathways, particularly in the production of ATP in oxidative respiration.
DNA, the blueprint for all molecules in the body, can be altered or damaged by oxidation. Protecting DNA is important for optimal health of all cells and tissues. According to invitro research, certain compounds, such as curcumin (from turmeric) and quercetin, can directly protect against strand-breakage and base oxidation. RENEWAL ANTIOXIDANTS contains these ingredients along with rosemary, pomegranate, raspberry, blueberry leaf, and carnosine. In in-vitro studies, L-carnosine reduced glycation, a process in which DNA and protein are damaged by glucose.
Living Longer, Living Better Strategies for Wellness
Taking personal responsibility for your health and exploring safe alternatives to support prevention is the basis for the wellness revolution. Your health food outlet is leading the way with education and quality products to help you take control of your well-being. Source Naturals is pleased to partner with these outlets to bring you the cutting edge nutritional science of RENEWAL ANTIOXIDANTS. Antioxidant protection is a fundamental part of the holistic healing system. Make this profound formula the cornerstone of your anti-aging program today.
Clement, M., Bourre, J. Graded dietary levels of RRR-y-tocopherol induce a marked increase in the concentrations of a- and y-tocopherol in nervous tissues, heart, liver, and muscle of vitamin E-deficient rats. Biochimica et Biophysica Acta 1334 (1991) 173-181. Borgstrom, L. Pharmacokinetics of N-acetylcysteine in Man. Eur J Clin Pharmacol (1986) 31:217-222. Hipkiss, A.R., et al. Carnosine, a protective, antiaging peptide? Int J Biochem & Cell Biol. 30, May 1998, 863-868.
Heart and Blood Vessels Resveratrol, Gamma E, Tocotrienols, Vit C, Hawthorn Berry, Grapeseed, Myricetin, CoQ10, Ginkgo, Beta & Alpha Carotene, Zeaxanthin, Lycopene, Lutein, Astazanthin, Lipoic acid, Green Tea, Bilberry, Ginger, Turmeric, Blueberry Leaf
Brain and Nervous System DMAE, Ginkgo, Carnosine, Bilberry, CoQ10, Grapeseed, Lipoic Acid, Vit B-2, Lutein
Liver Lipoic Acid, N-Acetyl Cysteine, Vit A, B-2,and C, Beta Carotene, Silymarin, CoQ10, Selenium, Zinc, Gamma E, Tocotrienols, Turmeric, Ginger Glutathione, Wheat Sprouts
Immune System Vit A & C, Beta Carotene, CoQ10, Lipoic Acid, Quercetin, Selenium, Gamma E, Tocotrienols, Zinc, Turmeric
Skin & Connective Tissue Beta Carotene, Vit B-2, C & E, Grapeseed, Lutein, Lycopene, Zeaxanthin, Zinc, Amla, Quercetin, Manganese, DMAE
Eyes and Vision Lutein, Beta Carotene, Vit A & C, Bilberry, Lycopene, Zeaxanthin, Lipoic Acid, Quercetin, Gamma E, N-Acetyl Cysteine, Selenium, Zinc
Energy Production and Metabolism Green Tea, Ginger, Mega H-, Ginkgo, CoQ10, Lipoic Acid, Zinc, Vit B-2, Carnosine DNA Protection Turmeric, Quercetin, Rosemary, Grapeseed , Resveratrol, Lycopene, Lutein, Tocotrienols, GliSODin®, Carnosine, Zinc, Manganese, Amla, Pomegranate, Raspberry leaf, Blueberry leaf
The important role the liver plays in maintaining health
June 21, 2005 04:56 PM
Most practitioners who practice various forms of natural medicine know the important role the liver plays in maintaining health in general. The liver is involved in thousands of biochemical mechanisms making it second only to the brain in importance and complexity. Natural health practitioners are also acutely aware of the detrimental effects on the liver of modern living, with its chemicals, excessive fat intake, pesticides, hormones, and stress. This suggests that we as a culture are in need of liver support. History suggests, and modern research is supporting, that botanicals have an important role to play in supporting a healthy liver.
The liver has an almost miraculous ability to biochemically transform, break down, store, eliminate, and build up the plethora of chemicals to which it is exposed. Many botanicals have a very specific effect of modifying these biochemical processes. Some botanicals can enhance the liver?s phase I (cytochrome P450) and phase II (glutathione conjugation) detoxification processes, promote the flow and production of bile (one means of eliminating toxins), inhibit the attachment of viruses or chemical antagonists to hepatocytes, strongly enhance the liver?s powerful antioxidant systems, or promote the regeneration of liver tissue-the liver being the only organ in the body except the skin able to regenerate itself. Many botanicals have been used historically for promoting liver health. Today, modern research is confirming these benefits while shedding light on their mechanisms of action. Following is an overview of a number of these botanicals.
Milk Thistle Silybum marianum
The extract of the seeds of milk thistle is perhaps the most well researched of all the liver supportive botanicals. Part of its benefit has been in its ability to scavenge free radicals and to stimulate the regeneration of hepatocytes. In Germany, it is the botanical extract of choice for use in supporting a healthy liver. Typically, an extract yielding a minimum of 70% Silymarin (a specific class of flavonoids) is used clinically at a dose of approximately 420 mg of the extract daily (Morazzoni and Bombardelli 1995).
Schizandra Schisandra chinensis
Schizandra, known as bei wu wei zi in China, is one of the most widely used tonics of Chinese herbalism. Its original use was to support the health of the heart, kidneys and lungs and as a longevity tonic. Modern research has focused attention on its role as an adaptogen and for supporting a healthy liver. Adaptogens are substances that positively affect overall health by reducing stress mechanisms which can contribute to a number of biochemical reactions that can be detrimental to health. While the mechanism of action of adaptogens has not been definitively determined, the existing literature suggests they work endocrinologically through the pituitary and adrenals and substantially reduce the negative effects that stress has on the system (Wagner et al. 1994). In China and Japan, the modern use of schizandra has focused on its benefit in those in need of liver support. In one review of its pharmacological activity, stabilization of liver enzymes was reported in more than 5,000 people. The benefits were experienced within 20 days of administration of schizandra with 75% of patients returning to normal values (Chang and But 1986). A limited number of controlled studies similarly reported on the beneficial effects of the equivalent of 1.5 grams of schizandra for reducing elevated liver enzymes (Liu 1991). There are three primary mechanisms of action of schizandra reported with regards to its ability to support a healthy liver: 1) its ability to reduce lipid peroxidation induced by a number of different antagonists (antioxidant activity); 2) induction of hepatomicrosomal cytochrome P-450; 3) stimulation of protein biosynthesis and liver glycogen (Liu 1991). Such mechanisms make schizandra ideal as a liver-supportive botanical that is underutilized in the West.
Bupleurum Bupleurum chinense, B. falcatum
Bupleurum, also known as chai hu in China, is perhaps the most important of liver-supportive botanicals in China and Japan, and, like schizandra, is far underutilized in the United States, except by traditional Chinese herbalists. Traditionally, it has been regarded as an herb that helps to normalize the function of the liver from a traditional Chinese perspective. Modern research has identified a group of compounds known as saikosaponins that strongly support liver health (in humans and rats). Mechanisms of action specifically regarding liver health identified for bupleurum include anti-inflammatory activity, as well as its ability to stimulate the production and release of bile, thus facilitating the detoxification process (Wagner et al. 1996).
Sho-Saiko-To Minor Bupleurum
In Chinese herbalism, herbs are seldom prescribed singularly. Rather they are combined according to very sophisticated principles of formulation based on the differential diagnosis of the patient. One of the most widely used and researched botanical formulas for the health of the liver used in China and Japan is Sho-Saiko-To, known in China as Xiao Chai Hu Tang (Minor Bupleurum). This classic formula consists of the following botanicals: ginger, scutellaria, jujube, ginseng, licorice, pinellia and bupleurum. It is widely used throughout Asia for supporting liver health and currently is the subject of phase II clinical trials at Sloan Kettering. The formula with its main ingredient, bupleurum, was first introduced in Japan by Chinese Buddhist priests between the 6th and 8th centuries. Modern research suggests that Sho-Saiko-To modulates the immune response, specifically in addition to other mechanisms, by increasing levels of interleukin and interferon (Huang et al. 2001).
To the same extent that herbs are seldom used singularly in Chinese herbalism, they are similarly used within a broader context that incorporates dietary and other lifestyle changes to support the botanicals. In my clinic, I routinely recommend that patients eliminate alcohol, coffee, sugar, and refined foods from their diet and eat whole grain foods, fish, and several servings of green vegetables daily along with their herbal program. For these individuals this is a simple program to follow, and many are able to live a normal productive life with a greater level of liver health. Such a liver-supportive program must be maintained as a way of life to lessen the burden that modern society and exogenous factors put on our livers.
The herbal world offers a potential natural health care approach that focuses on protecting and restoring the health and functioning of the liver. Both traditional experience and modern investigation suggest that botanicals can play a role in world health, specifically in promoting liver health.
The use of botanicals should be used under the guidance of a qualified health care professional. The combined use of conventional and natural therapies may not be appropriate. Before attempting to combine such therapies, discuss your therapeutic options with your primary health care provider.
Chang HM, But PH. 1986. Pharmacology and applications of Chinese materia medica. World Science. Singapore. Huang et al. Semi-quantitative analysis of cytokine mRNA expression induced by the herbal medicine sho-saiko-to (TJ-9) using a gel doc system. J Clin Lab Anal 15: 199-209. Liu GT. 1991. Pharmacological actions and clinical uses of Fructus schizandrae in recent advances in Chinese herbal drugs-actions and uses. Scientific Press Beijing. Morazzoni P, Bombardelli E. 1995. Silybum marianum (Carduus marianus). Fitoterapia LXVI (1):3-42. Wagner H, Noerr N. Winterhoff K. 1994. Plant adaptogens. Phytomedicine 1: 63-76. Wagner H, Bauer R, Peigen X, Jianming C, Offermann F. 1996. Chinese Drug monographs and analysis: Radix Bupleuri (chaihu). Verlag fuer Ganzheitliche Medizin Koetzting/Bayer. Wald, Germany.
Michael Tierra, L. Ac., O.M.D., is a clinician and world-renowned author of the best-selling Way of Herbs and Planetary Herbology. As product formulator for Planetary Formulas, he draws on 30 years of clinical experience to create formulas renowned for their dependability and effectiveness.
Are Standardized Herbs Better?
June 17, 2005 12:34 PM
Are Standardized Herbs Better?
Standardized is a term to mean that there is a guaranteed amount of a certain botanical constituent. For example St. John's Wort can be standardized to contain hypercin, Gingko can be standardized to contain flavones, Mahuang for ephedrine, and Milk Thistle for its Silymarin content. Standardized does not necessarily mean stronger or better. Chemical solvents such as hexane benzene, acetone, and methyl chloride are typically used in standardized extracts. Residues of the chemicals are found in the finished product. Furthermore they may be hazardous to the environment.
The problem with obtaining an amount of a standard constituent is, a plant can contain hundreds of active constituents. By concentrating on one component, we may lose synergistic compounds, which may improve effectiveness and lessen adverse reactions. Often scientists do not fully understand which constituents are beneficial for the clinical results of an herb. For example scientists are unclear whether or not hypercerin, hyperiform, or the interaction of several constituents, that have antidepressant properties in St. John's Wort. Once it was thought that the immune effects of Echinacea were due to echinosides; now it is thought that polysaccharides and proteins may also be immune supporting. In the case of ginseng, ginsenosides are found in ginseng leaves and roots, however ginseng leaves do not have same properties as the roots. In the South Pacific, locals all use Kava Kava roots, however German pharmaceutical companies use the stems to make standardized Kava Kava. Another drawback of standardized herbs is the chemicals used to manufacture them.
Advocates of standardized herbs are usually academics with little clinical experience with herbs, or researchers whose work is funded by companies that manufacture standardized products. Traditional herbalists seldom used standardized products for a variety of reasons. One, standardized extracts tend to be more expensive. Two, there is little evidence that they are more effective than the whole herb. For example, I have never seen studies comparing Gingko tea to standardized Gingko extracts; Ginseng standardized extracts have not been shown superior to whole ginseng root. Finally, many herbalists reject the pharmaceutical model of healthcare, which involves costly production techniques and capital investment to make a standardized extract.
Standardized herbs play a role in the drug model of herbal medicine, however traditional herbalists will continue to recommend herbs in more natural state which may include water and alcohol extracts, teas and pills that have not been standardized. (Factors that influence products quality include weather, soil, the time of year the plant is harvested, the age of the plant, the part of the plant being used, and the DNA of the plant, storage and processing.) You can also blend various batches of herbs to achieve a consistent potency; this is commonly done in the wine making industry. Finally you can add an active compound (synthesized) to an herbal product and the DNA of the plant, storage and processing.) The purpose of this article is not to condemn standardized herbs. It may be a good idea to remember that this form of herbal preparation is just one of many forms.
Cleanse That Body!
June 14, 2005 11:59 AM
Cleanse That Body! by Lisa James Energy Times, January 6, 2005
When toxins accumulate in your tissues, you can become fuzzy and sluggish. Here's how a New Year's internal cleansing can make you feel fresh and energized.
What's your New Year's resolution? Losing weight? Getting fit? Kicking the [fill-in-the-blank] habit? Whatever the shape of your dreams for 2005, it won't be easy launching a self-improvement program unless you give your body a fresh start. Where to begin? Detoxification-an internal cleansing that can supply the energy you need to succeed in achieving your goals.
No one can avoid toxins in our contaminated world, so many of us suffer from toxic overload, which can lead to fatigue, digestive problems and reduced immune function. " When we get out of balance, we get congested and toxic," says Elson Haas, MD, founder of the Preventive Medical Center of Marin in San Rafael, California (www.elsonhaas.com), and author of The New Detox Diet (Celestial Arts), "and our bodies' regular elimination systems cannot keep up with it. We have problems with our skin, our intestines, our sinuses. We also become deficient in vitamins, minerals and essential fatty acids. Most people have both congestion and deficiency, and they would benefit greatly from detoxification."
Toxins Within, Toxins Without
Life's fundamental activities-breathing, eating, walking around-generate waste in the form of free radicals, the unstable molecules that can ravage cells and tissues. What's more, Dr. Haas says that just "being under stress, being afraid, being anxious all produce more free radicals in the body" (like when a work deadline hits on the same day your car dies). When you add to your internal toxins all the noxious items coming from the outside, including the dietary ones, the recipe is very unhealthy.
" People are making poor choices in what they're putting in their mouths," says Dr. Haas. "They're taking in too much refined flour and sugar. There's a common problem in our country I call 'obese malnutrition'-people eating too many calories and not getting enough nutrition. People do a lot of junky fats and have a deficiency in the essential fatty acids that help protect cells."
Our bodies are also awash in manmade poisons such as food preservatives and additives, and residues from pesticides and herbicides. "The amount of toxic chemicals we are exposed to in our environment is staggering," says Susan Lark, MD, clinical nutrition expert and author of The Chemistry of Success (Bay Books). She notes that the average American is exposed to 14 pounds of such assorted chemical junk each year.
The body, however, does do its own housekeeping-and all of our cells detoxify every second of every day. "It's always a balance of garbage in, garbage out," says Dr. Haas, who has 30 years of experience in helping people detoxify. "Some of the toxins we break down into smaller components, some we just dump into the intestines for elimination."
Problems arise when there's more dirt than the internal maid service can sweep away. Dr. Lark notes that toxins wind up being stored in cells, especially fat cells, where they can hang out for years. When they are finally released "during times of low food intake, exercise or stress" complaints can range from tiredness to dizziness (sound familiar?).
That's where detoxification comes in, says Dr. Haas: "I think detoxification is a vital health care tool, particularly in this day and age when people are exposed to too many chemicals."
The process of detoxification starts with cleansing the intestinal system. Alternative health practitioners observe that discombobulated bowels can become overly permeable (a condition called leaky gut syndrome) and allow in all sorts of things that they shouldn't, such as semi-digested food particles, leading to inflammation and complaints that include rashes and joint pain.
Cleansing can be as simple as cutting down on what Dr. Haas calls the SNACCs-Sugar, Nicotine, Alcohol, Caffeine and Chemicals-or as thorough as a complete diet-and-supplement program with colonic irrigation (a sort of super-enema, professionally administered; if you're interested, contact the International Association of Colon Hydrotherapy at 210-366-2888 or www.i-act.org). The more powerful the program, though, the more likely you are to experience toxicity reactions such as nausea and headaches because of the volume of material being released. As Dr. Haas puts it:
" If you did water and green salads for a week, you'd detoxify more intensely than if you just gave up sugar and white flour." If you're feeling extremely rundown, take a gentle approach at first or consult a nutritionally aware practitioner, especially if you have a preexisting medical condition.
Getting more fiber is essential. Laurel Vukovic, a natural health teacher and author of 14-Day Herbal Cleansing (Prentice Hall), suggests following this daily regimen for two weeks: a teaspoon of psyllium (a fiber supplement); at least seven daily servings of fruits and vegetables, especially fiber-rich ones like apples, cabbage and carrots; and six glasses of water, along with daily exercise. Extra fiber "supports the intestines in eliminating the larger amounts of toxins that are released," says Vukovic, "prevent[ing] their reabsorption into the bloodstream." Some people find premixed cleansing formulas convenient; check your health food store shelves.
Fasting is a more intense detox approach that, according to Dr. Haas, "promotes relaxation and energization of the body, mind and emotions, and supports a greater spiritual awareness." He especially recommends fasting in the spring and autumn, which are times of transition. Some people do water-only fasts, but fresh vegetable juices are probably a better option, particularly if you haven't fasted before. Juices and plenty of fresh water also help cleanse the kidneys, another vital detox route.
Instead of juices you can use a special cleansing formula, such as the Spring Master Cleanser: 2 tablespoons freshly squeezed lemon juice, 1 tablespoon pure maple syrup and 1/10 teaspoon cayenne pepper in 8 ounces of spring water. Dr. Haas recommends drinking eight to 12 glasses daily (and rinsing your mouth after each glass to protect your teeth from lemon's acids), augmented by water, laxative herb tea, and peppermint or chamomile tea.
Try fasting for a day to see how you feel. Dr. Haas suggests starting out by fasting from early evening through the night, and eating a light breakfast the following day. Subsequent fasts can gradually increase in length-experienced fasters may go up to two weeks without food.
Break your fast properly; for juice or cleansing formula fasts, eat a raw or cooked low-starch vegetable, such as spinach or other greens. "Go slowly, chew well and do not overeat or mix too many foods at any meal," says Dr. Haas.
Don't forget your liver, the organ that transforms noxious chemicals into substances your body can eliminate. The herb milk thistle, used since ancient times as a liver tonic, contains Silymarin, which protects the liver from pollutants and helps it renew itself after toxic damage. Dandelion not only promotes the flow of bile from the liver, which helps clean out the junk, but also acts as a diuretic, helping the kidneys do their job. Green-food supplements, such as spirulina and cereal grasses, help neutralize toxins.
To maintain your cleansing gains, eat a healthy diet after detoxing. Focus on fresh organic foods, especially produce, beans and peas, whole grains and seeds (add organic poultry if you eat meat). Organic yogurt provides healthful probiotics, while fresh fish and ground flaxseeds provide omega-3 fats.
Clean Living Pays
The body's largest organ-the skin-provides a valuable contaminant exit path. Sitting in a hot tub or sauna "benefits the internal organs of detoxification," according to Dr. Lark, "by lessening the amount of toxins they must process." When sweatin' out the bad stuff, drink plenty of water and replace the calcium, magnesium and potassium lost through perspiration.
Another way to stimulate skin circulation is dry brushing, which also removes dead skin cells for a healthy glow (and is easier to fit into a daily routine). Using "a moderately soft, natural vegetable-fiber bristle brush" (Dr. Lark's suggestion), work in from the hands and up from the feet with light, short strokes that always move towards the heart. Vukovic says that a hot towel scrub is another option; put three drops of lavender essential oil in a basin of very hot water, dip in a rough terry washcloth and wring out, and then rub the skin briskly, starting with your feet and working your way up.
Once you've detoxified your body, you can start in on your immediate surroundings. Dr. Haas warns against using plastic food storage containers: "When food is heated in plastics some of the plastic material ends up in the food, especially if the food contains acids." Use glass containers instead. He also recommends avoiding aluminum pots and pans, and using stainless steel as an alternative.
Dr. Haas has seen what a good detox program can do: "It's amazing the kind of results people get-looking and feeling younger, more vital and healthy. They say, 'I'm sleeping like a baby,' they have fewer aches and pains. They have more peace in their bodies. I think detoxification is one of the keys to preventive medicine." So cleanse that body and let detoxification bring balance and renewal to your life.
June 10, 2005 04:08 PM
Basic Detox by Harriet Epstein , February 4, 2002
Basic Detox By Harriet Epstein Trying to stay healthy and clean in a dirty world can prove a difficult task. The rise of modern industry and agriculture has meant the widespread accumulation of toxins in our environment that can cause health problems.
As Kenneth Bock, MD, and Nellie Sabin point out in their book The Road to Immunity (Pocket), "Fat soluble chemicals are readily absorbed by the body but are difficult to excrete. To be excreted, they must first be enzymatically converted into water-soluble substances. Some of them can't be converted at all."
Bock and Sabin point out that a 1990 survey by the United States Environmental Protection Agency (EPA) that looked at people's tissues found that everyone the agency examined had styrene (a chemical used to make plastic) and xylene (a paint and gasoline solvent) stored in their bodyfat.
The toxins that you encounter every day are not only present in air and water, but also may be found in food and medicines. If we eat beef that's been exposed to pesticides, those chemicals may be shunted into our bodyfat. Pesticide residues in fruits and vegetables may end up in a similar place.
To cope with chemicals, the human body has evolved methods for detoxifying. When we breathe out we often release inhaled toxins. Other toxins are purged through urine, feces and sweat.
One of the chief organs responsible for cleansing the body is the liver. This organ utilizes a pair of chemical pathways for breaking down and eliminating toxins. In our hectic, industrialized world, this flow of toxins can overwhelm the liver's ability to detoxify. In addition, the dual processes the liver uses to eliminate noxious substances may become unbalanced, allowing toxins produced by one pathway to build up to dangerous proportions.
Once liver function falters, toxic havoc ensues. Toxins may remain in the body, often stored indefinitely in bodyfat. The body's detoxifying systems may be swamped with toxins.
In protecting the liver and enhancing its detox functions, many naturopathic practitioners recommend the herb milk thistle (silybum marianum). According to Steven Bratman, MD, and David Kroll, PhD, authors of the Natural Health Bible (Prima), milk thistle helps the liver cope with its toxic load. Consequently, milk thistle is frequently used in Europe for liver problems like jaundice.
Bratman and Kroll point out that milk thistle "is one of the few herbs that have no real equivalent in the world of conventional medicine." As Lise Alschuler, ND, medical director at the Bastyr Natural Health Clinic, told Natural Digest, "Milk thistle protects the liver against toxic damage (and) helps prevent damage to the rest of the body."
The compounds in milk thistle that help zap toxins, known as Silymarin, protect the liver by binding with substances that would otherwise interact with the liver and slow its function. They also help the liver repair itself and regenerate new liver cells.
As an extra bonus, Silymarin acts as an antioxidant, protecting liver cell membranes from oxidative damage.
Dandelion has a place as another traditional treatment for toning the liver and boosting the body's filtration system. The leaves are a cornucopia of antioxidants and nutrients including B vitamins, vitamins A, C and D, plus boron, silicon, potassium, magnesium and zinc. They help detoxify by acting as a mild diuretic: they cause the body to eliminate excess fluid.
But herbalists worldwide have found the compounds in dandelion root most useful for helping alleviate liver and gall bladder malfunction. (If you think you suffer these difficulties, consult your health practitioner.) Two unique and helpful natural substances found in dandelion root are chemicals called germacranolide and eudesmanolide. The root, according to the Natural Health Bible, has traditionally been used to speed up a sluggish or congested liver as well as detoxing the body by eliminating constipation. Research indicates dandelion root may stimulate bile flow (Arzneimittel -forschung 9, 1959: 376-378).
Juniper berries (Juniperus communis), may also be taken with dandelion as a diuretic. This botanical, often used to combat urinary tract problems, is also an anti-inflammatory (Phyto Res 1, 1997: 28-31).
Heavy metals rank as dangerous toxins unleashed by modern industry. As Michael Murray, ND, and Joseph Pizzorno, ND, explain in the Encyclopedia of Natural Medicine (Prima), metals like lead, mercury, cadmium, arsenic, nickel and aluminum can "accumulate within the (body) where they can severely disrupt normal function."
Public health experts estimate at least one in five Americans has been a victim of heavy metal poisoning. Lead may be the most common villain. In your everyday life, you may be ingesting metals from your cookware, from pesticides, cigarette smoke, dental fillings, polluted fish, and chipping house paint.
Signs that you may suffer from toxicity linked to heavy metals: Unusual fatigue, Persistent headaches, Unexplained muscle pains, Anemia, Ringing in the ears or dizziness and Tremors.
Of course, if you think you suffer from heavy metal poisoning, you should see a knowledgeable health practitioner as soon as possible. Murray and Pizzorno recommend an array of precautions to protect yourself against heavy metals in the environment:
Take a daily multivitamin and mineral.
Take extra amounts of vitamin C and B-complex.
Take amino acids that contain sulfur (taurine, cysteine and methionine) and high sulfur foods like onions and garlic (or supplements). (Consult your pharmacist of health practitioner before taking individual amino acids.)
In addition, Leo Galland, MD, in his book The Four Pillars of Healing (Random House) offers these tips for keeping your digestive tract functioning at top capacity:
Take supplements of lactobacil-lus acidophilus and lactobacillus plantarum, friendly bacteria that in-habit the large intestine. These microorganisms can help break down toxins and eliminate them.
Use aspirin and ibuprofen as little as possible. They increase the permeability of the digestive system, allowing allergens and other problematic substances to enter the body.
Do not use antacids. The stomach's acidic environment is designed to kill ingested bacteria and parasites.
To fight digestive problems or heartburn, cut back on saturated fat; eat smaller meals. Chewing on calcium tablets after meals may help. Foods that can exacerbate heartburn include coffee, alcoholic beverages and very spicy foods.
Dr. Galland also recommends not eating for four hours before bed.
Environmental Free Radicals
Detoxing the body may also require taking antioxidant nutrients to fight off what are called free radicals.
Free radicals are caustic molecues thought to be involved in causing many chronic problems such as cancer and heart disease. Free radicals are created within the body and its cells every time a metabolic activity takes place. While the human body has developed its own mechanisms for defending itself against these byproducts of metabolism, exposure to pollution, radiation and other toxins may overburden the body's free radical burden. Scientists believe that taking extra antioxidant nutrients like vitamins C and E and carotenoids (natural substances found in many vegetarian foods) may help prevent damage by free radicals.
Environmental oxidizing agents include ionizing radiation (from industry, sun, cosmic rays, x-rays) ozone and nitrous oxide (from auto exhaust) heavy metals (mercury, cadmium, lead) and cigarette smoke, along with other chemical and compounds from food, water and air. Free radicals are believed to play a role in more than sixty different health conditions, including the aging process, cancer and arteriosclerosis. (Proc Natl Acad Sci USA 1993;90:7915-7922).
The good news? Reducing exposure to free radicals and increasing intake of antioxidant nutrients can shrink the risk of these health problems.
"Antioxidants can't get rid of heavy metals and solvents," says Dr. Glidden, "but they do cut down on the damage they do while they're there. As toxins wander through your body, they generate metabolic reactions, resulting in free radicals. And anti-oxidants mop them up." The liver is the last line of defense in handling toxins; supplements help it regenerate itself.
The body itself does produce enzymes like Superoxide dismutase (SOD) catalase, and glutathione peroxidase which can defend against and defuse many types of free radicals.
Supplements of these compounds are also available to augment the body's supply.
These building block nutrients include the minerals manganese, zinc, and copper for SOD and selenium for glutathione peroxidase. Many vitamins and minerals act as antioxidants. Dr. Crinnion recommends a multivitamin with "a lot of B, especially magnesium."
Since chlorinated pesticides like DDT "rob the body" of B1 and Vitamin A, he says, it's a good idea to supplement these as well.
In addition, acidophilus, a beneficial bacteria that grows in the digestive tract (and found in yogurt) may restore immunity hurt by pollutants. A study on women with recurrent vaginal candidiasis found that acidophilus cut their infections by 300% (Annals Int Med 1992; 116:353-357.)
Another immunity enhancer, colostrum, a natural immune enhancer that promotes cellular repair (Food Res Intl. 1995, 28(1):9-16) can also help the immune system battle pollution.
Vitamin C vs Pollution
A study of vitamin's C's antioxidant properties, conducted by University of Buffalo epidemiologists, and presented at the Annual Meeting of the Society of Epidemiologic Research, revealed that people with higher levels of vitamin C in their blood serum have lower levels of a marker of oxidative stress.
"It is well known that oxidative stress (cell damage caused by free radicals) plays a role in arteriosclerosis, cancer, pulmonary disease and other chronic conditions," said Holger Schunemann, M.D. a research assistant professor of social and preventive medicine at the University of Buffalo and lead author on the study.
"In this population, vitamin C was negatively associated with oxidative stress, suggesting it may play a role in protecting against these diseases." Vitamin C is the "greatest antioxidant," says Dr. Crinnion. "It has even been shown to clear lead from the blood."
A powerful fat-soluble antioxidant, Vitamin E scavenges free radicals protecting cells from oxidative damage. Vitamin E, "reverses toxicity of various toxic chemicals," says Dr. Walter Crinnion, "it is also a stabilizer of membranes." A study published in the American Journal of Clinical Nutrition regarding antioxidant vitamin supplementation and lipid peroxidation in smokers even indicates that an antioxidant-supplemented drink can reduce lipid peroxidation and susceptibility of LDL to oxidation in smokers and may ameliorate the oxidative stress of cigarette smoke.
Dr. Glidden recommends E preferably in the form of mixed tocopherols )If you take blood thinners, check with your health practitioner.)
Unfortunately, completely avoiding toxins in today's world is probably impossible. Civilization and toxic chemicals accompany each other hand in rubber-glove-encased hand. Still, with proper attention to nutrition and supplements to keep our bodies detoxifying, we can probably minimize health difficulties linked to these undesirables.
Pycnogenol Complex - The Next Generation of Antioxidant Protection
June 04, 2005 02:14 PM
If there’s one factor that has the greatest negative impact on our health, it is the damage done to our cells by free radicals. These highly unstable molecules disrupt the biochemical processes that regulate life. Although a natural product of oxygen metabolism in the body, free radicals are also produced in vast quantities by modern technology. Our bodies’ natural defenses simply have not been able to keep up with the onslaught of these dangerous products of civilization. On the other hand, technology has offered help by identifying some of nature’s most powerful weapons against free radical attack. Source Naturals PYCNOGENOL® COMPLEX is an unprecedented combination of these extremely potent plantbased antioxidants, or Plantioxidants™. Consider them your antidote to the industrial revolution.
How free radicals are formed and their effect on the body
Oxygen both makes life, and takes life. The energy that animates us comes from the biochemical reactions that burn oxygen within our cells. And though carefully regulated by the body, this biological combustion, over time, inevitably leads to cellular damage. If oxidation is not carefully controlled, tissues are damaged faster than the body can repair them. This is caused by an excess of over-reactive, electron hungry molecules called oxidants or “free radicals,” which tend to disrupt normal cellular activity. Free radicals attack a cell’s membrane and can even damage its hereditary blueprint (DNA). Since free radicals are a natural result of certain metabolic reactions, the body synthesizes several types of antioxidant enzymes to neutralize them. In addition, we get essential antioxidants from the foods we eat. Vitamins C, E and beta carotene are the ones found most often in our diet. During this century, our environment has become a perpetual source of free radical contamination, primarily from radiation and the chemical pollution in our air, water and food. Today, we are literally overwhelmed with more free radicals than our bodies are accustomed to handling. Fortunately, science has found that certain plants contain special antioxidants that are far more powerful than the vitamins we typically get in our diet. With this knowledge, Source Naturals formulated PYCNOGENOL® COMPLEX, the most advanced combination of Plantioxidants available today in one product. Pycnogenol® is the proprietary name of a natural plant product made from the bark of the European coastal pine, Pinus maritima.
Natural protection against free radicals
Pycnogenol® Complex – A Cornucopia of Health Our knowledge of pine bark goes back nearly 500 years, to when the French explorer, Jacques Cartier, reported that a tea made from pine tree bark by Native Americans saved the lives of his crew who were dying of scurvy. Nutrition scientists have since isolated the extraordinary antioxidant compounds of pine bark. They have also discovered many other unique antioxidants throughout the plant kingdom. Plants have evolved bioflavonoids to protect themselves from free radical damage. One of the most abundant compounds in the plant kingdom, bioflavonoids are found in the pigments of bark, rinds, seeds, leaves and flowers.
Natural antioxidants in Pycnogenol® Complex
The active ingredients of Source Naturals PYCNOGENOL® COMPLEX are derived from a diverse range of nature’s plenty: pine bark, green tea, turmeric spice, rosemary, grape seeds, milk thistle seeds, bilberries, hawthorn berries and ginkgo leaves. Each of these Plantioxidants is an exceptional free radical scavenger, and each has a tendency to concentrate in a different organ of the body, thus providing targeted protection. And since their primary function is to capture free radicals, these Plantioxidants free up vitamin C, so it can perform its many other vital functions.
Defense Plants The two headliners of Source Naturals PYCNOGENOL® COMPLEX are the pine bark extract, Pycnogenol®, and an extract from grape seeds, Proanthodyn™. Their unsurpassed antioxidant activity – up to 20 times that of Vitamin C and up to 50 times that of Vitamin E – comes from a high concentration of proanthocyanidins.
Why Pycnogenol® Complex is formulated with extracts of pine bark and grape seed
These highly bioavailable flavonoids are able to cross the Blood-Brain Barrier, and can stay in the bloodstream for up to 72 hours. Few other nutritional antioxidants cross this barrier, and none do it as well. Proanthocyanidins therefore offer the brain and central nervous system unparalleled antioxidant protection. In particular, proanthocyanidins may help reduce the formation of lipofuscin, a brown waste material made of free radical-damaged proteins and fats. Over time, lipofuscin deposits form in the brain, heart, and skin. The “age” or “liver” spots that develop on the backs of some elderly peoples’ hands are made of lipofuscin. Because they’re rich in unsaturated fatty acids, cell membranes are the primary site of free radical attack. Proanthocyanidins are able to protect against both water- and fat-soluble free radicals. Also, their chemical structure is incorporated within cell membranes, making proanthocyanidins very effective in preventing damage to the cell’s interior. This is vital, because if a cell’s DNA is disrupted, it could lead to the abnormal reproduction of that cell. For many years now, Europeans have used pine bark and grape seed extracts to maintain vein and capillary health. Proanthocyanidins support the circulatory system by helping to keep collagen and elastin, the essential constituents of vessel walls, from breaking down during times of imbalance. And most importantly, proanthocyanidins can help prevent the oxidation of LDL cholesterol in the bloodstream. Scientists now recognize that it’s not cholesterol itself, but the oxidation of cholesterol that can be problematic.
How Plantioxidants benefit different organs in the body
The Power of Diversity
In addition to the broad protection offered by Pycnogenol® and Proanthodyn, Source Naturals PYCNOGENOL® COMPLEX offers an outstanding array of other Plantioxidants. Each has unique abilities to protect the body from oxidants. For several thousand years, Green Tea has been enjoyed in the Orient, not only for its taste, but also as a health tonic. Upon analysis, it contains several strong antioxidants, called Polyphenols, with exceptional free radical scavenging abilities. Polyphenols have been shown to be over 200 times more effective than vitamin E in preventing oxidative damage to brain cells. Source Naturals uses a potent extract of green tea that concentrates 2,000 pounds of fresh green tea leaves into one pound of finished product. This extract has been awarded 30 patents for its protective effects. The ancient Ginkgo Biloba tree has long been prized for its beneficial qualities. Like proanthocyanidins, ginkgo’s compounds are able to cross the Blood-Brain Barrier, and support cell membrane and capillary integrity. Its particular antioxidant constituents have been associated with superior oxygen transport to the brain. This is important because the brain uses 20% of all inhaled oxygen. Source Naturals PYCNOGENOL® COMPLEX uses a superior 50 to 1 extract, providing 24% Ginkgoflavoneglycosides and 6% Terpenoids. Bilberries were first studied for their capacity to heighten visual acuity in normal subjects under poor light conditions. In fact, to increase their night vision, RAF pilots ate bilberry jam during WW II. Its antioxidant compounds, Anthocyanosides, have an affinity for delicate eye tissues, where it quenches free radicals and supports capillary strength. Source Naturals utilizes a standardized bilberry extract with 25% anthocyanosides, 80 times more potent than regular bilberry.
The wide range of natural antioxidants in Source Naturals PYCNOGENOL® COMPLEX
Milk Thistle Seed Extract has been researched and used for over 20 years in Europe. Its antioxidant compound, called Silymarin, has a special preference for the liver. It’s one of the few nutrients that can support the liver’s natural regenerative processes. By enhancing DNA activity, liver cells can regenerate up to five times faster. Turmeric Extract contains 95% Curcumin, the active ingredient of this traditional East Indian spice. Curcumin promotes the body’s own production of antioxidant enzymes, including glutathione peroxidase, an important protector of the liver. Curcumin also increases the production and secretion of bile, which is used to remove cholesterol from the body. Quercetin has been well-researched for its free radical scavenging activity. Because of its ability to stabilize cell membranes, quercetin helps prevent damage and discomfort from reactionary (histamine- and leukotriene-related) processes in the body. Source Naturals quercetin has been isolated from plant sources. Rosemary and Hawthorn Berries both contain bioflavonoid antioxidants that have the unique ability to neutralize the hydroxyl radical, a particularly dangerous type of free radical. Hydroxyls are produced by exposure to excessive radiation and pollution from burned fossil fuels. The body has no innate defense system against it. Vitamin C is one of the most active and abundant antioxidants in the body, so it must be frequently replenished. Since it works in conjunction with bioflavonoids, each tablet of Source Naturals PYCNOGENOL® COMPLEX contains 500 mg of vitamin C, bound to Magnesium for increased bioavailability.
A World of Help
As we better understand how free radicals affect our health and well being, it’s important that we take advantage of the wonderful protective qualities found in certain plants. These Plantioxidants provide the appropriate means to counteract the destructive effects of excessive free radicals, which have become part and parcel of modern life. Source Naturals PYCNOGENOL® COMPLEX brings the diverse and concentrated power of the plant world into your world of wellness.
Menopause Multiple - Eternal Woman
June 03, 2005 05:54 PM
Menopause happens to all women, but affects each woman uniquely. For some, the end of fertility (and the end of concerns about contraception) brings a sense of freedom. For others, it is a time of troublesome symptoms or perhaps the need for certain lifestyle adjustments. Menopause is a bridge to a point in life when many women report feeling more confident, empowered and energized than in their younger years. MENOPAUSE MULTIPLE is a Bio-Aligned Formula™ that helps bring alignment to a range of interrelated body systems: hormonal regulation, bone metabolism, cardiovascular health, energy generation and circulation.
After menopause, the ovaries no longer secrete two critical steroid hormones in the amount or pattern characteristic of a regular menstrual cycle. These two hormones are estrogen and progesterone. The transition from regular ovarian function to its absence is often called the perimenopause or perimenopausal transition. The time involved can range from one to 10 years. More than one third of the women in the United States, about 36 million, have been through menopause. With a life expectancy of 81 years, a 50-year-old woman can expect to live more than one third of her life after menopause. Low estrogen levels are linked to some uncomfortable symptoms in many women. The most common and easy to recognize symptom is hot flashes -- sudden intense waves of heat and sweating. Some women find that these hot flashes disrupt their sleep, and others report mood changes. Other symptoms may include irregular periods, vaginal or urinary tract infections, urinary incontinence (leakage of urine or inability to control urine flow), and inflammation of the vagina. Because of the changes in the urinary tract and vagina, some women may have discomfort or pain during sexual intercourse. Many women also notice changes in their skin, digestive tract, and hair during menopause. Because the menopausal years place unique nutritional demands on a woman’s body, Source Naturals created MENOPAUSEMULTIPLE. This comprehensive formula brings together optimal amounts of the finest phytonutrients and herbs--including genistein, black cohosh, and chaste berry--plus vitamins and minerals known to support the biochemistry of mature women.
MENOPAUSE MULTIPLE is a comprehensive herbal-nutrient formula that supports the multiple, interconnected systems involved with female hormone function.
Hot flashes are related to hormone levels. As estrogen declines, FSH and LH (folliclestimulating and luteinizing hormones) increase, causing blood capillaries to dilate. This brings more blood and higher temperatures to the skin. Soy isoflavones and other herbs can mimic the effects of estrogen. Support for the adrenal glands is important since they account for most estrogen production after menopause.
During and after menopause, a woman’s hormonal balance and biochemistry change. Lower estrogen levels may affect bone density. Phytonutrients and calcium are important to maintain healthy bones in postmenopausal women. Calcium and magnesium work together in the metabolism of bone.
Heart & Circulation
Menopause increases concern for the health of the heart and circulatory system. Soy isoflavones and other ingredients may help maintain healthy cholesterol levels. To regulate homocysteine levels for cardiovascular health, vitamins B-6, B-12, and folic acid are critical.
Among its many functions, the liver has the important job of promoting hormonal balance by processing excess levels of hormones. The powerful antioxidant, N-acetyl cysteine, helps the liver detoxify chemicals and milk thistle is a liver protectant.
The fatigue that is common during menopause makes nutritional support for energy and metabolism especially important. Metabolism can influence weight, energy levels, and mood. MENOPAUSE MULTIPLE contains ingredients that support energy generation, including the advanced nutrients CoQ10 and lipoic acid and ginkgo biloba.
Antioxidants help protect the circulatory system, which is important as estrogen declines. Antioxidants also defend tissues and cell membranes in all your body systems from free radicals, which are formed during normal cellular metabolism. Some important antioxidants: vitamin E, vitamin C, selenium, zinc, and manganese all have strong antioxidant powers.
Lifestyle Tips for a Healthy Transition
Get Moving. Exercise is a powerful remedy for many menopause complaints and may help prevent future menopause-related diseases. It promotes better, more restorative sleep, and it stimulates production of endorphins, or “feel good” brain chemistry. Some women report having fewer hot flashes when they exercise regularly. Eat Well. A balanced diet low in saturated fat and high in whole grains, fruits and vegetables, with adequate water, vitamins and minerals contributes to good health. Women at perimenopause and beyond have special dietary concerns, because both heart disease and osteoporosis are greatly affected by diet. A balanced diet is also important for bone development and maintaining bone strength. Some women – especially those who are elderly and have reduced appetites, who diet frequently, who don’t consume diary products, or who have eating disorders – may not consume adequate vitamins and minerals to maintain optimal bone mass. There is evidence that the natural, estrogenlike compounds in soybeans and many other plant foods used in MENOPAUSE MULTIPLE may reduce hot flashes and vaginal dryness and increase bone density in women after menopause. Studies suggest that body cells respond to plant estrogens as if they were weaker versions of the human hormone. So consuming more of these estrogen-mimicking compounds may help compensate for the loss of estrogen naturally as women age. Prevent Bone Loss. Osteoporosis is one of the most preventable of bone diseases. Exercise maintains the strength of bones through aerobics, stair climbing, hiking, or walking. Prevention focuses on nutrition for bones, including a sufficient calcium intake of 1000 to 1500 mg/day.
Musculoskeletal System: Black Cohosh, Dong Quai, Licorice, Soy Isoflavones, Boron, Calcium, Magnesium, Manganese, Vitamins A, B-6, B-12, C, D & E, Folic Acid
Heart and Circulation: Black Cohosh, Coenzyme Q10, Dong Quai, Licorice, Soy Isoflavones, Magnesium, Vitamins B-6, B-12, & E, Folic Acid
Hormonal Regulation: Black Cohosh, Dong Quai, Licorice, Soy Isoflavones, Vitex, Vitamins B-5 & C
Liver Support: Coenzyme Q10, N-Acetyl Cysteine, Dandelion, alpha-Lipoic Acid, Silymarin, Selenium, Vitamin C, Biotin
Antioxidant Defense: Coenzyme Q10, N-Acetyl Cysteine, alpha-Lipoic Acid, Silymarin, Selenium, Zinc, Vitamins A, C & E
Energy Generation: alpha-Lipoic Acid, Coenzyme Q10, Magnesium, Manganese, Zinc, Vitamins B-1, B-2, B-5, & B-6, Niacinamide
Joint Response and Ultra Joint Response
June 02, 2005 01:01 PM
Many people are unaware of the multiple body systems involved with joint health. Source Naturals ULTRA JOINT RESPONSE™ is a Bio-Aligned Formula™ that goes deep to bring alignment to these multiple systems. It features structural building blocks, tissue production cofactors, and ingredients that aid the body’s mechanisms for soothing relief and antioxidant defense.
Joint Support Formulations
You can use ULTRA JOINT RESPONSE alone or as the core of your healthy joints program, complementing it with additional potencies and ingredients. These include: GLUCOSAMINE CHONDROITIN WITH MSM™, MSM Cream, SAME, CM COMPLEX™ Cetyl Myristoleate, and BROMELAIN. For muscle discomfort and fatigue, Source Naturals also offers you FIBRO-RESPONSE™ Bio-Aligned Formula.
ULTRA JOINT RESPONSE™: BIO-ALIGNED FORMULA
ULTRA JOINT RESPONSE uses scientifically researched ingredients and nutritive co-factors for a comprehensive approach to soothing, lubricating, rebuilding and aligning connective tissue, joints, tendons and ligaments. MSM dietary sulfur, glucosamine and sea cucumber provide structural building blocks that are necessary to help maintain the integrity of joints and connective tissue. Vitamins A, B-6 and C, zinc, manganese, and copper act as co-factors or parts of enzymes that play a role in connective tissue formation and maintenance. Various soothing herbs, rich in polysaccharides and other constituents, assist the body’s natural mechanisms for soothing relief. Finally, N-acetyl cysteine, grape seed, beta carotene, vitamin C, zinc, selenium, horse chestnut, turmeric, and quercetin support the body’s natural antioxidant response, thereby helping maintain the health and integrity of joints and tissues (specifically cell membranes).
GLUCOSAMINE CHONDROITIN WITH MSM: HOT RESEARCHED INGREDIENTS
For added support, Source Naturals offers you a formula that combines higher potencies of the most popular joint nutrients: glucosamine sulfate, chondroitin sulfate and MSM. GLUCOSAMINE CHONDROITIN COMPLEX WITH MSM provides the same amounts of chondroitin and glucosamine shown in recent research to support healthy joints—along with MSM, vitamin C, and molybdenum, for a more powerful product. Together, these ingredients promote joint, tendon and ligament flexibility and easy joint movement.
FIBRO-RESPONSE: BIO-ALIGNED FORMULA Dealing with the muscle discomfort that affects millions in our society requires more than alleviating fatigue. FIBRO-RESPONSE influences specific body systems and tissues involved in joint health and muscular metabolism. Malic acid and magnesium, supplied in the same amounts used in recent research, help support muscular energy production, along with coenzyme Q10, lipoic acid and B-complex vitamins. MSM, copper, manganese, molybdenum, zinc, vitamin C, and beta carotene support healthy connective tissue, which is essential for proper joint and muscle function. Key ingredients, including N-acetyl cysteine and Silymarin aid the liver in eliminating toxic waste from blood and tissues. Ingredients including lipoic acid, selenium, N-acetyl cysteine, and coenzyme Q10 support antioxidant defense, thereby helping to maintain tissue integrity. And ginkgo and GABA are among the ingredients that support clear focus and stress reduction.
LIFESTYLE TIPS FOR HEALTHY JOINTS: A STRATEGY FOR WELLNESSSM Healthy lifestyle habits should be part of your individual strategy for joint wellness. Watch Your Weight: Population-based studies, including the well-known Framingham study, have consistently shown a link between obesity and challenges to joint health. Excess weight causes pressure on joints, and can speed the rate at which cartilage wears down. Eat Healthy: To support healthy joints, increase your intake of omega-3 fatty acids from salmon, sardines, flax seeds or flax oil, avoid excess protein intake, and replace animal with plant proteins when possible. You should also eat lots of organically grown fruits and vegetables, and eliminate polyunsaturated and hydrogenated oils. Exercise Regularly: Regular physical activity helps lubricate cartilage, strengthens muscles around joints, and promotes weight control. An exercise program geared to joint health includes stretching, mild weight training, and low-impact aerobics. Rest and Relaxation: Regularly scheduled rest gives your body time to recover and rebuild, allowing you to make the most of your exercise program. It’s important to know when to slow down. Supplementation: In addition to the formulas described above, Source Naturals offers a range of products that can supplement your strategy for joint wellness. These include the pineapple enzyme BROMELAIN; SAMe, a natural compound formed from the amino acid methionine, which has been found to support joint comfort and mobility; and CM COMPLEX™ Cetyl Myristoleate, a fatty acid ester shown in recent research to reduce joint discomfort.