Search Term: " Environmens "
High-Fiber Diet Found Beneficial To Cancer Patients
April 22, 2019 04:35 PM
A study recently unveiled by its researchers at the American Association for Cancer Research's news conference shows that melanoma patients undergoing PD-1 blockade immune therapy had improved chances of reducing or shrinking tumors by eating a diet high in fiber along with their treatment. 46 patients out of the study's 113 showed improved response to the immune therapy, due to improved beneficial microbes in their stomachs. The researchers are planning a full presentation at the Cancer Research Association's annual meeting on April 2nd.
"Patients who had a high-fiber diet were found five times likely to reduce the growth or shrink tumors while taking an immune therapy."
Read more: https://www.medicaldaily.com/high-fiber-diet-found-beneficial-cancer-patients-430607
Gut microbes can fight parasites: Probiotics may reduce infections, and severity of infections, in developing countries
June 08, 2018 09:16 AM
Parasites are a more common problem in some parts of the world, where soil quality is particularly conducive to their survival and growth. Unfortunately, for individuals that get infected with these parasites, it's becoming harder to get rid of them, as successive strains become more resistant to drugs.
Fortunately, new research is discovering that keeping parasites at bay and destroying those already present may have more to do with the environment of the gut. Individuals from villages in Indonesia and Liberia were the data pool used to find guts harboring parasites as well as those free of them. It was found that some bacteria were actually assistive of the parasites, while others made it hard on them. Since inflammation is the way that the gut generally fights off parasitic invasion, those bacteria that are anti-inflammatory are not useful in ridding the body, although those that aid in producing an inhospitable environment are. It may be that a eating a great deal more fermented foods could be a key, as such foods encourage the production of friendly and useful bacteria.
"Your ability to fight off parasitic worms may be aided by your gut microbiota."
Read more: https://www.naturalnews.com/2018-06-05-gut-microbes-can-fight-parasites-probiotics-may-reduce-infections-and-severity-of-infections-in-developing-countries.html
Are gut microbes really a panacea, or just overhyped?
September 22, 2017 09:14 AM
Gut microbes and their role in physical as well as mental health has received a lot of attention in the past few years. Researchers are claiming that some day probiotic medicines can be taken to combat disease, both mental and physical. his is not just hype. Serious research is being done to learn how these microbes work on the human body with the hopes of creating probiotic like medications someday. Read here about these recent research advances.
"The gut microbiome does indeed show huge potential, but the research is still in its infancy, and many of the big questions remain unanswered."
Read more: https://www.theguardian.com/commentisfree/2017/sep/07/gut-microbes-panacea-brain-probiotic
Discover why Peppermint is the most powerful herb, ideal for cleansing the liver
September 20, 2017 12:14 PM
Peppermint is the most powerful herb, and it is ideal for cleansing the liver too. When we glance at it, peppermint looks like a mint plant, but this amazing plant with bright leaves is called peppermint and it has many different health benefits. Peppermint is easily adaptable to the environment and can live pretty much anywhere. It can be fun to grow it on your own. One of the main things that peppermint does is clean and purify your liver.https://www.youtube.com/watch?v=zKnThMRaYZ0&rel=0
"One of the main functions of peppermint is to clean and purify, and the first organ benefited is the liver."
Mice fed tryptophan develop immune cells that foster a tolerant gut
August 13, 2017 09:14 AM
Tryptophan is a fundamental building block of protein. A study was conducted on genetically identical mice that were separated and raised in different environments, which led to the finding that environmental factors were a high contributor in regards to developing an immunity to irritable bowel disease. Bacteria highly affects the immune system because the mice that were raised in sterile conditions grew the immune cells. Doctor Luisa Cervantes-Barragan conducted the study. Tryptophan is common in both mouse and the human balanced food diet.
"People have the same tolerance-promoting cells as mice, and most of us shelter L. reuteri in our gastrointestinal tracts."
Read more: https://medicalxpress.com/news/2017-08-mice-fed-tryptophan-immune-cells.html
How to Get Rid of Acne, Stains and Pimple Marks Naturally
July 27, 2017 05:14 AM
Our appearance is crucial to making positive first impressions, so it makes sense to take care of our face. However, problems like acne, unhealthy environments, and even poor diets can leave unwanted marks on a person's face. Because of this, safe, natural, and cost effective remedies to this problem are treasured. There exists one recipe to alleviate this problem, involving common ingredients that could be found in most homes; water, apple cider, lemon, baking soda, and honey. Together, these ingredients can form a mixture that, when properly applied, can help restore appearance to one's face by removing blemishes and pimples. However, it is important to check for allergies before applying the mixture, and you must avoid sunbathing the next day.https://www.youtube.com/watch?v=eFt0AvmNWRQ&rel=0
"Many young people suffer from low self-esteem due to blemishes and acne."
Environment's Effect on Health
April 27, 2017 10:44 PM
The environment can take a toll on a persons health. It can disturb a persons well being and cause health concerns. The World Health Organization defines environment, as it relates to health, as "all the physical, chemical, and biological factors external to a person and all the related behaviors." The pollutants in the environment can contribute to heart disease and stroke. Some of the most dangerous pollutants are carbon monoxide, nitrates, sulfur dioxide, lead, and secondhand tobacco smoke. Things that you can do to limit your output of pollutants would be to walk to places instead of driving when possible, not buy bottled water and instead use a reusable one. You could also use fewer chemicals in household cleaning.
Read more: Environment's Effect on Health
These raised bed gardening tricks beat traditional gardening every time
March 29, 2017 11:59 AM
Raised bed gardening methods involves preparing crops in a variety of ways using elevated garden beds. Benefits of raised garden beds include better drainage as well as better retention of moist soil. This makes raised beds particularly effective in rainy environments. In addition to better drainage, raised beds also provide better aeration. Raised beds allow effective use of the loose soil such as air circulation and nitrogen being converted to useful minerals. Other benefits include better weed control, pest control, and improved mobility.
Read more: These raised bed gardening tricks beat traditional gardening every time
Fake weed: Why does government marijuana look so weird?
March 27, 2017 08:59 AM
The government, yet again, is trying to control/discourage research and development of products related to marijuana. Outlined here is how the only products available for research studies are outdated, ineffective, and poor quality marijuana plants. Most plants that are used are grown in outdated environments and conditions. In states where the plant is legal, it can't be used for research purposes. The product must be the sub-standard, government issued plants. People who could benefit from this research, should pay attention to, and follow-up on this report.
"Photographs of the government marijuana samples received by Sisley show a substance that bears almost no resemblance to commercial marijuana."
Read more: http://www.naturalnews.com/2017-03-23-fake-weed-why-does-government-marijuana-look-so-weird.html
5 Sure Fire Ways to Know if You Have Hashimoto’s
December 22, 2016 10:59 AM
Hashimoto’s disease is a hypothyroid disorder that is caused by an immune attack on your thyroid. This leads to a generally fatigued and weak feeling that persists longer than expected. It can also affect the health of your hair, your weight, and how you respond to cold environments. So, if you have been feeling rundown for a while and just generally down in the dumps with any of the other above symptoms, it may be time to talk to your doctor to get tested.
"Hashimoto’s is the most common autoimmune thyroid disorder. For a variety of reasons, your immune system sets out to attack your thyroid gland. Over time, the thyroid gland is slowly destroyed"
Schools are filled with bacteria, causing crippling lung function in children
December 19, 2016 07:59 AM
Sure, when you send your kids to school you worry about a lot of things: Fitting in, bullying, learning but never did you think that you would have to worry about bacteria from mice and other rodents. Researchers have shown that bacteria in school has caused an increase in asthma in school age kids. This is increasing at such an alarming rate that it finally caught the attention of health officials even though the effects have been happening for years.
"Some 284 children from 37 inner-city public schools located throughout the Northeastern United States were evaluated as part of the research."
If Inflammation is left un checked, it can turn into cancer
Chronic inflammation is caused by lifestyle choices:
Heart disease, diabetes, Alzheimer's, osteoporosis, depress, and cancer are all chronic inflammation diseases. Chronic inflammation can compromise your immune system, making it ineffective.
One simple herb can reduce inflammation, it is called curcumin. Not all Curcumin is alike, make sure yours has BCM-95.
why not take anti-inflammatory drugs?
Dental Benefits of Xylitol; Protect your teeth against decay.
October 07, 2014 08:34 PM
Supplements That Can Improve Focus
March 23, 2014 07:57 AM
A focused mind is one that is able to concentrate on a particular issue and think about it, discuss it or deal with it and pay special attention to that subject. This explains why people have different focus abilities as brought about by their varying environments and capabilities. Enhanced minds quickly grasp ideas as opposed to low minded ones. A determined mind therefore understands and interpret facts more readily in an effective way, and this is why it is important for individuals to to be focused at school. However, there are instances where learners have limited focus abilities, but this can be improved by use of focus supplements. The following are the supplements that can be used to boost an individual's focus levels.
Supplement that can help improve focus
Oregano Oil, Can It Help Me?
February 22, 2014 07:57 AM
Oregano oil contains powerful chemical substances that are responsible for its diverse medical applications. It contains a powerful combination of phytochemicals, flavonoids, and phenols that cannot be subdued by drug-resistant disease causing microorganisms. In addition, oregano oil is packed with considerable amounts of minerals, trace elements, and vitamins that make the body stronger and resistant to many diseases.
Benefits of oregano
Generally, oregano plant grows in harsh environments- conditions, which make it a good remedy for many stubborn health problems. To be precise, oregano plant grows in harsh environments in Portugal, Turkey, and Greece, where the soil is rich in minerals. The leaves of the oregano plant are crushed and distilled to get the oil, which is used for the following medical purposes.
Oregano oil is very effective in treating respiratory medical conditions such as pneumonia, colds, bronchitis, sinusitis, cold, and coughs. In most of the cases, antibiotics sold and bought in the drug stores are always not effective in getting rid of the viral cells that are mainly responsible for the majority of respiratory diseases. However, with oregano oil, it only takes a few drops to get rid of the viral cells from the respiratory tract.
Oregano oil is very important in the treatment of skin infections such as acne, ringworms, eczema, and skin rashes. The oil contains antiseptic chemicals that have the ability to get rid of all the bacterial microorganisms, which are responsible for various skin infections. In addition, the oil prevents the bacteria on the skin from multiplying and increasing in population.
Oregano oil is also used in the treatment of arthritis and herpes. The oil has an exceptional ability to fight and eliminate viral components in the body. As a result, it is used in fighting, killing, and eliminating Herpes Simplex Virus, which is responsible for herpes. Its anti-inflammatory qualities make it a good solution to arthritis and any other related problems.
What Causes Glycine Malabsorption?
September 09, 2011 04:33 PM
Glycine is known to be the smallest amino acid in the human body and it is present in both water and fatty based environments. This has been one of the most researched amino acid to date and most results indicate that it has an important role in normal bodily function maintenance. It has the ability to supply collagen to the human body as one of its main functions. Studies have also found that glycine is also used to build both fibrous and muscle tissues which is why it has been used as a treatment for degenerative diseases. Aside from this main function glycine also plays such a wide range of roles in other bodily functions as it is playing a part in numerous system processes, from aiding in blood sugar conversion to affecting the nervous system it truly has made itself essential to the body.
That is why any malabsorption or lowering of glycine levels in the body can cause harmful and detrimental effects in any person’s well being. Furthermore, it also has been proven in many studies that glycine has an antioxidant effect which aids in the body’s war against free radicals. In recent years there has been an increase in the popularity of glycine, so much so that some food products have been fortified with it just to up their value in the consumer’s eyes as they know that America is getting more and more health conscious as the days go by. Since the body is capable of producing this substance it is considered as a non essential amino acid. It is seldom that the body will totally run out of this substance however lowered levels due to various reasons are absolutely possible. Which brings me back to how is malabsorption of Glycine caused.
Glucose and Galactose Presence
Studies have been done to show how glycine absorption can be impaired and what they were able to find out is that there is a competition between forms of sugar like glucose and galactose and glycine for intestinal transport. The results show that there was a decrease in absorption of both substances whenever the other is present. For glycine the drop in absorption was over 50 percent and for the sugars there was also significant decrease in uptake and absorption. What this entails in the real world is that regions with high carbohydrate diets maybe affected and may have cases of Glycine absorption impairment more so than other regions with lower carbohydrate diets however this is not taking into account any gastrointestinal damage that may also affect glycine absorption.
In cases that a person has gone through surgery they may suffer from Glycine malabsorption, this is not something to be that worried about as anesthesia is not consistently present in the body and realistically very few individuals have surgery often and surgery that requires anesthesia I might add. Studies have shown that local anesthesia is the one that is more harmful to glycine absorption compared to general anesthesia.
If you have a glycine malabsorption problem, supplementing with the amino acid will help restore these low levels. Grab some glycine and feel the difference it can make in your energy.
How Does Tart Cherry Work To Fight gout and Inflammation?
May 25, 2011 12:46 PM
Health Benefits Of Tart Cherry
Tart cherry may be the newest addition to the growing list of superfruits. This species of sour cherries have been cultivated for centuries, but only recently has research started to uncover its medicinal potential. It is believed to contain a larger number of phenolics and anthocyanins than its sweet counterparts. Plus, it has been linked to more studies in the past few years.
Prunus cerasus are species of cherries native to Europe and parts of Asia. Tart cherries have less than 10 varieties cultivated around the world, but they have steadily grown in popularity. There are two major cultivars: the bright red amarelle and the darker morello. Among the popular cultivars are Montmorency, Balaton, and Griotte de Kleparow.
Counteracts Pain Chemicals
Anthocyanins have long been associated with the alleviation of joint pains and related symptoms, and tart cherry are among the best sources of these organic compounds. Anthocyanins are actually pigments that give fruits such as apples and cherries their red coloration. As a general rule, fullness of color is directly proportional to the anthocyanin content of fruits. Cancer research on anthocyanins is considered unrivaled due to the availability and reliability of documented data. The anthocyanins found in tart cherries counteract the inflammatory mediators that initiate tumorigenesis, which are the same chemicals responsible for sensitizing joints to pain.
Promotes Purine Metabolism
Gout ensues when purine metabolites in the form of uric acid crystallizes and in the process triggers local inflammatory responses. High levels of uric acid in the blood may form into urate crystals anywhere, but often precipitate in the joints of the lower extremities. The big toe is particularly vulnerable to gout, but it may also manifest in the form of joint pains and kidney stones. Unfortunately, human beings lack a functional enzyme that breaks down uric acid and re-balance uric acid levels. This is when tart cherries come to the rescue. They contain phytochemicals that regulate purine metabolites and promote the excretion of uric acid.
Accelerates Muscle Recovery
It is a common belief in the nutraceutical industry that tart cherries are one of the best sources of antioxidants. Free radicals are natural by-products of cellular respiration, and they become so abundant during workout that the muscles begin to feel sore. It takes a longer time to recover from radical damage when the antioxidant defense of cells is compromised. The antioxidant profile of tart cherries enables the skeletal muscles to recuperate fast after intense physical exertion.
Improves Sleep Disorders
Tart cherries have been commercially touted to cure insomnia. While this remains to be proven, tart cherries are in fact excellent sources of melatonin, the primary hormone responsible for inducing sleep in response to dark environments. Sleep disorders may result from a variety of factors, including stress, and sudden lifestyle changes may interfere with the chemical reactions that govern our biological clock. Tart cherries provide a ready source of melatonin, which normalizes circadian rhythm and enables the brain to relax.
Fight back against gout and inflammation pain with Tart Cherry.
Potassium Iodide (KI) Fact Sheet: What You Should Know
March 28, 2011 04:53 PM
Facts About Potassium Iodide (KI)
1. Potassium iodide, or KI is an over-the-counter drug and an additive to food, including dietary supplements.
2. Potassium iodide can be found naturally in many types of seaweed - particularly those grown in iodine rich environments, such as brown algae, kelp and bladderwrack - as well as in some salt water fish.
3. Commercial table salt, specifically iodized salt, and dairy products such as low fat yogurt, milk, and some cheeses also can be significant sources of the recommended allowance (RDA) of iodine.
4. Additionally, dietary supplements can contain seaweed or other potassium iodide sources, and should be calculated in ones daily intake.
5. The amount of potassium iodide in dietary supplements for nutritional and thyroid support is more likely to be measured in micrograms (a microgram is 1/1000 of a milligram).
Radiation and Potassium Iodide (KL)
1. The recommended adult dosage of KI in cases of radiation exposure is 130 milligrams, far higher than the normal nutritional need of 0.15 milligrams, or 150 micrograms, per day for an adult (RDA recommendation).
2. The consequences of iodine poisoning from overdosing can be extremely serious, and include nausea, seizures, vomiting, and shock.
3. KI protects only the thyroid gland against radiation exposure for approximately 24 hours per dose. KI should be taken within three hours of exposure.
For More Information:
1. U.S. Food and Drug Administration (FDA), Radiation Safety: www.fda.gov
2. Centers for Disease Control and Prevention (CDC), Radiation: www.cdc.gov
**Please note: you should only take KI on the advice of emergency management officials, public health officials, or your doctor – but never as a preventative measure in the doses recommended for radiation treatment.
The Amino Acid Glycine Is A Component Of Collagen And Essential For Good Health?
March 23, 2011 03:45 PM
What Is The Amino Acid Glycine And How does it Work In the Body
Glycine is the smallest amino acid found in the human body. It is present not only in water-based environments but also in fatty tissues. Being one of the earliest amino acids to be discovered, it has been a subject of numerous studies in the last century. The abundance of data points to its indispensable role in maintaining the overall health of the body since it is quite ubiquitous at the cellular level.
Supplies Amino Acid Requirement of Proteins in Cells
It is a widely accepted fact that glycine is an amino acid necessitated for the production of proteins that the human body uses and accounts for more than 30 per cent of the protein group called collagen. Human cells in particular utilize glycine in manufacturing fibrous and muscle tissues, the reason why it has been in use in treatment of degenerative diseases. The total absence of glycine in the human body is impossible, given the role it plays in protein synthesis, but low levels of glycine can be harmful.
Converts into Glucose and Helps Regulate Blood Sugar
Glucogenic amino acids are a number of amino acids that can be converted into glucose. First on the list is glycine, which does not only aid against a sudden drop in blood sugar but also provides the body with enough glucose to support cellular functions. Feelings of weakness characteristic of fibromyalgia and chronic fatigue are often attributable to an impaired capacity to produce enough energy. The process of gluconeogenesis converts non-carbohydrate compounds into glucose as a response.
Displays Inhibitory and Excitatory Neuronal Activities
While GABA is the primary inhibitory neurotransmitter in human beings, glycine is also known to display inhibitory activities in the central nervous system. The spinal cord, brainstem, and the forebrain have all been identified to employ this amino acid in gylcinergic neurotransmission, which may be inhibitory or excitatory. It is postulated that glycine plays a major role in various mental disorders, and several studies concerning its psychoactive potential are well underway.
Scavenges Free Radicals and Reactive Oxygen Species
Although it is not considered an essential amino acid, which means the body produces quantities adequate to support physiological functions, depleting levels of glycine is not uncommon especially in individuals suffering from malnutrition and malabsorption. Glycine supplements have seen a surge in popularity in the latter half of the century as they are also known for their antioxidant activities. Enzymes responsible for antioxidant defenses necessitate glycine, which is an antioxidant in itself.
Supplementation of glycine has risen in the past few years especially when studies associating this amino acid to degenerative diseases have started to surface. A number of scientists believed that age-related and other degenerative diseases such as arthritis and osteoporosis may be classified as deficiency diseases in that these diseases can easily be prevented or reversed with diet modifications. The incorporation of glycine in food products has also been reported to contribute to the upkeep of protein complexes needed by joints, muscles, and other parts of the body.
How Does Cherry Fruit Extract Help with Gout?
March 07, 2011 04:39 PM
Cherry fruit extracts contain the micronutrients and phytochemicals found in cherries. They are available as supplements widely touted to display antioxidant and anti-inflammatory properties. Cherries, the fruits, are in fact very high in anthocyanins, which have a long association with the prevention of inflammation, even including the type that results in most known cardiovascular diseases. Also, research on anthocyanins in connection with its chemopreventative potential has yielded the most reliable public data. Individuals suffering from gout will definitely benefit from cherry fruit extracts as supported by an abundance of reports and anecdotal evidence concerning its efficacy.
Stabilizes Metabolism of Purine Nucleotides
The development of gout is greatly attributable to an anomaly in the metabolism processes involving purine nucleotides. A class of organic compounds classified as purines is necessary for life and present in many chemical reactions. They are a major component of ATP, the primary energy of cells, and several nucleotide bases of DNA and RNA are purines. The problem lies in its final metabolic product, uric acid, which at high levels condense into urate crystals that are deposited in tendons and ligaments, as is the case with gout and tophus. Cherry fruit extracts bring about twofold effects. First, they stabilize purine metabolites, notably uric acid, and, second, they facilitate the effective excretion of uric acid. If you consume a lot of foods high in purines such as animal products, especially beef, pork, and seafood, taking cherry fruit extracts will make sure that the uric acid they produce gets out of your system.
Affects Releases of Inflammatory Mediators
While high levels of uric acid is the causation of gout attacks, the painful inflammation that ensues is triggered by an entirely different group of endogenous compounds in the employ of the immune system. Eicosanoids have long been identified to precipitate pain not only during gout attacks, but in all inflammatory responses of the human body. These compounds are released locally by the cells around the joints containing urate deposits in an attempt to fight off the degenerative effects of uric acid on the surrounding tissues. They deal with the joints the same way they get rid of pathogens during infections, bringing on the redness, swelling, and pain characteristic of gout. A group of bioflavonoids called anthocyanins that are known to interfere with the releases of eicosanoids are abundant in cherries, and intake of cherry fruit extracts deliver these flavonoids into the region of pain.
Normalizes Acidic Digestive Environments
Cherries belong to the group of foods that are alkaline forming. With gout thriving in an acidic setting, it is just prudent to carefully reassess your diet and cut down on foods high in purines. Not surprisingly, your doctor may tell you to minimize consumptions of meat products especially if you suffer from recurrent gout attacks. Cherry fruit extracts rebalances the pH level of your gastrointestinal tract, and supplementation will keep your body in an alkaline state in the long run, protecting you not only against gout but also against the aging process.
If you suffer from gout or other uric acid buildup disease, give cherry fruit extract a try today!
Avage Nectar Facts
April 08, 2010 04:02 PM
First of all let me preface by saying thank you very much for contacting Madhava Honey with your concern. Madhava has been in business for over 36 years and one of our four fundamental core values is and always will be to provide the Highest Quality product that exceeds the industry standard. Our other three core values are providing a product with the highest respect to the environment and health of the consumer, supporting community development via living wages and sustainable development of local economies, and finally providing a fair guaranteed price for our suppliers. Thirty six years ago Madhava was founded on "sustainable" practices and we take negative misleading attacks on our products very seriously. Madhava will try to respond to all the issues in question along with providing a little bit of background information on the source of the attacks. Finally at Madhava we believe in full transparency and please do not hesitate to contact us directly if you feel any questions or concerns have not been addressed. Thank you very much.
A. What constitutes Madhava's Agave Nectar?
There are 3 main components of our Agave Nectar. It is naturally composed primarily of the simple sugars fructose, glucose (dextrose), and water. Madhava’s Agave is Certified Organic and is Genetically Modified Organism (GMO) Free.
B. How is Madhava's Agave Nectar produced?
The Agave plant is truly a remarkable plant! It grows in the harshest environments with little water and no upkeep is needed. It is naturally found in Western Mexico making it a non-evasive plant to the area regarding its growth and harvest. It requires no pesticides or fertilizers and is actually a cornerstone to its ecosystem. The Agave plant is truly a sustainably grown/harvested crop.
The Agave plant is grown for 6-8 years, then before turning to seed, it is then harvested by hand. Jimadores or Agave harvesters go to the selected fields and remove the "Pina" or heart of the Agave plant, by cutting off the long spiny "leaves" and unearthing it from the soil. It is all done by hand thus reducing the carbon footprint during harvesting. The Pinas are then loaded to a truck which takes them back to the harvesting facility.
There are two methods of making the Agave Nectar from the juice of the plant. One uses a natural non-GMO enzyme and the second uses thermal hydrolysis. Both processes achieve the same goal; which is to separate the naturally occurring Fructans, which are complex sugar molecules into their simple sugar components fructose and glucose.
The actual process of hydrolysis of agave, either thermal or enzymatic, is unlike the process of High Fructose Corn Syrup (HFCS), which creates fructose out of the glucose made from the milled starch of corn. Agave Nectar simply separates Fructans or Inulin, a complex naturally occurring sugar, into Fructose and Glucose.
C. Moderation vs. Overconsumption
It is certainly true that overconsumption of any one or a combination of sugars can have detrimental effects, but this is not in a vacuum, it involves lifestyles, other food choices and other conditions. Overconsumption of any food or beverage will have ramifications. Sweeteners are ingredients which are added to foods in relatively small quantity to make them more palatable. In others, sugars can make up a large portion of the caloric value. These foods are easy to identify and avoid as necessary. People do not consume sweeteners as a solitary food in mass quantity. They are just part of the choices people make and consumption can be controlled, each of us chooses what we eat and how much. There are no health issues with moderate consumption of sweeteners; every negative circulating is relative to the overall consumption of one's diet.
Protect The Liver with Glutathione And Cysteine
April 23, 2009 01:54 PM
The tripeptide L-glutathione is synthesized in the body from L. glutamic acid, L-cysteine and glycine, a reaction that can occur in any cell of the body although it is essential that it also occurs in the liver. Should glutathione concentrations drop, they can be increased by supplementing with cysteine or any other of the three amino acids that are used in the biosynthesis of this important if substance
The tripeptide exists in two forms: the reduced form (GSH) which contains a sulfhydryl (SH) functional group attached to the cysteinyl part of the molecule, and the oxidized form glutathione disulfide (GSSG). As electrons are lost from the reduced form, two molecules combine to create a dimer formed by a disulfide bridge, the process which can be reversed through reduction of the GSSG. Such electrons are lost during its reaction with free radicals, in which the free radicals are neutralized by the donation of an electron from the oxidized version of glutathione.
The definition of a free radical is a molecule that is lacking one electron from an electronic pair. Its prime purpose is then to steal an electron from the nearest molecule to it. In doing so, it can not only destroy that molecule, but also destroy body cells and lead, not only to premature aging, but also to some potentially fatal conditions.
It is an unusual peptide in that it involves a link between the cysteine amino grouping and the carboxyl functional group of the glutamic acid. It is a powerful antioxidant, acting as an effective free radical scavenger and protecting the body cells from the effects of free radical oxidation. However, it is on its detoxification effect in the liver that we shall focus here prior to discussing some other uses to which the body puts glutathione in its two manifestations.
Much of the detoxification is connected with the thiol group in the molecule. Take mercury for example. The thiol grouping forms a strong Hg-sulfydryl chemical bond within the liver, in the form of a glutathione-mercury chelate. In this form mercury is unable to exert any toxic effect on the body and can be excreted in the normal manner. The same reactive pathway is followed by other heavy metals that can bond to thiol groupings. In this way L-glutathione can protect the liver from the effects of a number of toxic heavy metals such as cadmium and chromium.
This is an important property of the amino acid, particularly in industrial and urban environments where the population is more prone to exposure to heavy metals than their rural counterparts. However, the end result on the glutathione is that it is removed from the body, and, particularly with city dwellers, a supplement may be required to maintain a healthy concentration of this amino acid in the body and in particular in the liver. Therefore, although L-glutathione is not considered an essential amino acid, in that it is biosynthesized within the body, a supplement is sometimes required, particularly by those who live in large cities.
It is important to consider the form in which the glutathione supplement is administered. This is because of the presence of gamma-glutamyltranspeptidase within the digestive system. This enzyme appears to destroy L-glutathione before it can be absorbed in the intestine so normal oral forms of supplementation are likely to be ineffective. Possible forms of effective administration include buccal (between the cheek and teeth) and hypodermically.
An alternative means of supplementation is to take substances such as selenium, methionine, alpha-lipoic acid, vitamin C and glutamine that stimulate the biosynthesis of glutathione. Also, since the substance utilizes the raw materials of L-cysteine, glutamic acid and glycine in its intracellular production, supplementation with these amino acids should also help to produce L-glutathione.
That said, let's return to its antioxidant properties and its effect on the liver that contains the largest stocks of glutathione in the body. It is generally regarded as the most important antioxidant in the body. It protects cellular cytoplasm from oxidation by reducing disulfide groups and maintaining a highly reducing environment within the cytoplasm. It reacts with hydrogen peroxide and other oxidative agents, and is converted to the oxidized form GSSG. It is then reduced back to GSH through the combination of the reducing agent and an enzyme. The reducing agent is nicotinamide adenine dinucleotide phosphate (NADPH), the enzyme being glutathione reductase.
The implications that this strong reducing effect has on the liver are significant. Reduced GSH L-glutathione levels have been found in patients suffering from HIV, hepatitis C and other liver diseases. Supplementation with GSH has been found to restore normal levels of glutathione to the liver, and it has been demonstrated that the treatment has improved such conditions significantly.
Atherosclerosis is a condition of the arteries caused by the deposition of plaques formed from oxidized low-density lipoproteins, otherwise known as bad cholesterol. The strong antioxidant effect of GSH prevents this from LDLs from being oxidized and deposited on the arterial wall. There are other results of glutathione supplementation that indicate the effectiveness of antioxidants in the treatment of serious liver conditions, and there are no doubts that combating the effects of free radicals and oxidizing agents within the liver has a positive effect on many potentially serious liver diseases.
Many of these are exacerbated by the generation of free radicals by relatively modern pollution sources such as pesticides, petrol and diesel emissions, tobacco fumes and various other chemical emissions. A strong antioxidant such as L-glutathione cannot be anything other than an effective means of reducing the biological effect of these oxidants. It protects not only the liver but also the lungs and cardiovascular system.
For all these reasons a supplement consisting of L-glutathione or its constituent parts, glutamic acid, cysteine and glycine, provide significant protection against the stresses and strains of modern living. Increased pollution levels and heightened oxidative stress levels within the body are playing havoc with our body defenses, and GSH is an important one of them that can easily be enhanced by supplementation. There are no known reactions to L-glutathione supplementation, but pregnant women and babies should receive expert medical advice prior to taking it.
Vitamins and Herbs
April 03, 2009 02:52 PM
The whole human body is made up of cells that contain their own genetic material. In a healthy body, these cells divide at a controlled rate, growing and repairing damaged tissues and replacing dying cells. This predetermined rate of cell division is what keeps our bodies healthy. If cells keep multiplying when new ones are not necessary, a mass of tissue, often known as a tumor, is formed. This tumor can be either benign or malignant.
Benign tumors are not cancerous and can occur anywhere in the body. Benign tumors do not cause a threat to health, do not metastasize, and do not grow back if removed. Malignant tumors are cancerous and are usually serious. Often times, they can be life-threatening. Malignant tumors grow uncontrollably, interfere with normal metabolic and organ functioning, and have the ability to metastasize and invade other tissues. If a portion of a cell’s DNA is damaged, the cell can become abnormal. When an abnormal cell divides, it forms new cells that are a photocopy of the damaged genetic material. This ongoing process occurs constantly within our bodies. The majority of the time our bodies have the ability to destroy these abnormal cells and maintain a sort of cellular equilibrium. If a crucial part of the DNA is destroyed and the abnormal cells cannot be controlled any longer, cancer forms. All cancer cells have two things in common: growing uncontrollably and having the ability to metastasize. The immune system does not recognize cancer cells as dangerous or foreign.
Although the exact cause for the cell damage that initiates the cancer process is unknown (theoretically free radical damage causes DNA damage), the chain of events that leads to cancer is very complex, and each individual body reacts differently. It is a combination of genetic, behavioral, environmental, and lifestyle factors that are thought to be involved in turning normal cells into abnormal cells, and abnormal cells into cancer.
There are also factors that are believed to slow the process, while other factors can speed up the process. Possible contributors to the development and growth of cancer can be divided into three categories: external, internal, and lifestyle. External factors include unhealthy workplace environments and exposure to air and water pollution, chemicals, pesticides, and herbicides. Included in the internal factors include both genetics and infections. Lifestyle factors are those we personally can most readily control, such as diet, smoking, drinking, and sun exposure. External and lifestyle factors account for 80 percent of cancer deaths in the United States.
Just as each of us looks different, each of our bodies has its own unique composition. Some of us may react adversely to what some of us react well to. This is why some treatments prove to be successful for some, but not for others. This is why dietary wellness and prevention is so important. If we can keep our bodies healthy and avoid known cancer-causing agents, we have a good defense against cancer in the first place.
The following nutrients and supplements are designed for persons who have been diagnosed with cancer, as well as for those who wish to enhance their chances of avoiding the disease: coenzyme Q10, colostrum, DMG, garlic, IP6, melatonin, MSM, proteolytic enzymes, selenium, 7-keto DHEA, shark cartilage, SOD, vitamin A, shiitake extract, acidophilus, chromium picolinate, flaxseed oil, grape seed extract, kelp, l-carnitine, multienzyme complex, a multi-mineral complex, multivitamin complex, NAC, raw glandular complex, taurine, and vitamin B complex. Additionally, the following herbs may be beneficial: astragalus, birch, burdock root, cat’s claw, chaparral, chuchuhuasi, cranberry, dandelion, Echinacea, fennel, green tea, licorice root, macela, milk thistle, parsley, pau d’arco, red clover, suma, cardamom, cayenne, ginger, rosemary, sage, thyme, turmeric, ragwort, wood sage, curcumin, essiac, noni, olive leaf extract, rosemary, and boswellia.
All of the above listed herbs and vitamins can help restore the body to good nutrition and help boost the immune system so the body can find and fight back against cancer. Natural vitamins and herbs are available at your local or internet health food store. When purchasing supplements, look for name brand vitamins like Solaray and Source Naturals to ensure you receive quality and you get what you pay for.
*Statements contained herein have not been evaluated by the Food and Drug Administration. Natural vitamins and herbs are not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.
June 20, 2008 02:08 PM
That common yard or roadside plant you see during the growing season can be your ally against sickness and disease. The common dandelion has many essential vitamins and minerals inherent in it that can be part of your health regimen. Dandelions are an all-natural way to promote good health when used wisely.
The dandelion root and leaves contain vitamins A, C and D, as well as the B-complexes. They also contain iron, magnesium, zinc, copper, potassium, manganese, choline, boron, calcium and silicon. Choline has shown to improve memory function. Dandelion has found use as a treatment for breast illnesses, bloating (water retention), aching joints, skin problems and gastrointestinal disorders. It is also as a gentle diuretic and a purifier for the bloodstream and liver.
This plant contains luteolin, which is an antioxidant and beneficial as an immune system enhancer. Luteolin helps inhibit the degradation and wearing down of the body's cells. What's great about dandelion and its antioxidant properties is the fact that there is no toxic effect on cells associated with it.
Dandelions are also a medicinal herb. They increase waste elimination in the body through the urine. Like green tea's effects, this excretion of water and waste can lead to weight-loss. Dandelion is available naturally, as well as in pill, liquid, tablets and tea form. The Puritans used it strictly as a vegetable, although some who eat it as a prepared dish consider it to have a bitter taste.
This plant has ranked high in many categories. It is one of the top six herbs in the Chinese herbal medicine chest. It is one of the top four green vegetables rated for overall nutritional value according to the USDA Bulletin #8, "Composition of Foods" (Haytowitz and Matthews, 1984). It is food rich in fiber. This is important because fiber is an essential component of a complete weight-loss program. Fiber absorbs fat molecules and aids in their elimination from the body. This prevents fats from absorbing into the body.
The dandelion is part of the sunflower family. It is prevalent in temperate regions in Europe, Asia and North America. This plant finds itself a big part of culinary recipes. Taking the dandelion in this form is good for health, as it is in its most natural, unprocessed state. Some use dandelion as a tea to help in the fight against fever, insomnia and jaundice. Dandelion tea can also aid those who have rheumatism, eczema, constipation and even skin diseases.
It aids digestion by stimulating stomach secretions. However, it does increase the flow of bile in one's system, so you should not take dandelion if you have obstruction of the bile ducts. While generally safe, like anything else, you should consult a doctor when trying something new in your diet. This is to make sure it doesn't have harmful side effects or interact negatively with other herbs and medications.
For women, dandelion helps because of its diuretic capabilities. This means it helps eliminate excess water from a woman's system, which causes bloating.
Those who experience premenstrual syndrome may find dandelion helps bring down their bloating and weight gain associated with water retention.
Another promising aspect of dandelion is the fact it contains lecithin. Lecithin is a lipid that contains choline primarily, along with inositol, phosphorous and linoleic acid. Lecithin elevates the brain's acetylcholine, which helps brain function. This, some researchers believe, may help slow down or stop the progression of Alzheimer's disease. Dandelion, again because of lecithin inherent in it, is beneficial for prevention of arteriosclerosis and cardiovascular disease too.
Sometimes we need to look only in our own backyards and surrounding environments to find plentiful foods that are healthy. Dandelions are one of earth's products that have found use for centuries. Whether as a recipe ingredient, a tea or a pill, dandelion is versatile. When used with care, it can help with weight-loss and be a health enhancer at the same time.
Exotic Herbs From The Amazon Basin
June 22, 2007 05:07 PM
Although many traditional herbal medicines have yet to find complete scientific corroboration in the West, it follows logically that people wouldn't use an herbal product for centuries if it didn't work.
Many of the popular herbs we all recognize as having great health benefits were only recently considered pretty exotic. Even green tea - a staple in China for centuries -has only lately gone main stream.
So it will likely be with herbs from the Amazon basin and its environs. The Amazon basin is one of the most bountiful environments on the planet. Explorers and botanists from the West have looked to this region for generations for the "next big thing." Of course, in many cases, the "next big thing" has already been in use for centuries.
In this issue of Ask the Medicine Hunter, we're going to look at some energizing and life- stimulating herbs that also happen to have great antioxidant properties, too. Best yet, many of them are available to us here from companies that practice fair trade policies.
Let's take a look at some of the herbal powerhouses coming out of the Amazon (and its nearby neighborhoods):
Maca (Lepidium meyenii) has been cultivated for a long time at least 2000 years. Related to brassica family plants like radishes, mustard and cabbage, its foliage does actually look somewhat radish-like, but grows close to the ground.
Maca is cultivated by the Andean people in Peru's central highlands, and contains a plethora of beneficial compounds that enhance overall health and vitality. The tradition of cultivating maca is an old one some strains have been found in Incan sites that date from 1600 B.C. During early European colonization, maca was used by the local native culture as a form of currency, much of the way cocoa was used by the Aztecs, further north in pre-Columbian Mexico.
Maca thrives in high altitudes - between 10,000 and 16,000 feet. The harsher the conditions, the better it grows, or so it seems. In fact, efforts to grow the plant in Central Europe haven't been as successful - maca seems to enjoy its home turf the best. In Peru, maca is a popular and beloved nutrient-packed superfood, and is commonly powdered and mixed into drinks at roadside stands throughout the Andes.
Q. I've heard of maca being used for healthy libido - are there any other benefits?
A. Maca is a natural energizer, and although it is recognized for it's libido enhancing abilities, it has other uses, too, acting as an adaptogen - similar to rhodiola or ginseng. In fact, in South America, maca is known as "Peruvian Ginseng." Though maca is not ginseng at all, some of the benefits of both plants are similar.
In any event, maca is recommended for boosting the immune system, menopause support, and hormonal balance in general. For daily use, maca is most recognized as a great source of energy and all-day endurance. Alkaloids from maca root may be partially responsible for both maca's energizing and libido boost. Research shows that maca affects the hypothalamic-pituitary (HPA) axis - boosting energy and overall aphrodisiac prowess in men and women. Maca contains novel compounds called macamides and macaenes, which have been proven in animal studies to significantly enhance energy, stamina and sexual function reasons people have been so consuming maca for 2000 years.
There are other serious reasons why maca is such an excellent plant. One group of compounds in maca is the isothiocyanates-aromatics constituents that are responsible for the "hotness" of mustards and radishes - fellow members of the brassica family. Isothiocyanates from other members of the brassica family may reduce the risk of breast and stomach cancer. Although the same constituents specifically from maca haven't beentested, it's plausible that they could have the same effects.
Q. I've heard a little about guarana extracts - is it just caffeine?
A. Guarana is widely loved for its mild stimulating effect, which is due to caffeine. But this is by no means this Amazonian herb's sole beneficial compound. Guarana (Paullinia cupana) is so logically ingrained in the culture of Brazil that it's practically a rival (actually out-sells) Coca-Cola in its soft-drink form. Like many other indigenous herbs, guarana was in use locally well before European settlement. Its Latin name comes fromthe German botanist C.F. Paullini, who first encountered the herb in the 1700s. This evergreen vine typically climbs fairly far up the Brazilian forest trees. The seed is the part that gets used. In one clinical study, guarana boosted the memory alertness of participants, even when the caffeine level per dose was a low 9 mg., as compared with approximately 100 mg for a cup of coffee. This effect suggests that other agents than caffeine contribute to a feeling of well being.
Guarana also contains powerful antioxidants including catechin, epicatechin and proanthocyanidins, which protect cells against destruction from free radicals, and impart benefits to the body's tissues and blood. The small seed of this plant is powerful in its health benefits.
Catuaba (Erythroxylum catuaba) is a common tree found in South America from Brazil to Peru, in the same genus as the coca plant. Catuaba contains components known as alkaloids. These alkaloids (called catuabine A, B, and C) are probably responsible for themental boost most people get when they take catuabe-based supplements or mixes.
There may be little confusion regarding catuaba, because various species and genus typesuse the common name. As a result, "catuaba" gets bandied around a lot, and one person'scatuaba may not be the next. Read labels carefully. The catuaba I've had the best luck with is Erythroxylum catuaba.
One of my favorite drinks in the world is coffee, and I'm sure at many people reading thisconsider it the essential part of their morning, too.
The part of coffee that we use the most is the seed of the coffee fruit - which appears as a bright, red berry. Most of the time, this fruit is sloughed off and left behind in the process of making coffee - it's really too delicate to last long in hot conditions.
But advances in technology have tapped a previously discarded resource. Though the fruit of coffee is available in any coffee-growing economy, a high antioxidant commercial extract of "coffee cherry" is now available from the fruits of coffee plants in Mexico.
Coffee fruit has many of the attributes of other dark-colored, anthcyanin-rich fruits. Coffee fruit (also referred to as "coffee cherry") appears not to be just another antioxidant, however. Current research on this once-forgotten, former castoff shows impressive abilities to decrease tumor size, and possibly even prevent their formation in the first place. It seems that the elements in coffee berry activate T-lymphocytes in such a way that mammary tumors are shrunk or simply put on hold. It will be fascinating to see how this science plays out.
Muira Puama Bark:
Muira puama (Ptychopetalum olacoides) grows between 15 to 45 feet high. Native to theAmazon basin of Brazil, the dried bark has been used for centuries as a traditional energysupport. Components include beta-sitosterol, campesterol and lupeol.
Muira puama, like other central nervous stimulants has been researched lately for its ability to boost memory retrieval and protect neural (brain) tissue. Who knows? Maybe this traditional ingredient could someday be on the cutting edge of natural medicines fighting Alzheimer's, much the way green tea and turmeric are currently. In one unpublished French study of 262 men with low libido and poor erectile function, 62% experienced significant improvement after taking an extract of Muira puama for two weeks.
Acai (Euterpe acai) berry is a traditional favorite (and readily available) food source for people in the Amazon. The tree is a tall-growing palm with berries that provide - a rich source of anthocyanins, potent purple pigments with extraordinary high antioxidant activity.
Once harvested, acai fruits decay rapidly. As with coffee fruits, special processing is the surest way to make certain the nutrients of acai berry make it to those of us outside the Amazon basin.
However, these wonderful fruits not only fight against free radical damage, but help our natural digestive enzymes and boost natural immune defenses, too. In fact, current research is investigating whether compounds in acai may have a fighting effect on leukemia, too. So far, the results have been very positive.
Look for supplements made using organically-grown, fair trade acai berry. The best companies ensure that the local people harvesting acai and the communities where they live gather more than just short-term benefits. The best companies work not just to provide jobs, but better lives for generations to come.
Q. What is sustainability and fair trade, anyway?
A. Sustainability refers to a set of naturally occurring circumstances, or intentionally designed practices and principles, which ensure that all parts or members of a situation are adequately nourished to promote their healthy continuance. In current parlance, sustainability often refers to practices and programs designed and implemented to keep natural systems healthy and flourishing. Many such programs focus on environmental protection and preservation of traditional cultures. In the world of medicinal plants, sustainable practices include organic agriculture, species management, fair trade, and benefit-sharing programs.
In other words, sustainability pays people fair wages, puts resources back into their communities, and ensures that the resources that benefit us all are going to be around for a long time. It is an earth-friendly, people-friendly concept of commerce that happily, is taking root around the world.
The traditional cultures that use - and have used - these ingredients for generations wouldn't have done so if they hadn't been effective. Fortunately we live in an era when formerly locally-used herbs are now available far beyond their previous range. We are also fortunate to have companies and individuals working hard to make sure that the people who tend and care for these precious resources are paid fairly for their efforts, andthat their families and communities benefit from this commerce as well.
The great thing about using traditional herbs and ingredients that have been gathered in this manner is that you know they'll be around for a long time.
Wellness Fizz - Fast-Acting Immune Defense
February 26, 2007 02:15 PM
NaturalCare Virus Induced Nasal Decongestant – Super Strength SinuFix
October 06, 2006 02:34 PM
Super strength SinuFix Nasal Decongestant Mist 90 percent of Germs, Viruses and Pollutants May enter your body through the nose! All of us breath in through our nose and are inundated daily with thousands of foreign micro particles. Super Strength SinuFix Mist is an innovative formula specifically designed to fight the virus induced nasal allergy/sinus/cold/flu-like symptoms that may result from exposure to germs and viruses in the air in any crowded, potentially germ-infested environment.
Germs in the Air Everywhere!
Indications: For temporary, soothing relief of virus induced nasal and sinus congestion and pressure, dry, irritated nasal membranes associated with a cold and sinusitis, irritated/swollen sinus passages, hay fever, overuse of decongestant sprays or drops, or other upper respiratory allergies (Allergic rhinitis). Helps cleanse nasal passages and promotes nasal and sinus drainage.
Wasabi Rhizome Cleanse - Supports Phase II Liver Detoxification - Wasabi Health Benefits
August 01, 2006 10:41 AM
Most people know of it as a pale-green lump on the side of their plates in Japanese restaurants—a hot, spicy accompaniment to sushi or sashimi. The fiery yet sweet taste perfectly compliments the saltiness of soy sauce and the cool delicacy of raw fish. But wasabi is much more than a burst of culinary flavor, it has been used by traditional herbalists of Japan since the 10th century and is now being rediscovered by modern health practitioners for its stunning health benefits.
Wasabi has powerful detoxification properties, in particular, it supports the immune system and cleanses the liver. Wasabi contains precursors to phytochemicals called isothiocyanates that help remove toxic substances that are stored in the liver’s fatty tissues.
The rare wasabi plant is a natural, potent support to a healthy, cleansed liver that in turn affects the detoxification and cleansing of the entire body. Source Naturals is pleased to bring you this convenient, effective addition to your wellness program.
Wasabia Japonica - Rooted In Health
The wasabi plant (Wasabia japonica) grows naturally in the mountains of Japan in the gravel and sandbars of coldwater streams and rivers. Rare and difficult to grow, it takes three years for a wasabi root or rhizome to reach maturity. Because of its popularity, wasabi is now cultivated hydroponically and in cold, wet environments outside of Japan, such as in New Zealand and Oregon. Traditionally, the rhizome was freshly grated at the table with a sharkskin grater, popular with dishes such as seafood or udon noodles. Now wasabi is usually dried into powder form and made into the pale green paste familiar to most westerners. Often, however, restaurants do not serve real wasabi; since it is so rare and expensive, a dyed horseradish paste is served in most American restaurants.
What makes wasabi so special? It comes from a good family; the brassica vegetables in the cruciferae family include such health giants as broccoli, horseradish, Brussels sprouts, cabbage, cauliflower and kale. All of these are well-known detoxifying plants, and wasabi appears to be the most amazing of them all, with detox capacities far beyond the others in the family because it is loaded with isothiocyanate precursors. This chemical not only gives wasabi its famous “fire,” it is likewise a fireball of detoxification properties.
Phase II Detox
The liver detoxifies the by-products of digestion and other harmful substances through a complex series of chemical reactions often referred to as Phase I and Phase II Detoxification. Phase I enzymes begin the process by taking the toxic molecule and changing it into a bioactive form. This process breaks down toxins. A second set of enzymes, Phase II, then neutralizes the toxin and makes it water soluble for elimination. Wasabi, with its long-chain isothiocyanate precursors, induces the Phase II enzymes. Simply stated, it is the sparkplug that starts Phase II enzymes on their work. This process, all done in the liver, supports the body’s ability to clean itself of impurities.
Part of a Complete Wellness Program
In the modern world, with so many pollutants, it is critical to your health and longevity that you cleanse these toxic compounds from your body. Wasabi, along with a whole food, high-fiber diet and reduction of alcohol consumption, supports the liver— the largest of the vital organs and the key to the digestion and elimination systems and most particularly, the body’s ability to cleanse itself. Source Naturals is pleased to bring you this exceptional product as part of your wellness program.
Depree, JA (1999) Flavour and pharmaceutical properties of the volatile sulphur compounds of Wasabia japonica. Food Research International: 31(5):329-337.
Morimitsu Y, et al. (2002) A sulforaphane analogue that potently activates the Nrf2-dependent detoxification pathway. J Biol Chem: 277:3456-3463.
Munday, R (2002) Selective induction of phase II enzymes in the urinary bladder of rats by allyl isothiocyanate, a compound derived from Brassica vegetables.
Nutrition and Cancer: 44(1):52-59.
Watanabe, M (2003) Identification of 6-methylsulfinylhexyl isothiocyanate as an apoptosis-inducing component in wasabi. Phytochemistry: 62(5):733-739.
Rose, P (2000) 7-methylsulfinylheptyl and 8- methylsulfinyloctyl isothiocyanates from watercress are potent inducers of phase II enzymes. Carcinogenesis: 21(11):1983-1988.
Benefits of Best Alpha Lipoic 35!
February 12, 2006 03:11 PM
Benefits of Alpha Lipoic Acid
October 13, 2005 05:08 PM
Benefits of Alpha Lipoic Acid
Alpha-lipoic Acid––the "Ideal Antioxidant"
The antioxidant potential of a substance is based on a number of criteria, including:
The "ideal antioxidant" would meet all the above criteria. Very few antioxidants do, yet a particular antioxidant with but a few of the characteristics is still valuable and effective. Vitamin E, for example, is one of the most important dietary antioxidants, yet it only works in fatty environments such as cell membranes.
As a team, ALA and DHLA come close to the ideal, for the following reasons:1,2,3
DHLA-regenerates vitamin C, vitamin E and glutathione
Within the cell, antioxidants work as a team to keep free radicals from damaging cell structures. In order to neutralize a free radical, an antioxidant such as vitamin C must give up an electron, which mean it becomes oxidized. Before it can function as an antioxidant once again, it must be regenerated back to its "reduced" form, by gaining an electron to replace the donated electron. For this, it needs the help of other antioxidants. Vitamin C, vitamin E and glutathione are key antioxidants that can be generated by cycling between their oxidized and reduce forms. This is necessary to maintain the balance between oxidation and its reverse––the neutralization of free radicals by antioxidants.
DHLA is an essential component in the interaction between these antioxidants.4 Studies show that addition of alpha-lipoic acid to liver tissues results in increased vitamin C levels. It has been found that DHLA is responsible for regenerating vitamin C, which in turn regenerates vitamin E.3 DHLA also converts glutathione from its oxidized form back into its free radical scavenging reduced form.3,5 The ALA/DHLA pair is thus vital for prevention of "oxidative stress," which occurs which the balance is tipped in favor of oxidation in cells.4 DHLA helps preserve antioxidants in both the watery cell interior and the fatty structure of cell membranes.6 Evidence from animal studies suggests that DHLA protects the brain against free radical damage.7
Alpha-lipoic acid is a key factor in the cellular process that metabolizes glucose to produce energy for cellular functions. The importance of ALA’s role in blood sugar metabolism is evidenced in studies on ALA and type-2 diabetes. In a small pilot study, 13 people with type-2 diabetes showed improved utilization of glucose in muscle tissue in response to intravenous administration of ALA.8 In a four week controlled multicenter trial, 74 people with type-2 diabetes took ALA in oral doses of 600, 1200 or 1800 mg per day. After 4 weeks, the normal lowering of blood sugar levels in response to insulin improved.9 In vitro studies have shown that ALA has a positive effect on insulin-stimulated uptake of glucose by muscle cells.10
1. Packer, L.. Witt, E., Tritschler, H. Alpha-lipoic acid as a biological antioxidant. Free Radical Biology and Medicine 1995;19(2):227-50.
2. Suzuki, Y., et al. Thioctic acid and dihydrolipoic acid are novel antioxidants which interact with reactive oxygen species. Free Rad. Res. Comms. 15(5):255-63.
3. Biewenga, G., Haenen, G., Bast, A. The pharmacology of lipoic acid. Gen. Pharmac. 29(3):315-31.
4. Serbinova, E. Maitra, I., Packer, L. The synergy between vitamin E and alpha-lipoic acid--–possible relationship against oxidative stress in vivo. Life Chemistry Reports 1994;12:17-21.
5. Bast, A. Haenen, G. Interplay between lipoic acid and glutathione in the protection against microsomal lipid peroxidation. Biochimica et Biophysica Acta 1988; 963:558-561.
6. Kagan, V. et al. Dihydrolipoic acid––a universal antioxidant both in the membrane and in the aqueous phase. Reduction of peroxyl, ascorbyl and chromanoxyl radicals. Biochem Pharmacol 1992;44(8):1637.
7. Prehn, J. et al. Dihydrolipoate reduces neuronal injury after cerebral ischemia. J Cereb Blood Flow Metab 1992;12(1):78-87.
8. Jacob, S. et al. Enhancement of glucose disposal in patients with type-2 diabetes by alpha-lipoic acid. Arzneimittelforschung 1995;45(8):872-4.
9. Jacob, S et al. Oral administration of RAC-alpha-lipoic acid modulates insulin sensitivity in patients with type-2 diabetes mellitus: a placebo-controlled pilot trial. Free Radical Biology & Medicine 1999;27(3/4):309-14.
10. Estrada, D. et al. Stimulation of glucose uptake by the natural coenzyme alpha-lipoic acid/thioctic acid: participation of elements of the insulin signaling pathway. Diabetes 1996;45(12):1798-804.
Padma Basic for Health and well being
August 23, 2005 06:32 PM
Ancient Tibetan Formula Supports Today’s Health Concerns
The world can be a stressful place. We are constantly bombarded with pollutants, placed in stressful situations and exposed to immune compromising environments. Modern times can take their toll on the body, the heart and the immune system.
Source Naturals can help with the ancient Tibetan formula Padma Basic, which contains 20 healing natural ingredients for supporting healthy circulation, immune function and antioxidant protection.
In traditional terms, Padma was used as a cooling formula that enhances wind. Between stress and not having enough time to eat, sleep or exercise, excess heat or irritation can build up in the body. That irritation can cause unnecessary oxidative stress from free radicals and stagnation so your body systems don’t flow harmoniously. This can lead to imbalances in your circulatory and immune system. Padma provides a comprehensive blend of ingredients, including many antioxidants, which cool this heat and promote wind, or healthy circulation.
Best Mangosteen 10% Extract with xanthone flavonoids
July 27, 2005 11:31 AM
• Defends Against Free Radicals*
The xanthone flavonoids and other compounds in mangosteen fruit are responsible for its high level of antioxidant activity. In vitro tests have been conducted on XanoMax? mangosteen 10% extract to determine the level of free radical scavenging ability in both watery and fatty environments. A major test recognized as the industry standard for measuring antioxidant activity is known as the ORAC (Oxygen Radical Absorbance Capacity) assay.
The ORAC test is an in vitro assay that works by measuring the amount of free radical damage done to a fluorescent probe (measured by a change in probe intensity). Antioxidants lessen the damage to the probe fluorescence, which indicates a reduction in free radical damage. This measure is used to quantify the antioxidant’s (or combination of antioxidants) capacity to quench free radicals. This quantification is known as the total ORAC value. The total ORAC value provides a relative measure of total antioxidant strength of any substance, allowing for comparison of different mixtures. A high ORAC value corresponds to a high total in vitro antioxidant capacity.
The development of the ORAC test has led to a number of commonly eaten foods being assessed in terms of total ORAC scores per serving. Similarly, particular combinations of antioxidants, such as those in nutritional formulas, can also be assessed for their total ORAC scores. This has led to the ability to determine the potential usefulness of a particular supplement in increasing overall antioxidant capacity.
When XanoMax? mangosteen 10% extract was tested for ORAC value, the resulting antioxidant potential was over 3,500 ORAC units per gram of extract. This result is extremely high. ORAC values of compounds vary with their nutrient concentration, moisture content and other factors. For comparison purposes, whole blueberries, considered to be a rich source of antioxidants, had an ORAC value of 61 units per gram, while pomegranate tested at 105 ORAC units per gram.1 XanoMax? mangosteen extract is a potentially rich source of beneficial antioxidants*
• Maintains Healthy Immune Function*
Evidence from several animal and in vitro studies on various cell lines suggests that components of mangosteen fruit extract may play a role in modulating several factors important to healthy immune function. Of the active components, xanthone derivatives seem to play the major role in influencing parameters of immune function in animals and in vitro models. Mangostin is the xanthone derivative that most of these studies have focused on.
A study published in 2002 assessed the effects of mangosteen extracts on the release of histamine from rat cell lines. The comparison was made to extracts of a plant frequently used in Japan, Rubus suavissimus, which is a known inhibitor of IgE-mediated histamine release from these cells. The assay showed that the mangosteen extracts used inhibited the release of histamine from these cells more potently than the extract of Rubus suavissimus. In addition, the authors compared the two herbs for prostaglandin E2 synthesis in another rat cell line and found that the mangosteen extract potently inhibited prostaglandin E2 synthesis in this in vitro trial, whereas the other herb had no effect.2
An earlier study was performed in guinea pig tracheal and rabbit thoracic aortal tissue. In this study, alpha mangostin prevented histamine-induced contraction and was shown to be a competitive histamine receptor antagonist in the smooth muscle tissue of the trachea and aorta of the animals selected. The results seen in this laboratory study were determined to be concentration-dependent. The authors suggested that alpha mangostin should undergo further studies to determine its effects on the modulation of the histamine response.3
Further in vitro assessments point to potential actions of mangosteen components in modulating effectors of occasional inflammation in the immune system. Studies in rat glioma cells suggest that mangostins inhibit enzymatic reactions that can lead to the production of specific prostaglandins.4,5 By inhibiting these reactions, mangostins may play a role in modulating overall immune function, promoting healthy immunity.
Mangosteen and its constituents hold much promise for their potential ability to enhance immune function and promote health. In addition to being a highly nutritious food, mangosteen extract is full of antioxidant activity. It has an extremely high ORAC value and a great potential for enhancing free radical defenses in the body. Best Mangosteen 10% extract contains XanoMax ™, which is standardized to a high level of active mangostin, the class of compounds shown in in vitro studies to benefit certain aspects of immune function. Safety Scientific References
GARLIC AS AN ANTIOXIDANT
June 25, 2005 10:20 AM
GARLIC AS AN ANTIOXIDANT
The term “antioxidant” has become a buzz word over the last decade. Defending ourselves against a wide array of chemicals, heavy metals, pollutants, radiation and poor nutrition has become a vital area of scientific focus and research. Oxidizing agents or free radicals attack our bodies constantly and have the potential to damage our cells, which compresses human tissue.
Substances which have been found to help protect us from the cellular damage caused by free radicals include vitamin C, bioflavonoids, vitamin E, vitamin A, beta carotene and selenium to name a few. Garlic is not usually found on standard antioxidant lists and probably should be.
Garlic has an abundance of sulfhydryl which is an excellent antioxidant. It’s important to know that raw garlic did not demonstrate this ability. In fact, raw garlic actually has some oxidant action, which is not desireable. Garlic can also help to lessen free radical damage because it has the ability to protect against radiation. In this regard, it may significantly decrease our risk of developing certain degenerative diseases such as cancer and premature aging. In addition, anyone undergoing radiation or chemotherapy should supplement their diet with garlic. “Based on a number of studies conducted by research teams from throughout the world, scientists have concluded that part of the preventive effect of garlic against cancer is due to protection against free radical damage. But that protection extended beyond the mere ability to protect against disease. The ability of garlic to protect against free radical damage may have yet another important benefit to cancer victims: it can, according to several published articles, protect against the damage that results from radiation treatment and chemotherapy commonly given to many cancer patients.” 44 Garlic also contains a number of amino acids which are required for the formation of an enzymatic antidote to free radical pathology which is created by cigarette smoke and other pollutants. Cysteine, glutamine, isoleucine and methionine found in garlic help to protect the cells from free radical damage.
Garlic works as an antioxidant the same way that onions, and green chilies do. In his book The Miracle of Garlic, Paavo Airola states:
“An Indian study showed that garlic exhibited a high antiox idant property as determined by the peroxide values of the products by the swift stability test. Garlic restrained the development of all characteristic indexes of rancidity (acids, peroxides, iodine no. etc.). Garlic retained its antioxidant property for a half year after harvesting.”45
Because our food, air, water and environments are heavily contaminated with pollutants of all kind including food additives, preservatives, artificial colorings, flavorings, sweeteners, chemical fertilizers, etc., garlic should become a permanent addition to our nutritional array of supplements.