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The Importance of Collagen for Your Health: Why You Should Care   
Date:
November 06, 2023 04:50 PM
The Importance of Collagen for Your Health: Why You Should Care
Have you ever heard about collagen? It might have been a buzzword in the beauty industry, but it's important to know that collagen is much more than just skin-deep. Collagen is actually a protein that plays a crucial role in providing structure, strength, and support to different parts of our bodies such as skin, bones, tendons, and ligaments. Lets explore the importance of collagen for your health, its different types and functions, the effects of collagen loss on the body, factors that affect collagen production, and how to boost collagen levels naturally.
Collagen production declines naturally with aging, leading to visible signs of aging like wrinkles, sagging skin, and brittle nails. However, several lifestyle factors also contribute to collagen loss like smoking, consuming sugary foods, and excessive sun exposure. Medical conditions like scleroderma and Ehlers-Danlos syndrome also lead to reduced collagen production.
Collagen loss can have various detrimental effects on the body. One of the most visible effects is on the skin where collagen loss leads to wrinkles, fine lines, sagging, and dryness. Collagen loss also affects joints, resulting in pain and stiffness. Since collagen is crucial to maintaining bone structure, a decrease in collagen levels weakens the bones and muscles, causing osteoporosis. Collagen is important for the digestive tract lining, so when the body lacks sufficient collagen, people could experience digestive issues. Lifestyle Habits Leading to Collagen Loss: Several lifestyle habits exacerbate the natural decline in collagen production, thereby speeding up the aging process and negatively affecting overall health. First among these is smoking. The chemicals present in cigarettes damage collagen and elastin, causing premature skin aging with characteristic wrinkles and sagging. Not only does smoking impact the skin, but it also affects collagen-rich organs and tissues, leading to various health problems. Next is the consumption of excessive sugar and refined carbohydrates. A high-sugar diet interferes with collagen's ability to repair itself, leading to inflammation and collagen cross-linking that results in skin aging and joint discomfort. Refined carbohydrates spike blood sugar levels, encouraging the same damaging process. Last but not least, ultraviolet (UV) light exposure, particularly from the sun, can also lead to significant collagen loss. UV light increases collagen breakdown by activating enzymes called matrix metalloproteinases that degrade collagen and elastin. This exposure results in photoaging of the skin, characterized by deep wrinkles, leathery texture, and pigmentation changes. Therefore, it's crucial to protect your skin from the sun by wearing SPF every day, even on cloudy days.
Fortunately, several natural ways can help boost collagen levels in your body. Maintaining a balanced diet rich in vitamins and minerals such as vitamin C, zinc, copper, and iron is key to boosting collagen levels. Vitamin C is vital in the production of collagen, which makes it an essential nutrient for the body. Excessive sun exposure and smoking lead to the accumulation of free radicals that damage collagen, so avoiding these is key. In addition, the topical use of skincare products like sunscreen and moisturizers protects and nourishes collagen and helps maintain healthy skin. Exercise such as weight training and yoga can help stimulate collagen synthesis, ensuring youthful-looking skin, healthy joints, and strong bones. Common types of collagen!
Collagen is an essential protein that is vital for overall health and well-being. It provides support and structure to different body parts, ensuring their optimum functionality. The decline in collagen production is an inevitable part of aging, but several natural ways can help boost its levels. Maintaining a balanced diet, avoiding habits that damage collagen, and practicing regular exercise can help maintain healthy collagen levels. It's crucial to remember that relying solely on supplements may not necessarily boost collagen levels, so it's best to consult your healthcare provider before taking them. So, go ahead and adopt healthy habits to maintain healthy levels of this crucial protein. Your body will thank you for it!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6588) The Many Health Benefits of Copper Glycinate 
Date:
October 25, 2022 04:49 PM
You may not realize it, but copper is essential for many different bodily functions. This trace mineral is involved in energy production, iron metabolism, connective tissue syntheses, and neurotransmitter production. Copper is also critical for bone health, cardiovascular health, lipid metabolism, neurological health, skin health, and free radical protection. Keep reading to learn more about the many health benefits of copper. Copper and Energy Production One of the most important roles that copper plays in the body is in energy production. Copper is a key component of mitochondria, which are known as the "powerhouses of the cell." The mitochondria produce ATP (adenosine triphosphate), which is the energy currency of the cell. Therefore, without adequate copper levels, your cells would not be able to produce enough ATP for optimal function. Copper and Iron Metabolism Another important role of copper is in iron metabolism. Copper is necessary for the absorption and utilization of iron in the body. Iron is a key component of hemoglobin, which carries oxygen around in the blood. Therefore, without adequate copper levels, your body would not be able to properly utilize iron, leading to anemia or other problems. Copper and Connective Tissue Synthesis Copper is also necessary for the synthesis of collagen and elastin, two proteins that make up connective tissue. Connective tissue includes things like skin, tendons, ligaments, and cartilage. Therefore, copper is necessary for healthy skin as well as strong tendons and ligaments. As you can see, copper plays many vital roles in the body. If you are deficient in copper, you may experience fatigue, anemia, weak bones or connective tissue, problems with lipid metabolism or neurological function, or poor skin health. To ensure that you are getting enough copper in your diet, eat foods like liver, oysters, lobster, dark chocolate, avocados, almonds, mushrooms ,or leafy green vegetables. You can also take a copper supplement if needed.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6526) Collagen for Healthy Joints, Bones and Skin
Date:
October 03, 2022 03:04 PM
Collagen is a protein that is found in abundance in mammals. It makes up about 30% of the body's protein and is known for its roles in bone, joint and skin health. Studies have shown that hydrolyzed collagen can help to support strong bones, healthy joints and smooth, hydrated skin.* Lets take a closer look at the benefits of collagen peptides from types 1 and 3 bovine collagen. As we age, our bodies produce less collagen. This decrease in collagen production can lead to a number of age-related issues such as wrinkles, joint pain and weak bones. Supplementing with collagen peptides can help to offset the decline in natural collagen production.* Collagen peptides are easily absorbed by the body and have been shown to promote joint health, bone density and skin elasticity.* There are many different types of collagen, but types 1 and 3 bovine collagen are most commonly used for supplements. Type 1 collagen is particularly good for skin health, while type 3 collagen is best for joint health. Both types of collagen are found in our bones, tendons, ligaments and skin. Hydrolyzed collagen from types 1 and 3 bovine sources provides the most benefit for overall bone, joint and skin health.* Collagen peptides from types 1 and 3 bovine sources are well-known for their roles in supporting bone, joint and skin health. Supplementing with hydrolyzed collagen can help to offset the decline in natural collagen production that occurs as we age.* Collagen peptides are easily absorbed by the body and have been shown to promote joint health, bone density and skin elasticity.* If you're looking for a supplement to support overall bone, joint and skin health, consider hydrolyzed collagen from types 1 and 3 bovine sources.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6480) Safe and Effective Joint Pain Relief: Natural Supplements That Work
Date:
July 21, 2022 10:41 AM
Do you suffer from joint pain? If so, you're not alone. In fact, according to the Arthritis Foundation, over 50 million adults in the United States are affected by some form of arthritis. And if that's not bad enough, it's estimated that by 2030, that number will grow to 67 million! The good news is that there are safe and effective ways to relieve joint pain without resorting to over-the-counter drugs. We'll discuss natural supplements like glucosamine, chondroitin sulfate, and MSM that have been shown to help rebuild cartilage and reduce inflammation. What is joint pain and what are the most common causes? joint pain is a common symptom that can be caused by a variety of conditions. The most common causes include arthritis, bursitis, and tendinitis. Arthritis is a general term used to describe inflammation of the joints. There are many different types of arthritis, but the most common are osteoarthritis and rheumatoid arthritis. Bursitis is the inflammation of the small sacs of fluid that cushion the joint, while tendinitis is the inflammation of the tendons that attach muscle to bone. Joint pain can also be caused by injuries, such as sprains and fractures. In some cases, the exact cause of joint pain cannot be determined. Treatment for joint pain depends on the underlying cause. How can over-the-counter drugs be harmful to your health? The wide availability of over-the-counter (OTC) drugs such as acetaminophen and ibuprofen can be a godsend when we are feeling pain or discomfort. However, it is important to remember that these drugs are potent medications that can also be harmful to our health if we take them inappropriately. Acetaminophen and ibuprofen are both nonsteroidal anti-inflammatory drugs (NSAIDs). NSAIDs work by reducing inflammation, but they can also have adverse effects on the gastrointestinal tract, kidneys, and liver. In addition, NSAIDs can interact with other medications that we may be taking, so it is important to speak to a healthcare professional before taking them. Although OTC drugs can be helpful when used as directed, it is important to be aware of the potential risks involved in taking them. What are some natural supplements that have been shown to help relieve joint pain safely and effectively? While there are a number of different supplements that have been traditionally used to help relieve joint pain, not all of them have been proven to be effective. However, there are a few natural supplements that have been shown to be safe and effective for this purpose. Glucosamine is a supplement that has been shown to help rebuild cartilage and relieve pain in osteoarthritis sufferers. Another promising supplement is chondroitin and msm, which helps to reduce inflammation and ease the symptoms of joint pain. Finally, fish oil supplements have also been shown to be effective in reducing inflammation and relieving joint pain. Turmeric, Boswellia, and CBD also reduce inflammation. When used together, these natural supplements can provide significant relief from joint pain. How do glucosamine, chondroitin sulfate, and MSM work to reduce inflammation and rebuild cartilage tissue? Glucosamine, chondroitin sulfate, and MSM are all natural compounds that have been shown to be effective in reducing inflammation and rebuilding cartilage tissue. Glucosamine is an amino sugar that is produced naturally by the body. It is a building block of cartilage, and it has been shown to stimulate the production of new cartilage. Chondroitin sulfate is a complex carbohydrate that is also found naturally in the body. It helps to keep cartilage healthy by protecting it from wear and tear. MSM (methylsulfonylmethane) is a sulfur-containing compound that is found naturally in some foods. It has anti-inflammatory properties and has been shown to promote the repair of damaged cartilage. Together, these three compounds can help to reduce inflammation and improve the health of cartilage tissue. How long should you take these supplements for maximum benefit, and when should you stop taking them if you don't experience results within a certain time frame? Many people take supplements in order to improve their health or address a specific health concern. But how long should you take them for? In general, most supplements should be taken for at least 6 to 8 weeks in order to see maximum benefit. However, some people may not see results until 12 weeks of supplementation. Of course, if you're working with a healthcare professional, they can help you determine when to start and stop taking supplements. But in general, 6 to 8 weeks is a good rule of thumb. Don't be afraid to add Turmeric or Boswellia to the mix. These herbs can enhance the effectiveness of the glucosamine, chondroitin, and MSM. Taking a natural supplement like glucosamine, chondroitin sulfate, and MSM can be an effective way to reduce inflammation and rebuild cartilage tissue safely and effectively. These supplements have been shown to be safe and effective for this purpose. When taken together, they can provide significant relief from joint pain. It is important to speak to a healthcare professional before taking these supplements if you are taking other medications, as there is potential for adverse effects. Be sure to take 1500mg of each in divided dosages though out each day for at least 6 to 8 weeks in order to see maximum benefit.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6419) Treat Your Arthritis Problems With Gelatin Amazing!!
Date:
June 04, 2017 05:14 AM
People who suffer with arthritis should consider the alternative and natural remedy of Gelatin. Gelatin is mostly know as an ingredient in candies and milk, but if used a teaspoon twice a day can considerably lower your pain level associated with arthritis. Gelatin has proteins made from animal cartilage bones and tendons. Most of the time we have gelatin in foods we would have never known. just by having this small amount 2 times a day can change the pain associated with arthritis in 4 to 6 weeks! https://www.youtube.com/watch?v=zum4zToUk4Q&rel=0Key Takeaways:
"Although there are medicines that reduce pain, these do not disappear forever."
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4765) Did You Know That Coconuts Are Healthy? If Not, Then Check This Out!
Date:
December 15, 2016 02:59 PM
Coconut meat is the rich white lining that is contained within the shell of a coconut. Coconut meat can be juicy and tender, or slightly thick and crunchy, to tough and fibrous depending on how long the kernel has been stored. Though coconut only grows in tropical regions of the world, it is now widely available in the American consumer market. And this is a fortunate thing as eating food products derived from coconut like coconut oil and coconut meat on a regular basis has profound positive effects to your overall health. Key Takeaways:
"Coconut also contains short-chain fatty acids and medium-chain fatty acids that have amazing benefits." Reference:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3652) How Does a Collagen Supplement Help With Joint Pain and Also To The Skin?
Date:
July 27, 2015 06:45 AM
Collagen is said to be the most abundant available protein in the body of humans. It forms fibers which are found in ligaments, cartilages, tendons and bones. It's a vital kind of protein in all mammals and it's about 30% the total amount of proteins in the body. Collagen fibers are responsible to ensure flexibility of the skeletal system. As ages increase as per from 25 years, collagen level decreases. This is the main reason why elderly people develop wrinkles which is a result of elasticity loss of the skin due to the decreased collagen level. Brittling of the nails, hair loss, stiffening of joints are also things that happen due to decreased collagen level. This makes collagen supplement very essential because it can prevent all that. Clinical related studies done over many years have shown clearly that collagen supplements is not only effective in stimulating the natural production of new collagen but also it does replace any missing collagen. Supplementation of collagen helps in maintaining and improving the health of the skin, arthritis, nails and hair and also relieving the joint pains. The collagen supplements mainly for joint pain and also arthritis are available in two major types: type II collagen and type I collagen. The type I collagen mainly helps to rebuild the cartilage in the joints. These will result in reduction of stiffness and pain which is majorly as a result of breakdown of these vital tissues. Presence of adequate cartilage will ensure improvements in joint movements. When it comes to type II collagen, it is actually the main protein which is lost during the aging process. People tend to prefer this supplement since it the collagen itself. Collagen is very important in joint health, although many people have thought of it as a wrinkle kind of treatment. Specific types of arthritis may cause the cartilage in joints loose elasticity and after sometime cause wearing of in areas that moves the most. This area are such as ankles, knees and wrists. With no collagen, there is not enough cartilage. Therefore, ligaments and tendons stretch to fill any missing cartilage which cause tremendous pain. You can always find collagen at any local or internet store, and be sure you will reap its benefits.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3183) Silica Supplements for Healthy Bones
Date:
April 19, 2014 05:36 AM
Silica
Health benefits of silica This mineral helps the body to develop the bones, the teeth, the cartilages, the tendons and the hair, giving further safety. Silica additionally gives the skin suppleness and the vascular dividers versatility. An eating regimen rich in silica can avoid osteoporosis, atherosclerosis (thickening of blood vessel dividers), skin wrinkling, diminishing and balding, broken nails and tooth rot. It makes the teeth, the nails and the hair to sparkle. Silica exists in lung tissue, so it is prescribed for the re-mineralization handle in tuberculosis patients. Since it serves to develop bone and cartilage, this mineral must not be absent from the eating methodologies of pregnant women and kids experiencing rickets. Additionally it helps acclimatize phosphorus, which is exceptionally imperative for the cerebrum wellbeing. Silica sources Luckily, silica is found in numerous nourishments we consume regularly, and particularly in leafy foods. A percentage of the wealthiest sources are the entire grains, the pieces of fruit and oranges, lemons, grapes, raisins, almonds, peanuts, nuts, grains by and large, cabbage, carrots, squash, green beans, cucumbers, mushrooms, onions, leeks, parsnips, weeds and radishes. From these, the entire grains hold a type of silica, which is not difficult to absorb. Corn shelled and results of it (white bread, for instance) do not hold silica. Besides, all refined or prepared items lose their supplements, including silica. Lager and nectar have additionally a substantial amount of this mineral in their creation. It exists even in water in diverse amounts, depending from on the land zone. Around the creature sustenance sources, fish is the particular case that holds silica. Since the nourishments holding this mineral are such a large number of, we can give our body, for the most part without issues, the everyday necessity. Silica lack is uncommon. It happens in individuals who consistently consume foods grown from the ground and the elderly, because the mineral is more troublesome to absorb with age. The vicinity of silica in the body is exceptionally imperative. The mineral is fundamental for calcium ingestion especially in the early phases of bone development, additionally for supporting skeletal wellbeing all around life. It is included in framing collagen and that is the reason it is vital for the strength of nails, skin and hair. Silica is additionally important to keep the adaptability of corridors, and assumes a real part in averting cardiovascular illnesses. It animates the insusceptible framework and deferrals the maturing procedure of tissues. The level of this mineral in the body diminishes with age. In this way, more seasoned individuals require a higher admission of silica, contrasted with ones that are more youthful.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3097) Does Camu Camu Fruit Have Healing Properties?
Date:
April 02, 2014 09:10 PM
What is a camu camu Inside a rainforest you will discover these types of bushes of which increase within the Rain forest avalanche. The actual fruit obtain from canoes as well as watercraft after that eaten fresh, dried or made into centred fruit juice. Some other part of these berries may be used as well as ingested in various means. Camu Camu contents and benefits The actual Camu Camu fruit boosts the manufacturing involving serotonin, the hormone that makes your senses beneficial. The higher level of vitamin G involving any vegetable that helps to improve your entire metabolic rate. There may be exploration evidence of which implies that the fruit features anti-oxidative as well as anti-inflammatory. In addition, it functions as anti-aging method. The actual large antioxidant part of this Camu Camu berry makes a strong compound with healthier skin care solutions. You will discover scientific studies that it has an anti cancer properties. The actual Camu will be adapted straight into makeup as well as healthy skin care because hugely rejuvenative talents. On the list of crucial ingredients for you to locate a wholesome life is having the necessary every day level of Nutritional G. Nutritional G is surely an ascorbic p, is normal water-soluble as well as has a critical role inside our each day eating plan. Contrary to almost all mammals, people are not able to by natural means develop Nutritional G consequently, we should acquire the idea inside our eating plan. The actual role of which Nutritional G does eat the body is always to synthesize collagen, and that is a significant structural component of tendons, ligaments, arteries and, as well as navicular bone. Nutritional G is significant since it helps to merge this ingredient component of this neurotransmitter, norepinphrine. Neurotransmitters usually are crucial for you to mind perform. Among other items additionally, it is related to help with our blood cholesterol levels plus the regularity involving gall stones. The word antioxidant goes in conjunction having Nutritional G. Antioxidants are critical within defending one's body coming from harmful free of charge radicals. The actual deficit involving Nutritional G in every day eating plan have been recognized for countless years for you to result in this generally dangerous illness involving scurvy. Any insufficient Nutritional G is even related to heart conditions. Nutritional G deficit in addition has been assigned to, cerebrovascular event, most cancers, cataracts, and in many cases guide toxicity. Final thoughts, include the ability from the Camu Camu fresh fruits antioxidant potency for you to fight free of charge radicals as well as re-balance these physiques systems. Combined with the berries, Camu Camu is easily transforming into a recognized super fruit, which includes many reasons as well as prices regarding man well being.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3086) What Is Gelatin Powder Good For?
Date:
January 29, 2014 04:54 PM
What is Gelatin?
Health Benefits of Gelatin Powder Gelatin powder has many health benefits.It is a source of protein and dietary collagen. It is composed of two amino acids-proline and glycine which many people do not consume adequately. This is because the amino acids are contained in organs of animals, fibrous tissue and in bones which a large population do not consume more often. These amino acids are important for proper hair, skin and nail growth. Gelatin powder helps in the recovery of joints when injured. Gelatin also provides building blocks for health joints. It has been noted that people with arthritis, joint pain and osteoporosis will see their situation improve when they take gelatine rich foods and supplements. It improves digestion as it binds to water making food move easily through the digestive truck. In this case the gelatine powder is usually used in form of a homemade bone broth. It supports hair, skin and nail growth. It will again protect your skin from wrinkles as your skin ages. Glycine which makes the large percentage in gelatine powder helps in speed wound healing and acts as an anti-inflammatory. It also improves sleep ease and quality. Believe it or not, it can also be used for weight loss. This is because it boosts metabolism when taken. Gelatin powder is used to naturally balance hormones in the body. High amounts of hormones like oestrogen in the body can cause infertility, inflammation and accelerate aging. Finally, gelatine is a cost-effective and nutritious way to get proteins in to your body. References:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2992) How Does Tart Cherry Fight Gout?
Date:
November 01, 2013 07:44 PM
Tart cherry studies
What can tart cherry do How can tart cherry be helpful in case of gout sufferers? In the first place, cherries have always been used in traditional medicine for promoting normal levels of uric acid within the blood – given that high blood concentrations of this heterocyclic compound lead to gout, modulating them using cherries will automatically prevent this affection from occurring and reduce the pain and swelling it causes.As mentioned above, there have been various studies targeting the effect of tart cherry on gout and according to the most recent one, consuming approximately 280 grams of cherries will decrease the uric acid levels with approximately 14% and increase the excretion of uric acid at the same time. Whether it is about regular tart cherry juice or medication, the effect will be mostly the same, reducing the pain caused by gout substantially. What tart cherry contains It should be noted that tart cherries contain approximately 10 milligrams of vitamin C in their composition, an organic (carbon-based) compound that can successfully ameliorate the inflammation and swelling produced by the gout and promote the uric acid excretion. Vitamin C acts primarily as an antioxidant, determining the human organism to eliminate not only the toxins from the tissues, but also the uric acid crystals that deposit in joints, tissues or tendons. Whether we talk about tart cherry juice or supplements, this natural solution does not involve any potential health risk for gout sufferers, lowering the erythrocyte sedimentation rate (which is an indicator of chronic inflammation) significantly and helping the blood stabilize the normal uric acid levels.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2869) What are the health benefits of silica gel?
Date:
April 27, 2012 03:15 PM
Silica Gel The inevitable process of aging does exhaust sources of silica in our bodies. This leads to brittle nails, bones, lifeless hair, wrinkles, and dry skin. The skin has collagen underneath which helps to enhance its beauty as well as elasticity. Silica helps provide a young and healthy look to the hair, nails and skin. It is associated with mineral absorption and may be combined with proteins or lipids. Silica can also come soluble in water or in free form. Silica is so important in the process of antibody manufacture and efficient in assisting to convert lymphocyte B into lymphocyte T, making it a very beneficial element for the immune system. Silica Promotes Collagen Production Silica quantities in our bodies are typically higher than the quantities of other vital minerals essential for a myriad of metabolic processes. A type of silica known as colloidal silica gel has very tiny microscopic particles of silica suspended in liquid. The gel can be taken in order to provide support to the connective tissues as well as to promote collagen formation in one's skin. Silica gel can also be bought in form of capsules. The gel may be mixed with juice or water. Health benefits Silica is a crystalline silicon or quartz and is found in abundant quantities in the crust of the earth. Silica gel is extracted from plants and is important for the bones, skin, cartilage, blood vessels, and tendons. Silica gel is found in very few kinds of foods and the amounts are usually sufficient for the needs of human beings. Silica gel must be replenished every day since it gets absorbed and then excreted rapidly. The gel is very important as it helps in the accurate absorption of vital minerals in our bodies and provides all healthy attributes for the collagen under the skin. Silica gel supplies proteins and lipids to our bodies and helps make the hair, nails, and skin have a more radiant look. Silica and osteoporosis Silica gel also helps to prevent and treat osteoporosis that is caused by aging. Calcium supplements alone cannot fight osteoporosis and have to be combined with silica gel. Osteoporosis decreases the density and mass of the bones, causing them to be fragile and porous. If one only takes calcium supplements, it may hasten the process of degeneration. Silica gel is very effective for pain relief and retention of the self-repairing abilities of our bodies. The connective tissues degenerate rapidly because they are not able to retain moisture for an extended period of time, thus silica gel works as the glue that holds them together. Silica And Blood Pressure Silica gel also helps to control high blood pressure for those at risk. While it lowers blood pressure, it helps promote and maintain the right blood pressure levels in the entire circulatory system. Doing this helps to bring normal circulation to the body. Silica gel is also recommended for people with various joint pains. From rheumatism and arthritis, silica nutrients replenish cartilage in the joints. After prolonged use, one can freely move their joints without feeling excessive pain or discomfort.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2639) What Are the Health Benefits Of Collagen Tablets?
Date:
April 10, 2012 06:57 AM
Collagen Collagen is one of the most important components involved in the formation of your body's ligaments, tendons, cartilage and muscles. As you get older, your body's ability to manufacture the required amount of collagen becomes lesser. Collagen tablets covers up for it by helping maintain the repair process. These tablets also have different benefits that you should consider and these benefits re given below: Improves blood circulation: this happens because collagen tablets improve the elasticity of blood vessels, making them stronger and this improved blood flow. It enhances healing of injuries: when our bodies cannot provide sufficient nutrients required to repair the body tissues, these tablets compensate for the loss. The structure of the bones, cartilages and other parts are also strengthened by this. It encourages the regeneration of muscle mass making recovery after sport related injuries faster. Keep Arthritis pains at bay: the disease associated with joint inflammation and painful mobility around the areas is referred to as Arthritis. Collagen tablets work at reducing this pain making movement around the joints more comfortable. Reduces the appearance of cellulite: when fatty tissues find way to the upper layers of the skin, dimples often occur. This is referred to as Cellulite. These tablets reduce this occurrence by rebuilding the destroyed fibres that allow cellulite to appear. Helps in reducing wrinkles: when our bodies no longer produce collagen, certain lines form on the places that move most, like our foreheads and joints. This is referred to as wrinkles. The tablets work by increasing the suppleness of the skin. Improves the hair structure: these tablets fight free radicals which often affect the texture and growth of our hair. Replacing this component in the shaft of your hair will give your hair better appearance. It is advisable to start taking these tablets from as early as thirty years as this will prevent the onset of the above conditions. It also makes your skin look younger by preventing wrinkles. One should use these tablets because its absorption occurs naturally through the blood stream, making it possible for your body to decide its destination. If you are an athlete, this is just the thing for you as it facilitates the healing of wounds making it possible for you to be back on the field within a short time. The tablets can help soften your stiff joints if you find it hard to exercise because of that. If acne is your problem, then you won't have to worry, because this drug works with your skin's keratin to produce the best results ever. It is also said to have an effect in weight loss. One thing that you should note is that collagen tablet works best on an empty stomach, so for the best results, take it early in the morning or before meals. These tablets are cheap and easy to find. They contribute greatly to your health and overall appearance. Now that you know, take that short trip to the nearest chemist and take control of your future life! Collagen tablets are a good way to start.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2631) GLUCOSAMINE: Origin and Action of Mechanism
Date:
February 06, 2012 01:08 PM
Glucosamine is an amino sugar made from glucose and amino acid glutamine. It is a monosaccharide that is found naturally in healthy joints, cartilages, ligaments, muscles and tendons. It helps in the formation and repair of cartilage and other body tissues. Glucosamine is available in the form of dietary supplements, cosmetics and sports drinks. Let us find out about the history of glucosamine and its role in repair and treatment of joint disorders. HISTORY of GLUCOSAMINE: Glucosamine was first discovered in 1876 by Dr. Georg Ledderhose. It was prepared by hydrolysis of chitin with Hydrochloric acid. Later on it was developed in sulphate blend. Since then, it has been studied multiple times and in multiple ways to find out its potent health benefits. It has been used clinically in Europe since 1960s. In 1971, researcher K. Karzel glucosamine HCl stimulated the production of glycosaminoglycan layer, which helps in protecting cartilages, ligaments and tendons from normal wear and tear. It became popular in United States in the mid 1990s with the publication of popular bestsellers such as 'The Arthritis Cure' by Jason Theodosakis. Now it has become the most popular selling dietary supplement with sales of $200 million per year. Glucosamine is naturally found in the body and can be synthetically made from the natural sources of chitin that is found in sea creatures such as shells of shell fish, bones and bone marrow. How does Glucosamine Works in reducing Joint pain? Our body's ability to produce glucosamine decreases as we age. Hence after any kind of injury cartilage, spinal discs and joints, the body may not be able to heal optimally. Aging and glucosamine depletion in the body leads to joint degradation. However, glucosamine supplementation can support cartilage and CT-integrity limiting degeneration. Glucosamine supplements do not work like NSAIDS, which are known to have anti-inflammatory and analgesic effects on the body. The exact mechanism of significant analgesic effect of glucosamine supplements is unknown but according to various studies, glucosamine has no effect on cyclooxygenase system. Studies have shown that glucosamine stimulates synthesis of proteoglycan in a dose dependent manner. It helps in stimulating the production of cartilaginous matrix, hence counteracting the degrading loss of cartilage in case of arthritis or injury. Several important studies demonstrate the role of glucosamine in stabilizing cell membranes, inhibit lysosomal enzymes and reduce the generation of oxygen free radicals by macrophages. It may inhibit interleukin 1 induced nitric oxide activity that leads to chondriotic cell death. Hence it increases aggrecanase activity that helps in preservation of proteoglycan. Glucosamine along with Chondroitin sulphate stimulates synthesis of cartilage precursors as well as synovial fluid. They also limit the degradation of existing cartilage in any loss of joint integrity. This non rapid acting drug has many beneficial effects in reducing the symptoms of osteoarthritis. It is a powerful joint repairing supplement that rebuilds joint cartilage. Glucosamine supplements have been thoroughly evaluated to find out any potential side-effects. However, it has been proved that it does not have any of the side-effects of NSAIDS, surgery or opiods.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2555) What are the Essential Amino Acids we must get from our Diet to Survive?
Date:
August 17, 2011 12:13 PM
Amino acids or the building blocks of protein are very important in overall functioning of the body. Proteins, to mention, are responsible for the build up of most of our body parts specifically our muscles, ligaments, tendons, organs, tissues, glands, nails and hair. Moreover, the repair and preservation of those parts still rely on proteins. Amino acids can be of two different forms which are the non-essential and essential. On this selection, we will be focusing more on the latter. Essential amino acids are those which cannot be produced by the body therefore it has to be supplied through our diet. This category of amino acids includes tryptophan, lysine, methionine, valine, leucine, isoleucine, threonine and phenylalanine. Tryptophan, which is a precursor to serotonin and melatonin, can be acquired from peanuts, meat, turkey, fish, milk, dried dates, cottage cheese, banana, oats and chocolates. A deficiency of this can bring up serious neurological problems, depression, anxiety and sleeping difficulties. Another essential amino acid is methionine. The production of sulfur and other compound needed for a healthy growth and metabolism depends on the presence of this amino acid. Fish, whole grains and dairy are its sources. Lysine, which is effective in the treatment and prevention of herpes, is present in soybeans, green beans, lentils, spinach and amaranth. Low levels of lysine can also compromise the levels of niacin and this leads to pellagra. Tissue healing, muscle metabolism and keeping the equilibrium of nitrogen levels in our body are the functions of valine. It has proven to be efficient in the treatment of liver and gallbladder disorders. Deficiencies that results from drug addiction are can also be reversed by this amino acid. Its sources are peanuts, soy proteins, dietary products, grains, meat and mushrooms. Leucine can be obtained from chicken, fish, cottage cheese, lentils, peanuts and sesame seeds. It functions in muscle protein build up and is the main medium in tissue building process. Inability to acquire such makes a person prone to protein wasting since leucine, together with valine and isoleucine, serves as energy and protein reservoirs. In boosting energy levels, blood sugar regulation, muscle build - up and repair as well as hemoglobin development, isoleucine has shown its relevance. Its dietary sources are fish, poultry, beef, dairy, eggs, lentils, seeds, soy, almonds and wheat. Isoleucine deficiencies may result into neurological disturbances such as confusion, depression, irritability, fatigue, headache and dizziness. Threonine is significant in synthesis of antibodies. Beans, nuts, seeds, dairy, poultry, eggs and beef are rich in threonine. A low level of this amino acid causes disorders of the skin and weakness. Adrenaline and noradrenalin which are stimulates the central and peripheral nervous system requires phenylalanine to perform their function. Phenylalanine can be acquired from peanuts, seeds, almonds, lima beans and dairy. Liver damage, weakness, skin lesions, lethargy and slowed growth are results of its deficiencies. In summary, our body needs networks of essential amino acids for its proper functioning. Eating healthy foods and living a healthy lifestyle is the secret towards maintaining your optimum general health.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2396) Can Dietary Collagen Help the Skin and Joint Tissue?
Date:
June 30, 2011 10:45 AM
Collagen and Your Health
Collagen is the most common form of protein in humans and other mammals. It is a major constituent of the extracellular matrix that provides structural support to animal cells from the outside. It displays great tensile properties, which is responsible for the strength and elasticity of the skin. Since it is a component of fibrous tissue, it is also found in ligaments and cartilages that make up joint tissue. Dietary collagen has long been postulated to contribute to the biochemical composition of cells present in the skin and joints. Proponents of collagen supplements believe that dietary collagen is assimilated into the extracellular matrix and fibrous tissue. The scientific community has been doubtful about the efficacy of topical applications of collagen, but oral supplements have been promising in clinical trials. Molecular collagen is composed of polymers of amino acids linked by peptide bands, which are too big at the cellular level to get absorbed through skin. On the other hand, intestinal absorption of dietary collagen remains a matter of controversy. That being said, nutraceutical companies have developed formulations of supplements that facilitate the best possible absorption rates and better bioavailability. Tough bundles of collagen fibers comprise several polypeptide chains of fibrous structural proteins. All fibrous tissues have cells and extracellular matrix in between. High concentrations of collagen found in cartilages, ligaments, tendons, fascia, and even bones give these fibrous tissues tensile strength, the reason why the joints are capable of bearing a certain level of longitudinal stress without tearing apart.
Structural proteins make up the outer layer of the human skin and its appendages, such as the scalp, hair, and nails. The most important of these proteins are collagen, keratin, and elastin. Collagen fibers are responsible for the tensile properties of the skin. Keratin provides strength whereas elastin exerts an elastic effect. Collagen fibers affect the process of healing and its degradation leads to wrinkles. Oral route of administration is believed to produce the health benefits linked to dietary collagen. While researchers have ruled out the health claims tied to collagen creams and lotions, they have reported encouraging results about dietary collagen. In fact, collagen supplements utilized in the management of rheumatoid arthritis and treatment of skin disorders have produced significantly positive outcomes. One clinical trial that involved more than 200 participants diagnosed with rheumatoid arthritis point to the medicinal potential of collagen as an adjunct treatment for rheumatism and osteoarthritis. There was a noticeable decrease in joint pain, morning stiffness, and restrained mobility, which were noted as statistically significant. For this reason, supplementation of collagen has attracted more research. Dietary collagen is now becoming increasingly visible in the nutraceutical industry in that sales have increased in the past few years. It has become the subject of numerous studies well underway, and as such developments in collagen supplementation are expected to produce formulations specialized for higher bioavailability. The good news is dietary collagen has not been linked to any adverse effects. Get some collagen today and feel the difference it can make in your diet!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2354) How Does Cherry Fruit Extract Help with Gout?
Date:
March 07, 2011 04:39 PM
Cherry fruit extracts contain the micronutrients and phytochemicals found in cherries. They are available as supplements widely touted to display antioxidant and anti-inflammatory properties. Cherries, the fruits, are in fact very high in anthocyanins, which have a long association with the prevention of inflammation, even including the type that results in most known cardiovascular diseases. Also, research on anthocyanins in connection with its chemopreventative potential has yielded the most reliable public data. Individuals suffering from gout will definitely benefit from cherry fruit extracts as supported by an abundance of reports and anecdotal evidence concerning its efficacy.
Stabilizes Metabolism of Purine NucleotidesThe development of gout is greatly attributable to an anomaly in the metabolism processes involving purine nucleotides. A class of organic compounds classified as purines is necessary for life and present in many chemical reactions. They are a major component of ATP, the primary energy of cells, and several nucleotide bases of DNA and RNA are purines. The problem lies in its final metabolic product, uric acid, which at high levels condense into urate crystals that are deposited in tendons and ligaments, as is the case with gout and tophus. Cherry fruit extracts bring about twofold effects. First, they stabilize purine metabolites, notably uric acid, and, second, they facilitate the effective excretion of uric acid. If you consume a lot of foods high in purines such as animal products, especially beef, pork, and seafood, taking cherry fruit extracts will make sure that the uric acid they produce gets out of your system. Affects Releases of Inflammatory Mediators While high levels of uric acid is the causation of gout attacks, the painful inflammation that ensues is triggered by an entirely different group of endogenous compounds in the employ of the immune system. Eicosanoids have long been identified to precipitate pain not only during gout attacks, but in all inflammatory responses of the human body. These compounds are released locally by the cells around the joints containing urate deposits in an attempt to fight off the degenerative effects of uric acid on the surrounding tissues. They deal with the joints the same way they get rid of pathogens during infections, bringing on the redness, swelling, and pain characteristic of gout. A group of bioflavonoids called anthocyanins that are known to interfere with the releases of eicosanoids are abundant in cherries, and intake of cherry fruit extracts deliver these flavonoids into the region of pain. Normalizes Acidic Digestive Environments Cherries belong to the group of foods that are alkaline forming. With gout thriving in an acidic setting, it is just prudent to carefully reassess your diet and cut down on foods high in purines. Not surprisingly, your doctor may tell you to minimize consumptions of meat products especially if you suffer from recurrent gout attacks. Cherry fruit extracts rebalances the pH level of your gastrointestinal tract, and supplementation will keep your body in an alkaline state in the long run, protecting you not only against gout but also against the aging process.
If you suffer from gout or other uric acid buildup disease, give cherry fruit extract a try today!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2248) Glucosamine and Joing Pain
Date:
April 05, 2010 04:34 PM
A decline in the amount of glucosamine production occurs along with the normal aging process. This compound is involved in the natural cushioning of the joints, which means that damage and pain can result from a lack of glucosamine. When the natural cushion is gone, the bone and cartilage may rest against each other, which in turn causes deterioration. Not only can this occur in the joints, but it can also occur in the spinal column.
Glucosamine sulfate has proven to be an effective treatment for osteoarthritis. In fact, some have found that this treatment works better than conventional therapies. This is because it does more than just mask the pain. Rather, it actually aids in rebuilding and stimulating joint repair. Also, glucosamine Scientific evidence shows that glucosamine metabolism is altered when osteoarthritis is present within the body. It has been found that glucosamine supplements provide an effective treatment for this condition. Studies, up to this point, have found substantial improvement in those individuals who are treated with glucosamine. There is little risk, if any, involved in the use of glucosamine for the treatment of osteoarthritis. Studies have shown that this compound is very safe and does not possess any known precautions or risks. One study even determined that glucosamine sulfate has the ability to help stimulate the defense mechanisms that are present within the stomach lining. Pain and anti-inflammatory medications, on the other hand, often cause stomach problems such as ulcers.
Glucosamine sulfate has been shown to be an essential part in treating osteoarthritis. Scientific results showed significant improvement in swelling, pain, and degeneration of joints with the use of glucosamine sulfate. Not only is this compound important for reducing the symptoms that are involved with osteoarthritis, but the supplement has been found to actually reverse the degenerative process and induce healing. This compound should be considered to be a form of treatment for osteoarthritis.
It should be noted that when taking this, or any other supplement, one should consult their health care provider before beginning any type of supplementation. Glucosamine may not be recommended in some situations. Do not take glucosamine without first talking to your doctor if you are pregnant or could become pregnant. Similarly, be sure to consult your doctor first if you are breast feeding a baby. For more information on the many beneficial effects provided by glucosamine, please feel free to contact a representative from your local health food store.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2135) Fight Cold Sores And Build Collagen
Date:
April 29, 2009 10:18 AM
Lysine is an essential alpha-amino acid, in that it cannot be biosynthesized by the human body, and therefore must be taken in your diet or as a supplement. It is synthesized in plants from aspartic acid, and metabolized in the body to produce acetyl-Coenzyme A (acetyl-CoA). Before discussing its action on herpes, we shall first have look at how Lysine helps with the formation of collagen. Collagen is a protein that is produced in the body from lysine and proline, another amino acid. In fact the primary role of amino acids in your diet is as building blocks to form the much larger protein molecules. Collagen is fibrous, and forms the connective tissue such as cartilage, ligaments, tendons, blood vessels and skin. Even the external parts of the ears. It literally holds our skeletons together, and wraps the whole body up in skin, so if we had no collagen we would literally fall apart! Collagen is also used by body cells to form the matrix that the body cells use to attach to each other and is one of the most important types of tissue in your body. It is so ubiquitous that over 30% of the protein contained in your body is collagen, and it is designed for its structural strength as opposed to its ability to take part in chemical reactions as other proteins are. Lysine and Vitamin C are essential for the maintenance and formation of collagen. There is not a lot of lysine in collagen - only about 4%, but it is very active in the cross-linking that forms the fibrils of collagen. Fibrils are the hair-like structures formed in a triple helix arrangement by three protein chains twisting round one another. The fibrils are bundled together in a straight line that has amazing tensile strength. The tensile strength of collagen is, weight for weight, stronger than steel! In order for lysine to take part in this process effectively, some molecules have to be hydroxylated and others oxidized, forming aldehydes. Things can go wrong here, and deficiencies in the metabolic process can lead to some heritable conditions, or diseases of connective tissue. Among these are lathyrism, Cutis-Laxa and the Menkes kinky hair syndrome. However, lysine is a very versatile amino acid, and not only is it necessary for the biosynthesis of all proteins, but is also heavily involved in the production of enzymes, hormones and antibodies. It is an important component of the calcium absorption process, and also, as previously stated, can be used in the treatment of herpes simplex. This form of herpes is known commonly as 'cold sores', and is a result of the activity of the herpes virus. Viruses do not reproduce in order to ensure the 'continuation of the species', but replicate. In order to achieve this it requires the help of another amino acid, arginine. This is a common amino acid whose sources include grains, seeds, peanuts, raisins and chocolate. Lysine and arginine competes for the absorption and entry of tissue cells, and reduces the strength of arginine, so preventing the growth of herpes. For this reason a supplement of lysine can be used to reduce the effects of the herpes simplex virus, and lessen the symptoms of the cold sore. However, it is not only cold sores but other forms of herpes that lysine can help to relieve. Herpes zoster is a virus that causes shingles. This virus is generated by the reactivation of the dormant varicella-zoster virus left in the tissues after chickenpox. It is a recurrent condition, and lycine can help to reduce recurrences as well as its severity. Apart from being an effective defense against herpes, and forming collagen, the amino acid imparts several other benefits to the human body. Among these is osteoporosis. L-lysine is involved in calcium absorption in the intestine, and also helps to reduce the loss of calcium in the urine. In osteoporosis we have to try to make every calcium molecule ingested in the diet to be incorporated in the bone structure. L-arginine can work with lysine to enhance the activity of the body cells that produce bone. Canker sores are often mistaken for cold sores, but they are actually quite different. They are small sores inside the mouth, and appear in the form of very painful ulcers. The cause is unknown, but is believed to be a virus, and lysine appears to help the condition. Although there have been no proper clinical tests carried out on its use as a remedy for canker sores, lysine appears to help, and a supplement is recommended as a treatment by many doctors. It will do no harm, and anybody suffering from these tiny but painful sores will try anything. Although lysine deficiency is rare, it can occur, particularly amongst those observing a vegetarian macrobiotic diet, and also in athletes who frequently undertake vigorous exercise, especially with too little recovery time. The effects of a deficiency are fatigue, nausea, appetite loss, anemia, slow growth and kidney stones. The latter is likely due to a failure to absorb calcium, that L-lysine promotes, and the formation of calcium oxalate and other insoluble salts in the kidney. Dietary sources include beans and other legumes, and although it should be available in cereals, baked foods and doughnuts, for example, the carmelization of sugars binds the lysine to the sugar, and so reducing its bioavailability. However, you can also get it in cheese, eggs, tofu and red meats. If you are taking an arginine supplement, you should consult your physician prior to taking lysine. The reason for this is that lysine and arginine share biochemical pathways, and arginine can reduce the effective concentration of lysine. However, it has not been tested by the FDA, nor approved, and any use is at your own risk. This risk appears to be very small, although its manufacture is not regulated. However, do not let this bother you: the proof of the pudding is in the eating as they say. Many have found lysine to be effective with collagen or herpes problems, and a supplement of between 3,000 and 9,000 mg per day is recommended for those with herpes viral infections. It is not recommended for children under two years old. Lysine is available at your local or internet health food store at discount prices. Look for name brands to ensure purity and quality of the product you purchase. Another Great Cold Sore Remedy is Red Marine Algae!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1998) Inosine
Date:
December 19, 2008 12:35 PM
Inosine is a specific type of glycosylamine that consists of a base bound to a deoxyribose or ribose sugar. This type of glycosylamine is referred to as a nucleoside, others being adenosine, thymidine and cytidine. It is available naturally in brewer’s yeast and major organ offal such as liver and kidney. It’s function in animal biochemistry is in the production of ATP (adenosine triphosphate), often known as the molecule of energy, that is essential for the generation of energy by the mitochondria in our body cells. It’s biochemistry is described below. Inosine is synthesized as inosine monophosphate by means of a complex series of biochemical reactions. The inosine monophosphate is a precursor for adenine, a nucleotide and purine base that reacts with ribose to form adenosine. This is another nucleoside that can be phosphorylated to produce adenosine monophosphate (AMP), the diphosphate (ADP), the triphosphate (ATP) and cyclic adenosine monophosphate (cAMP). Each of these is involved in the metabolism of energy in the mitochondria. Glucose undergoes a number of enzyme-catalyzed reactions in the presence of oxygen that ultimately breaks it down to water and carbon dioxide, plus at least 36 molecules of ATP via glycolysis and then the Krebs cycle. The ATP reacts with water to release energy and form ADP. The ADP can then be phosphorylated to produce more ATP. The starting point of all of this is inosine, and it is little wonder this nucleoside is used by athletes to help boost their energy. Not only that, however, but adenine is also the precursor of amino and nucleic acids responsible for the generation of RNA and DNA, and it is also responsible for the production of many coenzymes. These provide other opportunities for its use elsewhere in medicine, and it has also been found to possess other medical properties that will be discussed later. It was in the 1970s that inosine was first used to boost athletic performance due to its part in the generation of the energy needed by every muscle in the body. Its use began in eastern countries, although evidence at the time did not support the theory. Nevertheless, this did not deter its advocates, and inosine continued to be used by athletes, a practice that has now spread world-wide. It has been found to be a metabolic activator, in that it supports metabolism through the generation of energy. Inosine has been used by power lifters for heavy weight training to increase the capacity of the blood to carry oxygen, and strength athletes, particularly of the Eastern Bloc, used it from the mid 1970s onwards. Inosine appears to increase the natural ability of the body to handle strenuous workouts, although there is no scientific proof of this. However, those that use it claim an increased ability to carry out intensive training workouts and an improvement in their competitive performance. The nucleotide can penetrate the cell walls and get to where it is needed to take part in the metabolism of energy through the production of ATP. Now, however, inosine has an entirley different application in medicine. Studies have shown that it could support those suffering from MS (multiple sclerosis) and strokes through its pereceived neuroprotective properties. It appears to promote axonal rewiring, where undamaged neurons appear to grow new connections with damaged areas of the brain, and undamaged neurons seem to branch out to replace some of the damaged neurons. Inosine is also an intermediate in the production of uric acid through purine and purine nucleoside degradation. Uric acid is a powerful antioxidant, particularly in respect of peroxynitrite, a nucleophile that causes the type of axonal degradation that is associated with multiple sclerosis. It thefore helps in two ways: through the production of uric acid, and in promoting axonal rewiring that can improve brain function in patients. Another potential medical use for the substance is based upon the discovery that inosine and related compounds can act as powerful anti-inflammatories through their effect on inflammatory macrophage proteins. Certain conditions can cause the release of these macrohages, and where it is an undesirable side-effect, inosine can be administered to prevent it occuring. Inosine appears to inhibit the production of pro-inflammatory cytokines without inhibiting anti-inflammatory cytokines. It appears to do so extracellularly, although the effect can be reversed by the blockading of adenosine receptors. However, it is a convenient way of avoiding this sometimes serious condition, which is a natural function of the immune system, without affecting any other part of that system’s essential work. It is not an essential nutrient, since it is synthesized biochemically, but a supplement of inosine is certainly worth taking if you want to increase your ability to carry out athetic exercise requiring a high energy output and increased blood oxygen availability. It also helps to reduce recovery time, and proponents of its use claim that it enables you to exercise at a higher level for longer. Although the medical evidence for this is scant, not a lot of work has been done in trying to establish it, and those that use inosine in this way swear that it is effective. The theory certainly indicates that it should be effective in helping to produce more energy, and also that it should be able to make more oxygen available, and some athletes have been taking it for decades with excellent results. There are no known side effects of its use, although pregnant women and nursing mothers are recommended not to use it, as with many other health supplements the pathology of which have not been closely studuied. As with any supplement, you are highly recommended to consult your own doctor or physician when taking any supplement, particular if you have a current medical condition or are taking prescriptive medicines. If you are predisposed to gout, and some people are, the uric acid it produces can render inosine unsuitable. Uric acid reacts with calcium to produce the sodium urate that is deposited on the cartilage and tendons of the joints, particularly the big toe. It is a very painful condition, so those that have suffered gout in the past should not take inosine as a supplement.
Otherwise, its effect on your athletic performance might be academic!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1951) Hyaluronic Acid can help Restore Joint Function
Date:
December 01, 2008 10:03 AM
Hyaluronic acid, also known as hyaluronan, is one of the main components of the extracellular matrix of connective tissue and joints, and is one of the main chemicals contained in the synovial fluid that lubricates your joints. Before we discuss how it can be used to help restore the function of damaged joints, let's have a look at what causes joint pain, and why joints can break down long before their time. You might have heard that arthritis is an inflammatory condition, or that it is due to the immune system. This is true to an extent, and rheumatoid arthritis is an immune system problem, although osteoarthritis is a different problem altogether. Arthritis is not the only cause of joint pain of course, but is by far the most common cause. As already inferred, there are two forms of arthritis, each with a different basic cause. Osteoarthritis is the most common form of joint disease, and is largely due to wear and tear, injury or can be hereditary. However it is usually initiated by damage, the joint surface becomes roughened and the bone around the damaged area gets thicker to compensate. A joint is where two bones meet, and not all joints move. You have the fixed joints in your skull, for example, and those between the ribs and the spine. However, arthritis generally affects the joints associated with movement, mainly the knees, hips, fingers, toes and elbows. The ends of the bones are covered with a thin layer of cartilage, which can absorb shocks and both cushion the joint and allow the ends of the bones to move smoothly over each other. Round each joint is a membrane known as the synovium that is filled with the thick synovial fluid, which lubricates the cartilage. The bone ligaments hold them close to the joint, and prevent them moving too much and dislocating. Finally, the joint is completed by the tendons that attach the muscles to the bones they control. Osteoarthritis causes a joint to deteriorate: the cartilage becomes rougher and wears, and the bone beneath the cartilage gets thicker. At the edge of the joint the bone tends to grow outwards, forming spurs and the synovium swells producing extra synovial fluid. This causes swelling and pain, and ultimately the joint can be damaged beyond repair. This process takes a number of years to reach a stage whereby pain and discomfort are felt. Before that situation occurs, however, the joint tries to repair itself, and hyaluronic acid can take part in this process. It is mainly involved in the reparation of connective tissues such as cartilage, although there are other connective tissues which hyaluronan has been found to repair. These include skin, eyes and heart valves and hyaluronic acid can arguably be used to help repair all of them. However, it is joint tissue with which we are concerned here, and hyaluronan is an important component of articular cartilage: the type of cartilage involved in movement (knees, hips, etc), as opposed the type that forms your nose or the external part of your ears. It is believed that injections of hyaluronic acid can help to repair damaged articular cartilage. However, osteoarthritis is only one of the two forms of arthritis. The other is rheumatoid arthritis, and this is much more sinister. Rheumatoid arthritis is caused by the attack of your joints by your own immune system, although why this happens is unknown. The most likely theory is that certain infections trigger the immune system, and it then proceeds to attack the synovial joints. Cytokines are responsible for inflammation of the synovial fluid, which can also cause fever, loss of weight and appetite, and inflammation of the blood vessels. The body tries to generate more synovial fluid which causes swelling round the whole joint, putting pressure on the damaged areas, and generating even more pain. The inflammatory response commences and the whole area becomes seriously painful. The smaller joints are most commonly affected, such as the fingers and toes, but it can progress to the elbows, hips and the knees. The joints become red, swollen and finally too stiff to be used. The sinusitis eventually leads erosion of the joint and deformation. Because hyaluronic acid behaves like the synovial fluid, it is believed that it can be used to treat both forms of arthritis. It is a glycosaminoglycan, an unbranched polysaccharide of the same type as chondroitin sulfate that is commonly used to treat arthritis. It can be used to increase the viscosity of the synovial fluid, and render a more effective lubricant. However, it is in treatment of osteoarthritis that hyaluronan is most likely to find success. It is used to improve the viscosity of the synovial fluid, so providing increased lubrication to the joint and helping reduce the pain. In fact it not escaped notice that those who eat a diet rich in hyaluronic acid tend to live longer and look younger than those that do not do so. Commercial preparations are currently in use or under evaluation for disorders such as glaucoma, fractures, and detached retinas, damage to cartilage, healing ligaments and osteoarthritis. These last three are particularly of interest to arthritis sufferers, and signs are that they are effective with many cases. However, it has also been established that smoking cigarettes can negate the effect of hyaluronic acid, and excessive levels of Vitamin C can also degrade it. Estrogen treatment, however, can enhance its effect in repairing connective tissue. Zinc deficiencies have also been found to have negative results, so make sure that these factors are addressed if you are using hyaluronic acid to treat arthritis. Something to keep in mind if you are taking hyaluronic acid orally is the size of the molecule. It is a very large molecule, and suffers from the same absorption problems as chondroitin sulfate. There are smaller hyaluronan molecule versions available if you can find them, that improve the absorption through the intestine, but if not then the dose will generally be greater than expected due to the low absorption levels due to the molecule being too large to be easily absorbed through the tissues into the bloodstream.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1942) Vitamin C
Date:
August 12, 2008 01:37 PM
Vitamin C is the most widely taken nutritional supplement on the market and is available in a variety of forms, including tablets, drink mixes, crystals in capsules or bulk powdered crystals. Vitamin C is present in mother's milk and, in lower amounts, in raw cow's milk, with pasteurized milk containing only trace amounts. This vitamin is most present in the liver and least present in the muscle but needed through out the body. Vitamin C is required for the synthesis of collagen, an important structural component of blood vessels, tendons, ligaments, skin, and bone. Vitamin C can regenerate other antioxidants such as vitamin E; in the body vitamin E can regenerate C as well. This vitamin is required for the growth and repair of tissues in all parts of your body. Relatively large doses of vitamin C may cause indigestion, particularly when taken on an empty stomach. It has been shown that smokers who have diets poor in vitamin C are at a higher risk of lung-borne diseases than those smokers who have higher concentrations of Vitamin C in the blood. Biological tissues that accumulate over 100 times the level in blood plasma of vitamin C are the adrenal glands, pituitary, thymus, corpus luteum, and retina. Studies suggest the presence of large quantities of sugar either in the intestines or in the blood can slow absorption of this vitamin. Several studies have demonstrated a blood pressure lowering effect of vitamin C supplementation. Also, when consumed in high doses it appears to interfere with the blood thinning effects of warfarin by lowering prothrombin time, as noted in case reports in the 1970s so consult your doctor if on medications.. In one Study, researchers instructed patients with documented coronary artery disease to take a single oral dose of either 2 g vitamin C or a placebo. Results, the researchers discovered that high doses of vitamin C can help prevent blood platelet sticking and fight cholesterol oxidation. Also, researchers discovered this vitamin can reduce the formation of potentially carcinogenic nitrogen-containing compounds in the stomach, offering protection from stomach cancer, researchers have reported. French and German researchers found that vitamin C appeared to keep cells in the blood vessel wall from dying. The researchers, who studied immune indicators, such as serum immunoglobulin and neutrophil phagocytosis (how well your white blood cells can engulf and digest foreign bodies), concluded that vitamin C exerts a remarkable immuno-modulating action, in other words, improved immune function in all those who consumed vitamin C on a regular basis. What are deficiency symptoms for vitamin C? Scurvy is a disease resulting from lack of vitamin C, since without this vitamin, the synthesized collagen is too unstable to perform its function. Scurvy was common among those with poor access to fresh fruit and vegetables, such as remote, isolated sailors and soldiers. The amount of vitamin C required to prevent “chronic disease” appears to be more than that required for prevention of scurvy which is 30 – 60 milligrams per day. Based on scientific research, vitamin C also appears to improve oral absorption of iron, which is good news for those that are anemic. Half of us in the United States will die from heart disease. The foundation of heart disease is atherosclerosis, the narrowing of our arteries with plaque. Treatment with vitamin C has consistently resulted in improved dilation of blood vessels in individuals with atherosclerosis as well as those with angina pectoris, congestive heart failure, high cholesterol, and high blood pressure. Researchers believe this protection from cell death could explain previous study findings which suggest that vitamin C benefits blood vessel function in people with congestive heart failure. Vitamin C supplements are also generally regarded as safe in most individuals in recommended amounts, although there are rarely reported side effects including nausea, vomiting, heartburn, abdominal cramps, and headache. In addition, this vitamin is required for the synthesis of l-Carnitine, a small amino acid that is essential for the transport of fat to cellular organelles called mitochondria, for conversion to energy. If you have chronic fatigue syndrome, vitamin C may help by boosting energy production through the mitochondria.
Therefore, as in many studies of vitamin C intake and cardiovascular disease risk, it is difficult to separate the effects of vitamin C on stroke risk from the effects of other components such as diet and the consumption of fruits and vegetables. As with all dietitians an emphasis on the benefits of a diet rich in fruits and vegetables is important to maintain a healthy cardiovascular system. If one can not consume fruits and vegetables on a daily basis then supplementation of vitamin C is need in either capsule of tablet to fight the risk of disease.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1863) Cetyl Myristoleate
Date:
May 08, 2008 03:47 PM
Cetyl myristoleate is a fatty acid ester used largely as a dietary supplement to support joint mobility and the immune system. Chemically it is a natural hexadecyl ester of cis-9-tetradecanoic acid, an unsaturated fatty acid commonly known as myristoleic acid. The acid is found naturally in fish and whale oils, and also in butter and kombo butter from the kombo nut. The ester is of a buttery consistency at normal room temperatures, and turns waxy when cooled, and it has no known uses other than as a health supplement, particularly for the treatment of arthritis and other inflammatory and immune system problems. The substances appear to have similar therapeutic characteristics to unsaturated essential fatty acids, but with a stronger and more long lasting effect. It also appears to work in three distinctly different ways in that it acts as a joint lubricant, supports the immune system and functions in the same way as essential fatty acids. Arthritis is a disease that has reached epidemic proportions worldwide, and it is estimated that more than 50 million Americans are affected by it. Until recently it was believed to be a disease of the aged, or associated with physical injury, but is now known to be more complex than that, with many manifestations and causes. Because of this, no single treatment is effective with all forms of arthritis, but cetyl myristoleate is the new kid on the block that is believe to make a significant contribution to the treatment of non-infective forms of the disease. However, it was not always known, and a search in the textbooks for cetyl myristoleate prior to 1977 would have yielded nothing. Why 1977? It started with Harry W Diehl, a sugar chemist with an interest in the treatment of arthritis. While carrying out research on arthritis in mice, he was working on thin layer chromatographic analysis of a methylene chloride extract of macerated mice. He noticed a separation that was unknown to him, which was subsequently identified as cetyl myristoleate. He had been unable to induce arthritis in mice, and believed that if he found out how to do that, then he should also be able to establish what made the mice immune to the disease, and so establish a cure. He soon established that it was this cetyl myristoleate circulating in the blood that protected the mice, and then found a way of synthesizing it in the lab by esterifying myristoleic acid. Since the compound was unknown at that time Diehl patented it in 1977, hence the date. Apart from in mice, it has subsequently been found only in whale oil and in one of the glands of the male beaver, with no other known sources at the time of writing. There have been several studies that have supported the effect of cetyl myristoleate on arthritis, the first human study being in 1995 when 46 out of 48 arthritis patients showed significant improvement in articular mobility and reduction in pain. Others since have demonstrated similar results. So how does it work? What is the mechanism by which this hitherto unknown substance helps to relieve the symptoms of osteo and rheumatoid arthritis? Being a fatty acid ester, cetyl myristoleate possesses lubricant properties, and one of its properties is to supplement the synovial fluid that lubricates the joints and tendons. This helps to keep the joints moving freely, and reduces their tendency to grind when the connective tissue wears. It also lubricates entire muscle groups, allowing them to slide over each other more freely, and also over bones allowing a smoother movement of the joints. The second way, in which it operates, by supporting the immune system, is particularly appropriate to the treatment of rheumatoid arthritis which is caused by the immune system attacking the body’s own joint and connective tissue. In this respect, cetyl myristoleate has also been found effective in treating other immune system conditions such as multiple sclerosis and lupus erythematosus. Finally, it also possesses the mediation effect on the inflammatory reaction possessed by other essential fatty acids. This helps to reduce the effect of inflammation that causes much of the swelling and pain of arthritic conditions, although it occurs much faster than with other fatty acids. When taken together, all of these effects have a powerful effect in reducing the unpleasant symptoms of both osteoarthritis and rheumatoid arthritis. Swelling is reduced, mobility is improved and pain is alleviated. Improvements have been reported by sufferers of both types of arthritis, and in fact it is reported that Harry Diehl successfully treated his own arthritis with the substance before any other human tests had been carried out. Cetyl Myristoleate is now used word-wide in significant quantities, and there have as yet been no confirmed reports of adverse side effects. However, as with many otherwise safe supplements, it is recommended not to be taken by pregnant or lactating women until it has been proved to definitely have no side effects on the fetus or young babies. Although there is no definitive scientific evidence of the effectiveness of the substance in relieving the symptoms of arthritis, there is an overwhelming body of evidence from those that have used it world wide. The accepted treatment is by non-steroidal anti-inflammatory drugs (NSAIDs), and with over 16,0000 NSAID-related deaths in the USA alone each year, cetyl myristoleate is certainly worth considering as an alternative for arthritis sufferers. Not only that but there is a very significant price differential, with NSAIDs costing 5 – 10 times that of cetyl myristoleate. Among the other benefits that people using the substance have reported are beneficial effects on psoriasis, hepatitis, high blood pressure, eczema, allergies, headaches and many more. Although many of these might be coincidence or psychosomatic, it cannot just be coincidence that many of them, such as psoriasis and allergies, are related to the immune system. However, anybody with asthma or a history of severe allergic reactions should consult their physician before using the substance. That aside, there is more than enough popular evidence to indicate that cetyl myristoleate is effective in the treatment of arthritis in all its forms, and also good for your general state of health and wellness.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1785) Shark Cartilage
Date:
April 30, 2008 03:03 PM
Sharks do not have skeleton of bone but of cartilage, which is a dense form of connective tissue. Its main components are cells known as chondrocytes that are responsible for producing collagen fibers, an elastic protein called elastin that is responsible for the skin returning to its original shape after being pinched, and ground substance that is rich in proteoglycan, a protein with glycosaminoglycan chains. Shark cartilage is said to be beneficial in the treatment of many conditions including arthritis, psoriasis (allied to arthritis), rheumatism, eczema, acne, allergies and the most controversial – cancer. It is said to inhibit tumor growth by inhibiting angiogenesis – the formation of new blood vessels by growing them from old ones. This can lead to metastasis, or the spread of cancer between organs and also feed the cancer cells with blood. Shark cartilage has been used medicinally for thousands of years, particularly in ancient China where its use is documented, and might also have been in other areas where the consumption of fish was high. However, the production of shark cartilage and its trade is not well documented. The major cartilage consuming countries are Australia, India, Japan and the USA, although it is used or consumed in many other countries, especially Hong Kong, Taiwan, China and, increasingly, Europe. The best quality of cartilage is from the blue shark due to its higher chondroitin quality. Chemically, chondroitin is an acid mucopolysaccharide, and a very large molecule that is used for a variety of purposes. In arthritis it is difficult to get it to the source of the problem due to its physical size and large doses are used to ensure that at least a proportion passes through the capillaries to the joints. Arthritis is a particularly prevalent disease and comes in two forms: osteo- and rheumatoid arthritis. Osteoarthritis develops over a long period of time, and generally the cartilage roughens and becomes thin, while the bone becomes thinner. Extra synovial fluid, that lubricates the joint, can be formed and that causes swelling. The bone tried to repair itself, but degeneration continues and the tendons become affected. Eventually inflammation can occur leading to severe swelling and pain. There are several causes, the most common being injury or repetitive hard use of the joints. Rheumatoid arthritis, on the other hand, is completely different, and is caused by the immune system rather than wear and tear. The immune system mistakes parts of your joints as being foreign, and attacks the synovial membrane, or lining of the joint. It might also attack the sheath around the tendons. This eventually causes the cartilage to thin and the joints to wear, and the inflammatory response can cause painful inflammations. There is no apparent cause, though heredity, lifestyle and hormones might all be connected. The effect of shark cartilage on arthritis is well documented, and in one study in the 1970s, only 11% of patients did not respond well to a treatment of cartilage injections. The pain relief the injections provided lasted from six weeks to over a year, though no reason could be provided for the vast difference. However, it did seem to demonstrate that the remedy was more than just a placebo. In another study involving bedridden osteoarthritis patients, eight out of ten could leave their beds after only three weeks of oral cartilage treatment. Shark cartilage appears to be effective when administered both intravenously and orally. In a later placebo study involving 147 arthritis patients, they were given either shark cartilage or a placebo. Those with the placebo were encouraged to use other treatments when their pain became severe. After five years the placebo group reported a 5% drop in pain scores compared to 85% of the group taking shark cartilage. The joint deterioration in each group was assessed, and was considerably less in the cartilage group, who also lost less time at work through pain. All of these results indicate that shark cartilage can be used to relieve osteo- and rheumatoid arthritis pain in at least 60% of sufferers. Since rheumatoid arthritis has been linked to psoriasis, this could also explain its effects on psoriasis. What the studies did indicate is that you need not wait five years to find if the treatment is effective or not: if you do not experience positive results within between four and six weeks, then shark cartilage treatment will likely not work for you. There is no doubt that shark cartilage can provide relief to painful, swollen joints, and this is likely due to the mucopolysaccharides. It can also prevent the undesirable growth of new blood vessels into the cartilage and appears to help to regulate the immune system. These are also two of the reasons why it is believed by some to be an effective treatment for cancer by preventing metastasis. It was the publication of the book “Sharks Don’t get Cancer” that started the rush for shark cartilage as a a treatment for cancer, but the problem is that sharks do get cancer – they even get cancer of the cartilage! However, that does not mean that the scientific reasons for the inhibition of metastsis are invalid. They are valid, and it is metastsis rather than the original cancer that ferquently leads to death. Metastsis is the spread of the disease round the body by the bloodstream, and shark cartilage appears to be able to help to prevent that. It also prevents the growth of blood cells into cancerous areas to feed the cancers with oxygen and other nutrients. Although there are few reported side effects of shark cartilage, in the interest of safety it is advised that children and pregnant women should avoid it. The same is true of people recovering from recent surgery since it could slow healing due to its effect on repairing blood vessels. If you have a low white blood cell count, do not have a shark cartilage enema since it can cause a potentially fatal infection.
Otherwise it should be safe to take, and is available in many forms including creams, capsules, powders and injections. The recommended dosage is 1 gram dried shark cartilage for each 7 Kg (15 lb) body weight. Once you begin to see an effect on the pain of your arthritis, one can then try to reduce the dose to 1 gram for each 18 Kg (40 lb) body weight.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1778) Cherry Fruit Extract
Date:
April 28, 2008 02:45 PM
Cherry fruit extract contains organic compounds known as flavanoids, which is a form of phytochemical frequently found in highly colored fruits and vegetables. If you eat a fruit such as pomegranate, blueberry, blackberry or cherry, or if you eat red peppers, aubergines and broccoli, you are eating foods that are rich in flavanoids. Such foods provide you with remarkable health benefits that your ancestors knew about but did not understand. They ate these highly colored foods because they knew they helped prevent certain medical conditions, and to help others get well faster. They knew nothing about phytochemicals – chemicals contained in plants – or flavanoids, but knew about the results of eating them. In fact, flavanoids are very powerful antioxidants and anti-inflammatories, and each of these require more detailed explanation since between them, oxidants and inflammation are responsible for most of the non-infectious common ailments of the human body. First, let’s have a look at antioxidants. In chemical terms oxidation is the removal of an electron from an atom or molecule. There are species within your body known as free radicals whose sole purpose in their short life is to steal an electron from the nearest molecule to them. This is almost instantaneous, and most free radicals are very short lived. The concept of free radicals roaming your body and your bloodstream waiting to pounce on the first unwary molecule is a fairy tale. In fact the vast majority react as soon as they are formed. When they do react, they remove an electron from a stable molecule, render it unstable and thus destroy it. If that molecule is part of a cell, and enough of them are robbed of their electrons, then the cell is destroyed. One result in visible terms is wrinkling of your skin, as your skin cells become destroyed, and hence you age quicker. In terms that you are not immediately aware of, oxidation can lead to many unwanted changes in your body. For example, the low density lipids, that carry the cholesterol in your blood to areas of the body where it is needed, are oxidized by free radicals which causes the LDL to deposit along with their cholesterol on the walls of your arteries as a layer of plaque. Eventually that will build up to constrict the artery and cause a condition known as atherosclerosis – the arteries become blocked, and you can suffer from heart attacks and strokes. These free radicals are formed by the normal metabolism of the body when energy is created in the cell mitochondria, by pollutants such as pesticides, cigarette smoke and traffic fumes, and by radiation such as excessive exposure to the UV radiation in sunlight. Flavanoids, contained in cherry fruit extract, are antioxidants, which prevent this oxidation of body cells from taking place. They do so by being in the right place at the right time. If a flavanoid molecule is close to a free radical when it is generated, then the antioxidant will reduce the free radical and neutralize it. If you eat a lot of cherries, or drink cherry fruit extract, you will be consuming a massive amount of flavanoids molecules that are ready and willing to destroy these free radicals. However, that is not all that flavanoids do. They are also, as has already been stated, anti-inflammatories. The inflammatory response is the reaction of the body to a foreign presence such as bacteria. The tissues around the infected area receive an increased blood supply, and the cell walls produce gaps allowing the large immune system blood cells, or macrophages, to pass through. The temperature around the area increases due to the concentration of blood, and this itself is controlled by the body since bacteria die off after a certain body temperature has been reached, hence the reason for fever in the immune response. The area swells up due to the concentration of fluid and protein, and becomes painful due to pressure on nerve endings. Anti-inflammatories, such as the flavanoids, work to relieve the symptoms of inflammation without interfering with the way the immune system deals with infection. Many inflammatory conditions occur without any apparent reason, and while anti-inflammatories might not be used to suppress the immune system, it is used in such conditions as rheumatoid arthritis where the inflammation is a mis-firing of the immune system. Cherry fruit extract can be used to alleviate many similar conditions such as gout, and osteoarthritis where its use is well known and recorded. It can also be used to help reduce the effects of atherosclerosis through its anti-oxidant properties, and cherries contain, not only a good supply of flavanoids, but also anthocyanins, another group of powerful antioxidants. They also contain vitamin C which is also a strong antioxidant. Another property of flavanoids is their collagen strengthening properties, which they achieve by cross-linking the fibers to form a string fibrous network. That can be used to strengthen the walls of veins, and render them less liable to stretch or expand, thus providing them with the rigidity needed to prevent varicose veins caused by the puddling of blood below weak valves. They have the same effect on arteries, providing increased strength and a reduction in the blood pressure needed to pump blood round the body. A good intake of cherry fruit in your diet will help to improve the condition of your cartilage and other connective tissue in addition to your veins and arteries, and is particularly appropriate for athletes who place great stresses on connective tissues such as the tendons that transfer muscular energy to the levers – the long bones. In summary, then, cherry fruit extract and the flavanoids and anthocyanins it contains, posses properties to help relieve the symptoms of gout, and various forms of arthritis, to reduce the likelihood of cholesterol oxidation that leads to heart disease and strokes, to help strengthen the walls of veins and arteries and to improve the strength of connective tissue such as cartilage and tendons.
In other words, to improve the quality of life of the majority of the population that suffers from one or more of these conditions. After learning about the health benefits of cherries and all the mounting evidence in research, my question to you is why did the FDA make cherry farmers pull the health benefits of cherries from their websites with threats of legal action if not removed? Makes a person wonder who is on our side and who isn’t?
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1775) Bilberry Extract Is A Powerful Antioxidant That Strengthens Veins
Date:
April 12, 2008 11:06 AM
Bilberry extract is taken from the Vaccinium myrtillus, or bilberry, a small blue berry that has been used traditionally for the treatment of conditions now known to be due to inflammation and the action of free radicals on the body. Among these is atherosclerosis, or hardening of the arteries, caused by the free radical oxidation of the low density lipids that carry cholesterol around the bloodstream, and that cause deposition of fatty plaques on the arterial walls and eventually constricts them to a stage that can cause heart failure or a stroke, depending on whether the arteries are close to the heart or in the brain. However, additional to treating this condition, bilberry has also traditionally been used for the treatment of varicose veins and also for certain eye conditions. In fact it was during the Second World war that the Royal Air Force in Britain received reports from pilots that their night vision improved after eating bilberries. Not only their vision, but the restoration of night vision after exposure to glare. This was extremely important to war-time pilots who had to be able to rapidly adapt their vision to fly their plane after exposure to searchlights and explosive detonations. That is the reason for anything that appeared to promote this essential adaptation to be reported. The pharmacology of these effects have been found to be due to the anthocyanosides in which bilberries are particularly rich. Anthocyanosides consist of an anthocyanaidin backbone, to which one of either arabinose, galactose or glucose can be bound. Since bilberry contains five of these anthocyanadins, then there are fifteen different anthocyanosides in the fruit concentrate. The area of the retina that appears to control night vision, and the transition from day to night sight, is called the epithelium which is connected with purple vision. Anthocyanosides seem to have an affinity for this part of the retina, and in so doing plays an important part in this type of vision, specifically night vision although it is also beneficial in improving day vision. Although bilberry also contains vitamins A and C, hydroquinone and tannins, it is the anthocyanosides that provide it with its unique antioxidant properties, and also its effect upon collagen fibers. It can cross-link collagen fibers to help overcome weaknesses in the connective tissues such as cartilage, tendons and the walls of blood vessels. Its effect as an antioxidant is to prevent the cleavage of collagen by the cyzymes that are secreted by leukocytes generated by the immune system. By preventing histamine release, and release of prostaglandins and other proteins and cells mobilized during the immune inflammatory response to the detection of foreign invasion into human tissue, anthocyanosides can help to reduce inflammation and to protect against other extreme reactions of the immune system that can harm the organism it evolved to protect. The most powerful property of anthocyanosides are their antioxidant properties: perhaps even its only property once all of the conditions it helps to protect against are fully understood. An antioxidant combines with free radicals and destroys them. Free radicals are particularly vile chemical entities that require an electron to make them stable, and they take this electron from the nearest source. This can result in oxidation and destruction of many bodily tissues leading to premature aging, atherosclerosis, eye damage and many other problems that result from the destruction of body cells and tissue. The various constituents that make up bilberry act in concert to scavenge the free radicals and increase the supply of oxygen to the eye. The benefits of this are in helping to prevent cataracts and glaucoma, the latter due to the effect of the anthocyanoside cross-linking effect on the structure of the collagen in the eye. It can also help in cases of macular degeneration that affects the central area of the retina which might be due to the same property of there glucoside. Moving away from the eyes and back to the vascular system, the collagen cross-linking properties of the flavonoids, which is what anthocyanosides basically are, can help to repair damaged vein tissue by strengthening the vein walls themselves, and also by providing support for the cell membranes, or outer layers of the cells. This in turn builds up more strength in the vein tissue below the outside walls and contributes to an overall reduction in the weakness of the vein. This in turn enables it better to withstand the internal pressure put upon it by the failure of the valve that created the problem. In this way bilberries can be used to help repair the damage done by varicose veins and improve the function of the vein in returning blood to the heart from the extremities of the legs and also to help reduce the pain and swelling of varicose veins. In addition to these beneficial effects on the vascular system and the eyes, bilberry can also help to decrease the permeability of the blood-brain barrier to pollutants, drugs and other undesirable chemicals by improving the resistance of the capillaries in the brain to the transfer of such substances through their walls. It does so by preventing the collagen of the capillaries in the brain being degraded either by enzymes or other agents, Also, by helping to strengthen that collagen structure so that it becomes more impermeable to the larger molecules that form the pollutants. A lesser known constituent of bilberry is myrtillin, an anthocyanoside monoglucoside that is also available in all green plants, that possesses anti-glycemic properties. What this means is that it can reduce hyperglycemia and glycosurea, and so reduce blood sugar without reducing the blood sugar level to dangerously low levels. In other words it is an ideal insulin substitute. Native Americans used green plants for teas for centuries and were free from diabetes until the came into contact with Europeans and adopted their dietary habits. Although the case has to be proved, it appears highly likely that it was the myrtillin that kept them free from a condition that affects so many other races. Irrespective of that, however, it is for its powerful antioxidant effect that bilberry finds its best use, and also its effects on varicose veins. However, all of the above health benefits that bilberry provides, can likely be laid at the door of the combined antioxidant effect of its vitamin C content and the anthocyanosides – including the glucoside myrtillin.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1753) The Benefits of Ascorbyl Palmitate A Fat-Soluble Form of Ascorbic Acid
Date:
February 09, 2008 10:43 AM
The benefits of ascorbyl palmitate are due to the substance being a fat-soluble form of ascorbic acid which is otherwise known as vitamin C. Before discussing why being fat-soluble should be of benefit, let us first have a look at what vitamin C does for us and what its limitations are. Most people know vitamin C as the vitamin that prevents us from getting scurvy, and that limes and other citrus fruits were given to sailors to prevent them from contracting this often fatal disease on long journeys. However, important though the protection it provides against scurvy is, there are many more important uses for this important vitamin. In fact some of them are closely connected to the symptoms of scurvy. Among these are pains and swelling in the joints, and the loosening of teeth and hair loss. Scurvy is also associated with easy bruising and bleeding. All of these can be associated with loss of collagen, which is contained in connective tissues, bone and blood vessels. Collagen repairs and maintains cartilage, heals wounds and is essential for proper skin formation and the structure of ligaments, tendons, blood vessels, bones, hair and teeth. When we consider that one of the most important properties of vitamin C is the part it plays in the production of collagen in the body, then its effectiveness in alleviating the symptoms of scurvy is not difficult to understand. Vitamin C is also a strong antioxidant that destroys free radicals that kill and severely damage body cells, and cause a large variety of undesirable conditions such as atherosclerosis and cancers, and also debilitating and painful inflammatory conditions such as arthritis. Many free radicals are formed in the body as by-products of our metabolism: the generation of energy from fats and blood glucose. Others are ingested in the form of cigarette smoke and other toxins, while yet other free radicals are caused by the effect of sunlight on our skins. Natural antioxidants such as vitamins A, C and E help to keep these free radicals under control and minimize their effect. Another interesting property of vitamin C is in the synthesis of carnetine, a deficiency of which is also thought to contribute to scurvy. Carnetine is needed by the body to transport fat to the cellular mitochondria so that it can be converted to energy. Vitamin C is also believed to take part in the biochemistry that converts cholesterol to bile acids and so helps to maintain a healthy level of cholesterol in the blood. The vitamin is therefore a very useful one for the body, but it has one fault. It is water soluble, and hence cannot be stored in the body but is expelled in the urine. Had it been fat soluble it could have been able to be stored in the body fats, in the same way that vitamins A and E are, and be available for use when required. Instead any excess that is not immediately used is lost, and a fresh intake of ascorbic acid necessary on a continuous basis. Not only that, but it is only of use in areas of the body that the blood can reach. Fatty tissue is practically devoid of vitamin C, and many areas of the brain cannot be reached by substances that are insoluble in oils and fats. It also finds it difficult to penetrate the skin and the walls of body cells. This is where the benefits of ascorbyl palmitate are useful. Ascorbyl palmitate is a fat-soluble form of vitamin C and possesses all of the attributes of ascorbic acid. It is more easily absorbed by the body and can be stored in the membranes of the cells until needed. It is also a powerful antioxidant, the same as vitamin C, and is frequently used to prevent the oxidation of vegetables oils, such as on potato chips and other oily snacks. It also takes part in the biochemistry of the production of collagen and connective tissues. The usefulness of this substance comes from not only from its amphoteric nature, whereby it has one end that is water soluble and another that is fat soluble, but also by the fact that it is also amphipathic, meaning that it prefers neither one medium nor the other, and tends to collect at phase boundaries, between oil and water phases. It is particularly effective in topical uses on the skin, because it is easily absorbed into the skin tissue, and more stable than some of the other forms of vitamin C. It is also believed to protect other fat soluble antioxidants such as vitamin E from oxidation, and also to help to protect blood cell membranes from free radical attack. Although vitamin C is a very powerful vitamin, carrying out a multitude of tasks, ascorbyl palmitate has some advantages over it apart from the solubility difference. Its antioxidant properties are stronger than those of regular ascorbic acid and in fact rival those even of vitamin E, which it also helps to regenerate after its reaction with free radicals, and help to maintain a continuous supply of this powerful antioxidant. It is also a chemically neutral form of the vitamin, and unlike regular ascorbic acid, does not cause inflammation of the tissues it comes into contact with. It can also reduce sunburn due to excessive exposure to UVB when applied to the skin, and is a very stable form of the vitamin. Ascorbyl palmitate also acts as an anti-inflammatory with certain conditions, such as psoriasis where topical application helped to reduce the extent of the lesions. In fact it appears to do most of what vitamin C does, but faster and with smaller doses. So why is ascorbyl palmitate not used as the main form of vitamin C in supplements? The answer is money. Ascorbyl palmitate is considerably more expensive than regular vitamin C, and also normal ascorbic acid has some properties that the fat-soluble form does not have, such as its ability to rapidly pass through the body in the bloodstream. However, it would make sense to take a supplement consisting of both forms of vitamin C, and so combine the best properties of each. Any vitamin C supplement that is designed for maximum effect on the body should contain at least 25% of ascorbyl palmitate, the balance being ascorbic acid. That is what to look for if you are to receive the combined benefits of both water and fat soluble vitamin C.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1715) Support Healthy Joint Function With Discount Vitamins
Date:
November 22, 2007 11:05 AM
The joints are very important to your mobility and it is essential that you support health joint function with discount vitamins. The reason for discounted vitamins is that there is no need for you to pay more than you have to, and good healthy bones and joints need a good supply of several vitamins, minerals and other substances to remain healthy throughout your lifetime. Vitamins C and D, and calcium and magnesium are the more common supplements that help to promote joint health, but glucosamine, chondroitin and gelatine also play a large part. Although the strength of the bone is important, it is disorders of the connective tissue that are mostly responsible for joint problems. Connective tissue holds the joint together and prevents excessive friction between bones. Arthritis in both its forms – osteoarthritis and rheumatoid arthritis – is characterized by a reduction in the cartilage tissue that provides a lining between the bones that make up the joint. As the cartilage becomes worn or its structure destroyed, the bones are exposed to each other and this causes the frictional damage that is osteoarthritis. With rheumatoid arthritis, on the other hand, the connective tissue and cartilage are attacked by the body’s immune system, causing inflammation. The reason for this is still unknown, but the inflammation leads to swelling of the joint and severe pain. Both of these conditions can be helped by the use of glucosamine, a natural substance produced by the body to form cartilage and stimulate the formation of connective tissue. Normally taken in the form of the sulfate, glucosamine reduces arthritic pain, and over time can start to rebuild the lost cartilage. It is best taken in conjunction with chondroitin sulfate which is a substance also contained in cartilage and connective tissue. A discount vitamin supplement containing glucosamine and chondroitin can help to avoid these conditions from occurring. Rheumatoid arthritis also responds well to anti-inflammatories and antioxidants. Much of the damage to the joint tissues can be caused by the action of free radicals that are aggressively destructive molecules created by the effects of pollution such as smoking, pesticides, heavy metals, alcohol and they are also produced by many of the processes occurring inside our bodies. The immune system itself creates free radicals to use as a weapon against invaders. A free radical is a molecule that has lost an electron, especially an oxygenated molecule. The objective of such a molecule is to get back its electron, and it will do that by oxidizing any molecules it comes across: oxidation is the removal of an electron from a substance. Oxidation can destroy cell molecules which is why the aging process occurs through the destruction of body cells through the effect of oxidation by free radicals. They can also destroy the synovial fluid that lubricates the joints. The molecules that can prevent this are caused antioxidants, and include some of the well known vitamins such as A, C and E, and also other substances such as Coenzyme Q10, fatty acids such as those in Omega 3 fish oils, beta carotene and the minerals zinc and copper are also effective at reducing the inflammation cause by free radical oxidation. These vitamins and minerals will not reduce the pain in your joints, but will relieve other symptoms such as the inflammation, and help the joint to recover. Vitamin D is another that can help to cause arthritis and joint problems if you are deficient in it. Vitamin D deficiency is not uncommon, especially in those who live in northern climates where they do not get much sunlight. This vitamin helps to build cartilage and to maintain healthy bone density. Vitamin D is found in oily fish and eggs, but the majority of people suffer a deficiency, if only slight in many cases. Discount vitamin supplements containing all of these vitamins and minerals will help to maintain healthy joints. Vitamin A is available naturally from eggs yolks, oily fish and dairy products, and most people know that vitamin C is obtained from fresh fruit and vegetables, especially the highly colored foods that are also rich in other antioxidants such as anthocyanins and carotenoids. Rich sources of vitamin E include nuts, seeds, vegetable oils and wheat germ. Taking Omega 3 oil supplements will not prevent arthritis, but will help to relieve the inflammation and hence the pain. However, in spite of all of this, the only vitamin that has been extensively tested on patients suffering from osteoarthritis has been vitamin E. It has been established that significant improvements in the condition of patients were achieved by administering from 400-600 International Units (I.U.) of vitamin E daily for two weeks. Another substance that is a component of connective tissue and that can be taken to help rebuild what is lost in joint disease is hyaluronic acid. This chemical is found all over the body, and involved in the structure of many types of connective tissue, including the joints, the vitreous humor of the eyes and heart valves. In the joints it is rich in the synovial fluid that lubricates the joints, and also found in cartilage. Although hyaluronic acid is contained in chicken soup, it is obtained mainly from rooster combs, then treated to reduce its molecular size so that it can be absorbed. Anybody allergic to chicken should seek their doctor’s advice on taking hyaluronic acid as a supplement. It is highly recommended that a vitamin supplement be taken by anybody suffering from any form of arthritis or joint disease, but it is glucosamine that appears the best treatment for long term success. Glucosamine is a very large molecule, and it is difficult to get it to the site of the problem. To get to the joint, the molecule has to pass through the capillaries, and very few glucosamine molecules can actually achieve that. That is why the doses are so large, so that even if only a small percentage gets to the joint then that is enough to help rebuild cartilage. The antioxidants help to destroy the root cause of many forms of joint disease: the free radicals and anti-inflammatories can help relieve pain. However glucosamine and chondroitin not only relieve the pain, but also continue to work over time to repair the joint tissues. As with most supplements the body can only absorb so much glucosamine, only consume 500mg at a time but take it two to three times each day for best results. Glucosamine is often provided in conjunction with MSM (Methylsulfonylmethane) that is a natural form of dietary sulfur. Sulfur is believed to be essential for healthy soft connective tissues, tendons and so on. Calcium, too, is a useful supplement to take since it help to recover the bone density, but keep in mind that vitamin D is essential for the uptake of calcium, so a vitamin D supplement will be required along with the calcium. Although calcium will not in itself help joint disease, it will help to main a good bone density that is more capable of withstanding the stresses of a reducing cartilage density. There is therefore quite a wide variety of vitamins, minerals and other substances that can help to support healthy joint function, and also to help repair joint damage, and discount vitamins are the best way to tackle the problem of maintaining a good intake of those that are most effective, namely, glucosamine and chondroitin sulfate, vitamins A, C, D and E, and supplemental MSM, hyaluronic acid and calcium. You do not need them all, but only testing will enable you to decide which work for you. You should also contact your physician before taking discount vitamin supplements if you have any other medical problems.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1638) Glucosamine Sulfate and Chondroitin Sulfate
Date:
March 28, 2007 11:10 AM
Glucosamine Sulfate and Chondroitin Sulfate Osteoarthritis is the most prevalent form of arthritis in the U.S., according to the Arthritis Foundation. One-third of all American adults have X-ray evidence of osteoarthritis of the hand, foot, knee, or hip. Osteoarthritis is responsible for more than 7 million physician visits per year and is second only to cardiovascular disease as the cause of chronic disability in adults. As Baby Boomers age, the number of people suffering from osteoarthritis is expected to rapidly increase in the next 10 years. While osteoarthritis research ahs led to the development of promising new prescription and over-the-counter medications aimed at reducing pain, none has created the excitement of glucosamine sulfate (GS), which actually addresses the underlying joint destruction. Q. What is osteoarthritis? A. Osteoarthritis is a complex, metabolic disorder of the cartilage and bones of certain joints. However, to fully understand how osteoarthritis develops, we need to understand how joints work. A joint is formed when two or more bones are brought together and held in place by muscles and tendons. Some joints have very little range of movement, such as the joints of the ribs, while others have much more range of movement. Hips, knees, elbows, writs, and thumbs are termed synovial joints, and have the greatest range of movement and mobility of human joints. To allow such mobility, synovial joints have a unique structure. The bones that form synovial joints are covered with cartilage. Tough fibrous tissue encloses the area between the bone ends and is called the joint capsule. The joint cavity within the capsule is lined with an inner membrane, called synovial membrane. The membrane secretes synovial fluid, a thick, slippery fluid that fills the small space around and between the two bones. This fluid contains many substances that lubricate the joint and ease movement. The cartilage of synovial joints serves two very important functions. First, it provides a remarkably smooth weight-bearing surface; synovial joints move easily. Secondly, synovial cartilage serves as a shock absorber, providing a soft, flexible foundation. Healthy cartilage absorbs the force of the energy, transmits the load to the bone, and distributes the mechanical stress created by joint movement. Synovial joints function under almost continual mechanical stress. A joint’s ability to withstand or resist this stress is a reflection of its health. When the mechanical stress is too great or the joint’s ability to resist this stress is compromised, physical changes occur in the cartilage covering the bones. Cartilage is a tough, elastic tissue, comprised mostly of water, collagen, and complex proteins called proteoglycans. In osteoarthritis, the cartilage starts to weaken, becomes frayed, and eventually breaks down. This exposes the bones of the joint, which then rub together. A gritty feeling and grinding sound may occur when an osteoarthritic joint is bent and flexed. As osteoarthritis progresses, bits of bone and cartilage often break off and float inside the joint space. The bones may enlarge, causing the joint to lose its normal shape. Tiny bone spurs may grow on the joints’ sides and edges. These physical changes in the diseased joint are responsible for progressive damage and continual pain. People with osteoarthritis most frequently describe their pain as deep and aching. The pain not only is felt in the affected joint but may also be present in the surrounding and supporting muscles. Joint inflammation also may occur, increasing the already considerable discomfort. Joint stiffness is another unfortunate component of osteoarthritis. Exercising the joint most often results in increased pain; however, stiffness tends to follow periods of inactivity. Humid weather often makes all osteoarthritis symptoms worse. As the disease progresses, the pain may occur even when the joint is at rest, creating sleepless nights and miserable days. Q. What causes osteoarthritis? A. Osteoarthritis’ exact cause remains unknown. Researchers know aging doesn’t appear to cause osteoarthritis. Cartilage in people with the disease show many destructive changes not seen in older persons without the disease. However, certain conditions do seem to trigger osteoarthritis or make it worse. Some families seem to have a lot of osteoarthritis, pointing to a genetic factor. This is most commonly seen in people who have osteoarthritis of the hands. Repeated trauma can contribute to osteoarthritis, too. Athletes, extremely active people, and individuals who have physically demanding jobs often develop the disease. Persons who have certain bone disorders are more prone to osteoarthritis due to the continuous, uneven stress in their hips and knees. Obesity also is a risk factor for the disease. In overweight women, osteoarthritis of the knee is fairly common. Excess pounds also may have a direct metabolic effect on cartilage beyond the effects of increased joint stress. Obese people also often have m ore dense bones. Research has shown dense bones may provide less shock-absorbing function than thinner bones, allowing more direct trauma to the cartilage. Q. Can osteoarthritis be prevented? A. While there is currently no sure way to prevent osteoarthritis or slow its progression, some lifestyle changes may reduce or delay symptoms. The Arthritis Foundation states that maintaining a healthy weight, losing weight if needed, and regular exercise are effective osteoarthritis prevention measures. Optimal calcium intake in younger years is vital to ensure a healthy aging skeletal system. Vitamins A, C, D, and E have been studied for their role in osteoarthritis prevention. These vitamins also have shown benefit in individuals who have osteoarthritis. Q. What treatments are available for osteoarthritis? A. The goal of treatment is to reduce or relieve pain, maintain or improve movement, and minimize any potential permanent disability. Typically, non-steroidal anti-inflammatory drugs or NSAIDs (pronounced “n-sayds”) such as aspirin and ibuprofen are used for pain and inflammation relief. These medications are effective in treating only the pain of osteoarthritis. These medications have many side effects, some of which are serious. NSAID-induced gastrointestinal complications cause more than 100,000 hospitalizations and nearly 16,500 deaths annually in the U.S. Aspirin can cause an extremely annoying and continual ringing in the ears. NSAIDs frequently cause damage to the stomach lining, which can produce uncomfortable heartburn and abdominal pain. Continued NSAID use may lead to the development of stomach ulcers. NSAID-related ulcers can perforate the stomach lining and cause life-threatening bleeding. Most NSAIDs also interfere with blood clotting and may cause kidney damage. When older persons take NSAIDs, dizziness, drowsiness, memory loss, and decreased attention span may occur. Acetaminophen (Tylenol and similar medications) is similar to aspirin and other NSAIDs in its pain-relief abilities. However, acetaminophen doesn’t reduce inflammation. And while acetaminophen doesn’t have the same side effects of aspirin and other NSAIDs, if large doses are taken, liver damage can occur. Newer medications called COX-2 inhibitors provide both pain relief and reduce inflammation without the many side effects of acetaminophen, aspirin, and other NSAIDs. More recent research has indicated that, in certain situations. COX02 inhibitors also can cause stomach lining damage and bleeding. While aspirin, NSAIDs, and COX-2 inhibitors may reduce osteoarthritis pain, they do nothing to stop or slow down cartilage deterioration. In other words, these medications have no effect on the disease itself. That is why many believe glucosamine sulfate (GS) and chondroitin sulfate (CS) are preferable to pain relievers and anti-inflammatory medications in osteoarthritis treatment: they actually improve synovial joint health. And they do this without potentially life-threatening side effects. Q. How do GS and CS work? A. GS improves the health of joints affected by osteoarthritis. This supplement is so effective that even physicians who mostly rely on conventional medications routinely recommend it to their patients with osteoarthritis. In fact, GS is so good at treating osteoarthritis, many physicians use it for their own osteoarthritis joints. There is even more good news. When glucosamine sulfate is combined with low-molecular weight CS, even greater benefits can be achieved. GS and CS are naturally occurring compounds found in human joints. The right GS/CS combination actually reverses damage in joints affected by osteoarthritis, in turn significantly reducing pain and stiffness. Glucosamine occurs naturally in the body and is found in synovial fluid. Glucosamine is a basic building block for proteoglycans, is a basic building block for proteoglycans, one of the important compounds of synovial cartilage. It also is required for the formation of lubricants and protective agents for the joints. In Europe, GS and CS have been used to treat osteoarthritis for more than 10 years. While persons with arthritis felt much better when they took GS and CS, no one really knew how these compounds worked. When European and American researchers first started to study glucosamine, they discovered GS can reduce synovial joint inflammation. This explains why people felt better after taking it. Q. What has additional study of GS and CS revealed? A. As the scientific study of GS progressed, researchers determined it can stimulate the growth of cartilage cells, inhibit proteoglycans breakdown, and rebuild cartilage damaged from osteoarthritis. In other words, GS does not simply make persons with osteoarthritis feel better; GS actually makes persons with osteoarthritis get better. GS is the form of glucosamine used in research. It’s the sulfate salt of glucosamine and breaks down into glucosamine and sulfate ions in the body. The sulfate part of GS plays an important role in proteoglycans synthesis. CS also provides cartilage strength and resilience. CS is an important component of the cartilage proteoglycans of synovial joints. Because CS helps the production of proteoglycans, researchers believe CS works in a similar nature to GS. Q. Couldn’t GS and CS be taken on their own? Is there any benefit in taking them together? A. Research has discovered GS and CS act synergistically (work well together) in improving joint health. Several studies have investigated this action and it’s recommended that GS and CD be taken together. However, there may be times when your healthcare practitioner may recommend using one or the other, but not both GS and CS together. Please follow their recommendations to obtain the best results for your own unique health concerns. Low-molecular weight chondroitin sulfate (CS) is the preferred CS form, and the form that has shown the most promise in studies. Q. Why is it important to take low-molecular weight CS? A. When CS was first studied, it was given to six healthy volunteers, six patients with rheumatoid arthritis, and six patients with osteoarthritis. Researchers then measured the levels of CS in all study subjects. They found no evidence of CS in any of the subjects. This single study led many physicians and scientists to believe CS can’t be absorbed, and was not an effective natural treatment. However, several other studies in healthy volunteers have reported CS can be absorbed. The distinct difference for these findings is thought to be associated with the types of CS used in the studies. Some forms are much more absorbable that others. This was demonstrated in a recent study using CS with lower molecular weight. A higher absorption is observed for low-molecular weight CS. This means CS products with a low molecular weight may be better absorbed, allowing the CS to get into the bloodstream and the synovial fluid of joints where it’s needed. Q. Are there other supplements that can help osteoarthritis? A. Several vitamins, minerals, enzymes, and natural supplements have benefits for individuals with osteoarthritis. Proteolytic enzymes effectively offer relief of the pain, stiffness, and swelling of osteoarthritis. Folic acid and vitamin B can reduce the number of tender joints and increase joint mobility. Vitamins C, D, and E not only may prevent osteoarthritis, but inhibit the disease’s progression. Niacinamide improves joint function, range of motion, and muscle strength. Clinical studies using the herb Boswellia serrata have yielded good results in osteoarthritis. Application of ointments on osteoarthritic joints may be helpful in reducing pain and stiffness. Menthol-based preparations can provide soothing relief to painful joints. Capsaicin ointments and gel made for cayenne pepper also are very beneficial. When applied to the skin, capsaicin first stimulates, then blocks, nerve fibers that transmit pain messages. Capsaicin depletes nerve fibers of a neurotransmitter called substance P. This neurotransmitter transmits pain messages and activates inflammation in osteoarthritis. Capsaicin ointment is very effective in relieving osteoarthritis pain in many individuals. Q. Is there anything else I can do for joint pain and stiffness? A. When osteoarthritis occurs in the hands, use of a paraffin dip can be very comforting. A licensed health care practitioner can provide information about how to safely use paraffin dips at home. Exercise is an excellent way to keep joints mobile, decrease pain, and increase body strength, too. Water aerobics also can reduce the pressure and stress on joints. The Arthritis Foundation strongly suggests making movement an integral part of your life. When you’re in less pain and have more energy, more range-of-motion, and a better outlook on life, you’ll reduce stress and be a much healthier person despite your osteoarthritis. One important last thought When we don’t feel well, we sometimes have a tendency to self-diagnose. If you haven’t been evaluated by a licensed health care practitioner for your joint pain and stiffness, you need to do so. These symptoms may be caused by other illnesses and may require much different treatment. Only licensed health care practitioner can provide a certain diagnosis of osteoarthritis. Conclusion Osteoarthritis may be a part of life for many of us as we age; however, constant pain and stiffness need not be. GS combined with absorbable CS can actually improve damage in joints affected by osteoarthritis and significantly reduce pain and stiffness. And it can be an empowering way to improve your health. Buy Glucosamine and Chondroitin Sulfate at Vitanet ®, LLC
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1500) Degenerative joint disease (osteoarthritis)
Date:
August 24, 2006 03:55 PM
Degenerative joint disease (osteoarthritis) damages or destroys cartilage and its supportive collagen structure. As many as 40 million Americans, including the majority of people over age fifty, are thought to suffer from some form of this disease. Primary osteoarthritis, the “wear and tear” form, is due to normal use and age-related causes. Secondary osteoarthritis results from repeated joint trauma, inherited predisposition, or previous inflammatory conditions. While non-steroidal anti-inflammatory drugs (NSAIDs) treat symptoms only, a natural, holistic approach strives to improve the environment of the cartilage and joint as a whole by providing protective and restorative nourishment, increased circulation, decreased inflammation and reduced free radical damage. High levels of Glucosamine and Chondroitin Sulfate Widely regarded as the first defense in protecting joints, glucosamine and Chondroitin sulfate have been shown to effectively control joint pain and slow down or reverse the progression of cartilage deterioration. The integrity of joint gliding surfaces as well as the health of tendons, ligaments, joint fluids, skin, bones, heart valves and virtually all structural elements in the body is dependent upon the proper synthesis and availability of proteoglycans, integral components of joint cartilage. Glucosamine provides two components critical to the synthesis of proteoglycans: hyaluronic acid and glycosaminoglycans (GAGs). Chondroitin sulfate represents an important group of GAGs. It is not a single compound, but rather a class of compounds with different molecular weights that each have specialized functions within the body. Numerous studies have shown that long-term safety, reduction in pain and protection of cartilage with body chondroitin and glucosamine are comparable or superior to results obtained with NSAIDs. MSM. (Methylsulfonylmethane) MSM is a rich source of sulfur, a mineral required for GAG synthesis. A preliminary study suggests that MSM may help reduce pain in persons with degenerative arthritis. Gota Kola. (Centella asiatica) known to support collagen synthesis and stimulate GAG’s, Gota Kola has been used for many years in Europe to promote wound healing and blood vessel integrity. It also has been shown to improve circulation in small vessels. Turmeric. (Curcuma longa) this saffron-colored root offers a wide range of benefits. It naturally inhibits the inflammatory COX-2 enzyme, reduces pain and is a potent antioxidant that protects the liver and other cells. High antioxidant diets may inhibit joint deterioration. Bromelain. Derived from pineapple cores, Bromelain is most commonly used for healing soft tissue injuries and inflammation. It contains potent selective proteases (protein-digesting enzymes) and other substances which serve to block destruction of GAGs. Trace Minerals. Micronutrients play many distinct roles in support of healthy joint connective tissue and joint cartilage matrix. Black Pepper Extract. Bioperine is a highly concentrated extract (95% - 98% piperine) of black pepper. Used as a bioavailability enhancer, it has been shown to increase the absorption of vitamins, minerals and herbs.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1356) SAMe (S-Adenosylmethionine)
Date:
December 17, 2005 09:42 AM
Supports Healthy Nervous System and Joint Function Vital For Over 35 Biochemical Reactions Necessary For Optimum Health Promotes a Healthy Mood As the building blocks of protein, amino acids are vital to health. Next to water, amino acids in the form of proteins make up the greatest portion of our body weight. They comprise tendons, muscles and ligaments; organs and glands; hair and nails; important bodily fluids, and are a necessary part of every cell in the body. There are over 20 amino acids, separated into two categories – essential and non-essential. Essential amino acids are those that cannot be manufactured by your body, hence, it is essential that you obtain them from your diet. Non-essential amino acids can be manufactured by your body, however, your body must have the right combination of essential amino acids and supporting nutrients to optimize healthy protein maintenance, so supplementation may be desirable. Amino acids are not only absolutely integral to life, they can have a profound impact upon how clearly we think and how well we feel. SAMe (S-Adenosylmethionine) SAMe (S-adenosylmethionine) is a naturally occurring combination of the amino acid methionine and ATP (adenosine triphosphate), the body’s primary energy molecule. In this form it is sometimes referred to as “active methionine”. Research indicates that SAMe plays a vital role in nervous system health and normal cognitive function.* SAMe may support nervous system function by increasing the synthesis and recycling of certain neurotransmitters and enhancing the sensitivity of nerve receptors. SAMe is believed to positively affect a number of neurotransmitters, including serotonin, dopamine, noradrenaline and norepinephrine. Although the mechanism for SAMe’s impact upon neural function is not fully understood, there is no doubt that SAMe’s capacity as a methyl donor is of critical importance. As a methyl donor SAMe assists the body in the creation of complex organic compounds necessary for normal healthy function. Your body uses these new compounds for numerous purposes, including brain function and detoxification. This process, known as methylation or transmethylation, is vital to your body’s maintenance. SAMe may be the most effective of all methyl donors discovered to date. Research has shown that SAMe is the only methyl donor with the potential to increase transmethylation in the brain, which helps to protect it from homocysteine damage as well as increasing production of glutathione, one of the body’s most effective antioxidants. Research into the biosynthesis of SAMe has established a clear link between SAMe and folic acid, or folate. Folic Acid has been proven to provide support for healthy nervous system function and a healthy mood, and researchers believe these two nutrients work together to beneficially affect monoamine systems, which directly affect mood and cognitive function.* SAMe has also been shown to improve the synthesis of phospholipids for use in the brain, probably one of the most beneficial effects SAMe has on brain health. The benefits of SAMe extend beyond the brain and throughout the human body. For example, it may also aid in the repair of myelin, the sheath of fatty material that surrounds nerves and nerve cells everywhere in our nervous system. It’s found in all human tissue and organs and is available for use by your body in over 35 different biochemical reactions necessary for optimal health. SAMe may support joint health through transulfuration, a process that takes a certain amount of sulfur from SAMe to create glucosamine and chondroitin sulfates. This enhances proteoglycan synthesis, the molecule responsible for keeping articular (joint) cartilage lubricated. As mentioned earlier, SAMe is also important for the production of glutathione, a powerful free radical scavenger that defends your body from toxic agents and is necessary for liver detoxification. SAMe was first isolated in 1952 by G.L. Cantoni at the Laboratory of Cellular Pharmacology at the National Institutes of Health, Bethesda, Maryland. Four years later, Cantoni and a co-worker found that SAMe synthesis involves methionine and ATP. They also found that it exists in the human body only temporarily, making production in a supplemental form difficult. It took nearly ten years until improvements in technology permitted SAMe research to advance. With the discovery of a method to stabilize SAMe that overcame these manufacturing problems, U.S. patents were granted to allow the production of SAMe in a stabilized form. SAMe in its ion form, as found in human cells, has a very short life span and is rapidly metabolized into other necessary compounds as needed. Therefore, it must be manufactured in a stabilized form to prevent rapid degradation as a supplement. Once tableted, it must be enteric coated to preserve stability. This technology was not readily available until the 1990’s, hence SAMe’s long road to mainstream popularity. Dr. Joseph Zhou, Director of Laboratory Methods here at NOW, is credited with significantly improving the analytical methodology used to assure potency levels in supplemental SAMe. His work is one of the reasons SAMe is available as a supplemental with stable, guaranteed
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1019) PYCNOGENOL ® - The Ultimate Antioxidant
Date:
June 04, 2005 02:04 PM
Pycnogenol® is a breakthrough in antioxidant protection that demonstrates how important natural nutrition can be for your health. Antioxidants are a class of biological molecules that function to scavenge and neutralize free radicals. Free radicals are molecules with unpaired electrons that cause damage at the cellular level, and which unfortunately are unavoidable. Antioxidants – the most famous of which thus far have been Vitamin C and Vitamin E – work to protect living tissue by neutralizing free radicals, thereby interrupting many of their harmful activities. Pycnogenol®, one of the most powerful antioxidants yet discovered, is the proprietary name of a natural plant product made from the bark of the European coastal pine, Pinus maritima. It is 20 times more potent an antioxidant than Vitamin C, and 50 times more so than Vitamin E. Free radicals are a real threat Uniquely vulnerable targets of free radical attack that require a regular supply of antioxidants just to maintain a basic level of function include fatty acids – especially those in cell membranes – and sulfhydral proteins, which form one of the most common types of chemical bonds found in biological organisms. The importance of these substances for overall health cannot be overstated, as they are critical components not only of tissues throughout the body, but most importantly, of the principal regulatory organs – the brain and liver – and every blood vessel. Free radical attack on fatty acids – known as lipid peroxidation – and related destruction of sulfhydral proteins can lead to diminished function of cell membranes and whole organs. This, in turn, can contribute significantly to decreases in quality of life. Free radicals are believed to be active in the development of cumulative damage to the system, as well as in many of the undesirable effects of aging. Free radicals are constantly being produced due to the natural intake of oxygen and generation of energy by the body’s cells. However, their production is heightened by pollutants such as tobacco smoke, alcohol, solvents, and oxidized cholesterol from foods. Therefore, health scientists suggest we may need to increase our intake of antioxidants either from foods or from supplements – such as Vitamin A and Beta Carotene, Vitamins C and E, Selenium, Cysteine, and now, Pycnogenol®. Potent antioxidant protection from nature - Pycnogenol® Originally discovered by renowned scientist Jacques Masquelier, Pycnogenol® is a natural 85% to 95% concentrate of proanthocyanidins extracted from the bark of the Maritime Pine. Proanthocyanidins are a special class of highly bioavailable, water-soluble bioflavonoids with unparalleled free radical scavenging activity. They readily cross the Blood-Brain Barrier to provide antioxidant protection to the central nervous system, and stay in the bloodstream for approximately 72 hours. Thirty years of sound European research shows that proanthocyanidins from Pycnogenol® are highly beneficial with no evidence of adverse effects, even after more than ten years of use. They also show no loss in potency after 12 years of storage. Better health for an active life As a potent antioxidant, Pycnogenol® is valuable for protecting the liver from free radical attack. Since the liver is the main detoxifying, nutrient-assimilating, and energy-generating organ of the body, this may mean more potential for activity in your life. Pycnogenol® may also aid recovery for athletes on strenuous workout regimes and in competition. Healthy capillaries through healthy collagen A major beneficiary of the protective actions of Pycnogenol® is collagen, the most abundant protein in the body. Collagen is responsible for maintaining the integrity of “ground substance,” the basic material in functional fluids, mucus linings, and connective tissue such as tendons, ligaments, cartilage, and most importantly, blood vessels linings. It is highly vulnerable to free radical attack, and a number of discomforting and depreciating processes are associated with its destruction. There is evidence showing that Pycnogenol® can provide remarkable support for the prevention of collagen destruction, and it has received much attention for its special affinity for capillaries, the smallest blood vessels. Pycnogenol® helps strengthen capillary linings in three key ways. First, Pycnogenol® functions to scavenge the free radicals that may compromise the integrity of collagen. Second, Pycnogenol® contains catechin, which is thought to stabilize collagen by forming hydrogen bonds and cross-linking collagen. Third, Pycnogenol® is Vitamin C-sparing, meaning it can fill in for C in a number of functions; this frees some Vitamin C – required for the synthesis of hydroxproline, a major structural amino acid of collagen – for use in building collagen. People who smoke and women who take oral contraceptives can reduce their heightened risk of Vitamin C depletion by taking advantage of Pycnogenol®’s Vitamin C-sparing activity. Look to Source Naturals® for 25 mg, 50 mg, 75 mg, & 100 mg tablets of this natural wonder!
References
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=188) MSM - Methylsulfonylmethane: Nature’s Source for Dietary Sulfur
Date:
June 04, 2005 09:42 AM
Sulfur is an important component of our body’s proteins. It is present in our hair, skin, nails and tendons, and plays a critical role in maintaining the integrity and elasticity of connective tissue. And now this vital nutrient can be obtained from a natural, bioavailable source. MSM, or methylsulfonylmethane, is a naturally occurring form of organic sulfur. Though present in dietary sources such as milk, eggs, fish, fruits, vegetables, grains and lean meat, MSM may be lost as a result of over-processing and heating – a particular problem in the modern diet. That’s why Source Naturals created MSM. Taking MSM throughout the day helps to replenish the body’s supply of assimilable sulfur. Sulfur Helps Maintain the Integrity of Connective Tissue Sulfur is found in proteins throughout our bodies and is vital to our connective tissues. It must be present in the body in correct balance to keep our tissues elastic and free. Sulfur in our bodies is a major constituent of the glycosaminoglycans, or GAGs. These large, spongy, waterholding molecules are long chains of amino sugars, including chondroitin sulfate. They form the gel-like matrix of the ground substance of our tissues, especially in connective tissue, such as tendons, cartilage, skin and bones. These “gels” are the glue that holds us together. Glycosaminoglycan chains fill most of the space between our cells, providing mechanical support to tissues while still allowing the diffusion of nutrients, metabolites and hormones between the blood and tissue cells. The gel-like matrix, together with its GAGs and structural and adhesive components (collagen and elastin), forms the architectural framework of the body. Dietary sulfur is related to the production of GAGs. This is especially important during growth and development, and when connective tissue metabolism becomes active for support of healthy tissues. Sulfur also is needed for amino acid metabolism and hormone synthesis, and is a key factor in the body’s natural defenses. It is a component of important sulfur amino acids, including methionine, cysteine and glutathione. Vitamin C for Additional Joint Support Source Naturals has added vitamin C to its MSM tablets because C also is crucial to connective tissue. Vitamin C was first identified as essential because of its role in preventing the classic deficiency disease, scurvy. Scurvy is the total breakdown of collagen, the connective protein that binds tissue together. Although scurvy is rare today, vitamin C still is associated with support for joint function. Over-Processing & the Modern Diet We should be able to get sufficient MSM from our diets. It is a naturally occurring form of organic sulfur found mainly in protein-rich foods, such as eggs, fish and lean meat. However, today’s over-processed American diet may provide low amounts of sulfur. In this situation, supplementation may be advisable. MSM: A Versatile Nutrient Because sulfur is vital to all our body tissues, MSM is a versatile nutrient with a wide range of uses. Source Naturals offers MSM in a 750 mg potency with 125 mg of vitamin C added per tablet. It is sold in 60, 120 and 240-tablet bottles. MSM also is available in a high-potency powder, in 4 oz and 8 oz containers.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=176) Joint Response and Ultra Joint Response 
Date:
June 02, 2005 01:01 PM
Many people are unaware of the multiple body systems involved with joint health. Source Naturals ULTRA JOINT RESPONSE™ is a Bio-Aligned Formula™ that goes deep to bring alignment to these multiple systems. It features structural building blocks, tissue production cofactors, and ingredients that aid the body’s mechanisms for soothing relief and antioxidant defense. Joint Support Formulations You can use ULTRA JOINT RESPONSE alone or as the core of your healthy joints program, complementing it with additional potencies and ingredients. These include: GLUCOSAMINE CHONDROITIN WITH MSM™, MSM Cream, SAME, CM COMPLEX™ Cetyl Myristoleate, and BROMELAIN. For muscle discomfort and fatigue, Source Naturals also offers you FIBRO-RESPONSE™ Bio-Aligned Formula. ULTRA JOINT RESPONSE™: BIO-ALIGNED FORMULA ULTRA JOINT RESPONSE uses scientifically researched ingredients and nutritive co-factors for a comprehensive approach to soothing, lubricating, rebuilding and aligning connective tissue, joints, tendons and ligaments. MSM dietary sulfur, glucosamine and sea cucumber provide structural building blocks that are necessary to help maintain the integrity of joints and connective tissue. Vitamins A, B-6 and C, zinc, manganese, and copper act as co-factors or parts of enzymes that play a role in connective tissue formation and maintenance. Various soothing herbs, rich in polysaccharides and other constituents, assist the body’s natural mechanisms for soothing relief. Finally, N-acetyl cysteine, grape seed, beta carotene, vitamin C, zinc, selenium, horse chestnut, turmeric, and quercetin support the body’s natural antioxidant response, thereby helping maintain the health and integrity of joints and tissues (specifically cell membranes). GLUCOSAMINE CHONDROITIN WITH MSM: HOT RESEARCHED INGREDIENTS For added support, Source Naturals offers you a formula that combines higher potencies of the most popular joint nutrients: glucosamine sulfate, chondroitin sulfate and MSM. GLUCOSAMINE CHONDROITIN COMPLEX WITH MSM provides the same amounts of chondroitin and glucosamine shown in recent research to support healthy joints—along with MSM, vitamin C, and molybdenum, for a more powerful product. Together, these ingredients promote joint, tendon and ligament flexibility and easy joint movement. FIBRO-RESPONSE: BIO-ALIGNED FORMULA Dealing with the muscle discomfort that affects millions in our society requires more than alleviating fatigue. FIBRO-RESPONSE influences specific body systems and tissues involved in joint health and muscular metabolism. Malic acid and magnesium, supplied in the same amounts used in recent research, help support muscular energy production, along with coenzyme Q10, lipoic acid and B-complex vitamins. MSM, copper, manganese, molybdenum, zinc, vitamin C, and beta carotene support healthy connective tissue, which is essential for proper joint and muscle function. Key ingredients, including N-acetyl cysteine and silymarin aid the liver in eliminating toxic waste from blood and tissues. Ingredients including lipoic acid, selenium, N-acetyl cysteine, and coenzyme Q10 support antioxidant defense, thereby helping to maintain tissue integrity. And ginkgo and GABA are among the ingredients that support clear focus and stress reduction. LIFESTYLE TIPS FOR HEALTHY JOINTS: A STRATEGY FOR WELLNESSSM Healthy lifestyle habits should be part of your individual strategy for joint wellness. Watch Your Weight: Population-based studies, including the well-known Framingham study, have consistently shown a link between obesity and challenges to joint health. Excess weight causes pressure on joints, and can speed the rate at which cartilage wears down. Eat Healthy: To support healthy joints, increase your intake of omega-3 fatty acids from salmon, sardines, flax seeds or flax oil, avoid excess protein intake, and replace animal with plant proteins when possible. You should also eat lots of organically grown fruits and vegetables, and eliminate polyunsaturated and hydrogenated oils. Exercise Regularly: Regular physical activity helps lubricate cartilage, strengthens muscles around joints, and promotes weight control. An exercise program geared to joint health includes stretching, mild weight training, and low-impact aerobics. Rest and Relaxation: Regularly scheduled rest gives your body time to recover and rebuild, allowing you to make the most of your exercise program. It’s important to know when to slow down. Supplementation: In addition to the formulas described above, Source Naturals offers a range of products that can supplement your strategy for joint wellness. These include the pineapple enzyme BROMELAIN; SAMe, a natural compound formed from the amino acid methionine, which has been found to support joint comfort and mobility; and CM COMPLEX™ Cetyl Myristoleate, a fatty acid ester shown in recent research to reduce joint discomfort.
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