Search Term: " Sca "

	Where in the world is cannabis legal?	Darrell Miller	6/22/18
	Peruvian Maca	Darrell Miller	9/17/14
	Activated Charcoal - Highly absorbent material to combat poisoning	Darrell Miller	4/24/08
	Lutein: A Plant Pigment That Provides Protection From The Sun	Darrell Miller	10/23/07
	Exotic Herbs From The Amazon Basin	Darrell Miller	6/22/07
	NHA/Washington Update - Statistics Lie	Darrell Miller	4/6/07
	Fruit and Vegetable Lightning drink mixes from Natures Plus	Darrell Miller	2/6/07
	Benefits - Supports joint function and tissue health*	Darrell Miller	12/11/06
	Preventing Chronic Health Problems with AHCC	Darrell Miller	10/26/05
	Benefits of Total Daily Formula	Darrell Miller	10/13/05
	Re: Magnesium	Darrell Miller	10/6/05
	Assists Digestion of Proteins, Carbohydrates and Fats	Darrell Miller	9/3/05
	Curcumin - Turmeric Extract	Darrell Miller	8/19/05
	Fats and Oils: Clearing the Confusion	Darrell Miller	6/21/05
	Fats for Life - the quality of the fat you eat is probably much more important than the...	Darrell Miller	6/12/05
	Re: Keeping the Intestines Healthy	Darrell Miller	5/12/05
	Re: Its in the Blood	Darrell Miller	5/9/05

Date: June 22, 2018 08:10 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Where in the world is cannabis legal?

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Date: September 17, 2014 05:25 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Peruvian Maca

What is a Maca Root?

Maca Root is one of the roots and tuber harvests of higher protein content. Until late years, this nutritious base of the Andes was little or nothing known for the lion's share of the individuals thereof, Peru (aside from the tenants of the Andes) and obviously overlooked by whatever is left of the world.

Maca (otherwise called Peruvian Maca or Maca Andina) has an astonishing quality to develop to remarkable statures: from 3800 to 4800 meters high in the most cold Andes mountains, where temperatures are amazing, from exceptional hotness morning to ice on the night, frigid winds, snow and persevering high power of daylight. In this antagonistic region, where there is little oxygen, there is uncommon vegetation develop just potatoes and maca sharp. There are no trees, no plants, just a couple of centimeters tall.

This tuber, irrelevant part of the tuberous root size and state of a typical radish, is effectively dried under the sun and keeps up its nutritious qualities, with elevated amounts of iron, for a few years stockpiling. It is brilliant nourishment and Incas additionally utilized it for its richness improving activity and its impact on sexual conduct.

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Date: April 24, 2008 02:44 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Activated Charcoal - Highly absorbent material to combat poisoning

Activated charcoal has been treated by heat to open up millions of small spaces between the carbon atoms and turn it literally into an atomic sponge that adsorbs both organic and organic impurities.

This heat treatment is carried out in the absence of oxygen, so the charcoal cannot burn. Instead, what oxygen it did contain is driven off leaving behind all of these interstitial gaps that multiply the effective surface area by factors of ten. Since it is the surface area of the charcoal that determines its potency, then the greater this is the better.

Activated charcoal has a massive surface area, and just ten grams has the same surface area as nine American football pitches or 77 tennis courts. Ten grams is just marginally more than a third of an ounce. The term adsorb has a different meaning to absorb, and while a real sponge absorbs water by mopping it up through capillary action and suction, activation carbon adsorbs substances through a form of chemical attraction. You get rid of water from the sponge by squeezing it, but that doesn’t work with activated charcoal, since the substances are bound to it, not just physically constrained.

This huge surface area provides activated charcoal with innumerable bonding sites, and when chemicals that are attracted to carbon pass by they are attached to the surface. They cannot get free again, as water in a sponge can, but are bound to the surface of the carbon. Because the digestive system has no effect on charcoal then whatever is bound to it passes naturally through the body.

It is most effective at binding other carbon-based materials, and other substances with the right electronic arrangement, but others will just pass straight through. Because it is a chemical process, once all of the empty bonding sites have been taken up, the charcoal loses its effectiveness and has to be replaced. It is possible to regenerate it, but hardly worthwhile for you to do so because of the small quantities you use.

Because of the way it works, activated charcoal can help people to recover from some forms of food poisoning. It can adsorb gases in the intestine and help to relieve the pain of excessive gas in the gut. It has many additional uses that will be touched on later, but for now we will look at its effect on poisons because that is where activated charcoal is of greatest benefit to us.

It does not adsorb and neutralize all poisons, but is very effective with those that it can be sued for. Professor Touery proved a point when he drank a lethal dose of strychnine in front of colleagues at the French Academy of Medicine in 1831 and came through unScathed. He had mixed the strychnine with activated charcoal, and the fact that he lived after drinking a dose that would certainly have led to a very painful death within minutes testifies to the powerful effect of activated charcoal as an potential antidote for poisoning.

Ever medicine cabinet should have an emergency supply of activated carbon, especially those with young children in the household. However, this is not good news for the pharmaceutical companies who have reacted by refuting some of the claims made in its favor: they have claimed that it is not effective against arsenic. If that is so, then how did Michel Bertrand survive after swallowing 5 grams of arsenic trioxide – 150 times what is regarded as the lethal dose? He did this is 1813 after mixing it with activated charcoal, just as Professor Touery was to do 18 years later with ten times the lethal dose of strychnine.

It is true, however, that it does not have this degree of activity with all poisons, and it has no effect on cyanide, alcohols, antifreeze (glycols) and lithium. It also has no effect on corrosive poisons such as the strong alkalis used in oven clearers, or hydrocarbons such as kerosene. The way it works is adsorb the poison and prevent it being released into the body. For that to happen, the poison must have an affinity for carbon, and its adsorption site, and not all substances possess that property. Those that do however are permanently bound and therefore safe.

For charcoal to be effective in neutralizing a poison, it must be swallowed within an hour of taking the poison, or the poison will be too far advanced ion the digestive process for the charcoal to do any good. Keep in mind, though, that it is not selective, and activated charcoal can adsorb nutrients and other beneficial constituents of your body’s chemistry. It is important therefore that you take in only when necessary: you might need several doses if the poison was severe, but once it has done its job it is not meant to be used as a maintenance material to take ‘just in case’. Used like that, it can do harm.

If charcoal can adsorb poisons then it makes sense to believe that it can also adsorb some of the harmful agents that cause food poisoning. Not all food poisoning of course, but certainly those organisms that emit toxins that are attracted to carbon. And this is, in fact, the case. Food poisoning is caused by bacteria rather than viruses, and is not the presence of the bacteria that make you vomit and feel very ill.

As bacteria grow in your body they release toxins, or poisons, into your digestive system. These poisons are what make you ill. They can seriously affect the complete gastro-intestinal tract, causing vomiting, diarrhea, and inflammation and swelling of the small and large intestine. The latter can cause abdominal cramps and severe colic, and the severity of the symptoms depends very much upon the type of bacteria and the number of them in your body.

Many of these toxins are attracted to carbon since they are frequently organic based, and activated charcoal can be used to adsorb them. Once adsorbed they lose their potency, and since carbon is not digested by the body, they are passed harmlessly through the colon and eliminated in the faeces. It can also be used to eliminate many other foreign bodies from your gut, including viruses and fungi and might possibly reduce the concentration of uric acid, which can bring relief to gout sufferers.

Activated charcoal has many uses, and is normally available in capsule form. It can be dangerous to take too much, particularly if you suffer from intestinal problems that cause constipation, because the charcoal itself can have that effect. However, there is no better emergency treatment for accidental poisoning in the home, although, since it is not suitable for all poisons, you must still regard poisoning as an emergency and contact the emergency services.

Activated charcoal, or activated carbon as it is sometimes called, is also a good emergency treatment for vomiting and the other unpleasant effects of food poisoning. It deals with bacterial toxins in the same way as any other, though once again you must refer to your physician before or after using it – preferably the former.

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Date: October 23, 2007 10:00 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Lutein: A Plant Pigment That Provides Protection From The Sun

Lutein is a plant pigment, and protects protection from the sun needed to prevent damage to the skin and eyes from its strong ultra violet (UVB) radiation. Lutein is a carotenoid and strong antioxidant that is found in red, yellow, orange and dark green fruit and vegetables such as broccoli, curly and sea kale, spinach, carrots peppers and squashes. It is also available from egg yolks, corn and some fruits such as pomegranates. It is the colored pigments, especially the reds, yellows and oranges, in which lutein is most found.

Lutein can also prevent cataracts and provide benefits for age related macular degeneration. However, before discussing the benefits, it is necessary to discuss exactly what these conditions are and what causes them. Let’s have a heads up on cataracts first.

A cataract takes the form of a clouding of the lens of the eye that leads to blurred vision and eventual virtual blindness when the cloudiness is extreme. It is not blindness due to problems with the nerves of the eye, but due to the lens become cloudy, and Scattering light entering the eye. It is not a film over the eye as many people believe, but a cloudiness of the lens, and cataracts can normally be treated by removing the whole lens and replacing it with a lens implant – or a synthetic lens.

It is not fully understood how lutein can help cataracts, but studies have shown that those take a large quantity of lutein in there diet have up to 50% less chance of getting cataracts that those that do not. It has also been demonstrated that men who ate broccoli and spinach regularly had a 25% less chance of getting cataracts. The same is true of those that include a lutein supplement of around 6 mg daily, although up to 20 mg is considered an effective dose.

However, it not only through its properties in protecting against cataracts that lutein can help to preserve the health of your eyes. It is also through its effect on macular degeneration. The macula is small part in the center of the retina that allows you to see central vision in high detail, especially close up when you use the center of your eye. Age-related macular degeneration, known as MD, affects your macula so that you can see fine round the edges, but your central vision is blurred. It is therefore difficult to drive, read or carry out tasks that need good central focus. You will find it next to impossible to thread a needle for example. It can come on very slowly, in fact so slowly that you never notice it because the change from day to day, or even week to week, is so small.

It is not coincidence that lutein is concentrated in the macula, and that a lutein supplement can help to prevent macular degeneration. Lutein is believed to filter out some of the blue wavelengths of light, and it is the blue wavelengths that are though to cause free radical damage and oxidative stress to various organs of the body exposed to light, but specifically the eyes. That is why it is believed that lutein helps to prevent macular degeneration, and studies have indicated a good supplement to consist of up to 30 mg each day.

It can also protect the skin from damage by UV radiation, and also prevents free radical damage to skin cells causing premature aging of the skin. The latter occurs through its antioxidant properties, while the former is because if its light filtering properties. It can not only filter out the blue light that can cause macular degeneration but also ultra-violet radiation that affects the skin and can cause skin cancer. There is a fine line between the blue and ultra violet wavelengths from sunlight, and both can contribute to certain medical conditions. However, the absorptive properties of lutein are such that it can absorb the more harmful of these.

The antioxidant properties of lutein are important in their own right, and can help to reduce cholesterol deposition in arties and help to maintain a healthy arterial wall thickness. The same is true of any carotenoids that reduce heart problems, some cancers, especially of the cervix, stomach and lungs, and others that can be caused by free radical action and narrowed arteries such as strokes and brain hemorrhages.

Although it is not one of those supplements considered essential, lutein is biologically essential in that it cannot be produced by the body. It has to be taken through the diet. There is no specific recommended daily allowance (RDA) because life can go on without it, but it does play a role in your everyday health.

However, the average person has a lutein intake less than that needed to take advantage of its UV protection or antioxidant effect. As previously stated, the effective dose is considered to be 30 mg daily, and the average American intake is about 2 mg. That’s an awful lot of egg yolks or tomatoes you are going to have to eat! If you do intend to take your lutein from the natural source, then it much more easily assimilated into your body if not overcooked. Lightly steaming is the best way to prepare your vegetables for maximum nutritional effect.

You can also take lutein as a supplement in the form of tablets, creams and drinks, and can also be found in other supplements that contain carotenoids such as lycopene and beta-carotene. Although not consider essential to life, do not underestimate the health benefits to be gained from a diet high in lutein, especially if you value the health of your eyes.

All strong antioxidants provide you with health benefits due to their ability to destroy the free radicals that in turn destroy the DNA in your body cells, and disrupt the cells themselves. Combine that with their action as filters to the damaging rays of the sun and you have in lutein a plant product that is far reaching in the health benefits that it can provide you with. If you are looking for a lutein supplement, stop into your local or internet health food store for lutein is an over the counter supplement.

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Buy Lutein at Vitanet, LLC ®

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Date: June 22, 2007 05:07 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Exotic Herbs From The Amazon Basin

Although many traditional herbal medicines have yet to find complete scientific corroboration in the West, it follows logically that people wouldn't use an herbal product for centuries if it didn't work.

Many of the popular herbs we all recognize as having great health benefits were only recently considered pretty exotic. Even green tea - a staple in China for centuries -has only lately gone main stream.

So it will likely be with herbs from the Amazon basin and its environs. The Amazon basin is one of the most bountiful environments on the planet. Explorers and botanists from the West have looked to this region for generations for the "next big thing." Of course, in many cases, the "next big thing" has already been in use for centuries.

In this issue of Ask the Medicine Hunter, we're going to look at some energizing and life- stimulating herbs that also happen to have great antioxidant properties, too. Best yet, many of them are available to us here from companies that practice fair trade policies.

Let's take a look at some of the herbal powerhouses coming out of the Amazon (and its nearby neighborhoods):

Maca (Lepidium meyenii) has been cultivated for a long time at least 2000 years. Related to brassica family plants like radishes, mustard and cabbage, its foliage does actually look somewhat radish-like, but grows close to the ground.

Maca is cultivated by the Andean people in Peru's central highlands, and contains a plethora of beneficial compounds that enhance overall health and vitality. The tradition of cultivating maca is an old one some strains have been found in Incan sites that date from 1600 B.C. During early European colonization, maca was used by the local native culture as a form of currency, much of the way cocoa was used by the Aztecs, further north in pre-Columbian Mexico.

Maca thrives in high altitudes - between 10,000 and 16,000 feet. The harsher the conditions, the better it grows, or so it seems. In fact, efforts to grow the plant in Central Europe haven't been as successful - maca seems to enjoy its home turf the best. In Peru, maca is a popular and beloved nutrient-packed superfood, and is commonly powdered and mixed into drinks at roadside stands throughout the Andes.

Q. I've heard of maca being used for healthy libido - are there any other benefits?

A. Maca is a natural energizer, and although it is recognized for it's libido enhancing abilities, it has other uses, too, acting as an adaptogen - similar to rhodiola or ginseng. In fact, in South America, maca is known as "Peruvian Ginseng." Though maca is not ginseng at all, some of the benefits of both plants are similar.

In any event, maca is recommended for boosting the immune system, menopause support, and hormonal balance in general. For daily use, maca is most recognized as a great source of energy and all-day endurance. Alkaloids from maca root may be partially responsible for both maca's energizing and libido boost. Research shows that maca affects the hypothalamic-pituitary (HPA) axis - boosting energy and overall aphrodisiac prowess in men and women. Maca contains novel compounds called macamides and macaenes, which have been proven in animal studies to significantly enhance energy, stamina and sexual function reasons people have been so consuming maca for 2000 years.

There are other serious reasons why maca is such an excellent plant. One group of compounds in maca is the isothiocyanates-aromatics constituents that are responsible for the "hotness" of mustards and radishes - fellow members of the brassica family. Isothiocyanates from other members of the brassica family may reduce the risk of breast and stomach cancer. Although the same constituents specifically from maca haven't beentested, it's plausible that they could have the same effects.

Q. I've heard a little about guarana extracts - is it just caffeine?

A. Guarana is widely loved for its mild stimulating effect, which is due to caffeine. But this is by no means this Amazonian herb's sole beneficial compound. Guarana (Paullinia cupana) is so logically ingrained in the culture of Brazil that it's practically a rival (actually out-sells) Coca-Cola in its soft-drink form. Like many other indigenous herbs, guarana was in use locally well before European settlement. Its Latin name comes fromthe German botanist C.F. Paullini, who first encountered the herb in the 1700s. This evergreen vine typically climbs fairly far up the Brazilian forest trees. The seed is the part that gets used. In one clinical study, guarana boosted the memory alertness of participants, even when the caffeine level per dose was a low 9 mg., as compared with approximately 100 mg for a cup of coffee. This effect suggests that other agents than caffeine contribute to a feeling of well being.

Guarana also contains powerful antioxidants including catechin, epicatechin and proanthocyanidins, which protect cells against destruction from free radicals, and impart benefits to the body's tissues and blood. The small seed of this plant is powerful in its health benefits.

Catuaba Bark:

Catuaba (Erythroxylum catuaba) is a common tree found in South America from Brazil to Peru, in the same genus as the coca plant. Catuaba contains components known as alkaloids. These alkaloids (called catuabine A, B, and C) are probably responsible for themental boost most people get when they take catuabe-based supplements or mixes.

There may be little confusion regarding catuaba, because various species and genus typesuse the common name. As a result, "catuaba" gets bandied around a lot, and one person'Scatuaba may not be the next. Read labels carefully. The catuaba I've had the best luck with is Erythroxylum catuaba.

Coffee Fruit:

One of my favorite drinks in the world is coffee, and I'm sure at many people reading thisconsider it the essential part of their morning, too.

The part of coffee that we use the most is the seed of the coffee fruit - which appears as a bright, red berry. Most of the time, this fruit is sloughed off and left behind in the process of making coffee - it's really too delicate to last long in hot conditions.

But advances in technology have tapped a previously diScarded resource. Though the fruit of coffee is available in any coffee-growing economy, a high antioxidant commercial extract of "coffee cherry" is now available from the fruits of coffee plants in Mexico.

Coffee fruit has many of the attributes of other dark-colored, anthcyanin-rich fruits. Coffee fruit (also referred to as "coffee cherry") appears not to be just another antioxidant, however. Current research on this once-forgotten, former castoff shows impressive abilities to decrease tumor size, and possibly even prevent their formation in the first place. It seems that the elements in coffee berry activate T-lymphocytes in such a way that mammary tumors are shrunk or simply put on hold. It will be fascinating to see how this science plays out.

Muira Puama Bark:

Muira puama (Ptychopetalum olacoides) grows between 15 to 45 feet high. Native to theAmazon basin of Brazil, the dried bark has been used for centuries as a traditional energysupport. Components include beta-sitosterol, campesterol and lupeol.

Muira puama, like other central nervous stimulants has been researched lately for its ability to boost memory retrieval and protect neural (brain) tissue. Who knows? Maybe this traditional ingredient could someday be on the cutting edge of natural medicines fighting Alzheimer's, much the way green tea and turmeric are currently. In one unpublished French study of 262 men with low libido and poor erectile function, 62% experienced significant improvement after taking an extract of Muira puama for two weeks.

Acai Berry:

Acai (Euterpe acai) berry is a traditional favorite (and readily available) food source for people in the Amazon. The tree is a tall-growing palm with berries that provide - a rich source of anthocyanins, potent purple pigments with extraordinary high antioxidant activity.

Once harvested, acai fruits decay rapidly. As with coffee fruits, special processing is the surest way to make certain the nutrients of acai berry make it to those of us outside the Amazon basin.

However, these wonderful fruits not only fight against free radical damage, but help our natural digestive enzymes and boost natural immune defenses, too. In fact, current research is investigating whether compounds in acai may have a fighting effect on leukemia, too. So far, the results have been very positive.

Look for supplements made using organically-grown, fair trade acai berry. The best companies ensure that the local people harvesting acai and the communities where they live gather more than just short-term benefits. The best companies work not just to provide jobs, but better lives for generations to come.

Q. What is sustainability and fair trade, anyway?

A. Sustainability refers to a set of naturally occurring circumstances, or intentionally designed practices and principles, which ensure that all parts or members of a situation are adequately nourished to promote their healthy continuance. In current parlance, sustainability often refers to practices and programs designed and implemented to keep natural systems healthy and flourishing. Many such programs focus on environmental protection and preservation of traditional cultures. In the world of medicinal plants, sustainable practices include organic agriculture, species management, fair trade, and benefit-sharing programs.

In other words, sustainability pays people fair wages, puts resources back into their communities, and ensures that the resources that benefit us all are going to be around for a long time. It is an earth-friendly, people-friendly concept of commerce that happily, is taking root around the world.

Conclusion:

The traditional cultures that use - and have used - these ingredients for generations wouldn't have done so if they hadn't been effective. Fortunately we live in an era when formerly locally-used herbs are now available far beyond their previous range. We are also fortunate to have companies and individuals working hard to make sure that the people who tend and care for these precious resources are paid fairly for their efforts, andthat their families and communities benefit from this commerce as well.

The great thing about using traditional herbs and ingredients that have been gathered in this manner is that you know they'll be around for a long time.

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Exotic Herbs at Vitanet

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Date: April 06, 2007 04:57 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: NHA/Washington Update - Statistics Lie

The mass media targets antioxidants with misleading stats.

The smear campaign against nutritional supplements continues in 2007, with headlines such as the following: “Antioxidants Don’t help You Live Longer,” “Antioxidants Might be Dangerous,” “Antioxidants Do Not Prevent Disease and May Increase Mortality.” Do you notice a theme? Antioxidants are the latest target for media manipulators seeking to steer the public away from life-enhancing nutrition.

The study that spawned these alarmist headlines, first published in the Journal of the American Medical Association, is a “meta-analysis”; this means it draws its conclusions from a number of different studies. In this case, 68 studies involving 232,606 people were analyzed. Meta-analyses are an example of how easily statistics can lie.

Deception Exposed

Like 2004’s infamous vitamin E-bashing meta-analysis (which proclaimed vitamin E to be deadly, even though it focused on elderly patients who were already stricken with disease), the recent meta-analysis of antioxidants has a preordained outcome—results are determined by which studies are chosen for analysis. Experts have pointed out significant flaws in the execution of this meta-analysis; for example, it includes studies that administered many different combinations of antioxidants, and in varying doses. In addition, these Hitler-skelter antioxidants and dosages are Scattered across a wide range of people, everyone from male doctors to elderly nursing home patients. Finally, this meta-analysis neglected to include the most significant antioxidant study ever conducted in its findings. The china study, which in surveying 800 million people was one of the most comprehensive studies of its kind, verified antioxidants effectiveness in fighting cancer, heart disease and stroke. Why was it not included in the meta-analysis?

Even a junior high school science student would question this meta-analysis’s statistical significance. So how can mass media transform this flawed study into headlines that proclaim antioxidants will kill you?

The answer is because the media gets away with it. In our fast paced world, where celebrity rehab stints are front page news, fact-driven journalism is fading—and distracted news readers are enabling its demise. The solution? Consider media reports with awareness and intelligence, and never assume that headlines speak truthfully.

The recent antioxidant bashing study crumbles when subjected to awareness and intelligence. In addition to the obvious study flaws, and even more telling: stories coving the study with headlines proclaiming “antioxidants may increase mortality” are grievously misleading; as it turns out, the study did not identify any causes of death—which were surely diverse given that the study tracked over 200,000 diverse people. Believe the headlines, however, an antioxidants causing all the deaths when in fact they probably caused none—an example of the absurd “association with out causation” logic that may destroy our right to take safe, natural supplements.

Continue investigating and you will find that Denham Harman, MD, PhD, the “father of the free radical theory of aging,” antioxidants pioneer and professor emeritus at the University of Nebraska Medical Center, is able-bodied and active at age 91. Harman takes antioxidants vitamin C, vitamin E and selenium daily—a revelation with more credibility than any antioxidant bashing hatchet-job study.

Educate yourself about antioxidants and other supplements that Congress is trying to take away from you. Fight to keep your health under your own control, always. Patronize the natural health food store that are committed to providing you with quality products and reliable knowledge. For more information, visit www.nha2007.com

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Date: February 06, 2007 02:41 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Fruit and Vegetable Lightning drink mixes from Natures Plus

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Buy fruit and Vegetable Power drink mixes at Vitanet

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Date: December 11, 2006 03:46 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Benefits - Supports joint function and tissue health*

To understand glucosamine's role, it is important to understand joint structure and function. Cartilage in the joints acts as a shock absorber to cushion the blows of daily wear and tear. Joint cartilage is made of a unique connective tissue that consists of collagen and proteoglycans. Collagen is a strong, fibrous, insoluble protein. Proteoglycans are large, carbohydrate-rich protein chains made up of 95 percent polysaccharides and 5 percent protein called glycosaminoglycans (GAGs). GAGs are composed of repeating two-sugar units (disaccharides) that contain glucosamine sulfate and other amino sugars. Surrounding the joint cartilage is synovial fluid, which contains many substances including its chief component, hyaluronic acid. Hyaluronic acid forms the backbone of other proteoglycans and is responsible for the thickness of synovial fluid as well as its lubricating and shock-absorbing properties. Synovial fluid also provides nutrients for the joint cartilage.

Glucosamine sulfate is a normal constituent of glycosaminoglycans in cartilage and synovial fluid. In essence, glucosamine sulfate provides important building blocks for cartilage production. Laboratory studies suggest that glucosamine may also function to stimulate production of cartilage-building proteins. It is also thought that the sulfate portion of the molecule contributes to the efficacy of glucosamine sulfate in the synovial fluid by providing the elemental sulfur needed for strengthening cartilage and aiding glycosaminoglycan synthesis. 1,2,3

Glucosamine sulfate has been the subject of research for over twenty years. Clinical trials as well as experimental studies have repeatedly supported the efficacy of oral glucosamine sulfate in supporting joint function. In one large open trial, over 1200 people took oral glucosamine sulfate for periods ranging from 36 to 64 days. In this multi-center trial, ninety-five percent of the subjects experienced greater joint comfort and increased mobility. The physicians reported "good" results in 59%, and "sufficient" results in 36%. Furthermore, the improvements in joint health lasted for up to three months after the glucosamine sulfate was discontinued. 3

Promotes optimal joint comfort, function and flexibility*

Boswellia serrata (Indian frankincense) has been used for centuries in the Indian Ayurvedic system of medicine to maintain healthy joints. Even today, this is one of the primary uses for this plant in Ayurvedic medicine. Boswellic acids have been shown to support healthy joint tissue, maintain circulation to joints, enhance joint mobility, and promote joint comfort in animal models without known side effects. 4

Boswellin® is an extract rich in boswellic acids. Boswellic acids are potent modulators of enzymes involved in leukotriene synthesis in vitro, promoting a healthy balanced production of these components of the immune system.5 Healthy leukotriene balance can lead to enhanced joint function. A human clinical study was conducted to assess the effects of supplementation with a formula containing Boswellia, Curcumin and other nutrients on joint function. In this double-blind placebo-controlled crossover trial, participants were randomly assigned to receive the herbal formulation or a placebo for 3 months. Following this 3-month period, the treatments were reversed for an additional 3 months. The results showed that while each group was receiving the herbal formulation, they had superior joint function and a greater sense of joint comfort when compared to the placebo groups.6 Other trials lend further support to Boswellia’s ability to promote healthy joint function.4,6,7

Curcumin is a potent antioxidant that has known free radical Scavenging activity. This activity of Curcumin is thought to play a major part in its role as a joint protective nutrient. In fact, the numerous beneficial effects attributed of whole turmeric are thought to stem in large measure from the antioxidant properties of curcuminoids. Antioxidants neutralize free radicals, which are highly unstable molecules that can damage cellular structures through abnormal oxidative reactions. Curcumin is not toxic to cells, even at high concentrations. Pure Curcumin was shown to be less protective than a mixture of curcuminoids, indicating a possible synergism among the curcuminoids.8

Curcumin demonstrates several other in vitro effects linked to free radical Scavenging. Curcumin Scavenges nitric oxide, a compound associated with the body’s inflammatory response.9 Curcumin also demonstrates in vitro inhibition of certain enzymes involved in promoting inflammatory reactions in the body. Together these results strongly suggest that Curcumin is a potent bioprotectant with a potentially wide range of therapeutic applications.9,10,11

Preliminary human trials have assessed the therapeutic potential of Curcumin, with results that verify the traditional use of turmeric as an herb to enhance joint health. In a short-term double-blind, cross-over, comparative study, eighteen people were randomized to receive Curcumin (1200 mg daily) or an alternative therapy for two-week periods. The participants in the Curcumin groups were shown to produce measurable enhancements in joint flexibility and walking time.12 Research suggests that Curcumin and Boswellia work extremely well in combination to benefit joint health and mobility, as trials combining both nutrients have yielded highly positive results.

Bioperine-Nature’s Absorption Enhancer Boosts Nutrient Absorption*

Traditional Ayurvedic herbal formulas often include black pepper or long pepper as synergistic herbs. The active ingredient in both black pepper and long pepper is the alkaloid, piperine. Experiments carried out to evaluate the scientific basis for the use of peppers have shown that piperine significantly enhances bioavailability when consumed with other substances.13 Several double-blind clinical studies have confirmed that Bioperine® increases absorption of nutrients.14

Curcumin is known to be poorly absorbed in the intestinal tract when used on its own, thereby limiting its therapeutic effectiveness. Oral doses are largely excreted in feces, and only trace amounts appear in the bloodstream. However, a study has shown that concomitant administration of 20 mg of piperine with 2 grams of Curcumin was able to enhance Curcumin bioavailability by an astounding 2000%. 15 These results speak to the wisdom of including a small amount of Bioperine® in the formulation to ensure nutrient bioavailability.

Sustained Release – For lasting joint comfort and convenient dosing

To ensure that the body can utilize all of the joint health-enhancing nutrients effectively, Best Joint Support featuring ArthriBlend-SR™ has been designed to have a sustained release delivery system. The nutrients are released over a longer period of time, maximizing absorption and providing the comfort-enhancing properties in a sustained manner. This unique delivery system allows the product to be taken just twice daily while maintaining its efficacy throughout the day.

Safety

Suggested Adult Use: Take two tablets every 12 hours. Take 4 tablets daily.

Scientific References
1. Vidal y Plana, R.R., Bizzarri, D., Rovati, A.L. Articular cartilage pharmacology: I. In vitro studies on glucosamine and non-steroidal antiinflammatory drugs. Pharmacological Research Communications 1978; 10(6):557-569.

2. Tapadinhas M.J., Rivera, I.C. Bignamini, A.A. Oral glucosamine sulphate in the management of arthrosis: report on a multi-centre open investigation in Portugal. Pharmatherpeutica 1982; 3(3):157-68.

3. Vaz, A.L. Double-blind clinical evaluation of the relative efficacy of ibuprofen and glucosamine sulphate in the management of osteoarthrosis of the knee in out-patients. Current Medical Research and Opinion 1982; 8(3):145-149.

4. Kimmatkar N, Thawani V, Hingorani L, Khiyani R. Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee--a randomized double blind placebo controlled trial. Phytomedicine. 2003 Jan;10(1):3-7.

5. Safayhi, H., Mack, T., Sabieraj, J., Anazodo, M.I., Subramanian, L.R., and Ammon, H.P.T. (1992) Boswellic acids: Novel, specific, nonredox inhibitors of 5-lipoxygenase. J. Pharmacol. Exp. Ther. 261(3), 1143-1146.

6. Boswellia serrata. Alternative Medicine Review Monographs – Volume One. 2002.

7. Kulkarni RR, Patki PS, Jog VP, Gandage SG, Patwardhan B. Treatment of osteoarthritis with a herbomineral formulation: a double-blind, placebo-controlled, cross-over study. J Ethnopharmacol. 1991 May-Jun;33(1-2):91-5.

8. Majeed, M., Badmaev, V., Shivakumar, U., Rajendran, R. Curcuminoids: Antioxidant Phytonutrients. 1995. PiScataway, NJ: NutriScience Publishers.

9. Snow, J.M. Herbal Monograph: Curcuma longa L. (Zingiberaceae). The Protocol Journal of Botanical Medicine, Autumn 1995:43-46.

10. Rao, S., Rao, M.N.A. Nitric oxide Scavenging by curcuminoids. J Pharm. Pharmacol. 1997;49:105-7.

11. Ramsewak, R.S., DeWitt, D.L., Nair, M.G. Cytotoxicity, antioxidant, and anti-inflammatory activities of Curcumins I-III from Curcuma longa. Phytomedicine 2000;7(4):303-308.

12. Deodhar, S.D., Sethi, R. Srimal. R.C. Preliminary study on antirheumatic activity of curcumin (diferoyl methane). Indian J Med Res 1980;71:632-34.

13. Atal, C., Zutshi, U., Rao, P. Scientific evidence on the role of Ayurvedic herbals on bioavailability of drugs. Journal of Ethnopharmacology 1981;4:229-232.

14. Bioperine®–Nature's Bioavailability Enhancing Thermonutrient. Executive Summary. 1996; Sabinsa Corporation, PiScataway, N.J.

15. Shoba, G., et al. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Medica 1998;64(4):353-6.

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Date: October 26, 2005 05:57 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Preventing Chronic Health Problems with AHCC

Preventing Chronic Health Problems with AHCC

In a country supposedly as healthy as ours, an estimated 175 million people suffer from one form of chronic imbalance or another. This can take the form of obesity, which is the second leading cause of preventable death in the United States, second only to cigarette smoking; challenges to heart health, blood pressure, blood glucose levels, joint and cell health ,to name just a few.

In fact ,treating chronic health problems is what modern medicine has become .Sure, there are still many acute illnesses treated by modern medicine; but for the most part, we are fortunate enough to have long life spans and the health issues that go along with it. Therefore it is important to make sure that out immune systems are up to the task. That is where AHCC should become part of our daily lives.

AHCC is an nutritional supplement that was developed and is manufactured solely in Japan under strict practices. It is a hybridized extract of medicinal mushrooms where the active ingredient is an oligosaccharide made from the mycelia of several species of mushrooms, grown in rice bran.

AHCC and Cell Senescence

Every few years, a new buzz word comes along in medical circles. The latest one to be used both in a positive and negative fashion is senescence. For example, if an unhealthy cell can be artificially made to senesce, or grow old, then it will die sooner. If senescence of healthy cells can be delayed, that is an amazing achievement.

AHCC is the first nutritional supplement that shows principles of being able to promote certain cells in the immune system that keep us young and healthy, thus delaying immunosenesnscence.

AHCC and the Immune System

In order to get a full appreciation of how important taking AHCC on a daily bases is, one needs to understand the intimate role the immune system plays in our daily lives. It is responsible for riding our bodies of the unhealthy cells that are produced every day. The immune system protects us from the polluted air we breathe, the chemicaalized foods we eat, and most importantly, from the stress we bring upon ourselves just by the very nature of the way we live our lives. Our bodies were made for flight or fight capability; but never in history have we been in that mode on a daily basis. Our immune systems are under constant assault and it is up to you to take care of it even though you may not even be aware that it is there. We tend to only to think of our immune system when it is not working-when suffer mild or severe health challenges.

Without getting into too much detail, our immune system is a complex series of cells that all communicate with each other and must be balanced correctly in order for us to stay healthy. AHCC is able to encourage the helpful cells such as the natural killer (NK) cells while suppressing the ones that foster problems.

I am in clinical practice on a daily basis and use AHCC in almost every one of my patients. It is very versatile because of its effects on the immune system.

A Company Committed to Excellence

If everything I just told you wasn’t enough to convince you that AHCC should become part of your daily armamentarium, then here’s more fuel. AHCC is produced by a chemical company that is committed to excellence in manufacturing and most importantly in research. They have supported research at hospitals around the world, including local ones such as Columbia University, Harvard University and the University of California.

In fact, I just returned from a trip to Sapporo, Japan where the product is made and where each year, a team of scientists and medical professionals gather to discuss the latest research on AHCC, GCP, and oliganol-all products made by the same company. This was the 13th annual symposium and was attended by close to 1000 professionals.

It is remarkable to me that this company is able to produce such well-documented research while still being a nutritional supplement company, which shows it can be done. To me, this is the sign of a nutritional supplement worth recommending. If it does what it says it is supposed to do and has research to support those claims, than that is something you want in your daily diet.

So, even though you may never have given your immune system a second thought, you really should; and the best way to help it out is by taking AHCC on a daily basis, just like I do. I recommend 500 mg per day in the summer months and 1500 per day in the winter months as a simple preventive. Stay healthy!

About the Author

Fred PeScator, M.D., a traditionally trained physician practicing nutritional medicine, is President of the AHCC Research Association. He is the author of The Hamptons’ Diet, Thin For Good and Feed Your Kids Well. Dr.PeScator lectures around the world, and has been featured on such shows as The View, The Today Show, Deborah Norville, The O’ Reilly Factor, and Extra. Recent interviews include Woman’s Health and Fitness, Let’s Live, the New York Times, the Wall Street Journal, Fortune and more. He is also the author of numerous papers and magazine articals. Dr.PeScator is actively involved in clinical research , and is instrumental in developing and clinically testing many of the leading nutritional products. He is the President-Elect of the International and American Association of Clinical Nutritionists and a member of the National Association of Physician Broadcasters.

The above article is for informational purposes only and is not intended to diagnose or treat a particular illness. The reader is encouraged to seek the advice of a holistically competent licensed professional health care provider. The information in this article has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

AHCC 49% OFF

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Date: October 13, 2005 04:45 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Benefits of Total Daily Formula

Benefits of Total Daily Formula

Mixed Carotenoids

All fruits and vegetables contain carotenes, the plant pigments responsible for the rich variety of colors we enjoy in the natural world. Beta carotene is the most familiar member of the carotene family. But beta carotene never exists by itself; it is always found with other carotenes in foods. We need more than just beta carotene alone. Carotenes are powerful antioxidants, which means they help reduce the body's free radical burden. Research suggests that carotenes work as a team to keep us healthy.5 Total Daily Formula provides beta carotene, alpha carotene, lutein, lycopene, zeaxanthin and cryptoxanthin from natural sources such as algal extracts, carrot oil, marigold and tomatoes (Caromix®).

Corn-Free Vitamin C

Total Daily Formula uses only corn-free vitamin C (ascorbic acid). The full daily intake of 6 tablets provides an exceptionally generous 800 mg of vitamin C.

Optimum B Vitamin Servings

Total Daily Formula supplies ample amounts of all essential B vitamins. Vitamin B3 is given as niacin plus an extra helping of niacinamide, the non-flush form of this important vitamin. The body uses pantothenic acid (vitamin B5) to deal with stress, so the formula provides 150 mg, which is 15 times the RDA. Vitamin B6 is another B vitamin people may run short of, so 60 mg -- 30 times the RDA -- is supplied. The formula contains 800 mcg of folic acid, the vitamin now recognized by the FDA as essential for prevention of neural tube defects in unborn babies. Folic acid also helps prevent accumulation in the body of homocysteine, a metabolite of the amino acid methionine.6 A high blood homocysteine level is now considered to be a risk factor for heart disease.7

Flavonoids

Flavonoids, also known as "bioflavonoids." are plant pigments widely distributed throughout the plant kingdom.8 Previously known as "Vitamin P," because they help reduce capillary permeability (leakiness) flavonoids are now regarded as "semi-essential" non-vitamin nutrients that benefit health in a variety of ways.9 In addition to maintaining the structure of blood vessels, flavonoids function as versatile antioxidants. Flavonoids protect vitamin C from destruction by free-radicals, helping to preserve the body's vitamin C supply.10 Total Daily Formula provides 100 mg of pure flavonoids from 112 mg of citrus extract.

Three superior sources of Calcium

Total Daily Formula contains three of the best absorbed and most effective forms of calcium available. MCHC (microcrystalline hydroxyapatite concentrate) is a naturally-derived compound composed of calcium, plus all the minerals and organic factors in living bone tissue. MCHC has been clinically shown to benefit bone health.11 Calcium citrate malate is a very well-absorbed form of supplemental calcium shown in recent research to be helpful for postmenopausal women.12,13 Calcium glycinate is chelated with the amino acid glycine, one of the most efficient mineral carriers for effective absorption.14,15

Magnesium glycinate

Magnesium is essential for strong bones and healthy hearts. This versatile mineral also regulates nerve function, keeps muscles relaxed and coordinates activity of over 300 enzymes in the body.16 Total Daily Formula contains 100 percent magnesium glycinate for exceptional absorption and gentleness on the intestinal tract.17 Magnesium glycinate has been clinically tested on people with severe malabsorption with excellent results.18

Trace Minerals

Total Daily Formula provides - in addition to zinc, chromium, selenium and iodine - vanadium and molybdenum. Vanadium helps maintain normal blood sugar.19 Molybdenum works as a co-factor for enzymes that help detoxify and eliminate foreign substances from the body.20

Bioperine® for Enhanced Absorption

Bioperine® is a natural extract derived from black pepper that enhances nutrient absorption. Preliminary trials on humans have shown significant increases in the absorption of nutrients consumed along with Bioperine®. 21 Betaine HCL - supplies HCL (hydrochloric acid) to assist digestion. All natural tablet coating made of vegetable concentrate and beta carotene.

Scientific References
1. Cheraskin, E. Ringsdorf, W.M., Clark, J.W. 1968. Diet and Disease. (p. 16). New Canaan, CT: Keats Publishing.

2. Morgan, K.J. et. al. Magnesium and calcium dietary intakes of the U.S. population. Journal of the American College of Nutrition. 1985;4:195-206.

3. Lakschmanan, F.L., Rao, R.B., Kim, W.W., Kelsay, J.L. Magnesium intakes, balances and blood levels of adults consuming self-selected diets. American Journal of Clinical Nutrition 1984;40:1380-89.

4. Mertz, W. The Essential Trace Elements. Fed. Proc. 1970;29:1482.

5. Perry, G. Byers, T. Dietary carotenes, vitamin C and vitamin E as protective antioxidants in human cancers. Annu. Rev. Nutr. 1992;12:139-59.

6. Landgren, F., et. al. Plasma homocysteine in acute myocardial infarction: Homocysteine-lowering effect of folic acid. J Int Med 1995;237:381-88.

7. Clarke, R., et. al. Hyperhomocysteinemia: an independent risk factor for vascular disease. New Eng J Med 1991;324:1149-55. 8. Havsteen, B. Flavonoids, a class of natural compounds of high pharmacological potency. Biochemical Pharmacology 32(7):1141-48.

9. Middleton, E. The flavonoids. TIPS 1984; 5:335-38.

10. Roger, C.R. The nutritional incidence of flavonoids: some physiological and metabolic considerations. Experientia 44(9):725-804.

11. Dixon, A. St. J. Non-hormonal treatment of osteoporosis. British Medical Journal 1983;286(6370):999-1000.

12. Smith, K.T. et. al. Calcium Absorption from a new calcium delivery system (CCM). Calcif Tissue Int 1987;41:351-352.

13. Dawson-Hughes, B. et. al. A controlled trial of the effect of calcium supplementation on bone density in postmenopausal women. New England Journal of Medicine 1990 Sep 27;323(13):878-883.

14. Albion Research Notes Vol. 4, No. 1, ©Albion Laboratories Jan,1995.

15. Ashmead, H.D. Intestinal Absorption of Metal Ions and Chelate, Springfield: Charles C Thomas, ©1985.

16. Wester, P.O., Dyckner, T. The importance of the magnesium ion. Magnesium deficiency-symptomatology and occurrence. Acta Med Scand 1992; (Suppl) 661:3-4.

17. Albion Research Notes Vol. 3, No. 1, ©Albion Laboratories, Feb 1994.

18. Schutte, S., et. al. Bioavailability of Mg diglycinate vs MgO in patients with ileal resections. Abstract 115, AJCN 1992;56(4).

19. Cohen, N. et. al. Oral vanadyl sulfate improves hepatic and peripheral insulin sensitivity in patients with non-insulin-dependent diabetes mellitus. J. Clin Invest 1995; 95:2501-09.

20. Sardesi, V.M. Molybdenum: An essential trace mineral element. Nutr Clin Pract 1993; 8:277-81.

21. Bioperine® - Nature's Bioavailability Enhancing Thermo-nutrient. Executive Summary' 1996; Sabinsa Corporation, PiScataway, N.J.

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Date: October 06, 2005 10:08 PM
Author: Darrell Miller (dm@vitanetonline.com)

Magnesium is a dietary mineral with a wide array of biological activities in the body. Magnesium participates in numerous life-essential processes that occur both inside and outside cells. Magnesium deficiency impacts normal physiologic function on many levels. Adequate magnesium is a fundamental requirement for optimum function of the cardiovascular system, the nervous system and skeletal muscle, as well as the uterus and GI tract. Magnesium deficiency can affect health of the heart, bones and blood vessels and alter blood sugar balance [1].

Magnesium–Important for Everyone, Deficient in Many The average person living in a modern country today very likely consumes less than the optimum amount of magnesium [2]. An abundance of data collected over the last two decades shows a consistent pattern of low magnesium intake in the U.S. This pattern cuts a wide swath across various age-sex groups. The USDA’s Nationwide Food Consumption Survey found that a majority of Americans consumed less than the recommended daily magnesium intake [3]. Twelve age-sex groups were studied and this low magnesium intake was true for all groups except 0 to 5 year olds.

An analysis of the nutrient content of the diets of 7,810 individuals age four and above included magnesium among several nutrients where the amounts supplied by the average diet "were not sufficient to meet recommended standards" [4]. The FDA’s Total Diet study examined the intakes of eleven minerals, including magnesium, among eight age-sex groups. Data was collected four times yearly from 1982 to 1984. Levels of magnesium, calcium, iron, zinc and copper were low for most age-sex groups [5]. Surveys conducted in Europe and in other parts of North America paint a similar picture. Loss of magnesium during food processing is one explanation for this global lack of adequate dietary magnesium [6].

In particular, the elderly may be susceptible to magnesium deficiency for a variety of reasons, including inadequate magnesium intake, poor absorption due to impaired gastrointestinal function and use of drugs such as diuretics that deplete magnesium from the body [7]. It has recently been theorized that magnesium deficiency may contribute to accelerated aging, through effects on the cardiovascular and nervous systems, as well as muscles and the kidneys [8].

Women who take both synthetic estrogen and calcium supplements may be at risk for low blood levels of magnesium [9]. Estrogen promotes the transfer of magnesium from blood to soft–tissues. Low blood magnesium may result if the ratio of calcium to magnesium intake exceeds 4 to 1. Magnesium supplementation is thus advisable for women taking estrogen and calcium.

Young adults are not immune to magnesium deficiency. The University of California’s Bogalusa Heart Study collected nutritional data from a cross-sectional sample of 504 young adults between age 19 and 28 [10]. The reported intake of magnesium, along with several other minerals and vitamins, was below the RDA.

Glycine is a highly effective mineral chelator. This is because it is a low-molecular-weight amino acid, hence is easily transported across the intestinal membrane. A study conducted at Weber State University found this particular magnesium glycinate was absorbed up to four times more effectively than typical magnesium supplements.

Magnesium-the Versatile Mineral

The average adult body contains anywhere from about 21 to 28 grams of magnesium. Approximately 60 percent of the body’s magnesium supply is stored in bone. Soft tissue, such as skeletal muscle, contains 38%, leaving only about 1 to 2% of the total body magnesium content in blood plasma and red blood cells. Magnesium in the body may be bound either to proteins or "anions" (negatively charged substances.) About 55% of the body’s magnesium content is in the "ionic" form, which means it carries an electrical charge. Magnesium ions are "cations," ions that carry a positive charge. In its charged state, magnesium functions as one of the mineral "electrolytes."

Magnesium works as a "co-factor" for over 300 enzymatic reactions in the body. Metabolism uses a phosphate containing molecule called "ATP" as its energy source. Magnesium is required for all reactions involving ATP [11]. ATP supplies the energy for physical activity, by releasing energy stored in "phosphate bonds".

Skeletal and heart muscle use up large amounts of ATP. The energy for muscle contraction is released when one of ATP’s phosphate bonds is broken, in a reaction that produces ADP. Phosphate is added back to ADP, re-forming ATP. ATP also powers the cellular "calcium pump" which allows muscle cells to relax. Because it participates in these ATP-controlled processes, magnesium is vitally important for muscle contraction and relaxation. By controlling the flow of sodium, potassium and calcium in and out of cells, magnesium regulates the function of nerves as well as muscles [12].

Magnesium’s importance for heart health is widely recognized. The heart is the only muscle in the body that generates its own electrical impulses. Through its influence on the heart’s electrical conduction system, magnesium is essential for maintenance of a smooth, regular heartbeat [13]. Magnesium appears to help the heart resist the effects of systemic stress. Magnesium deficiency aggravates cardiac damage due to acute systemic stress (such as caused by infection or trauma), while magnesium supplementation protects the heart against stress [14]. This has been found true even in the absence of an actual magnesium deficit in the body.

Evidence suggests that magnesium may help support mineral bone density in elderly women. In a two-year open, controlled trial, 22 out of a group of 31 postmenopausal women who took daily magnesium supplements showed gains in bone density. A control group of 23 women who declined taking the supplements had decreases in bone density [15]. The dietary intakes of magnesium, potassium, fruit and vegetables are associated with increased bone density in elderly women and men [16]. In an interesting animal study, rats were fed diets with either high or low levels of magnesium. Compared to the high magnesium-fed rats, bone strength and magnesium content of bone decreased in the low-magnesium rats, even though these rats showed no visible signs of magnesium deficiency [17]. While this finding may or may not apply to humans, it raises the possibility that diets supplying low magnesium intakes may contribute to weakening of bone in the elderly.

Maximizing Absorption––Chelated Minerals Explained Mineral absorption occurs mainly in the small intestine. Like any mineral, magnesium may be absorbed as an "ion," a mineral in its elemental state that carries an electric charge. Mineral ions cross the intestinal membrane either through "active transport" by a protein carrier imbedded in the cells lining the membrane inner wall, or by simple diffusion. The magnesium in mineral salts is absorbed in ionic form. However, absorption of ionic minerals can be compromised by any number of factors, including: 1) Low solubility of the starting salt, which inhibits release of the mineral ion, and 2) Binding of the released ion to naturally occurring dietary factors such as phytates, fats and other minerals that form indigestible mineral complexes [18].

A second absorption mechanism has been discovered for minerals. Experiments have shown that minerals chemically bonded to amino acids (building blocks of protein) are absorbed differently from mineral ions. This has given rise to the introduction of "chelated" minerals as dietary supplements. Mineral amino acid chelates consist of a single atom of elemental mineral that is surrounded by two or more amino acid molecules in a stable, ring-like structure.

Unlike mineral salts, which must be digested by stomach acid before the desired mineral portion can be released and absorbed, mineral chelates are not broken down in the stomach or intestines. Instead, chelates cross the intestinal wall intact, carrying the mineral tightly bound and hidden within the amino acid ring. The mineral is then released into the bloodstream for use by the body. Research by pioneers in the field of mineral chelation and human nutrition indicates that the best-absorbed chelates consist of one mineral atom chelated with two amino acids. This form of chelate is called a "di-peptide." Compared to other chelates, di-peptides have the ideal chemical attributes for optimum absorption [19]. Dipeptide chelates demonstrate superior absorption compared to mineral salts. For example, a magnesium di-peptide chelate was shown to be four times better absorbed than magnesium oxide [20].

Consumer Alert! Not all "amino acid chelates" are true chelates. In order for a mineral supplement to qualify as a genuine chelate, it must be carefully processed to ensure the mineral is chemically bonded to the amino acids in a stable molecule with the right characteristics. The magnesium bis-glycinate/lysinate in High Absorption Magnesium is a genuine di-peptide chelate ("bis" means "two"). It has a molecular weight of 324 daltons, considerably lower than the upper limit of 800 daltons stated in the definition of "mineral amino acid chelates" adopted by the National Nutritional Foods Association in 1996 [21].

Bioperine® For Enhanced Absorption Bioperine® is a natural extract derived from black pepper that increases nutrient absorption.* Preliminary trials on humans have shown significant increases in the absorption of nutrients consumed along with Bioperine® [22].

Scientific References 1. Abbott, L.R., R., Clinical manifestations of magnesium deficiency. Miner electrolyte Metab, 1993. 19: p. 314-22. 2. Durlach, J., Recommended dietary amounts of magnesium: Mg RDA. Magnesium Research, 1989. 2(3): p. 195-202. 3. Morgan, K.e.a., Magnesium and calcium dietary intakes of the U.S. population. Journal of the American College of Nutrition, 1985. 4: p. 195-206. 4. Windham, C., Wyse, B., Hurst, R. Hansen, R., Consistency of nutrient consumption patterns in the United States. J AM Diet Assoc, 1981. 78(6): p. 587-95. 5. Pennington, J., Mineral content of foods and total diets: the Selected Minerals in Food Survey, 1982 to 1984. J AM Diet Assoc, 1986. 86(7): p. 876-91. 6. Marier, J., Magnesium Content of the Food Supply in the Modern- Day World. Magnesium, 1986. 5: p. 1-8. 7. Costello, R., Moser-Veillon, P., A review of magnesium intake in the elderly. A cause for concern? Magnesium Research, 1992. 5(1): p. 61-67. 8. Durlach, J., et al., Magnesium status and aging: An update. Magnesium Research, 1997. 11(1): p. 25-42. 9. Seelig, M., Increased need for magnesium with the use of combined oestrogen and calcium for osteoporosis treatment. Magnesium Research, 1990. 3(3): p. 197-215. 10. Zive, M., et al., Marginal vitamin and mineral intakes of young adults: the Bogalusa Heart Study. J Adolesc, 1996. 19(1): p. 39-47. 11. McLean, R., Magnesium and its therapeutic uses: A review. American Journal of Medicine, 1994. 96: p. 63-76. 12. Graber, T., Role of magnesium in health and disease. Comprehensive Therapy, 1987. 13(1): p. 29-35. 13. Sueta, C., Patterson, J., Adams, K., Antiarrhythmic action of pharmacological administration of magnesium in heart failure: A critical review of new data. Magnesium Research, 1995. 8(4): p. 389- 401. 14. Classen, H.-G., Systemic stress, magnesium status and cardiovascular damage. Magnesium, 1986. 5: p. 105-110. 15. Stendig-Lindberg, G., Tepper, R., Leichter, I., Trabecular bone density in a two year controlled trial of peroral magnesium in osteoporosis. Magnesium Research, 1993. 6(2): p. 155-63. 16. Tucker, K., et al., Potassium, magnesium, and fruit and vegetable intakes are associated with greater bone mineral density in elderly men and women. Am J Clin Nutr, 1999. 69(4): p. 727-736. 17. Heroux, O., Peter, D., Tanner, A., Effect of a chronic suboptimal intake of magnesium on magnesium and calcium content of bone and bone strength of the rat. Can J. Physiol. Pharmacol., 1975. 53: p. 304-310. 18. Pineda, O., Ashmead, H.D., Effectiveness of treatment of irondeficiency anemia in infants and young children with ferrous bisglycinate chelate. Nutrition, 2001. 17: p. 381-84. 19. Adibi, A., Intestinal transport of dipetides in man: Relative importance of hydrolysis and intact absorption. J Clin Invest, 1971. 50: p. 2266-75. 20. Ashmead, H.D., Graff, D., Ashmead, H., Intestinal Absorption of Metal Ions and Chelates. 1985, Springfield, Illinois: Charles C. Thomas. 21. NNFA definition of mineral amino acid chlelates, in NNFA Today. 1996. p. 15. 22. Bioperine-Nature's Bioavailability Enhancing Thermonutrient. 1996, Sabinsa Corporation: PiScataway, N.J.

*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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Date: September 03, 2005 01:30 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Assists Digestion of Proteins, Carbohydrates and Fats

Assists Digestion of Proteins, Carbohydrates and Fats

Digestive enzymes are produced by the pancreas and secreted into the duodenum (upper small intestine), where proteins, carbohydrates and fats are broken down prior to absorption. As we age, the body’s capacity to produce enzymes may decline. Moreover, stress and other health difficulties can impact enzyme production. Overeating sometimes causes incomplete digestion. Heartburn, bloating, belching, discomfort, and a “sour stomach” often result.

Supplementation with the enzymes in Best For Digestion supports replenishment of the body’s enzyme level, helping to relieve the burden on an overworked pancreas. Digezyme® contains a neutral protease which, like the body’s intrinsic protein-digesting enzymes, is active in the neutral to alkaline pH range. In addition to amylase for starch digestion and lipase for fats, Digezyme® also supplies lactase, which acts on milk sugar, and cellulase, which breaks down cellulose.

Benefits of Enzyme Supplementation

Enzyme supplementation promotes improved digestion and delivery of vital nutrients to the system. This benefits good health in many ways, including better elimination, improved energy levels and maintenance of healthy body weight. Enzymes also help prevent accumulation of undigested foods in the large intestine, which can be a source of toxicity for the body.

Supports Digestive Function According to Ancient Principles of Traditional Chinese Medicine

Disturbed digestion, whether from overeating or generally poor digestive-organ function, results in sluggish movement of food through the alimentary canal and sub-optimal nutrient absorption. In traditional Chinese medical theory, the functions of transporting food and assimilating nutrients are governed by the stomach and “spleen.” The “Qi,” or vital functional energy of these organs, is complimentary in action. Stomach Qi “descends” as food travels downward through the digestive tract. Overeating and poor digestion interfere with the stomach’s normal descending function, resulting in “food stagnation.” If stomach Qi “rebels upward,” the result is nausea and vomiting. The herbs in Best For Digestion, which include stomach tonics such as Ginger root, assist the descending function of the stomach, and have been traditionally used as remedies for “food stagnation.”

The “spleen” in Chinese medicine encompasses the digestive role of the pancreas. Spleen Qi normally “ascends.” This can also be explained from a Western perspective. When nutrients are absorbed, they enter the circulation through intestinal capillaries, travel upward to the liver via the hepatic portal system, and continue up to the heart, eventually to be circulated throughout the body. Several of the herbs in Best For Digestion are traditional “spleen tonics” that support the ascending of spleen Qi, thus assisting optimum nutrient absorption.

Digestive Enzymes and Traditional Chinese Herbs: A Novel Approach to Better Digestion

Combining digestive enzymes and Chinese herbs that support digestive function is a unique new approach to better digestion. Whether the problem is temporary “food stagnation” or a more long-term need for improved digestive organ function, Best For Digestion provides valuable assistance.

Scientific References
1. Sabinsa Corporation, PiScataway, NJ. “Digezyme” ©1997

2. Chinese Herbal Materia Medica compiled and translated by Dan Bensky and Andrew Gamble©1986, Eastland Press, Inc., Seattle, WA.

3. Barillas, C., Solomons, N. Effective reduction of lactose maldigestion in preschool children by direct addition of ß-galactosidases to milk at mealtime. Pediatrics 1987;79(5):766-72.

4.DiPalma, J., Collins,M. Enzyme replacement for lactose malabsorpiton using a beta-d-galactosidase. J Clin Gastroenterol 1989;11(3):290-3.

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Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=760)

Date: August 19, 2005 12:47 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Curcumin - Turmeric Extract

Curcumin

Turmeric- History and Traditional Usage

Native to Southeast Asia, Curcuma longa is a tall
tropical shrub with large oblong leaves and pale yellow flowers.
The genus “Curcuma” belongs to the Zingiberaceae family, which
includes ginger.1 The plant possesses a large root structure
with fleshy, bulbous underground parts called “rhizomes.” These
rhizomes, known as turmeric root, are harvested at maturity,
dried and cured for commercial use. Chemical analysis shows that
dried turmeric contains essential and volatile oils, with a
curcuminoid content of 2.5 to 5.0 %.2

In addition to its
popularity as a spice, turmeric is used as a dye for cloth and
coloring agent in foods and cosmetics, thanks to its rich yellow
color. Turmeric also serves as a preservative, probably owing to
the antioxidant and antimicrobial properties of curcumin.
Extracts of Curcuma longa have demonstrated in vitro
antibacterial and anti-fungal effects.3

Turmeric is named in
ancient Ayurvedic and Chinese herbal texts as a traditional folk
remedy. Historically, turmeric was used externally for wounds,
and sprains, and internally for digestive complaints,
rheumatism, liver disorders, coughs and colds.4
Benefits

Protects cells and tissues by fighting free radicals.*

Supports joint function*

The numerous beneficial
effects attributed to turmeric stem in large measure from the
antioxidant properties of curcumin. Antioxidants neutralize free
radicals, which are highly unstable molecules that can damage
cellular structures through abnormal oxidative reactions.
Curcumin is a potent “Scavenger” of the superoxide radical, a
free radical that initiates potentially harmful oxidative
processes such as lipid peroxidation.5 Through this activity,
curcumin has been shown to protect skin cells from the injurious
effect of nitroblue tetrazolium, a toxin that generates
superoxide radicals. Curcumin also increases survival of cells
exposed in vitro to the enzyme hypoxanthine/xanthine oxidase,
which stimulates superoxide and hydrogen peroxide production.
Curcumin itself is not toxic to cells, even at high
concentrations. Pure curcumin was shown to be less protective
than a mixture of curcuminoids, indicating a possible synergism
among curcuminoids.6 Because free radicals are involved in aging
and exert harmful effects on skin, these results suggest
curcumin may help slow skin aging.

Curcumin demonstrates
several other in vitro effects linked to free radical
Scavenging. Curcumin Scavenges nitric oxide, a compound
associated with the body’s inflammatory response.7 Pure curcumin
and turmeric extracts protect red blood cells from lipid
peroxidation induced by hydrogen peroxide.8 Curcumin has been
shown to protect DNA from oxidative damage, inhibit binding of
toxic metabolites to DNA, and reduce DNA mutations in the Ames’
test.9 Although additional studies suggest an anticarcinogenic
effect of curcumin, through protection of DNA,10 one in vitro
study found that curcumin induced DNA damage in human gastric
mucosal cells.11 It is speculated that curcumin may act as a
pro-oxidant in the presence of transition metal ions such as
copper and iron. (This is true for other antioxidants, including
vitamin C.) Curcumin also demonstrates in vitro inhibition of
COX-I and COX-II enzymes, which are involved in the inflammatory
reaction.12 Together these results strongly suggest that
curcumin is a potent bioprotectant with a potentially wide range
of therapeutic applications.

Animal studies- In vivo protective effects

Through its free radical Scavenging
properties, curcumin has shown bioprotective effects in animals.
In one study, rats were treated with isoproterenol, a chemical
that causes cardiac hypertrophy (enlargement of the heart) due
to abnormal collagen metabolism. Co-treatment with curcumin
reversed the degradation of collagen and cardiac hypertrophy
induced by isoproterenol.13 Curcumin protects mice from
detrimental effects of radiation, by stabilizing the glyoxalase
system, a biological system that regulates cell division.14
Curcumin protects livers of rats from the damaging effects of
carbon tetrachloride (CCl4), a potent hepatoxin that injures the
liver via its free radical metabolite, CCl3.15,16 Curcumin
protected rats from alcohol-induced brain damage, in a study in
which oral administration of curcumin reversed lipid
peroxidation, reduced levels of free-radical metabolites and
increased levels of glutathione, a major physiologic
antioxidant.17 Curcuma longa extracts have shown
anti-inflammatory effects in rats.18

Human Trials

Curcumin exhibits free-radical Scavenging ability when
administered to humans. In an open trial (uncontrolled), 18
healthy individuals ranging in age from 27 to 67 years consumed
a Curcuma longa extract, at a dose supplying 20 mg curcuminoids,
for 45 days. Before and after blood tests showed a statistically
significant decrease in lipid peroxides.19 Preliminary trials
have tested the anti-inflammatory action of curcumin, with
results that verify the traditional use of turmeric as an
anti-rheumatic herb. In a short-term double-blind, cross-over,
comparative study, 18 people received curcumin (1200 mg daily)
or phenylbutazone for two week periods. Both curcumin and
phenylbutazone produced measurable improvements in joint
flexibility and walking time. The subjects reported results only
with phenylbutazone, which may be explained by the short
duration of the trial.20 In a small placebo-controlled trial
comparing curcumin to phenylbutazone, 45 patients with
post-operative inflammation received curcumin, phenylbutazone or
placebo. The anti-inflammatory effects of curcumin and
phenylbutazone were comparable and superior to placebo.21
Curcumin has not been found to produce an analgesic (pain
relieving) effect.

Bioperine-Nature’s Absorption Enhancer
Boosts Curcumin Absorption*

Traditional Ayurvedic herbal
formulas often include black pepper and long pepper as
synergistic herbs. The active ingredient in both black pepper
and long pepper is the alkaloid, piperine. Experiments carried
out to evaluate the scientific basis for the use of peppers have
shown that piperine significantly enhances bioavailability when
consumed with other substances.22 Several double-blind clinical
studies have confirmed that Bioperine® increases absorption of
nutrients.23

Curcumin is poorly absorbed in the intestinal
tract, limiting its therapeutic effectiveness. Oral doses are
largely excreted in feces, and only trace amounts appear in the
blood. Concomitant administration of 20 mg of piperine with 2
grams of curcumin increases the bioavailability of curcumin by
2000%.24

Scientific References

1. Majeed, M., Badmaev,
V., Shivakumar, U., Rajendran, R. Curcuminoids. 1995.
PiScataway, NJ: NutriScience Publishers.
2. Srimal, R.C.
Turmeric: a brief review of its medicinal properties.
Fitoterapia 1997;68(6):483-93.
3. Ammon, H.P.T., Wahl, M.A.
Pharmacology of Curcuma longa. Planta Medica 1991;57:1-7.
4.
Snow, J.M. Herbal Monograph: Curcuma longa L. (Zingiberaceae).
The Protocol Journal of Botanical Medicine, Autumn
1995:43-46.
5. Rao, N.S., Rao, M.N.A. Free radical Scavenging
activity of curcuminoids. Arzneim.-Forsch./Drug Res.
1996;46(2):169-171.
6. Bonté. F. et al. Protective effect of
curcuminoids on epidermal skin cells under free oxygen radical
stress. Planta Medica 1997;63:265-66.
7. Rao, S., Rao, M.N.A.
Nitric oxide Scavenging by curcuminoids. J Pharm. Pharmacol.
1997;49:105-7.
8. Lalitha, S., Selvam, R. Prevention of
H2Os-induced red blood cell lipid peroxidation by aqueous
extracted turmeric. Asia Pacific J Clin Nutr
1999;8(2):113-14.
9. Deshpande, S.S., Maru, G.B. Effects of
curcumin on the formation of benzo[a]pyrene derived DNA adducts
in vitro. Cancer Letters 1995;96:71-80.
10. Subramanian, M., et
al. Diminution of singlet oxygen-induced DNA damage by curcumin
and related antioxidants. Mutation Research
1994;311:249-55.
11. Blasiak, J., Trzeciak, A., Kowalik, J.
Curcumin damages DNA in human gastric mucosa cells and
lymphocytes. Journal of Environmental Pathology, Toxicology and
Oncology 1999;18(4):271-76.
12. Ramsewak, R.S., DeWitt, D.L.,
Nair, M.G. Cytotoxicity, antioxidant, and anti-inflammatory
activities of Curcumins I-III from Curcuma longa. Phytomedicine
2000;7(4):303-308.
13. Nirmala, C. Anand, S., Puvanakrishnan,
R. Curcumin treatment modulates collagen metabolism in
isoproterenol induced myocardial necrosis in rats. Molecular and
Cellular Biochemistry 1999;197:31-37.
14. Choudhary, D.,
Chandra, D. Kale, R.K. Modulation of radioresponse of glyoxalase
system by curcumin. Journal of Ethnopharmacology
1999;64:1-7.
15. Park, E-J. et al. Protective effect of
curcumin in rat liver injury induced by carbon tetrachloride. J
Pharm. Pharmacol. 2000;52:437-40.
16. Deshpande, U.R. et al.
Protective effect of turmeric (Curcuma longa L.) extract on
carbon tetrachloride-induced liver damage in rats. Indian
Journal of Experimental Biology 1998;36:573-77.
17.
Rajakrishnan, V. et al. Neuroprotective role of curcumin from
Curcuma longa on ethanol-induced brain damage. Phytotherapy
Research 1999;13:571-74.
18. Arora, R.B. Basu, N., Kapoor, V.,
Jain, A.P. Anti-inflammatory studies on Curcuma longa
(Turmeric). Indian J Med Res 1971;59(8):1289-95.
19.
Ramirez-BoSca, A. et al. Antioxidant curcuma extracts decrease
the blood peroxide levels of human subjects. Age
1995;18:167-69.
20. Deodhar, S.D., Sethi, R. Srimal. R.C.
Preliminary study on antirheumatic activity of curcumin
(diferoyl methane). Indian J Med Res 1980;71:632-34.
21.
Satoskar, R.R., Shah, S J. Shenoy, S.G. Evaluation of
anti-inflammatory property of curcumin (diferoyl methane) in
patients with postoperative inflammation. International Journal
of Clinical Pharmacology, Therapy and Toxicolgy
1986;24(12):651-54.
22. Atal, C., Zutshi, U., Rao, P.
Scientific evidence on the role of Ayurvedic herbals on
bioavailability of drugs. Journal of Ethnopharmacology
1981;4:229-232.
23. Bioperine®–Nature's Bioavailability
Enhancing Thermonutrient. Executive Summary. 1996; Sabinsa
Corporation, PiScataway, N.J.
24. Shoba, G., et al. Influence
of piperine on the pharmacokinetics of curcumin in animals and
human volunteers. Planta Medica 1998;64(4):353-6.

© 2002
Doctor's Best, Inc. Revised 8/13/02

*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

--
Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=734)

Date: June 21, 2005 05:31 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Fats and Oils: Clearing the Confusion

Fats and Oils: Clearing the Confusion

By Fred PeScatore, M.D.

Aside from tax forms, it's hard to find anything more confusing to consumers than fats and oils. Fat-free diehards still don't know that fat is essential for the brain, hormones, cellular membranes: life itself. The clueless still use shortening, margarine and damaged grocery store vegetable oils. But what worries me more is that supposedly educated consumers aren't even getting it right. Should we be surprised since their doctors probably don't know the truth?

Mistakes made by your customers. They:

* Likewise, oil is oil when it comes to calories. Even 10-W-40 has 9 calories per gram. Protein and sugar are about half that. What is important is the type of fat in the oil and monounsaturated is the best.

I hope this helps you educate consumers about the proper use of fats. Unfortunately, that still leaves a long list of other things they've been misled about.

--
Vitanet ®

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Fats for Life - the quality of the fat you eat is probably much more important than the...

Date: June 12, 2005 02:39 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Fats for Life - the quality of the fat you eat is probably much more important than the...

Fats for Life by Henry Wolfe Energy Times, August 6, 2003

For years, many experts argued that the only good fatty foods were the ones you didn't eat. That was a big, fat mistake. Overwhelming evidence now shows that certain fats are not only necessary for optimal health, but that the quality of the fat you eat is probably much more important than the quantity.

Threatening Trans Fats

"The biggest thing wrong with the fats Americans eat today is that they are eating too many trans fatty acids," says Fred PeScatore, MD, author of The Allergy and Asthma Cure (John Wiley). "About 42,000 foods contain trans fats. These fats are linked to a higher risk of heart disease, stroke and cancer."

Trans fatty acids are fats that form when food manufacturers add hydrogen to fat molecules, a process called hydrogenation that makes fats stay fresh longer without growing rancid. Trans fats also form when foods are fried.

Hydrogenation extends the shelf life of refined foods like cakes, donuts, and crackers. Unfortunately, it also creates fats that many experts believe can compromise your health. In a study of the health effects of trans fats, 26 people agreed to eat a diet that changed every five weeks, continually shifting the types of fats in their meals (American Heart Association's Scientific Sessions 2000). All of the diets in the study provided 30% of calories from fat. One fifth of the fat came from either soybean oil, semi-liquid margarine, tub margarine, shortening, stick margarine or butter.

"We were interested in assessing what would happen when we substituted one fat for another," notes researcher Alice H. Lichtenstein, DSc, professor of human nutrition at Tufts University, Boston.

The study showed that as people ate more trans fatty acids (in the more solid margarines) and fewer polyunsaturated fats (in the liquid oils), their triglycerides increased after each meal. Triglycerides are blood fats that boost heart disease risk.

For instance, when these folks ate stick margarine, which is high in trans fats, their triglycerides climbed an average 18% higher than when they ate semi-liquid squeeze bottle margarine, a type of margarine that is softer because it is less hydrogenated. Stick margarine raised heart disease risk by causing a drop in HDL, or "good" cholesterol. Although butter increased HDL, it also caused a significant increase in LDL, the "bad" cholesterol that raises heart disease risk.

Dietary Advice

"The best dietary advice we can give people is to minimize their intake of animal and hydrogenated fats in order to reach the American Heart Association's target of 10% or less of total calories from saturated fat and trans fatty acids," Dr. Lichtenstein says. "That would mean consumers choosing low-fat and non-fat dairy products and lean cuts of meat, and the food industry decreasing the amount of hydrogenated fats used in their products." According to a study at Johns Hopkins University (Amer Coll of Card, 52nd Scientific Session, 3/30/03, Chicago), people who eat saturated fat have more visceral fat, fat surrounding their internal organs. This fat around the waist is now seen as a risk factor for heart disease and other illnesses.

Another hidden problem in our fat consumption, according to Dr. PeScatore, hides within canola oil. Dr. PeScatore says that although many consumers believe canola oil is beneficial to health, the refined canola oil sold in the US has had its potential health benefits removed during processing.

"People still think canola oil is healthy and eat too much of it," he says. "The problem with canola is that it is highly processed and refined....Processors hydrogenate canola oil to keep it from getting rancid."

According to Fred Ottoboni, PhD, coauthor of The Modern Nutritional Diseases (Vincente Books), "Canola oil is lightly hydrogenated to take out the omega-3 fatty acids (the healthiest, but most unstable, fats) and then the food manufacturers filter the trans fats out. I don't worry about the trans fats in canola, but the problem is the huge ratio of omega-6 fatty acids to omega-3s."

To get more of the omega-3 fatty acids, which are lacking in most Americans' diets, Dr. PeScatore advocates using macadamia nut oil. "Macadamia nut oil is higher in monounsaturated fats than olive oil; it is the healthiest fat with an omega-3 to -6 ratio of one to one."

The Omega-3 Difference

Omega-3 and omega-6 fatty acids are basic forms of fat found in oils. Fish oil, hempseed and flax oil are high in what are called omega-3s. Certain plant-derived oils like corn and soy are richer in omega-6 fatty acids.

"Primitive humans ate a diet that contained a one-to-one ratio of omega-3s and omega-6s," says Dr. PeScatore. "Today we (Americans) eat 20 times more omega-6 than -3; that's why we suffer so much chronic disease and chronic inflammation. For instance, the Japanese eat a (much better) diet that contains a two-to-one ratio of omega-6 fatty acids to omega-3." "Not all omega-6s are bad," he adds, "we just eat too many of them."

Switching to healthier fat isn't hard. Eat more fish. When cooking, stick to oils like olive oil and macadamia oil. The quality of your oil and your health may improve in a big, fat way.

--
Vitanet ®

Solaray - Ultimate Nutrition - Actipet Pet supplements - Action Labs - Sunny Greens - Thompson nutritional - Natural Sport - Veg Life Vegan Line - Premier One - NaturalMax - Kal

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Date: May 12, 2005 09:33 AM
Author: Darrell Miller (dm@vitanetonline.com)

Keeping the Intestines Healthy

"Friendly Bacteria" Therapy Breakthrough

by Richard Conant, L.Ac., C.N.

Ninety percent of the cells found in the human body are not of human origin.

No, this does not mean we are all products of some sinister alien experiment.

The human body is made up of about 10 trillion cells. This huge number is dwarfed by the bacteria we all carry around in our intestinal tracts. The lower bowel is a campground for roughly 100 trillion bacteria, single-celled plant organisms that can be seen only through a microscope.

When we enjoy good intestinal health, the bulk of these bacteria are beneficial. Known as "friendly flora," these tiny guests help digest our food by breaking down undigested proteins, fats and carbohydrates. The friendliest of the friendly bacteria are the "lactobacilli," so named because they produce lactic acid in the bowel, by fermenting carbohydrates. This lactic acid production is profoundly important for keep the intestines healthy. And good intestinal health is the foundation of overall health.

How do we maintain a thriving population of lactic acid-producing bacteria in the gut? First introduced into the human body through mother's milk, lactobacilli are somewhat fragile. Stress, poor diets, and antibiotics can kill them off. They should be replanted fairly regularly throughout life. One way to do this is through consumption of cultured milk products such as sour milk, kefir and yogurt, which contain live lactobacilli. They can also be consumed in dietary supplements, but this may or may not be a reliable route. Bacterial products do not keep very well on the shelf, they require refrigeration, and are largely destroyed on the trip from the mouth to the gut by our own digestive juices.

Introducing Lactobacillus sporogenes- a revolutionary new friendly bacteria supplement.

This article will focus on one particular species of lactobacilli, a relatively unknown member of the family called Lactobacillus sporogenes. This lactic-acid producing bacteria may prove to be one of the most practical forms for use in supplements, thanks to a unique property not shared by the more well-known friendly flora such as acidophillus. L. Sporogenes is a spore-forming bacteria. Safely enclosed within a spore coat that protects it from the environment, L. sporogenes is resistant to heat, oxygen and digestive acids. Once L. sporogenes reaches the intestines, its spore coat dissolves, freeing the bacteria to multiply and churn out the beneficial lactic acid. (The spore coat, made up of a calcium-protein-carbohydrate complex, is harmless).1

The difficulty of keeping friendly bacteria supplements alive is an ongoing problem for manufacturers of these products. Studies have analyzed various commerical products claiming to contain acidophilus and found they often contain few live bacteria.2,3 L. Sporogenes is naturally microencapsulated; this insulates it from the gauntlet through which friendly bacteria in dietary supplements must pass.1 Autointoxication-Poisoning by Bacterial Toxins The intestinal tract may also play host to pathogenic, or disease-causing bacteria. These "unfriendly flora" cause putrefaction and release injurious toxins into the lower bowel. This healthy picture is all too common, and has long been concern of wholistic health practitioners.

The concept of "autointoxication," poisoning of the body by intestinal toxins, was popular among doctors in the late 19th and early 20th centuries. An editorial on the dangers of autointoxication which appeared in the June 3, 1893 issue of the Journal of the American Medical Association (JAMA) declared that "most likely a large majority of chronic diseases take their origin from this cause."4 The famous Russian physician Eli Metchnikoff pioneered the use of lactobacteria for preventing autointoxication and restoring bowel health. His landmark work 'Prolongation of Life' sparked interest in lactobacilli as a food supplement.5,6

Naturopathy, widely practiced during the early twentieth century, has always stressed the fundamental importance of bowel cleansing. With the advent of so-called "scientific medicine," naturopathy slipped into decline, and the concept of autointoxication was discredited. Over the last thirty years or so, this has changed. Naturopathic medicine has rebounded, and the importance of bowel health is once again recognized. A paper published in the New England Journal of Medicine in 1964, while opining that autointoxication "was exploited by quacks and faddists" in the early 1900's concedes that "the concept of autointoxication must now receive serious consideration."7

Leaders in the rebirth of natural medicine such as Dr. Bernard Jensen have helped educate the public about the importance of keeping the bowels healthy through regular use of lactobacilli. Jensen is well-known for his extensive studies of regions such as the Hunza Valley in Pakistan where people commonly live well over one hundred years. Jensen and others have noted that the consumption of fermented dairy products containing lactobacilli is a common dietary practice in these areas. Their observations have contributed to the popularity of friendly bacteria supplements. At the same time, clinical research has provided ample evidence of the beneficial effects of lactobacteria supplementation.5,9<.sup>

Eubiosis-Keeping a Healthy Bacteria Population in the Intestinal Tract

In his book 'Tissue Cleansing Through Bowel Management, which contains a wealth of valuable wisdom on intestinal health, Dr. Jensen writes, "Where health and vitality are found, we invariably find the friendly and beneficial microbes ... To a large extent the flora in the bowel determines the state of health in an individual."8 In a healthy bowel the friendly flora make up the bulk of the bacteria population. The unfriendly, disease-causing organisms are in the minority. The good bacteria keep them firmly under control. This healthy microbial balance in the gut is called "eubiosis."

Life in our modern industrial society is hardly favorable to eubiosis. Residents of the Hunza Valley lead unhurried lives in a pristine, pollution-free environment. They grow their own food in fertile, nutrient-rich soil, work close to the landÐand consume lactic-acid producing bacteria on a daily basis. For the rest of us who cannot hope to enjoy this enviable lifestyle, eubiosis is something we should never take for granted. This means taking proactive steps to plant the seeds of health in our intestinal garden, by using a viable friendly bacteria supplement.

Supplements which help to populate the intestinal tract with friendly bacteria are known as "probiotics." The term "probiotic" literally means "for life.' (In contrast, "antibiotic" means "against life.") Probiotics restore the natural state of "eubiosis" that is so very important for health and longevity.

L. Sporogenes-an ideal probiotic

Not every species of lactobacilli qualifies as an effective probiotic. As noted above, many do not survive processing, storage and passage through the digestive system very well. The following attributes make L. Sporogenes an ideal probiotic supplement:1,10,11

1) Naturally microencapsulatedÐstable at room temperature and can be stored unrefrigerated for long periods without loss of viable organisms.

2) Tolerates heat, stomach acid and bile, allowing it to successfully travel into the lower bowel.

3) Non-pathogenic, has only beneficial effects on its host. Has similar characteristics as acidophilus: prefers a mild acid environment; produces lactic acid, digestive enzymes, etc.

4) Readily multiplies in the human gut. In the stomach, the spore coat absorbs moisture and begins to swell. Upon reaching the small intestine, the bacteria cells germinate and begin to multiply, doubling in number every 30 minutes.

5) Produces enzymes which help digest protein, fats and carbohydrates. These enzymes include lactose, the enzyme that digests milk sugar.12

6) Creates a favorable environment (mildly acidic) in the gut for other friendly bacteria to thrive. Prevents overgrowth of pathogenic organisms.

7) Produces lactic acid in the form of L- lactic acid only.

The last point is especially important. Lactic acid occurs in the form of three isomers (substances with identical molecular structures that have different shapes): L-lactic acid, D-lactic acid and DL-lactic acid. The D form is metabolized slowly, and can produce acidosis in the system. (Infants have a particularly difficult time metabolizing D-lactic acid.)11,13 DL-Lactic acid, the kind acidophilus makes, may be converted to either D or L.

The L form is the one we want. L. sporogenes is a "homofermenter," it makes L-lactic acid exclusively. Lactic acid keeps the gut mildly acidic. This acidity is essential for the gut to be a hospitable home for friendly bacteria, and stops the growth of the unwelcome disease-causing bacteria.

L. sporogenes has only one drawback. It is a transient visitor that does not permanently colonize in the digestive tract. A study on the retention of L. sporogenes found no bacteria in the feces six days after consumption was discontinued.14

L. Sporogenes-Results from Clinical Studies

L. Sporogenes is used extensively in Japan and approved by the Japanese equivalent of the FDA. L. sporogenes has been given to hospital patients suffering from intestinal complaints such as gas and bloating due to abnormal fermentation, constipation, diarrhea and indigestion. (These problems often occur after surgery or chemotherapy.) A total of 16 clinical reports are on record in Japanese hospitals, documenting 293 case of digestive complaints treated with L. sporogenes.15 The overall improvement rate is an impressive 86 percent. Results are typically seen within four to five days. L. sporogenes has also been used with success to clear up diarrhea in newborns.16 Like other lactobacilli, L. sporogenes lowers blood cholesterol. (Lactobacilli break down cholesterol and bile salts in the intestinal tract.) Researchers at a hospital in New Delhi, India gave L. sporogenes tablets to 20 patients with high cholesterol for twelve weeks.17 Total cholesterol levels were substantially reduced, along with LDL cholesterol, and the beneficial HDL rose slightly.

The popularity of L. sporogenes in other countries as an ideal friendly bacteria supplement will no doubt be soon matched in the U.S. This microscopic helper for intestinal health is now sold in probiotic products under the name "Lactospore®."

References

1. Gandhi, A.B., Nagarathnam, T. Probiotics in veterinary use. Poultry Guide 1990;27(3):43-47.

2. Brennan, M., Wanismail, B., Ray, B. Prevalence of viable Lactobacillus acidophilus in dried commercial products. Journal of Food Protection 1983;46(10):887-92.

3. Gilliland, S.E., Speck, M.L. Enumeration and identity of lactobacilli in dietary products. Journal of Food Protection 1977;40(11):760-62.

4. Dalton, R.H. The limit of human Life, and how to live long. JAMA 1893;20:599-600.

5. Shahani, K.M., Ayebo, A.D. Role of dietary lactobacilli in gastrointestinal microecology. American Journal of Clinical Nutrition 1980;33:2448-57.

6. Metchnikoff, E.. Prolongation of Life. New York: G.P. Putnam Sons;1908.

7. Donaldson, R.M. Normal Bacterial populations of the intestine and their relation to intestinal function. New Eng. J. Med. 1964;270(18):938-45.

8. Jensen, B. Tissue Cleansing Through Bowel Management. Escondido, CA: publ. by Bernard Jensen, D.C.;1980.

9. Schauss, A.G. Lactobacillus acidophilus: method of action, clinical application, and toxicity data. Journal of Advancement in Medicine 1990;3(3):163-78.

10. 'General InformationÐLactospore®' 1996; Sabinsa Corporation: PiScataway, NJ.

11. Gandhi, A.B. Lactobacillus sporogenes, An Advancement in Lactobacillus Therapy. The Eastern Pharmacist August 1998:41-44.

12. Kim, Y.M., Lee, J.C., Choi, Y.J., Yang, H.C. Studies on the production of beta galactosidase by lactobacillus sporogenes. Properties and application of beta galactosidase. Korean J. Appl. Microbiol. Bioeng. 1985;13(4):355-60.

13. Oh, MS. D-Lactic acidosis in a man with short bowel syndrome. New Eng J Med 1979;31(5):249-52.

14. Hashimo, K. et. al. New Drugs and Clinics 1964;13(9):53-66.

15. 'Abstracts of papers on the clinical studies of Lacbon' Unpublished data.

16. Dhongade, R.K., Anjaneyule, R. Lactobacillus sporogenes (Sporlac) in neonatal diarrhea. Unpublished data.

17. Mohan, J.C., Arora, R., Khaliullah, M. Preliminary observations on effect of Lactobacillus sporogenes on serum lipid levels in hypercholesterolemic patients. Indian J. Med. Res. 1990;92(B):431-32.

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Date: May 09, 2005 06:10 PM
Author: Darrell Miller (dm@vitanetonline.com)

It's in the Blood

The National Cholesterol Education Program (NCEP) last July lowered the threshold for considering the use of statin drugs—a move which some say was motivated more by profits than scientific evidence. For example, the Center for Science in the Public Interest pointed out that eight of the nine authors behind the new recommendations had financial ties to statin manufacturers, which stand to reap billions of dollars more from a category that grossed $14 billion in the U.S. last year. And though the Food and Drug Administration (FDA) in January decided against authorizing over-the-counter (OTC) sales of statin drugs, drug companies would still like to see this happen.

“The medical establishment’s pushing of these drugs to becoming the number one category of prescribed drugs in the world has led them to keep lowering the total cholesterol number that triggers the drug recommendation,” said Neil E. Levin, C.C.N., D.A.N.L.A., nutrition educator, product formulator, and “Truth Advocate” for NOW Foods (Bloomingdale, IL), which produces a number of supplements for addressing cholesterol. “This is despite the lack of evidence that total cholesterol means much as regards cardiovascular risks.

“Other tests are much more important in terms of predicting risks, including CRP (C-reactive protein), the balance of different cholesterol fractions, and homocysteine,” he continued. “Add adult-onset diabetes to the risk factors for cardiovascular disease (CVD).”

At the same time, the allegation that enormous sales potential lay behind the lower threshold for prescribing statin drugs illustrates how widespread the problem of hypercholesterolemia (elevated total cholesterol) is. More than 100 million Americans have elevated cholesterol (total cholesterol values of 200 mg/dl and higher), and of these, more than a third have high cholesterol (levels of 240 mg/dl and higher), according to the American Heart Association. Those numbers have unfavorable implications for the incidence of CVD, as high cholesterol is considered a risk factor for coronary heart disease and stroke.

While statin drugs haven’t garnered the same degree of negative publicity that COX-2 inhibitors have suffered lately, safety concerns have arisen nonetheless. For one thing, these drugs lower the liver’s production of coenzyme Q10 (coQ10) along with its production of cholesterol. “CoQ10 is related to energy production and immune functions, is an antioxidant, and [is] an important cardiovascular nutrient,” Levin said. “It is not good to lower one’s coQ10 levels by half!”

Moreover, said Levin, statins increase the tendency of muscle tissues to break down. “Combined with inactivity or certain drugs, this can stimulate muscle wasting,” he said. “Muscle is where a good deal of calories are burned, so a loss of muscle could affect mobility and energy production, potentially adding to obesity problems. These muscle changes occurred in patients and persisted for years after treatment was discontinued, as shown by muscle biopsies, even if no obvious muscle problems were observed by the patients.”

And the last word on the subject may not have been spoken. Predicted Dr. Frank King, Jr. president of King Bio Natural Medicine (Asheville, NC), “Once the appropriate studies are finished, these drugs, along with hypertensives, will hit the fan bigger than the COX-2 inhibitors.”

Also looking toward the future, Levin said that of the 20 million Americans who will be “targeted” for statin drug prescriptions under the new NCEP guidelines, “Some of these will want to try natural methods first. Others will rebel at the side effects of the drugs and experiment with alternative products.”

King and Levin both saw opportunity for natural products in the fallout from drug safety concerns, with King projecting that sales of his company’s cholesterol-related homeopathic remedies will double in 2005. “The reports of deaths from drugs will always overshadow the trumped-up studies and news reports blasting dietary supplements,” said Levin. “Vioxx knocked vitamin E off the media’s radar screens pretty rapidly, though we still see ignorant reporters citing that [Johns Hopkins] vitamin E analysis as if it were true. But the comparable safety of supplements means that open-minded people will want to at least try natural therapies before signing in to a lifetime of drug therapies. Meanwhile, the studies on natural products will continue to build our credibility.”

Those studies keep coming in, with at least four major findings published in the past few months, plus a heart-health claim on walnuts authorized by FDA. They join a raft of earlier findings that link natural products—branded and otherwise—to healthy cholesterol levels.

"Blur of Products"

With so many natural alternatives to cholesterol drugs available, it can be hard to keep track. “As with any other category, the blur of products as they caScade over several shelves means that the retailer needs to have a good sense of what works and what they want to recommend to their customers,” Levin said. “Really, each person needs a protocol that would include antioxidants, fiber, vitamins, herbs, and oils. The pre-mixed cholesterol support formulas are a good starting place.”

To help retailers get a sense of “what works,” here is an alphabetical discussion of several nutrients that have demonstrated benefits in serum cholesterol levels. They include the following:

Barley may help lower cholesterol, according to a report in the American Journal of Clinical Nutrition (2004, vol.80, no.5: 1185-1193). Twenty-five adults with mild hypercholesterolemia consumed a controlled diet low in total fat, saturated fat, and cholesterol for 19 weeks. They then added whole-grain products containing barley to their diets that contained low (0 g), medium (3 g), or high (6 g) amount of beta-glucan per day for five weeks. Total cholesterol was reduced by 4 percent 9 percent, and 10 percent, respectively. The diet with the highest amount of beta-glucan led to a decrease in LDL cholesterol of 17 percent.

Chromium. There’s evidence, Levin said, that chromium in doses of 500 mg a day may decrease levels of low-density lipoprotein (LDL, the so-called “bad” cholesterol) and total cholesterol while raising levels of high-density lipoprotein (HDL, or “good” cholesterol). At the annual meeting of the American College of Nutrition last October, a poster presentation on the safety of Benicia, CA-based InterHealth Nutraceuticals’ ChromeMate niacin-bound chromium won first prize; among other things, the presentation cited chromium’s role in maintaining healthy blood lipid levels.

Fatty Acids. The latest in a long line of studies demonstrating the benefits of fatty acids in heart health is a study published in The International Journal of Clinical Pharmacology and Therapeutics in December 2004. It showed that docosahexaenoic acid (DHA), an omega-3 fatty acid, can restore normal blood vessel function in children with inherited high cholesterol. The study, which used Martek DHA produced from microalgae, concluded that restoration of normal blood vessel function has the “potential for preventing the progression of early coronary heart disease in high-risk children.”

“The evidence continues to accumulate on the cardiovascular benefits of DHA for people of all ages,” said Henry “Pete” Linsert, Jr., chairman and CEO of Martek Biosciences, an ingredient supplier based in Columbia, MD. “This study clearly indicates that DHA played an important role in healthy blood vessel function in the children in this study.”

On the Omega-Research.com Website maintained by fish oil manufacturer Nordic Naturals (Watsonville, CA) can be found summaries of several earlier studies linking omega-3 fatty acids to maintaining healthy blood lipid levels, as well as related benefits such as elasticity of the arteries. In a 2003 study published in the American Journal of Clinical Nutrition, it was found that women receiving a mixture of 4 g eicosapentaenoic acid (EPA) and DHA along with 2 g of gamma-linolenic acid (GLA) had lower levels of LDL cholesterol after 28 days compared to those who received either the EPA/DHA supplements without DHA, EPA/DHA with a smaller dose of GLA, or GLA alone.

Flax is another source of omega-3s, and Arkopharma/Health From The Sun (Bedford, MA) offers FiProFLAX in a variety of forms. Marketing director Hugues P. Mas said the flax is “QAI [Quality Assurance International] certified organic and guaranteed GMO [genetically modified organism]-free.” On its Website, the company offers a cholesterol quiz geared to consumers, discussing the importance of omega-3s as well as other nutrients.

Garlic. Adding to an already considerable body of research demonstrating that garlic can lower total cholesterol, LDL cholesterol, and triglycerides while increasing HDL cholesterol, researchers at UCLA in 2003 reported that Kyolic aged garlic extract reduced or inhibited plaque formation in the arteries of 19 cardiac patients taking statin drugs.

Lead researcher Matthew Budoff, Ph.D. commented at the time that the study “suggests that aged garlic extract may be a useful and beneficial dietary addition for the people who have high cardiovascular risk or who have undergone heart surgery.” Budoff has since presented several trade show seminars sponsored by Los Angeles-based Wakunaga of America, the makers of Kyolic.

Guggul. In use for centuries as a component of Ayurvedic medicine, guggul—a gummy resin tapped from the Commiphora mukul tree, which is native to India—has been studied since the early 1960s for its hypolidemic (blood-lipid lowering) properties. Sabinsa Corp. (PiScataway, NJ), an ingredient supplier which produces a standardized extract under the brand name Gugulipid, says the studies on guggul indicate that its hypolipidemic activity can be attributed to more than one mechanism of action.

Among the possible mechanisms are: inhibition of cholesterol biosynthesis, enhancing the rate of excretion of cholesterol, promoting rapid degradation of cholesterol, thyroid stimulation, alteration of biogenic amines, and “high affinity binding and anion exchange.”

Homeopathy. “Homeopathy activates the body’s own control system to work properly,” said King. “This is the safest and most curative approach to take.

“Forcing the body into biochemical change even naturally doesn’t actually have the curative action of homeopathy,” King continued. “Homeopathy can even correct the genetic predispositions to disease we may have inherited from as deep as a thousand years into our family chain.” King Bio makes Artery/Cholesterol/BP, a homeopathic formula intended to help tone heart muscles and blood vessels.

Low glycemic index foods. In a study published in the February issue of the American Journal of Clinical Nutrition, researchers found that high glycemic load is negatively correlated to serum levels of HDL cholesterol. Assessing the relationship between blood levels of lipids and diet in a test population of 32 healthy males and females ages 11 to 25, the researchers found that glycemic load accounted for 21.1 percent of the variation in HDL cholesterol. They concluded that glycemic load appears to be an important independent predictor of HDL cholesterol in youth and noted that dietary restrictions without attention to glycemic load could unfavorably influence blood lipids.

Medicinal Mushrooms. Although its product SX-Fraction is intended primarily to address high blood sugar, Maitake Products, Inc. (MPI, Ridgefield Park, NJ) found in a clinical study that LDL cholesterol in diabetic patients declined modestly (from 142 mg/dl to 133 mg/dl) over a two-month period. Those taking SX-Fraction also lost about 7 lbs. in the same time period.

“The more impressive lowering of cholesterol, however, comes from the dietary fiber that is found in all medicinal mushrooms,” said Ellen Shnidman, manager of scientific affairs at MPI. She cited animal studies which documented the cholesterol-lowering properties of four different mushrooms: maitake, shiitake, agaricus, and enokitake.

For example, a study reported in the September 1996 issue of Alternative Therapies showed “a 44 percent reduction in total cholesterol in rats consuming maitake mushroom in their diet,” said Shnidman. “This cholesterol reduction is accompanied by weight loss, relative to rats eating a similar high-choelsterol diet without mushrooms. Apparently, cholesterol is excreted by the rats in sufficient quantity to aid in weight loss.”

Oat bran. A 2004 consumer study conducted by the Natural Marketing Institute (NMI, Harleysville, PA) for Nurture, Inc. (Devon, PA), which produces the ingredient OatVantage, found that 63 percent of consumers managing their cholesterol levels prefer oat-based ingredients.

Oat bran is the subject of a health claim authorized by FDA in 1999, and NMI research found that 69 percent of respondents preferred the FDA-permitted health claim, “Helps Lower Cholesterol,” over the model structure-function claim, “Helps Maintain Healthy Cholesterol Levels.” “This is significant for food, beverage, and dietary supplement manufacturers who want to increase sales by using a more consumer-desired claim on the product label,” said Griff Parker, Nurture CEO.

Plant sterols. Also the subject of an FDA-approved claim for heart health, plant sterols (structurally similar to cholesterol in humans) can block the absorption of cholesterol, according to a number of studies. In an “Ask the Doctor” publication (available online at www.atdonline.org), Decker Weiss, N.M.D. noted that sterols enter the same receptor sites that cholesterol enters on its way to the bloodstream. “The cholesterol, being blocked from absorption, remains in our intestines where it is eventually excreted,” Weiss wrote. General Mills has just introduced Yoplait Healthy Heart, a yogurt high in plant sterols.

Policosanol. A mixture of fatty alcohols derived from sugar cane or beeswax, policosanol has been favorably compared in clinical studies to several types of prescription drugs for managing cholesterol. On its own, policosanol was found in a 1999 study to reduce LDL cholesterol while raising levels of HDL cholesterol.

Probiotics. “Several studies have indicated that consumption of certain cultured dairy products resulted in reduction of serum cholesterol, as well as triglycerides,” wrote Dr. S.K. Dash, president of probiotic manufacturer UAS Laboratories (Eden Prairie, MN), in his Consumer Guide to Probiotics. Among other studies, Dash cited two controlled clinical studies from the VA Medical Center at the University of Kentucky.

“In the first study, fermented milk containing [Lactobacillus] acidophilus was accompanied by a 2.4 percent reduction of serum cholesterol concentration,” he wrote. “In the second study, a different L. acidophilus strain reduced serum cholesterol concentration by 3.2 percent. Since every 1 percent reduction in serum cholesterol concentration is associated with an estimated 2 to 3 percent reduction in risk for coronary heart disease [CHD], regular intake of fermented milk containing an appropriate strain of L. acidophilus has the potential of reducing risk for [CHD] by 6 to 10 percent.”

Dash said his company’s DDS Probiotics contain DDS-1 L. acidophilus, “which has been researched and demonstrated to show cholesterol-lowering effect.”

Psyllium. “Internal cleansing is very important” in maintaining healthy cholesterol levels, “especially if you do it with a lot of fiber,” said Sunil Kohli, vice president of Chino, CA-based Health Plus, Inc. The cholesterol-managing ability of fiber in general and psyllium in particular is “very well-established,” he said.

However, Kohli said, “It will probably do you no good if it’s random. It should be done on a regular basis, and it should be supervised. Consulting the doctor or pharmacist is important.”

Soy. The protein in soy “has evidence of lowering total cholesterol and LDL cholesterol, based on reviews of studies using over 20 g of soy protein per day,” said Levin. “Soy isoflavones are considered only partly responsible for this effect.”

Sytrinol. A patented proprietary formula derived from natural citrus and palm fruit extracts and containing citrus polymethoxylated flavones and palm tocotrienols, Sytrinol has been shown in clinical trials to improve total cholesterol, LDL cholesterol, and triglycerides by up to 30 percent, 27 percent, and 33 percent, respectively. Having just wrapped up Phase III of a long-term trial of Sytrinol, Chicago-based SourceOne Global Partners, which owns the exclusive worldwide license for intellectual property associated with the ingredient, is commencing a study that combines Sytrinol with plant sterols.

Tocotrienols. On its Website discussing the science and benefits of tocotrienols (www.tocotrienol.org), ingredient supplier Carotech Inc. (Edison, NJ) identifies several benefits for blood lipid levels. Tocotrienols, according to the Website, have been shown to “inhibit cholesterol production in the liver, thereby lowering total blood cholesterol;” “[suppress] hepatic HMG-CoA reductase activity [and result in] the lowering of LDL cholesterol levels;” and “inhibit cholesterogenesis by suppressing HMG-CoA reductase.”

New Weapons

There are also nutrients that are emerging as potential weapons in the fight against cholesterol. Levin cited rice bran oil, resveratrol, pantethine, l-carnitine, and niacin as showing promise.

With all of this, Levin said, it’s important for retailers to remember that “they are not allowed to discuss diseases and remedies unless there is an approved FDA health claim allowed on the label, as with soy protein and plant sterols. What is allowed are structure-function claims such as ‘cholesterol support,’ ‘promoting normal, healthy circulation,’ ‘homocysteine regulators,’ etc.”

Supplementation is only one tool for managing cholesterol levels, manufacturers pointed out. “Besides nutrition, lifestyle is a key to controlling cholesterol,” Levin said. “Eating a variety of antioxidant-rich foods will prevent the liver from churning out cholesterol as a ‘cheap’ antioxidant. The body uses oxidized cholesterol to patch leaky and damaged blood vessels, so the ability to build healthy collagen is a must, using nutrients like vitamin C, Pycnogenol, rutin, hyaluronic acid, and MSM.

“Don’t forget exercise and stress reduction,” he added. “Stress results in high cortisol levels—usually accompanied by poor blood lipid levels—and a lack of good sleep to produce unhealthy people.” VR

Vitamin Retailer Magazine, Inc., 431 Cranbury Road, East Brunswick, NJ 08816 //www.oprmagazine.com/

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