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Omega-3 Deficiency Symptoms + 3 Steps to Overcome Them
February 28, 2019 08:47 AM
Omega-3s have a wide variety of benefits for your brain and cardiac health, as well as keeping inflammation in check and hormones in balance, so you definitely shouldn’t let yourself become deficient. Omega-3s are an essential fatty acid, meaning the body cannot produce them on its own. A deficiency can cause inflammation, digestive troubles, and pain in muscles and joints, as well as changes in the appearance of skin and hair. Deficiencies can also cause or worsen ADHD symptoms or depression. A lack of omega-3s can even result in poor brain development in children and neurodegenerative symptoms in adults.
"“Omega-3s” is another name for omega-3 fatty acids. These fats are found in the human body, as well as in certain foods like oily fish. Essential fatty acids are “essential” because the body cannot synthesize them on its own, therefore humans must get these fats from the diet."
Read more: https://draxe.com/omega-3-deficiency/
What's the Best Sleep Position for Your Health?
May 21, 2018 01:16 PM
Sleeping on your left side is considered the most advantageous sleeping position due to the fact that it allows toxins and excess fluids to be removed from your body more easily. Other positions such as sleeping on your right side and sleeping on your back can also be beneficial but to a lesser extent. Sleeping either on your stomach or in a fetal position would rate as the least advantageous sleeping positions for several reasons including the strain each of those positions puts on your back.https://www.youtube.com/watch?v=blrAwlhoRrU&rel=0
Did You Know That Folic Acid Can Help Prevent Birth Defects
There is continuing good press for folic acid in several aspects of human health, but the foremost health issue it addresses is a human reproduction. The popular belief that folic acid removes serious birth defects is supported by incontrovertible scientific facts. If a woman plans on getting pregnant, eating foods rich in folic acid is among other things that have to take priority.
Folate is an indispensable component of life in that it is directly connected to DNA and RNA processes, most notably in inhibiting changes to DNA. Folate deficiency results in the limited production of cells such as erythrocytes, also called red blood cells, bringing about abnormalities of cells in the body.
The fact that folate sustains the enhanced rate of cell division promotes the correct developments of body tissues and organs during pregnancy, significantly reducing the number of reported congenital malformations. Folate stabilizes DNA synthesis in red blood cells, hence the prevalent opinion that it is a must-have prior to conception. The employment of red blood cells is important to the first half of pregnancy as this time covers the central nervous system including the brain and spinal cord in the fetal development, leading to a drop in folate levels before and during this stage.
If you are planning or currently pregnant, supplementing folic acid is a must, consider taking a prenatal multiple vitamin that has folic acid added!
EGCG in green tea
May 10, 2014 07:38 AM
Green tea benefits
Green tea is made from the leaves of Camellia Sinensis, which is recognized for its health benefits. The nonfermented product is obtained by leaf desiccation that contains potent, polyphenolic antioxidants, with a flavanolic structure referred to as green- tea catechins, including epigallocat-echin-gallate (EGCG). Studies have shown that drinking EGCG prevents carcinogenesis in rodent organs. Studies have shown it had a significant chemoprotective effect against DMBA-induced mammary tumorigenesis in rats. Human breast cancer cell proliferation inhibition by green tea appeared mediated in part by (CKI). Mutagenesis was inhibited at concentration levels equivalent to human daily consumption.
Using human umbilical vein endothelial cells, it was demonstrated that green tea extracts reduced expression of vascular endothelial growth factor (VEGF) receptors forms-like tyrosine kinase and fetal liver kinase. Kinase insert domain containing receptor. Because of the antiangiogenic property of its extracts, they have therapeutic potential in preventing the development of new microvascular networks (angiogenesis) needed for tumor growth. It was also found that green- tea polyphenols inhibited angiogenesis by reducing vascularization of chicken chorioallantoic membrane (CAM) by an angiogenin-like protein isolated from goat serum.
EGCG effectively inhibited bladder-tumor implantation growth in rats, pointing to its potential as an intravesical chemotherapeutic agent. Inhibition of platelet function is a factor in reducing the risk of coronary artery disease. EGCG was reported to inhibit platelet aggregation, by possibly involving inhibition of cytoplasmic calcium increase. EGCG was proven to be the most effective in reducing thrombin-induced aggregation of washed human platelets. The ability of green- tea catechins to inhibit adenovirus infection and adenain, the human adenovirus 2 endopeptidase, was reported. EGCG proved the most potent inhibitor of four green-tea catechins tested. The viral protease adenain appeared to be the target of EGCG, so it is possible that all adenoviruses are sensitive to its action.
The Chinese have known about medicinal qualities of green tea since ancient times, treating everything from headaches to depression.
The three "Es"
Provides support for a healthy weight loss program, gives the energy needed to maintain an active lifestyle, health, and longevity. The appetite suppressor, Vanadium, reduces calorie intake. Thermogenesis, or fat metabolism, is increased, because of the EGCG/caffeine combination, therefore burning fat.
EGCG fights free radicals. Fatty acids and lipids in the brain are susceptible to the effects of free radical perodixation. Much of the aging of the brain is attributed to perodixation. The EGCG helps to keep us young, alert, and able. Researchers have found that EGCG has inhibited tumor growth in both skin and gastrointestinal tracts. EGCG may fermented be able to obliterate cancer cells, without harming neighboring tissues.
Can Butcher's Broom Boost Cardiovascular Health?
October 30, 2013 09:48 PM
Where to find Butchers Broom
The butcher’s broom also known as ruscus aculeatus is an evergreen low shrub that grows in the Eurasian region. It is known to produce greenish flowers that are small sized and blooms during Spring. It has leaves that produce red berries after the falling off of its female flowers. It is reputed among native cultures as much as asparagus, with the roots been eaten in various preparations.
It is mainly recurrent in woodland as a result of bird-spread though is now grown as a garden plant in regions across the world. It has general names like the pettigree, Jews’myrtle, sweet broom, petit houx and knee holly. Its roots are deployed as medicines in different remedies.
It has been used as an effective tool to constrict capillaries and blood vessels by herbal and alternative medicine practitioners. Its efficiency in constricting blood vessels is considered to result from the constituent chemicals. This prevents the veins from pooling blood thereby improving the flow of blood in the hands, brain and legs.
It has been used to heal fractures and reduce swelling, as well as treatment for hemorrhoids and gallstones. It is reputed for constipation relief and ease of urine ejection.
As a result of its wide application and effectiveness, the German Health Commission listed it as a useful for the treatment of hemorrhoids. It is advised in medical circles that its use by pregnant women should be subject to consultation of a qualified medical practitioner to avoid possible contraindications and safeguard the fetal balance.
Clinical research is still open in several fronts to ascertain its virility and possible side effects as a result of the widespread usage across the globe by alternative medicine practitioners for a variety of medical conditions. This evidently will provide clues as to acceptable dosage and prescription in the years to come.
4. botanical.com: Broom, Butcher's
The Benefits of GLA to Women
June 15, 2011 11:10 AM
GLA, otherwise known as gamma linolenic acid or Omega-6 fatty acid, has been found to benefit women's health in a number of ways. For example, supplements of GLA have been found to reduce many symptoms of PMS, such as irritability, depression and breast pain. The reason for this may be due to the fact that at this time the metabolism of women is less able to convert dietary linoleic acid to GLA, the normal biochemical pathway for its production.
GLA is also of benefit to menopausal women, for whom it has been found to reduce the number of night flushes. GLA also helps to maintain fetal development in terms of new tissue grown and organ development, and in fact fetus development involves fairly high essential fatty acid consumption. Many women take one or two capsules of evening primrose oil intravaginally to soften the cervix in preparation for childbirth.
However, a small number of sources state that taking GLA in the latter stages of pregnancy should be avoided, so you should seek the advice of your doctor or physician on this question.
Essential fatty acids are essential for proper hormone production in women and men.
Make sure you are getting enough essential fatty acids daily!
Did You Know Lecithin is More than a Brain Food
February 15, 2011 04:16 PM
Lecithin, first discovered as the yellow substance in egg yolk, is now associated with a wide array of health benefits. It is in fact made up of a number of naturally occurring substances that all play an important role in promoting overall health at the right amounts. Today lecithin is made available as over-the-counter supplements and utilized for many different purposes in the food industry.
Lecithin has been proven to reduce cholesterol serum levels. For one, it has a direct effect on the digestion of triglycerides and cholesterol from the foods we eat, blocking the pathway that breaks down fats into smaller particles and their consequent absorption by intestinal walls. Also, lecithin has been observed to attract free fatty acids in the bloodstream and move them away from arterial walls. More importantly, it inhibits the release of bad cholesterol and instead raises good cholesterol levels.
Induces Weight Loss
There are dietary supplements that make use of lecithin to assist weight loss. Since the amount of lecithin present in our diet contributes to the ability of the intestinal walls to break down fats, notably cholesterol, it practically flushes away unwanted calories. Lecithin is a part of a class of compounds called lipids, and, as a lipid, it is readily utilized by the cells to burn fats and power cellular functions.
Phosphatidylcholine, a major constituent of lecithin, is in the employ of every cell in the body as a form of protection and in cellular communication. It is one of the compounds that make up the lipid bilayer of cell membranes. Unfortunately, our systems use up more lecithin as a dynamic source of energy than what we supply our body, and this explains why we become more susceptible to stress.
Protects the Liver
Lecithin has always shown to be one of the compounds that promote liver health, and has been in use against certain diseases of the liver such as cirrhosis. This compound is responsible for speeding up the metabolism of lipids in the liver, and produce them only when needed, thereby removing the hazards associated with the buildup of fatty tissues that interferes with the functions of the liver.
Helps during Pregnancy
Choline is one of the most important compounds during pregnancy. It is in itself an essential nutrient with established daily value, being required to support healthy body functions, and lecithin is its best known precursor. Intake of lecithin before getting pregnant is recommendable as choline must be produced at sufficient amounts prior to conception to ensure healthy fetal development.
Lecithin, being a precursor of choline, is involved in improving brain function. There are neuronal processes that rely entirely on choline, whose absence in the nervous system results in decreased activity of these processes. In addition, it has long been postulated that the functional decline tied to aging is due to the depleting levels of choline in the body. Hence, it is prudent to replenish our choline reserves by eating foods rich in lecithin.
B Vitamin Supplements
May 07, 2008 03:18 PM
The fact that B vitamins have had to be coenzymated before they can be used by your body has been known for some time, but it is only over the past few years that they have been made commercially available in that form. Before we discuss the B vitamins in their coenzyme form it might be appropriate to discuss what coenzymes are and how they differ from ordinary enzymes.
An enzyme is like an organic catalyst: it takes part in biochemical reactions by allowing such reactions to take place, but itself remaining unchanged. All enzymes are proteins formed in your body from amino acids and other protein material. A coenzyme, on the other hand, is somewhat like an enzyme for the enzymes, in that it is needed for the enzyme to do its job. Without a coenzyme, many enzymes could not promote the biochemical reaction it is responsible for.
The B vitamins are all water soluble, which means that they are readily excreted and it is not impossible that if you take a B vitamin supplement, the whole lot will be immediately excreted in your urine if not used by your body. Whether they are or not it is a fact that your body can quickly become depleted of the B vitamin group, especially if you drink a lot. Alcoholics in particular are frequently vitamin B deficient. Although the liver can store unused vitamin B, they are only very small quantities and insufficient to prevent a deficiency.
A deficiency in the B vitamins can cause a wide range of unpleasant conditions that are rapidly remedied with supplements. Pellagra is due largely to a deficiency in Vitamin B3, and causes hair loss, horrible skin lesions and many other side effects that you don’t want to know about. Vitamin B12 deficiency can cause loss of memory, and is common in alcoholics and some vegetarians (vitamin B12 is animal derived). Other symptoms of a general B vitamin deficiency include exhaustion, heart palpitations, fibrillation, anxiety, restlessness, attention deficit disorder and many, many more.
It is not pleasant so you make sure that take enough vitamin B in your diet: dietary sources are far superior to pills although supplements will help you get over the symptoms of the deficiency until your diet takes over. Supplementation is also a good way to maintain a regular supply of vitamin B complex irrespective of your diet. The effects of a deficiency are so bad that a regular supplement is well worth taking.
However, back to coenzymes and why they are needed for the metabolism of B vitamins in your body. Most B vitamins are, in fact, coenzymes themselves. Keep in mind that the definition of a vitamin is an organic substance that is essential for the normal health of your body. If you lack even one vitamin, your health with suffer and eventually you will be likely to die. That describes all of the B vitamins perfectly, and they also just happen to be coenzymes. This is not coincidence, of course, and their biochemistry must have been recognized before the concept of coenzymes was formulated.
The B vitamins proper consist of eight distinct proteins: B1 (thiamine), B2 (riboflavin), B3 (niacin), B6 (pyridoxine), B9 (folic acid), B12 (cyanocobalamin), and biotin and pantothenic acid. They are all essential components in human and animal metabolism, and most are also coenzymes.
Every cell in your body depends on B vitamins for its existence, which is why pregnant women should include a good supply of them in their diet, especially folic acid (B9). They are essential for the cellular development of the fetus. Folic acid is necessary for the synthesis of nucleic acids that allow cell growth and the production of red blood cells. However, not one can be placed in importance above any other since they are all essential.
With respect to the coenzyme factor, the vitamin B coenzymes are responsible for many of the biochemical reactions upon which life depends. Coenzyme B-12 for example is essential for two types of reaction that it catalyzes, one being a hydrogen atom exchange with alcohol and amine functional groups, the other being connected with methyl group transfer between molecules.
In humans, the first of these is responsible for an essential step that results in energy being metabolized from fats and proteins in the mitochondria and the second for DNA production in cells that is indirectly responsible for growth. Each of these is why a vitamin B-12 deficiency leads to excessive fatigue and also a lack of fetal growth (although folic acid can make up for the latter deficiency).
Thiamine (Vitamin B1) is a coenzyme for the metabolism of carbohydrates to energy. In the body it is present in the form of thiamine diphosphate, a coenzyme that assists in the decarboxylation of pyruvate as part of the citric acid cycle, otherwise known as the Krebs Cycle, that takes place in the mitochondria and is responsible for the generation of energy through aerobic respiration.
Another coenzyme that is involved in the Krebs Cycle is formed in the body from Vitamin B3, or niacin. This coenzyme, nicotinamine adenine dinucleotide, has a redox potential and can store energy for use later on. Vitamin B5 can be converted in the body to Coenzyme A that not only breaks proteins down into individual amino acids, but also takes part in the first part of the Krebs Cycle. There is a common pattern emerging here where the B vitamins have an important part to play in the generation of energy from fats and carbohydrates.
Similarly, Vitamin B6 is present in the body as the coenzyme Pyridoxal 5'-phosphate that helps to break down the body’s emergency energy store, glycogen, into energy when needed.
In these ways, and more, the coenzymes created in the body from the B vitamins help many of the reactions of life to take place, and without these coenzymes life could not exist. Hence the importance of the B vitamins themselves, and any deficiency could be disastrous to the metabolic processes that generate energy and keep you alive. It is not just the energy needed for exercise and normal human activity that will be compromised, but also that which keeps the heart beating and your diaphragm moving to allow you to breath.
Without a doubt, a Vitamin B supplement is one of the most valuable of all the vitamin supplements, and they are available in many forms. You might also find some of the B vitamins in their coenzyme form, though some of them may be unstable. However, whatever form they are taken in, Vitamin B complex should be one of the first on your vitamin supplement shopping list.
Are You At Risk And What Can You Do About It?
April 23, 2008 04:54 PM
Did you know there are Persistent Organic Pollutants (POPs) that can have an endocrine disrupting ability? Meaning, these chemicals can have an estrogen like and anti-androgen effect on the body, disrupting the normal function of our endocrine system which can cause all sorts of health issues.
Back in the industrial boom directly following world war II these chemicals were widely used in plastics, cosmetics, personal care products, cleaning agents, clothing, household furnishings, and decorations, food and water, fertilizers, and pesticides and fungicides. These chemicals are being banned by the government but are not gone all together yet.
Endocrine disruptor chemicals are fat soluble which means when consumed they are stored by the body in our fat stores. This makes these chemicals a persistent pain in the butt for a very long time since fat soluble substances tend to be stored and slowly released; some claim the release can be years and years down the road.
These types of toxins can easily leach into water including juices and can vaporize into the air that we breathe in to our lungs. Once ingested, these chemicals can lead to reproductive, developmental, behavioral, neurological, endocrine, and immunologic adverse health effects that can last a lifetime.
Those men and women who want to have children may discover that one of both at have reproductive impairments due to POPs. Symptoms of toxicity are male infertility, gynecological problems, and accelerated puberty, developmental abnormalities of the reproductive tract, premature delivery, behavioral problems, abnormal thyroid function, cancer and heart disease. In cases of children, signs of toxicity are leukemia when fetal exposure is experienced.
The wide spread use of phthalates in industrial and consumer products has raised a lot of concerns. Phthalates are what keep plastics flexible. Dibutyl phthalate is used in PVC piping (in new homes the piping that supply water to faucets), various varnishes and lacquers, safety glass, nail polishes, paper coatings, dental materials, pharmaceuticals, children’s toys, and plastic food wrap. The heating of plastic containers either by microwave or a hot cup of tea can easily leach these phthalate’s in to food or drink exposing humans to high amounts of this toxin.
Also, Parabens are high on the watch list for those health minded. Parabens are a group of synthetic chemicals used as a preservative in cosmetic and pharmaceutical products. The most common parabens are methylparaben, propylparaben, and butylparaben. These three are used as a bacteriocidal and fungicidal agent in many products we use every day. The FDA does not require approval of cosmetic ingredients before they reach the market place so cosmetic manufactures are free to use what ever they want in their products.
Parabens have been shown to have a mild estrogenic affect on the body, and are in practically all personal care products on the market today. If you are applying a name brand cosmetic onto your skin daily, take a look at the label to see if Parabens are used.
For those looking to stay away form all the above listed toxins look for products packaged in glass, PETE or HDPE bottles and containers. Look for packets lined with saran, and can linings made of polyolefins. Use biodegradable household cleaning agents and avoid sprays and insecticides. Cleaning supplies are not required to list ingredients so it is always buyer beware unless the label states it is free from PCBs, Parabens, and POPs.
Finally, when buying furniture avoid furniture that contains flame retardant PBDEs and limit children to the exposure of such furniture. Exposure to PBDEs can lead to some of the above listed symptoms and cause health problems. Staying healthy is a tough task with all the environmental toxins we face. By buying organic foods and avoid the above listed chemicals one can live longer and maintain better health over a lifetime.
Best Sugar Balance Svetol (green coffee extract)
May 05, 2006 06:30 PM
Best Sugar Balance featuring Svetol® Svetol® is an extract of green coffee obtained by the use of a traditional patented extraction process from the beans of the species Coffea canephora robusta Pierre. This species is particularly rich in the constituent known as chlorogenic acid. Svetol® green coffee extract contains less than 2% caffeine. The extract is standardized to contain between 45-50% chlorogenic acids.
In vitro (test tube) and in vivo research suggests that chlorogenic acids present in coffee may have the ability to regulate blood sugar concentrations after meals by acting on the intestinal absorption of glucose and improving the body's glucose tolerance. Clinical evidence also suggests that Svetol® green coffee extract may help to maintain a healthy blood sugar level when used as a part of the diet.*
Maintains healthy blood sugar levels when used as a part of the diet*
Chlorogenic acid is the major polyphenol compound found in Svetol® green coffee bean extract. In vitro and animal studies have been conducted to determine the potential actions of this polyphenol. Studies report that chlorogenic acid and related compounds have significant antioxidant potential and are responsible for the high reported antioxidant benefit of green coffee. Several studies suggest that consumption of coffee in the diet is one factor that is correlated to the maintenance of healthy neural function and healthy aging. Coffee has also been shown in vitro to suppress the production of various free radicals. The chlorogenic acid content of coffee has been determined to be a major factor in the free radical quenching properties of coffee. A study was conducted to assess the activity of coffee extracts against the production of hydroxyl radicals in an in vitro system. It was found that coffee extracts possessed significant suppressive activity against hydroxyl radicals. Of the compounds assumed to be responsible for this effect, the researchers concluded that the chlorogenic acids played a major role with some contributions from other compounds found in the extract. This compound may also strongly contribute to any potential neuroprotective effects seen with coffee consumption.1
Two further studies highlight a possible mechanism by which chlorogenic acid mediates its antioxidant activity. In one study, the FRAP (Ferric Reducing Antioxidant Power) assay was used to measure and compare the iron-reducing capacity of chlorogenic acid and caffeine. It was shown that the chlorogenic acid content of the samples tested was highly correlated with iron-reducing activity in this assay. Moreover, lighter roasted coffee samples (closer in nature to green coffee) had the highest iron-reducing activity. Caffeine did not influence the iron-reducing activity of the coffee samples.2 Iron compounds are known to mediate the production of radicals and often serve as catalysts for their production in the body. A second study shows that chlorogenic acid can bind to and Chelate certain iron compounds, preventing them from catalyzing radical-producing reactions. In this way, chlorogenic acid acts as a powerful antioxidant.3
Chlorogenic acid and related compounds have a dual effect on the production and suppression of free radicals. In the case of the hydroxyl radical, studies outlined previously suggest that chlorogenic acid suppresses the production of the radical due to its ability to chelate iron compounds, while other studies suggest that chlorogenic acid has direct scavenging effects on the hydroxyl radical.4 Dietary intake of this potent polyphenol may confer multiple benefits to human health.
Several studies further suggest that chlorogenic acid in coffee can have a beneficial effect on blood sugar levels when consumed as a part of the diet. A recent study assessed the effects of coffee and tea consumption on glucose tolerance in middle-aged Japanese men. In this study, the relationship between daily intakes of green tea or coffee and glucose tolerance status was measured by the oral glucose tolerance test (OGTT). More than 3,400 men participated in the study in which fasting glucose was measured before and 2 hours after administration of an oral glucose load. A self-administered questionnaire was used to establish daily levels of dietary coffee and green tea consumption over the past year. The results showed that those individuals who consumed the highest levels of coffee per day had lower fasting glucose levels (by 1.5%) and lower post-test glucose concentrations (4.3% lower) than those who did not consume coffee Chlorogenic acid and related compounds have a dual effect on the production and suppression of free radicals. In the case of the hydroxyl radical, studies outlined previously suggest that chlorogenic acid suppresses the production of the radical due to its ability to chelate iron compounds, while other studies suggest that chlorogenic acid has direct scavenging effects on the hydroxyl radical.4 Dietary intake of this potent polyphenol may confer multiple benefits to human health.
Several studies further suggest that chlorogenic acid in coffee can have a beneficial effect on blood sugar levels when consumed as a part of the diet. A recent study assessed the effects of coffee and tea consumption on glucose tolerance in middle-aged Japanese men. In this study, the relationship between daily intakes of green tea or coffee and glucose tolerance status was measured by the oral glucose tolerance test (OGTT).
More than 3,400 men participated in the study in which fasting glucose was measured before and 2 hours after administration of an oral glucose load. A self-administered questionnaire was used to establish daily levels of dietary coffee and green tea consumption over the past year.
The results showed that those individuals who consumed the highest levels of coffee per day had lower fasting glucose levels (by 1.5%) and lower post-test glucose concentrations (4.3% lower) than those who did not consume coffee on a daily basis. In this study, green tea consumption was not associated with any benefits on glucose concentrations.5
It is likely that the chlorogenic acid found in coffee plays a role in supporting healthy glucose metabolism, whereas the role of caffeine is not clear, with some reports suggesting an adverse effect on sugar metabolism.
A second study further confirms an effect of chlorogenic acid at inhibiting the absorption of glucose from the diet. This effect occurs in the small intestine. In this study, nine healthy fasted volunteers consumed 25 grams of glucose in 400 ml of water (the control group), caffeinated coffee, or decaffeinated coffee. Frequent blood samples were taken over the next 3 hours. It was found that glucose and insulin concentrations were higher 30 minutes after the consumption of caffeinated coffee than with either decaffeinated coffee or control (water).While caffeine has specific biological effects on raising glucose levels and impacting insulin profiles, chlorogenic acid was shown to have an antagonistic effect on glucose transport. Previous studies have also shown that chlorogenic acid significantly delays glucose uptake from the small intestine.6
RESEARCH ON SVETOL®
Svetol® is a unique extract of Coffea canephora robusta green coffee beans containing between 45 and 50% chlorogenic acids with less than 2% total caffeine concentration. As outlined above, many studies highlight the potential benefits of coffee compounds, including chlorogenic acid, for providing protection against free radicals and promoting healthy glucose metabolism. A number of other potential benefits have been discovered for these compounds. Svetol® has also been the subject of preliminary clinical studies that have shown exciting results.
In a pilot study, the effect of Svetol® on sugar concentrations after meals was evaluated in 15 individuals. In the same trial, the longer-term effects of Svetol® on weight management were also evaluated. Blood sugar concentrations were measured on two separate occasions. Patients were administered an oral glucose tolerance test (OGTT) in which they consumed a standard amount of sugar and had their blood sugar levels measured 1 hour after sugar intake. The first measurement was made on day 1 prior to taking Svetol® and the second OGTT was performed on day 2, after beginning the Svetol® regimen in which one tablet (200 mg per tablet) was administered 3 times during the day. Patients were fasted for at least 8 hours prior to the testing. The results showed that Svetol® was able to reduce blood sugar concentrations in 60% of the subjects. The mean reduction of blood sugar concentration in these individuals was 50%. The treatment was continued following the same regimen for 6 weeks to assess the impact of Svetol® on weight. The average weight loss of the participants was 1.5 kg (3.3 lbs) over the treatment period. 7
Based on the studies mentioned above and other related research on the ingredients in Svetol®, scientists have proposed two mechanisms of action whereby Svetol® may influence the metabolism and processing of glucose. The first mechanism seems to be an inhibitory action on glucose absorption from the diet. Svetol® may affect the uptake of glucose in the small intestine by modulating factors needed for sugar absorption.
The second mechanism relates to possible effects of Svetol® in the liver's ability to produce glucose. Chlorogenic acids have been shown in vitro and in animal studies to modulate the effects of certain enzymes in the liver that catalyze the production of glucose. By having this dual effect on sugar absorption and sugar production, Svetol® is an effective product for maintaining healthy blood sugar levels when used as a part of the diet.*
Svetol® is a natural food extract from green coffee beans containing a standardized amount of chlorogenic acid. Studies have shown that chlorogenic acid (up to 500 mg/kg/day) given to pregnant rats from the 5th through 12th day of gestation caused no maternal or fetal mortality and no adverse effects on the nervous system. Chlorogenic acids have also been shown to be non-mutagenic in tests on bacteria such as the Ames test. The LD50 of chlorogenic acids has been determined to be higher than 2500 mg/kg body weight. Svetol® is also extremely low in caffeine, with less than 2% caffeine contained in the extract, and is not expected to have any of caffeine's stimulant effects. Svetol® is extremely safe with no adverse effects having been reported while taking Svetol® at the recommended dosage.7
*This statement has not been evaluated by the Food and Drug Administration.This product is not intended to diagnose, treat, cure or prevent any disease.
1) Daglia M, Racchi M, Papetti A, Lanni C, Govoni S,Gazzani G. In vitro and ex vivo antihydroxyl radical activity of green and roasted coffee. J Agric Food Chem.2004 Mar 24;52(6):1700-4.
2) Moreira DP, Monteiro MC, Ribeiro-Alves M, Donangelo CM, Trugo LC. Contribution of chlorogenic acids to the iron-reducing activity of coffee beverages. J Agric Food Chem. 2005 Mar 9;53(5):1399-402.
3) Kono Y, Kashine S,Yoneyama T, Sakamoto Y, Matsui Y, Shibata H. Iron chelation by chlorogenic acid as a natural antioxidant. Biosci Biotechnol Biochem. 1998 Jan;62(1):22-7.
4) Zang LY, Cosma G, Gardner H, Castranova V, Vallyathan V. Effect of chlorogenic acid on hydroxyl radical. Mol Cell Biochem. 2003 May;247(1-2):205-10.
5) Yamaji T, Mizoue T, Tabata S, Ogawa S, Yamaguchi K, Shimizu E, Mineshita M, Kono S. Coffee consumption and glucose tolerance status in middle-aged Japanese men.Diabetologia. 2004 Dec;47(12):2145-51. Epub 2004 Dec 15.
6) Johnston KL, Clifford MN, Morgan LM. Coffee acutely modifies gastrointestinal hormone secretion and glucose tolerance in humans: glycemic effects of chlorogenic acid and caffeine. Am J Clin Nutr. 2003 Oct;78(4):728-33.
7) Berkem.Text on Svetol®.Gardonne, France: November 2005.
Mother's Choice with Iron - Scientific Prenatal Nutrition!
June 03, 2005 06:23 PM
You’re expecting a baby—and right now nothing could be more important than ensuring the health of your developing child. At this crucial time, what could be more basic than providing the nutrients that are the very substance of the new life you’re carrying? At every critical stage of pregnancy, your baby’s cells and tissues are literally formed from the nutrients you take in. Source Naturals is deeply committed to giving your newborn every chance for optimal health. That’s why we developed MOTHER’S CHOICE Prenatal Multiple. MOTHER’S CHOICE combines a comprehensive vitamin-mineral blend with advanced nutrients that reflect the latest scientific research. And each bottle comes with a separate package of Arctic Pure™ DHA softgels. DHA is a fatty acid that is crucial for baby’s brain development from the earliest stages of pregnancy through the breastfeeding years. MOTHER’S CHOICE also supports your health and vitality, with a blend of traditional herbs used for centuries to relieve morning sickness and leg edema. MOTHER’S CHOICE: because nothing is too good for you and your baby.
Go the Source for Scientifically Based Formulation
MOTHER’S CHOICE PRENATAL MULTIPLE was expertly formulated to supply a full range of essential vitamins and minerals, in potencies effective for maternal health and fetal development, while safe for the fetus.
Healthy Fetal Development
MOTHER’S CHOICE contains ingredients that reflect the latest findings in fetal nutrition.
Enjoy Your Special Time!
Pregnancy should be one of the high points of your life, but typical discomforts can get in the way. MOTHER’S CHOICE features herbs traditionally used during pregnancy. Morning Sickness: Ginger root and peppermint leaf are traditional remedies for the nausea associated with morning sickness, and chamomile has soothing properties. Leg Comfort: Vitamin E has been shown to relieve nocturnal leg cramps, while bilberry supports healthy capillaries and veins.
Take Charge of Your Pregnancy
Source Naturals understands your deep desire to safeguard your baby’s health and development. With MOTHER’S CHOICE you have the resources to act on that concern. MOTHER’S CHOICE: for a vibrant pregnancy and a good start on life for your newborn.
CAUTION: Pregnant or breastfeeding women should consult a health care professional before using this or any dietary supplement.
Mega Mind - re-align your body systems ...
June 03, 2005 05:24 PM
Aging and nutritional imbalances can disrupt the multiple body systems that affect healthy brain function. The result: cognitive symptoms* such as forgetfulness, inability to focus, and mental fatigue. MEGAMIND™ is a Bio-Aligned Formula™ that helps align multiple systems: neurotransmitter production, antioxidant defense, energy generation, circulation, and myelin sheath generation. Complementary Formulations Source Naturals can help keep your mind sharp and alert. Use MENTAL EDGE® Bio-Aligned Formula for foundational support, or MEGAMIND, when memory symptoms* are severe. HIGHER MINDTM is an additional Bio-Aligned choice. Take these formulas alone or as the core of a program that includes additional ingredients such as DHA (NEUROMINS®), GINKGO-24™, PHOSPHATIDYL SERINE, VINCAMINE, and VINPOCETINE.
In today’s complex world, we are bombarded with information. Our ability to process this massive input depends on how well we nourish the multiple body systems related to brain health. In addition, normal aging is associated with impairment of certain mental functions, according to the National Institute on Aging. The brain undergoes changes including functional decline in neurons important to learning, memory, planning, and other complex mental activities, as well as increased oxidative stress. In healthy people, these changes may result in varying degrees of age-related memory decline. Source Naturals can help, with a full line of cognitive support products.
Mental Edge®: Bio-Aligned Formula
MENTAL EDGE is a literal multivitamin for your brain. MENTAL EDGE supports production of neurotransmitters including acetylcholine, antioxidant defense, energy generation, stress response and myelin sheath generation. It features nutrients needed for production of neurotransmitters— chemical messengers in the brain’s communication system. One of the most important of these is acetylcholine, which is necessary for memory and muscle movement. MENTAL EDGE also contains antioxidants—vitamin C, ginkgo, DMAE, and zinc—to protect the neuron cell membranes where electrical signaling takes place. Adaptogenic herbs provide the brain with support and energy to deal with environmental stress. Energy-generating ingredients such as ginkgo and B-vitamins are vital to the high-powered functioning of your brain. Vitamins B-5 and B-12 are also important for formation of myelin, a substance that forms a protective insulating cover around certain nerve fibers and increases nerve impulse conduction.
MegaMind™: Bio-Aligned Formula When memory symptoms* are severe, you may need a formula with extraordinary cognitive support. MEGAMIND addresses many of the same body systems as MENTAL EDGE, but does so with megadoses of brain nutrients, such as L-pyroglutamic acid and vitamin B-1 for neurotransmitter production. It also adds bacopa and the inhibitory neurotransmitter GABA to support neurotransmitter production, and higher potency vitamin B-12 for myelin sheath generation. Like MENTAL EDGE, MEGAMIND supports energy generation and antioxidant defense. MEGAMIND augments basic support for the brain’s immense energy requirements with higher potency vitamin B-1, and with one of nutritional science’s most advanced, high-tech nutrients, alpha-lipoic acid. Lipoic acid is also an antioxidant, as are gotu kola and grape seed. MEGAMIND also supports circulation with ginkgo and gotu kola.
Mega Mind: Bio-Aligned Formula HIGHER MIND is another multi-system support formula, which features phosphatidyl serine, a structural component of nerve cell membranes, and the botanical vinpocetine. HIGHER MIND nourishes neurotransmitter production, cell membrane stability, energy generation, antioxidant defense and myelin sheath generation.
Neurotransmitter Production: Bacopa, GABA, L-Glutamine, L-Pyroglutamic Acid, Taurine, N-Acetyl L-Tyrosine, Manganese, Vitamins B-1 & B-6
Acetylcholine Production: Acetyl L-Carnitine, DMAE, Gotu Kola, L-Pyroglutamic Acid, Vitamin B-5
Myelin Sheath Generation: Vitamins B-5 & B-12
Energy Metabolism: Acetyl L-Carnitine, Ginkgo Biloba, L-Glutamine, alpha-Lipoic Acid, Calcium, Magnesium, Manganese, Potassium, Zinc, Vitamins B-1, B-2, B-3, B-5, B-6 & B-12, Biotin,Folic Acid
Circulation: Ginkgo Biloba, Gotu Kola
Antioxidant Defense: DMAE, Ginkgo Biloba, Gotu Kola, Grape Seed, alpha-Lipoic Acid, Zinc, Vitamin C
Complementary Cognitive Support Products
For additional support, you can supplement Source Naturals Bio-Aligned formulas with these single ingredient products: ACETYL L-CARNITINE and DMAE are both important to the synthesis of acetylcholine, a key neurotransmitter associated with higher cognitive functions, such as learning and memory. DHA (NEUROMINS®) is an omega-3 fatty acid that plays a significant role in cerebral development, especially during fetal development and infancy. GINKGO is renowned for promoting blood flow to the brain. Source Naturals GINKGO-24™ is a standardized concentration of Ginkgo biloba leaves, yielding 24% ginkgo flavone glycosides and 6% terpenes (the key constituents). PHOSPHATIDYL SERINE is necessary for the health of nerve cell membranes, where electrical signaling takes place. These membranes are critical to information processing. VINCAMINE, an alkaloid obtained from the periwinkle plant, supports cerebral metabolism by promoting blood flow and oxygen and glucose utilization. VINPOCETINE is a derivative of vincamine, shown in research studies to improve cognitive performance and alleviate the short-term memory loss that may accompany stress or aging.
Lifestyle Tips for Cognitive Health: A Strategy for Wellness SM
Eat Well: Recent research suggests that diets rich in beta-carotene and vitamins C and E help reduce memory problems, probably by lessening oxidative stress. And new animal research at the University of Toronto found that a high-fat diet slowed the ability of rats to learn new tasks. Use Your Brain: Learn a foreign language or new hobby, do crossword puzzles, read books, and cut back on TV. Scientists at Case Western found that people who were less mentally active in middle age were three times more likely to experience memory decline as they got older. Stay Active: Vigorous walking can improve mental processes in aging individuals, according to research. Aerobic exercise increases oxygenation and blood flow to the brain, resulting in improved memory, organization, and the ability to juggle intellectual tasks. Manage Stress: Longterm anxiety or depression can make a person more forgetful. Try to regulate stress, increase social contacts, and, if necessary, seek professional help. Get Organized: Make the most of your cognitive abilities, through the use of memory aids such as “to-do” lists, notes, or calendars.
KudZu, Treatment of alcohol dependence or alcohol abuse
May 19, 2005 09:29 AM
For millennia, folk medicines have been used to treat ‘‘alcohol addiction’’ in China. A thorough literature search of the ancient Chinese pharmacopoeias revealed a long list of traditional remedies, including the 16 ‘‘stop-drinking’’ formulae of Sun Simiao (ca. 600 AD) and the ‘‘anti-alcohol addiction’’ formula of Li Dongyuan (ca. 1200 AD), 2 of the most reputed ‘‘medical doctors’’ in the history of Traditional Chinese Medicine. However, like those discovered by the ancient Romans,11 most of the ancient Chinese remedies for ‘‘alcohol addiction’’ were based on psychological aversion: to deter patients from further drinking by associating alcohol drinking with an unpleasant experience. Interestingly, as time went by, treatments based solely on psychological aversion were gradually eliminated from the ancient Chinese pharmacopoeias, presumably because of their ineffectiveness and/or undesirable side effects. The only remedies that have survived this historical trial-anderror scrutiny are those consisting the root (Radix puerariae, RP) or flower (Flos puerariae, FP) of Pueraria lobata (a medicinal plant known to the West as kudzu). It was on the basis of this historical backdrop, we initiated the search of safe and efficacious anti-dipsotropic (alcohol intake suppressive) agents from RP. This approach has led to the discovery of daidzin,12 an isoflavone that has since been shown to reduce alcohol drinking in all alcohol preferring animal models tested to date.
Alcohol abuse and alcohol dependence (i.e., alcoholism) are serious public health problems of modern society. In the United States alone, an estimated 13 million adults exhibit symptoms of alcohol dependence due to excessive alcohol intake, and an additional 7 million abuse alcohol without showing symptoms of dependence according to U.S. Government projections from studies conducted in the mid-1980s. Alcohol dependence and abuse are very expensive: in economic and medical terms, it will cost the U.S. well over $200 billion in 1991 with no prospect of falling or leveling off. The social and psychological damages inflicted on individuals as a consequence of alcohol abuse, e.g., children born with fetal alcohol syndrome (FAS) and victims of alcohol-related accidental death, homicide, suicide, etc., are immense.
While it is generally accepted that alcoholism and alcohol abuse are afflictions with staggering international economic, social, medical, and psychological repercussions, success in preventing or otherwise ameliorating the consequences of these problems has been an elusive goal. Only very recently the public view that alcoholism and alcohol abuse are remediable solely by moral imperatives has been changed to include an awareness of alcoholism and alcohol abuse as physiological aberrations whose etiology may be understood and for which therapy may be found through scientific pursuits. Both alcohol abuse and dependence arise as a result of different, complex, and as yet incompletely understood processes. At present, alcohol research is in the mainstream of scientific efforts.
Our studies on alcohol (ethanol or ethyl alcohol) have been based on the hypothesis that its abuse can ultimately be understood and dealt with at the molecular level. Such a molecular understanding, if achieved, would provide a basis for the identification and development of appropriate therapeutic agents. Our view hypothesizes that the clinical manifestations of alcoholism and alcohol abuse are the consequence of aberrations or defects within one or more metabolic pathways, affected by the presence of ethyl alcohol. In order to test this hypothesis, our initial studies focused on physical, chemical, and enzymatic properties of human alcohol dehydrogenase (ADH), the enzyme that catalyzes alcohol oxidation according to the following reaction formula:
CH.sub.3 CH.sub.2 OH+NAD.sup.+ .fwdarw.CH.sub.3 CHO+NADH
In addition, our studies more recently have focused on the aldehyde dehydrogenases (ALDH) which catalyze the subsequent step in the major pathway of ethanol metabolism according to the following reaction formula:
CH.sub.3 CHO+NAD.sup.+ .fwdarw.CH.sub.3 COOH+NADH
Prior to our research (for example, see Blair and Vallee, 1966, Biochemistry 5:2026-2034), ADH in man was thought to exist in but one or two forms, primarily in the liver, where it was considered the exclusive enzyme for the metabolism of ethanol. Currently, four different classes of ADH encompassing over twenty ADH isozymes have been identified and isolated from human tissues. There is no reason to believe that all of these ADH isozymes are necessary to catalyze the metabolism of a single molecule, ethanol, even though all of them can interact with it. We have proposed that the normal function of these isozymes is to metabolize other types of alcohols that participate in critical, physiologically important processes, and that ethanol interferes with their function (Vallee, 1966, Therapeutic Notes 14:71-74). Further, we predicted that individual differences in alcohol tolerance might well be based on both qualitative and quantitative differences in isozyme endowment (Vallee, 1966, supra).
Our research has established the structures, properties, tissue distribution, and developmental changes for most of the ADH isozymes, which while structurally quite similar, and presumed to have evolved from a common precursor, are functionally remarkably varied. Of the more than 120 publications from our laboratory that relate to the above subjects, the following, arranged in six categories, are especially useful for instruction in the prior art.
Kudzu Recovery 60ct
Kudzu Recovery 120ct
Kudzu Root Extract 50caps
Kudzu Root Extract from Solaray 60ct