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Allercetin: Your Natural Defense Against Allergies and Sinus Issues
Date:
June 06, 2024 05:20 PM
Allergies and sinus issues can be a constant thorn in the side for many individuals. Everyday activities can feel like an uphill battle when you're plagued by congestion, sneezing, and itchy eyes. But what if there was a natural remedy that could provide relief across multiple body systems? Introducing Allercetin™ Allergy & Sinus, a Bio-Aligned Formula designed to tackle the root causes of your allergy symptoms.
Allercetin™ is not your average allergy treatment. This innovative product leverages natural homeopathic remedies to address the complex web of systems involved in allergic reactions. Unlike many over-the-counter medications that offer temporary relief, Allercetin™ provides a comprehensive approach, targeting the respiratory system, sinuses, mucous membranes, and more.
The key to Allercetin™'s effectiveness lies in its Bio-Aligned Formula. This advanced blend of natural ingredients is designed to support multiple body systems that are often affected by hay fever and other allergic conditions.
Breathing becomes a chore when your respiratory system is compromised by allergens. Allercetin™ contains ingredients that help to open up the Airways, making it easier to breathe. This can be particularly beneficial during high pollen seasons when respiratory issues are at their peak.
Your sinuses play a crucial role in trapping allergens and preventing them from entering your respiratory system. However, when they become inflamed, they can cause severe discomfort. Allercetin™ supports the health of your sinuses, promoting natural drainage and reducing inflammation.
Mucous membranes are the body's first line of defense against airborne irritants. Allercetin™ helps to maintain the integrity of these membranes, ensuring they function optimally. This reduces the likelihood of allergens causing significant irritation and discomfort.
Histamines are chemicals in the body that play a central role in allergic reactions. When released in large amounts, they can cause symptoms like itching, swelling, and redness. Allercetin™ works to inhibit the release of histamines, thus reducing the severity of allergic reactions.
A hyperactive immune system can exacerbate allergy symptoms. Allercetin™ includes ingredients that help to desensitize the immune system, making it less reactive to allergens. This not only alleviates current symptoms but can also reduce the likelihood of future allergic reactions.
When your body is fighting allergies, it can drain your energy levels significantly. Allercetin™ supports cellular energy production, ensuring you have the stamina to go about your daily activities with ease.
Using Allercetin™ is simple and convenient. Take the recommended dosage as indicated on the packaging, preferably at the onset of symptoms. Consistency is key to experiencing the full benefits of this natural remedy.
Multiple factors set Allercetin™ apart from other allergy treatments on the market. Here are some reasons why you should consider making it a staple in your wellness routine:
Don't just take our word for it; listen to what our satisfied customers have to say:
Rigorous scientific research guided the development of Allercetin™. We selected each ingredient based on its ability to alleviate symptoms and support overall well-being. This guarantees you receive a product supported by both traditional wisdom and modern science.
Living with allergies and sinus issues doesn't have to be an ordeal. With Allercetin™ Allergy & Sinus, you can take a proactive approach to manage your symptoms naturally and effectively. Why settle for temporary relief when you can address the root causes of your discomfort? Experience the transformative power of Allercetin™ for yourself. Don't let allergies hold you back any longer. Visit our website today to purchase Allercetin™ Allergy & Sinus and reclaim your life from the shackles of allergies. Take the first step towards a healthier, more comfortable life—order now!
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Date:
April 30, 2022 11:04 AM
Sinus problems are a common occurrence during the winter months. Cold weather, dry air, and allergens can all contribute to sinus congestion and inflammation. If you are looking for an over-the-counter sinus remedy that will provide relief from your symptoms, you have come to the right place! In this blog post, we will discuss some of the most effective over-the-counter sinus remedies on the market. We will also provide tips on how to choose the right one for you. So don't suffer any longer - read on for information on the best over-the-counter sinus remedies available today!
What are the most common symptoms of sinus problems?
Sinus problems are very common, and the symptoms can vary depending on the severity of the issue. One of the most common symptoms is a feeling of congestion or fullness in the sinuses. This can be accompanied by pain and pressure in the forehead, cheeks, or around the eyes. Other common symptoms include a runny nose, cough, sore throat, and fatigue. In some cases,sinus problems can also lead to fever and difficulty breathing. If you are experiencing any of these symptoms, it is important to see a doctor so that you can get proper treatment.
What are the causes of sinus problems?
Sinus problems are a common and often frustrating issue, with a wide range of underlying causes. From environmental irritants like pollen and dust to infectious agents like bacteria and viruses, there are an almost limitless number of possible culprits behind sinus troubles. Additionally, certain foods, medications, or other habits can also affect the delicate balance of mucus in the sinuses. Ultimately, understanding the various factors that influence a person's susceptibility to sinus problems is the key to effectively managing these conditions. By identifying any triggers or risk factors one can minimize the impact of sinus issues on everyday life.
What are the best natural over-the-counter sinus remedies available today?
Sinusitis is a condition that affects the sinuses, the small, air-filled cavities located around the nose and eyes. It occurs when these cavities become inflamed, often due to a viral infection. Sinusitis can be extremely painful, causing congestion, headaches, and facial pain. While there are many over-the-counter medications available to treat sinusitis, some people prefer to use natural remedies. One popular natural remedy is steam inhalation. This involves inhaling steam from a pot of boiling water or from a humidifier. The steam can help to loosen mucus and reduce inflammation. Another popular option is saltwater irrigation, which involves using a neti pot or nasal sprayer to rinse the sinuses with warm saltwater. This can help to flush out irritants and ease congestion. Natural remedies are often safe and effective, making them a good option for treating sinusitis.
Luckily, there are a number of effective natural over-the-counter remedies that can help to alleviate symptoms like congestion and inflammation. For example, nettle leaf is a popular herb with a long history of use in naturopathic medicine. Rich in minerals and anti-inflammatory compounds, it can help to clear out toxins from the sinuses while also soothing swelling and reducing pain. Other possible remedies include quercetin, an antioxidant found in many fruits and vegetables that has been shown to have antihistamine effects, and anti-histamine formulas containing herbs or plant oils that naturally regulate histamine levels. Ultimately, the best remedy for your individual sinus issues will depend on your specific symptoms and preferences.
Nettle leaf to relieve sinus allergy symptoms.
As we have said, allergies are a common problem, affecting millions of people worldwide. They can cause a range of symptoms, from mild sniffling and sneezing to severe congestion and difficulty breathing. Many people rely on over-the-counter medications to alleviate their allergy symptoms, but these drugs can have undesirable side effects. Fortunately, there are natural alternatives that can be just as effective in relieving allergy symptoms. One such remedy is nettle leaf. Nettle leaf has been used for centuries to treat a variety of ailments, including allergies. It works by inhibiting the release of histamine, which is one of the main compounds that triggers allergy symptoms. In addition, nettle leaf has anti-inflammatory properties that can help to reduce congestion and swelling. If you're looking for a natural way to relieve your allergy symptoms, nettle leaf may be worth trying.
Quercetin and allergies
Quercetin is a potent antioxidant that has been found to be effective in preventing and treating a variety of health conditions, including allergies. Many people are familiar with quercetin as an antihistamine, an effect that is due to its ability to inhibit the production of "histamines" in the body. Histamines are the chemicals responsible for triggering allergic reactions such as watery eyes, runny nose, itching, and sneezing. By blocking their production, quercetin can effectively reduce or even eliminate these symptoms. Furthermore, quercetin has also been found to strengthen lung function by reducing inflammation in the Airways and protecting against oxidative damage. Overall, quercetin may be an ideal natural remedy for alleviating allergy symptoms.
Cayenne and Allergies
Cayenne is a popular spice that is prized for its pungent, spicy flavor. In addition to being used in cooking, however, cayenne has also been shown to be an effective remedy for certain allergies. Studies have found that the active ingredient in cayenne, capsaicin, can help to block inflammatory responses in the body and neutralize histamine, the chemical that triggers allergic reactions such as sneezing and watery eyes. As a result, regular consumption of cayenne may help to reduce allergic symptoms and improve overall quality of life for those affected by allergies. Whether through fresh peppers or cayenne powder or supplements, incorporating this powerful spice into your diet may be a great way to treat your seasonal allergies naturally.
Is there a supplement that combines them all? Yes, Solaray Sinus Source?
Yes, there is a supplement that combines all the key ingredients typically found in nature-based sinus cleansers and decongestants. This supplement is called Solaray Sinus Source, and it contains a combination of three active ingredients: nettle leaf, quercetin, and cayenne pepper. Each of these ingredients has been shown to provide natural relief from sinus problems, helping to reduce inflammation, congestion, and other unwanted symptoms. By combining these powerful botanicals into one convenient formula, Solaray Sinus Source provides a safe and effective way to support healthy sinuses. So if you're looking for a natural solution to your sinus woes, look no further than this powerful blend!
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Date:
April 19, 2019 01:43 PM
Ginger oil is made from the versatile kitchen spice, and provides a wide variety of antibacterial, anti inflammatory and other health benefits. Ginger can help clear out your airway and soothe a troubled digestive system. You can also apply it topically to help relieve muscle and joint aches. Ginger oil is easy to make at home, and it retains the spicy taste of its main ingredient, making it an excellent addition to baked goods and other dishes. Key Takeaways: "Ginger is one of the healthiest spices you can add to your diet and all its healing properties are credited to the presence of the bio-active compound gingerol." Read more: https://food.ndtv.com/food-drinks/ginger-oil-fighting-inflammation-and-other-healing-health-benefits-of-the-oil-2000177
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Date:
February 27, 2019 09:57 AM
A recent Annals of Saudi Medicine article suggests that black cumin can have significant benefits for the respiratory health of people with asthma. Researchers from Saudi Arabia’s Imam Abdulrahman Bin Faisal University conducted a clinical trial involving 76 asthma patients. They supplemented the patients’ maintenance inhaler regimens with either one gram or two grams of black cumin, or else a placebo. Subsequent evaluation found that those who had received any amount of black cumin supplementation saw better improvement in lung function relative to those who did not receive any. Key Takeaways: "Research suggests that black cumin, also known as Nigella sativa, can help people with asthma." Read more: https://www.naturalnews.com/2019-01-20-healing-potential-of-black-cumin-for-asthmatic-patients.html
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Date:
November 29, 2018 12:32 PM
Your lungs are the key to maintaining a positive breathing tunnel in your body. Making sure your body gets enough oxygen at every minute of the day is obviously very important. Some people abuse their lungs to a point where it is very hard for them to be healthy from that point on. As a result, there are a ton of people who suffer from asthma. It is a disease that there is no cure for but there are some oils that can help treat it. Key Takeaways: "Peppermint essential oil has decongestant and antihistamine properties that relieve asthma attacks. Exposure to allergens such as dust mites and pollen trigger your body to release histamines, which in turn trigger asthma attacks." Read more: https://www.healthnutnews.com/this-is-what-happens-with-your-lungs-when-you-diffuse-essential-oils/
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Date:
September 05, 2017 12:14 PM
There is a golden honey mixture that is the strongest known natural antibiotic. Honey is very rich in antioxidants as well as essential vitamins. It has regenerative properties and it fights against the negative effects of free radicals. It strengthens the tissue and increases the number of antibodies. It helps to reduce mucus in the airways as well. Turmeric is a great antibiotic as well. It is a natural painkiller. It balances inflammation in our tissue. Key Takeaways: "Anti-inflammatory medication is used in order to eliminate excessive inflammation in the body, caused by our immune system as it defends itself from harmful pathogens." Read more: https://www.youtube.com/watch?v=ol_kw9FNceI
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Date:
March 20, 2017 11:44 AM
You can treat your allergies with weed. It can help with seasonal allergies. This is good news for people that like weed. It has already been known for some time now, that weed helps with asthma symptoms. There is no doubt that weed has some very great properties. It's not just a subject for young people that do it for recreation, or congressman anymore. Key Takeaways: "CBD is the compound in cannabis that does not get you high, meaning there’s no reason it can’t serve as a regular treatment for these issues." Reference:
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Date:
April 19, 2014 05:48 AM
Respiratory tract The fact is that we cannot live without oxygen. Our respiratory tract acts as the link or rather the Airway between the outside environment and our lungs. This explains why it is of much importance to ensure optimum health for our respiratory tract. The respiratory system being very sensitive, our lung health is largely enforced by the cilia, which keeps bacteria, dust particles and viruses at bay. Benefits of ivy Ivy (Hedra helix) is a plant that has been clinically proven an excellent cough medicine especially for those with asthma or bronchitis. The Ivy leaf extract has various modes of action. As an expectorant. This mode of action acts in that it helps bring mucus up from the lungs. This ensures that there are minimal problem ingredients entering the lungs. As a mucolytic.This means it, helps dissolve mucus. Some types of coughs thicken mucus leading to blocked tracts. As a bronchial dilator. This means that the medicine helps in opening up the air passageway for easier breathing. The Ivy leaf extract has been termed as a solution to painful coughing though it does not really block out the action. Through the mucolytic action, it dissolves the mucus thus easing constriction. As opposed to other solutions, the Ivy is tolerable to children thus making it suitable for both adults and children. Most importantly, it works efficiently with all age groups. Where it grows. The Ivy can be described as a climbing plant, evergreen and fast growing. It grows in woodland and hedgerows especially in winter gardens. It is not a threat to healthy trees and requires regular trimming to avoid it becoming too heavy. In a close up, lung health is paramount for easier and safe breathing. Ivy leaf extract is a medicine that we count can on for excellent results. If pregnant or nursing, consult health care practitioner before use.
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Date:
March 05, 2014 08:08 AM
Celadrin In clinical studies, Celadrin cream application has been demonstrated to lessen joint torment in less than 30 minutes. This quite viable, all-common mitigating medication holds a protected mix of specific greasy acids and some menthol's to help reduce torment in the joints, advertise joint flexibility and grease and to help smooth sore muscles. How can it function? A long time involving usage in addition to strenuous action can certainly reduce the mobility of your joint parts in addition to deterioration your water that ones your joint parts via pain, ultimately producing osteoarthritis. Celadrin gives remedy in addition to rejuvenation of those joint parts. The item functions by lubricating your mobile walls, so improving your extra padding power involving joint parts in addition to bones. Fat have also been proven to avoid your routine involving redness, making an effort to relieve pain within the joint parts in addition to muscular tissues. When you suffer from muscle mass in addition to joint, Celadrin ointment affords the relief you have to make it through your worktime. Analyzed from prime educational facilities in addition to major medical stores, Celadrin ointment gives relief in order to aching muscular tissues in addition to joint parts. It provides lubrication in addition to works just like a "cushion" among joint parts in addition to cartilage. Rigid joint parts in addition to pain are generally as a result of bad lubrication. Celadrin Product gives remedy in order to fatigued, aching muscular tissues in addition to joint parts. The majority of people think outcomes inside a half-hour. Scientifically Efficient Joint pain Pain relief The results involving human being specialized medical trial offers assist the effectiveness of Celadrin ointment. In a double-blind placebo-controlled trial run released within the Journal involving Rheumatology, forty five participants along with uncomfortable knee joint parts - ingested both Celadrin Mutual Proper care Pain relief or even a placebo ointment to put on topically double every day intended for 1 month. Members have been evaluated on several orthopedic procedures involving development. At the conclusion in the examine, your analysts known that the Celadrin had been a simple yet effective therapy intended for enhancing knee mobility, chance to ascend/descend stAirways, chance to surge via seated, go in addition to have a seat, in addition to unilateral sense of balance. No changes have been welcomed in your placebo class. Another examine involving 28 people who have arthritis in the knee additionally revealed major improvements throughout knee function, range of motion in addition to pain decrease in a matter of a single week involving utilizing Celadrin ointment.
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Date:
December 24, 2012 07:58 AM
Forskolin is the chemical substance extracted from the root of a plant called coleus forskolin also known as Indian coleus plant. This plant originated in India and its part of mint family. This herb is used to treat various health conditions. One of the benefits of this herb is its great effectiveness in losing weight. For those people who love looking good, then this product can be of great help. This herb can greatly help wit the reduction of excess fat; this helps in speeding up the process of losing weight. Forskolin can work in two days. It works first through stimulating lipolysis and then breaking down the lipids containing fats. This is takes much less time compared to other traditional methods since it raises the cAMP production levels in patients. CAMP regulates glycogen, sugar and lipid. Scientists have proven that this herb can be very beneficial to obese patients. Stimulates Thyroid function Secondly, Forskolin helps in losing weight through is ability to increase the production of thyroid hormone levels. When thyroid production is increased, our metabolism rate increases which leads to weight loss. Typical dosage is 25 to 60mg of forskolin herb per day. This is divided into 2 or 3 doses. Weight loss can be experienced within a few weeks of regular use of this herb. This herb also helps in lowering blood pressure, therefore preventing blood clots. An improved blood flow helps maintain a healthy heart. This herb also helps in maintaining healthy lungs. Forskolin is also used in treatment of eczema and psoriasis. It's also beneficial to asthma patients by aiding in relaxing the Airways, this helps in respiration process. This product has no known side effects, it can also be taken along with other caffeine's; this provides a boost in the stamina. However, make sure you see your doctor for proper guidance on how to use this product.
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Date:
March 10, 2012 12:00 AM
Cordycep mushrooms
Cordycep mushrooms have been receiving a lot of hype lately, as they are said to have many compounds that can benefit ones health. Cordycep mushrooms have been used for 1500 years in ancient Chinese history, and was proven to benefit a variety of factors. However, it seems as if people are having a tough time when it comes to looking for them, as they are known for being in natural habitats. Cordyceps itself is a type of fungus, and it includes over 400 kinds of described species. Cordyceps are abundant in tropical areas, as they tend to thrive better in humidity and high temperature. Cordyceps have also had an extensive history of being a medicinal fungi. Cordyceps are not really known in the Western world, as scientists have not been able to study it properly yet. However, since China has been studying the fungus for some time now, some of this fungus' secrets were already unfolded. The main reason to why Cordyceps have received so much attention is that the History Channel stated that if someone finds an ounce of Cordyceps, you will be given 900 dollars.
The Benefits To Taking A Supplement Of Cordycep.
One benefit to taking a supplement of cordycep is that it dilates the Airways of your lungs, allowing more oxygen to your lungs. Cordyceps are also known for fighting the means of womens infertility. It also enhances mens sexual performance and fuction by stimulating the sex hormones. Cordyceps helps in building muscle and even improve ones physical performance as well. It also has the capability to reduce the effects of fatigue, and has anti-aging properties as well. These help in strengthening the liver and kidney, as it improves the natural flow of your blood. They help strengthen and even enhance your immune system because it has the capability to increase and improve a huge amount of natural killer cells.
Where Can You Find Cordyceps In Nature Habitats?
Cordyceps can be found in a huge array of areas such as Australia, Asia, Europe, North America, China, and Russia. However, they tend to grow in the South areas of tropical places. The best places to look for cordyceps would have to be in the areas where ants climb the moment before they pass away. Those areas are tree branches and the bottom of tree leaves. They can also be found in tropical forests as well. The fruiting body of a Cordycep sort of has a grass-like appearance, making it easy for them to be spotted. They also kind of look like worms, and though they are technically mushrooms, in wild areas, they can grow on plants, insects, caterpillars, and a variety of other fungus' as well.
Cordyceps can be found in a huge array of areas, so you must learn and know exactly what they look like to actually find a couple ounces. Cordyceps are said to be worth a fortune, and its value has even increased throughout the years. Even if it's tough to find cordyceps, at least the reward that you are given is decent.
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Date:
February 13, 2012 01:57 AM
Quinoa is a gluten free seed rich in dietary fibers with creamy, fluffy and slightly crunchy texture. Its taste is somewhat nutty when cooked. It belongs to the family of spinach, beets, swiss chard and lamb's quarter.It is a complete protein grain with all the essential amino acids. There are nine essential amino acids known as the building blocks of protein. Amino acids help in building strong muscles and nourish the nerves.It is also rich in essential minerals such as manganese, magnesium, phosphorus, copper and iron.
Quinoa is technically a seed, not a grain of a goose foot plant. The name quinoa came from Greek words chen which means goose and pou which means foot. This is because the leaves of the plant of quinoa seeds resemble the webbed foot of a goose.
Quinoa has been cultivated as early as the 12th century by the Incans, the ancient people of South America. They referred to quinoa as the "mother seed",considered as a sacred grain and gold of the Incans.They believed that it is a gift from gods that possesses enhancing properties.The emperor ritually planted and sowed the first quinoa seed of the season using his golden taquiza, a shovel like planting stick. Quinoa gives energy and increases oxygen to the relay teams of bare footed running messengers who lived in the mountains with an altitude considered high enough where oxygen level is reduced.This is because they were holding ash from quinoa plant and cocoa leaves. This combination increases oxygen in their body to sustain the runners increasing need for oxygen. In can armies also used quinoa to energize their body from frequent marching for days. Quinoa is part of the native Indian diet to increase their resistance to prevail over harsh living condition in the high mountains.
Today quinoa is making its name popular in the industry of wonder foods.It is so high in protein that builds and nourishes muscle tissues. It is used to treat people with migraine, diabetes and atherosclerosis. It is a good source of magnesium that relaxes the blood vessels. Magnesium reduces attack of migraine by improving blood and oxygen distribution to the brain.
Magnesium combined with high dietary fiber found in quinoa helps in maintaining healthy blood pressure and prevents cardiovascular diseases. Fibers absorb and eliminate bad cholesterol.It prevents plaque that blocks the arteries and enhances blood circulation.This process prevents atherosclerosis, the hardening of the arteries due to fat deposits and plaque buildup that narrows the arteries.
Quinoa is rich in anti oxidants that shields each cells from getting damaged caused by free radicals, pollution, alcohol and medication. It boosts the immunity and increases resistance from stress. Anti oxidants and fibers prevent risks of cancer and diabetes.Obesity and overweight are the most common risk factor of diabetes. Fibers remove toxins and excess fats, improve digestion and maintain healthy body weight to prevent diabetes.While antioxidants enhances cell regeneration and repair. This process lowers risks of cancer.
Quinoa is highin insoluble fiber thatprevents gallstones and helps in cleansing the liver. Whole grains like quinoa reduce asthma, allergic cough and wheezing in children. The protein in quinoa strengthens the muscle tissues of the air passage, thus prevents inflammation that narrows the Airways of asthma patients.
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Date:
December 22, 2011 07:59 AM
One of the most discomforting things that anyone can experience is allergic reactions. In more severe cases it is a big concern health wise and can easily be a cause of death but in less severe cases it can be a cause of so much annoyance. Severe cases can shut your throat in a matter of minutes and keep you from breathing and the more annoying once are the ones sometimes that are caused by dust or cat hairs as a couple of examples and it will cause you to sneeze all day long or trigger a running nose or something of that sort.
Antihistamine
Simply put, it is a type of drug that is used to fight allergic reactions and it covers the minor to the more life threatening conditions. Each type of reaction also has a matching type of antihistamine however the bottom line is that it does one thing and that is to do what its name suggests, to counteract the chemical in our body known as histamine. This is the chemical which is released by our immune system when an allergen which is defined as a harmless external chemical, is exposed to the body. In a way an allergic reaction is our immune systems way of protecting us the problem is, in this case it is a false response. Histamine is a very powerful stimulant and has the ability to cause so much irritation within the body. The symptoms depends on the severity of the reaction, it ranges from itching, watery eyes, skin rashes, runny nose and the most life threatening one is closure of Airways.
Quercetin
It is a pigment from plants which are found mainly in onions, berries, apples and grapes. It is considered a flavonoid. Quercetin has been used in many countries for many years to improve blood vessel health naturally and has been part of natural medicine for years now. It also has been shown in some studies to have good potency as an antioxidant and has been shown to have the ability to reduce the risk of oxidative DNA damage which is a precursor to cancer.
Bromelain
This refers to the plant extract which is obtained from pineapples to put it in simple terms. This substance is known to be protease enzymes as they initiate the digestion of protein which is its main function. It also has been shown on various studies that it has antiviral capabilities. However its best known medical use is for treatment of arthritis and other inflammation based illness.
Both as antihistamines
Quercetin, aside from the health benefits mentioned above has been shown to be able to fight against allergic reactions and bromelain helps with its absorption so if put together it could be a potent one two punch against the common cold or flu but for severe cases against severe allergic reactions further research needs to be done to cement the idea that these substance can take the place of antihistamines.
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Date:
May 08, 2009 10:00 AM
L-Cysteine is what is known as a non-essential amino acid, meaning that it can be biosynthesized by the body and hence not an essential part of your diet. Due to its possessing a thiol side chain, it is termed a hydrophilic amino acid with an affinity for aqueous systems. Because of this it is relatively highly reactive, and is therefore an important component of a large number of enzymes and proteins.
Although, after all, it is not an essential amino acid, deficiencies can occur in the young and in the old, and also in those suffering certain metabolic diseases. Dietary sources include high-protein foods such as chicken, turkey, pork, dairy products and vegetables such as cereals, broccoli, garlic and onions.
The biochemistry of this amino acid begins with another amino acid known as serine, and also methionine. The latter is fist converted to homocysteine, which is then combined with serine to form cystathionine. This is then converted into cysteine and alpha- ketobutyrate. The thiol group is highly reactive and gives cysteine its biological properties.
L-Cysteine possesses strong antioxidant properties due to the thiol group which easily undergoes redox reactions. However, it is for its detoxification effect on the body that the amino acid is mainly taken as a supplement. It is, therefore, these properties that we shall discuss first.
Cysteine can reduce the toxic effects of alcohol, such as a hangover or the more serious liver damage. The by-product of alcohol metabolism that does most damage and is responsible for the majority of the negative after-effects of excessive alcohol consumption is acetaldehyde. L-Cysteine converts acetaldehyde into the more acceptable acetic acid, and so prevents the aldehyde from having too much of a negative effect on your health and well-being. However, the results obtained from such studies have been from animals only, and the therapeutic effects of cysteine have not yet been tested on humans.
What has been tested and is known is that L-cysteine is effective in the detoxification of heavy metals in the body. A common source of heavy metal toxicity is mercury from amalgam fillings in the teeth. Although the Environmental Protection Agency (EPA) declared in 1989 that dental amalgams are a hazardous substance under the Superfund law, many people still have them in their mouths.
The thiol group and L-cysteine has a high affinity for mercury and other heavy metals, as previously stated, and a supplement can be used to remove from the body any mercury leached from mercury-based tooth fillings. It can also be used to bind to copper, lead and cadmium. Lead and cadmium are particularly toxic to the human body, and even though lead is no longer used in plumbing or paints, and cadmium in toys or paints, there are still many sources of these two heavy metals available that can lead to human toxification.
An L-cysteine supplement can be used to remove these heavy metals from the body. Any proteins containing cysteine will tightly bind heavy metals such as lead, cadmium, molybdenum, cobalt and mercury, and allow them to be excreted by the body in the usual fashion. This direct involvement in heavy metal detoxification is a very useful property of this amino acid.
Another detoxification application of L-cysteine is in direct involvement in protecting cellular glutathione levels, and also the prevention of the death of liver cells by acetaminophen poisoning. The latter is of particular interest to many people since acetaminophen is better known as paracetamol, and since this is a freely available over-the-counter drug, overdoses are not unknown. The result of an overdose is the necrosis of liver cells, with eventual liver failure and death.
The treatment of choice is N-acetylcysteine. If used within 10 hours of the overdose it is extremely effective, and even from 16 to 24 hours it is better than other controls. It is believed that the acetylcysteine liberates cysteine which, when available to the liver, enables the biosynthesis of glutathione. Glutathione can then maintain the production of the fifth metabolite required for the specific detoxification of the paracetamol/acetaminophen.
L-Cysteine is also an essential component in the biosynthesis of coenzyme A, an enzyme essential for the production of energy from fats and carbohydrates. It is also a very important component of hair, from which it is commercially produced. Without an adequate intake of L-cysteine the growth of healthy hair would not be possible.
There are several supplemental uses of L-cysteine including the treatment of bronchial conditions for which the amino acid can help to liquefy and clear mucus from the Airways and lungs. It is also used to protect against side effects of chemotherapy treatment of cancers and for medical treatments for excessive exposure to radiation.
However, there are certain situations in which L-cysteine should be avoided when at all possible. Diabetics should not use it, and neither should those suffering from cystinuria, whereby large quantities of amino acids, including cystine, are excreted in their urine. L-cystine, incidentally, is formed by oxidation of L-cysteine.
Paradoxically the amino acid is one of the several hundred additives made to tobacco by the cigarette companies. Although, as with the majority of tobacco additives, its purpose is unknown there are two possible reasons for its inclusion. L-Cysteine is a known expectorant, so it could be added to promote the expectoration of mucus in the lungs which is promoted by smoking, and it also increases the production off the antioxidant glutathione that is depleted in smokers.
There are several other non-medical uses for the amino acid, but it is for is its detoxification properties that it is most used as a supplement. However, because it is largely derived from human hair or duck feathers, it may not be classed as kosher or halal in spite of many claims made to that effect, though the more expensive source of microbial fermentation from corn sugar can be.
The substance is recognized as safe by the FDA, and must be labeled as L-cysteine when it is present in a preparation intended for its therapeutic effects. Keep in mind however, that it should be avoided by diabetics.
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Date:
November 25, 2008 12:08 PM
According to the 2006 National Health Survey from the National Center for Health Statistics, it is estimated that about 17.6 million adult Americans suffer from hay fever, with 6.8 children also suffering. Even more, physicians state that more than 11 million office visits are by patients seeking relief from hay fever, which is also known as allergic rhinitis. Symptoms of hay fever include itchy eyes, runny nose, congestion, and an endless amount of sneezing. All of these symptoms are caused by an overacting immune response to a variety of possible triggers, which include pollen from plants, dust, dust mites, airborne pollutants, mold, and pet dander.
Hay fever is marked by inflammation of mucous membranes in the eyes, throat, ears, sinuses, nose, and lungs. Although the development of inflammation in allergies is complex, one of the most influential factors is immunoglobulin E (IgE), which responds to protein allergens. Although there is a genetic component to susceptibility to allergic response to certain triggers, the focus of allergy relief is on the events that occur as a reaction.
Various natural products offer allergy relief by targeting the factors in allergy pathology. Similar to other areas of immune health, fruits and vegetables are suggested for the vitamins, minerals and antioxidants that they provide. Vitamin C is a major antioxidant in the Airway surface liquid of the lungs; therefore, it can severely impact allergies and asthma. Low levels of vitamin C have actually been associated with asthma in both adults and children. Also, low levels of vitamin E have been associated with asthma and other wheezing illnesses. Combining antioxidant ingredients also provides additional relief. Therefore, by combining vitamins C and E with the antioxidant NAC, pollen-induced Airway inflammation is inhibited by blocking ragweed oxidases which cause oxidative stress and inflammation in the Airways.
On its own, NAC reduces mucous viscosity and protects against lung tissue damage. According to scientists, lycopene may also be beneficial. As far as minerals are concerned, both magnesium and zinc have been proven to help. Quercetin has both antihistamine and anti-inflammatory properties, allowing it to inhibit the release of histamine in nasal mucosa of allergic patients. Glucomannan was shown in a study to suppress allergy symptoms, while CLA reduces allergy symptoms such as sneezing.
One of the best natural remedies for allergies is comprised of botanicals such as licorice root, skullcap, pine bark extract, and butterbur. Licorice root offers anti-inflammatory activities along with aide in fighting IgE allergic reactions, while skullcap can restrict inflammatory cytokine production. Pine bark extract blocks the release of allergy troublemakers in the body even better than a known pharmacological histamine inhibitor.
Similarly, butterbur has abilities in blocking histamine release by IgE-sensitized mast cells and relieving allergy symptoms as effectively as drugs without the drowsy side effects. Although allergies are widespread and disrupt the daily lives of many people, they strike one out of every four Americans, affecting six times more than cancer. The mechanisms of allergic reactions in the body, especially those in the upper respiratory system, are becoming more and more well-known.
Natural products are available that can help to address these mechanisms, along with the mediators that produce the inflammation and symptoms that allergies create. Natural vitamin supplements are available at your local or internet health food store.
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Date:
April 29, 2008 10:49 AM
Butterbur extract is taken mainly from the rhizome, root and leaves of the butterbur, a member of the daisy family. They are very hardy and have creeping underground rhizomes and large leaves like those of rhubarb. Another name given to it is the sweet Coltsfoot, and they generally grow in the temperate climates of Europe, North Africa and South west Asia. They like damp conditions, specifically marshes and ditches, and also riverbanks where there are always plentiful supplies of moisture.
It has been used by Native Americans for headaches and inflammation, and has been shown to be an effective remedy for hay fever and to provide relief from painful menstrual cramps. Butterbur has also been used throughout the middle Ages to treat fever and the plague, and has been recorded in the seventeenth century as being used for asthma, wounds and coughs. However, one of its most important applications is in restore bladder function in the incontinent and semi-incontinent.
Urinary incontinence is typified by an unusually high frequency of urination – more than 8 times a day, an immediate strong urge to pass water or leaking and involuntary urination. Any two of these three indicates urinary incontinence. As people age their bladders become smaller, and by definition the periods between urination will reduce. This does not, however, suggest that bladder size is the cause of urinary incontinence.
Urination is caused by the contraction of the smooth layered muscle that surrounds the bladder, called the detrusor, a contraction in turn caused by neurons both in the brain and in the detrusor itself. This naturally contracts and expands according to the volume of urine in the bladder, and once the bladder is about half full the brain will tell you that the detrusor is ready to contract to expel the urine. However, if the time is not convenient, the cortex will suppress this desire until a more convenient time.
In incontinence, the desire is suppressed but the neurons still fire to contract the detrusor, expelling urine at inconvenient moments. Butterbur contains the sesquiterpenes petasin and isopetasin, which are known to reduce spasms in smooth muscle tissue and in vascular walls. It can therefore be used to control the involuntary spasms that cause urine leakage or expulsion against the patient’s wishes. These sesquiterpenes are at highest concentration in the roots of the plant.
The effect that the sesquiterpenes have in inhibiting the synthesis of leukotriene in leukocytes tends to support this effect, since leukotrienes can cause contraction of vascular and smooth muscle tissue. Not only this, but the spasmolytic effect could also be explained by the inhibition of cellular calcium caused by the petasin isomers.
Many studies have indicated that the effectiveness of butterbur extract is also useful in the prevention of migraines. There has been a lot of research carried out on the use of butterbur extract on migraine sufferers, and the effective dose appears to about 75 mg twice daily. There is little evidence of it being a cure but as a prophylactic there appears no doubt of its efficacy: there have been too many positive results against placebos for its effect to be deniable.
It is significant that leukotriene can cause constriction of the small blood vessels in the veins, and so affect the flow of blood. Butterbur, in inhibiting its biochemical production, helps to keep these blood vessels open. Lekotrienes are also important components of inflammation, and altogether it appears that whatever the real cause of migraine, the petasin isomers in butterbur have an effect in inhibiting its initiation. Add to that the potential reduction in calcium content that can cause blood vessels to become less flexible, and the argument for its effectiveness is both irrefutable and well explained.
In one example of such a double blind study that is representative of many, a group of patients given 50 mg butterbur extract twice a day for twelve weeks experienced a 60% reduction in the frequency of attacks, a reduction in the severity of the attacks they did have, and a reduction in the length of the attacks. Although the vascular theory of the cause of migraine is no longer supported, maintenance of the vascular system appears to at least reduce the likelihood of attacks.
The effect of butterbur on asthma and other allergic reactions is also well documented. This again is due to its anti-spasmodic properties and inhibitory effect on the inflammatory immune response through the inhibition of leukotriene synthesis and the consequent positive effect on the metabolism of prostaglandin. Prostaglandins also constrict vascular smooth muscle cells, regulate the mediation of the inflammatory response and constrict general smooth muscle cells. All of these can lead a to a variety of disorders cause by smooth muscle spasms in additional to urinary incontinence, such as menstrual cramps, liver and gastrointestinal disorders and asthmatic conditions.
In one study of allergic rhinitis, administration of butterbur extract appeared to result in a reduction in the histamine and leukotriene content of nasal fluids and no difference was noticed between this treatment and histamine treatment. This was a useful study because histamines causes drowsiness and butterbur can be used as a substitute for histamine without the sedative effect. A study in Germany in 1993 has shown that the stomach ulceration caused by the anti-inflammatory medications for arthritis was reduced by the administration of butterbur extract
Cetirizine is a commonly prescribed prescription treatment for allergic conditions, and studies comparing that with butterbur demonstrated them to be equally effecting in reducing the symptoms typical of allergic reactions such as sneezing, runny nose and nasal congestion. 50% of the patients in the group took each and there was no difference in results. Again it was explained by the petasin limiting the production of leukotriene and histamine, both of which are produced by the immune response and promote mucous secretions and inflammation. They also constrict Airways that can be serious to asthma sufferers
These studies are simply providing scientific evidence and explanations for the tradition use of this plant for such conditions. Butterbur has been used for centuries to treat such conditions all over Western Europe, and once again the use of traditional medicine has been supported by modern investigative techniques.
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Date:
April 03, 2008 12:43 PM
Boswellia is a tree that has a number of different species that have been used in Ayurvedic medicine. This is a form of Indian medicine that is used today by millions in India, and also in the neighboring Nepal and Sri Lanka. Its approximate translation is ‘Meaning of Life’, or could even be subtended to ‘Science of Life’, and is more a system of health care than the treatment of specific conditions.
There are four species of Boswellia: Boswellia carteri, Boswellia frereana, Boswellia sacra and Boswellia serrata, and it is B.serrata that is predominantly used in Ayurvedic medicine to treat a number of conditions, including ulcers, rheumatoid arthritis, dysentery and asthma. It is not coincidence that most of these are inflammatory conditions, and even dysentery is a form of inflammatory colitis.
You might be more familiar with Boswellia by the fragrant resin that it produces: Frankincense. There are different grades of Frankincense according to the species and grade of Boswellia, and if you are using the resin for its aroma then that could be an important consideration. However, the active ingredient of Boswellia are the so called boswellic acids that are contained within the resin.
It has been used in the treatment of a number of inflammatory conditions including asthma. Many do not realize that asthma is an inflammatory response of the immune system to particulate irritants in the Airway such as cigarette smoke and other small particles. In this case the inflammation is caused by the histamine that is released by mast cells sent to the area of irritation by the immune system.
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Date:
April 03, 2008 12:43 PM
Inflammation occurs because of the reaction of your immune system to what it perceives as being the presence in your tissues of dangerous foreign particles. Your immune system generally reacts to particles. Typical particles are bacteria and viruses, pollen, smoke, your own body cells that are not doing what they should, moulds and fungi, and various other things that can circulate in your blood.
There are several reasons for the immune system being activated, some of them historical due to your body having an imprinted memory of previous bacteria and viruses that it has dealt with, and others the reaction to new invaders that it has never met before, and for which your immune system creates antibodies to destroy. Another is the recognition of abnormal body cells that have to be destroyed before they can proliferate, and yet another is when the immune system gets confused and itself damages your own tissues such as in rheumatoid arthritis.
Whatever the cause, inflammation is a common result of the immune system going to work, and can be extremely painful. It can cause damage to our own joints, vascular system and major organs, although treatment of the inflammation does not reduce the effectiveness of the immune response. You can safely treat the inflammation with anti-inflammatories and painkillers without the condition getting worse.
Common physical manifestations of inflammation are the swollen and painful joints of rheumatoid arthritis (osteoarthritis is not an immune response), the swelling in the Airway of asthma, the spots and swellings of measles and chickenpox, the lesions of psoriasis and the swelling and pain of abrasions and cuts that have gone ‘septic’ or ‘poisoned’. The latter two are simply examples of the effect of phagocytes and leucocytes on bacterial infection – the white blood cells and their cohorts!
The reason that inflammation causes pain is that it affects nerve endings, and causes pressure against the damaged tissues that initiated the immune response. Although regular painkillers can control the pain of inflammation to an extent, they are generally not the ideal treatment. Herbal treatments are not necessarily always the ideal treatments either, but boswellia is one herb that has been proved to be effective in reducing the pain of inflammation.
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Date:
February 11, 2008 03:48 PM
Quercetin is one of the more powerful of the body’s antioxidants, and it can also be used to reduce the rate of histamine release by the body normally initiated by contact with an allergenic substance (for which your immune system has designed an antigen). We shall examine the biochemical mechanism which this is achieved, but first let’s have a closer look at quercetin and what it actually is.
Quercetin is what is known as a phytochemical, which is simply the scientific name for a chemical that is naturally produced by plants. Other phytochemicals include vitamin C and omega 3 fatty acids, so the term is very broad ranging for any substance that is produced by plants. It is commonly known as a flavanol, one of a family of compounds known as flavonoids that give color to plants.
It is a very active flavonoid, with very powerful antioxidant properties, in addition to acting as an anti-histamine and anti-inflammatory. Histamine is an amine released as part of the body’s immune response to allergenics, and quercetin inhibits its manufacture and release. This amine is an irritant and can itself cause inflammation and the other symptoms associated with allergies such as runny and itchy eyes, a stuffy nose, sneezing and itchy spots. Quercetin can be used to alleviate these symptoms by blocking the manufacture in the body of the histamine that causes them.
It demonstrates other anti-inflammatory properties such as alleviating the symptoms of arthritis, and also helps to destroy free radicals in the body through its strong antioxidant properties, but before we discuss how it does this we shall have a closer look at the mechanisms used in its effect in inhibiting histamine.
Calmodulin is a protein that is used to transport calcium ions, Ca++, across the membranes of certain cells in the body, and by doing so it helps to mediate a number of biochemical processes within the body, among them the immune response and inflammation. It should not be thought these are always unwelcome responses: on the contrary, they are the body’s way of reacting to foreign bodies and preventing more serious conditions from developing.
However, there are instances where the body can become sensitized to certain substances and overreact to their presence leading to conditions such as hay fever or, considerably more serious, asthma. These are just two of the undesirable manifestations of the human immune system that we would be better without. What quercetin does is to prevent calmodulin from properly binding to certain enzymic proteins and so suppress the effect of these proteins. Among these are the enzymes that control the secretion of histamine from mast cells.
Mast cells are found mainly in areas prone to injury and at the interface between internal tissues and outside world, such as the nose, mouth, lungs, eyes, blood vessels and feet. They contain granules rich in histamine that degranulate and released the histamine when the immune system detects foreign bodies such as pollen grains and dust mites, especially when the body has created antigens against them.
Quercetin suppresses the release of histamine from the granules in the mast cells by preventing the degranulation. The release of the histamine is not completely halted, but its effects are reduced and quercetin is used in the treatment of asthma where it is believed to help reduce the symptoms by reducing histamine-induced swelling in the Airways.
A similar application of this flavonoid is in reducing the inflammatory response to arthritis, the main cause of the swelling of this painful condition. Your skin can also be affected by inflammation that is partially controllable by quercetin. Collagen and fibronectin biosynthesis is increased that help to maintain not only healthy joints, but also to speed up the healing of wounds and repair damaged nerves. It is also believed that quercetin can hold back the effects of aging on the skin, and slow down the formation of wrinkles.
There are other applications of this versatile flavanol, including its effect on acute prostatitis where it reduces oxidative stress and the accompanying inflammation of the prostate gland. In fact, it is believed to have positive effect on many conditions caused by free radical oxidation and excessive reaction by the immune system causing inflammation. Apart from the allergies and arthritis previously referred to, quercetin is believed to have been effectively used in the treatment of gout, macular degeneration and heart disease, and it can also help to prevent the oxidation of low density lipoproteins (LDL) responsible for transporting cholesterol to where it is needed to repair major blood vessels.
When these lipoproteins become oxidized by free radicals then the cholesterol associated with them tends to be excessively deposited in the arteries it is meant to be repairing, and lead to atherosclerosis. This condition can lead to heart failure or to strokes if the blood vessels are in the brain.
Studies have indicated that the flavonoid might help to prevent certain cancers by preventing the nutrition of some types of cancerous cells, effectively killing them. Due to its phytoestrogen properties, quercetin can be used to bind to the sites in cancerous cells that are receptive to estrogen and so prevent their growth. Many types of cancerous cells need estrogen for their growth and proliferation, and phytoestrogens mimic the effect of this hormone. However, these are laboratory studies, and more work is required.
More certain is the effect of quercetin on heart disease due largely to the aforementioned control of cholesterol deposition in your arteries, but also through its ability to strengthen the capillaries. However, when all things are considered, it is in the properties of this non-allergenic bioflavonoid to fight histamine release that it finds it’s most popular and effective use.
So what is the best way to take quercetin? Like most bioflavonoids, it is available naturally in the majority of plant foods. Particularly rich sources are broccoli, red onions, red apple skins, black tea, red wine, red and purple berries and almost all dark green leafy vegetables.
However, the name of the game these days is to take measured doses, and while you should continue to eat these foods, you can also receive controlled doses by use of supplements. From 200 to 500 milligrams thrice daily is a good average dose, depending on the severity of your immune reaction or allergy. Bromelain is believed to improve its absorption in the gut, and quercetin is frequently provided with bromelain, which itself is also a good treatment for allergies and excessive response of your immune system to irritation.
Bromelain is an enzyme, generally extracted from pineapple, and treatments higher than the above doses of quercetin with or without bromelain are available online, although like any natural remedy you should inform your own physician of the dosage you are taking.
There is no better non-allergenic bioflavonoid to fight histamine and its potentially unpleasant effects on your body than quercetin.
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Date:
June 14, 2006 09:40 AM
Side effects:
Advil – rash; ringing in the ears; headaches; dizziness; drowsiness; abdominal pain; nausea; diarrhea; constipation; heartburn; ulceration of the stomach and intestine; bleeding ulcers; black, tarry stools; weakness; orthostatic hypertension; reduced flow of blood to the kidneys; impaired function of the kidneys; congestive heart failure; asthma; disturbances of the gut; nausea; vomiting; diarrhea; indigestion; abdominal pain; bleeding of the stomach and intestine; perforation of the stomach and intestine; swelling of the lips, tongue and throat (angioedema); narrowing of the Airways (bronchospasm); fluid retention; hearing disturbances; decreased number of platelets in the blood (thrombocytopenia).
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Date:
December 07, 2005 05:43 PM
ls.com/proprietary/pdf/VitaberryBrochure.pdf g Kaplan M., Hayek T. , Raz A., Coleman R. and Aviram M. Pomegranate juice supplementation to apolipoprotein E deficient mice with extensive atherosclerosis reduces macrophages lipid peroxidation, cellular cholesterol accumulation and development of atherosclerosis. J. Nutr. 131: 2082-2089 (2001) Lars O Dragsted et. al., The 6-a-day study:effects if fruit and vegetables on markers of oxidative stress and antioxidative defense in healthy nonsmokers. American Journal of Clinical Nutrition, Vol. 79, No. 6, 1060-1072, June 2004 Fuhrman B. and Aviram M. Polyphenols and flavaonoids protects LDL against atherogenic modifications.In: Handbook of Antioxidants Biochemical, Nutritional and Clinical Aspects, 2nd Edition. Cadenas E & Packer L (Eds.) Marcel Dekker, NY(Pub.). 16:303-336 (2001) Wood, Jacqueline, et al. Antioxidant activity of procyanidin-containing plant extracts at different pHs. Food Chemistry 77 (2002) 155-161 Aviram M. Pomegranate juice as a major source for polyphenolic flavonoids and it is most potent antioxidant against LDL oxidation and atherosclerosis. Free Radical Research 36 (Supplement 1): 71-72 (2002) Jennifer Schraag, Antioxidants: Nature’s Way of Balancing Life. HSR Health Supplement Retailer, Vol. 11, No. 2, 24-27, February 2005 com/news/printNewsBis.asp?id=58665 com/news/printNewsBis.asp?id=58697
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Date:
July 13, 2005 09:24 AM
Relaxation, Music Reduce Post-Op Pain. New research has found that relaxation and music, separately or together, significantly reduce patients' pain following major abdominal surgery. The study, published in the May issue of the journal Pain, found that these methods reduce pain more than pain medication alone. Led by Marion Good, PhD, RN, of Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, Ohio, the study is supported by the National Institute of Nursing Research (NINR), at the National Institutes of Health. "This is important news for the millions of Americans who undergo surgery and experience postoperative pain each year," said Dr. Patricia A. Grady, director of the NINR.
"Better pain management can reduce hospital stays and speed recovery, ultimately improving patients' quality of life." Dr. Good and her research team studied three groups of patients undergoing abdominal surgery. In addition to the usual pain medication, one group used a jaw relaxation technique, another group listened to music, and a third group received a combination of relaxation and music.
Findings revealed that, after surgery, the three treatment groups had significantly less pain than the control group, which received only pain medication. "Both medication and self-care methods which involve patient participation are needed for relief," said Dr. Good.
"These relaxation and music self-care methods provide more complete relief without the undesired side effects of some pain medications." The findings have important implications for the 23 million people who undergo surgery and experience postoperative pain annually in the United States. Pain can hamper recovery by heightening the body's response to the stress of surgery and increasing tissue breakdown, coagulation and fluid retention. Pain also interferes with appetite and sleep and can lead to complications that prolong hospitalization.
Dr. Good and her research staff worked with 500 patients aged 18-70, who were undergoing gynecological, gastrointestinal, exploratory or urinary surgery. Prior to surgery, those in the music, relaxation or combination groups practiced the techniques. The relaxation technique consisted of letting the lower jaw drop slightly, softening the lips, resting the tongue in the bottom of the mouth, and breathing slowly and rhythmically with a three-rhythm pattern of inhale, exhale and rest. Patients in the music group chose one of five kinds of soothing music--harp, piano, synthesizer, orchestral or slow jazz.
On the first and second days after surgery, all patients received morphine or Demerol for pain relief by pressing a button connected to their intravenous patient controlled analgesia pumps. The groups receiving the additional intervention used earphones to listen to music and relaxation tapes during walking and rest, while the control group did not. The research team measured the patients' pain before and after 15 minutes of bed rest and four times during walking to see if the sensation and distress of pain changed.
Dr. Good found that during these two days postsurgery the three treatment groups had significantly less pain than the control group during both walking and rest. "Patients can take more control of their postoperative pain using these self-care methods," says Dr. Good. "Nurses and physicians preparing patients for surgery and caring for them afterwards should encourage patients to use relaxation and music to enhance the effectiveness of pain medication and hasten recovery."
Dr. Good's findings have implications for future research into the effectiveness of self-care methods on other types of pain, including chronic pain, cancer pain, and pain of the critically ill.
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Vitamin D Lack Linked to Hip Fracture. Vitamin D deficiency in post-menopausal women is associated with increased risk of hip fracture, according to investigators at Brigham and Women's Hospital in Boston, Mass. In a group of women with osteoporosis hospitalized for hip fracture, 50 percent were found to have a previously undetected vitamin D deficiency. In the control group, women who had not suffered a hip fracture but who were hospitalized for an elective hip replacement, only a very small percentage had vitamin D deficiency, although one-fourth of those women also had osteoporosis. These findings were reported in the April 28, 1999, issue of the Journal of the American Medical Association.
The study, conducted by Meryl S. LeBoff, MD; Lynn Kohlmeier, MD; Shelley Hurwitz, PhD; Jennifer Franklin, BA; John Wright, MD; and Julie Glowacki, PhD; of the Endocrine Hypertension Division, Department of Internal Medicine, and Department of Orthopedic Surgery, Brigham and Women's Hospital, Boston, was supported by grants from the National Institute on Aging (NIA) and the National Center for Research Resources (NCRR. These investigators studied women admitted to either Brigham and Women's Hospital or the New England Baptist Hospital, both in Boston, between January 1995 and June 1998.
A group of 98 postmenopausal women who normally reside in their own homes were chosen for the study. Women with bone deterioration from other causes were excluded from the study.
There were 30 women with hip fractures caused by osteoporosis and 68 hospitalized for elective joint replacement. Of these 68, 17 women also had osteoporosis as determined by the World Health Organization bone density criteria. All the participants answered questions regarding their lifestyle, reproductive history, calcium in their diet, and physical activity.
Bone mineral density of the spine, hip, and total body were measured by dual X-ray absorptiometry (DXA) technique, as was body composition. Blood chemistry and urinary calcium levels were analyzed. The two groups of women with osteoporosis did not differ significantly in either time since menopause or bone density in the spine or hip. They did, however, differ in total bone density.
The women admitted for a hip fracture had fewer hours of exercise than the control group. Fifty percent of the women with hip fractures were deficient in vitamin D, 36.7 percent had elevated parathyroid hormone (PTH) levels (a hormone which can stimulate loss of calcium from bone), and 81.8 percent had calcium in their urine, suggesting inappropriate calcium loss. Blood levels of calcium were lower in the women with hip fractures than in either elective group.
These researchers propose that vitamin D supplementation at the time of fracture may speed up recovery and reduce risk of fracture in the future. Current Dietary Reference Intake Guidelines contain a daily recommendation of 400 IU of vitamin D for people aged 51 through 70 and 600 IU for those over age 70.
"We know that a calcium-rich diet and regular weight-bearing exercise can help prevent osteoporosis. This new research suggests that an adequate intake of vitamin D, which the body uses to help absorb calcium, may help women to reduce their risk of hip fracture, even when osteoporosis is present," observed Dr. Evan C. Hadley, NIA Associate Director for geriatrics research.
"Osteoporosis leads to more than 300,000 hip fractures each year, causing pain, frequent disability, and costly hospitalizations or long-term care. "Prevention of such fractures would greatly improve the quality of life for many older women and men, as well as significantly reduce medical costs." The bones in the body often undergo rebuilding. Some cells, osteoclasts, dissolve older parts of the bones. Then, bone-building cells known as osteoblasts create new bone using calcium and phosphorus.
As people age, if osteoporosis develops, more bone is dissolved than is rebuilt, and the bones weaken and become prone to fracture. Also in many older persons, levels of vitamin D in the blood are low because they eat less or spend less time in the sun, which stimulates the body's own production of vitamin D.
Experts do not understand fully the causes of osteoporosis. However, they do know that lack of estrogen which accompanies menopause, diets low in calcium, and lack of exercise contribute to the problem. Eighty percent of older Americans who face the possibility of pain and debilitation from an osteoporosis-related fracture are women. One out of every two women and one in eight men over the age of 50 will have such a fracture sometime in the future. These fractures usually occur in the hip, wrist, and spine.
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Sleep Apnea, Diabetes Link Found. Adults who suffer from obstructive sleep apnea are three times more likely to also have diabetes and more likely to suffer a stroke in the future, according to a new UCLA School of Dentistry/Department of Veterans Affairs study published today in the Journal of Oral and Maxillofacial Surgery. Sleep apnea, a serious condition marked by loud snoring, irregular breathing and interrupted oxygen intake, affects an estimated nine million Americans. The culprit? Carrying too many extra pounds.
"The blame falls squarely on excess weight gain," said Dr. Arthur H. Friedlander, associate professor of oral and maxillofacial surgery at the UCLA School of Dentistry and associate chief of staff at the Veterans Affairs Medical Center in Los Angeles. Surplus weight interferes with insulin's ability to propel sugars from digested food across the cell membrane, robbing the cells of needed carbohydrates. Diabetes results when glucose builds up in the bloodstream and can't be utilized by the body. Being overweight can also lead to obstructive sleep apnea, according to Friedlander.
"When people gain too much weight, fatty deposits build up along the throat and line the breathing passages," he explained. "The muscles in this region slacken during sleep, forcing the Airway to narrow and often close altogether." Reclining on one's back magnifies the situation. "When an overweight person lies down and goes to sleep," Friedlander said, "gravity shoves the fat in the neck backwards. This blocks the Airway and can bring breathing to a halt."
Friedlander tested the blood sugar of 54 randomly selected male veterans whom doctors had previously diagnosed with obstructive sleep apnea. He discovered that 17 of the 54 patients, or 31 percent, unknowingly suffered from adult-onset diabetes. Using the same sample, Friedlander also took panoramic X-rays of the men's necks and jaws. The X-rays indicated that 12 of the 54 patients, or 22 percent, revealed calcified plaques in the carotid artery leading to the brain.
These plaques block blood flow, significantly increasing patients' risk for stroke. Seven of the 12, or 58 percent, were also diagnosed with diabetes. In dramatic comparison, the 17 patients diagnosed with diabetes showed nearly twice the incidence of blockage. Seven of the 17 men, or 41 percent, had carotid plaques. Only five of the 54 patients who displayed plaques did not have also diabetes. If he conducted this study today, Friedlander notes, he would likely find a higher number of diabetic patients. After he completed the study in 1997, the American Diabetes Association lowered its definition for diabetes from 140 to 126 milligrams of sugar per deciliter of blood.
"This is the first time that science has uncovered a link between sleep apnea and diabetes," said Friedlander. "The data suggest that someone afflicted with both diabetes and sleep apnea is more likely to suffer a stroke in the future." "Persons going to the doctor for a sleep-apnea exam should request that their blood be screened for diabetes, especially if they are overweight," he cautioned. More than half of the individuals who develop diabetes as adults will need to modify their diet and take daily insulin in order to control the disease, he added.
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Stress, Surgery May Increase CA Tumors. Stress and surgery may increase the growth of cancerous tumors by suppressing natural killer cell activity, says a Johns Hopkins researcher.
Malignancies and viral infections are in part controlled by the immune system's natural killer (NK) cells, a sub-population of white blood cells that seek out and kill certain tumor and virally infected cells. In a study using animal models, natural killer cell activity was suppressed by physical stress or surgery, resulting in a significant increase in tumor development.
These findings suggest that protective measures should be considered to prevent metastasis for patients undergoing surgery to remove a cancerous tumor, according to Gayle Page, D.N.Sc., R.N., associate professor and Independence Foundation chair at the Johns Hopkins School of Nursing. "Human studies have already found a connection between the level of NK activity and susceptibility to several different types of cancer," says Page, an author of the study.
"We sought to determine the importance of stress-induced suppression of NK activity and thus learn the effects of stress and surgery on tumor development. "Many patients undergo surgery to remove cancerous tumors that have the potential to spread. If our findings in rats can be generalized to such clinical settings, then these circumstances could increase tumor growth during or shortly after surgery." The research was conducted at Ohio State University College of Nursing and the Department of Psychology at UCLA, where Page held previous positions, and at Tel Aviv University.
Results of the study are published in the March issue of the International Journal of Cancer. In laboratory studies, Page and her colleagues subjected rats to either abdominal surgery or physical stress, and then inoculated them with cancer cells. In the rats that had undergone surgery, the researchers observed a 200 to 500 percent increase in the incidence of lung tumor cells, an early indicator of metastasis, compared with rats that had not received surgery.
The experiment also showed that stress increased lung tumor incidence and significantly increased the mortality in the animals inoculated with cancer cells. "Our results show that, under specific circumstances, resistance to tumor development is compromised by physical stress and surgical intervention," says Page.
"Because surgical procedures are life-saving and cannot be withheld, protective measures should be considered that will prevent suppression of the natural killer cell activity and additional tumor development. "Researchers do not yet know how to prevent surgery-induced immune suppression, but early animal studies have shown increased use of analgesia reduces the risk."
The study was funded by the National Institutes of Health, and the Chief Scientist of the Israeli Ministry of Health. Lead author was Shamgar Ben-Eliyahu, Ph.D., and other authors were Raz Yirmiya, Ph.D., and Guy Shakhar.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=599)
Date:
June 16, 2005 10:57 AM
Bromelain Sinus Ease™
Nature's Life Sinus Products: Sinus cavities are lined with delicate mucous membranes, which act as filters for your respiratory system. Normal sinuse tissues are pink and healthy. For many people, when their sinuses come in contact with allergens, pollutants or harmful micro-organisms, histamines are released as a protective measure by the immune system. Sinuses naturally respond by becoming irritated, red, and inflamed with these healing histamines. This process, called the natural inflammatory response, helps to neutralize and remove the irritants in sinuses cavities. Sometimes, however, the immune system continues to flood the sinuses even after the irritants are removed. Bromelain Sinus Ease™ contains three ingredients that have been shown to enhance the body’s ability to reduce this natural inflammatory response and help clear up sinuses.* Bromelain Bromelain is a group of protein-digesting enzymes extracted from pineapples (Ananassa sativa). Bromelain breaks down fibrin—a key component of the body’s natural inflammatory response to allergens and other foreign stimuli.* Bromelain also appears to inhibit the natural formation of prostaglandins (hormone-like substances) that trigger the natural inflammatory response.*1 It makes mucus less thick,2 allowing the mucus to drain more easily.* Human trials have shown that by breaking down and helping to remove fibrin, bromelain reduces the discomfort of irritated tissues.*3 Double-blinded trials in patients with irritated sinuses show that the natural inflammatory response is reduced more effectively by concentrated bromelain than by placebo.*4 ,5 ,6 ,7 In all cases, a majority of people responded well to bromelain supplements.* Bromelain has also helped reduce the duration of the natural inflammatory response after nasal procedures by over 70% in a controlled trial.*8 The recommended daily amount of Nature’s Life Sinus Ease™ utilizes 1,200 mg a very high potency bromelain enzyme which has an activity of 2,880 GDU (Gelatin Digestive Units), or 4,320 MCU (Milk Clotting Units) per serving. Vitamin C also helps reduce histamine release.*9 Some studies have reported that vitamin C is useful in reducing the natural inflammatory response in nasal passages.*10, 11, 12 The effectiveness of vitamin C in reducing histamine release is still debated, however, because a controlled trial was unable to show consistent effects.*13 Doses up to 2 grams per day have been used by researchers. It may be difficult to show these effects in research trials because vitamin C appears to help only some people without affecting others.*14 Studies, however, clearly show that vitamin C supplementation can lower elevated blood levels of histamines.*15, 16 Nature’s Life adds naturally-buffered vitamin C to Sinus Ease due to its safety, immune-supporting effects and potential efficacy to reduce histamine release.* Quercetin is a bioflavonoid found in many natural foods including citrus fruits, onions, apples, tea and lettuce. As with bromelain, quercetin helps reduce the natural inflammatory response by inhibiting the natural formation of the pro-inflammatory agents, prostaglandins and leukotrienes (white blood cells).*17,18 Quercetin also helps lessen the natural inflammatory response for children with sensitivities to inhalants.*19 Additionally, quercetin may help reduce the effects of harmful micro-organisms *20 Bioflavonoids at doses of 1,200 mg per day have reduced the natural inflammatory response in human studies in combination with 1,200 mg vitamin C,21 an outcome confirmed in double-blinded research using 600 mg/day of bioflavonoids and 450 mg/day of vitamin C.*22 Substances which inhibit the natural inflammatory response rarely target just one part of the body.* While quercetin has yet to be tested in reducing the natural inflammatory response in sinuses specifically, doctors of natural medicine frequently use it for that purpose because of its proven ability to lessen the natural inflammatory response elsewhere in the body.* Nature’s Life has combined these powerful phytonutrients to make Sinus Ease™. High potency Bromelain, Quercetin and vitamin C work to inhibit the natural pro-inflammatory response and encourage adequate sinus drainage.* No safety concerns have been identified with any of these ingredients.23, 24 It is recommended to take the three capsules per day between meals. Since bromelain is a proteolytic enzyme, if taken with a meal it will act on the protein in the food rather than the natural pro-inflammatory fibrin, so remember to take it between meals.* Enjoy the winter season and find relief from allergens throughout the year! Nature’s Life Sinus Ease™ can help. References: Martin GJ. Bromelain pineapple proteases with anti-edema activity. Exper Med Surg 1962;20:228-48. Blonstein JL. Control of swelling in boxing injuries. Practitioner 1969;203:206. Seltzer AP. Adjunctive use of bromelains in sinusitis: a controlled study. EENT Monthly 1967;46:1281-8. Taub SJ. The use of Ananase in sinusitis—a study of 60 patients. EENT Monthly 1966;45:96-8. Ryan RE. A double-blind clinical evaluation of bromelains in the treatment of acute sinusitis. Headache 1967;7:13-7. Taub SJ. The use of bromelains in sinusitis: a double-blind clinical evaluation. EENT Monthly 1967;46:361-5. Seltzer AP. Minimizing post-operative edema and ecchymoses by the use of an oral enzyme preparation (bromelain). EENT Monthly 1962;41:813-7. Johnson CS, Martin LJ, Cai X. Antihistamine effect of supplemental ascorbic acid and neutrophil chemotaxis. J Am Coll Nutr 1992;11:172-6. Zuskin E, Lewis AJ, Bouhuys A. Inhibition of histamine-induced Airways constriction by ascorbic acid. J Allergy Clin Immunol 1973;51:218. Ruskin SL. High dose vitamin C in allergy. Am J Dig Dis 1945;12:281. Holmes HN. Hay fever and vitamin C. Science 1942;96;497. Fortner BR, Danziger RE, Rabinowitz PS, Nelson HS. The effect of ascorbic acid on cutaneous and nasal response to histamine and allergen. J Allergy Clin Immunol 1982;69:484-8. Bai TR, Martin JG. Effects of indomethacin and ascorbic acid on histamine induced bronchoconstriction in normal subjects. NZ Med J 1986;99:163 [abstr]. Holmes H, Alexander W. Hay Fever and Vitamin C. Science 1942;96:497-99. Johnston CS, Martin LJ, Xi C. Antihistamine Effect of Supplemental Ascorbic Acid and Neutrophil Chemotaxis. J Am Coll Nutr 1992;11:172-6. Middleton E, Drzewieki G. Naturally occurring flavonoids and human basophil histamine release. Arch Allergy Applied Immunol 1985;77:155-7. Welton AF, Tobias LD, Fiedler-Nagy C, et al. Effect of flavonoids on arachidonic acid metabolism. Prog Clin BiolRes 1986;213:231-42 Balabokin II, Gordeeva GF, Fuseva ED, et al. Use of vitamins in allergic illnesses in children. Vopr Med Khim (Russia) 1992;38:36-40. Ohnishi E, Bannai H. Quercetin potentiates TNF-induced antiviral activity. Antiviral Res 1993;22:327-31. Miller MJ. Injuries to athletes. Med Times 1960;88:313-6. Cragin RB. The use of bioflavonoids in the prevention and treatment of athletic injuries. Med Times 1962;529-32. Taussig SJ, Yokoyama MM, Chinen N, et al. Bromelain: A proteolytic enzyme and its clinical application. Hiroshima J Med Sci 1975;24:185-193. Hertog MGL, Feskens EJM, Holman PCH, et al. Dietary flavonoids and cancer risk in the Zutphen elderly study. Nutr Cancer 1994;22:175-84. |