Elder Berries contain vitamins A, B and C plus various flavonoids including quercetin. However, these substances alone cannot account for its remarkable effect of disarming the symptoms of a cold or flu. An Israeli scientist, Dr. Madeleine Mumcuouglu, Ph.D., performed research that uncovered the mechanism of activity of Elder Berry's anti-cold and flu activity. The flu is triggered by a virus, which must invade living cells in order to reproduce and spread. The virus enters the cell by puncturing the cell's outer membrane with tiny spikes known as hemagglutinin. Dr. Mumcuoglu discovered that the active ingre- dients in Elder Berry bind onto the hemagglutin, deactivating it and ultimately preventing the piercing of the cellular membranes.

Scientific investigations collaborate the effectiveness of Elder berry. One scientific study tracked a reduction of flu symptoms during an outbreak of influenza. (Zakay-Rones Z, Varsano N, Zlotnik M, et al. Inhibition of several strains of influenza virus in vitro and reduction of symptoms by an elderberry extract (Sambucus nigra L.) during an outbreak of influenza B Panama. J Alt Compl Med 1995; 1:361-9.) An added advantage to the use of Elder Berry is its record of safety. There are no known adverse reactions to the use of Elder Berry, although the possibi-lity of an individual allergic reaction can never be discounted.

Nature's Answer® offers Elder Berry in an alcohol-free, tangy-tasting 4oz. liquid herbal extract form. This concentrated (1:1) maximum strength fluid extract contains 5,000mg of Elder Berry in each 1 teaspoonful dose. Nature’s Answer® also supplies Elderberry in two encapsulated products, Sambucus & Ester-C®, and Sambucus & Maitake Bio-Beta Glucan™.

A great companion product is Nature's Answer®'s Elder Flower (organic alcohol). Flowers from the Elder tree contain tannins that have been shown to help dry up excess mucous, and can act as an expectorant.

One final note...when deciding on an Elder berry liquid, remember to check the kind of sweetener it contains. Many brands add sugar or sorbitol, while Nature's Answer's® Elder berry contains only pure coconut glycerine.

Ester-C® is a licensed trademark of InterCal Corporation and manufactured under U.S. patent #4,822,816 and other patent applications.

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Date: June 30, 2005 09:27 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Echinacea - Choosing The Ideal Immune Support

Echinacea By Ellen J. Kamhi, Ph. D. with Dorie Greenblatt Echinacea, pronounced ek-i-NAY-see-a, is one herb that has become a “household” name in the 1990’s. Many refer to it as “Purple Cone Flower” because of its large purple daisy petals, which contain a hard and spiny center cone. These spines probably give the plant its name, since sea animals with spines are called “echinoderms”. Echinacea is indigenous to the U.S., and can be found both growing wild in many areas as well as in cultivated gardens. There are actually nine different species of the plant; two are most popular as remedies: Echinacea angustifolia and Echinacea purpurea. Echinacea has a long history of use by Native Americans, who have utilized the herb for a wide variety of treatments ranging from stings, poisoning, toothaches and swollen glands to colds and sore throats. It has also been touted as an ideal natural remedy for snake bites. In particular, the benefit of Echinacea as a treatment for snake bites brought national attention to the herb in the last half of the 1800’s. Dr. H.F.C. Meyer of Pawnee City, Nebraska first tried to interest Eclectic Physicians (doctors who used natural medicines) to use Echinacea as an herbal remedy for snake bites by volunteering to be bitten by a rattlesnake to prove its effectiveness. Although his dramatic offer was rejected, his enthusiasm and concerted efforts led to renewed interest and investigative studies on Echinacea, resulting in the herb’s emergence as one of the most popular natural plant therapies by the turn of the century.

Extensive studies on Echinacea’s medicinal properties continue to mirror the earlier usages of the herb as experienced by indigenous people. In fact, Echinacea is part of the official materia medica listed in the German Commission E. Monographs, a universally recognized publication reputed to be the official information authority on herbal medicines. The Commission lists a number of medicinal applications for Echinacea as an ideal treatment for such conditions as colds, chronic infections of the respiratory tract and lower urinary tract ailments, as well as topically for chronic ulcerations and slow healing wounds.

Echinacea has been shown to be a potent immune system stimulant. Nature’s Answer® offers an outstanding Echinacea fluid herbal extract formula in a unique blend that contains both Echinacea angustifolia root and Echinacea purpurea whole plant. Fluid extracts that feature both whole plant and root parts in the formula insure that the highest levels of the whole herb’s active constituents are maintained. A further advantage to this kind of supplement lies in its delivery system– liquids are faster to absorb and easier to assimilate by the body than tablets or capsules. Nature’s Answer®’s Echinacea formulas are available in either alcohol-free or organic alcohol forms. In addition, the alcohol-free supplements are also offered in a tasty grape or tangy orange flavor.

Two popular blends featuring Echinacea with other supportive herbs are Immune Boost™ and Re-Zist™. Immune Boost™ combines Echinacea with Wild Indigo and Maitake Mushroom. Re-Zist™ contains Echinacea, Goldenseal, Wild Indigo, Cayenne and Myrrh for potent support.

Echinacea is also recognized for its ability to enhance the resistance of cells to viruses, especially when used after cells have been exposed to colds and flus. As a preventative, formulas such as Nature’s Answer®’s Echinacea/Goldenseal (alcohol-free, organic alcohol) are ideal. This is an excellent supplement for soothing sore throats and helping to shrink swollen glands. An added benefit to the formula is the presence to berberine, the active ingredient in Goldenseal, which provides further wellness enhancement.

Many studies have focused on Echinacea’s possible use for ailments such as psoriasis and early rheumatoid arthritis. The herb also acts as an overall anti-inflammatory tonic. Nature’s Answer®’s Blood Support™ (alcohol-free) combines Echinacea with Dandelion, Licorice and other herbs for an anti-inflammatory effect. Allertone™ (alcohol-free) blends Echinacea with Mullein Leaf to help support the respiratory and sinus areas.

Most herbal practitioners suggest using Echinacea for short-term periods. There has been evidence to suggest that the herb loses its effectiveness when used over longer periods of time. Also, in the case of autoimmune illnesses, some people believe Echinacea may OVER-stimulate the immune system, although there is no solid research to back this contention. Echinacea is probably most effective if used in frequent doses for 5-7 days at the early onset of symptoms. It may also serve as a preventative during periods after known exposure or during extra stress, taking it two to three times a day every other or every third day. The German Commission E lists no known drug interactions or side effects with Echinacea. It is indeed one of the safest and most effective herbs for natural immune support today.

Echinacea seems well suited to life in the 90’s with all the stresses upon our immune systems. Its importance and effectiveness as an immune stimulant is as true today as it was in 1927 when Dr. Liebstein stated:

“Nature has probably destined Echinacea to be used for remedial purposes only, as a sustainer of vitality, an organizer of the defensive powers of the system, to such an extent as to be justly crowned the greatest immunizing agent in the entire vegetable kingdom....” written in 1927 by Dr. A. M. Liebstein (Foster, 1991)

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Date: June 18, 2005 09:11 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Mushroom Miracales

Mushroom Miracles by Bert Hoffman Energy Times, April 12, 2004

Mention mushrooms and few people immediately recognize these humble fungi as important tools that can be used to boost well-being. More often, folks identify mushrooms as food with a peculiar appeal. But mushrooms' potential impact on health far surpasses their culinary reputation.

You don't have to stretch your imagination too far to understand why mushrooms have been much neglected in the modern, Western medical search for plants that can boost health.

Unable to make chlorophyll, often dependent on the kindness of other nutrient-producing organisms for their survival, these humble fungal denizens of dark, damp spaces seem to prefer an anonymous existence that is out of sight and out of the consciousness of the scientific mind.

However, mushrooms have now assumed a spot in the center of the research spotlight. Because of their potent content of natural chemicals that appear to have a strong influence on human health and well-being, during the past decade mushrooms have been the subjects of intensive studies on how they can be used to reduce the risk of cancer and to treat these diseases.

Appropriately, this recent round of research began in a place that has long revered these diminutive organisms: Japan. Japan and other Oriental countries have traditionally recognized the immense value of mushrooms as both food and medicine.

Food and Medicine

As an ancient Chinese saying notes, "food and medicine share a common origin." And one of the very earliest Chinese medical books, Shen Noug's Herbal (Shen Noug Pen Ts'ao Jing), first noted the extraordinary beneficial effects of eating mushrooms 2,000 years ago, back in the first century.

More recently, but still well ahead of Western medical experts, in 1575, Pen Ts'ao Kang Mu (a Chinese compendium of medicinal therapies), written by Li Shi Zhen, outlined the medical benefits of about 20 mushrooms.

Nowadays, modern researchers believe mushrooms' usefulness stems from the fact they contain a wealth of antioxidants. But these aren't just any antioxidants. Scientists think that some of these chemicals can potentially drop your risk of cancer, significantly lower blood pressure, help the body fight diabetes, offer protection for the liver, alleviate some of the ill effects of inflammation, lessen the chance of blood clots and help the body's immune system fend off viruses and other microbes. Quite a collection of benefits for these lowly beings!

The 10,000-Year Mushroom

Through the ages, the reishi mushroom (also known variously as the Mannetake, or 10,000-year mushroom, and the Immortality Mushroom) has been the most popular mushroom in Chinese, Korean and Japanese cultures. The reishi mushroom is frequently depicted in a wide variety of traditional Oriental artwork and even puts in an appearance in Chinese royal tapestries.

To some, reishi's power goes beyond the natural and include the supernatural. Originally grown on aging plum trees, reishi is also sufficiently well regarded to be employed by the Japanese as a good luck charm. But you don't have to believe in the supernatural to be superbly impressed with reishi. The beneficial natural substances in reishi include steroids, lactones, alkaloids, triterpenes and polysaccharides.

Large Molecules

Of these chemicals, polysaccharides (complex chains of sugars) in particular have intrigued researchers looking into the way mushrooms help health. These polysaccharide macromolecules are very large (for molecules) and complex, a complexity that leads researchers to believe they are capable of conveying a huge amount of biological information that help the immune system stop cancer in its early stages. The differences in the benefits of various polysaccharides stems from their intriguing geometrical shapes.

Distinctive Differences

Even though two distinctive polysaccharides may contain the same number of carbon, hydrogen and oxygen atoms, their three-dimensional differences-the way they are structured and branch off in different directions-can endow them with very different health benefits.

Though they all share a basic structure (usually, these molecules consist of a main chain of atoms with various side chains), the slight variations of the side chains changes their effects.

By deciphering the microscopic structures of these molecules, scientists think they are beginning to uncover which ones are most effective against cancer. For instance, in isolating a particularly useful polysaccharide called beta-D-glucan from reishi, researchers have found that this substance fights tumors in lab experiments (Chem Pharm Bull 1981; 29: 3611).

Maitake Benefits

Meanwhile, beta-D-glucan and other extracts taken from the Maitake mushroom have also been shown to possess powerful anti-cancer effects in lab experiments (Immunopharm Immunotox; 19:175).

In one instance, researchers in the laboratory who were trying out various substances on prostate cancer cells found that applying extracts of Maitake results in a kind of programmed self-destruction (apoptosis) of these undesirable cancer cells (Molec Urol; 4:7). In addition, another substance known as Maitake d-fraction has been shown to strongly fight cancer in lab animals-in one study, their liver cancer growths were reduced by up to 90% (Ann NY Acad of Sci; 833:204).

At the same time, research in China on people has demonstrated that Maitake may help reduce tumors and alleviate the effects of leukemia (Alter Comp Ther 12/98; 420).

According to A.S. Daba and O.U. Ezeronye (Afr Jrnl Bio 12/03; 672), "Mushroom polysaccharides offer a lot of hope for cancer patients and sufferers of many devastating diseases.

" [These substances support]...a fundamental principle in Oriental medicine...[they help] regulate homeostasis of the whole body and... bring the diseased person [back] to his or her normal state."

The Activity of Active Hexose Correlated Compound Active Hexose Correlated Compound (AHCC), an extract taken from shiitake and other mushrooms, is a relatively new substance that is also being researched for its anti-cancer benefits.

Studies on AHCC began in Japan in the 1990s when scientists looked at how it could potentially help people recovering from liver cancer. In those tests, researchers found that giving people AHCC apparently helped them survive longer.

In the future, scientists feel certain that they will uncover even more anticancer uses for mushrooms and the chemicals they contain. A key advantage to these natural substances is their lack of side effects. For instance, in research on an anti-cancer chemical called lentinan, taken from shiitakes, investigators have found that less than one percent of people experience the kind of discomfort that make them discontinue treatment. (This chemical has been used to treat stomach cancer.)

But a long list of beneficial mushroom substances are probably still waiting to be discovered. More evidence of mushrooms' benefits: A study of mushroom workers in a part of Japan called the Nagano Prefecture found that these farmers enjoyed a significantly lower cancer rate than other inhabitants of that part of the country.

In the rest of Japan, about one in six hundred people dies of cancer. But that rate death rate drops to about one in a thousand for mushroom raisers who eat a diet heavy in mushrooms.

John Smith, PhD, from the University of Strath-Clyde, notes that "...increasing evidence [shows] mushrooms offer a remarkable array of medicinally important compounds that have yet to be evaluated by Western medical scientists." Mushrooms offer the best of both worlds: good health that tastes great.

--
Vitanet ®

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Date: June 13, 2005 10:31 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Botanical Arsenal - Plants can help our bodies fight off cancer's deadly ...

Botanical Arsenal by Fred Thomas Energy Times, May 3, 1999

The complexities surrounding the various types of cancer stem from the variety of ways in which these diseases can wreak their havoc. Luckily, the equally complex world of plants contains novel compounds that can help our bodies fight off cancer's deadly progress.

Research Expands

Research into these botanical compounds is mushrooming. An example: The mighty Maitake, a fungus with flair, alternately known as the king (it can grow as large as a basketball, worth its weight in silver to the ancient Japanese); the prince; the Hen of the Woods (it sticks out of from trees when it grows in the wild); and the dancing mushroom to those who leaped for joy when they found one growing in its native northeastern Japan.

Researchers today dub it with a new moniker: Herbal Heavyweight.

Mushroom with Potential

The Maitake, with such other medicinal mushrooms as shiitake and reishi, historically has been eaten to promote general well-being and vitality. In the modern lab, however, scientists focus on the potent immune enhancing powers of Maitake, which spotlight its cancer fighting potential.

Twenty years ago, Maitake, Grifola frondosa, was an obscure, largely unavailable mushroom. A series of significant Japanese studies then catapulted it into prominence-and popularity.

Maitake Magic

Hiroaki Nanba, PhD, of the department of immunology at Kobe Women's College of Pharmacy on Kobe, Japan, and a leading international researcher on Maitake, conducted the preliminary tests on the mushroom, demonstrating that it stimulates immune function and inhibits tumor growth.

In 1986, Dr. Nanba fed powdered Maitake to mice injected with tumor cells; 86.3% displayed inhibited tumor growth.

Dr. Nanba and his colleagues went on to run additional mouse tests, finally reporting that this potent mushroom "directly activates various effector cells (macrophages, natural killer cells, killer T-cells, etc.) to attack tumor cells."

From then, Maitake mushrooms were headed to fame as cancer ninjas.

Stoking The Immune Engine

Like other mushrooms, Maitake is rich in complex polysaccharides, immunomodulators that successive tests after Dr. Nanba's have shown to be effective in cancer and AIDS treatment.

The polysaccharides in Maitake have a unique structure, rendering them some of the most powerful to be studied (Chem Pharm Bull 1987:35:1162-8).

What makes Maitake a particularly hot property is beta-D-glucan, its primary polysaccharide. Studies show that the body absorbs it readily, at which point it effectively stimulates interleukin-1, natural killer cells and macrophages, anti-tumor warriors that battle solid cancers (Chemotherapy 1990;38:790-6; also International Conference on AIDS, Amsterdam, 1992).

Effective And Safe

In addition to lab tests, trials on people have shown that Maitake may offer powerful therapy against liver and stomach cancer (studies in China), breast and colon cancer (US research) and Kaposi's Sarcoma, the virulent cancer attacking AIDS sufferers.

Importantly, studies show that no side effects or interactions accompany Maitake's efficacy.

Maitake fortunately has won the interest and enthusiasm of the scientific community. Currently, researchers at the Cancer Treatment Centers of America, headed by Denis Miller, MD, are completing an exhaustive test of the anticancer and immunostimulatory actions of Maitake on folks with advanced colorectal cancer. These investigators hypothesize that the polysaccharide beta-glucans derived from the fruitbody of Maitake fight tumors and boost immune function. "Though it cannot be said that Maitake ...[is] the cancer cure," said Dr. Nanba in his closing remarks at the Adjuvant Nutrition in Cancer Treatment Symposium in Tampa, Florida, in October 1995, "one can safely say that they do maintain the quality of life of patients and improve the immune system, resulting in the possible remission of cancer cells with no side effects."

More Bodily Benefits

Maitake maven Dr. Nanba also has tested-with strongly positive results-the effect of Maitake on blood glucose, insulin and triglycerides in mice, whose levels of all three substances declined when they were fed the mushroom (H. Nanba working paper, Anti-Diabetic Activity by Maitake Mushroom, 1994).

With colleagues, Dr. Nanba showed that Maitake lowered blood pressure in hypertensive rats (Chem. Phann. Bu//36:1000-1006,1988). Other studies suggest it may accelerate weight loss.

This admirable adaptogen (meaning it helps the body adapt to stress and normalize its functions) is water soluble and may be eaten in food or taken as a supplement. Vitamin C is believed to intensify Maitake's beta-glucans and enhance their absorption.

Tea Time

It's not just what you eat that may help protect against cancer, but what you drink as well. Research from China and Japan, where tea is the everyday drink and rates of several cancers like breast and prostate are lower, may persuade you to turn over a new leaf in your own beverage choice. One of the first studies to spark interest in tea came from Shanghai (Journal of the National Cancer Institute, June 1, 1994), where people who drank two to three cups a day were found to have about a 60% reduction in the risk of cancer of the esophagus. The reason: tea leaves contain compounds called polyphenols, potent antioxidants.

In fact, in tests at the University of Kansas, three of these, known as catechins, far outshone the common antioxidant vitamins C and E. Clinical trials are just starting, but early results are encouraging. A team of Chinese scientists reported that in a third of people with precancerous mouth sores who drank three cups of a mixture of green and black tea the lesions shrank significantly.

Researchers at the Saitama Cancer Center in Japan found that green tea seems to improve the prognosis of breast cancer. They followed a group of women with early-stage tumors for seven years. Those who drank more than five cups of green tea a day were only half as likely to suffer a recurrence as patients who consumed fewer than four cups a day.

Lung Help

And at the University of Indiana, toxicologist James Klaunig found that the lungs of cigarette smokers who drank the equivalent of six cups of tea a day suffered 40 to 50 percent less damage from the toxins in smoke, potentially lowering their risk of lung cancer and other pulmonary problems. Simultaneously, research from Purdue University suggests tea's cancer-discouraging powers go beyond being an antioxidant. Scientists Dorothy and D. James Morre showed that a tea catechin dubbed EGCG inhibits a growth-promoting enzyme on the surface of many cancer cells-happily without affecting normal cells. And researchers at the Ohio State University College of Medicine found that EGCG counteracted another enzyme, urokinase, that helps cancer cells spread. To top it off, Mayo Clinic scientists recently showed that EGCG prompted prostate cancer cells to commit suicide (Cancer Letters, Aug. 14, 1998).

Tea Research

So far, most tea research has focused on green tea, and investigators agree it's more potent than the black tea most Americans favor. But because both kinds come from the same plant, Camellia sinensis (it's the processing that makes the difference as black tea is fermented, green tea isn't) both contain cancer-fighting polyphenols, just in different quantities. As long as the tea you drink (even decaffeinated) is fresh brewed, it's likely to provide some benefit; powdered and prepared teas probably don't. And adding milk may dilute the effect.

Astragalus Against Tumors

Astragalus, an herb commonly used in Asia to boost stamina, has impressed western doctors for its potential for helping people cope with chemotherapy. As John Diamon, MD, W. Lee Cowden, MD and Burton Goldberg point out in the Definitive Guide to Cancer (Future Medicine), "Astragalus appears to protect the liver against the harmful toxic effects of chemotherapy and may be effective in treating terminally ill liver cancer patients." (They cite a study in the Jrnl of Ethnopharmacology 1990, 30:145-149.) In addition, they point out, research in Japan supports using a ginseng-astragalus combination to improve the function of natural killer (NK) cells which can boost immunity (Japanese Jrnl of Allergy, 37:2, 1998, 107-114).

Other studies confirm astragalus' potential in fighting off cancer. Research at the General Hospital of PLA, Beijing, showed that flavonoids (pigments) in astragalus could help protect cell membranes from oxidative damage caused by ultraviolet exposure (Chung Kuo Chung Yao Tsa Chih, 21(12):746-8; 1996 Dec).

A study of laboratory animals at Cunma University in Maebashi, Japan, found that Astragalus could help preserve immune function against the harmful side effects of chemotherapy (Chung Kuo Chung Hsi I Chieh Ho Tsa Chih, 15(2):101-3, 1995 Feb).

Garlic Benefits

Like a flame attracting moths, garlic bulbs have irresistibly drawn the attention of medical researchers. A study at Aarhus University, Denmark, found that skin cells in laboratory dishes treated with garlic supplements lived longer, healthier lives than untreated cells (Jrnl Ethnopharm, 1994. 43:125-133).

Meanwhile, a long list of research demonstrates that garlic's phytochemicals may fight tumors and reduce the carcinogenicity of the pollutants and chemicals that assault us daily. A study in China reported in the American Journal of Chinese Medicine showed that garlic helped slow tumors in lab animals (1983, 11:69-73). Another study in the Journal of Nutrition found that compounds in garlic could "suppress the growth of human colon tumor cells" (126, 1355-1361).

Added to those benefits, Robert A. Nagourney, MD, reports in the Journal of Medicinal Food (1:1, 1998, 13-28), garlic may "modify the carcinogenicity of foodstuffs." In other words, studies show that garlic can make chemicals in foods like pork less likely to cause your cells to become cancerous. (Ind J Physiol Pharmacol, 39:347-353).

DNA Protection

DNA, the stuff that genes are made of, face constant threats from free radicals, caustic molecules that can alter cellular structure and possibly cause genetic mutations that lead to cancer. But research into what are called oligomeric proanthocyanidins (OPC), flavonoids (pigments) derived from fruits vegetables, grape seed extract and the bark of maritime pine trees shows that OPC may be able to shield DNA from injury.

In particular, studies of a grape seed extract called Activin have demonstrated this substance can help liver cell DNA escape a destructive process called peroxidation (FASEB, 11:3, 2/28/97).

In these experiments, Activin demonstrated the ability to inhibit the growth of tumor cells as well as slow the replication enzymes of HIV viruses. This protective ability proved to be more potent than that of vitamin C, beta carotene and vitamin E.

Future Promise

What does the future promise to reveal? Scientists believe that many unexamined plants probably contain undiscovered phytochemicals that hold great potential for helping us fight the cancer epidemic.

Certainly, if the next few years produce as many results as the past decade, the next millennium will witness a long line of cancer-prevention discoveries. Before long, you should be able to take advantage of these potent substances.

As you gulp your garlic, tip your tea cup, mull your Maitake, acquire Activin and await your astragalus, you may meditate on what may soon be added to our growing anti-cancer arsenal. Undoubtedly, scientists with a botanical bent will be uncovering more coveted anti-cancer secrets before too long.

--
Vitanet ®

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Date: June 13, 2005 10:06 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Recognizing the Signs: Roadmap to a Healthy Heart

Recognizing the Signs: Roadmap to a Healthy Heart by Louis McKinley Energy Times, January 2, 2004

From time immemorial, people have tuned into life's lessons that come from the heart. Sadly, times are changing: If you're like most inhabitants of today's harried world, you may be too distracted to detect important clues about your cardiovascular circumstances.

And while heart lessons may be more complicated than simply connecting the physiological dots, understanding those heart messages are imperative for improving and maintaining your heart health.

Every cell in your body relies on heart-powered blood flow to keep it supplied with nutrients, oxygen, hormones and other natural chemicals necessary for survival. Without that supply of life-giving substances, few cells in the body-including those within the heart itself-can survive very long.

And just as damage to a major roadway can cause mayhem with traffic patterns, damage to blood vessels and the heart can wreak a lumpy cardiovascular havoc that blocks the passage of blood and endangers your heart's well-being.

Your Heart Disease Chances

Within the last ten years, scientific research performed by investigators around the world has focused on the specific factors that most strongly influence your chances of developing heart disease and suffering either a heart attack or a stroke.

While much of your risk depends on your genetic inheritance and family history, several factors that determine your heart health are within your control.

The most important factors you can do something about include:

* Smoking: free radicals generated by burning tobacco causes significant damage to blood vessels and other cells

* Lack of exercise: the human body is designed for consistent, moderate physical activity; without exercise, the body slacks off in creating antioxidant protection for arteries

* Diabetes: when excess blood sugar persists, physiological processes begin that endanger the heart and arteries

* Cholesterol: when oxidized (a chemical process that has been compared to a kind of internal rusting), cholesterol can form artery-blocking plaque; antioxidant nutrients like vitamin C and natural vitamin E may help the body limit this process

* High blood pressure: excessive pressure within the blood vessels raises the risk of damage to the heart and arteries; a program of weight loss and exercise can help control blood pressure

* Being overweight: the extra body fat carried around your middle is linked to a greater risk of heart problems

Heart Attack Signs

Do you think you know what a heart attack feels like? Well, if you think it feels like a dramatic pain somewhere in your chest that knocks you to the floor, you're probably wrong. "Most heart attacks do not look at all like what one of my colleagues calls the 'Hollywood' attack-the heart attack you see on television or in the movies," warns Julie Zerwic, MD, professor of surgical nursing who has studied what happens when people develop heart disease and suffer damage to their hearts.

"The symptoms [of heart problems] are not necessarily dramatic. People don't fall down on the floor. They don't always experience a knife-like, very sharp pain. In fact, many people describe the sensation as heaviness and tightness in the chest rather than pain," she says. And, if you're a woman experiencing a heart attack, you may not even feel discomfort specifically in your chest. Instead you may experience a severe shortness of breath. The apparent ambiguity of the discomforts caused by a heart attack lead many people to either ignore them or take hours to realize they need to go to the emergency room at the hospital.

Consequently, much fewer than half of all individuals undergoing a heart attack actually go to a hospital within an hour of the start of the attack. That delay can be a fatal mistake.

"Timing is absolutely critical," laments Dr. Zerwic. "If treatment starts within a hour after the onset of symptoms, drugs that reestablish blood flow through the blocked coronary artery can reduce mortality by as much as 50%. That number drops to 23% if treatment begins three hours later. The goal is to introduce therapy within two hours."

However, in Dr. Zerwic's research, only 35% of non-Hispanic whites go to the hospital within an hour of the start of a heart attack. And among African-Americans, the number of people going to the hospital right away drops to a frighteningly low 13%.

Often, people will lie down or use a heating pad to relieve the tightness they feel in the chest," says Dr. Zerwic. "They may take some medicine and wait to see if that works. All these steps postpone needed treatment."

Signs of a possible heart attack include:

* Chest discomfort: Heart attacks most frequently cause discomfort in the center of the chest that can either go away after a couple of minutes (and come back) or persist. The discomfort may feel like strong pressure, fullness or pain.

* Upper body discomfort: An attack may set off pain or discomfort in either or both arms, and/or the back, neck, jaw or stomach.

* Shortness of breath: Chest discomfort is frequently accompanied by shortness of breath. But it's important to note that shortness of breath can take place even in the absence of chest discomfort.

* Other signs: You can also break out in a cold sweat, or feel nauseated or light-headed.

A Woman's Sleep Signs

If you are a woman who suddenly experiences a marked increase in insomnia and puzzling, intense fatigue, you may be in danger of an imminent heart attack.

In an attempt to understand how women's symptoms of heart problems differ from those of men, researchers talked to more than 500 women in Arkansas, North Carolina and Ohio who had suffered heart attacks. (Technically, what they had experienced is referred to as acute myocardial infarction.)

They found that chest pain prior to a heart attack was only reported by about 30% of the women surveyed.

More common were unusual fatigue, sleep disturbances and shortness of breath (Circulation Rapid Access, 11/3/01).

"Since women reported experiencing early warning signs more than a month prior to the heart attack, this [fatigue and sleep problems] could allow time to treat these symptoms and to possibly delay or prevent the heart attack," says researcher Jean C. McSweeney, PhD, RN, nursing professor at the University of Arkansas for Medical Sciences in Little Rock. In Dr. McSweeney's study, more than nine out of ten women who had heart attacks reported that they had had new, disturbing physical problems more than a month before they had infarctions.

Almost three in four suffered from unusual fatigue, about half had sleep disturbances, while two in five found themselves short of breath.

Other common signs included indigestion and anxiety.

"Women need to be educated that the appearance of new symptoms may be associated with heart disease and that they need to seek medical care to determine the cause of the symptoms, especially if they have known cardiovascular risks such as smoking, high blood pressure, high cholesterol, diabetes, overweight or a family history of heart diseases," says Dr. McSweeney.

Dr. McSweeney warns that, until now, little has been known about signs that women are having heart trouble or heart attacks. The fact that most of Western medicine's past attention has been on heart problems in men has obscured the warning signs in women. As part of Dr. McSweeney's studies, she and her fellow researchers have discovered that more than 40% of all women who suffer a heart attack never feel any chest discomfort before or during the attack.

"Lack of significant chest pain may be a major reason why women have more unrecognized heart attacks than men or are mistakenly diagnosed and discharged from emergency departments," she notes. "Many clinicians still consider chest pain as the primary symptom of a heart attack."

Vitamins for Diabetes and Heart Disease

Having diabetes significantly raises your chance of heart disease, which means that keeping your blood sugar levels under control can reduce your chances of suffering a heart attack.

Today, 17 million Americans have diabetes and, as the country's population in general gains weight and fails to exercise, the number of people suffering this problem continues to grow.

The first line of defense against diabetes consists of exercise and weight control. All you have to do is take a brisk walk for 30 minutes a day to drop your chances of diabetes (American Journal of Epidemiology 10/1/03).

"We have found that men and women who incorporate activity into their lifestyles are less likely to develop type 2 diabetes than those who are sedentary. This finding holds no matter what their initial weight," said Andrea Kriska, PhD, professor of epidemiology at University of Pittsburgh Graduate School of Public Health.

To help your body fight the development of diabetes, researchers also recommend vitamin C and natural vitamin E.

Researchers working with lab animals at the University of California at Irvine have found that these antioxidant vitamins can help insulin (the hormone-like substance secreted by the pancreas) reduce harmful blood sugar. In addition, these vitamins shrink the chances of organ damage that can be caused by diabetes (Kidney International 1/03).

In this investigation, these vitamins also helped reduce blood pressure, another risk factor that raises heart disease risk.

"Blood pressure was lowered to normal, and free radicals were not in sufficient numbers to degrade the sugars, proteins and nitric oxide," notes Nick Vaziri, MD, professor of medicine at the University of California. "We think this shows that a diet rich in antioxidants may help diabetics prevent the devastating cardiovascular, kidney, neurological and other damage that are common complications of diabetes."

Free Radical Blues

Dr. Vaziri and his group of researchers found that untreated diabetes raised blood pressure and increased the production of free radicals, caustic molecules that can damage arteries and the heart. Free radicals can change blood sugar and other proteins into harmful substances, boosting tissue and heart destruction.

In Dr. Vaziri's work with lab animals, he found that treating diabetes with insulin lowered blood pressure and helped keep sugar and protein from changing into dangerous chemicals, but allowed the free radicals to subvert nitric oxide, a chemical the body uses to protect itself from free radicals.

In this investigation, adding vitamins C and E to insulin insulated the body's sugars, proteins and nitric oxide from oxidative assault. This produces a double advantage: Lowering the risk of heart disease and other damage to the body from diabetes.

Maitake, an Oriental mushroom that has been shown to have many health benefits, can also be useful for people with diabetes who are trying to avoid cardiovascular complications. Laboratory studies in Japan demonstrate that Maitake may help lower blood pressure while reducing cholesterol (Biological & Pharmaceutical Bulletin 1997; 20(7):781-5). In producing these effects, the mushroom may also help the body reduce blood sugar levels and decrease the risk of tissue damage.

No Smoking!

Tobacco smoke is one of the most notorious causes of heart problems. In the same way a hard frost exerts a death grip on a highway, the smoke from cigarettes can freeze up arteries and hamper their proper function. A healthy artery must stay flexible to comfortably allow adequate circulation.

But "...when blood vessels are exposed to cigarette smoke it causes the vessels to behave like a rigid pipe rather than a flexible tube, thus the vessels can't dilate in response to increased blood flow," says David J. Bouchier-Hayes, MD, professor of surgery at the Royal College of Surgeons in Ireland, who has studied the deleterious effects of tobacco.

This rigidity is called endothelial dysfunction. When arteries are rigid, blockages gum up vessels, clots and other impediments to blood flow appear, and your risk of heart attack and stroke increases (Circulation 2001 Nov 27; 104(22):2673).

This condition can also cause chest pain (angina) similar to that caused by a heart attack, and should be evaluated by a knowledgeable health practitioner.

Although all experts recommend you stop smoking to lower your heart disease risk, some studies have found that Pycnogenol(r), a pine bark extract that helps the body fight inflammation, may ease some of smoking's ill effects.

In a study of platelets, special cells in the blood that can form dangerous blood clots, researchers found that Pycnogenol(r) discouraged platelets from sticking together (American Society for Biochemical and Molecular Biology 5/19/98). By keeping platelets flowing freely, this supplement may alleviate some of the heart-threatening clots that tobacco smoke can cause.

In Ayurvedic medicine, a traditional therapy from India, an herb called guggul has also been used to lower the risk of blockages in arteries. This herb, derived from the resin of the mukul tree, has been shown to reduce cholesterol by about 25%. People taking this herb have also reduced their triglycerides (harmful blood fats) by the same amount (Journal Postgraduate Medicine 1991 37(3):132).

The Female Version of Heart Disease

Cholesterol and Heart Health
Controlling cholesterol (as mentioned before), the fat-like material running around your blood that can block arteries, is considered crucial for protecting your cardiovascular system. A new tool in the cholesterol battle is a natural substance known as potassium hydrogen d-glucarate, a chemical which your body makes and is found in fruits and vegetables. Studies on research animals have shown that potassium hydrogen d-glucarate can lower blood cholesterol, even lowering LDL ("bad" cholesterol) by more than a third. Noni, made from a tropical fruit, is another natural substance attracting attention as a possible helper for heart health and other chronic conditions. Traditionally, noni has been used to treat a wide variety of problems, including intestinal difficulties and arthritis. While some researchers are looking into its anticancer properties, it is reputed to help lower blood pressure and function as an adaptogen, boosting the body's ability to resist infection and deal with stress.

Nuts and Heart Health
Back in the early days of nutritional advice for heart health, some experts recommended against eating nuts: After all, they are high in fat and it was thought that high fat diets could compromise the function of your cardiovascular system. However, studies of people who go nuts for nuts and who eat walnuts, cashews, pecans, macadamias, pistachios, almonds and more found these nut lovers suffer less heart disease than non-nut consumers. Part of the good news about nuts, researcher believe, derives from the mineral magnesium found in nuts (and also contained in leafy green vegetables, legumes and whole grains). A magnesium deficiency may contribute to heart problems. In addition, the fats in nuts are monounsaturated, the same kind of heart-healthy fats found in canola and olive oils. Within nuts are also found a good deal of fiber, flavonoids and other natural substances that seem to protect the heart and arteries. Consequently, research indicates that if you eat nuts every weekday you may reduce your risk of heart problems by about two-thirds (Nut Rev, 2001;59:103-111). Of course nuts aren't the only vegetarian way to stay heart healthy. Foods such as oatmeal which are rich in soluble fiber, fiber that can be dissolved in water, also may lower your cholesterol. In addition, plant compounds known as sterols can improve your cardiovascular well-being. Researchers have been looking at these natural chemicals for the last 50 years and have found that they can significantly drop cholesterol (Am J CLin Nut 1995;61:392-396).

Vegetarianism vs Heart Disease
A vegetarian diet, in general, conveys more health benefits than eating meat. (Though fish, which contain heart-healthy omega-3 fatty acids, also lowers the risk of circulatory disorders.) In addition, mushrooms are attracting more attention from researchers as possible sources of heart-helping compounds. In Japan, for instance, health practitioners use the Maitake mushroom for treating high blood pressure and lowering cholesterol. (If you suffer from cardiovascular abnormalities, consult your health practitioner.) Maitake has already established a growing reputation for possibly fighting cancer (Cancer Prev 9/30/95;768:243-245). Adjusting to the latest advice on protecting your heart doesn't require radical changes in lifestyle. A touch of exercise, a spattering of heart-healthy nutrients: Before you know it, you can be headed down cardio road and heir to a cardiovascular system that systematically functions better than ever.

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Date: June 04, 2005 10:08 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Mushroom Immune Defense - Scientific Immunity Formula

Mushroom

The immune system is a fascinating and complex group of cells and biochemical processes. Its many components work to protect you from environmental threats—but your immune system requires nutritional support to function optimally. Scientific research is proving that some of the most powerful immune-supportive nutrients are found in mushrooms. People who realize the critical importance of optimizing immune function should seriously consider adding an advanced mushroom complex to their daily regimen. No other mushroom formula offers the high-potency, broad-spectrum benefits of Source Naturals MUSHROOM IMMUNE DEFENSE. MUSHROOM IMMUNE DEFENSE features 16 of the best-studied species of health-supportive mushrooms, including shiitake, reishi, and Maitake. These mushrooms contain compounds, including beta-glucans, glycoproteins and polysaccharides, that support a wide range of immune defenses: natural killer cell, T-cell and macrophage activity, and cytokine production. By combining a wide variety of mushrooms and fortifying them with extracts to ensure high potency, MUSHROOM IMMUNE DEFENSE offers a biochemically diverse formula that provides optimum immune assistance.

How Do Mushrooms Work?

Mushrooms are a treasure trove of bioactive compounds, but most of their immunomodulating activities have been attributed to polysaccharides (long-chain, simple sugars) and glycoproteins (polysaccharides naturally associated with proteins). These compounds activate a variety of immune responses.

Broad-Range Protection

MUSHROOM IMMUNE DEFENSE contains mycelia (networks of fibrous filaments) and extracts from the widest variety of mushroom species available. Included are the following mushrooms, which have demonstrated the most evidence for immune defense. Shiitake (Lentinula edodes): Lentinan, the beta glucan from shiitake, has been studied more extensively than similar substances and may be one of the most effective immunomodulators. Numerous studies have shown its ability to stimulate natural killer cell, T-cell, and macrophage-dependent responses.

Reishi (Ganoderma lucidum): Reishi’s polysaccharides may stimulate macrophages and enhance T-cell proliferation, according to in vitro studies.

Maitake (Grifola frondosa): Maitake enhances the activities of natural killer cells, T-cells and macrophages, according to animal studies. MUSHROOM IMMUNE DEFENSE contains MaitakeGold 404™, a highly specialized Maitake product, rich in beta-glucans, which is the only Maitake betaglucan fraction endorsed by the world’s premier Maitake researcher, Dr. Hiroaki Nanba, Ph.D. Turkey Tails (Trametes versicolor): These mushrooms have a long history of traditional use in Asia. One in vitro study suggests that its polysaccharides stimulate macrophages.

Almond portabella (Agaricus blazei): This mushroom may stimulate the immune system by increasing T-cell activity, according to animal studies.

Cordyceps (Cordyceps sinensis): Cordyceps came to international attention during National Games in China when, in one week, three women’s track and field world records were broken. The coach partially credited a cordyceps elixir. Cordyceps was found to augment antibody and other immune responses in one animal study, and a cordyceps polysaccharide was found to elevate cytokines in vitro.

MUSHROOM IMMUNE DEFENSE contains 10 additional mushrooms, including enoke, oyster, Polyporus umbellatus, and Poria cocos. Vitamin C is added to enhance absorption and activity.

Unparalleled Immune Support

A focus on immune support can pay tremendous dividends for your entire life. If you are dedicated to good health, you want a powerful formula on your side. Source Naturals is proud to join forces with your natural foods retailer to bring you an unparalleled immune formula: MUSHROOM IMMUNE DEFENSE.

References
Kurashige S, et al. 1997. Immunopharmacol Immunotoxicol 1997 19(2):175-83. Wang S. Y. et al. 1994. Program and Abstracts of the ’94 International Symposium on Ganoderma Research. Beijing: Beijing Medical University. Wasser S. P. and Weis A. L. 1999a. Crit Rev Immunol, 19, 65-96.

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Date: June 02, 2005 10:51 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Gluco Sciense - Take Control of your Blood Sugar ...

Gluco Sciense for Blood sugar

Sedentary lifestyles, obesity, and sugar-rich diets are prevalent in our society. The result: challenges to your multiple, interdependent body systems involved with blood sugar levels and insulin activity. Now is the time to learn how a healthy diet and lifestyle can help you maintain healthy blood sugar levels. For further support, Source Naturals offers you GLUCO-SCIENCE™, a breakthrough formula. GLUCO-SCIENCE is uniquely effective because it is a Bio-Aligned Formula™. Source Naturals evaluates the underlying causes of system imbalances. Then we design formulas that provide targeted nutrition to bring your interrelated body systems back into balance. GLUCO-SCIENCE can help bring your body’s systems for carbohydrate metabolism back into alignment.

A Bio-Aligned Formula™

GLUCO-SCIENCE is a comprehensive herbal-nutrient formula, based on the newest clinical research into key herbs and special ingredients. Source Naturals studied the scientific research, and then designed GLUCO-SCIENCE. This Bio- Aligned Formula provides targeted nutrition to five different body systems involved with healthy blood sugar levels and insulin activity.

Glucose/Carbohydrate Metabolism

GLUCO-SCIENCE supports glucose/carbohydrate metabolism with a range of nutrients. B-vitamins are required for glycolysis and the Krebs cycle, the metabolic pathways by which the body converts glucose into cellular energy. Chromium is believed to work closely with insulin to facilitate the uptake of glucose into cells. Manganese is also involved in glucose uptake. The formula also features herbs from several traditions, such as Gymnema sylvestre.

Insulin/Pancreatic Activity

Insulin is secreted by the pancreas in response to high blood glucose levels after meals. Without insulin, glucose cannot enter cells to provide fuel for cellular energy. Certain nutrients (see chart) support these vital metabolic processes, including mediation of insulin release and activity, and enhancing insulin sensitivity. N-acetyl cysteine protects pancreatic beta cells from oxidative damage in animal studies. In addition, vanadium, zinc, and selenium are notable for their insulin-like actions.

Heart and Circulatory System

Vitamin E supports a healthy lipid status, while myricetin has been shown in animal studies to influence triglyceride levels. Gymnema sylvestre and vitamin C are involved with lipid metabolism. Additional heart-healthy ingredients include CoQ10, garlic, fenugreek, and hawthorn.

Nervous System

Antioxidants are important for a healthy nervous system. Lipoic acid helps prevent lipid peroxidation, which can impact nerve function. Many B-vitamins are vital to the metabolic processes of the nerves or are present in the phospholipids of cell membranes. Methylcobalamin, an active form of vitamin B-12, supports the central nervous system. Other supportive ingredients are included (see chart).

Vision

GLUCO-SCIENCE provides antioxidants, nutrients and herbs with an affinity for eyes and the physiological processes involved in sight. Alpha-lipoic acid, quercetin, and vitamin C support healthy lens function. Bilberry, shown to support microcirculation in animal studies, is widely recognized for supporting vision.

Lifestyle Tips for Healthy Blood Sugar Levels: A Strategy for WellnessSM

Help Maintain Healthy Blood Sugar levels with Gluco-sciense.

Glucose/Carbohydrate Metabolism American Ginseng, Bitter Melon, Blueberry, Fenugreek, Gymnema sylvestre, Maitake, Myricetin, Pterocarpus marsupium, Chromium, Magnesium, Manganese, Vitamins B-1, B-2, B-5, B-6 & B-12, Biotin, Inositol, Niacinamide Insulin/Pancreatic Activity alpha-Lipoic Acid, Bitter Melon, Gymnema sylvestre, Maitake Fruit Body, Myricetin, N-acetyl-L-Cysteine, Pterocarpus marsupium, Taurine, Chromium, Manganese, Selenium, Vanadium, Zinc Heart and Circulatory System Bilberry, Blueberry, CoQ10, Fenugreek, Garlic, Grape Seed, Gymnema sylvestre, Hawthorn, Myricetin, Taurine, Siberian Ginseng, Magnesium, Selenium, Vitamins B-6, C & E, Folic Acid, Niacinamide Nervous System alpha-Lipoic acid, Glutamine, Magnesium, Taurine, Vitamins B-1 & B-6, Biotin, Choline, Inositol, Methylcobalamin Vision alpha-Lipoic Acid, Bilberry, Quercetin, Taurine, Zinc, Vitamins B-6, C & E

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Date: June 01, 2005 09:59 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: CAT’S CLAW DEFENSE COMPLEX - Health Secrets from the Rainforest

CAT’S CLAW DEFENSE COMPLEX

Standard pharmaceutical drugs came into common use only around the turn of the century. Before that, herbal preparations were administered for health concerns. Today, in nearly every country in the world, herbs are used by health care practitioners as the focal point of health care. Only in the United States is the otherwise widespread use of herbs missing in mainstream culture. But now modern scientific investigation is confirming the benefits of herbal supplementation, which is paving the way for us to reclaim and implement herbs into our everyday lives.

The primary need for preserving the rainforests

Rain Forest Herbs

Scientists’ knowledge of the varied rain forest flora is far from complete. The plants which have been thus far identified are so elaborate in molecular structure that it’s difficult to understand how these molecules function, let alone how to reproduce them. What is known is that the biodiversity of the rain forest yields numerous biologically active plant constituents which can have a profound influence on supporting the body through times of imbalance. Preserving the rain forest means preserving these precious herbs and the unique constituents contained within them.

Cat’s Claw Defense Complex contains powerful rainforest herbs

A Synergistic Blend

Source Naturals CAT’S CLAW DEFENSE COMPLEX harnesses the power of some of the most complex botanicals on earth into a synergistic blend of defense-enhancing herbs, each with a unique set of compounds which complement the body’s natural physiology. Source Naturals CAT’S CLAW DEFENSE COMPLEX is the first step in the rediscovery of a long-standing herbal tradition. Source Naturals was the first full-line supplement company to introduce the herbal superstar, Cat’s Claw, and the first to offer it in a combination formula. CAT’S CLAW DEFENSE COMPLEX provides 2000 mg of Cat’s Claw per four tablets – more than many companies’ single ingredient Cat’s Claw products! It combines powerful rain forest herbs like Pau D’Arco and Western herbs such as Aloe Vera and St. John’s Wort with legendary Chinese herbs (Reishi Mushroom and Astragalus). Source Naturals Cat’s Claw Defense Complex also includes two categories of antioxidants for broad spectrum support.

How we ensure quality and potency

Cat’s Claw & Pau D’Arco – Peruvian Jungle Discoveries

Cat’s Claw was discovered in the depths of the Peruvian Amazon jungle. Researchers have discovered that components extracted from the herb can bolster the body’s innate defenses, address discomforts associated with stress, and support intestinal health. Source Naturals uses only the highest quality Cat’s Claw inner bark – which is at least twenty years old, the amount of time it takes the bark to reach its peak biological activity– and uses a careful process to insure that harvesting the bark doesn’t weaken or destroy the plant. Like all of our herbs, each shipment of Cat’s Claw is also routinely inspected and tested by a trained herbalist to ensure maximum quality and potency. Pau D’Arco is also native to the South American rain forest and, like Cat’s Claw, has a high concentration of active constituents – a combination of anthraquinones and naphthoquinones, primarily lapachol – in the bark of the plant. Each daily dosage of CAT’S CLAW DEFENSE COMPLEX contains 100 mg of Pau D’Arco bark and 100 mg of concentrated Pau D’Arco bark extract for broad spectrum support.

Herbs — Adaptogens for Balance

Of the Chinese herbs, Siberian Ginseng is one of the best known adaptogens. Adaptogens have a balancing effect, helping us adapt to increased stress levels and other changes, like different altitudes or time zones. Thus, supplementation with Siberian Ginseng can help prevent stress-related health concerns. Schizandra, a small creeping vine with red berries, is a Chinese adaptogen which helps regulate the body’s functions and cleanse it of toxins.

Herbs that energize the body and build resistance to impaired bodily function

The trio of Chinese mushrooms – Reishi, Shiitake, and Maitake – has been used by Chinese herbalists for centuries, and provides the highest quality natural support for the body’s defenses. Modern science has revealed the true power behind Reishi, Shiitake, and Maitake: high levels of polysaccharides – long chain sugar macromolecules which are known for their protective and cleansing abilities. CAT’S CLAW DEFENSE COMPLEX utilizes only the mycelia biomass of Reishi (200 mg), Shiitake (200 mg), and Maitake (150 mg) to ensure the highest level of activity. Astragalus is the premier tonic – or internal strengthener – of Chinese herbalism. In addition to helping energize the body, Astragalus also builds resistance to weakness and to impaired bodily function. Isatis is a cooling herb which has been shown to have a broad spectrum inhibitory action in in-vitro studies, and helps support normal liver function. Used for thousands of years, the aloe plant has been treasured for its varied uses both externally and internally. Aloe Vera juice is high in mucopolysaccharides, which have been found to have powerful protective capabilities. CAT’S CLAW DEFENSE COMPLEX provides 200 mg of aloe (200:1 concentration) extracted from the whole leaf of the plant.

Why St. John’s Wort is powerful and useful

It is generally agreed that hypericin and pseudohypericin, two bioflavonoids which are the active constituents in St. John’s Wort, probably act as monoamine oxidase (MAO) inhibitors, which current research has shown are powerful as internal cleansing agents. St. John’s Wort is particularly useful because of its ability to cross the Blood-Brain Barrier, through which many elements are unable to pass.

The liver’s health is essential because of its responsibility for over 500 different functions

Antioxidants and Plantioxidants – Supporting Complete Health

Source Naturals CAT’S CLAW DEFENSE COMPLEX includes key liver-supporting antioxidants like Zinc, Beta Carotene, and Vitamin C – nutrients that help protect the liver from stress and pollution induced free radical damage. These three nutrients are also wellknown for their ability to help strengthen the body’s resistance and move through imbalances quickly. The liver is responsible for over 500 functions, including converting vitamins to their active forms, and processing and eliminating waste products from the body; therefore its health is vital. Plantioxidants™ is Source Naturals’ term for Plant-Derived Antioxidant Bioflavonoids. Though most people are only aware of the vitamin and mineral antioxidants, the latest scientific research has indicated that the plant kingdom may provide the most potent antioxidants in the world. Plants, trees, and citrus fruits all contain bioflavonoids (also called polyphenols) – a large group of restorative compounds with similar chemical structures which help protect the body from the ravages of oxidative damage due to free radicals. Some of the Plantioxidants included in CAT’S CLAW DEFENSE COMPLEX are: Quercetin, which helps inhibit the body’s sensitivity to dangerous particles in the air; Proanthodyn, which promotes tissue repair by helping to strengthen collagen and elastin, the two primary structural components in cartilage; Silymarin, which promotes liver-tissue regeneration and optimizes liver-cell function; Green Tea, a remarkably potent antioxidant; and Ginkgo, which is renowned for helping transport oxygen to the brain.

The way to naturally bolster the body’s defenses

A Holistic Natural Answer

The natural world provides us with a seemingly endless supply of complex herbal compounds with unreplicable and unique constituents so varied and numerous that most doctors aren’t even aware of their existence. Source Naturals would like to change that with CAT’S CLAW DEFENSE COMPLEX – the natural way to bolster the body’s innate defenses. All the ingredients included are at optimal potencies, and in the forms best absorbed by the body. The result? The most powerful, holistic product available to help maintain the structure and function of the natural defenses – Source Naturals CAT’S CLAW DEFENSE COMPLEX.

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Date: May 26, 2005 10:49 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: MaitakeGold 404® and Certified immune-stimulative activity ...

Dr. Nanba's Maitake Beta Factor & Dr. Nanba's Maitake-Pro Certified Immune-Stimulative Activity

By now, many people are aware of the numerous benefits of mushrooms, especially for immune health. But not all mushroom products are created equal. Planetary formulas offers Dr. Nanba's Maitake Beta Factor and Dr. Nanba's Maitake Pro. These products feature MaitakeGold 404®, a specialized beta glucan fraction with important health promoting properties. And every lot comes with certified proof of immune bioactivity -- so customers can be assured they are getting the benefits they look for in a mushroom product.

Immune Active Certification program

Phagocytosis is the process by which cells (White blood cells, for example) engulf and digest foreign organisms. As the body's first line of immune defense, phagocytosis is understoood to be one of the most important activities in immunology. For an immune support prodcut to be of benefit, it must be able to stimulate phagocytosis, thereby protecting the body against daily health chellenges.

Based on this testing, Maitake Gold 404® has been shown to be a consistent and potent immunostimulant.

Certification Exceeds Conventional Industry Standards

The biological assays provided under the ImmuneActive certification program offer customers a form of quality control that goes beyond the chemical analyses typically provided by companies, according to Roy Upton, herbalist and Planetary Formulas General Manager. "Most all comnpanies perform some type of quality control test," Upton said. "However, a biological assay measuring activity is often much better than chemical charaterization. Because of the important role Maitake plays in support of healthy immune system, it is important that activity, not just chemistry be delivered. People depend on its immune system activity, not its chemistry."

Endorsed by world's Premier Maitake Researcher

MaitakeGold 404® is the only Maitake extract endorsed by award-winning mushroom researcher, Dr. Hiroaki Nanba, PH.d. It was Dr. Nanba's research that led to the discovery of the beta glucan fraction known as MaitakeGold 404®.

MaitakeGold 404® is a trademark of the Tradeworks Group, Inc., and is protected under U.S. Patent # 5,854,404

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VitaNet ® Staff

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Date: May 09, 2005 06:10 PM
Author: Darrell Miller (dm@vitanetonline.com)

It's in the Blood

The National Cholesterol Education Program (NCEP) last July lowered the threshold for considering the use of statin drugs—a move which some say was motivated more by profits than scientific evidence. For example, the Center for Science in the Public Interest pointed out that eight of the nine authors behind the new recommendations had financial ties to statin manufacturers, which stand to reap billions of dollars more from a category that grossed $14 billion in the U.S. last year. And though the Food and Drug Administration (FDA) in January decided against authorizing over-the-counter (OTC) sales of statin drugs, drug companies would still like to see this happen.

“The medical establishment’s pushing of these drugs to becoming the number one category of prescribed drugs in the world has led them to keep lowering the total cholesterol number that triggers the drug recommendation,” said Neil E. Levin, C.C.N., D.A.N.L.A., nutrition educator, product formulator, and “Truth Advocate” for NOW Foods (Bloomingdale, IL), which produces a number of supplements for addressing cholesterol. “This is despite the lack of evidence that total cholesterol means much as regards cardiovascular risks.

“Other tests are much more important in terms of predicting risks, including CRP (C-reactive protein), the balance of different cholesterol fractions, and homocysteine,” he continued. “Add adult-onset diabetes to the risk factors for cardiovascular disease (CVD).”

At the same time, the allegation that enormous sales potential lay behind the lower threshold for prescribing statin drugs illustrates how widespread the problem of hypercholesterolemia (elevated total cholesterol) is. More than 100 million Americans have elevated cholesterol (total cholesterol values of 200 mg/dl and higher), and of these, more than a third have high cholesterol (levels of 240 mg/dl and higher), according to the American Heart Association. Those numbers have unfavorable implications for the incidence of CVD, as high cholesterol is considered a risk factor for coronary heart disease and stroke.

While statin drugs haven’t garnered the same degree of negative publicity that COX-2 inhibitors have suffered lately, safety concerns have arisen nonetheless. For one thing, these drugs lower the liver’s production of coenzyme Q10 (coQ10) along with its production of cholesterol. “CoQ10 is related to energy production and immune functions, is an antioxidant, and [is] an important cardiovascular nutrient,” Levin said. “It is not good to lower one’s coQ10 levels by half!”

Moreover, said Levin, statins increase the tendency of muscle tissues to break down. “Combined with inactivity or certain drugs, this can stimulate muscle wasting,” he said. “Muscle is where a good deal of calories are burned, so a loss of muscle could affect mobility and energy production, potentially adding to obesity problems. These muscle changes occurred in patients and persisted for years after treatment was discontinued, as shown by muscle biopsies, even if no obvious muscle problems were observed by the patients.”

And the last word on the subject may not have been spoken. Predicted Dr. Frank King, Jr. president of King Bio Natural Medicine (Asheville, NC), “Once the appropriate studies are finished, these drugs, along with hypertensives, will hit the fan bigger than the COX-2 inhibitors.”

Also looking toward the future, Levin said that of the 20 million Americans who will be “targeted” for statin drug prescriptions under the new NCEP guidelines, “Some of these will want to try natural methods first. Others will rebel at the side effects of the drugs and experiment with alternative products.”

King and Levin both saw opportunity for natural products in the fallout from drug safety concerns, with King projecting that sales of his company’s cholesterol-related homeopathic remedies will double in 2005. “The reports of deaths from drugs will always overshadow the trumped-up studies and news reports blasting dietary supplements,” said Levin. “Vioxx knocked vitamin E off the media’s radar screens pretty rapidly, though we still see ignorant reporters citing that [Johns Hopkins] vitamin E analysis as if it were true. But the comparable safety of supplements means that open-minded people will want to at least try natural therapies before signing in to a lifetime of drug therapies. Meanwhile, the studies on natural products will continue to build our credibility.”

Those studies keep coming in, with at least four major findings published in the past few months, plus a heart-health claim on walnuts authorized by FDA. They join a raft of earlier findings that link natural products—branded and otherwise—to healthy cholesterol levels.

"Blur of Products"

With so many natural alternatives to cholesterol drugs available, it can be hard to keep track. “As with any other category, the blur of products as they cascade over several shelves means that the retailer needs to have a good sense of what works and what they want to recommend to their customers,” Levin said. “Really, each person needs a protocol that would include antioxidants, fiber, vitamins, herbs, and oils. The pre-mixed cholesterol support formulas are a good starting place.”

To help retailers get a sense of “what works,” here is an alphabetical discussion of several nutrients that have demonstrated benefits in serum cholesterol levels. They include the following:

Barley may help lower cholesterol, according to a report in the American Journal of Clinical Nutrition (2004, vol.80, no.5: 1185-1193). Twenty-five adults with mild hypercholesterolemia consumed a controlled diet low in total fat, saturated fat, and cholesterol for 19 weeks. They then added whole-grain products containing barley to their diets that contained low (0 g), medium (3 g), or high (6 g) amount of beta-glucan per day for five weeks. Total cholesterol was reduced by 4 percent 9 percent, and 10 percent, respectively. The diet with the highest amount of beta-glucan led to a decrease in LDL cholesterol of 17 percent.

Chromium. There’s evidence, Levin said, that chromium in doses of 500 mg a day may decrease levels of low-density lipoprotein (LDL, the so-called “bad” cholesterol) and total cholesterol while raising levels of high-density lipoprotein (HDL, or “good” cholesterol). At the annual meeting of the American College of Nutrition last October, a poster presentation on the safety of Benicia, CA-based InterHealth Nutraceuticals’ ChromeMate niacin-bound chromium won first prize; among other things, the presentation cited chromium’s role in maintaining healthy blood lipid levels.

Fatty Acids. The latest in a long line of studies demonstrating the benefits of fatty acids in heart health is a study published in The International Journal of Clinical Pharmacology and Therapeutics in December 2004. It showed that docosahexaenoic acid (DHA), an omega-3 fatty acid, can restore normal blood vessel function in children with inherited high cholesterol. The study, which used Martek DHA produced from microalgae, concluded that restoration of normal blood vessel function has the “potential for preventing the progression of early coronary heart disease in high-risk children.”

“The evidence continues to accumulate on the cardiovascular benefits of DHA for people of all ages,” said Henry “Pete” Linsert, Jr., chairman and CEO of Martek Biosciences, an ingredient supplier based in Columbia, MD. “This study clearly indicates that DHA played an important role in healthy blood vessel function in the children in this study.”

On the Omega-Research.com Website maintained by fish oil manufacturer Nordic Naturals (Watsonville, CA) can be found summaries of several earlier studies linking omega-3 fatty acids to maintaining healthy blood lipid levels, as well as related benefits such as elasticity of the arteries. In a 2003 study published in the American Journal of Clinical Nutrition, it was found that women receiving a mixture of 4 g eicosapentaenoic acid (EPA) and DHA along with 2 g of gamma-linolenic acid (GLA) had lower levels of LDL cholesterol after 28 days compared to those who received either the EPA/DHA supplements without DHA, EPA/DHA with a smaller dose of GLA, or GLA alone.

Flax is another source of omega-3s, and Arkopharma/Health From The Sun (Bedford, MA) offers FiProFLAX in a variety of forms. Marketing director Hugues P. Mas said the flax is “QAI [Quality Assurance International] certified organic and guaranteed GMO [genetically modified organism]-free.” On its Website, the company offers a cholesterol quiz geared to consumers, discussing the importance of omega-3s as well as other nutrients.

Garlic. Adding to an already considerable body of research demonstrating that garlic can lower total cholesterol, LDL cholesterol, and triglycerides while increasing HDL cholesterol, researchers at UCLA in 2003 reported that Kyolic aged garlic extract reduced or inhibited plaque formation in the arteries of 19 cardiac patients taking statin drugs.

Lead researcher Matthew Budoff, Ph.D. commented at the time that the study “suggests that aged garlic extract may be a useful and beneficial dietary addition for the people who have high cardiovascular risk or who have undergone heart surgery.” Budoff has since presented several trade show seminars sponsored by Los Angeles-based Wakunaga of America, the makers of Kyolic.

Guggul. In use for centuries as a component of Ayurvedic medicine, guggul—a gummy resin tapped from the Commiphora mukul tree, which is native to India—has been studied since the early 1960s for its hypolidemic (blood-lipid lowering) properties. Sabinsa Corp. (Piscataway, NJ), an ingredient supplier which produces a standardized extract under the brand name Gugulipid, says the studies on guggul indicate that its hypolipidemic activity can be attributed to more than one mechanism of action.

Among the possible mechanisms are: inhibition of cholesterol biosynthesis, enhancing the rate of excretion of cholesterol, promoting rapid degradation of cholesterol, thyroid stimulation, alteration of biogenic amines, and “high affinity binding and anion exchange.”

Homeopathy. “Homeopathy activates the body’s own control system to work properly,” said King. “This is the safest and most curative approach to take.

“Forcing the body into biochemical change even naturally doesn’t actually have the curative action of homeopathy,” King continued. “Homeopathy can even correct the genetic predispositions to disease we may have inherited from as deep as a thousand years into our family chain.” King Bio makes Artery/Cholesterol/BP, a homeopathic formula intended to help tone heart muscles and blood vessels.

Low glycemic index foods. In a study published in the February issue of the American Journal of Clinical Nutrition, researchers found that high glycemic load is negatively correlated to serum levels of HDL cholesterol. Assessing the relationship between blood levels of lipids and diet in a test population of 32 healthy males and females ages 11 to 25, the researchers found that glycemic load accounted for 21.1 percent of the variation in HDL cholesterol. They concluded that glycemic load appears to be an important independent predictor of HDL cholesterol in youth and noted that dietary restrictions without attention to glycemic load could unfavorably influence blood lipids.

Medicinal Mushrooms. Although its product SX-Fraction is intended primarily to address high blood sugar, Maitake Products, Inc. (MPI, Ridgefield Park, NJ) found in a clinical study that LDL cholesterol in diabetic patients declined modestly (from 142 mg/dl to 133 mg/dl) over a two-month period. Those taking SX-Fraction also lost about 7 lbs. in the same time period.

“The more impressive lowering of cholesterol, however, comes from the dietary fiber that is found in all medicinal mushrooms,” said Ellen Shnidman, manager of scientific affairs at MPI. She cited animal studies which documented the cholesterol-lowering properties of four different mushrooms: Maitake, shiitake, agaricus, and enokitake.

For example, a study reported in the September 1996 issue of Alternative Therapies showed “a 44 percent reduction in total cholesterol in rats consuming Maitake mushroom in their diet,” said Shnidman. “This cholesterol reduction is accompanied by weight loss, relative to rats eating a similar high-choelsterol diet without mushrooms. Apparently, cholesterol is excreted by the rats in sufficient quantity to aid in weight loss.”

Oat bran. A 2004 consumer study conducted by the Natural Marketing Institute (NMI, Harleysville, PA) for Nurture, Inc. (Devon, PA), which produces the ingredient OatVantage, found that 63 percent of consumers managing their cholesterol levels prefer oat-based ingredients.

Oat bran is the subject of a health claim authorized by FDA in 1999, and NMI research found that 69 percent of respondents preferred the FDA-permitted health claim, “Helps Lower Cholesterol,” over the model structure-function claim, “Helps Maintain Healthy Cholesterol Levels.” “This is significant for food, beverage, and dietary supplement manufacturers who want to increase sales by using a more consumer-desired claim on the product label,” said Griff Parker, Nurture CEO.

Plant sterols. Also the subject of an FDA-approved claim for heart health, plant sterols (structurally similar to cholesterol in humans) can block the absorption of cholesterol, according to a number of studies. In an “Ask the Doctor” publication (available online at www.atdonline.org), Decker Weiss, N.M.D. noted that sterols enter the same receptor sites that cholesterol enters on its way to the bloodstream. “The cholesterol, being blocked from absorption, remains in our intestines where it is eventually excreted,” Weiss wrote. General Mills has just introduced Yoplait Healthy Heart, a yogurt high in plant sterols.

Policosanol. A mixture of fatty alcohols derived from sugar cane or beeswax, policosanol has been favorably compared in clinical studies to several types of prescription drugs for managing cholesterol. On its own, policosanol was found in a 1999 study to reduce LDL cholesterol while raising levels of HDL cholesterol.

Probiotics. “Several studies have indicated that consumption of certain cultured dairy products resulted in reduction of serum cholesterol, as well as triglycerides,” wrote Dr. S.K. Dash, president of probiotic manufacturer UAS Laboratories (Eden Prairie, MN), in his Consumer Guide to Probiotics. Among other studies, Dash cited two controlled clinical studies from the VA Medical Center at the University of Kentucky.

“In the first study, fermented milk containing [Lactobacillus] acidophilus was accompanied by a 2.4 percent reduction of serum cholesterol concentration,” he wrote. “In the second study, a different L. acidophilus strain reduced serum cholesterol concentration by 3.2 percent. Since every 1 percent reduction in serum cholesterol concentration is associated with an estimated 2 to 3 percent reduction in risk for coronary heart disease [CHD], regular intake of fermented milk containing an appropriate strain of L. acidophilus has the potential of reducing risk for [CHD] by 6 to 10 percent.”

Dash said his company’s DDS Probiotics contain DDS-1 L. acidophilus, “which has been researched and demonstrated to show cholesterol-lowering effect.”

Psyllium. “Internal cleansing is very important” in maintaining healthy cholesterol levels, “especially if you do it with a lot of fiber,” said Sunil Kohli, vice president of Chino, CA-based Health Plus, Inc. The cholesterol-managing ability of fiber in general and psyllium in particular is “very well-established,” he said.

However, Kohli said, “It will probably do you no good if it’s random. It should be done on a regular basis, and it should be supervised. Consulting the doctor or pharmacist is important.”

Soy. The protein in soy “has evidence of lowering total cholesterol and LDL cholesterol, based on reviews of studies using over 20 g of soy protein per day,” said Levin. “Soy isoflavones are considered only partly responsible for this effect.”

Sytrinol. A patented proprietary formula derived from natural citrus and palm fruit extracts and containing citrus polymethoxylated flavones and palm tocotrienols, Sytrinol has been shown in clinical trials to improve total cholesterol, LDL cholesterol, and triglycerides by up to 30 percent, 27 percent, and 33 percent, respectively. Having just wrapped up Phase III of a long-term trial of Sytrinol, Chicago-based SourceOne Global Partners, which owns the exclusive worldwide license for intellectual property associated with the ingredient, is commencing a study that combines Sytrinol with plant sterols.

Tocotrienols. On its Website discussing the science and benefits of tocotrienols (www.tocotrienol.org), ingredient supplier Carotech Inc. (Edison, NJ) identifies several benefits for blood lipid levels. Tocotrienols, according to the Website, have been shown to “inhibit cholesterol production in the liver, thereby lowering total blood cholesterol;” “[suppress] hepatic HMG-CoA reductase activity [and result in] the lowering of LDL cholesterol levels;” and “inhibit cholesterogenesis by suppressing HMG-CoA reductase.”

New Weapons

There are also nutrients that are emerging as potential weapons in the fight against cholesterol. Levin cited rice bran oil, resveratrol, pantethine, l-carnitine, and niacin as showing promise.

With all of this, Levin said, it’s important for retailers to remember that “they are not allowed to discuss diseases and remedies unless there is an approved FDA health claim allowed on the label, as with soy protein and plant sterols. What is allowed are structure-function claims such as ‘cholesterol support,’ ‘promoting normal, healthy circulation,’ ‘homocysteine regulators,’ etc.”

Supplementation is only one tool for managing cholesterol levels, manufacturers pointed out. “Besides nutrition, lifestyle is a key to controlling cholesterol,” Levin said. “Eating a variety of antioxidant-rich foods will prevent the liver from churning out cholesterol as a ‘cheap’ antioxidant. The body uses oxidized cholesterol to patch leaky and damaged blood vessels, so the ability to build healthy collagen is a must, using nutrients like vitamin C, Pycnogenol, rutin, hyaluronic acid, and MSM.

“Don’t forget exercise and stress reduction,” he added. “Stress results in high cortisol levels—usually accompanied by poor blood lipid levels—and a lack of good sleep to produce unhealthy people.” VR

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