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Hesperidin, a flavonoid, can be used to reduce skin damage caused by constant sun exposure VitaNet, LLC Staff 8/9/18
Benefits Of Zeaxanthin Darrell Miller 2/7/12
Artichoke Leaves Provide Stimulating Digestion Benefits Darrell Miller 2/22/08
Fight Histamine With Quercetin Darrell Miller 2/11/08



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Hesperidin, a flavonoid, can be used to reduce skin damage caused by constant sun exposure
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Date: August 09, 2018 09:53 AM
Author: VitaNet, LLC Staff (support@vitanetonline.com)
Subject: Hesperidin, a flavonoid, can be used to reduce skin damage caused by constant sun exposure





Hesperidin, a flavonoid, can be used to reduce skin damage caused by constant sun exposure

Melanin protects skin from the sun's ultraviolet rays, which can burn the skin, and over time, could reduce its elasticity and cause a person to age prematurely. Suntanning occurs because exposure to sunlight causes the skin to produce more melanin and to darken.The sun's rays make us feel good, and in the short term, make us look good. But our love affair isn't a two-way street. Exposure to sun causes most of the wrinkles and age spots on our faces. Consider this: One woman at age 40 who has protected her skin from the sun actually has the skin of a 30-year-old!

We often associate a glowing complexion with good health, but skin color obtain from being in the sun – or in a tanning booth – actually accelerates the effects of aging and increases your risk for developing skin cancer.

Key Takeaways:

  • One study induced UVB damage in hairless mice to assess whether a flavonoid, hesperidin, would prove protective.
  • Mice in the hesperidin group received 100 milligrams of the flavonoid for every kilogram of body weight, daily.
  • The rodents were irradiated at 48 hour intervals, over a period of 12 weeks, with higher doses of UVB exposure occurring in incremental levels.

"Citrus lovers, rejoice: New research has found that a flavonoid found in citrus can help prevent skin damage brought about by ultraviolet radiation. The study, published in BMC Complementary and Alternative Medicine, has found that hesperidin can protect against photoaging caused by ultraviolet B (UVB) radiation, and prevent wrinkles, skin thickening, and inflammation."

Read more: https://www.naturalnews.com/2018-08-03-hesperidin-a-flavonoid-can-be-used-to-reduce-skin-damage-caused-by-constant-sun-exposure.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5700)


Benefits Of Zeaxanthin
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Date: February 07, 2012 08:14 AM
Author: Darrell Miller (support@vitanet.net)
Subject: Benefits Of Zeaxanthin

With aging, our eyes and the associated muscles weaken. They can degenerate and lose our ability to see properly. Eyes enable us with vision to see the world, and losing the eyesight will halt affect our daily activities and movements. People are frequently worried about losing their sight, and try to find supplements that can prevent the loss of vision. However, this debility can be prevented.

Supplements should be ideally be all natural, healthy, and with no side effects. Zeaxanthin is an important nutrient for eye health. This is found in found in green leafy vegetables, and also in other foods like eggs. Zeaxanthin fulfills most of the requirements that most people look in a supplement.

WHAT IS ZEAXANTHIN

Zeaxanthin and lutein are carotenoids that filter out the harmful high-energy wavelengths of light, and also act as antioxidants in the eye. This helps to maintain and protect healthy eye cells. Out of the six hundred carotenoids found in nature, only these two, Zeaxanthin and Lutein are deposited in high quantities in the retina (macula) of the eye. Unfortunately, our body does not synthesize the zeaxanthin and lutein it requires.

This is the reason why green vegetables, eggs and other sources of these carotenoids are essential to proper nutrition. Daily intake of zeaxanthin and lutein through diet, beverages, fortified foods or nutritional supplements and is very important for the protection and continuation of good eye health.

Studies have indicated that zeaxanthin and lutein can help to lessen the chance of chronic eye illnesses, including cataracts and age-related macular degeneration (AMD).

Zeaxanthin, is also a bioflavonoid, that besides its benefits to ocular health, has been linked to providing many health benefits, including its anti-inflammatory property. Because of zeaxanthin being a carotenoid category bioflavonoid, its main action is over the blood vessels; it works by supporting the blood vessels around the retina area with their proper function.

ZEAXANTHIN BENEFITS

Zeaxanthin is both an anti-inflammatory phytochemical and an antioxidant; hence this has been used as a preventative measure for macular degeneration and cataracts. Its antioxidant properties keep eyes from being damaged from the harmful ultraviolet rays of the sunlight. Overall, zeaxanthin keeps the eye healthier, and looking younger.

ZEAXANTHIN AGAINST CATARACT: Our natural eye collects and focuses light on the retina, and to properly provide this function continuously, the lens must remain clear throughout life. A major cause of cataracts is oxidation of the lens, which clouds it. Antioxidant nutrients, like zeaxanthin and lutein neutralize the free radicals or the unstable molecules associated with this oxidative stress associated with retinal damage. Thus, these phytochemicals play a role in cataract prevention. Higher dietary intakes of vitamin E, zeaxanthin and lutein can considerably reduce the risk of cataract formation.

ZEAXANTHIN AGAINST AGE-RELATED MACULAR DEGENERATION (AMD): Zeaxanthin and lutein reduces the risk of AMD. In fact, studies like AREDS2 (Age-Related Eye Disease Study) are being conducted with supplements containing ten mg lutein along with two mg zeaxanthin each day, how it affects or lowers the chance of developing this degeneration.

FOOD SOURCES OF ZEAXANTHIN

Zeaxanthin is naturally found in some green leafy vegetables like kale and spinach. Other sources of zeaxanthin include egg yolk, yellow squash and bell-peppers. This makes zeaxanthin available as a completely natural nutrient, with no side effects.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2559)


Artichoke Leaves Provide Stimulating Digestion Benefits
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Date: February 22, 2008 10:46 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Artichoke Leaves Provide Stimulating Digestion Benefits

The leaves from the plant of this familiar food are found to be beneficial to our digestion and metabolism, potentially reducing cholesterol. The artichoke has long been eaten as a vegetable, and has been ascribed many beneficial attributes. Artichokes were cultivated in the ancient Mediterranean and enjoyed great popularity in the thriving Roman Empire. From then until its mid-16th century reemergence, the artichoke hovered in sporadic obscurity.

Greek philosopher Theophrastus, a recognized naturalist, wrote of artichoke cultivation in Sicily and Italy around 300 B.C. Several centuries later, physicians and naturalists in Greece and Rome collected and recorded information on the health remedies resulting from intake of the artichoke and its preparations. The artichoke was also considered an aphrodisiac and a delicacy; to this day that estimation still remains.

Along with possessing a pleasantly robust and slightly bitter flavor, the fleshy lobes of the artichoke contain vitamins A and C, dietary magnesium, folic acid, fiber, as well as potassium and manganese, among other essential nutrients.

But the story doesn’t end there. The oft-thrown away serrated leaves of the artichoke plant, a member of the thistle family, contain even more health benefits than their edible counterpart. What most people are familiar with is actually the edible flower bud of the artichoke plant.

The plant’s leaves contain two key substances with health-giving attributes, the main one being cynarin. What is fascinating about this compound is that fresh artichoke leaves only contain trace amounts of cynarin. During the extraction and drying process, the levels rise due to chemical changes that occur during the process. Artichoke leaf extract contains beneficial levels of this compound that provides maximum benefit when ingested. Before more potent pharmaceuticals were developed by drug companies, synthetic cynarin preparations were prescribed to patients with high cholesterol.

Cynarin stimulates bile secretion in the liver and gallbladder; working as a digestive aid to break down fats and cholesterol. Additionally, increased bile production assists the digestive track in eliminating toxins from the liver.

Bile is formed in the liver, created by the combination of cholesterol and triglycerides. Often times these two terms are considered negative, but not all cholesterol is bad cholesterol. Some forms are necessary for normal body function. Once the bile is formed in the liver, it is stored in the gallbladder. Bile not only works to eliminate toxins, it also emulsifies fats to allow them to be digested and metabolized. Without bile the digestive track would be a disaster, and the body would be unable to absorb fat soluble vitamins.

The process by which artichoke leaf extract is thought to lower cholesterol levels is made up of two parts. More bile means the liver has more power and efficiency in breaking down and eliminating cholesterol. In addition to the increased ability to get rid cholesterol, artichoke leaf extract has been shown to inhibit cholesterol production in the liver. This second attribute is thought to come from the levels of luteolin in the extract.

Luteolin, a flavonoid, is an antioxidant efficient at fighting free radicals and reinforcing the functions of the immune system. Additionally, luteolin has been shown in studies to increase carbohydrate metabolism and prevent LDL-cholesterol oxidation.

Medical science is only beginning to reveal the details of how artichoke leaf extract works to improve cardiovascular and digestive health, while ancient physicians and traditional healers had a hunch all along.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1722)


Fight Histamine With Quercetin
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Date: February 11, 2008 03:48 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Fight Histamine With Quercetin

Quercetin is one of the more powerful of the body’s antioxidants, and it can also be used to reduce the rate of histamine release by the body normally initiated by contact with an allergenic substance (for which your immune system has designed an antigen). We shall examine the biochemical mechanism which this is achieved, but first let’s have a closer look at quercetin and what it actually is.

Quercetin is what is known as a phytochemical, which is simply the scientific name for a chemical that is naturally produced by plants. Other phytochemicals include vitamin C and omega 3 fatty acids, so the term is very broad ranging for any substance that is produced by plants. It is commonly known as a flavanol, one of a family of compounds known as flavonoids that give color to plants.

It is a very active flavonoid, with very powerful antioxidant properties, in addition to acting as an anti-histamine and anti-inflammatory. Histamine is an amine released as part of the body’s immune response to allergenics, and quercetin inhibits its manufacture and release. This amine is an irritant and can itself cause inflammation and the other symptoms associated with allergies such as runny and itchy eyes, a stuffy nose, sneezing and itchy spots. Quercetin can be used to alleviate these symptoms by blocking the manufacture in the body of the histamine that causes them.

It demonstrates other anti-inflammatory properties such as alleviating the symptoms of arthritis, and also helps to destroy free radicals in the body through its strong antioxidant properties, but before we discuss how it does this we shall have a closer look at the mechanisms used in its effect in inhibiting histamine.

Calmodulin is a protein that is used to transport calcium ions, Ca++, across the membranes of certain cells in the body, and by doing so it helps to mediate a number of biochemical processes within the body, among them the immune response and inflammation. It should not be thought these are always unwelcome responses: on the contrary, they are the body’s way of reacting to foreign bodies and preventing more serious conditions from developing.

However, there are instances where the body can become sensitized to certain substances and overreact to their presence leading to conditions such as hay fever or, considerably more serious, asthma. These are just two of the undesirable manifestations of the human immune system that we would be better without. What quercetin does is to prevent calmodulin from properly binding to certain enzymic proteins and so suppress the effect of these proteins. Among these are the enzymes that control the secretion of histamine from mast cells.

Mast cells are found mainly in areas prone to injury and at the interface between internal tissues and outside world, such as the nose, mouth, lungs, eyes, blood vessels and feet. They contain granules rich in histamine that degranulate and released the histamine when the immune system detects foreign bodies such as pollen grains and dust mites, especially when the body has created antigens against them.

Quercetin suppresses the release of histamine from the granules in the mast cells by preventing the degranulation. The release of the histamine is not completely halted, but its effects are reduced and quercetin is used in the treatment of asthma where it is believed to help reduce the symptoms by reducing histamine-induced swelling in the airways.

A similar application of this flavonoid is in reducing the inflammatory response to arthritis, the main cause of the swelling of this painful condition. Your skin can also be affected by inflammation that is partially controllable by quercetin. Collagen and fibronectin biosynthesis is increased that help to maintain not only healthy joints, but also to speed up the healing of wounds and repair damaged nerves. It is also believed that quercetin can hold back the effects of aging on the skin, and slow down the formation of wrinkles.

There are other applications of this versatile flavanol, including its effect on acute prostatitis where it reduces oxidative stress and the accompanying inflammation of the prostate gland. In fact, it is believed to have positive effect on many conditions caused by free radical oxidation and excessive reaction by the immune system causing inflammation. Apart from the allergies and arthritis previously referred to, quercetin is believed to have been effectively used in the treatment of gout, macular degeneration and heart disease, and it can also help to prevent the oxidation of low density lipoproteins (LDL) responsible for transporting cholesterol to where it is needed to repair major blood vessels.

When these lipoproteins become oxidized by free radicals then the cholesterol associated with them tends to be excessively deposited in the arteries it is meant to be repairing, and lead to atherosclerosis. This condition can lead to heart failure or to strokes if the blood vessels are in the brain.

Studies have indicated that the flavonoid might help to prevent certain cancers by preventing the nutrition of some types of cancerous cells, effectively killing them. Due to its phytoestrogen properties, quercetin can be used to bind to the sites in cancerous cells that are receptive to estrogen and so prevent their growth. Many types of cancerous cells need estrogen for their growth and proliferation, and phytoestrogens mimic the effect of this hormone. However, these are laboratory studies, and more work is required.

More certain is the effect of quercetin on heart disease due largely to the aforementioned control of cholesterol deposition in your arteries, but also through its ability to strengthen the capillaries. However, when all things are considered, it is in the properties of this non-allergenic bioflavonoid to fight histamine release that it finds it’s most popular and effective use.

So what is the best way to take quercetin? Like most bioflavonoids, it is available naturally in the majority of plant foods. Particularly rich sources are broccoli, red onions, red apple skins, black tea, red wine, red and purple berries and almost all dark green leafy vegetables.

However, the name of the game these days is to take measured doses, and while you should continue to eat these foods, you can also receive controlled doses by use of supplements. From 200 to 500 milligrams thrice daily is a good average dose, depending on the severity of your immune reaction or allergy. Bromelain is believed to improve its absorption in the gut, and quercetin is frequently provided with bromelain, which itself is also a good treatment for allergies and excessive response of your immune system to irritation.

Bromelain is an enzyme, generally extracted from pineapple, and treatments higher than the above doses of quercetin with or without bromelain are available online, although like any natural remedy you should inform your own physician of the dosage you are taking.

There is no better non-allergenic bioflavonoid to fight histamine and its potentially unpleasant effects on your body than quercetin.



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