Search Term: " Fascinaing "
Fascinating study shows vitamin C reduces the risk of cognitiveimpairment
January 18, 2019 09:17 AM
The scientific journal Nutrients recently published a study from New Zealand which suggests that Vitamin C plays an important part in preventing age-related cognitive impairment. The trial involved 400 New Zealanders over 50, who had their blood levels of Vitamin C checked and completed cognitive testing. Not only did higher levels of Vitamin C in the blood reduce the risk of cognitive impairment, but levels indicative of a moderate deficiency caused this risk to double! Higher levels of Vitamin C were also associated with better metabolic health.
"Recently, a team of scientists from New Zealand found that vitamin C can help reduce the risk of cognitive impairment as you age."
Read more: https://yournews.com/2018/12/05/774377/fascinating-study-shows-vitamin-c-reduces-the-risk-of-cognitive/
Pay Attention To This Detail When You Put Your Palms Together
July 30, 2017 12:14 PM
Put your hands together, palms side by side, and you will notice two lines one on each palm. If the line of the left palm is higher than the right palm it means that you are more likely to take time in finding an appropriate relationship instead of rushing into one. If the lines are at equal height, it means that you are a highly confident and routine person, and that you seek out long term relationships. Lastly if the left line is lower than the right you find yourself as a rebel to society, you choose your own paths and are very intelligent. You are most attracted to older wiser individuals, one could say you seek knowledge.https://www.youtube.com/watch?v=rh8_-ZDm0bU&rel=0
"One important line is that of the love line, otherwise known as the love line. Running from the edge of the Palm under the little finger towards the area of the middle finger or forefinger joins the hand, this line has been found to have deep meaning in the area of love and affection."
Prostate cancer breakthrough: Combination of three plant-based nutrients found to MELT AWAY prostate cancer cells
July 03, 2017 12:14 PM
A study by the University of Texas, Austin, has found that there is potential for treatment of prostate cancer using compounds found in common foods. ursolic acid, commonly found in apple peel, curcumin, found in the spice tumeric, and resveratrol, found in red grapes. These three compounds were tested together as a new combination approach to creating treatments. Working together, these compounds caused shrinkage of tumor cells and changed the way the cancerous cells metabolized nutrients that allow them to grow out of control.
"A fascinating new study published in Precision Oncology has found that a combination of three plant-based nutrients “melts away” prostate cancer cells."
Read more: http://www.naturalnews.com/2017-06-30-prostate-cancer-breakthrough-combination-of-three-plant-based-nutrients-found-to-melt-away-prostate-cancer-cells.html
Vitamin K2: 9 Uses and Benefits
January 13, 2017 12:59 PM
Vitamin K2 is often overlooked in the normal diet, yet K2 is is known to be essential to bone health and heart tissue health. When balanced with Vitamin D3 and magnesium, K2 helps bind those minerals to the bone matrix. Vitamin K2 can be found in certain foods or through supplements for those interested in enhancing their uptake of this important vitamin.
"Vitamin K is a fat soluble vitamin that is important for blood clotting and that contributes to a healthy heart, bones and immune system."
New antibiotics discovered by sifting through the human microbiome
December 01, 2016 08:59 AM
For Computer software to help discover new antibiotics is incredible. It's fascinating how far we have come with technology. Synthesizing is such an interesting concept. The experiments that suggested that the humimycins worked by inhibiting an enzyme that bacteria use to build their cell walls - and once that cell-wall building pathway is interrupted, the bacteria died. Wow, such a wonderful discovery.
"The software initially identified 57 potentially useful gene clusters, which the researchers winnowed down to 30."
Gut bacteria unleash anti-aging power of pomegranates
November 21, 2016 01:09 PM
Pomegranates may hold a more significant role than just tasting delicious. There are studies underway that aim to prove the anti-aging benefits of the fruit. It is believed that the breakdown of pomegranate in the gut causes a release of urolithin A, which in turn boosts the cells’ ability to clean up after itself. Without the buildup of mitochondrial matter that happens without urolithin A, the body doesn’t age as quickly.
"As we age, an important process that our cells rely on for energy slows down and begins to malfunction."
Benefits of Natural Honey?
December 19, 2012 03:06 PM
Raw And Natural Honey
Raw honey is one of the oldest sweetening agents known to mankind. This substance is laden with lots of substances that have proven useful to humans from time immemorial. In fact, many cultures and civilizations have used this substance with a great deal of success which underscores its importance even in modern times. Without wasting much time, we shall delve straight into some of the most fascinating health benefits of natural honey.
While many people know that honey is basically a sweetening agent, few of them know that honey good for the skin. Ancient Greeks pioneered the use of honey as skin mask. Honey can be combined effectively with oils and aloe vera to produce fantastic skin masks. The resulting mixture can be used to cure a great deal of skin problems from acne scars, blemishes, and dark spots on the skin.
Honey is also laden with nutrients and elements that nourish and moisten the skin leaving you with a soft texture and young looks. Honey is packed with powerful amino acids and enzymes that revitalize the skin.
So, instead of going for expensive creams and moisturizers, why not tap the power of raw honey?
Did you also know that raw honey is a powerful antibacterial agent? Scientists believe that pure honey can cleanse pores and eliminate microbes leaving you with a natural looking and healthy skin. Besides that, natural honey can act as an effective sunblock. It has antioxidant properties that can shield the skin from the effects of harmful ultraviolet rays.
Moving away from the skin, natural honey is also a great remedy for ulcers and abdominal problems. Honey has agents that attack bacteria while strengthening the stomach linings at the same time. Natural honey can also be used as remedies for moles and cough and chest problems.
Certainly, there is a whole lot more you can do with raw home. This underscores the fact that natural honey is a powerful substance with multiple purposes.
Fight Inflammation With Herbs from Planetary Herbals
June 02, 2010 04:39 PM
Our modern lives have untold benefits, as well as challenges. Our dependence on man-made toxic chemicals, junk food, nutrient imbalanced diets, and our stressful, sedentary lifestyles can alter our biochemical metabolism and affect our health.
These lifestyles and environmental change can challenge immune health, so that the various components of the immune system are not able to carry out their protective functions. Or our immune systems can go into overdrive, often leading to a state called metabolic inflammation.
A Powerful Herbal Blend
Inflamma-Care is a potent, herbal response to the metabolic inflammation that can result from inappropriate immune response. The main component of inflama-care is the rhizome of the curcuma spicies, long used as a spice in India. Known worldwide as turmeric (curcuma longa), it acts as an anti-inflammatory by inhibiting the activities of cytokines – inflammation messengers.
This world-renowned spice is supported by boswellia, which inhibits pro-inflammatory enzymes, and ginger an antioxidant that inhibits prostaglandin and leukotriene biosynthesis. Other herbs in the formula that inhibit inflammatory action include willow bark, Chinese skullcap, corydalis, holy basil, and hops.
Inflama-care also contains systemic enzymes to clear and protect the arteries and circulatory system. Systemic enzymes like bromelain and papain cleanse the bloodstream and enable the blood to flow smoothly. A free-flowing bloodstream helps the body by circulating important nutrients to the cells while clearing the body of wastes.
Immune Activating Mushroom
Planetary Herbals also offers you new Full Spectrum Chaga in 1000mg tablets and a 1:4 liquid extract. Preliminary studies suggest that chaga triggers immune responses and protects the cells with antioxidant activity.
Chaga is a mushroom that is found attached to trees like birch, alder, beach, and other hardwoods, throughout the northern latitudes. A polyphore, the mushroom looks somewhat like coal – a brownish black mass often seen in tree trunks. In China, Siberia, Finland, Japan, Poland and North America, ancient and native peoples have long known the benefits of chaga. In an acient treaties, the Chinese monk shen nog declared in 100 BC that chaga is “a precious gift of nature.”
In modern research, chaga has been shown to have 215 phytonutrients, including 29 beta-glucans. Chaga also absorbs a nutrient from the outer birch tree bark: betulin, a natural anti-inflammatory. Among the components in chaga are triterpenes, sterols, beta-glucans, flavonoids, melanins, polyphenols, saponins, lignin, amino acids, vitamins, minerals, and fiber. This fascinating combination of nutrients is being studied worldwide.
The PhytoDynamic Difference
Both inflama-care and full spectrum chaga are formulated with a profound understanding of the ways in which plant compounds interact with human physiology. Planetary Herbals phytodynamic principles draw on herbal tradition, scientific research, and a level of clinical expertise unmatched in the natural products industry. The result: herbal products unsurpassed for quality and consumer satisfaction.
Artichoke Leaves Provide Stimulating Digestion Benefits
February 22, 2008 10:46 AM
The leaves from the plant of this familiar food are found to be beneficial to our digestion and metabolism, potentially reducing cholesterol. The artichoke has long been eaten as a vegetable, and has been ascribed many beneficial attributes. Artichokes were cultivated in the ancient Mediterranean and enjoyed great popularity in the thriving Roman Empire. From then until its mid-16th century reemergence, the artichoke hovered in sporadic obscurity.
Greek philosopher Theophrastus, a recognized naturalist, wrote of artichoke cultivation in Sicily and Italy around 300 B.C. Several centuries later, physicians and naturalists in Greece and Rome collected and recorded information on the health remedies resulting from intake of the artichoke and its preparations. The artichoke was also considered an aphrodisiac and a delicacy; to this day that estimation still remains.
Along with possessing a pleasantly robust and slightly bitter flavor, the fleshy lobes of the artichoke contain vitamins A and C, dietary magnesium, folic acid, fiber, as well as potassium and manganese, among other essential nutrients.
But the story doesn’t end there. The oft-thrown away serrated leaves of the artichoke plant, a member of the thistle family, contain even more health benefits than their edible counterpart. What most people are familiar with is actually the edible flower bud of the artichoke plant.
The plant’s leaves contain two key substances with health-giving attributes, the main one being cynarin. What is fascinating about this compound is that fresh artichoke leaves only contain trace amounts of cynarin. During the extraction and drying process, the levels rise due to chemical changes that occur during the process. Artichoke leaf extract contains beneficial levels of this compound that provides maximum benefit when ingested. Before more potent pharmaceuticals were developed by drug companies, synthetic cynarin preparations were prescribed to patients with high cholesterol.
Cynarin stimulates bile secretion in the liver and gallbladder; working as a digestive aid to break down fats and cholesterol. Additionally, increased bile production assists the digestive track in eliminating toxins from the liver.
Bile is formed in the liver, created by the combination of cholesterol and triglycerides. Often times these two terms are considered negative, but not all cholesterol is bad cholesterol. Some forms are necessary for normal body function. Once the bile is formed in the liver, it is stored in the gallbladder. Bile not only works to eliminate toxins, it also emulsifies fats to allow them to be digested and metabolized. Without bile the digestive track would be a disaster, and the body would be unable to absorb fat soluble vitamins.
The process by which artichoke leaf extract is thought to lower cholesterol levels is made up of two parts. More bile means the liver has more power and efficiency in breaking down and eliminating cholesterol. In addition to the increased ability to get rid cholesterol, artichoke leaf extract has been shown to inhibit cholesterol production in the liver. This second attribute is thought to come from the levels of luteolin in the extract.
Luteolin, a flavonoid, is an antioxidant efficient at fighting free radicals and reinforcing the functions of the immune system. Additionally, luteolin has been shown in studies to increase carbohydrate metabolism and prevent LDL-cholesterol oxidation.
Medical science is only beginning to reveal the details of how artichoke leaf extract works to improve cardiovascular and digestive health, while ancient physicians and traditional healers had a hunch all along.
Exotic Herbs From The Amazon Basin
June 22, 2007 05:07 PM
Although many traditional herbal medicines have yet to find complete scientific corroboration in the West, it follows logically that people wouldn't use an herbal product for centuries if it didn't work.
Many of the popular herbs we all recognize as having great health benefits were only recently considered pretty exotic. Even green tea - a staple in China for centuries -has only lately gone main stream.
So it will likely be with herbs from the Amazon basin and its environs. The Amazon basin is one of the most bountiful environments on the planet. Explorers and botanists from the West have looked to this region for generations for the "next big thing." Of course, in many cases, the "next big thing" has already been in use for centuries.
In this issue of Ask the Medicine Hunter, we're going to look at some energizing and life- stimulating herbs that also happen to have great antioxidant properties, too. Best yet, many of them are available to us here from companies that practice fair trade policies.
Let's take a look at some of the herbal powerhouses coming out of the Amazon (and its nearby neighborhoods):
Maca (Lepidium meyenii) has been cultivated for a long time at least 2000 years. Related to brassica family plants like radishes, mustard and cabbage, its foliage does actually look somewhat radish-like, but grows close to the ground.
Maca is cultivated by the Andean people in Peru's central highlands, and contains a plethora of beneficial compounds that enhance overall health and vitality. The tradition of cultivating maca is an old one some strains have been found in Incan sites that date from 1600 B.C. During early European colonization, maca was used by the local native culture as a form of currency, much of the way cocoa was used by the Aztecs, further north in pre-Columbian Mexico.
Maca thrives in high altitudes - between 10,000 and 16,000 feet. The harsher the conditions, the better it grows, or so it seems. In fact, efforts to grow the plant in Central Europe haven't been as successful - maca seems to enjoy its home turf the best. In Peru, maca is a popular and beloved nutrient-packed superfood, and is commonly powdered and mixed into drinks at roadside stands throughout the Andes.
Q. I've heard of maca being used for healthy libido - are there any other benefits?
A. Maca is a natural energizer, and although it is recognized for it's libido enhancing abilities, it has other uses, too, acting as an adaptogen - similar to rhodiola or ginseng. In fact, in South America, maca is known as "Peruvian Ginseng." Though maca is not ginseng at all, some of the benefits of both plants are similar.
In any event, maca is recommended for boosting the immune system, menopause support, and hormonal balance in general. For daily use, maca is most recognized as a great source of energy and all-day endurance. Alkaloids from maca root may be partially responsible for both maca's energizing and libido boost. Research shows that maca affects the hypothalamic-pituitary (HPA) axis - boosting energy and overall aphrodisiac prowess in men and women. Maca contains novel compounds called macamides and macaenes, which have been proven in animal studies to significantly enhance energy, stamina and sexual function reasons people have been so consuming maca for 2000 years.
There are other serious reasons why maca is such an excellent plant. One group of compounds in maca is the isothiocyanates-aromatics constituents that are responsible for the "hotness" of mustards and radishes - fellow members of the brassica family. Isothiocyanates from other members of the brassica family may reduce the risk of breast and stomach cancer. Although the same constituents specifically from maca haven't beentested, it's plausible that they could have the same effects.
Q. I've heard a little about guarana extracts - is it just caffeine?
A. Guarana is widely loved for its mild stimulating effect, which is due to caffeine. But this is by no means this Amazonian herb's sole beneficial compound. Guarana (Paullinia cupana) is so logically ingrained in the culture of Brazil that it's practically a rival (actually out-sells) Coca-Cola in its soft-drink form. Like many other indigenous herbs, guarana was in use locally well before European settlement. Its Latin name comes fromthe German botanist C.F. Paullini, who first encountered the herb in the 1700s. This evergreen vine typically climbs fairly far up the Brazilian forest trees. The seed is the part that gets used. In one clinical study, guarana boosted the memory alertness of participants, even when the caffeine level per dose was a low 9 mg., as compared with approximately 100 mg for a cup of coffee. This effect suggests that other agents than caffeine contribute to a feeling of well being.
Guarana also contains powerful antioxidants including catechin, epicatechin and proanthocyanidins, which protect cells against destruction from free radicals, and impart benefits to the body's tissues and blood. The small seed of this plant is powerful in its health benefits.
Catuaba (Erythroxylum catuaba) is a common tree found in South America from Brazil to Peru, in the same genus as the coca plant. Catuaba contains components known as alkaloids. These alkaloids (called catuabine A, B, and C) are probably responsible for themental boost most people get when they take catuabe-based supplements or mixes.
There may be little confusion regarding catuaba, because various species and genus typesuse the common name. As a result, "catuaba" gets bandied around a lot, and one person'scatuaba may not be the next. Read labels carefully. The catuaba I've had the best luck with is Erythroxylum catuaba.
One of my favorite drinks in the world is coffee, and I'm sure at many people reading thisconsider it the essential part of their morning, too.
The part of coffee that we use the most is the seed of the coffee fruit - which appears as a bright, red berry. Most of the time, this fruit is sloughed off and left behind in the process of making coffee - it's really too delicate to last long in hot conditions.
But advances in technology have tapped a previously discarded resource. Though the fruit of coffee is available in any coffee-growing economy, a high antioxidant commercial extract of "coffee cherry" is now available from the fruits of coffee plants in Mexico.
Coffee fruit has many of the attributes of other dark-colored, anthcyanin-rich fruits. Coffee fruit (also referred to as "coffee cherry") appears not to be just another antioxidant, however. Current research on this once-forgotten, former castoff shows impressive abilities to decrease tumor size, and possibly even prevent their formation in the first place. It seems that the elements in coffee berry activate T-lymphocytes in such a way that mammary tumors are shrunk or simply put on hold. It will be fascinating to see how this science plays out.
Muira Puama Bark:
Muira puama (Ptychopetalum olacoides) grows between 15 to 45 feet high. Native to theAmazon basin of Brazil, the dried bark has been used for centuries as a traditional energysupport. Components include beta-sitosterol, campesterol and lupeol.
Muira puama, like other central nervous stimulants has been researched lately for its ability to boost memory retrieval and protect neural (brain) tissue. Who knows? Maybe this traditional ingredient could someday be on the cutting edge of natural medicines fighting Alzheimer's, much the way green tea and turmeric are currently. In one unpublished French study of 262 men with low libido and poor erectile function, 62% experienced significant improvement after taking an extract of Muira puama for two weeks.
Acai (Euterpe acai) berry is a traditional favorite (and readily available) food source for people in the Amazon. The tree is a tall-growing palm with berries that provide - a rich source of anthocyanins, potent purple pigments with extraordinary high antioxidant activity.
Once harvested, acai fruits decay rapidly. As with coffee fruits, special processing is the surest way to make certain the nutrients of acai berry make it to those of us outside the Amazon basin.
However, these wonderful fruits not only fight against free radical damage, but help our natural digestive enzymes and boost natural immune defenses, too. In fact, current research is investigating whether compounds in acai may have a fighting effect on leukemia, too. So far, the results have been very positive.
Look for supplements made using organically-grown, fair trade acai berry. The best companies ensure that the local people harvesting acai and the communities where they live gather more than just short-term benefits. The best companies work not just to provide jobs, but better lives for generations to come.
Q. What is sustainability and fair trade, anyway?
A. Sustainability refers to a set of naturally occurring circumstances, or intentionally designed practices and principles, which ensure that all parts or members of a situation are adequately nourished to promote their healthy continuance. In current parlance, sustainability often refers to practices and programs designed and implemented to keep natural systems healthy and flourishing. Many such programs focus on environmental protection and preservation of traditional cultures. In the world of medicinal plants, sustainable practices include organic agriculture, species management, fair trade, and benefit-sharing programs.
In other words, sustainability pays people fair wages, puts resources back into their communities, and ensures that the resources that benefit us all are going to be around for a long time. It is an earth-friendly, people-friendly concept of commerce that happily, is taking root around the world.
The traditional cultures that use - and have used - these ingredients for generations wouldn't have done so if they hadn't been effective. Fortunately we live in an era when formerly locally-used herbs are now available far beyond their previous range. We are also fortunate to have companies and individuals working hard to make sure that the people who tend and care for these precious resources are paid fairly for their efforts, andthat their families and communities benefit from this commerce as well.
The great thing about using traditional herbs and ingredients that have been gathered in this manner is that you know they'll be around for a long time.
Aloe Vera’s Healing Properties Recognized 1500 years before Christ
April 21, 2007 01:53 PM
Fifteen centuries before the birth of Christ, Egyptian writings acclaimed the miracle plant we know as Aloe Vera, even then referred to as an ancient cure. Cleopatra, Alexander the Great and Aristotle were fans of this strange succulent prized for its soothing, healing and analgesic ability. Indians in central and South America used it to treat burns, kidney and bladder infections, dysentery, stomach and intestinal disorders.
The pulp of the plant has been used to reduce swelling and pain from injuries, while in Mexico its used to treat arthritis and gout. For many years people have kept aloe plants around for emergency burns.
We took a good look at this fascinating botanical wonder. Of the 200 plus varieties, we quickly found that only five or six fit the enzymatic structure for the cosmetic and so-called “medicinal properties” mentioned.
Then while we were studying these succulents in their natural desert setting, we observed the roadrunner bird drinking the juice of the aloe vera, passing up many aloe plants to get to a particular variety, Aloe Barbadensis Miller. We then studied acre after acre and found the roadrunner “peck marks” only on one particular species. The other aloe plants were untouched. In studying this species of plant more carefully, our Houston lab found that, indeed it had much different gel than other aloes.
The products now labeled as Georges “Always Active” Aloe are exclusively from Aloe Barbadensis Miller, the Roadrunners’ choice. George Warren, an Independent research chemist in Houston, Texus developed the special processing method that prevents the spoilage without diminishing the essential properties of the Aloe Vera plant. This new method completely eliminates the anthraquinones that are mildly toxic and can cause irritation to the digestive tract. Aloins are also removed, which give a bitter taste (and the Greenish color) to Aloe Vera juices along with the starches and sugars from the polysaccharide molecular chain and thus, George “Always Active” Aloe requires no refrigeration, and will not spoil in its natural state. This method adds no water, no preservatives and no chemicals of any kind. The finished product looks and tastes like spring water.
April 09, 2007 05:02 PM
EpiCor® is a unique and novel dietary supplement used for support of immune health, with a fascinating history of discovery. In 1943, a company in
Interestingly, when the company became self-insured, they became aware of unusually low rates of illness in employees that worked in the manufacturing plant for this animal product. This led to very low increases in their insurance premiums over the years compared to other companies, saving them quite a lot of money. Hence they began to investigate what might be the cause of the “healthfulness” of the employees at the fermentation plant. This investigation and subsequent research studies led to the formation of a new company called Embria Health Sciences, which now produces EpiCor® as a supplement for humans to support immune system health.1 Doctor’s Best® is proud to now offer the benefits of EpiCor® to its customers.
Beneficial Support of the Immune System and Activation of Natural Killer (NK) Cells in vitro*
A comparison study was performed on blood from 10 fermentation plant workers compared to that from 10 age and gender matched controls. The fermentation plant workers had several immune cell parameters that appeared superior to the control group. These included decreased levels of CD8 cells resulting in significantly increased CD4 to CD8 ratios, significantly improved cytotoxic natural killer (NK) cell activity even though total NK cells were decreased in number, higher killing efficiency of NK cells, significantly increased levels of secretory IgA, increased numbers of EpiCor™ specific antibodies, higher levels of red blood cell intracellular glutathione, and significantly lower levels of immune complexes. These results represent benefits on various cellular players of both the specific and innate parts of the immune system.1,3,4
NK cells are one of the first lines of defense used by the immune system. An in vitro study performed on human cells showed that NK cells were activated after incubation with EpiCor®, as evaluated by expression of the CD69 activation marker. The CD25 marker (IL-2 receptor) was also induced in the NK cells, although to a lesser degree.1,2 B cell activation was also noted through increased expression of CD80 and CD86 markers.2 Immediate increases in calcium levels were evident in peripheral blood mononuclear cells after exposure to EpiCor®, suggesting increased activation through calcium regulation.2
High Metabolite Immunogen*: Nutrient Make-up
Production of EpiCor® utilizes the common and harmless bakers or brewers yeast Saccharomyces cerevisiae in a patented process called MetaGen4™, a multi-stage fermentation and drying process. It differs from other yeast products in that it contains both the yeast itself as well as the metabolites or “nutrilites” formed by the fermentation process, which are present in the media.1 Together the media containing the metabolites and the yeast are dried to form EpiCor®. Analysis of EpiCor® reveals that it contains a mixture of natural polyphenols, phytosterols, beta-glucans, mannan oligosaccharides, fiber, trace amounts of B vitamins and minerals, as well as a host of other nutritional compounds.1,2
Beneficial Antioxidant Activity*
EpiCor® was tested for antioxidant activity in an in vitro assay called the Oxygen Radical Absorbance Capacity assay (ORAC). In this assay, EpiCor® was shown to have a total ORAC antioxidant level of 610 micromol TE (tocopherol (vitamin E) equivalents) units (ORAC units) per gram dry weight, which soared above other high antioxidant level foods such as cranberries (93 ORAC units per gram dry weight) and blueberries (62 ORAC units per gram dry weight).1,3,5
In another study, freshly isolated human neutrophils were treated with EpiCor® followed by the free radical generator hydrogen peroxide. Cells were treated with a dye that fluoresces when attacked by free radicals. Those cells treated with EpiCor® showed decreased fluorescence intensity compared to control cells not treated with EpiCor®, verifying antioxidant activity in vitro.2
Numerous safety tests have been conducted on EpiCor®, revealing an extremely safe profile. Animal studies performed by a leading toxicology laboratory showed no indication of any toxic effects of EpiCor®. An acute oral toxicity study on 20 rats showed that the product was safe when given to rats at a single oral dose of 2000 milligrams per kilogram of body weight (equivalent to a human ingesting 280 capsules at once). After 2 weeks the rats showed no clinical symptoms, no deaths, no abnormalities in body weight, and no gross pathological changes. The same safety results were found in a subchronic toxicity study where rats were given up to 1500 milligrams daily for 90 days (equivalent to a human ingesting up to 210 capsules daily for 1.5 years). Again, absolutely no signs or symptoms of toxicity were noted in these animals.1,3
In addition, a standard bacterial reverse mutagenicity test (AMES test) as well as a mammalian cell mutation assay using mouse lymphoma cells revealed no evidence of any increase in mutation rates after exposure to EpiCor®. EpiCor® also showed no evidence of mitogenicity (inducing increased cell division) in a human lymphocyte proliferation assay. This suggests that EpiCor® does not cause over-reactivity of cells1,3.
The effect of EpiCor® on specific liver enzymes CYP1A2 and CYP3A4 (enzymes involved in metabolizing certain drugs and other compounds) was assessed. Immortalized hepatocytes (liver cells) were treated with various concentrations of EpiCor® and compared to both positive and negative controls. EpiCor® did not increase the expression or activity of the liver enzymes, suggesting that it may not affect the metabolism of other substances or medications metabolized by these enzymes if they are taken simultaneously. It also did not appear to be toxic to the cells as measured by lactate dehydrogenase assays and microscopic analysis.1
Lastly, EpiCor® was tested for safety in humans in an open label study on 15 adult men and women given a single 500 milligram dose for 30 days. On various days throughout the study vital signs were monitored, and blood and urine samples were analyzed. No clinically relevant abnormal effects on the participants were found1.
EpiCor® also currently has received self-affirmed Generally Regarded as Safe (GRAS) status by an expert panel that included eminent toxicologists1.
EpiCor® is a novel compound with an incredibly unique composition that has been shown to enhance immune system function.*
Suggested Adult Use: Take one capsule daily with or without food.
*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
1. Embria Health Sciences
2. Hart et al. A new Saccharomyces cerevisiae based product has anti-inflammatory effects while specifically activating human NK and B lymphocyte subsets. Unpublished study, personal communication.
3. Schauss AG, Jensen G, Vojdani A, Financsek I. After decades of ingestion by farm animals, the discovery of a yeast fermentate with unexpected significant immune modulatory activity when consumed by humans. [abstract] Journal of the
4. Schauss AG, Vodjani A. Discovery of an edible fermentation product with unusual immune enhancing properties in humans. [abstract] FASEB J, 2006; 20(4):A143.
5. Wu X, Beecher GR, Holden JM, Haytowitz DB, Gebhardt SE, Prior RL. Lipophilic and hydrophilic antioxidant capacities of common foods in the
December 17, 2005 10:40 AM
Date Sugar - Of the many alternatives to table sugar, the pleasant tasting extract of dehydrated dates may be one of the most natural and nutrient dense. While it can be used for a plethora of applications, the most common are in cereals, oatmeal, baked goods, beverages and puddings. In fact, date sugar bares a closer resemblance to food than it does to a sweetener. Nutritionally, it’s loaded with vitamins and minerals, especially potassium, magnesium, calcium, iron and phosphorus. Perhaps the most fascinating aspect of this natural sweetener is that it contain significant amounts of fiber. Best of all, date sugar is the closest in sweetness to the table sugar many have grown accustomed to.
HAWAIIAN NONI (Morinda citrifolia)
July 11, 2005 08:50 PM
In a time when we are more concerned than ever with issues of health, a tried and true tropical herb called noni needs t o be added t o our list of the best natural remedies. It susage over hundreds of years supports it s description as a veritable panacea of therapeutic actions. At this writing, noni continues to accrue impressive medicinal credentials, and its emergence as an effective nat ural healing agent is a timely one. Amidst rising cancer rates, the high incidence of degenerative diseases like diabetes, and the evolution of ant ibiotic resist ant bacteria and new viral strains, herbs like noni are sought after for their natural pharmaceutical properties. Unquest ionably, all of us want to know how to:
Indian Mulberry (India), Noni (Hawaii), Nono (Tahiti and Raratonga), Polynesian Bush Fruit, Painkiller Tree (Caribbean islands), Lada (Guam), Mengkudo (Malaysia), Nhau (Southeast Asia), Grand Morinda (Vietnam), Cheesefruit (Australia), Kura (Fiji), Bumbo (Africa) Note: This is only a small sampling of vernacular names for Morinda citrifolia. Almost every island nation of the South Pacific and Caribbean has a term for this particular plant . This booklet will refer to the herb mainly as “ noni” or M. citrifolia, and is referring primarily to Hawaiin noni.
The parts of the noni plant most used for their medicinal and nutritional purposes are the fruit, seeds, bark, leaves, and flowers. Virtually every part of the noni plant is utilized for its individual medicinal properties; however, it is the fruit portion that is regarded as its most valuable. The seeds have a purgative action, the leaves are used to treat external inflammations and relieve pain, the bark has strong astringent properties and can treat malaria, the root extracts lower blood pressure, the flower essences relieve eye inflammations and the f ruit has a number of medicinal actions.
Morinda citrifolia is technically an evergreen shrub or bush, which can grow to heights of fifteen to twenty feet . It has rigid, coarse branches which bear dark, oval, glossy leaves. Small white fragrant flowers bloom out of cluster-like pods which bear creamy-white colored fruit. The fruit is fleshy and gel-like when ripened, resembling a small breadf ruit . The flesh of the fruit is characterist ically bitter, and when completely ripe produces a rancid and very dist inctive odor. Noni has buoyant seeds that can float formont hs in ocean bodies. The wood of the inflammatory, astringent, emollient, emmenagogue, laxative, sedative, hypotensive (lowers blood pressure) , blood purif ier, and tonic.
Noni has various chemical constituents. First, it has an impressive array of terpene compounds, three of which—L. Asperuloside, aucubin, and glucose— have been identified by their actyl derivatives. Both caproic and caprylic acids have been isolated.1 Second, bushfruits, a category of which noni fruit is a member, are also considered a good source of vit - amin C.2 Third, Hawaiin noni has been linked to the synthesis of xeronine in the body which has significant and widespread health implications. Last , the alkaloid cont ent of the noni fruit is thought to be responsible for its therapeutic actions. Alkaloids exhibit a wide range of pharmacological and biological act ivitiesin the human body. They are nitrogencontaining organic compounds which can react with acids to form salts and which are the basis of many medicines. The following is an in-depth chemical analysis of each plant part and it s chemical constituents.
discovered an alkaloid in the Hawaiin noni fruit which he calls proxeronine and which he believes has appreciable physiological actions by acting as a precursor to xeronine, a very crucial compound (see later sections) . In addition, a compound found in the fruit called damnacanthol is believed to help inhibit cert ain viruses and cellular mutations involved in cancer.
ROOT AND ROOT BARK
Recent surveys have suggested that noni fruit exerts antibiotic action. In fact, a variety of compounds which have antibacterial properties (such as aucubin) have been identified in the fruit.5 The 6-Dglucopyranose pentaacet ate of the fruit extract is not considered bacteriostatic.6 Constituents found in the fruit portion have exhibited ant imicrobial action against Escherichia coli, Salmonella typhi (and other types) , Shigella paradysenteriae, and Staphylococcus aureaus. Compounds found in the root have the ability to reduce swollen mucous membrane and lower blood pressure in animal studies. Proxeronine is an alkaloid constituent found in Hawaiin noni fruit which may prompt the production of xeronine in the body. It is considered a xeronine precursor and was discovered in noni fruit by Dr. Ralph M. Heinicke. He has theorized that this proenzyme can be effective in initiating a series of beneficial cellular reactions through its involvement with the integrity of specific proteins. He points out that tissues contain cells which possess certain recept or sites for xeronine. Because the reactions that can occur are so varied, many different therapeutic actions can result when xeronine production escalates, explaining why Hawaiin noni is good for so many seemingly unrelated disorders. Damnacanthol is another compound contained in the fruit of the Hawaiin noni plant which has shown the ability to block or inhibit the cellular function of RAS cells, considered pre-cancerous cells.
Body Systems Targeted
The following body systems have all been effec-freeze-dried capsules, dehydrated powder or fruit, and oil. Noni plant constituents are sometimes offered in combination with other herbs. Some products contain a percent age of the fruit, bark, root and seeds for their individual therapeutic properties.
Extracts of M. citrifolia are considered safe if used as directed; however, pregnant or nursing mothers should consult their physicians before taking any supplement . High doses of root extracts may cause constipation. Taking noni supplements with coffee, alcohol or nicotine is not recommended.
Ideally, noni extracts should be taken on an empty stomach prior to meals. The process of digesting food can interfere with the medicinal value of the alkaloid compounds found in Hawaiin noni, especially in its fruit . Apparently, stomach acids and enzymes destroy the specific enzyme which frees up the xeronine compound. Take noni supplements without food, coffee, nicotine or alcohol. Using supplements that have been made from the semi-ripe or light - green fruit is also considered preferable to the ripe, whit ish fruit .
NONI: ITS USE AND HISTORY
Noni is a tropical wandering plant indigenous to areas of Australia, Malaysia and Polynesia. It is considered native to Southeast Asia although it grows from India to the eastern region of Polynesia. Morinda citrifolia has a long history of medicinal use throughout these areas. It is thought to be the “most widely and commonly used medicinal plant prior to the European era.” 7 Centuries ago, the bushfruit was introduced to native Hawaiians, who subsequently called it “noni” and considered its fruit and root as prized medicinal agents. Among all Polynesian botanical agents of the 19th and 20th centuries, Hawaiin noni has the widest array of medical applications. Samoan and Hawaiian medical practitioners used noni for bowel disorders (especially infant diarrhea, constipation, or intestinal parasites) , indigestion, skin inflammation, infection, mouth sores, fever, contusions and sprains. Hawaiians commonly prepared noni tonics designed to treat diabetes, stings, burns and fish poisoning.8 The herb’s remarkable ability to purge the intestinal tract and promote colon health was well known among older Hawaiian and Tahitian natives and folk healers. Interestingly, field observations regarding its repu-remarkable healing agent .
Wonder Herb of Island Folk Healers
Common to t he thickets and forests of Malaysia and Polynesia, and the low hilly regions of the Philippine islands, noni has been cultivated throughout communities in the South Pacific for hundreds of years. Its Hawaiian use is thought to originate from inter-island canoe travel and settlement dating to before Christ . Its hardy seeds have the ability to float which has also contributed to its distribution among various seacoasts in the South Pacific region. Historical investigation has established the fact that some of Hawaii’s earliest settlers probably came viaTahiti. For this reason, Tahitian herbal practices have specific bearing on the herbal therapeutics of islands to the nort h. The very obvious similarities between the Hawaiian vernacular for herbal plants like noni and Tahitian names strongly suggests the theory of Polynesian migrations to Hawaii. Cultures native to these regions favored using Morinda citrifolia for treating major diseases and ut ilized it as a source of nourishment in times of famine.9 Noni fruit has been recognized for centuries as an excellent source of nutrition. The peoples of Fiji, Samoa and Rarat onga use the fruit in both its raw and cooked forms.10 Traditionally, the fruit was propicked before it was fully ripe and placed in the sunlight . After being allowed to ripen, it was typically mashed and its juice extracted through a cloth. Noni leaves provided a veget able dish and their resiliency made them desirable as a fish wrap for cooking.
Noni’s Medical Reputation
Elaborate traditionalrituals and praying rites usually accompanied the administration of noni. Int erestingly, cultures indigenous to the Polynesian islands had a significant understanding of their flora. For example, native Hawaiians maint ained a folkmedicine taxonomy t hat was considered second to none.11 Noni was not only used for medicinal purposes but for its food value, for clot hing and for cloth dyes as well. Research indicates that noni was among the few herbal remedies that islanders considered “ tried and true.” In Hawaii, trained herbal practitioners reserved the right to prescribe plant therapies.12 Records indicate that Hawaiian medical practices were based on extensive and very meticulous descriptions of symptoms and their prescribed herbal treatments. Dosages were controlled and the collection and administration of plant extracts was carefully monitored.13 In addition to Morinda, it was not uncommon for these herbal doctors to also recommend using In regard to its application for common ailments, Hawaiians and other island communities traditionally prescribed noni to purge the bowel, reduce fever, cure respiratory infections such as asthma, ease skin inflammations, and heal bruises and sprains. In other words, noni was widely used and highly regarded as a botanical medicine.
A Timely Reemer gence
Today, the natural pharmaceutical actions of the chemical constituents contained in noni are scientif-ically emerging as valuable bot anical medicines. Tahitian “nono” intrigued medical practitioners decades ago; however, due to the eventual emergence of synthetic drugs, interest in this island botanical diminished until recent years. Ethnobot anists are once again rediscovering why Hawaiian people havet reasured and cultivat ed Morinda citrifolia for generations. Noni is now finding its way into western therapeutics and is referred to as “ the queen” of the genus Rubiaceae. Its ability to reduce joint inflammation and target the immune system have made it the focus of the modern scientific inquiry. Dr. Ralph Heinicke has conducted some fascinating studies on the chemical constituents of the Hawaiin noni fruit. His research centers on the proxeronine content of the fruit juice and how it profoundly influences human physiology. In addition, scientific studies investigating noni as an anti-cancer agent have been encouraging. It s conspicuous attributes and varied uses have elevat edits status to one of the best of the healing herbs. Today Morinda citrifolia is available in liquid, juice, freezedried capsules, or oil forms, and is considered one of nature’s most precious botanicals.
TRADITIONAL USES OF NONI
Throughout tropical regions, virtually every part of Morinda citrifolia was used to treat disease or injury. Its curative properties were well known and commonly employed. PatoaTama Benioni, a member of the Maoritribe from the Cook Islands and a lecturer on island plants explains: Traditionally Polynesians use noni for basically everything in the treatment of illness. Noni is a part of our lives. Any Polynesian boy will tell you he’s had exper ience with it . We use juice from its roots, its flowers, and its fruit... my grandmother taught me to use noni from the roots and the leaves to make medicine for external as well as internal use, and for all kinds of ailments, such as coughs, boils, diseases of the skin, and cuts.15
decoctions to stimulate delayed menst ruation.
XERONINE: THE SECRET OF NONI?
One informed professional on the subject of noni is Dr. Ralph Heinicke, a biochemist who has researched the active compounds of noni fruit for a number of years. He discovered that the Hawaiin noni fruit contains an alkaloid precursor to a very vital compound called xeronine. Wit hout xeronine, life would cease. In Dr. Heinicke’s view, noni fruit provides a safe and effective way to increase xeronine levels, which exert a crucial influence on cell health and protction. His research suggests that the juice from the M. citrifolia fruit contains what could technically be considered a precursor of xeronine—proxeronine. This compound initiates the release of xeronine in the intestinal tract after it comes in contact with a specific enzyme which is also contained in the fruit .
Because proteins and enzymes have so many varied roles within cell processes, the normalization of these proteins with noni supplemenation could initiate avery wide variety of body responses and treat many disease condit ions. Proteins are the most important catalysts found in the body. The beauty of obtaining a precursor to xeronine from the noni fruit is that the body naturally decides how much of this precursor to convert to xeronine. Disease, stress, anger, trauma and injury can lower xeronine levels in the body, thus creat ing a xeronine deficit . Supplementing the body with noni fruit is considered an excellent way to safely and naturally raise xeronine levels. It is the research and theories of Dr. Heinicke which have made the juice of the Hawaiin noni fruit a viable medicinal substance. He writes: Xeronine is analkaloid, a substance the body produces in order to activate enzymes so they can function properly. It also energizes and regulates the body. This par-ticular alkaloid has never been found because the body makes it, immediately uses it, and then breaks it down. At no time is there an appreciable, isolable amount in the blood. But xeronine is so basic to the functioning of proteins, we would die without it . Its absence can cause many kinds of illness.17 Because so many diseases result from an enzyme malfunction, Dr. Heinicke believes that using the noni fruit can result in an impressive array of curative applications. Interestingly, he believes that we manufacture proxeronine while we are sleeping. He proposes t hat if we could constantly supply our bodies wit h proxeronine from other sources, our need to sleep would diminish.18
How an herb is processed is crucial to how beneficial it is: this is especially true of noni, with its unique enzymes and alkaloids. Morinda citrifolia should be picked when the fruit is turning from its dark green immature color to its lighter green color, and certainly before it ripens to its white, almost translucent color. Once picked, noni, like aloe, will denature extremely quickly due to its very active enzymes. After harvesting, it should swiftly be flash frozen. This is similar to what is done to fish caught at sea to keep them f esh. This stops it from losing its potency while not damaging any of its constituents. To process noni, freeze-drying is recommended. This removes only the water without damaging any of this miracle plant’s vital enzymes and other phytonutrients like xeronine and proxeronine. This pure high-quality noni fruit juice powder is then encapsu-has a very harsh taste and an extremely foul smell, similar to the fruit it self . Other methods of processing include thermal processing, dehydrat ion and air drying. Thermal processing is generally found in liquids, while the dehydrat ed noni is then milled and encapsulated. Unfortunately both methods utilize high heat (110+°F) , which can deactivate many of the vital compounds that make noni so import ant . Air-drying is effect ive without using damaging heat but has serious quality control problems for commercial production.
MODERN APPLICATIONS OF NONI
Noni possesses a wide variety of medicinal properties which originat e from its differing plant component s. The fruit and leaves of the shrub exert antibacterial activities. Its roots promote the expulsion of mucus and the shrinkage of swollen membranes making it an ideal therapeutic for nasal congest ion, lung infect ions, and hemorrhoids. Noni root compounds have also shown natural sedative properties as well as the ability to lower blood pressure.
Leaf extracts are able to inhibit excessive blood flow or to inhibit the formation of blood clots. Noni is particularly useful for its ability to treat painful joint conditions and to resolve skin inflammations. Many people drink noni fruit extracts in juice form for hypert ension, painful menstruation, arthritis, gastric ulcers, diabetes, and depression. Recent studies suggest that its anticancer activit y should also be considered. Concerning the therapeutic potential of the Hawaiin noni fruit, Dr. Heinicke writes: I have seen the compound found in noni work wonders. When I was still investigating its possibilities, I had a friend who was a medical research scientist administer the proxeronine to a woman who had been comatose for three months. Two hour safter receiving the compound, she sat up in bed and asked where she was. . . . Noni is probably the best source of proxeronine that we have today.19 Studies and surveys combined support the ability of noni to act as an immunost imulant, inhibit the growth of certain tumors, enhance and normalize cellular function and boost tissue regeneration. It is considered a powerful blood purifier and contributor to overall homeostasis.
xeronine, which appears to be able to regulate the shape and integrity of cert in proteins that individually contribute to specific cellular activities. Interestingly, this effect seems to occur after ingestion, inferring that the most active compound of noni may not be present in uneaten forms of the fruit or other plant parts. Some practitioners believe that xeronine is best obtained from a noni fruit juice precursor compound. The enzymatic reactions that occur with taking the juice on an empty stomach are what Dr. Heinicke believes set cellular repair intomotion.
A study conducted in 1994 cited the anticancer activity of Morinda citrifolia against lung cancer. A team of scientists from the University of Hawaii used live laboratory mice to test the medicinal properties of the fruit against Lewis lung carcinomas which were artificially transferred to lung tissue. The mice that were left untreated died in nine to twelve days. However, giving noni juice in consistent daily doses significantly prolonged their life span. Almost half of these mice lived for more than fifty days.20 Research conclusions state that the chemical constituents of the juice acted indirectly by enhancing the ability of the immune system to deal with the invading malig-nancy by boosting macrophage or lymphocyte activit y. Furt her evaluation theorizes that the unique chemical constituents of Morinda citrifolia initiate enhanced T-cell activity, a reaction that may explain noni’s ability to treat a variety of infectious diseases. 21
In Japan, similar studies on tropical plant extracts found that damnacanthol, a compound found in Morinda citrifolia, is able to inhibit the function of KRAS- NRK cells, which are considered precursors to certain types of malignancies.22 The experiment involved adding noni plant extract to RAS cells and incubating them for a number of days. Observation disclosed that noni was able to significantly inhibit RAS cellular function. Among 500 plant extracts, Morinda citrifolia was determined to contain the most effective compounds against RAS cells. Its damnacanthol content was clinically described in 1993 as “a new inhibit or of RAS function.” 2 3 The xeronine fact or is also involved in that xeronine helps to normalize the way malignant cells behave. While they are still technically cancer cells, they no longer function as cells with unchecked growth. In time, the body’s immune system may be able to eradicate these cells.
with arthritic disease. One link to arthritic pain may be the inability to properly or completely digest proteins which can then form crystal-like deposits in the joints. The ability of noni fruit to enhance protein digestion through enhanced enzymatic function may help to eliminate this particular phenomenon. In addition, the alkaloid compounds and plant met abolites of noni may be linked to its apparent anti-inflammatory action. Plant sterols can assist in inhibiting the inflammatory response which causes swelling and pain. In addition, the antioxidant effect of noni may help to decrease free radical damage in joint cells, which can exacerbate discomfort and degeneration.
The alkaloid and other chemical compounds found in noni have proven themselves to effectively control or kill over six types of infectious bacterial strains including: Escherichia coli, salmonellatyphi (and other types) , shigella paradysenteriae, and staphylo - coccus aureaus.25 In addition, damnacanthol, was able to inhibitt he early antigen stage of the Epstein- Barr virus.
The bioactive components of the whole plant, combined or in separate portions, have demonst rat - ed the ability to inhibit several different strains of bacteria. Anecdotal reports support this action in that noni seems particularly effective in shortening the duration of certain types of infection. This may explain why noni is commonly used to treat colds and flu. The chemical constituents found in noni and the possibility that they stimulate xeronine production— as well as initiate alkaloid therapy—may explain noni’s reputation for having immuno-stimulatory properties. Alkaloids have been able to boost phagocytosis which is the process in which certain white blood cells called macrophages attack and literally digest infectious organisms. Interestingly, the ant it umoraction of noni has been ascribed to an immune system response which involves stimulating T-cells. tropical regions during World War II learned of the fruit’s ability to boost endurance and stamina. Native cultures in Samoa, Tahiti, Raratonga and Australia used the fruit in cooked and raw forms. M. citrifolia is considered a tonic and is especially recommended for debilitated conditions.
The process of aging bombards the body with free radicals which can cause all kinds of degenerative diseases. The xeronine theory promoted by Dr. Heinicke submit s t hat as our bodies age, we lose our ability to synthesize xeronine. To make matters worse, the presence of many environment altoxins actually blocks the production of xeronine as well. He believes that the proxeronine content of Hawaiin noni fruit juice can help to block these actions, thereby working as an antiaging compound.26 The phytonutrients found in noni assist in promot - ing cell nourishment and prot ect ion from free radicals created by exposure to pollution and other potentially damaging agents. In addition, Morinda citrifolia contains selenium, which is considered one of the best antioxidant compounds available.
While scientific studies are lacking in this particular application of noni, Hawaiians used various parts of the plant and its fruit to treat blood sugar disorders. Anecdotal surveys have found t hat noni is current ly recommended for anyone with diabetes.
A 1990 study found that extracts derived from the Morinda citrifolia root have the ability to kill pain in animal experiments.27 Interest ingly, it was during this study that the natural sedative action of the root was also noted. This study involved a French team of scientists who noted a significant central analgesic activity in laboratory mice.28 Dr. Heinicke has stated, “Xeronine also acts as a pain reliever. A man wit h very advanced int est inal cancer was given three months to live. He began taking the proxeronine and lived for a whole year, pain-free.” 29
Skin Healing Agent
One of the most prevalent hist rical uses of noni was in poultice form for cuts, wounds, abrasions, burns and bruises. Using its fruit extract for very serious burns has resulted in some extraordinary healing. Because skin is comprised of protein, it immediately responds to the presence of xeronine.
burn site throught he direct application of a noni poultice is considered quite effective by Dr. Heinicke and his colleagues, who have studied enzymatic therapy. Concerning burns, he has written: I believe that each tissue has cells which contain proteins which have receptor sites for the absorption of xeronine. Certain of these proteins are the inert for ms of enzymes which require absorbed xeronine to become active. This xeronine, by converting the body’s procol- langenase system into a specific protease, quickly and safely removes the dead tissue from burns.30
The xeronine link to treat ing drug addiction is based on the notion that flooding t he brain with extra xeronine can reverse the neurochemical basis for addiction. This natural alkaloid is thought to normalize brain receptors which subsequent ly results in the cessation of physiological dependence on a certain chemical like nicotine.3 1 The potential of Hawaiin noni as a natural stimulat or for t he production of xeronine may have profound implications in treating various types of addictions.
Complementary Agents of Noni
PrimaryApplications of Noni
Echinacea, Radiation and Chemotherapy
June 24, 2005 01:26 PM
Echinacea, Radiation and Chemotherapy
For anyone who has to undergo radiation treatments, echinacea can also be beneficial. One of the drawbacks of both radiation and chemotherapy is that white blood cells are destroyed by the treatments. The particular therapeutic action of echinacea discussed above shows that it can stimulate an increase in white blood cells following radiation treatments. These findings also suggest that echinacea works best to combat infection if taken early, before the infection spreads. In light of these studies, taking echinacea is highly recommended for anyone undergoing radiation or chemotherapy for cancer.
The Dual Immune Function of Echinacea
What is fascinating about echinacea is that while it can raise white blood cell activity it can also lower it when appropriate. This plant has the ability to affect opposite reactions in the body, and it is the body’s condition which determines they type of action initiated. There are no known synthetic drugs which have this dualism to both augment and suppress the immune response according to need. Laboratory tests have shown that echinacea does, in fact, boost the production of antibodies and T-cells. In the case of any infection, the sooner treatment is started, the better the results will be.
Interferon Production, T-Lymphocytes, and Echinacea
Interferon is produced in the body primarily by T-cells. The chemical components of interf e ron are extremely important in activating white blood cells to destroy cancer cells and viruses. Several nutrients can help boost the production of interferon but none seem to have the potency of echinacea. The effect of echinacea is considered remarkable in its ability to stimulate the production and action of interferon.8 It is this effect which results in significant antiviral actions T-Lymphocytes are responsible for what is called cell-mediated immunity. In other words, immune functions that are not controlled by antibodies. This type of immunity is vital in protecting the body against certain diseases caused by fungi (such as yeast infections), parasites, moldlike bacteria and viruses. Contracting these types of infections may indicate that the immune system has already been compromised and is susceptible to invasion. In addition to the disorders listed above, cell-mediated immunity also helps to protect us from autoimmune diseases such as arthritis, allergies and the formation of malignancies. Interferon is produced by T-Cells and acts to boost and potentiate the immune system. Laboratory tests have confirmed that extracts of the echinacea root contain interferon-like properties .9 Clearly, interferon boosts immune function and is currently being tested for its potential value in treating cancer. It is produced naturally in the body and enables body systems to resist viral invasion. Some studies have suggested that echinacea may be effective in fighting tumor related and infectious diseases.10 Echinacea has been found to effectively pre vent the spread of infection.11 It inhibits the production the action of hyaluronidase, an enzyme which is secreted by invading organisms to make surrounding tissue more susceptible to infection proliferation. Hyaluronic acid is the stuff that glues cells together to create tissue. It is vital to protecting our cell walls against the threat of invasion by disease microbes like strep and staph bacteria. Hyaluronidase breaks down the viscosity of this acid making it possible for organisms to enter and destroy. In addition, the polysaccharide contained in the herb can protect cells against diseases such as herpes, canker sores, colds, flu and a variety of infections.
The Lymph Sy stem and Echinacea
Echinacea acts as a natural antibiotic and helps to clear toxins from the glands and lymphatic systems. Lymphatic circulation is vital to the immune system. The lymph system is considered the second circulatory system of the body. It cleans the body of excess waste from cellular functions which is discarded through the kidneys. Lymphatic function can be improved by increasing the circulation of lymph fluid. Echinacea can accomplish this and in addition, helps to expedite waste products through the lymph system.12 Apparently, Echinacea improves the circulation of both blood and lymph, which can facilitate the removal of waste through the skin, kidneys and the bowel.
CLINICAL APPLICATIONS OF CAPSICUM
June 23, 2005 11:20 AM
CLINICAL APPLICATIONS OF CAPSICUM
Capsicum is a remarkable whole body stimulant that can boost blood flow, tone the nervous system, relieve indigestion, promote sweating, help to cauterize and heal ulcers, ease persistent pain and fight off infection. One very authoritative work on African plants suggests that Capsicum’s “regular ingestion is highly beneficial in hemorrhoids, varicose veins, anorexia, liver congestion and vascular conditions . . .the indigenous inhabitants of Africa and of the Antilles are remarkably free form all of these conditions as they use Capsicum fruit in their diet.”10 Most of the therapeutic actions of Capsicum are attributed to the alkaloid or glucoside content of the herb.11 The latest scientific studies conducted with Capsicum will be discussed in subsequent sections.
Because Capsicum boosts peripheral circulation and stimulates organ secretion, it expedites the therapeutic delivery and action of other herbs. In other words, the medicinal benefits of these herbs reach infected or inflamed tissue more rapidly due to enhanced blood flow.12 Consider the following statement: “Cayenne will insure the rapid and even distribution of the active principles of the rest of the herbs to critical function - al centers of the body, including those involved in cellular respiration, metabolism, data transmission, and neural-hormonal activation. Cayenne is included in several other blends for this reason. In extremely small quantities it can dramatically increase the efficiency of most other herbs.”13 Many health practitioners believe that the key to healing is CAPSICUM stimulation. Capsicum stimulates eve rything from blood flow to peristaltic action in the stomach, to intestinal transit time. The re m a rkable ability of Capsicum to stimulate organ secretion and even heart action makes it one of the strongest natural stimulants known. Se veral different kinds of herbal blends targeting various body systems will utilize Capsicum to boost the formula’s efficacy.
Capsicum is said to be unequaled for its ability to boost circulation and increase heart action. Interestingly, cultures who consume significant amounts of cayenne pepper in their diet have much lower rates of cardiovascular disease.14 Capsicum exerts a variety of desirable actions on the entire card i ovascular system. It has the extraordinary ability to enhance cardiovascular performance while actually lowering blood pressure.15 A quote taken from a card i ovascular publication re a d s , “Capsaicin has also been shown to prolong cardiac action potential in atrial muscle . . .”16 Michael T. Murray, N.D., has stated, “ Cayenne pepper [Capsicum] should be recommended as a food for its beneficial antioxidant and cardiovascular effects.”17 Herbalists have considered Capsicum as a superior “f o o d” for the heart. In fact, in cases where a heart attack is suspected administering capsicum in hot water has been thought to help lessen the severity of the attack. Capsicum can also be placed on or under the tongue in emergencies involving heart attack, stroke or hemorrhaging. 18 Note: Using Capsicum for any heart-related problem, especially a suspected heart attack should never take the place of medical attention or a physician’s care.
CAPSICUM Blood Cholesterol Reducer
Various studies have conclusively demonstrated that Capsicum reduces the risk of developing atherosclerosis (hardening of the a rteries) by reducing blood cholesterol and triglyceride levels .19 Additional clinical studies conducted in India found that when cayenne was ingested along with dietary cholesterol, the typical rise in liver and blood serum cholesterol levels was significantly inhibited. In addition, bile acids and free cholesterol were subsequently eliminated from the body through the stool.20 Interestingly, these tests revealed that using Capsicum was actually more effective in reducing cholesterol that capsaicin alone.2 1 Daniel Mowrey, Ph.D., emphatically points out that this is just one of many examples of the superiority of whole botanicals as opposed to their isolated components.22 Note: Using Capsicum in combination with Hawthorn is a particularly good cardiovascular tonic.
Blood Pressure Equalizer
While an added bonus of Capsicum’s capability to lower blood serum cholesterol is a decrease in blood pressure, additional evidence strongly suggests that the herb initiates other mechanisms that fight hypertension .23 “Cayenne, according to another study, also reduces the blood pressure in an even more direct manner: a number of years ago, a team of researchers discove red that capsaicin acts in a reflexive manner to reduce systemic blood pressure, a kind of coronary chemoreflex.”24 Adding Garlic to Capsicum creates an even better therapeutic blend for treating hypertension.
Blood Detoxification CAPSICUM
“Cayenne is a kind of catalyst in the blood purification process . . . it acts as a diaphoretic, stimulating the excretion of wastes in the swe a t . ”25 Because Capsicum stimulates organ secretion and boosts peripheral blood flow, it would only stand to reason that it would also facilitate the faster removal of toxins from the bloodstream and lymphatic system. You may have already noticed that Capsicum is frequently added to blood-purifying herbal combinations. Circulatory Booster Researchers have found that the simulating action of Capsicum on surface capillaries can help to pre vent cold hands and feet.2 6 For this reason, it may be helpful for Reynaud’s Syndrome. Old remedies using Capsicum have even recommended placing it in socks to warm the feet and to help prevent frostbite. An old folk cure for a chilled body was a steaming hot cup of Capsicum tea. Free Radical Scavenger The rich flavonoid content of Capsicum gives it significant antioxidant capabilities. A recent study conducted in 1995 showed that Capsicum has a higher ascorbic acid content than chiles from the jalapeno or serrano varieties .27 Vitamin C and bioflavonoids can scavenge for dangerous free radicals which cause tissue damage and can predispose organs to degenerative diseases. Free radicals are found everywhere and are created as by-products of metabolic p rocesses including the act of breathing itself. Pollutants can expose the body to free radicals. An interesting study done in Mexico City and published in 1993 found that Capsicum extract was able to modulate the mutagenic activity of urban air samples.28 In other words, these potentially dangerous nitro - a romatic compounds found in polluted air were kept from mutating by red chile extract.29 Chemical breakdowns of Capsicum have also found that CAPSICUM the pepper is high in Provitamin A, which significantly contributes to its healing ability and immune fortification.30 Anti-Carcinogenic Compound Anti-cancer research recently tested Capsicum on laboratory rats and found that it does indeed demonstrate anti-cancer properties by inhibiting certain enzymes which can initiate the mutation of cells.31 What this implies is that taking Capsicum can afford the body some protection against the cellular mutation which occurs in malignant growths. Capsicum actually inhibited the formation of dangerous metabolites under laboratory conditions where they should have normally been activa t e d .3 2 This study implies that Capsicum may have many more sophisticated bio-chemical actions than previously thought.
An Impressive Pain Killer
Capsaicin has recently emerged as a remarkably effective pain reliever and has become the subject of recent clinical research . Applying capsaicin in cream or ointment form to painful joints, scar tissue or other painful conditions involving peripheral nerves confuses pain transmitters. In other worlds, capsaicin temporarily disrupts sensory nerve cell biochemistry there by impeding the relay of pain sensations from the skin surface. It does this by inhibiting a neurotransmitter called substance P. This specific compound is thought to be the main mediator of pain impulses from peripheral nerve endings.33 Substance P has also demonstrated its ability to inhibit inflammatory pain generated in arthritic joints in much the same way.34 Today, several over-the-counter topical preparations utilize capsaicin for the pain of arthritic joints. The ability of Capsicum to control severe and unresponsive pain is significant, to say the least. Modern clinical utilization of topical capsaicin may offer signifi-cant relief for a number of painful conditions including: diabetic neuropathy, cluster headaches, post-amputation pain, post-mastectomy pain, shingles and painful scar tissue.35
In the early spring of 1996, prime time national news show s reported that scientists had found that individuals who had suffered from chronic pain in post-surgical scars (heart bypass, arterial grafts, etc.) were successfully treated with topical preparations containing capsaicin. While this may have been news to many of us, clinical studies had been already published for several years that capsaicin held profound value for various kinds of pain which did not respond to established medical treatments. Typically surgical scars and regions around them can produce persistent pain or can be very sensitive to the touch even when completely healed. This type of pain phenomenon seems to respond well to capsaicin ointments and creams.
When capsaicin preparations were applied following mastectomy or breast reconstruction, pain was significantly relieved. Se veral double blind studies found that using capsaicin creams four times daily for 4 to 6 weeks resulted in much less frequent occurrence of sharp, jabbing pain.3 6 All thirteen patients studied had a 50 percent or greater improve m e n t .3 7 Various unpleasant sensations other than pain also improved with topical applications of capsaicin creams.38
MOUTH SORES FROM RADIATION OR CHEMOTHERAPY
A fascinating study conducted at the Yale Pain Management Center discove red that capsaicin could ve ry significantly lessen pain caused by mouth sores which frequently develop after chemotherapy or radiation.39 Apparently delivering the capsaicin in the form of soft candy (taffy) enabled the substance to be retained in the mouth long enough to desensitize the nerve endings causing the pain. Each one of the eleven case studies re p o rted that their pain had decreased and in two patients, it stopped entirely.40
Diabetic neuropathy is a painful nerve condition which can develop in cases of prolonged diabetes. Several double-blind studies have supported the considerable value of capsaicin creams for relieving the pain associated with this disorder.41 The results of a controlled study using Capsicum for seve re cases of diabetic neuropathy which did not respond to conventional therapy were published in 1992. A cream containing Capsicum was applied to painful areas four time a day and pain was carefully e valuated for 8 weeks at two-week intervals. The results we re impressive, to say the least. In the 22 patients who used the Capsicum the following results we re re c o rded: “Capsaicin tre a tment was more beneficial than vehicle treatment in the overall clinical improvement of pain status, as measured by physician’s global evaluation and by a categorical pain severity scale . . . In a follow-up study, approximately 50 percent of the subjects reported improved pain control or were cured . . .”42 No t e : While there was a burning sensation when the Capsicum c ream was first applied, some subjects found that its magnitude and duration lessened with continued application.43
The FDA has approved capsaicin-based ointments for the treatment of pain that results from diseases like shingles. Again, numerous studies have documented the value of capsaicin for decreasing the miserable nerve-related pain associated with shingles. The general consensus derived from these tests were that approximately 50 p e rcent of people suffering from shingles responded well to capsaicin creams, some even after 10 to 12 months.44
Note: If blisters accompany a shingles outbreak, it is better to wait until they have healed before using any capsaicin-based ointments or creams.
RELIEF FOR BURNING FEET
Frequently an uncomfortable “burning” sensation in the feet will occur in many people, particularly in diabetics. As ironic as it may seem, using capsaicin creams may actually alleviate this burning. “In various studies, diabetics who treated their burning feet with capsaicin got greater improvement and we re able to walk more easily than those not using the cream.”45 In addition, using topical applications of capsaicin as opposed to strong, oral drugs is much more preferable.
Clinical tests have confirmed that topical capsaicin ointments substantially alleviate the miserable pain that characterizes osteoand rheumatoid arthritis.46 These studies revealed that using 0.075 capsaicin cream reduced tenderness and pain.47 Dr. Michael T. Murray writes: “ . . . seventy patients with osteoarthritis and thirty - one with rheumatoid arthritis received capsaicin or placebo for 4 weeks. The patients were instructed to apply 0.025 percent capsaicin cream or its placebo to painful knees four times daily. Significantly more relief of pain was reported by the capsaicin-treated patients than by the placebo patients throughout the study . . .”48 Anyone suffering from osteo or rheumatoid arthritis should evaluate the effectiveness of capsaicin ointments for joint pain. Ester Lipstein-Kresch, M.D., has studied the effectiveness of capsaicin creams for arthritis and has stated: “You need to apply it three or four times a day on the affected area for at least two weeks before you’ll see any improvement. An initial burning sensation at the site is not unusual for the first few days, but this goes away with continued application.”49 Note: Capsaicin is also useful for tennis elbow due to its ability to block the transmission of pain.
MIGRAINE HEADACHES (CLUSTER TYPE)
Topical applications of capsaicin ointments intranasally may also help to relieve the pain of a specific kind of migraine headache called cluster headaches. Cluster headaches are characterized by s e ve re pain which typically radiates around one eye. The term “cluster” refers to the fact that these headaches tend to occur in clusters of one to three per day and can recur at intervals. Headache pain and severity we re reducing in groups using intranasal capsaicin.5 0 This type of capsaicin treatment should be done under a physician’s care. There is some speculation that capsaicin may be more effective in pre venting migraines before they develop into a full blown attack.51
Pep Up and Go!
June 14, 2005 05:45 PM
Pep Up and Go!
by Harris Parker Energy Times, February 2, 2000
Feel your energy flagging?
You've lost count of the number of phone calls you fielded all afternoon-the last was from your son, who missed the late bus home from school-and colleagues needing your decision are lined up outside your office. Your husband has invited clients home for dinner. You wilt like a new hairdo on a damp August day and pray for a miracle to jump-start your engine.
Your pep quotient depends on three essential ingredients: nutrients you consume through your diet and supplements, how much you exercise and your sleep schedule.(Of course, if you're troubled by any kind of disabling, ceaseless fatigue accompanied by mental fuzziness, joint pain, sore throat, swollen glands, headaches and other chronic distress, consult your health practitioner.)
Vitamins and Energy
Certain nutrients are called vitamins because scientists consider them to be crucial for vitality. They generally function as coenzymes, partnering with the enzymes that are catalysts for the chemical reactions constantly taking place in our bodies. Our need to replenish our store of vitamins, which may merge with cell, muscle, enzyme, hormone, blood and bone structure once they have been absorbed, depends on their rate of utilization, according to The Real Vitamin & Mineral Book (Avery) by Shari Lieberman, PhD, and Nancy Bruning.
While a low-fat diet rich in raw fruits and vegetables helps supply important nutrients, a B complex supplement and a balanced multivitamin can guarantee daily vitamin levels.
Be Energetic with B Vitamins
Vitamins, especially the B vitamins, play extremely important roles in producing cellular energy. The chart on page 39 lists the key vitamins and describes their effects as well as the consequences of not getting enough of them. Their benefit is felt most profoundly in the energy producing process known as the Krebs cycle (which we'll explain in a moment).
Vitamins B2 and B3, for example, supply the major building blocks for substances that are called flavin adenine dinucleotide (FAD and FADH) and nicotinamide adenine dinucleotide (NAD and NADH), which are critical elements of energy production in the Krebs cycle as well as a process called oxidative phosphorylation.
Hundreds of Reactions
Even though you may never have heard of NAD and NADH, these molecules are found in very many places throughout your body; they play a role in hundreds of biochemical reactions in all kinds of cells. B vitamins also combine with other materials to build coenzymes, chemicals which help form other chemicals necessary for cellular energy. B vitamins are crucial: miss out on one or more and you may break these metabolic chains necessary for peak energy.
Energy to Spend
The main energy currency of every cell single cell is ATP: a chemical called adenosine triphosphate. This material is used by cells for every imaginable task including reproduction, growth, movement and metabolism. Specialized metabolic cycles within the cell are designed to generate ATP.
Consequently, the more ATP our cells create, the more energy can be generated. The raw materials used to make cellular energy are glucose (blood sugar) and "free" fatty acids. The best way to supply your cells with the sugar they need is to consume complex carbohydrates which also supply fiber and other nutrients. When you eat carbohydrates, they are made into glucose which is stored as a starch called glycogen in muscles and the liver. Your body can rapidly turn glycogen into glucose for extra energy. (The process of making energy from glycogen yields carbon dioxide and water as well as ATP.)
The first step in making glucose into energy is called glycolysis. This complicated process requires nine different steps. During these steps, glucose is made into a substance called pyruvate. The process of glycolysis requires ATP, but yields twice as much ATP as is present when it starts.
From here, the process gets a little more complicated as pyruvate enters into a complex chain of events in tiny cellular structures called mitochondria. (Many metabolic events take place in the mitochondria.) The pyruvate molecules are converted to a molecule known as acetyl coenzyme A and eventually made into carbon dioxide, water and more ATP.
This process is known as the Krebs cycle or citric acid cycle. It also involves a series of events known as oxidative phosphorylation in which NADH formed during the Krebs cycle is oxidized to form ATP.
Why is fat such a concentrated source of energy? Free fatty acids enter the Krebs cycle to help generate ATP much more efficiently than glucose - producing roughly six times more energy per gram than glucose.
And Don't Overlook. . . . . .other supplements that may aid energy production: • Alpha Lipoic Acid, an antioxidant that works in the fatty tissues of cell membranes and in cells' watery interiors • Coenzyme Q10, also known as ubiquinone as it exists everywhere in the body, acts like a vitamin because it stimulates some reactions. CoQ10 protects cell membranes, especially of the heart, against oxidation and toxins.
Ginsengs: Energy Generators
With their legendary and slightly mysterious characteristics, the ginsengs are greatly respected natural energy boosters. " Perhaps no herb has excited so much interest in medical circles as ginseng, and yet, strangely, it does not actually 'cure' any one particular ailment," reports Michael Hallowell, the author of Herbal Healing (Avery) and a frequent lecturer on botanic medicine. "Rather, its virtue lies in its tremendous power as a tonic and invigorator. Russian athletes are prescribed large amounts of ginseng because researchers in Moscow have shown that it not only improves stamina, but also increases the efficiency with which blood is pumped to the muscles."
What are the physiological mechanisms that allow ginseng to bolster your get up and go? In order to unravel the legend and lore of ginseng, the first step is understanding the intricacies of the three types: • Asian (Panax ginseng), which produces the strongest and most profound stimulation; • American (Panax quinquefolium), which soothes at a more subtle level; • Siberian (Eleutherococcus senticosus), a stamina booster embraced by a wide range of athletes. All three varieties are treasured for their ability to help people adjust to stress.
The ginsengs are adaptogens, "biologically active substances found in certain herbs and plants that help the body and mind adapt to the changes and stress of life," says Stephen Fulder, MD, author of The Book of Ginseng and Other Chinese Herbs for Vitality (Inner Traditions). "Stress is not an illness in itself. Stress is change, our ability to adapt to all the changes that occur in life, emotional or physical, from exercise, work, chemicals, drugs, food, radiation, bacteria, disease, temperature, or simply too many late nights or too much fun."
The body reacts to stress by producing the hormone adrenaline, which throws the whole body into a state of alert. Metabolism, blood pressure and circulation accelerate; immunity and resistance drastically decline; performance suffers.
Enter the ginsengs, with their varied, subtle tonic qualities. The Greek name for this herb, "panax," means "panacea" or cure-all. But the Chinese, who first referred to it 2,000 years ago, more literally called it "ren shen" or "person root," in reference to its physical resemblance to a miniature human form.
" Most exhibit medicinal properties, but each species has a different chemical makeup and has a unique application in Traditional Chinese Medicine (TCM)," says Kim Derek Pritts, author of Ginseng: How to Find, Grow and Use America's Forest Gold (Stackpole). "In general, all true ginseng contains biologically active saponins (chemicals similar to human hormones), essential oils, carbohydrates, sugars, organic acids, nitrogenous substances, amino acids, peptides, vitamins and minerals."
Building Vital Energy
All the ginsengs strengthen, nourish and build Qi, the TCM concept describing basic vital energy circulating through our bodies. Every physical and mental function, from breathing, thinking, nutrition and circulation, is regulated by Qi. Although many of the Native American tribes used the abundant, indigenous Panax quinquefolium ginseng extensively, particularly to increase mental acuity and boost fertility, the herb never has been as popular in North America as it is in Asia. American ginseng traditionally has been a lucrative export crop to China, where the wild native variety suffers from overharvesting. Even today, according to Paul Bergner in The Healing Power of Ginseng & the Tonic Herbs (Prima), 95% of the American ginseng crop is exported to China, where XiYang Shen, or "western sea root," as it is called, is immensely valued and costs double what it does here.
Jacques MoraMarco, author of The Complete Ginseng Handbook: A Practical Guide for Energy, Health and Longevity (Contemporary), as well as a licensed acupuncturist and doctor of Eastern medicine, suggests American ginseng for a slight energy boost. The moderate effect of American ginseng is considered a more appropriate tonic to the intensity of our pace and diet.
Variations on a Theme
In TCM terms, American ginseng cools and moistens, as well as lubricates and strengthens the body. It is reputed to reduce fevers and night sweats and alleviate hot, dry lung problems like smoker's cough. With its emollient qualities, American ginseng is considered to treat dry, wrinkled skin effectively.
The Bolder Energizer
Asian ginseng, which includes red Korean panax, is a bolder energizer taken by those who feel depleted from anemia, blood loss, cardiovascular weakness, injury, shock or trauma, as well as the disabling effects of age. In general, Asian ginseng is warming and stimulating, urging the body to run faster.
Siberian ginseng, though botanically not a true ginseng, still acts similarly to Asian ginseng in its reputed power to control stress, boost energy, support the immune system, enhance performance and increase longevity. Called Wu Cha Seng in Chinese, Siberian ginseng is perceived by natural practitioners as an ideal herb for the healthy who want to lift both stamina and endurance. Experts believe it counteracts the effects of cortisol, the stress hormone produced by the adrenal glands in response to injury, pain or emotional turmoil.
Natural Energy Boosters
The herbal pharmacopeia includes several other natural energy boosters available in various forms-shakes and bars for those on the run-loaded with nutrition absent from commercial snacks. Some choices: • Ginkgo biloba-used in Chinese medicine to heat the body and increase sexual energy. Ginkgo enthusiasts take this herb to increase the supply of oxygen to the brain and generally increase circulation. • Gotu kola-may stimulate the central nervous system and help eliminate excess fluid, thereby reducing fatigue. • Astragalus-a Chinese herb that enhances energy and builds the immune system. It is credited with strengthening digestion, improving metabolism, increasing appetite, combating diarrhea and healing sores. • Schisandra-also a Chinese herb, treats respiratory illness, insomnia and irritability and rejuvenates sexual energy. Its mild adaptogens help the body to handle stress. • Licorice-is a favored endocrine toner in Chinese medicine. It is reputed to support the adrenals, the pair of small glands directly above the kidneys that secrete steroidal hormones, norepinephrine and epinephrine, the "fight or flight" hormones. People with high blood pressure or edema, or pregnant women, should avoid it. • Ashwagandha-an Ayurvedic herb used for thousands of years in the traditional healing of India as a potent strength builder for men and women.
Experienced herbal practitioners acquire an impressive and fascinating store of knowledge and experience-you'll find it helpful to visit one as you begin your course of ginseng or other energy-boosting herbs.
When you visit a TCM practitioner, you'll notice that she evaluates your body's condition through an extremely careful examination of all the different systems: Several pulse points are felt in order to ferret out and detect troubling abnormalities. The condition and color of the tongue is observed to decipher digestive disorders. In addition, your urine may be examined to determine other imbalances and specific health problems.
In many cases, your TCM practitioner will recommend ginseng as an adaptogen that can give you an overall boost. When taking ginseng, follow the directions on the package. Note: in some cases, you may want to consume a little bit less if you suffer headaches, insomnia or high blood pressure. Consult your health practitioner if you are afflicted with either acute inflammatory disease or bronchitis.
Then take comfort in the eternal soothing wisdom of Chinese Traditional Medicine. In the first century A.D., the Shen Nong Ben Cao Jing (The Divine Husbandman's Classic of the Materia Medica) effusively described ginseng and the tonic herbs in this beguiling and intriguing manner: "The first class of drugs...are considered to perform the work of sovereigns. They support human life and they resemble heaven. They are not poisonous regardless of the quality and duration of administration."
America's Most Wanted
June 14, 2005 05:23 PM
America's Most Wanted
by Brian Amherst Energy Times, January 6, 2000
The United States eats well, a little too well, according to experts. Amply supplied with a large supply of high-calorie food, our diets might seem to be chock full of every conceivable nutrient. Well, to the question "Getting all the right vitamins, minerals and other nutrients?" the most appropriate answer seems to be "Not exactly." Eating a lot doesn't equal eating a lot of the most important vitamins and minerals. So, which vitamins and minerals are likely to show up in short supply in the typical American diet? Calcium certainly sits at the top of list. According to the most recent Continuing Survey of Food Intake by Individuals, which is conducted by the United States Department of Agriculture (USDA), women and girls age 12 and up are not consuming adequate calcium from their diet. Research reveals that about 1200 mg. day suffices for those over age 50 and 1000 mg a day should be adequate if you're between the ages of 19 and 50. Since strong bones are formed during "the first three decades of life," says Laura Bachrach, MD, of Since strong bones are formed during "the first three decades of life," says Laura Bachrach, MD, of Stanford University, ". . .osteoporosis is a pediatric disease." For long-range protection against that bone-weakening disease, kids should eat calcium-rich, low-fat dairy products and plenty of leafy greens (broccoli, cabbage, kale) as well as salmon (with bones), seafood and soy. But the calcium campaign does not end in early adulthood. Bone mass begins to deteriorate at about age 30. Menopausal hormonal changes can exacerbate bone brittleness. Medical conditions, including cancer, liver disease and intestinal disorders; prescription drugs; tobacco and alcohol indulgence; or a decline in activity, especially the weight-bearing kind, also jeopardize bone strength. According to the National Osteoporosis Foundation, about one in every two American women will break a bone after age 50 due to osteoporosis. That translates into about half a million fractured vertebrae and more than 300,000 shattered hips. Frequently, those breaks are life-threatening.
The critical role of calcium in many body functions is perhaps the most extensively clinically documented among nutrients. Researchers in the Department of Medicine, Oregon Health Sciences University in Portland, reviewed epidemiological and clinical studies conducted over the past two years on the relationship between dietary calcium and blood pressure (J Am Coll Nutr October 1999: 398S-405S). "Nearly 20 years of investigation in this area has culminated in remarkable and compelling agreement in the data," the researchers report, "confirming the need for and benefit of regular consumption of the recommended daily levels of dietary calcium." Investigators at the State University of New York, Buffalo School of Dental Medicine, presented results of their studies of calcium and vitamin C and gum disease at the June 26, 1998 meeting of the International Association for Dental Research. Two separate inquiries revealed that people who consumed too little calcium as young adults, and those with low levels of vitamin C in their diets, appear to have nearly twice the risk of developing periodontal disease later in life than folks with higher dietary levels of either nutrient.
Calcium: Much Documented Researchers offer extensive evidence of calcium's benefits on many fronts: n Osteoporosis poses a threat to older men as well as women, according to Randi L. Wolf, PhD, research associate at the University of Pittsburgh Graduate School of Public Health. Dr. Wolf presented her award-winning study to an October 3, 1999 meeting of the American Society for Bone and Mineral Research. Dr. Wolf suggests that men increase their consumption of calcium, particularly after age 80, to avoid age-related declines in the amount of calcium absorbed. According to Dr. Wolf, "It appears that the hormonal form of vitamin D, which is the main regulator of intestinal calcium absorption, may have an important role. We are conducting more research to better understand the reasons for why calcium absorption declines with age in men." n Scientists at Tufts University in Boston did some earlier work on the calcium-vitamin D connection and reported it in the September 4, 1997 New England Journal of Medicine. Using the National Academy of Sciences (NAS) increased recommended daily intake of 1200 milligrams of calcium and 400 to 600 international units of vitamin D for people over 50, the Tufts researchers found that with supplementation of the nutrients, men and women 65 and older lost significantly less body bone and, in some cases, gained bone mineral density. n Two studies published in American Heart Association journals show that atherosclerosis and osteoporosis may be linked by a common problem in the way the body uses calcium. The September 1997 Stroke revealed that, in a group of 30 postmenopausal women 67 to 85 years old, bone mineral density declined as atherosclerotic plaque increased. Researchers reporting in Circulation (September 15, 1997) advanced the theory that the osteoporosis-atherosclerosis connection may be related to a problem in handling calcium. n For people who had colon polyps removed, taking calcium supplements decreased the number of new polyps by 24% and cut the risk of recurrence by 19%, according to researchers at the University of North Carolina, Chapel Hill, School of Medicine. The study, published in the January 14, 1999 New England Journal of Medicine, was a first in crediting calcium with anti-cancer properties.
The D Factor
Without adequate vitamin D, your absorption of calcium slips and bone loss can accelerate, increasing the risk for fractures. Fifty percent of women with osteoporosis hospitalized for hip fractures at Brigham and Women's Hospital in Boston had a previously undetected vitamin D deficiency (Journal of the American Medical Association, April 28, 1999). University of Pittsburgh Cancer Institute researchers told participants at the April 14, 1997 meeting of the American Association for Cancer Research that vitamin D "significantly inhibits highly metastatic, or widespread, prostate cancer in animals," suggesting its potential for treating men with similar conditions. Few foods that Americans eat, except dairy, contain much vitamin D, but we can usually synthesize sufficient amounts from as few as five minutes' exposure to the sun. But as skin ages, its ability to act as a vitamin D factory decreases. According to Michael F. Holick, the director of the Vitamin D, Skin and Bone Research Laboratory at Boston University Medical Center, upwards of 40% of the adult population over age 50 that he sees in his clinic are deficient in vitamin D. Recently, the National Academy of Sciences (the official body that decrees the required amounts of necessary nutrients) increased the daily recommendations of vitamin D to 600 IU for people over 71, 400 IU for those aged 51 to 70 and 200 IU for people under 50. The best dietary sources, apart from dependable supplements, are dairy and fatty fish like salmon. Four ounces of salmon provide about 300 IU.
The Facts About Fats
The American lust for low-fat, high-carbohydrate diets filled with sugary foods has exploded into nothing short of "obsession," according to experts at the General Research Center at Stanford University Medical Center (Am J Clin Nutr 70, 1999: 512S-5S). That mania oftens robs us of the crucial balance of omega-3 and omega-6 fatty acids typical of the Mediterranean diet that protect us from heart disease by controlling cholesterol and making blood less likely to form clots. These fatty acids cannot be made by the body but are critical for health: n Omega-3 fatty acid (linolenic acid) comes from fresh, deepwater fish (salmon, mackerel, sardines) and vegetable oils such as canola, flaxseed and walnut. n Omega-6 fatty acid (linoleic acid) found primarily in raw nuts, seeds and legumes and in saturated vegetable oils such as borage, grape seed, primrose, sesame and soybean. The American Heart Association recommends limiting total fat consumption to 30% of daily calories. Saturated fats like those in dairy and meat products as well as vegetable oil should comprise 10% of total calories; total unsaturated fat (fish oils, soybean, safflower nuts and nut oils) should be restricted to 20 to 22% of daily calories.
Be Sure About B12
Vitamin B12 presents a particular problem for the elderly because older digestive systems often don't secrete enough stomach acid to liberate this nutrient from food. (The elderly have no problem absorbing B12 from supplements, because it's not bound to food.) Vitamins generally moderate the aging process but, ironically, that process and the diseases that frequently accompany it affect vitamin metabolism (Schweiz Rundsch Med Prax 83, 1994: 262-6). And because of those changes, we need more of certain vitamins. This is the case for vitamins D, B6, riboflavin and B12. Crucial for health, B12 is necessary to prevent anemia, and, according to recent studies, needed (along with folate and B6) to help stave off heart disease. B12, with thiamine and niacin, boosts cognition (Adv Nutr Res 7, 1985: 71-100). Screening for vitamin B12 deficiency and thyroid disease is cheap and easy and can prevent conditions such as dementia, depression or irreversible tissue damage (Lakartidningen 94, 1997: 4329-32). In the January 5-12, 1999 issue of Circulation: Journal of the American Heart Association, the AHA urged doctors to screen levels of homocysteine (the amino acid byproduct of protein digestion that damages arteries, causes heart disease and, possibly, strokes) in patients at high risk for heart disease. They also recommended all Americans to up their daily levels of vitamins B6 and B12, as well as folic acid. Since fruits, vegetables or grains lack B12, vegetarians need B12 supplements. And they're a good idea for the rest of us, too.
Folic Acid Benefits
Folic acid made headlines in the early 1990s when the U.S. Public Health Service declared that "to reduce the frequency of neural tube defects [spina bifida, or open spine, and anencephaly, a lethal defect of the brain and skull] and their resulting disability, all women of childbearing age in the United States who are capable of becoming pregnant should consume .4 milligrams (400 micrograms) of folic acid per day." This recommendation followed voluminous research that showed taking folic acid was associated with a significantly reduced risk of birth defects. (The advisory is based on the fact that nearly half of all pregnancies are unplanned. If you think you are pregnant, consult your health practitioner for supplementary advice.)
A Team Player
Folic acid's efficacy intensifies when it works with other nutrients. Among many studies on the preventive powers of folic acid on birth defects, one published in The New England Journal of Medicine (327, Dec. 24, 1992: 1,832-1,835), disclosed an even greater decrease in neural tube defects when supplements of folic acid contained copper, manganese, zinc and vitamin C. As a warrior against homocysteine, folic acid joins the battalion of B12 and B6 in detoxifying this harmful protein. At the University of Washington's Northwest Prevention Effectiveness Center, researchers recently analyzed 38 published studies of the relationship between folic acid, homocysteine and cardiovascular disease and, according to associate professor Shirley A. Beresford, MD, folic acid and vitamin B12 and B6 deficiencies can lead to a buildup of homocysteine.
Canadian researchers reported in the Journal of the American Medical Association (275, 1996: 1893-1896) that men and women with low folic acid have a 69% increase in the risk of fatal coronary heart disease. This 15-year study of more than 5,000 people stressed the need for dietary supplementation of folic acid. Folic acid also has been credited with the potential to protect against cancers of the lungs, colon and cervix. It appears to help reverse cervical dysplasia, the precursor cells to cervical cancer, especially for women taking oral contraceptives, which may cause a localized deficiency of folic acid in the cells of the cervix. According to Shari Lieberman, PhD, and Nancy Bruning, authors of The Real Vitamin & Mineral Book (Avery), folic acid derivatives work with neurotransmitters, the chemicals that permit signals to be sent from nerve fiber to nerve fiber. A lack of folic acid can cause some nervous-system disorders, such as depression, schizophrenia and dementia; it also may be related to some forms of mental retardation. Other supporting roles of folic acid, according to researchers: the formation of normal red blood cells, important for preventing the type of anemia characterized by oversized red blood cells; strengthening and improving white blood cell action against disease; limiting production of uric acid, the cause of gout.
The Best Sources
Many foods are rich in folic acid: beef, lamb, pork and chicken liver, spinach, kale and beet greens, asparagus, broccoli, whole wheat and brewer's yeast. But experts believe that only 25 to 50% of the folic acid in food is bioavailable. Processing also reduces an estimated 50 to 90% of its content. Folic acid supplementation overcomes these obstacles with little risk, as it has no known toxicity. Women taking folic acid who are current or former users of oral contraceptives may require additional zinc. And be sure to augment your folic acid supplement with its synergistic counterpart, vitamin B12.
Focus on Fiber
The American Heart Association came out squarely behind fiber in a June 16, 1997 issue of its journal Circulation: Double your daily intake to lower cholesterol and the risk of heart disease. The American diet is consistently low in fiber, notes Linda Van Horn, PhD, RD, author of the article. Twenty-five to 30 grams a day from foods (or supplements) are not only heart healthy but seem to aid weight control.
Getting enough iron? An estimated 25% of adolescent girls in the United States are iron deficient, according to an October 12, 1996 issue of the British medical journal The Lancet, which reported that girls who took iron supplements performed significantly better on verbal tests than those who took a placebo. "Teenage girls should be regularly tested for iron deficiency because rapid growth and the onset of menstruation during puberty increase the body's need for iron," says Ann Bruner, MD, of the Johns Hopkins Children's Center and a lead author of the study.USDA data reveal that women up to age 50 also tend to get much less than recommended levels of iron, a lack of which leads to anemia, a deficiency of red blood cells, hemoglobin or volume of blood. For kids, deficiency is more common from six months to four years and during the rapid growth spurts of adolescence when the body is growing so quickly that the body's iron stores may sink to dangerous levels. Vegetarian women run the greatest risk for deficiency, as meat is iron-rich; foods like beans, grains and vegetables also contain some iron. Supplements, of course, supply easily absorbable iron. And to absorb iron from vegetarian sources, take vitamin C with your meals. That boosts the amount of this mineral you will take in. Bear in mind, however, that certain folks-older men and post-menopausal women-generally have adequate dietary supplies of iron. Of greater concern, in fact, is excessive iron, and for these folks iron-free multivitamin and mineral supplements are available.
Ante Up the Antioxidants
Antioxidant nutrients help protect the body from oxygen-scavenging molecules called free radicals. The products of pollution, the body's own metabolic processes and other sources, free radicals are linked to heart disease, cancer and other chronic health problems. The most important antioxidants, which include vitamin C, E, beta carotene, and selenium, are often lacking in the American diet. Plus, optimal amounts of vitamin E cannot be consumed from food. You need supplements. The bottom line: even though we live in a land of plenty, you can still miss vital nutrients. So make sure to consume these vital substances.
Source of Missing Nutrients In the search for the nutrients missing from America's diet, one big help is the sprout. The sprout is truly one of nature's heavyweights: fresh, tiny and moist, its power punch of vitamins, minerals, protein, chlorophyll and disease-busting phytochemicals land it in a weight class far beyond that of its full-grown competitors. Size does NOT matter to this nutritional giant. A championship belt currently wraps around the miniscule broccoli sprout, catapulted into the ring by Paul Talalay, MD, professor of pharmacology and molecular sciences at Johns Hopkins University. Dr. Talalay discovered that the seedlings contain substantially more of the cancer-fighting substance sulforaphane than mature plants (Proc. Natnl. Acad. Sci. USA, 94, 10367-10372). Sprouts, the quintessential health food of the Sixties, provide a wonderfully varied and versatile way to get your daily greens. Raw or cooked, strong or mild, vegetable and grass sprouts and their algae cousins add low-calorie texture to recipes and a rich, diverse complement of nutrients and fiber.
Ancient Asia to the Modern Lab
Asians stir-fried sprouts as one of the earliest fast foods as long as 5,000 years ago. The ancient Chinese relied on sprouts for year-round vegetables in colder regions of their vast country. Today, researchers studying sprouts and adult plants have identified their important chemoprotective and other health-bolstering substances. In Paul Talalay's research project at Johns Hopkins, scientists found that three-day-old broccoli sprouts contain up to 50 times more sulforaphane than mature plants, which prompts the body to produce an enzyme that prevents cancer tumors from forming. Uniform levels of the compound saturate the shoots, unlike the chemically uneven adult plants. The Brassica family of broccoli and cabbage is richly endowed with phytochemicals that also help reduce estrogen levels associated with breast cancer. Other phytochemical compounds in the Brassica family are associated with the prevention of stomach and lung cancers. Most of the initial landmark work on phytochemicals' cancer-fighting powers has taken place since 1989 under the aegis of the National Cancer Institute's "Designer Food Program," which isolated, for example, the isoflavones in beans that seem to neutralize cancer-gene enzymes.
Strong Suit: Soy and Spirulina
The isoflavones and phytosterols in soy produce an estrogenic effect that appears to relieve menopausal symptoms and help prevent breast cancer. Soy foods expert Mark Messina, PhD, has done extensive work on the subject, some of which has been published in the Journal of the National Cancer Institute 83, 1991: 541-6. Researchers also have synthesized a bone-strengthening form of soy isoflavones called ipriflavone, following impressive clinical trials in the treatment of osteoporosis (American Journal of Medicine, 95 [Suppl. 5A] (1993): 69S-74S). Spirulina and other micro-algae are fascinating organisms that inhabit a niche between the plant and animals kingdoms. Named for its tiny spirals, spirulina, a blue-green algae, grows in saline lakes but is cultured for maximum nutritional content. In her book Whole Foods Companion (Chelsea Green), Dianne Onstad notes that spirulina contains "the highest sources of protein, beta carotene and nucleic acids of any animal or plant food." Its nucleic acids, she says, benefit cellular regeneration; its fatty acids, especially GLA and omega-3 acids, make it one of the most complete foods. Sprouts, like any other produce, should be rinsed thoroughly before serving. People at high risk for bacterial illness-young children, the very elderly or folks with weakened immune systems-should limit their consumption of raw sprouts. But no matter how you eat them, you may find more spring in your step from these tiny, sprouting nutritional wonders.
Mushroom Immune Defense - Scientific Immunity Formula
June 04, 2005 10:08 AM
The immune system is a fascinating and complex group of cells and biochemical processes. Its many components work to protect you from environmental threats—but your immune system requires nutritional support to function optimally. Scientific research is proving that some of the most powerful immune-supportive nutrients are found in mushrooms. People who realize the critical importance of optimizing immune function should seriously consider adding an advanced mushroom complex to their daily regimen. No other mushroom formula offers the high-potency, broad-spectrum benefits of Source Naturals MUSHROOM IMMUNE DEFENSE. MUSHROOM IMMUNE DEFENSE features 16 of the best-studied species of health-supportive mushrooms, including shiitake, reishi, and maitake. These mushrooms contain compounds, including beta-glucans, glycoproteins and polysaccharides, that support a wide range of immune defenses: natural killer cell, T-cell and macrophage activity, and cytokine production. By combining a wide variety of mushrooms and fortifying them with extracts to ensure high potency, MUSHROOM IMMUNE DEFENSE offers a biochemically diverse formula that provides optimum immune assistance.
How Do Mushrooms Work?
Mushrooms are a treasure trove of bioactive compounds, but most of their immunomodulating activities have been attributed to polysaccharides (long-chain, simple sugars) and glycoproteins (polysaccharides naturally associated with proteins). These compounds activate a variety of immune responses.
MUSHROOM IMMUNE DEFENSE contains mycelia (networks of fibrous filaments) and extracts from the widest variety of mushroom species available. Included are the following mushrooms, which have demonstrated the most evidence for immune defense. Shiitake (Lentinula edodes): Lentinan, the beta glucan from shiitake, has been studied more extensively than similar substances and may be one of the most effective immunomodulators. Numerous studies have shown its ability to stimulate natural killer cell, T-cell, and macrophage-dependent responses.
Reishi (Ganoderma lucidum): Reishi’s polysaccharides may stimulate macrophages and enhance T-cell proliferation, according to in vitro studies.
Maitake (Grifola frondosa): Maitake enhances the activities of natural killer cells, T-cells and macrophages, according to animal studies. MUSHROOM IMMUNE DEFENSE contains MaitakeGold 404™, a highly specialized maitake product, rich in beta-glucans, which is the only maitake betaglucan fraction endorsed by the world’s premier maitake researcher, Dr. Hiroaki Nanba, Ph.D. Turkey Tails (Trametes versicolor): These mushrooms have a long history of traditional use in Asia. One in vitro study suggests that its polysaccharides stimulate macrophages.
Almond portabella (Agaricus blazei): This mushroom may stimulate the immune system by increasing T-cell activity, according to animal studies.
Cordyceps (Cordyceps sinensis): Cordyceps came to international attention during National Games in China when, in one week, three women’s track and field world records were broken. The coach partially credited a cordyceps elixir. Cordyceps was found to augment antibody and other immune responses in one animal study, and a cordyceps polysaccharide was found to elevate cytokines in vitro.
MUSHROOM IMMUNE DEFENSE contains 10 additional mushrooms, including enoke, oyster, Polyporus umbellatus, and Poria cocos. Vitamin C is added to enhance absorption and activity.
Unparalleled Immune Support
A focus on immune support can pay tremendous dividends for your entire life. If you are dedicated to good health, you want a powerful formula on your side. Source Naturals is proud to join forces with your natural foods retailer to bring you an unparalleled immune formula: MUSHROOM IMMUNE DEFENSE.