|
Search Term: " hypohalamus "
Turmeric may help boost memory, lower Alzheimer's risk: study   
Date:
January 26, 2018 07:59 AM
Curcumin is one of the chemicals that helps to make up turmeric. While turmeric has shown great benefits in the past, this specific portion is showing great promise in memory and even Alzheimer's disease. It was found to help improve memory in people who didn't have dementia and help clear up the plaques formed by Alzheimer's disease. It is also thought that this spice, highly common in Indian cooking, is another reason why there is such a low prevalence of Alzheimer's disease in India. Key Takeaways:
"Those taking curcumin also had mild improvements in mood, and their brain PET scans showed significantly less amyloid and tau signals in the amygdala and hypothalamus than those who took placebos." Read more: https://www.outlookindia.com/newsscroll/turmeric-may-help-boost-memory-lower-alzheimers-risk-study/1237371
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5506) What Happens to Your Brain When You Go on a Diet 
Date:
September 27, 2017 12:14 PM
People often go on diets because they want to lose weight. A good way to diet is by just substituting what you eat with healthier things. It's not good to eat much less, though, because your body needs certain nutrients and a certain amount of calories. This tells you what can happen to your brain if you do choose to diet. It might make you think a bit before doing so or at least before choosing an extreme one. Key Takeaways:
"In fact, though the risks of yo-yo dieting have been contested, one 2016 study found that repeatedly going through these starvation cycles prompts your body to gain more weight." Read more: https://www.nbcnews.com/better/health/what-happens-your-brain-when-you-go-diet-ncna802626?cid=public-rss_20170920
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5286) Maca Root And Your Health
Date:
September 28, 2016 07:50 AM
Maca, (Lepidium meyenii) also Peruvian herb is a biennial herb indigenous to Andes, Peru. It’s also grown in Brazil and Bolivia. It’s cultivated for its fleshy hypocotyl and tap root which is a root vegetable and a medicinal herb.
Brief history For over 2000 years, Maca root has been used by the ancient Incan culture for medicinal uses. They highly revered the plant for its legendary ability to offer mental clarity and energy as well as enhancing sex drive.
Today, Maca root is medicinal and health benefits such as:
Maca root and Energy improvement
Maca contains vitamins, fatty acids, proteins, and minerals. These are elements to naturally support energy supporting as well as aid in injury recovery. Those who have used maca root in powder form have testified that it makes them awake, driven and energized. They even prefer it over caffeine as it doesn’t give jitters.
Clinical studies have revealed that maca is useful in maintaining positive energy levels and reducing anxiety and depression. It’s also important in regulating the hypothalamus, which improves the functioning of pituitary glands and thus balancing focus and energy. Researchers believe this is enhanced by balancing blood sugar levels. Maca root holds many health benefits, if you are over the age of 50, you should be taking maca root daily to help balance hormones and feel better.
Reference URLs
https://draxe.com/top-5-maca-root-benefits-and-nutrition/
//www.globalhealingcenter.com/natural-health/7-benefits-of-maca-root-for-women/
//www.webmd.com/sex-relationships/guide/the-truth-about-maca
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3316) The Dangers of Vegetable Oil
Date:
July 21, 2015 05:23 AM
More often than not, when we see the words vegetable oil, we assume that it is good for us since vegetables are essentially beneficial for the body. The truth of the matter is that this kind of oil is mostly derived from seeds such as sunflower, soybean and corn, not from any kind of vegetable at all. Aside from this, their extraction requires a process that uses up a lot of energy and is not good for the environment.
Trans Fats Unsaturated fats, otherwise known as trans fats, are fats that are usually solid at room temperature but processed in such a way that they are not when they come in the form of oils derived from seeds. These contribute to diabetes, heart disease, cancer and obesity. The sad part is that although there are so many calls to action regarding minimizing the presence of trans fats in food; there is very little that has been done regarding their presence in vegetable oils. How trans fats were developed or discovered will show how scary it actually is. It was discovered while looking for an alternative to tallow which is an ingredient for candle wax. It was cheap and convenient to harness and use. The reason why it is widely used is because of its extended shelf life. It can also be reused several dozen times for frying without changing flavor or adding a rancid taste to the food fried in it. Mutated Fats The process of extracting the oils from their sources requires a lot of heating and, for some, even exposure to acids and metals which contribute to the "mutation" that these oils undergo. Hydrogenated vegetable oil confuses our bodies into thinking that they are good for us. This is mainly due to the processes that changes their form. HVO alters the structure of our cells, making them weak and lowering the good cholesterol as well as raising the bad. Our bodies welcome these fats and do not treat them as a danger although their presence does, in fact, increase the risk of heart disease, diabetes and other diseases. Imbalances Vegetable oils can also cause imbalances in the composition of our fatty acids. Omega 3 and omega 6 fatty acids are not produced by our bodies. Therefore, we need to supplement these from our diets and daily consumption in pretty much the same amounts to balance their presence in the body. Polyunsaturated fats from HVO that causes the mutation in our cell membranes can lead to oxidative chain reactions which are harmful to our cells. In essence, our cells are made weak and the chances of alterations to our DNA are increased. Omega 6 is abundant in HVO because it helps to slow the deterioration of the vegetable oil. It can cause an imbalance to the cell membrane causing inflammation in various parts of the body. One component of Omega 6 that is highly dangerous is linoleic acid. It has been linked to obesity, high levels of bad cholesterol and even damage to the brain's hypothalamus. These are just a few of the dangers that come with using so called vegetable oils. These dangers are kept under wraps because of the massive income that the food industry will lose if it changes the oils used for cooking and preparing food.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3174) Can Low Selenium Affect Thyroid Functions?
Date:
August 08, 2014 10:01 PM
Human thyroid glands are small glands with a very important function. The major function of thyroid glands is to regulate body metabolism. There are two main hormones produced by thyroid glands; thyroxin (T4) and triiodothyronine (T3). The secretion of these 2 hormones is based on the feedback mechanism of hypothalamus and pituitary glands. These hormones influence every body cells- they control the rate at which your body accumulates and uses fat, help to regulate body temperature and also heart rate. In addition, thyroid glands produce calcitonin, a very important hormone that regulates the amount of calcium in the body. There are the major types of thyroid diseases, Thyroid cancer, Hyperthyroidism, Hypothyroidism and Benign disease. But what is the role of selenium in thyroid functions? Selenium deficiency Selenium deficiency is not common in healthy adults, but it is common in people with digestive disorders causing low absorption, or those with severe inflammation arising from chronic infection. Research shows that low selenium does not cause illness by itself, but due to its role in immune functions, it makes a body susceptible to biochemical, nutritional and infectious diseases. But this does not mean that selenium has no direct influence on thyroid functions. Adequate selenium supports the production of thyroid hormones, protects thyroid glands from the adverse effects of excess iodine in the body, and will also improve body metabolism.
Selenium is very important and it is always healthy to ensure your normal selenium level. For example, selenium supplements are used to treat autoimmune thyroid condition. Studies have found that selenium supplementation lowers thyroid inflammation. These findings are backed by the fact that selenium increases thioredoxin reductase and glutathione peroxidase activity, and also lowers the toxic concentration of lipid hydro peroxides and hydrogen peroxides which results from the production of thyroid hormones. Selenium prevents thyroid tissue damage. Selenium is very important because it lowers the level of thyroid peroxides in the blood. In addition, selenium is vital for conversion of T4 to T3. T3 is the active form of thyroid hormones. Low T3 causes hypothyroidism. How to obtain selenium? If you think your body is deficient of selenium, it is good to seek medical care immediately. Thyroid glands are very important for the body functions. Selenium supplement is a good solution to thyroid function. But long term use of selenium supplement would cause other complications such as white blotchy nails, hair loss, gastrointestinal upsets, fatigue, irritability, garlic breath odor, and mild nerve damage. In addition, very high selenium in the body may cause hyperthyroidism. In addition, clinical test for use of selenium supplements has found that it predisposes users to the risk of prostate cancer. Though this has not yet been proven. This makes selenium rich foods the best way to increase the level of selenium in the body. Some of the food rich in selenium includes; crimini mushrooms, shrimp, tuna, cod, scallops, chicken, halibut, salmon, shiitake mushrooms, brazil nuts, lamb eggs, and turkey. Brazil nut is particularly very rich in selenium, taking one or two in a day will significantly improve the selenium level and also boost your immune system. Is selenium important for thyroid function? Yes, selenium level is very important and low selenium. References
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3155) What Is Solaray Phosphatidyl Serine?
Date:
January 04, 2013 01:00 PM
Phosphatidyl Serine : What are its Health Benefits? Phosphatidyl serine is a popular medication for people who need to improve their memory and mental well-being. Not only does it work to improve your memory, it also has other health benefits to your body. What is Phosphatidyl serine? Each cell in your body has a membrane that protects its internal contents from the surrounding environment as well as control what enters the cell and what goes out. This serine is one of four major phospholipids that make up part of this membrane. This lipid is found in high concentrations in the cell membrane that surrounds the hippocampus of the brain, which is associated with your memory. How does Phosphatidyl serine supplementation benefit you? As you age, the cells around the hippocampus also lose their potential to fully function. This makes your mental processes to slow down. Providing your body with this serine will provide material necessary to rejuvenate the cell membrane, thus improving your memory. This compound is useful in stressful situations. Some situations need you to concentrate on what you are doing and yet you may be tired. For example, you may face an exam which needs you to be at full concentration and be alert at all times. This serine helps boost your memory and concentration, which in turn increases your focus thus improve learning. When you get stressed, your body releases cortisol which damages the tissues of the hypothalamus in your brain. To reduce the effects of this hormone, you need Phosphatidyl serine to repair the tissues that have been damaged. This helps you to retain your memory after a stressful situation. For your body to function properly, the cell membrane surrounding various organs has to be in good health. Phosphatidyl serine will work to improve the health of various membranes, such as myelin sheaths found in the central nervous system. The compound is found in small amounts in foods such as liver and soy, therefore it is advisable to use supplements which provide a high level of the compound.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2804) The Health benefits of P-5-P
Date:
July 20, 2012 07:51 AM
P-5-P or Pyridoxal-5-phosphate P-5-P or the most commonly called Pyridoxal-5-phosphate is known to be the most active form of the Vitamin B6. This is known to be converted from organic compounds pyridoxal, pyridoxine and pyridoxamine. The Vitamin P-5-P is a coenzyme which support several other enzymes in the body which play a important role in biosynthesis. This also makes optimum use of the vitamin B6 by improving the body metabolism and many other biological process as well. The vitamin B6 traditionally comes in the form of pyridoxine hydrochloride which the body finds difficult to synthesize in its existing state. Hence, this pyridoxine hydrochloride is processed and is formed as Pyridoxal-5-phosphate to help the body to use the vitamin B6 effectively. There are a lot of benefits of the vitamin P-5-P Let us have a look at some of them. Pyridoxal-5-phosphate uses the information from the genes ad helps to produce proteins.P-5-P is also helpful in the formation of hemoglobin, histamine and neurotransmitters and is also helpful in the metabolism of amino acids, fats and glucose.Pyridoxal-5-phosphate also helps in the conversion of dopa which is a useful substance used in the treatment of Parkinson's disease. Dopa is converted to dopamine which is a neurotransmitter which is produced in the brain and is released by the hypothalamus. Food Source The P5P is also helpful in the utilization of the food sources for the formation of energy and also helps in the easy release of glycogen which is the stored energy.P5P also converts glutamate into GABA which is gamma amino butyric acid which is again a neurotransmitter which is known to be found in the mammals. This is found in their central nervous system.The Pyridoxal-5-phosphate also helpful in the process of decarboxylation which is the conversion of histidine to histamine. This also converts SAM-e to propylamine which is known to be a precursor of polyamines.The Vitamin P5P is also responsible to lower the homocystenie levels which are caused by the intake of high amounts of methionine.The Vitamin Pyridoxal-5-phosphate helps in the treatment of irregular heartbeat , which is a condition termed as arrhythmia.This plays a important role in the treatment of myocardial infections. This prevents the blood platelets from sticking to each other which usually causes blood clots.The enzymes produced by the Pyridoxal-5-phosphate also helps in the formation of different kinds of amino acid reactions which keeps the carbon ions stable. This process is very important in the metabolism of the cells.The P5P also helps in the metabolism of the amino acids. Here it helps in converting methionine to cysteine and also converts tryptophan to niacin.Pyridoxal-5-phosphate also plays a vital role in the formation of glucose. This process is known as gluconeogenesis.This also acts a important co-enzyme in the process of glycogenolysis which happens in the liver and muscles and this is known to be a reaction which occurs due to presence of glycogen.The P5P also helps in the formation of antibodies and also assists in the process of hemoglobin synthesis as well. To keep it simpler, the vitamin P5P performs many functions which is very beneficial to the whole human body. The P5P deficiency can also happen in many individuals and even such symptoms are hard to identify. Any person suffering from the P5P deficiency will have symptoms like muscle weakness, irritability or depression. Consulting a physician and taking necessary supplements will help to overcome the P5P deficiency.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2668) Can Iodine And Potassium Be Used For Thyroid Health?
Date:
September 15, 2011 02:11 PM
Thyroid Hormone Production The thyroid gland basically is the part of the body that produces thyroid hormones as the its name suggests. It could be found in the neck right around the front area, somewhere around the thyroid cartilage which is more familiar to us as the adam’s apple. The primary function of the thyroid hormone is to regulate and maintain proper metabolism. I addition it also extends its purpose to processes like energy conversion for the body and the body’s processing of other hormones and vitamins to stimulate proper growth and maturation. Commonly when we refer to thyroid disorders, we refer to thyroid production being out of balance. It could either be too high or too low. In the case of overproduction of these hormones an overactive thyroid is usually the culprit and this is called hyperthyroidism. In the case of underproduction caused by an underactive thyroid the disorder is called hypothyroidism. Thyroid issues also have been noted to be more prevalent in women than in men. The production of these hormones although done actually by the thyroid the process does not start there. The hormone synthesis process which will eventually produce thyroid hormones begin in the part of the brain called the hypothalamus. This is where the TSH or thyroid stimulating hormone is being released from and it then is transported to the thyroid gland via the blood. Then the two thyroid hormones, L-thyroxine or T4, and triidothyronine or T3 are produced. In this process, it is important that regulation occurs and when any disruption happens this is where the imbalances start, either overproduction or underproduction of the hormones occur. A gland known as the pituitary is the key to all this, also located in the brain it can sense how much hormones are in the blood and adjust accordingly to maintain this delicate balance. Iodine and the Thyroid Worldwide the most common cause of any thyroid disorder is iodine deficiency. Ample amounts of dietary iodine are needed to produce the thyroid hormones. It is important that we get the correct amount of iodine from our diets, it is so essential that in the US many food products are fortified with iodine and the reason being is that iodine in natural food sources alone are not enough since our food whether it be crops or meat gets its iodine from the soil and our soil is low in iodine content thus the fortification of many of our food products to avoid any thyroid disorders. Potassium and the Thyroid Potassium is a very important mineral in the body to maintain good health. It is an important electrolyte and help conduct electricity in the body. In terms of its link with thyroid health, numerous studies have shown that there is an association between low potassium levels and thyroid issues especially hyperthyroidism and in more severe cases it even has been found to be the cause of an overactive thyroid and as such potassium supplementation has been commonly used as treatment to provide relief.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2432) How Does Progesterone Cream Help Ease Hot Flash Symptoms?
Date:
June 21, 2011 11:01 AM
Progesterone And Hot FlashesProgesterone cream is an all natural remedy for hormonal imbalances in the female body. It has grown in popularity in the past few years largely owing to very strong anecdotal evidence. Its use in the management of hot flashes has produced very encouraging results, and thus has become a mainstay of alternative treatment for vasomotor symptoms of menopause and premenstrual syndrome. Plants contain fats and oils that can be modified in the laboratory to partially synthesize progesterone. The active ingredient of most progesterone creams in the market is diosgenin, which is a plant sapogenin that occurs naturally in wild yams. Diosgenin has long been noted for its steroidal activity inside the human body, but it has been successfully converted to progesterone only recently. Reverses Estrogen Dominance The concept of estrogen dominance is central to the appearance of hot flashes. A group of medical professionals believe that vasomotor symptoms are brought on by fluctuations in hormonal levels, among other factors. While both groups of female sex hormones experience changes, progesterone is thought to approach near depletion in comparison with estrogen. Hence, the latter dominates. Progesterone creams work on the principle of reversing estrogen dominance. They are formulated to facilitate optimum absorption into the body. While their active ingredients, such as diosgenin, have been noted to produce estrogen-like activities when unmodified, progesterone creams function exactly in the same manner as endogenous secretions of progesterone. Increases Progesterone Levels Hot flashes are often linked to changes in body temperature. It has long been postulated that hormonal imbalances have an effect on the hypothalamus, which regulates body temperature. It is believed that depleting levels of progesterone lead to a series of chemical reactions that confuse the biological thermostat, resulting in vasodilation of blood vessels close to body surfaces. Progesterone creams effectively relieve hot flashes because the active ingredients are capable of penetrating the part of the skin that leads to the blood vessels. There is very good evidence that topical applications of progesterone are readily absorbed. Since fats and oils from plants have high absorption rates, progesterone creams are certain to increase progesterone levels in no time. Normalizes Hormonal Changes There has not been any contraindication associated with the regular use of progesterone creams as most of them are formulated in concentrations suitable for use at any time of the day. In fact, it can be applied to the skin even in the absence of hot flashes to prevent any vasomotor symptoms. A growing of body of literature has noted its efficacy in managing hormone-related imbalances. More importantly, progesterone creams have shown great promise in stabilizing hormone levels in the long run, making it an ideal remedy for women suffering from premenstrual syndrome. Also, it is very likely to help women who are surgically menopausal as they experience very intense episodes of hot flashes that last until the natural age of menopause. Grab some progesterone today and feel the relief it can bring!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2344) How Does Taurine Help the Brain?
Date:
May 13, 2011 01:09 PM
Taurine is an amino acid often added to energy drinks. There have been several theories on how taurine affects brain chemicals and improve cognitive function. For many years, it has been compared to caffeine due to its effects on the human brain that appear to enhance mood. Its exact mechanisms of action remain a mystery to the scientific community, but recent studies are believed to be closing in. It has long been known that taurine crosses the blood brain barrier, allowing it to exert some effects on several neurotransmitters found in the central nervous system. It has been tied to the alleviation of many mental illnesses, such as epilepsy, post traumatic stress disorder, clinical depression, bipolar disorder, and anxiety, making it the subject of a number of studies in the past few years. Rebalances Brain Chemicals It has been postulated that taurine influences the activities of neurotransmitters in the brain, but only recently has brain scientists been able to actually track its activities in the brain. A team of researchers at Cornell University managed to find a site for the neurological activity of taurine, with initial results pointing to its relationship with gamma the neurotransmitter aminobutyric acid, or GABA. The researchers do not discount the possibility that taurine may even have a receptor of its own. Whether taurine interacts with brain chemicals is no longer debatable as it creates homeostasis in the central nervous system. It acts on receptors that the researchers discovered to be the same receptors present in GABAergic mechanisms. That being said, scientists remain inconclusive as to how its interaction with GABA receptors provides energy-boosting benefits as it is marketed in the food and drug industries. Prevents Neuron Damage The scientific community is convinced that taurine has neuroprotective properties. High levels of taurine in the brain have been observed to protect brain tissues from cerebral ischemia. Taurine has been linked to many metabolic pathways that are known to promote neurological health, such as the activation of glycine receptors and the regulation of enzymes called cysteine-dependent aspartate-directed proteases. In addition, taurine serves as antioxidants that protect nerve cells from cellular damage brought on by oxidative stress. The presence of taurine within cells reduces damage from calcium excesses and increases mitochondrial events. For decades, supplementation of taurine has benefited sufferers of brain ischemia, epileptic seizures, panic attacks, anxiety symptoms, and even alcohol withdrawal. Enhances Cognitive Function Taurine has already been associated with physiological functions the hypothalamus controls, such as sleep-wake cycle and responses to fatigue. In several laboratory studies, administrations of taurine by way of intraperitoneal injection have successfully induced social interaction in animal subjects. It is one of the amino acids that affect cognitive development, especially in children. While it is one of the most abundant amino acids in the brain, it is depleted as we age, making supplementation a good option. Protect your brain with Taurine by taking it daily!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2295) Why is Maca Called the Peruvian Ginseng and What Does this Herb Do
Date:
April 28, 2011 03:17 PM
Maca: Stress, Energy, Libido, and More.
Maca is a root vegetable traditionally grown at high altitudes in Peru. It is related to radish and turnip, both of which it resembles in appearance, size, and proportion. Its historical uses denote its adaptogenic properties, the reason why it is often called the Peruvian ginseng today. It is the subject of numerous studies underway, and preliminary results point to its effects on the endocrine system. Lepidium meyenii is a plant species that belongs to the Brassicaceae family, which comprises over three thousand species of edible plants called cruciferous vegetables. Hence, maca is related to many green leafy vegetables such as cabbage, broccoli and cauliflower, among others. Like these vegetables, maca contains an assortment of organic compounds that display bioactive properties. Lepidium peruvianum refers to the same species. Modern herbalists argue that it is a more accurate scientific name for maca, though Lepidium meyenii remains in use in the scientific community. Until only recently, maca was exclusively cultivated in the Andes of Peru. Due to an increased interest in alternative forms of medicine in North America and Europe, it has enjoyed a sudden surge in popularity in the past few years. Enhances Stress Resistance Maca is marketed as an adaptogen, a natural remedy for stress. It has been compared to ginseng a number of times, earning itself the moniker Peruvian ginseng. Maca and ginseng do not interact with hormones in the body but rather contain phytochemicals that directly act on endocrine glands, including the hypothalamus, adrenals, and thyroid glands. These organs are pivotal to better management of stress. Several herbalists argue that maca is even more potent than ginseng in that it is believed to affect almost all endocrine glands and create a homeostatic effect on the chemical compounds that they secrete. Modulates Energy Metabolism The nutritional profile of maca has been described to be a combination of the nutrients found in whole grains and green leafy vegetables. It contains significant amounts of amino acids and dietary fiber. Its carbohydrate content accounts for 60 per cent of its dry weight, with emphasis on its low glycemic index. Its active constituents enable its carbohydrates to break down at a slow pace and release glucose into the bloodstream without raising blood sugar levels. By so doing, it provides the energy needed to fuel physical activities and athletic performance for extended periods of time. Improves Sexual Performance Maca is a popular aphrodisiac. In the old days, Inca warriors consumed large quantities of maca roots for the sole purpose of achieving desired virility. In addition to its energy-boosting and stress-relieving effects, regular intake of maca impacts sexual health as it contains organic compounds that stimulate gonadal tissues, especially in men. Randomized clinical trials have observed that maca affects semen quality, increases sperm count, and improves sexual performance, making it an ideal choice of supplement for men. Maca root is an excellent herb for men and women. You can gain energy as well as a boost in energy with Maca root. Try maca root and feel the difference it can make on your life!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2284) Hoodia For Weight Loss
Date:
September 18, 2009 10:20 AM
The hoodia plant is a leafless, spiny plant. It is a succulent in the milkweed family. Hoodia can be found growing in South Africa and Namibia. The plant thrives in very high temperatures, taking years to mature. Bushmen from the Kalahari Desert in southern Africa have used hoodia for centuries to help fight off hunger during long treks in the desert. This ancient band of nomadic hunter-gatherers eats bite-size chunks to stave off thirst and curb their appetites on long hunting trips in the wilderness. In early 2004, the first supplements containing a hoodia compound were introduced in the United States. These supplements were intended to be an aid for obesity and weight loss. Hoodia contains an appetite-suppressing component that is similar in molecular structure to glucose, only stronger. This component is known as P57. It is responsible for sensing a signal to the hypothalamus which tricks the body into thinking it is no longer hungry. The P57 compound seems to increase the amount of ATP in nerve cells of the hypothalamus, which is the brain’s control center for regulating thirst, hunger, and temperature. ATP is an energy-producing molecule that is created from glucose. When ATP levels are increased in hypothalamic nerve cells, those nerve cells fire as if you had just eaten, even if you haven’t. Some people claim that hoodia works immediately for them, within twenty to thirty minutes of taking the capsules. However, more often, people require up to two weeks of taking regular doses before they start noticing significant results. These results include a reduced interest in food, a prolonging of time after a meal before being hungry again, feeling full more quickly, and a general sense of well-being. Studies that have been done on the effects and safety of hoodia are continuing in the United States and abroad. The prospects for the future development of this herb look very promising. Don’t make the mistake of believing that all you have to do is take a supplement of hoodia everyday and the fat will just disappear. While some claim that has been the case for them, the majority of dieters need more help than solely diet pills. It should be remembered that the only thing the hoodia does is suppress appetite. It does not improve a bad diet or address problems of overeating. It you have a terrible diet and ten to overeat even when you are not hungry, you will not receive any benefits from hoodia. If these things describe you, you first need to tackle those issues before considering hoodia. This herb will not build muscle or burn fat. Your muscles are fat burning machines and responsible for burning fat all day long, even when you are resting. The more you have the more fat you’ll burn. Your metabolism also plays a huge role in burning fat. The only way to build muscle and speed up your metabolism is to exercise. The stem of the hoodia plant is used to provide anorectic, aphrodisiac, and mood enhancer properties. Primarily, this herb is extremely helpful in treating diabetes, obesity, and weight loss. For more information on the many beneficial effects of hoodia, please feel free to contact a representative from your local health food store.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2082) Caralluma extract
Date:
August 24, 2009 11:32 AM
Caralluma is a succulent plant that is part of the cactus family. It can be found growing wild in Africa, the Canary Islands, India, and southern Europe, Sri Lanka, and Afghanistan. The herb has been used in Indian for centuries in order to curb appetite. It is a portable food for hunting and also an endurance enhancer. This herb was also used during periods of famine in order to curb appetite. The caralluma plant is part of the Apoxynaceae family. It has been eaten in rural Indian for centuries, raw, as a vegetable with spices, or preserved in chutneys and pickles. It is often found as a roadside shrub or boundary marker. Caralluma has been used as a portable food and thirst quencher for hunting. Caralluma is mainly used for its ability to suppress hunger and appetite, while enhancing stamina. Tribesmen on a daily hunt will often only pack some caralluma to sustain themselves, which is why it is commonly known as a famine food in India. The working class in India used this plant not only as an appetite suppressant, but also to increase energy and endurance. Caralluma can be coked as a vegetable, pickled, used in chutneys, or eaten raw. This herb seems to block the activity of many fat-promoting enzymes in the body. It forces fat reserves to be burned. One double-blind, placebo-controlled, randomized clinical trial on caralluma extract, which involved fifty people, showed significant reductions in all key indicators of weight loss. This plant is also believed to affect the appetite-control mechanism that is found in the brain. When we eat, nerves in our stomach send a signal to the brain’s hypothalamus. This is the appetite-controlling center. When the stomach is full, the hypothalamus informs the brain that it can stop eating. When a person feels hunger, it is the result of the hypothalamus sending a signal to the brain to eat. The interference with these signals, or even creating a sign of its own, is done by caralluma. Through this, the brain is tricked into thinking that the stomach is full, even if the person has not eaten. Patients who use caralluma have reported having more energy. Additionally, they tend to gain lean muscle mass while they lose fat. This herb not only reduces fat synthesis, but it also boosts the burning of fat. This makes more energy available for the body as a whole. The plant has no known toxicity or side effects. However, it is wise to consult a health care professional before supplementing with this, or any nutrient while on prescription medications. The entire caralluma plant is used to provide anorectic and energy boosting properties. The primary nutrients found in this herb are bitters principles, flavones glycosides, megastigmane glycosides, pregnane glycosides, and seponins. Primarily, this herb is extremely beneficial in dealing with low energy and obesity. It also acts as an appetite suppressant. For more information on the many beneficial effects provided by caralluma, please feel free to contact a representative from your local health food store.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2063) Hoodia Gordonii
Date:
December 10, 2008 10:48 AM
Hoodia Gordonii is a South African succulent plant of the family Apocynaceae. They are remarkable similar in appearance to cacti, although they are totally unrelated to them and grow predominantly in the region of Central Namibia in the south west of Africa, up to the southern regions of Angola. They are most commonly found in rocky ground and on the plains. There are several species of hoodia, some of them grown domestically, and it is Hoodia gordonii that is used as an appetite suppressant in hoodia weight loss pills. Although the plant has historically found use in the treatment of infections and gastric problems, most interest is displayed in its use by the bushmen of the Kalahari Desert to suppress their appetite during long hunting trips when food and water are scarce. The active ingredient was isolated in 1977, and given the name P57: the product is therefore often referred to as Hoodia P57. It was patented by its discoverers, the CSIR (South African Council for Scientific and Industrial Research) and a license granted to UK company Phytopram, who worked together with Pfizer to isolate the active ingredients and manufacture them synthetically. This was found to be very difficult, if not impossible, since any synthetic form of the extract failed to display any hunger-suppressant properties. Finally, the rights to the main ingredient were released by Pfizer in 2002, thus indicating that it was of no commercial benefit to them. The main problem they admitted with synthesizing P57 was not only the difficulty in doing so, but also that there were side effects of the extract on the liver caused by other components that could not be removed. No synthetic form of hoodia is therefore available, and only the natural plant is used in current Hoodia 57 preparations. The rights of the San Bushmen to the plant were recognized by the CSIR in 2002, and not only do they receive a proportion of the profits of marketing hoodia, but also the plant is protected with wild-harvesting licenses provided to only certain individuals and companies. Due to the rising popularity of the hoodia weight loss industry, the plant has been named as an endangered species in the wild. It is believed that the active ingredients are steroidal saponins that can fool the body into believing it is full. This theory is based upon the effect on appetite of glucose concentrations in the blood. Your appetite is controlled by the amount of unconverted glucose in your blood, and glycogen in the liver. When you eat carbohydrates, they are digested and converted into glucose which is absorbed into the bloodstream. Under normal conditions your blood glucose levels increase to a level where a signal from hypothalamus stops you feeling hungry. Insulin is then secreted from the pancreas to prepare your cells to use that glucose in the mitochondria to create energy by means of the Kreb's Cycle, or Citric Acid Cycle as it is also known. This reduces the concentration of glucose in the blood, and once it reaches a certain level the body begins to use its emergency energy supply, glycogen, that is stored in the liver. A signal then informs the brain that more glucose is needed. You then feel hungry again, and this cycle is repeated several times a day in a normally healthy person. This cycle is controlled by certain hormones in the brain, specifically in the ventromedial center of the hypothalamus, where it is believed that the ATP (adenosine triphosphate) availability controls the release of the hormones involved. ATP is the molecule of energy, and as the concentration of blood glucose and of glycogen drop, then the amount of ATP produced also drops and this is detected in the hypothalamus, which reacts by releasing ghrelin. Increased leptin increases the feeling of satiety and ghrelin increases the feeling of hunger. Serotonin acts on the brain to increase the effect of leptin in the hypothalamus, and therefore make us feel less hungry, or more satiated. It is believed that hoodia gordonii, or the Hoodia P57 component of it, fools the brain into believing that your blood glucose or glycogen levels have reached the point at which it should trigger a satiated response, so that you stop eating even though your ATP levels might be low. The steroidal saponins that it contains is believed to be ten thousand times more effective than glucose in stimulated the secretion of serotonin. Hoodia has also been found to contain a number of glycosides, including pregnane glycosides that some studies have indicated to help control appetite of the subjects tested. Most of these tests have been carried out on animals, although Hoodia weight loss preparations are offered in a form standardized on both steroidal saponins and pregnane glycosides. Hoodia gordonii is becoming so popular as a weight loss product that its export is being monitored by the South African government. It has become so endangered that, since 2005, only hoodia grown on commercial farms is permitted an export license, and exporters must obtain a license from the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES). Importers also require a permit from the US department of Agriculture, and a CITES certificate is also needed to re-export the finished product. Because of this, more hoodia weight loss pills are being sold than there is hoodia gordonii to produce them. It is not uncommon for cacti such as the prickly pear cactus from Mexico, to be used, or for low concentrations of hoodia to be bulked up with fillers. Neither of these is of any use as an appetite suppressant, the former having no active ingredients whatsoever and the latter containing only traces. If you are purchasing hoodia, therefore, be aware of this. Request sight of the CITES certificate and USDA permit, and also the analysis results by an authorized laboratory to confirm that the product is what it purports to be. Otherwise, there is some evidence that Hoodia gordonii can help you reduce weight, although to date there are only four recognized analytical laboratories registered to analyze the active content of hoodia weight loss products. Finally, check for the analysis certificates. All Hoodia weight loss products should be analyzed by each of three methods: Microscopy, High Performance Thin Layer Chromatography (HPTLC) and High Performance Liquid Chromatography (HPLC) - all there are needed. The four authorized laboratories are: the University of Mississippi, Chromadex labs in Irvine California, Alkemist Pharmaceuticals and Advanced Laboratories, Smithfield, NC. No others will do, so if your Hoodia weight loss preparation has not been analyzed using the three methods by one of these laboratories, don't buy it, even if it can show the CITES and USDA documentation.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1946) Vitamin B Complex
Date:
November 24, 2008 04:45 PM
The connection between B vitamin complex and stress is well known; although why a good B vitamin complex can reduce stress is less well known. Before discussing the reason why a Vitamin B formula can reduce stress, we shall first have a look at stress and what causes it. The term means different things to different people, and a stressful situation to one person might not be such to another. The biochemistry of stress is fairly complex, although involves the production and release of hormones into your bloodstream. When an event occurs that causes stress, the hypothalamus portion of your brain becomes involved. It releases cotocotropin releasing factor (CRF), a hormone that protects you from stress by raising your spirits. CRF sends signals to the pituitary gland causing the release of ACHT (Adrenocorticotropic hormone corticotropin) that causes cortisol to be released into the bloodstream by the adrenal glands. Cortisol speeds up the metabolism. Coincidentally, the cells of the brain stem and spinal cord send a message that stimulates the adrenal glands to secrete epinephrine that increases the heart rate, breathing and alertness, ready for fight or flight. Both of these mechanisms then lead back to the pituitary gland and your new stress level can repeat the process or stop it, should your stress be reduced. If this cycle continues over an extended period of time it can have serious repercussions on your mental and physical health. The B vitamins can help to regulate this biochemical function, and in doing so can reduce stress, and with it the associated anxiety and depression. In fact many of the symptoms of vitamin B deficiency are those that are also associated with stress: anxiety, nervousness, depression irritability and so on. There is no one specific form of Vitamin B that helps with stress, and there are eight in total. However, in saying that, the three members of the B vitamin complex that have most effect on stress are vitamins B 3, 6 and 12. Every one of the B vitamins is involved in cell metabolism. Because they are soluble in water, they are quickly leached from the body so have to be replaced on a regular basis. The various B vitamins are needed by your body for specific purposes, such as Vitamin B1 (thiamin) is essential for the correct function of your nerves, brain and muscles. Although others have their own particular areas of responsibility, they are generally lumped together, not only because they are all soluble in water, but also because they each have a profound effect on the metabolism of your body. Those mostly connected with the nervous system are Vitamins B3, B6 and B12. Vitamin B3 (Niacin) helps to maintain the proper health of your digestive system, skin and nerves, and B12 (cobalamin) is also needed for a healthy nervous system. Vitamin B6 (pyridoxine) along with vitamin B12 are the two principal members of the B complex that have an effect on stress, and a deficiency of these can make you more prone to this frequently debilitating condition. In fact many people that are suffering from a general Vitamin B deficiency have various forms of mental problems. Because Vitamin B12 is available only from animal sources, deficiencies are common in vegetarians, and even more common in vegans who are advised to take a Vitamin B12 supplement. However, in general you are best to take a Vitamin B complex as opposed to a supplement of any specific member of the B family. This is because a surplus of any one could lead to a depletion of others. It is thought that much of today's stress is caused by an inadequate diet, and a diet deficient in various forms of Vitamin B is believed to render the subject particularly prone to stress and anxiety. People that have been suffering undue levels of stress over a protracted period of time can be helped by a regular treatment of B vitamins. In taking such supplements, however, you should also be aware of the various possible effects on your body that the causes of your stress can have. These are frequently neither understood nor recognized when they occur. For example, if you are under stress due to a poor diet, or conversely, are eating a poor diet due to your high stress levels, you might be building up fatty deposits in your liver. Because of this your general health could be at serious risk in addition to your mental health. It is important, therefore, that you don't just restrict yourself to a B vitamin complex, but also take a supplement containing inositol and choline bitartrate. These can reduce the fatty deposit that a poor diet can cause to build up in your liver with consequent risk to life. Such deposits affect the ability of your liver to destroy the environmental toxins to which become exposed as part of your daily life, and which can be directly related to your ability to counter high stress levels. In general, however, if you are prone to stress and get nervous and worried about the slightest thing that doesn't go to plan, a B vitamin complex can help: vitamin B can reduce stress, although if your stress is sever you would be better advised consulting a physician than a health store. Stress is a serious condition, and not one that should be treated lightly. It is possible to treat some stress conditions by using a good B vitamin complex, although should the stress be serious then you should consult your physician. Frequently the stress is not diet related, but due to personal circumstances that cannot be cured by any form of supplement. However, there are few doubts that a course of Vitamin B supplements can help to overcome many of the metabolic causes of stress, and make up for any deficiency in these vitamins that leave your body almost as quickly as they enter it. Vitamin B can reduce stress, but only if your stress is due to a deficiency: and this is more common that most people are aware.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1938) Hoodia Extract And Appetite
Date:
September 26, 2008 11:36 AM
Hoodia is a plant that belongs to the milkweed family and consists of about twenty different species. It is a leafless, spiny plant, with fleshy finger-like stems. Along the stems, there are rows of thorns, while the plant bears flesh-colored flowers. Flies are attracted to the flowers by the strong smell of decaying meat, causing the flies to lay their eggs and pollinate the flowers. Sometimes spelled hootia, hodia, hoodie, and hudia, hoodia has recently gained a great amount of attention in the United Kingdom and America after being featured on BCC and CBS. Often growing in summer rainfall areas in Angola, Botswana, Namibia, and South Africa, along with winter rainfall areas in Nambia, hoodia gordonii is the only species that contains the chemical component that suppresses appetite. Hoodia has been used for thousands of years by San Bushmen, as it populates the arid territories of South Africa and Namibia. Because San Bushmen needed to remain active in order to survive, they had little need for dieting, but this plant provided them with stamina and a curbed appetite during long periods without food. Along with reducing or eliminating the desire for food, many people believe that hoodia also increases energy and can act as an aphrodisiac on the user. The appetite-suppressing ingredient found in hoodia is a molecule that is similar to, but stronger than glucose. The active compound that was isolated to be responsible for appetite suppression is P57, which works by sending a signal to the hypothalamus of the brain, tricking the body into thinking that it is no longer hungry, and resulting in a complete lack of appetite. P57 is a steroid like molecule that is chemically bonded to a chain of three sugar molecules. The appetite-suppressing and mood-enhancing properties of P57 go directly to the mid-brain, where it causes neuron cells to fire as if you were full. The hypothalamus is the region of the brain that contains several important centers which control body temperature, thirst, hunger, water balance, and sexual function. Additionally, the hypothalamus is closely connected with emotional activity and sleep and also functions as a center for the integration of hormonal and autonomic nervous activity through the control of pituitary secretions. In short, the hypothalamus links the nervous system to the endocrine system. The pituitary gland is often thought of as the mater gland in our bodies, as the anterior and posterior pituitary secrete a variety of hormones that influence all cells and affect almost all physiological processes. The pituitary gland is powered by the hypothalamus, as some of the neurons in the hypothalamus secrete the hormones that are responsible for controlling the secretion of hormones from the anterior pituitary. The inhibiting and releasing hormones of the hypothalamus are carried directly to the anterior pituitary where hypothalamic hormones bind to receptors on anterior pituitary cells.
The P57 hormone that is found in hoodia works by increasing the amount of ATP in nerve cells found in the hypothalamus. ATP is an energy-producing molecule that is formed from glucose. When there are increased levels of ATP in hypothalamic nerve cells, those nerve cells fire as if you had just eaten, even when you haven’t. Hoodia is a safe herb taken for hundreds of years, have you tried Hoodia lately?
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1900) Panax Ginseng
Date:
September 22, 2008 09:48 AM
Panax is a type of perennial plant with fleshy roots, and grows in Eastern Asia. Ginsengs contain ginsenosides that are triterpene saponins, steroidal compounds that are found only in Panax ginseng. The effects of these saponins are difficult to establish, but they are believed to be behind the properties of ginseng. Panax ginseng is found predominantly in Korea, China and Siberia, although a genus has also been found in Vietnam. Panax are adaptogenic herbs that help promote resistance to anxiety, fatigue and stress, and are said to adapt the body to resist a number of different stressors. It has been proposed that adaptogenic herbs can balance the endocrine hormones of the hypothalamus, pituitary and adrenal axis. They also normalize the immune system, and increase the activity of phagocytes, the killer cells. Additionally, they not only help to maintain homeostasis, but are believed to go further and act as allostatic agents, adapting response to maintain system stability in a more dynamic fashion, by changing interactive functions as opposed to the individual adaption’s made in homeostasis. Not all ginsengs are the same, and although Siberian ginseng is an adaptogen, it is not a true ginseng. Its roots are woody rather than fleshy, and it contains eleutherosides as opposed to ginsenosides. These also are triterpenoid saponins, but of a different adaptogen. The herb is actually Eleutherococcus senticosus as opposed to Panax ginseng and P. quinquefolius, both true ginsengs. Siberian ginseng was misnamed as a marketing ploy. American ginseng is Panax quinquefolius, sometimes referred to by the Chinese as Huaqishen. It, too, is an adaptogen and a true ginseng, containing ginsenosides. However, it contains much less ginsenonide Rg1 than panax. This ginsenonide appears to possess estrogen-like activity and improves spatial learning. The other forms of ginesonide found in panax ginseng are: Ginsenoside Rb1: This appears in greatest concentration in American ginseng, and appears to have an effect on the reproductive system. It not only has an effect on the testicles, but is believed to increase testosterone production through its stimulating effect on luteinizing hormone. It also helps to rdeduce the incidence of angiogenesis, which is the formation of new blood vessels from old, and also a stage in the development of malignant tumors from dormant ones. Ginsenoside Rc: this possesses sedative properties, and in a study on breast cancer was found to have an effect in inhibiting the growth of these particular cancer cells. Ginsenoside Rc might therefore have use in the treatment or prevention of breast cancer. Studies have also suggested that this ginsenoside could increase the motility of sperm: the motiliy of sperm was found to increase significantly in a solution of ginsenoside Rc. Ginsenoside Rf: this is present only in panax ginseng, and studies have indicate that it has an inhibitory effect on the Ca2+ neural channels in the brain, and so cokld have an analgesic effect. Studies have as yet failed to explain this effect that is seen in animal tests, but are continuing on this ginsenoside. Ginsenoside Re: this ginsenoside has strong antioxidant effects and has a significant antidiabetic effect in that is reduces insulin resistance, which is likely why ginseng is taken to treat Type 2 diabetes. Studies are ongoing into the properties of this ginsenoside, and also on the other 10 or more that are known to be present in Panax ginseng. The effects of ginseng are difficult to establish with certainity because they work through so many different pathways and it is difficult to isolate one. More than one ginsenoside, for example, affects the calcium channels in the brain, and it is difficult to determine which does what. There are fewer ginsenosides in Panax quinquefoilius, and in the USA it is only the panax version that can be traded as simply ‘ginseng’. One of the main problems with all ginsengs is that although it is one of the most studied plants, the majority of the studies have been on animals, and due to this, and the difficulties caused by the multiple pathways described earlier, many of the postulations have not been proved in humans. However, if the theory as it is know today is taken into consideration along with the traditional uses of ginseng in traditional Indian (ayurvedic), Chinese and Native American medicine, it would be fairly accurate to say that ginseng is useful in helping your body to recover after illness or surgery, and to help you to deal with stress. It has also been proved to lower your blood glucose (sugar) levels, and help in the treatment of Type II diabetes, as already mentioned. There is evidence that it helps to boost your mental performance, memory and might help to slow down the onset of Alzheimer’s disease. Ginseng can also give a boost to your energy levels, and it is genarally accepted that panax ginseng is more effective than the American version. In traditional medicine, Asian ginseng is said to be warming, and the American variery cooling. Thus Panax ginseng is useful for people recovering from illness and trying to recover their strength, acts as a tonic, stimulant and supports the immune system. In other words it helps the body to get whole again after being depleted. It should not be used if you get very hot and red, such as with heat stroke, unless you use it in combination with the American version, because these are conditions of high yang and this type of ginseng will increase the yang even further. American ginseng, on the other hand, is good for those with fevers, hypertension (high blood pressure), and suffereing the effcts of heat. It helps build the yin and reduce the yang, so if you always feel flushed and hot or are hyperactive then go for the American, and if you easily get chilled or find your hands and feet get cold very easily, reach for the Asian ginseng to increase your yang. You often find ginseng as an ingredient in soft drinks, but the concentration is so low that it has no metabolic or pharmacological effect. The dose to be taken should be as stated on the pack, since there is no specific standardization. It has been noted that the effects can be lost if an excess of ginseng is taken, but generally the herb is safe and if you feel a bit down or lacking in energy, ginseng can work wonders for you.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1895) Gamma Oryzanol
Date:
August 29, 2008 09:20 AM
Gamma Oryzanol is extracted from rice bran oil, and is a mixture of substances that includes ferulic acid and sterols. It is not restricted to rice barn oil, and is also found in the bran of other grains, and some fruits and vegetables. It is commonly used as a sports supplement, although possesses other uses including treatment of menopausal symptoms and high cholesterol levels. Athletes use gamma oryzanol to increase their muscle bulk through it increasing the levels of testosterone and other anabolic hormones. Although there is little scientific evidence for these effects, bodybuilders claim excellent results and the other benefits that the substance offers make it worthwhile taking. The reported benefits are so common and widespread that they are difficult to ignore, and it can be assumed that, in the absence of scientific evidence through test results, the athletes and bodybuilders are right until proven wrong. Gamma oryzanol is reported to promote a number of metabolic effects on the body such stimulation of the Human Growth Hormone that is involved in increasing muscle bulk. It also induces increased release of endorphins, and improves recovery after exercise. Ferulic acid promotes increased strength, reduced fatigue and improved recovery. The catabolic effect of cortisol is also reduced. Cortisol is produced during exercise and it is destructive to muscle tissue. What this does in practice is to increase your recovery time, and after a long run it can take two days to recover and allow your exercise effectively again. It is important that your body is conditioned to rapidly reduce its cortisol content after exercise, and ferulic acid helps you to do this. Athletes have reported no side effects from doses of up to 900 mg of gamma oryzanol and 60 mg ferulic acid, which appears to be up to thirty times as bioavailable to the human body as gamma oryzanol. However, there are many more uses of the supplement than just metabolic ones. Gamma oryzanol possesses strong antioxidant properties. Ferulic acid is a phenolic phytochemical, and a derivative of trans-cinnamic acid. As such, it is an antioxidant with strong reducing properties towards free radicals. Free radicals are implicated in cardiac problems cause by the oxidation of LDL cholesterol, leading to atherosclerosis that is responsible for strokes and blockages of the cardiac arteries. Lipid peroxides can be formed by the oxidization of fats, and can damage nerve cells and muscle tissue. Antioxidants can also lead to premature aging through the destruction of human body cells, damage to DNA and also many forms of cancer. Although it is believed that components of gamma oryzanol can inhibit the initiation of some cancers, the evidence is still scanty and the research in its infancy. Any substance that destroys free radicals is of benefit to your health, and Ferulic acid stands beside other strong antioxidants such as Vitamins A, D and E, and many of the high colored phytochemicals such as beta carotene. It is believed to have anti-cancer properties with some forms of cancer, such as breast and liver cancer, though, as referred to above, studies are continuing. Paradoxically, intensive physical exercise can lead to the generation of more free radicals, since they are a by-product of the generation of energy in the mitochondria from blood glucose, and so, in addition to its beneficial metabolic and anti-catabolic properties, gamma oryzanol should be taken during exercise in order to reduce the effect of these dangerous molecules. The effect of gamma oryzanol on cholesterol levels has been demonstrated, and complement the same effect offered by the fatty acid component of the bran oil. It appears to prevent the absorption of cholesterol by the digestive tract, and so allow it to be excreted naturally before doing any harm. It is believed that the phytosterols present in rice bran oil block the cholesterol absorption sites in the intestine, so is must continue down the intestinal canal until it is evacuated. Cholesterol itself is essential to human metabolism and biochemistry, and without it we could not survive. Cholesterol is not soluble in water, and it has to be bound to low density lipids (LDL) to enable it to be transported round the blood to where it is needed: usually in the arteries to heal up arterial damage, a bit like a sticking plaster. However, free radicals oxidize these LDLs and deposit them along with their cholesterol on the artery walls: that is the problem, not the cholesterol itself, and is why antioxidants such as gamma oryzanol are so important to us. Rice bran oil has been used by the Japanese for many years to treat elevated cholesterol levels and also to reduce high triglyceride levels. It also acts as an anti-inflammatory, specifically in the stomach and can be used to treat gastritis, in that it reduces the inflammation of the stomach lining. There is some evidence from studies on animals that the substance could be effective in treating gastric ulcers, although the results with animals have not yet been tried on human subjects. Another mechanism, other than the anti-inflammatory route, is through the normalization of the secretion of the gastric juices. Another use to which gamma oryzanol has been successful put is in the treatment of menopause symptoms. This is another of those situations where some trials have proved unsuccessful, but those that use it has found it be effective. Hot flashes and aging syndromes are two symptoms that have been effectively treated by use of the supplement, with one study reporting a 50% reduction in symptoms in 70% of patients. The way this is theorized to work is through the inhibition of the secretion of leutinizing hormone by the pituitary gland, which promotes the hypothalamus to release endorphins. Endorphins help to overcome the effects of the menopause.
Gamma oryzanol, then, has found use by many athletes and bodybuilders in its metabolic properties in helping to increase muscle bulk and reduce fat, and by shortening recovery times by reducing the catabolic effect of cortisol. However, apart from these sports-related benefits, it possess antioxidant and anti-inflammatory properties that are beneficial to your general health.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1877) Garcinia Cambogia
Date:
August 28, 2008 09:33 AM
Garcinia Cambogia is found naturally in India and parts of Asia, and also on the Pacific coast of South and Central America all the way from Peru up to Mexico, and likes a humid forested environment. Also known as Brindall berries, garcinia is believed to act as an appetite suppressant and allows you to lose weight by diminishing your desire for food. The Malabar tamarind, as it is also known, is about the size of an orange resembling a small pumpkin, and an extract from the fruit and rind is used in several weight loss products. The health risks presented by synthetic diet pills render a natural product extremely attractive were it to be effective. So can Garcia curb your appetite? What is the scientific evidence for it, and what biochemical route would it take? Although tests on animals have been very positive, human results have been inconsistent. In some double blind tests using a placebo, weight loss was up to three times that of the control, but in others there was no apparent difference between those taking garcinia, and those given a placebo. However, doubts have been raised of the validity of some of the negative tests, so what does science tell us? The active ingredient in the cambogia extract is hydroxycitric acid (HCA), which is a powerful inhibitor of ATP citrate lyase, an enzyme that catalyzes the reaction between citrate and Coenzyme A to Acetyl CoA and oxaloacetate. Since the acetyl CoA is necessary in the synthesis of fatty acids and lipogenesis (the conversion of glucose to fatty acids), then anything that inhibits the biosynthesis of acetyl CoA must help to reduce the amount of fat stored in your body. By inhibiting this reaction, that occurs outside the mitochondria so is not a direct part of the Citric Acid Cycle, HCA should theoretically suppress the formation of fats from carbohydrates, reduce food intake and thereby induce weight loss. But that is not the only mechanism. A study at Georgetown University in Washington found that after 8 weeks of taking the garcinia extract, there was a 5.4% reduction in body weight and body mass index, and a significant reduction in low density lipoproteins (LDL) and triglycerides with an associated rise in high density lipoproteins (HDL). This is good news for those suffering from high cholesterol levels, since the LDL lipoproteins are those that carry cholesterol to the major blood vessels, and which when oxidized by free radicals deposit fatty plaques on the artery walls. These plaques constrict the arteries and the resultant atherosclerosis can lead to cardiac problems and strokes. HDL lipoproteins carry cholesterol back to the liver for destruction, and is known popularly as ‘good cholesterol’. The studies also indicated modifications to certain indicators of the status of fat deposits in the body and of appetite modifiers in the brain. In this respect they found 38% decreases in serum leptin and increases in serotonin levels of 44%, and the excretion of fat metabolites in the urine increased from between 32% and 104%. These are significant findings, and further research has indicated that HCA helps to suppress appetite. Serum leptin is an indicator of the level of fat stores in the body, and as the leptin levels in the blood reduces, the hypothalamus is given an instruction to increase the appetite so as to increase the fat levels again. However, it is believed that HCA possesses leptin-like properties, and this signal is either not generated or is modulated. The increase in serotonin has the same effect. It is known that serotonin controls the appetite, although the exact mechanism has not yet been established. What is known is that serotonin activates certain neurons and melanocortin-4 receptors (MC4R) in the brain, that not only curb appetite but also block the effect of other neurons that would normally increase appetite by blocking the effect of MC4Rs. This is how the banned anti-obesity and serotonin inciting drug Fen-Phen operated, and it appears that the hydroxycitric acid in garcinia cambogia extract acts in a similar, but safer, way. The problem with drugs such as Feb-Phen was that they created cardiac problems which could be dangerous to obese people whose hearts might have been weakened. However, now that the biological pathway by which serotonin controls weight is believed to be known, if not fully understood, the way is becoming clearer as to how safer weight loss pills, acting through appetite suppression, might be developed. It also provides a valid scientific explanation for the effect of garcinia cambogia extract which might in itself prove to be that safer way. The biochemistry supports the evidence of its effect on those wanting to lose weight, and also bolsters the claims that those tests and trials found to be negative were in some way flawed. Until the full chemical pathway is understood, the factors that can lead to flawed tests are unknown, although one could be the use of excessive fiber in some trials that could reduce the effect of the extract. One of the effects of HCA is to limit the ability of your body to convert carbohydrates into fat (the Acetyl CoA inhibition mentioned above). That, combined with suppression of your appetite and a higher rate of thermogenesis, prevents the body from storing excess carbohydrates as fat. Instead you will have increased energy levels, so you should exercise to use this up while taking garcinia extract. For this reason it is popular with athletes and bodybuilders seeking an energy source that has not yet been banned from sport. Although diet pills based on the same principle had side-effects and could make the user feel on edge, there are none known with garcinia. However, it is possible to reduce the absorption of some essential nutrients due to appetite suppression, so do not exceed the recommended dose. An excessive amount can also led to gastric discomfort, but none of these effects have been noted when the recommended doses have been adhered to.
However, if you are diabetic, pregnant or a nursing mother, you should consult with your physician or health professional before taking the extract. Garcinia Cambogia presents no specific risk to such people, and this warning should be given for all non-prescriptive treatments that your physician might be unaware of you taking.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1876) GABA
Date:
August 26, 2008 04:58 PM
GABA is gama amino butyric acid, and is an inhibitory neurotransmitter that is essential for the proper function of your brain and the central nervous system, and has the effect of reducing excessive brain activity and promoting a state of calm. For many people, the rush of daily life, with its problems, worries and external stimuli, can over-stimulate the brain to the extent that it can all seem too much for them. They feel anxious and overwhelmed, and wish that they could just go into a quiet corner to get away from it all. Most people have felt like that at some time, but the demands of life do not allow them that luxury. They just have to bear it and get on with life. That is where GABA can come in. It can be used to bring your nervous system back to base, and make you feel more relaxed, calmer and more able to meet these challenges that life often throws at you. When you feel that you just can’t relax or concentrate on what you are doing, GABA can help you. If you look around you and everybody else seems OK, without apparently feeling the stress and irritability that you feel, and then perhaps your problem is due to a GABA deficiency. GABA is the principal inhibitory neurotransmitter in your brain, and a deficiency would certainly give you the symptoms that you are feeling. Let me explain why. As your brain becomes excited, it can run out of control and needs some form of modification or inhibition to keep it acting as normal. Without this you would become increasingly more restless and irritable, and ultimately have seizures. GABA is not only the main inhibitor in your brain, but also helps in the production of endorphins that provide you with a sense of well being. That sense of calm you feel when endorphins are produced, for example during exercise or sexual intercourse, is commonly referred to as the ‘endorphin effect’. GABA is at its highest concentration in specific areas of the brain, including the hypothalamus, the hippocampus and the central brain area, and is present in up to 40% of all synapses, the small gaps between neurons across which brain cells can communicate with each other. It is produced during the Krebs or Citric Acid Cycle that is responsible for cell respiration or the production of energy from carbohydrates. It is synthesized from alpha-keto glutarate, which is produced just before the Succinyl Co-A stage of the Krebs Cycle in the brain. Vitamin B6 in involved in its metabolism, and a Vitamin B6 deficiency can lead to a deficiency in GABA that might result in seizures. Basically GABA works by inhibiting the firing of neurons in your brain, and thus reducing general brain activity. The GABA receptor allows more chloride ion to enter the brain cell, thus helping to maintain the electrical charge within the cells. Bezodiazepines (e.g. diazepam) work by increasing the effectiveness of GABA in opening the chloride ion cells to allow more chloride ion to enter the neurons, and caffeine does the opposite, and inhibits this property of GABA. Thus diazepam works as a minor tranquilizer and caffeine as a stimulant. Alcohol has a similar effect to the benzodiazepines, increasing the release of chloride into the neurons, and is the major way in which alcohol affects the brain. In fact, tolerance to drugs and withdrawal symptoms can be explained by the receptors adapting to the drug. They may increase in number, which means that more of the drug is needed to work on them, and they can become hypoactive in the event of the drug being withdrawn, that enhances the symptoms that the drug was intended to treat. So basically, that is the way that GABA works. In simple terms it increases the flow of chloride electrolyte to the brain, and in so doing affects our mood. This effect is enhanced by prescription drugs such as Valium and Ativan, which are used by those that suffer the effects of a GABA deficiency. However, these drugs have side effects, not the least of which is dependency due to the GABA receptors becoming modified to suit the drug. There is a more natural way to overcome many stress problems and symptoms of mood swings. Knowing what causes these symptoms, it makes sense to eat foods that stimulate the creation of neurotransmitters to replace those that are deficient. Since GABA is produced in the Krebs Cycle and complex carbohydrates produce glutamine that is an important part of that Cycle, and is also the precursor to GABA, then the consumption of such foods should in theory produce more GABA. In this case the theory works, and you should eat foods rich in complex carbohydrates such as whole grains, brown rice and oats as part of your diet. Other foods that are high in glutamine or its precursors, glutamic acid and glutamate, include citrus fruits, beef liver, broccoli, halibut and lentils. A useful supplement to take is L-theanine, an amino acid found in green tea, and available in supplement form. L-theanine can calm your nerves while maintaining clarity of thought. In other words it calms you down, but doesn’t make you drowsy and allows you to enjoy your day with anxiety. Your doctor can determine whether or not you have a neurotransmitter deficiency through a simple urine test, and might also test your saliva for hormone content. A GABA supplement might be indicated, and if so it other beneficial effects on your body other than its effect on your brain cells. It improves your sleep cycles and promotes vivid dreaming, and can also have a positive effect on your blood pressure. It is also an effective pain killer, and can provide relief from such conditions as back pain and arthritis. Its stimulating effect on the anterior pituitary gland to secrete Human Growth Hormone might also be regarded as a benefit by many. Increasing the level of HGH in your blood can lead to fat loss and improved anabolic activity (increase in muscle tissue). This can be of benefit to older people whose level of HGH secretion has dropped off, and who find it more difficult to lose fat. GABA is a substance that has many known benefits and no known side effects other than a slight tingling and increase in heart rate when the supplement is first used. It has a definite benefit for people to whom the world seems too hectic and overwhelming.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1875) Garcinia Cambogia
Date:
July 08, 2008 03:00 PM
Garcinia cambogia is a small tree bearing a small pumpkin-like fruit of the citrus family, and is steadily appearing in an increasing number of weight loss supplements. It is indigenous to parts of Africa and Asia, and the rind is commonly used in Indian cookery. Although the fruit is particularly sour to the taste, it is used in form of an extract of the rind and claimed to act as an appetite suppressant and also to increase the body’s capacity to metabolize fat. Although there are conflicting claims being made about its efficacy, or lack of it, research shows that it definitely has promise as an agent to prevent and fight obesity and its use is steadily increasing in this respect. The active ingredient is hydroxy citric acid, otherwise known as HCA, contained in the form of the potassium and calcium salts of the acid in the aqueous extract of the garcinia cambogia rind. It forms up to 30% by weight of the rind. It is tasteless and odorless, and so far found to have no toxic effects on humans. Animal studies have also been generally favorable. HCA works in two specific ways both to reduce the desire to eat and to inhibit the storage of fat in the body. In each case, as with so many supplements that have an inhibitory effect on a physiological or psychological function or on a metabolic process, it involves an interaction with enzymes. Citrate lysase is an enzyme in the body that helps to prevent lipogenesis and instead promotes the conversion of carbohydrates into fat. When this enzyme is inhibited from carrying out its intended part in the body’s metabolism, the process of carbohydrate oxidation is boosted, or, in other words, the excess carbohydrate is burned off, or changed into energy. More fats could also be expelled unchanged from the body, but irrespective of that the end result is that less carbohydrate tends to be converted to fat. Garcinia cambogia, however, has not been found to reduce the body’s uptake of essential fatty acids which are necessary for health. Had this occurred, you would feel a raging hunger as opposed to the appetite suppressing properties the extract is claimed to have. The oxidation of carbohydrates can also lead to thermogenesis, or the boosting of the metabolism by increasing your body temperature. An increase in the metabolic rate helps weight reduction through an increased calorie demand while your body is at rest. However, that is not the only way in which the HCA extract works to help reduce your weight, or at least help to maintain it at a healthy level. Let’s return to its specific appetite suppression properties. Serotonin (5-hydroxytryptamine) is a neuroreceptor found in the central nervous system. It has many regulatory effects on the body, one of which is appetite. Although it is by no means the only chemical in the body that has an effect on the appetite, serotonin is a significant factor. As you get hungry, serotonin is released in the hypothalamus, an area of the brain that regulates sleep and eating. The release of serotonin increases when you see and or smell food. It is the agent that starts canine salivation, and a ravenous hunger in those that have no immediate access to food. It also causes you to snack, and, as you eat, the serotonin level in the hypothalamus continues to increase until it reaches a point where it provides the hypothalamus with a feeling of repletion or satisfaction. You then stop eating. So the more serotonin is produced, the quicker you stop feeling hungry. Garcinia cambogia extract has the effect of stimulating the emission of serotonin into the hypothalamus, and so suppresses your hunger quicker. You don’t stop eating altogether, but attain that feeling of satisfaction much quicker and so tend to eat less with each meal. This can not only help you maintain your weight at a healthy level, but also to reduce weight in the obese. Although the extract can work through each of these mechanisms, it does not have such a significant effect on a very fatty diet. It can help if you switch to a relatively healthy diet, lower in fats, but the effect might not be strong enough to compensate for a poor diet in terms of fat content. Studies have indicated an anti-oxidant activity that likely comes from the xanthones and xanthone derivatives that are also contained in the fruit. In fact there are other recorded uses of garcinia cambogia, and it has been used in traditional Indian medicine to treat fevers, dysentery, open wounds, ulcers and tumors. According to a study carried out for the National Cancer Institute there is no documented toxicity effects on humans, and there is no regulation regarding the use of garcinia cambogia. It has not been evaluated by the FDA. However, there are contra-indications in the case of pregnant and lactating women, more as a safety measure than for any particularly known risk. Alzheimer patients should avoid taking HCA since there is a possibility of it promoting the synthesis of acetylcholine in the brain, and its glycemic action renders it unsuitable for diabetics. Conversely, this same action is a positive benefit by reducing the craving of healthy adults for sweet foods. However, HCA is frequently taken in combination with chromium due to the latter’s positive effect on the regulation of blood sugar levels. Nevertheless, diabetics should avoid any supplement containing chromium without professional medical advice. The supplement should be standardized on the HCA content, and an average dose is around 500 mg – 1000 mg of 50% extract a day. However, this varies, and the most important aspect of such extracts is that when changing brands; be sure to compare the strength of the relative extracts and change your dosage accordingly.
Although the benefits of garcinia cambogia to those seeking to lose weight are debated, there is ample evidence to suggest that a regular intake of the extract is beneficial – and not only with respect to the maintenance of healthy weight.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1833) Fat Controls our hunger centers in the brain!
Date:
April 04, 2008 11:28 AM
The main cause of any chronic disease of aging including Type II diabetes, CV disease, obesity, osteoporosis, and cancer are all caused by miss communication between signals that tell your body how to turn energy into life and the brain. The two most important signals that we know of today are given by the hormones insulin and leptin. Leptin is an extremely powerful and influential hormone that is produced by fat cells. It has totally changed the way scientific researchers look at fat, nutrition, and metabolism in general. Before leptin’s discovery in 1994, fat was regarded as strictly an ugly energy store that most everyone was trying to get rid of. However, after it was discovered that leptin is actually produced by fat, fat became an endocrine organ similar to the ovaries, pancreas, and pituitary, as it influences the rest of the body, especially the brain. Leptin is the most powerful regulator known to date of eating and reproduction. Your fat tells your brain whether you should be hungry or eat and make more fat, whether you should reproduce and make babies, or whether to maintain and repair yourself. It can then be stated that instead of your brain being in control of your body, your body, especially its fat and leptin, controls your brain. Throughout history, it has been in ones best interest to store some fat to call upon during times of famine. However, it is also just as bad to be too fat. For most of our history, it was necessary to run, hunt, and avoid being prey. Therefore, fat storage had to be highly regulated and it still is. When a person typically tries to lose weight, the body tries to gain it back, resulting in what is commonly known as yo-yo dieting. Because of this, it has long been theorized that there is a “set point” and there must be a hormone that determines this. Science now believes that leptin is that hormone. So in order to break the yo-yo cycle, one must control leptin. If a person is getting too fat, the extra fat produces more leptin that is suppose to tell the brain there is too much fat stored and the excess should be burned. Signals are then sent to the hypothalamus to stop being hungry, stop eating, stop storing fat, and start burning off some extra fat. Controlling hunger is a major way that leptin controls energy storage. Hunger is a very powerful drive that will make you do all you can to eat if it is stimulated long enough. The only way to eat less in the long-term is to not be hungry and the only way to do this is to control the hormones that regulate hunger. The primary hormone that does this is leptin. It has recently been found that leptin not only changes brain chemistry, but can also rewire the neurons in areas of the brain that control hunger and metabolism to do its bidding. The inability of the body to hear leptin’s signals plays significant and even primary roles in heart disease, obesity, diabetes, osteoporosis, autoimmune diseases, reproductive disorders, cancer, and even the rate of aging itself. In a process called glycation, glucose reacts with protein which results in sticky, sugar-damaged proteins called advanced glycated end products, or AGEs for short. When protein is damaged, it can’t function or communicate properly. AGEs promote excessive inflammation and free radical damage. AGEs and free radicals from oxidation are two of the major molecular mechanisms that cause damage which leads to aging. AGEs cause skin and the lining of arteries to wrinkle and inflame, which contributes to plaque and heart attacks. They can also promote the formation of cataracts and macular degeneration leading eventually to blindness. The glycation process has also been connected with the destruction of proteins and nerve cells that may lead to Alzheimer’s disease, memory loss, and a variety of neuropathies. Glycation and oxidation are two of the major molecular mechanisms where damage accrues, disease occurs, and death results. High blood sugar can suppress your immune system, making you more vulnerable to infection and cancer. Highly aggressive cancers outpace the availability of oxygen and therefore must use an anaerobic fuel, in the form of glucose. By consuming glucose (sugar), we feed cancer. Lastly, high blood levels of sugar form non-fiber carbohydrates and excess protein send leptin and insulin levels upward. If there is a known marker for long life, it is low insulin levels. Insulin’s purpose is not only to regulate blood sugar, but to store excess energy for future times of need. Insulin also lowers blood glucose levels as a side effect from storing it away, not regulating it. Today, high glucose is quite normal, as our insulin levels are typically much higher than they were among our ancestors. When you are constantly bombarding your cells with insulin, they become insulin resistant. This causes insulin levels to rise, creating a hormonal derangement that has a catastrophic effect on the metabolism. High insulin contributes to making you fat because it tells your cells to store nutrients as fat rather than to burn it. Repeated high levels of insulin cause insulin resistance. The more fat the body accumulates the more leptin the body can produce so fat works against to slow down insulin production causing insulin resistance.. High insulin causes the retention of sodium, fluid retention, excretion of magnesium, elevated blood pressure, cognitive heart failure, blood clotting, and arterial plaque formation. Heart attacks are much more likely to happen after a meal that is high in carbohydrates than after one that is high in fat. This triggers a stress response which can cause arterial spasm, constriction of arteries, elevated blood pressure, irregular heartbeat and sudden death. Insulin resistance along with low magnesium keeps you from metabolizing important fatty acids that are vital to your heart health in general. As critical as insulin is in your health, leptin may even be more so. Leptin plays a significant role in obesity, heart disease, osteoporosis, autoimmune diseases, inflammatory diseases, and cancer. But there are clues as to how to live a long and healthy life which brings us back to fat and leptin and our need to control it. One can control their insulin production and fat by dietary changes and blood sugar supplements.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1742) B Complex to Restore the Adrenal Glands from Stress
Date:
February 07, 2008 05:18 PM
The B vitamins comprise a range of water soluble vitamins that frequently work together to impart a number of general benefits to your body’s health. In general they support and maintain the metabolic rate, maintain the function of the nervous system, support the immune system, maintain healthy skin and muscles and help to promote cell growth and division. They work together to suppress the causes and symptoms of cardiovascular disease and stress and they are dispersed throughout the whole of the body by means of the circulation system of the blood. In very general terms they collectively ensure that the body is provided with energy from the metabolism of carbohydrates and glucose. They are also needed for the metabolism of fats and proteins, and also the maintenance and health of the nervous system in general. There are many natural sources, including lentils, potatoes, liver, turkey, brewer’s yeast, and also, of course, dietary supplements. Vitamin B Complex can help to restore the adrenal glands from stress, but to understand how it does so, it is first necessary to understand what these glands are, and the part that they can play in stress. The adrenal glands are situated just above each kidney, and take the form of two small pieces of tissue in the shape of a pyramid that generate specific hormones and chemical messengers. You have likely heard of adrenaline, the hormone that make you respond to certain types of stress either through flight or by fighting: what is known as the fight or flight reaction. Well, in fact there are two of them, noredrenaline being the other. They are also known as epinephrine and norepinephrine respectively. Both the adrenal glands are controlled by what is known as the HPA axis, short for the hypothalamus-pituitary-adrenal axis which is the stress center of the body. The adrenals are the main steroid-producing plants in the body, responsible not only for the adrenaline hormones, but also for cortisone and hydrocortisone, testosterone, estrogen, cholesterol, progesterone and a number of others. These are produced in the outer cortex of the adrenal glands, whereas adrenaline and noradrenaline are produced and secreted by the medulla. Adrenaline and cortisol are responsible along with others for the balance of your body fluids, blood sugar and blood pressure and many of the other main metabolic functions of the body, and if the adrenaline is not working properly, it can disrupt the metabolism of your blood glucose into energy, giving you a weak run-down and listless feeling. This is not surprising since your energy is failing at the cellular level. The main reason for adrenal fatigue is stress. Either emotional or physical stress or even poor nutrition can be responsible for reducing the functioning of the glands to such an extent that they no longer provide the steroid hormones in the proper balanced quantities needed to maintain the proper functioning of your metabolic processes. Unlike Addison’s disease, which a complete stoppage of the functioning of the adrenal glands, in Adrenal Fatigue Syndrome the glands still function, but at a reduced capacity and the various products they are responsible for generating are secreted in reduced and imbalanced quantities. However, fatigue is not normally the first reaction of the body to stress. As normal stress levels increase the bodies response is generally to secrete higher levels of adrenaline, and the cortex produces extra cortisol and other hormones. As stress continues beyond the intermittent stage and becomes more constant, the adrenals produce a more sustained high level of hormones, that generally raise blood pressure and also increase the level of sugar in the blood in order allow a sustained increase in energy levels. Corticosteroids are produced to maintain this higher level reaction to stress. Finally, when the adrenals can sustain this high level of activity no longer, adrenal fatigue sets in which is when the worst symptoms of the stress are evident: exhaustion, both physically and mentally, excessive fear, guilt and worry, and under-activity of the HPA axis leads to depression, hopelessness and severe illness, often due to a weakened immune system. So where does the B vitamin complex come into this? Vitamin B complex includes niacin, thiamine, pantothenic acid, riboflavin, and vitamins B6 and B12. As already stated, the complex is useful in supporting many of the critical functions of the body from healthy bones to healthy blood cells, and nervous systems. It also helps to maintain your reproductive system and can be used in cases of nerve-related conditions such as sciatica and neurological conditions. Pantothenic acid, vitamin B5, is particularly useful in dealing with stress in that it enhances the activity of the adrenal glands. It also increases your energy levels due to its effect on the Krebs Cycle through its action as a precursor of acetyl Coenzyme A and acetylcholine which is a primary neurotransmitter. This helps to reduce fatigue and the pain of headaches caused by excessive stress and consequent reduction in adrenal output. Pantothenic acid is also essential during the metabolism of proteins, fats and carbohydrates, and is important in the maintenance of healthy nerves, skin and glands. In fact the whole of the vitamin B family work together to make sure that your whole nervous system and metabolism remain healthy. People with high stress jobs often take the vitamin B complex to help reduce that stress and also anger. Excessive stress and anger can lead to anxiety and overwork the adrenal glands, and B complex can help to restore these to their normal function. If you are concerned about your adrenal health, you can have a simple test carried out on your saliva, blood or urine by a trained medical practitioner. Many doctors do not know to carry out this test since it is not a normal test as would be used to detect Addison’s Disease, or complete adrenal failure, but only adrenal fatigue, so ask specifically for an adrenal fatigue check. A quick self-test is to shine a light into an eye using a flashlight while looking in a mirror. They pupil should contract and return to normal after about 30 seconds. If it fails to do so, or even dilates, then that is a sign of adrenal fatigue. However, you must have it confirmed by a proper test. All in all, a B complex supplement is a good way to restore adrenal glands from stress, and it also helps your nervous system in general, in addition to aiding the metabolic processes of your body. However, make sure that your symptoms are what you think they are by seeking professional medical advice.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1713) Chronic Fatigue Syndrome and Fibromyalgia
Date:
February 28, 2007 12:02 PM
This is a fast paced world. We are all busy; living our full lives, burning the candle at both ends. We all get tired. We all get sick from time to time and maybe even depressed. But the illness called chronic fatigue syndrome is not like the normal ups and downs that we experience in everyday life. People with chronic fatigue syndrome feel overwhelming fatigue, and often pain as well. This is an illness that does not go away with a few good nights’ sleep. It drags on and on and doesn’t resolve itself. It steals vigor and energy over months, and sometimes even years. In this issue of Ask the Doctor, we will talk about powerful vitamins, minerals, amino acids, and herbs combined in scientifically validated formulas that people with chronic fatigue syndrome or fibromyalgia can use every day. These nutrients help address some root problems of chronic fatigue syndrome and fibromyalgia by restoring energy and health to sufferers. Q. What is chronic fatigue syndrome? A. Chronic fatigue syndrome (CFS) also known as chronic fatigue and immune dysfunction syndrome (CFIDS), or myalgic encephalomyelitis (ME), is a group of symptoms associated with unrelenting and debilitating fatigue. The profound weakness of CFS causes a persistent and substantial reduction in activity level. You feel too tired to do normal activities or are easily exhausted for no apparent reason. Besides extreme fatigue, symptoms of CFS include general pain, mental fogginess, flu-like symptoms, and gastrointestinal problems. A list of symptoms includes:
The number of symptoms and the severity of these symptoms can vary among people. The symptoms of CFS hand on or reoccur frequently for more than six months. Q. Are chronic fatigue syndrome and fibromyalgia considered being the same illness? A. Fibromyalgia syndrome (FMS) is a painful shortening of muscles throughout the body. FMS is basically a sleep disorder characterized by many tender knots in the muscles. These tender knots, called tender or trigger points, are a major cause of the achiness that people with fibromyalgia and CFS feel. Approximately 80 percent of chronic fatigue syndrome patients have received and overlapping diagnosis of fibromyalgia syndrome. For most people, fibromyalgia and chronic fatigue syndrome are the same illness. Q. What causes chronic fatigue syndrome? A. There are many causes that can trigger CFS. Current research is looking at the roles of neuroendocrine dysfunction, viruses, environmental toxins, genetic predisposition, food sensitivities, yeast overgrowth, faulty digestion, or a combination of these factors. For many people, CFS is triggered by a bout with a viral illness (like a cold or the flu), or even a stressful event. CFS is usually a mix of underlying causes. It is like a domino effect in that each problem can trigger another problem, and so on. For example, fatigue and poor sleep can trigger a weakened immune system, which can, in turn, trigger yeast or bacterial infections. Q. Who gets chronic fatigue syndrome? A. CFS is more common than you might expect. It strikes people of all ages, racial, ethnic, and socioeconomic groups. Approximately 800,000 people nationwide have CFS and over six million have fibromyalgia at any given time. It is important to stress that CFS is a real illness; it is not “just in your head.” Unfortunately, sufferers of CFS may find that many healthcare practitioners discount the symptoms of this illness or misdiagnose it as another disease. This can lead to additional emotional suffering. Q. How long does chronic fatigue syndrome last? A. The illness varies greatly in its duration. Some people recover after a year or two. More often, those who recover are more likely to do so three to five years after onset. Yet for some people, the illness seems to simply persist. There are rare cases of spontaneous improvement after five years without undergoing any treatment. However, this is very unusual. Q. What are the complications of chronic fatigue syndrome? A. The patterns of CFS vary from individual to individual. However, many common patterns of symptoms are seen in CFS sufferers. These symptoms and problems interact and create new symptoms and problems. For example, infections and disrupted sleep can lead to digestive, hormone, and immune problems. Infections The most notorious pattern seen in CFS is the one in which a person suddenly comes down with a flu-like illness that doesn’t go away. These viral or bacterial infections can suppress the body’s master gland, the hypothalamus. Since the hypothalamus controls the other glands, including the adrenals, ovaries, testes, and thyroid, suppression of this gland will lead to a subtle but debilitating decrease in the functioning of all glands and their hormones. Suppressed hypothalamic function from chronic infections can then trigger sleep dysfunction. Disrupted Sleep The suppression of the hypothalamus gland can lead to poor sleep because the body confuses its day/night cycles. Because of this, people with CFS have trouble staying in the deep, restorative stages of sleep that “recharge their batteries.” Poor sleep can cause immune suppression, which may lead to secondary bowel infections. The bowel infections seen in people with CFS can cause decreased absorption of nutrients, which can lead to chronic vitamin and mineral deficiencies. Q. Is there a cure for chronic fatigue syndrome? A. Treating chronic fatigue syndrome presents a significant challenge to people with CFS and their healthcare practitioners. Recently, a published placebo-controlled study ( of which I was the lead investigator) showed that when using an integrated treatment approach, over 85 percent of CFS and fibromyalgia patients can improve, often dramatically. The full text of this study can be seen at ‘www.endfatigue.com’. An editorial in the April 2002 issue of the Journal of the American Academy of Pain Management noted that this treatment, which I developed, is now a highly effective and excellent part of the standard of practice for treatment of fibromyalgia. Since this treatment addresses many different problems associated with CFS/FMS, it needs to be individualized to each patient. Medical Treatments Medications that provide symptom relief are frequently the first line of treatment chosen by healthcare practitioners for the person with CFS. These include medications for pain, sleep disturbances; digestive problems such as nausea, depression and anxiety, and flu-like symptoms. However, medications have not been universally successful because they tent to put a bandage on symptoms instead of addressing the root problems. Because of this, medications may need to be supplemented by the other supportive therapies that can address the root problems. Supportive Treatments People with CFS/FMS may be depressed, given the catastrophic lifestyle disruption these diseases may cause. They may also feel guilt and frustration because their symptoms were not taken seriously for such a long time. Fear can be a factor as employment and family relationships may be jeopardized by this illness. Therapies that help people to relax and improve coping skills may be helpful and include counseling for emotional and mental health, cognitive behavioral therapy, sleep management therapy, and massage. Daily Nutritional Supplementation for Energy Good overall nutrition is important for everyone, of course. However, there are several vitamins, minerals, and amino acids that can have powerful nutritional effects for a person with CFS. All of the vitamins and minerals in a chronic fatigue/fibromyalgia formula should work together synergistically to help improve energy levels and overall health. Here are some key nutrients to look for in an energy formula: Vitamins, Minerals & Other Key Ingredients Vitamin A: Essential for healthy skin and mucous membrane integrity, healthy immune system responses and healthy bone growth and healthy reproductive processes. Vitamin A in the form of beta-carotene is an antioxidant and free radical fighter. Vitamin E: Helps to relieve pain in CFS patients. Can also improve night leg cramps, which interferes with sleep. Vitamin C: Enhances immune function by increasing natural killer cells, B and T cells. Can prevent chronic bladder infections by acidifying urine. Vitamin D: Regulates immune functions of monocytes and neutrophils. Neutraphils are white blood cells that ingest invasive bacteria, and act as the first line of defense once bacteria makes it past the skin barrier. Magnesium: Involved with immune support. Working with malic acid, enhances immune function by increasing natural killer cells. Magnesium is also critical for the relief of muscle pain. Inositol: Enhances immune function by increasing natural killer cells. Malic Acid: Working with magnesium, improves energy levels by improving cellular functions. Especially important in muscle metabolism. Betaine: Works with B vitamins to synthesize amino acids, and acts as a precursor to SAM-e. SAM-e (S-adenosylmethionine) is a naturally-occurring molecule in the body, and may have an effect on overall mood elevation. Amino Acids: Glycine, Serine, Taurine, Tyrosine are essential for the production of energy in the body. Also essential for brain function. Zinc: Supports the immune system by enhancing neutrophils activity and supporting healthy antigen-antibody binding. Selenium: Supports immune function by enhancing antibody production. Fructooligosaccharides: Provides nutrition for good bacteria in the intestinal tract, improving digestion and healthy microflora. All of the vitamins, minerals, and other nutritional supplements on the list are important to ensure recovery from chronic fatigue syndrome. To ensure that your nutritional supplement regimen contains all of these ingredients, look for a powdered supplement formulated specifically for CFS/FMS sufferers that can be reconstituted in a beverage of your choice. A powdered drink mix is a pleasant, easy way to ensure that you are taking all of the needed vitamins, minerals, and amino acids that will give you the needed energy to recover from your illness. B Vitamin Complex for Energy In addition to the powdered energy drink mix, it is important that you also take a vitamin B-complex supplement specifically formulated for people with CFS/FMS. The B vitamin formula, which should include niacinamide, thiamin, riboflavin, vitamin B6, folic acid, vitamin B12, pantothenic acid, and choline, is especially important to restore the energy production needs of your body, as well as for mental function. It is also important to make sure that the dosages are high enough CFS/FMS needs. The chart in the next column lists the B vitamins that are critical for people suffering from CFS/FMS. B Vitamins Effect on Chronic Fatigue Syndrome Studies have demonstrated that people with CFS/FMS are often deficient in many of the B vitamins, which tends to worsen their symptoms of fatigue and mental “fogginess” and ultimately lead to a weakened immune system. B vitamins - Effect on Energy Thiamine (B1) - Essential in the process of energy production. This vitamin also removes lactic acid from muscles, which causes them to be sore in fibromyalgia patients. Riboflavin (B2) - Riboflavin (vitamin B2) is crucial in the production of body energy. Supports healthy gluthathione reductase activity, which helps maintain gluthathione, a major protector against free radical damage. Vitamin B2 itself also has antioxidant qualities. Niacinamide(B3) - Essential vitamin that is a component of the body’s energy furnace, helping to improve fatigue and “brain fog”. Pantothenic Acid (B5) - This vitamin improves adrenal gland function, which will boost energy levels. It can also aid in weight loss by decreasing appetite. Vitamin B6 - Working along with thiamine, this vitamin is critical in the process of energy production. Vitamin B12 - Important for brain function and nerve repair. Aids in relieving fatigue symptoms in CFS patients. Folic Acid - Aids in strengthening the immune system, and aids in mental clarity and concentration. Q. What other supplements can help me with CFS? A. Many people with CFS/FMS are suffering from adrenal burnout. Adrenal burnout occurs when the adrenal glands are constantly producing cortisol in response to chronic stress like that seen in cases of CFS. Over time, this exhausts the adrenal reserve, meaning the adrenal gland can no longer increase cortisol production in response to stress. The good news is that changes in our hormone levels can return to normal when stress is decreased. However, in cases of CFS that return to normal can be made much simpler by using a glandular therapy regimen to ensure healthy cortisol levels and adrenal function. Glandular therapy uses the concentrated forms of bovine (cow) or porcine (pig) glands to improve the health of our glands. Pioneers in the field of endocrinology (the study of hormones) hypothesized that glandular extracts work by providing nutrients the body lacks and thus repairing the malfunctioning gland. Adrenal Extract If CFS has left your adrenal glands in a stressed-out state, you should see great results by taking adrenal supplements. Be sure to buy an adrenal extract supplement that contains both whole adrenal and adrenal cortex extracts. The best adrenal supplement should also contain vitamin C, vitamin B6, L-tyrosine, betaine, pantothenic acid and licorice. Licorice contains glycyrrhizin, which is broken down into glycyrrhizic or glycyrrhetinic acid. This compound inhibits the activity of an enzyme that turns active cortisol into inactive cortisol. While in high amounts (greater than 100 mg of glycyrrhizic acid/day), licorice administration causes hypertension, no such effects have been observed at lower doses. Experts have speculated that inhibition of the cortisol-converting enzyme may reduce cortisol-related symptoms associated with adrenal insufficiency. The adrenal glands use these nutrients to manufacture cortisone and other compounds. It just makes sense to purchase an adrenal supplement with these supportive ingredients. The Road to Recovery-Adequate Sleep Disordered sleep is the underlying process that drives many of the symptoms of CFS/FMS. The most effective way to eliminate pain in CFS/FMS is to get seven to nine hours of deep sleep each night. However, getting adequate sleep is easier said than done for CFS sufferers with underlying fibromyalgia symptoms. The muscle knots of fibromyalgia make it uncomfortable to lie in one position for an extended time, causing difficulty in returning to deep sleep. Because of this, people with CFS/FMS do not stay in deep stages of sleep to recharge their “batteries.” In addition, poor sleep can cause and be caused by the suppression of the hypothalamus gland, which causes the brain to think it is daytime instead of night time. It may be helpful to use herbal products to promote good quality sleep. There are many natural supplements that are marketed as sleep formulas. To get the best results, it is very important that the right ingredients are in the sleep formula you buy. Therefore, it is important to look for an herbal sleep formula that is especially formulated for people with CFS/FMS. The combination of herbs is important as each herb addresses a different aspect of sleeplessness and muscle tension. Ingredients - Effect on Sleep Wild Lettuce - Has been found to have sedative effects. Hops - Acts as mild sedative and has a sleep-inducing effect. Jamaica Dogwood Has been found to be mildly sedative and is often used for anxiousness. L-Theanine - Causes significant increases of neurotransimitter concentrations in the brain, which promotes muscle relaxion and improves sleep. Valerian - This herb has been clinically studied for its ability to improve sleep quality. Passionflower - This herb eases nervousness and insomnia. Putting It All Together After a good night’s rest, a powdered energy drink mix formulated for people with CFS/FMS should be drunk along with a well-balanced breakfast as discussed earlier. In addition to the nutritional beverage mix, a vitamin B complex supplement designed specifically for CFS sufferers, also discussed earlier, containing niacinamide, thiamin, riboflavin, vitamin B6, vitamin B12, pantothenic acid, and choline, should be taken every morning. The nutritional drink mix and the vitamin B complex supplement will ensure that your body has all the vitamins, minerals, amino acids, and other nutrients, to combat your overwhelming fatigue, pain, and “brain fog.” Taking a daily adrenal supplement, like the one discussed earlier, will provide the much-needed (and often depleted) nutrients your body may be lacking, and help you recover lost energy. Together, these four interventions: sleep formula; morning energy drink; energy B complex supplement; and an adrenal complex- can make an incredible difference that you should begin to notice within 2-3 weeks of starting this program. Conclusion Chronic fatigue syndrome and fibromyalgia are complex physical diseases with physical causes. The unrelenting symptoms of fatigue, pain, and mental fogginess can be overwhelming and frightening. Partnering with a healthcare practitioner specializing in CFS and utilizing different medical treatments, supportive therapies, and lifestyle changes are healthy ways to combat chronic fatigue syndrome. And taking nutritional supplements formulated specifically for people with CMS/FMS that help boost energy or help you get a good night’s sleep can give you critical control over the outcome of your illness and set you on the road to recovery.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1475) Slimaluma Plus – Appetite Control
Date:
August 29, 2006 01:22 PM
Slimaluma Plus – Appetite Control with Green Tea and Yerba Mate
Now Vitamins Slimaluma plus contains a proprietary standardized extract of Caralluma fimbriata—a succulent, edible cactus that grows native throughout
Here’s how it works. As the stomach fills, it sends a signal to the brain’s hypothalamus region, letting it know that it is time to stop eating. Slimaluma is rich in naturally occurring compounds known as pregnane glycosides that interfere with the timing of this signal. This, in the eyes of researchers, is what causes users to experience feelings of fullness, even if they have not eaten. Slimaluma has also been shown to inhibit the formation of two enzymes involved in fat synthesis, allowing the body to convert more fat into energy, while sparing vital muscle proteins.
Now Vitamins Slimaluma Plus is a non-thermogenic, stimulant-free dietary supplement that is idea for individuals working to achieve a healthy body weight by establishing better eating habits.
Slimaluma is a trademark of Bencor Pacific, Inc.
* these statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
-- Buy Slimaluma Plus from Now Vitamins at Vitanet
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1360) What other supplements can help me with CFS?
Date:
December 10, 2005 03:21 PM
A. Many people with CFS/FMS are suffering from adrenal burnout. Adrenal burnout occurs when the adrenal glands are constantly producing cortisol in response to chronic stress like that seen in cases of CFS. Over time, this exhausts the adrenal reserve, meaning the adrenal gland can no longer increase cortisol production in response to stress. The good news is that changes in our hormone levels can return to normal when stress is decreased. However, in cases of CFS, that return to normal can be made much simpler by using a glandular therapy regimen to ensure healthy cortisol levels and adrenal function. Glandular therapy uses the concentrated forms of bovine (cow) or porcine (pig) glands to improve the health of our glands. Pioneers in the field of endocrinology (the study of hormones) hypothesized that glandular extracts work by providing nutrients the body lacks and thus repairing the malfunctioning gland. Adrenal Extract If CFS has left your adrenal glands in a stressed-out state, you should see great results by taking adrenal supplements. Be sure to buy an adrenal extract supplement that contains both whole adrenal and adrenal cortex extracts. The best adrenal supplement should also contain vitamin C, vitamin B^, L-tyrosine, betaine, pantothenic acid and licorice. Licorice contains glycyrrhizin, which is broken down into glycycrrhizic or glycycrrhetinic acid. This compound inhibits the activity of an enzyme that turns active cortisol into inactive cortisol. While in high amounts (greater than 100 mg of glycycrrhizic acid/day), licorice administration causes hypertension, no such effects have been observed at lower doses. Experts have speculated that inhibition of the cotisol-converting enzyme may reduce cortisol-related symptoms associated with adrenal insufficiency. The adrenal glands use these nutrients to manufacture cortisone and other compounds. It just makes sense to purchase an adrenal supplement with these supportive ingredients. The Road to Recovery- Adequate Sleep Disordered sleep is the underlying process that drives many of the symptoms of CFS/FMS. The most effective way to eliminate pain in CFS/FMS is to get seven to nine hours of deep sleep each night. However, getting adequate sleep is easier said then done for CFS sufferers with underlying fibromyalgia symptoms. The muscle knots of fibromyalgia make it uncomfortable to lie in one position for an extended time, causing difficulty in returning to deep sleep. Because of this, people with CFS/FMS do not stay in deep stages of sleep to recharge their “batteries.” In addition, poor sleep can cause and be caused by the suppression of the hypothalamus gland, which causes the brain to think it is daytime instead of night time. It may be helpful to use herbal products to promote good quality sleep. There are may natural supplements that are marketed as sleep formulas. To get the best results, it is very important that the right ingredients are in the sleep formula you buy. Therefore, it is important to look for an herbal sleep formula that is especially formulated for people with CFS/FMS. The combination of herbs is important as each herb addresses a different aspect of sleeplessness and muscle tension. Putting It All Together After a good night’s rest, a powdered energy drink mix formulated for people with CFS/FMS should be drunk along with a well-balanced breakfast as discussed earlier. In addition to the nutritional beverage mix, a vitamin B complex supplement designed specifically for CFS sufferers, also discussed earlier, containing niacinamide, thiamin, riboflavin, vitamin B6, vitamin B12, pantothenic acid, and choline, should be taken every morning. The nutritional drink mix and the vitamin B complex supplement will ensure that your body has all the vitamins, minerals, amino acids, and other nutrients, to combat your overwhelming fatigue, pain, and “brain fog.” Taking a daily adrenal supplement, like the one discussed earlier, will provide the much needed (and often depleted) nutrients your body may be lacking, and help you recover lost energy.
Together, these four interventions: sleep formula; morning energy drink; energy B complex supplement; and an adrenal complex can make an incredible difference that you should begin to notice within 2-3 weeks of starting this program.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1010) What are the complications of chronic fatigue syndrome?
Date:
December 10, 2005 03:14 PM
A. The patterns of CFS vary from individual to individual. However, many common patterns of symptoms are seen in CFS suffers. These symptoms and problems interact and create new symptoms and problems. For example, infections and disrupted sleep can lead to digestive, hormone, and immune problems. Infections The most notorious pattern seen in CFS is the one in which a person suddenly comes down with a flu-like illness that doesn’t go away. These viral or bacterial infections can suppress the body’s master gland, the hypothalamus. Since the hypothalamus controls the other glands, including the adrenals, ovaries, testes, and thyroid, suppression of this gland will lead to a subtle but debilitating decrease in the functioning of all glands and their hormones. Suppressed hypothalamic function from chronic infections can then trigger sleep dysfunction. Disrupted Sleep The suppression of the hypothalamus gland can lead to poor sleep because the body confuses its day/night cycles. Because of this, people with CFS have trouble staying in the deep, restorative stages of sleep that “recharge their batteries.” Poor sleep can cause immune suppression, which may lead to secondary bowel infections. The bowel infections seen in people with CFS can cause decreased absorption of nutrients, which can lead to chronic vitamin and mineral deficiencies.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1008) Hoodia Extract - Discover the Contemporary Use for a Traditional Food Source
Date:
June 29, 2005 09:59 AM
Hoodia Extract - Discover the Contemporary Use for a Traditional Food Source The San Tribesmen of the Kalahari Desert in southern Africa have known for millennia what we’ve only recently discovered; that the cactus-like Hoodia gordonii plant can be used as a healthy alternative food source. Because Source Naturals is dedicated to your good health, we’ve fused ancient San tradition with modern science to develop HOODIA EXTRACT. The sustenance the San derived from the hoodia plant as a main food source allowed them to travel lightly without the burden of extra food to hinder their journey on long hunting trips. With the introduction of our high quality HOODIA EXTRACT, Source Naturals offers you a safe, natural solution to achieving and maintaining a healthy lifestyle, and the chance to discover the contemporary use for the powerful nutritional supplement everyone’s looking for. HOODIA EXTRACT underlines Source Naturals commitment to bringing you the highest quality dietary supplements in your steps toward good health. An Age Old Tradition Life in southern Africa’s Kalahari Desert could be cruel. But even without modern research, the San Tribesmen knew their nutritional needs could be met with a remarkable botanical. For more than a hundred thousand years the San thrived as hunter-gatherers; their success dependant on their ability to locate food. Their treks across the Kalahari would last for months, even years, with the men hunting for antelope, and the women foraging for what became the main staple in their diet: fruit, nuts, and plants. None of their traditional food sources were more important than the phenomenal Hoodia gordonii plant. The hoodia plant became their chief source of sustenance while roaming the desert. Fruit and meat spoiled, nuts never lasted, but the stems and roots of that plant were special. A Special Plant Despite its similar appearance, the cactus- like hoodia is characterized as a succulent plant, which is a member of the milkweed family. Though there are about 20 species within the family, the active ingredient of hoodia is found only in the gordonii variety. Experts in succulent horticulture have helped ensure that the material Source Naturals uses to make HOODIA EXTRACT is gathered from authentic Hoodia gordonii sources. A Potent Extract The secret of HOODIA EXTRACT lies in the plant’s active ingredient; a substance containing previously unknown molecules discovered by South African scientists, and found to interact with the hypothalamus. Through painstaking chemical testing to assure quality and potency, Source Naturals has gone to great lengths to develop an extract that is best for the supplemental needs of its consumers. Every bit of the certified material Source Naturals receives is put through high tech chromatographic analysis to verify the purity of the active constituents needed to make HOODIA EXTRACT. A Responsible Company HOODIA EXTRACT has been produced with environmental sustainability in mind. Using only materials safely cultivated from the stems of seedlings grown on approved farms in South Africa, Source Naturals has made certain those materials were gathered with the knowledge and help of the San people to better preserve the Kalahari’s natural resources. A Wellness Revolution in Nutritional Health With today’s people faced with a multitude of nutritional problems, it is increasingly critical for us to take charge of our own well-being. Source Naturals is devoted to providing the highest quality products designed to supplement your diet and aid in your pursuit of a healthy lifestyle. HOODIA EXTRACT is available at your local health food store in 250mg capsules or tablets. Source Naturals - providing nutritional benefits offered only in the natural products marketplace.
References
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=518) Stomach Ulcers
Date:
June 23, 2005 11:24 AM
Stomach Ulcers Ironically, if you suffer from a peptic or duodenal ulcer, the last thing you feel probably feel inclined to take is hot Cayenne Pepper. While it goes against eve rything we’ve ever heard about what aggravates an ulcer, the facts are that most “spicy” foods do just the opposite. Capsicum has the ability to serve as a local anesthetic to ulcerated tissue and can even help to control bleeding. While some individuals may be bothered by eating “peppery” or spicy foods, these foods do not cause the formation of gastric ulcers in normal people. What is particularly interesting is that people suffering from ulcers who would normally avoid Cayenne Pepper, may actually benefit from its therapeutic action. In addition, taking Capsicum may significantly reduce the risk of ever developing a peptic ulcer. A Chinese study published in 1995 stated, “Our data supports the hypothesis that the chile used has a protective effect against peptic ulcer disease.”52 Another 1995 study found that Capsicum can even protect the stomach lining from aspirin induced ulcers.5 3 As most of us are aware, aspirin can cause stomach ulceration in certain individuals if a sensitivity exists or if taken with too little liquid. Researchers concluded after experiments with human volunteers that the capsaicin content of capsicum has a pronounced gastro - protective effect on the mucous membranes of the stomach.5 4 Eighteen healthy volunteers with normal gastrointestinal mucosa took chile and water followed by 600 mg of aspirin and water. The study was conducted over a period of four weeks. Endoscopy results showed that taking 20 gm of chile before the aspirin definitely demonstrated a protective action on the stomach lining.55 In short, Capsicum has the ability to rebuild stomach tissue. Note: The ability of Capsicum to bring blood to regions of tissue at a faster rate boosts the assimilation of foods that are consumed with it.56 Several clinical studies support this phenomenon. It is thought that Capsicum initiates the release of certain substances which increase secretions and facilitate better profusion of blood to the stomach and intestines.57 Capsicum can increases the flow of digestive secretions from the salivary, gastric and intestinal glands. Capsicum and the Gastro-Intestinal Tract In 1992, researchers tested the effect of chile or Capsicum on gastrointestinal emptying. Eight healthy volunteers were evaluated before and after the addition of Capsicum to their meals. The results conclusively demonstrated that the ingestion of Capsicum greatly effects intestinal transit time.58 If food moves faster through from the stomach through the intestines, caloric assimilation and bowel evacuation may be influenced for the better. Capsicum seems to “speed up” various physiological processes. To add transit time to the list of functions Capsicum boosts comes as somewhat of a surprise and additional benefit. Capsicum and Weight Loss Capsicum may be an unheralded weight loss aid that is perfectly safe to use. Studies have suggested that Capsicum can slow fat absorption in the small intestines and actually boost the metabolic rate so the thermogenesis (fat burning) is enhanced.5 9 In many instances excessive weight gain is thought to be a result of a sluggish metabolism. Capsicum has been singled out by herbalists as an herb which may boost the burning of fat.60 Unlike other stimulants, Capsicum does not cause palpitations, hyperactivity or a rise in blood pressure. For this reason, it may be a valuable weight loss supplement that has been generally overlooked. Psoriasis As mentioned earlier, capsaicin has the ability to inhibit a neurotransmitter called substance P. Interestingly, an excess of substance P has been associated with psoriasis. Michael T. Murray, in his book, The Healing Power of Herbs, points out that this finding led researchers to study the effects of capsaicin ointments on psoriasis .61 Regarding the use of such an ointment for psoriasis, he states: “ . . . In one double-blind study, forty-four patients with symmetrically distributed psoriasis lesions applied topical capsaicin to one side of their body and a placebo to the other side. After 3 to 6 weeks, significantly greater reductions in scaling and redness were observed on the capsaicint reated side. Burning, stinging, itching, and skin redness were noted by nearly half of the patients initially, but these diminished or vanished on continued applications.”62 There is no question that capsaicin based ointments should be employed for psoriasis. Tests have conclusively found that treating psoriasis with capsaicin caused significant improvement in a variety of symptoms as well as the severity of the attack.63 Rhinitis Capsicum has also scientifically proven its value in people suffering from vasomotor rhinitis. By using Capsicum in spray form, researchers found that it was able to significantly reduce nasal obstruction and secretion.64 It is important to understand that in these particular instances, a Capsicum solution was applied directly to the mucous membranes of the nose. It did initially cause a painful burning and stimulated nasal secretion. However, in time, after repeated applications, these side effects disappeare d .6 5 Apparently, Capsicum may block the action of peripheral nerve endings which may stimulate nasal secretion and blockage. More study of Capsicum as a viable treatment for rhinitis has been recommended. Note: One of the many pro p e rties of Capsicum is its ability to b reak up mucous congestion which makes expectoration much easier.66 For this reason, Capsicum is recommended for upper respiratory infections which are characterized by excess mucus. Fever and Chills While it may seem somewhat contradictory, Capsicum actually l owers the temperature of the body by stimulating the region of the hypothalamus, which cools the body.6 7 “The ingestion of cayenne peppers by cultures native to the tropics appears to help these people deal with high temperature s . ”68 Capsicum also pro- motes perspiration which helps to cool the body off. In tropical areas, local people eat substantial amounts of hot peppers on a daily basis which helps to boost the elimination of sweat and thereby keeps body temperature down. This same mechanism can be used to treat fever and chills. In addition to this action, using Capsicum for any infection that may be causing a fever is also warranted. Capsicum helps to boost immune defenses and fights microorganism invasion.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=406) Anti-Aging Nutrients
Date:
June 18, 2005 09:07 AM
Anti-Aging Nutrients by Edward C. Wallace, DC, ND Energy Times, February 3, 2000 What's the big deal about trying to live longer? As you grow older (and the American population grows older alongside you) you may want to postpone the inevitable. Few wish to hasten "the journey from which no traveler returns." But as we approach that final bon voyage, chances are we desire clear sailing-aging without disability and with a peaceful, easy feeling. How Do We Age? Science has long puzzled about what causes the wrinkles, pains and deterioration of aging. In the search for causes, two basic theories have won over the most proponents: The first holds that cells are programmed with biological clocks that predetermine how many times they can reproduce before becoming non-functional. This theory has been largely formulated by the researcher Leonard Hayflick, MD. The second basic theory, introduced by Denham Harman, MD, PhD, in the mid 1950s, holds that cells eventually break down due to attack by caustic molecules called free radicals that cause oxidative stress. Programmed Cell Theory In the early '60s, Dr. Hayflick observed that human fibroblasts (cells from connective tissue) in the laboratory refused to divide more than about 50 times. Dr. Hayflick also found that even if he froze the fibroblasts after 20 divisions, they would remember that they only had 30 divisions left after thawing. Fifty cell divisions have been called the "Hayflick limit." Based on this research, scientists theorize that cells maintain a genetic clock that winds down as old age ensues. Many researchers believe the hypothalamus gland is the force behind our aging clocks, signaling the pituitary gland to release hormones that cause aging. Free Radical/Oxidative Stress Theory The other popular theory of aging pictures the human body as a cellular battlefield where attackers called free radicals damage our cells and tissues, making them age. In this scenario, a process called oxidation is the chief aging villain. On a microscopic level, oxidation generally entails molecules or atoms losing electrons. (Gaining electrons is called reduction.) The molecules or atoms that take these electrons are oxidizing agents. Free radicals are substances that can exist with missing electrons, making them readily able to donate or accept electrons and damage structures in cells. As such, they are highly reactive, binding with and destroying important cellular compounds. Most of the free radicals in your body are made during metabolic processes. More are added from the food you eat and environmental pollution. Most of these free radicals contain oxygen molecules. As each cell makes energy in little structures called mitochondria, free radicals result. These oxidant by-products can damage DNA, proteins and lipids (fats). Consequently, toxic by-products of lipid peroxidation may cause cancer, inhibit enzyme activity and produce mutations in genetic material that make you age faster. DNA Repair Theory Free radical damage to DNA can cause cells to mutate or die. Your body makes enzymes that can repair this damage and slow aging. But, over time, the amount of damage overwhelms the body's ability to fix things. As cells grow older, their ability to patch up DNA diminishes and the rate of damage proceeds faster than repair. The result: We age and eventually die. What Can We Do? The free radical theory of aging suggests that taking antioxidants (compounds known to prevent free radical damage) in our food or as supplements may slow aging. In the publication Age (18 [51] 1995: 62), it was reported that "aging appears to be caused by free radicals initiated by the mitochondria at an increasing rate with age. Superoxide and hydrogen peroxide radicals formed by the mitochondria during normal metabolism are major risk factors for disease and death after about the age of 28 in developed countries. Antioxidants from the diet lower the production of free radicals without impairing essential reactions to maintain body function." Antioxidant Protection Common dietary antioxidants include: vitamins E and C, carotenes, sulphur containing amino acids, co-enzyme Q10 and flavonoids (a group of plant compounds or pigments responsible for the color in fruits and flowers). In addition, melatonin, DHEA and the amino acid compound glutathione may also prove of benefit. Glutathione along with the enzyme glutathione peroxidase are an essential part of free radical "quenching." (Quenching means changing free radicals into benign substances no longer capable of harm.) Deficiencies may suggest a decreased capacity to maintain detoxification and metabolic reactions in which glutathione plays a role, resulting in increased free radical stress and/or lipid peroxidation. Drinking too many alcoholic beverages can result in glutathione deficiency. In a study in which 39 healthy men and 130 healthy women between the ages of 20 and 94 were evaluated for glutathione levels, the older subjects had significantly decreased levels (especially in the 60 to 79-year-old group). The authors felt that physical health and longevity were closely related to glutathione levels (Jrnl Lab & Clin Sci 120(5), Nov. 1992: 720-725). Poor nutrition and/or deficiencies in essential micronutrients and many prescription medications may contribute significantly to detoxification capacity in an aged individual. All of these circumstances are common in the elderly. Eating a poor diet that contains too many processed foods without many fruits and vegetables can compromise your body's ability to detoxify pollutants, toxins and other harmful compounds. That can set off metabolic processes capable of fomenting large increases in free radical stress that can accelerate aging. Unfortunately, even in a country as prosperous as our own, nutrient deficiencies are frequent, especially in older citizens. Nutrition Deficiencies A study that looked at what elderly people consumed compared their reported intake with the 1989 Recommended Dietary Amount (RDA) and 1980 RDA: One of four people consumed only two-thirds of the RDA for calories and 60% consumed less than two-thirds of the RDA for vitamin D. As for other nutrients, 50% were found to have inadequate zinc levels (less than two-thirds of the RDA), 31% lacked calcium, 27% were short of vitamin B6, 25% didn't get enough magnesium, 7% missed out on folate and 6% ate less than two-thirds of the requirement for vitamin C (Nutrition Reviews (II), September 1995: S9-S15). When researchers examine what everyone in the U.S. eats, they find that only 9% of Americans consume the recommended five servings of fruits and/or vegetables per day (Proceedings of the National Academy of Sciences, Sept 1993). A diet high in fruits and vegetables is naturally high in antioxidant compounds and is believed to help you live longer. Unfortunately, if you buy your produce in the supermarket, those fruits and vegetables may also be rich in pesticide and herbicide residues (Consumer Reports, March 1999). Obviously, organic produce lacks these residues. But, in any case, research continues to indicate that a diet low in meats and animal fat and high in vegetables protects against antioxidant damage. Longevity Diets A six-year study of 182 people over age 70 in rural Greek villages found that those following their traditional diet of olive oil, whole grain breads, fresh fruits and vegetables and wine were less likely to die during the study than those who consumed more red meat and saturated fat. The most important foods in lowering the risk of early death included fruits, vegetables, legumes (peas and beans), nuts, dairy products and cereals (BMJ 311, 1995: 1457-1460). Another article in Epidemiology highlights the evidence that eating a vegetarian diet increases your chances of living longer. Included in this survey is a recent country-wide study of diet and health in China, showing that the traditional near vegetarian diet of 10% to 15% of calories coming from dietary fat reduced the chances of heart disease, diabetes and many types of cancers (Epidemiology 3[5], 1992: 389-391). Staying Alive Staying skinny and limiting what you eat may also increase longevity. Scientific studies have previously shown that being overweight can theoretically curtail your life, increasing the risk of heart disease, diabetes and other life-shortening conditions. Animal studies have also shown that restricting food can slow diseases associated with aging. Researchers believe that cutting calories helps your immune system stay younger by reducing the formation of substances that are called proinflammatory cytokines. Specifically reducing your intake of fatty foods may decrease your chance of coming down with autoimmune diseases. Researchers think omega-6 fatty acid vegetable oils (like corn oil) may increase free radical formation and decrease levels of antioxidant enzyme messenger RNA in addition to other effects (Nutrition Reviews 53[4], 1995: S72-S79). Another study found that cutting calories lowers the levels of oxidative stress and damage, retards age-associated changes and extends maximum life span in mammals (Science 273, July 5, 1996: 59-63). In yet another study, it was shown that caloric restriction early in the life of lab animals increased their life span by a whopping 40% (Australian Family Physician 23[7], July 1994: 1297-1305). Today's modern higher-fat, low-fiber diet with substantial sugar consumption represents everything the longevity researchers say you shouldn't eat. Longevity and Exercise Exercise may slow aging. When researchers looked at the exercise habits of 17,000 men, average age of 46, they found that those who took part in vigorous activity lived longer. Exercise can improve both cardiac and metabolic functions within the body, while also decreasing heart disease risk. Even modest exercise has been shown to improve cholesterol and blood sugar levels (JAMA 273[15], April 19, 1995: 1179-1184). In a study of how exercise affects your chances of living longer, 9,773 men underwent preventive medicine examinations on two different occasions. When the researchers looked at who lived longest, they found the highest death rate was in men who were unfit during both physical exams. The Treadmill of Life The lowest death rate was in the men who worked out and were in good shape. The researchers concluded that for each minute increase in how long a man could keep treading on a treadmill (between the first and second exam) there was a corresponding 7.9% decrease in the risk of dying (JAMA 273 [14], April 12, 1995: 1093-1098). Since exercise can increase oxygen consumption up to 10 times, boosting the rate of production of free radicals, researchers believe that older individuals need more antioxidant nutrients to protect them. In a paper published in Aging Clinical and Experimental Research (1997), researchers stated that if you regularly exercise in your golden years, you should take more antioxidant vitamins to compensate for this risk. Longevity Supplementation Melatonin is not often thought of as an antioxidant, but, instead, as a sleep aid. Melatonin, however, is an effective and efficient free radical scavenger and may help stave off the effects of aging. Melatonin protects against what are called hydroxyl free radicals. Research shows that older people's lack of melatonin may make them more susceptible to oxidative stress. In one study, researchers felt that new therapies aimed at stimulating melatonin synthesis may eventually lead to therapies for the prevention of diseases related to premature aging (Aging and Clinical Experimental Research 7[5], 1995: 338-339). Melatonin was shown to provide antioxidant protection in several ways. Toning Down Enzymes Melatonin can ease the effects of enzymes that generate free radicals, enhance the production of glutathione peroxidase (an antioxidant) and defuse the caustic action of free radicals that contain hydroxyls. In several studies, DHEA supplementation has been shown to potentially revive immune function in older adults (Exp. Opin. Invest. Drugs 4[2], 1995: 147-154). In a study of 138 persons older than 85 years compared to 64 persons 20 to 40 years of age, scientists found that the younger people had four times as much DHEA in their bodies. The researchers believe that our bodies make less and less DHEA as we get older. The authors of this study raise the possibility that declining DHEA may be partly to blame for our biological clocks running down (New York Academy of Sciences 1994: 543-552). Vitamins E & C A growing body of research also supports the benefits of taking vitamins E and C to hold off the effects of getting old. Researchers writing in Free Radicals and Aging (1992: 411-418) point out that as you get older your body is home to more and more free radical reactions that may lead to degenerative diseases like heart disease and arthritis. Research has found that in older people with exercise-induced oxidative stress, taking vitamin E every day may significantly fight off free radicals. (To investigate this effect, scientists measured waste products in urine that result from free radical reactions.) Their conclusion: Dietary antioxidants such as vitamin E may be beneficial. Chronological Age Vs.Biological Age Vitamin C also looks to scientists like a good anti-aging bet. Research in the Journal of Advancement in Medicine, (7[1], Spring 1994: 31-41) showed that folks consuming larger amounts of vitamin C were less likely to experience clinical problems at all ages. Those taking in less than 100 mg of vitamin C per day also suffered the most problems. In this research, individuals over 50 years of age who daily consumed the largest amount of vitamin C were as healthy or healthier than the 40 year olds who were taking the least amount of vitamin C. Similar Relationship A similar relationship appears to exist for vitamin E and serum cholesterol levels. In a study of 360 physicians and their spouses, researchers found that people in their 50s who consumed more vitamin E had lower cholesterol than those in their 30s who were taking less. And the longevity beat goes on: In a study evaluating environmental tobacco smoke and oxidative stress, researchers divided 103 people into three groups. Researchers blew smoke at 37 of these folks without protection while 30 of them got to breathe tobacco smoke but took antioxidant supplementation. Another 36 of them merely had to read magazines from doctors' offices. The results: After 60 days of supplementation the antioxidant folks had a 62% reduction in evidence of oxidative damage to their DNA. Cholesterol levels dropped and so did antioxidant enzyme activities. The researchers concluded that taking antioxidants provided a modicum of protection against environmental poisons. The range of antioxidant nutrients used in this study included: beta-carotene, vitamin C, vitamin E, zinc and selenium as well as copper (Cancer Epidemiol Biomarkers Prev 7, November 1998: 981-988). Carotenoids When you mention carotene or carotenoids, most people think of the beta carotene that makes carrots orange. But more than 600 carotenoids are present in colorful vegetables and many of these misunderstood substances are more potent antioxidants than beta-carotene. Carotenoids have been shown to destroy oxygen free radicals in lipids (fats), help protect our cells from the sun's ultra violet radiation and enhance our natural immune response (J. Nutr 119[1], Jan. 1989: 112-115). Some evidence seems to show that how much carotenoids you (and other mammals) have in your cells may be the predominant factor in determining life span (Proc Natl Acad Sci 82 [4], 1985: 798-802). Therefore, a diet rich in carotenoids (leafy green vegetables, carrots, yams, sweet potatoes, squash, citrus fruits and tomatoes) along with supplementation seems to be just what the fountain of youth ordered. Flavonoids Flavonoids, a group of antioxidant plant pigments, seem to be able to protect specific organs. For instance, the flavonoids in milk thistle (Silybum marianum) have been used for ages for liver problems. Bilberry has been found protective for the eye and hawthorn for the heart and circulatory system. Numerous studies have shown the many beneficial effects of flavonoids with perhaps the best known being the ability of anthocyanidins in wine and grape seed extract to help protect your blood vessels and capillaries from oxidative damage (Phytotherapy 42, 1986: 11-14; Am J Clin Nutr 61, 1995: 549-54). Flavonoids are found in vegetables and such fruits as blackberries, blueberries, cherries and grapes. A diet rich in these foods helps ensure an adequate intake of these important nutrient compounds. Amino Acid Health Methionine and cysteine are sulphur containing amino acids (protein building blocks), both of which are essential in maintaining levels of glutathione, a substance that plays a major role in quelling free radicals. Studies have found that as we age, the level of these important amino acids in our bodies decreases. (NEJM 312 [1], 1985: 159-68). As it has been shown that adding cysteine to the diet of test animals can increase their life expectancy considerably, researchers believe these amino acids can help us live longer too. Attitude & Behavior Get more sleep! A recent study showed that men who habitually napped were less likely to have a heart attack. The men in this research who regularly napped for at least 30 minutes per day had about a 30% reduction in heart problems while those who napped for a full hour had a 50% reduction compared to non nappers. Naps of longer duration did not seem to increase the benefit. In the same research, investigators also found that spending time with a pet or merely contemplating nature could also improve cardiac health. Sensuality, optimism and altruism also appeared to have health benefits (Family Practice News, December 15, 1998: 14-15). In another study, this one in American Psychologist, researchers from the University of California found that people who are self-indulgent, pampered and achieve by running roughshod over the competition are less likely to outlive their healthy peers. Being egocentric, impulsive, undependable and tough-minded were predictors of poor physical health and a shorter life. So loosen up and be nice to your fellow humans! (U.C. Davis Magazine, Fall 1995: 14). Longevity at Last While no one has suggested that taking supplements, eating vegetables or exercising can, as of yet, extend the human life span past the generally recognized limit of about 120 years, researchers believe they can improve your odds of longer life. And by staying healthier, your old age will be more enjoyable, too.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=377) Menopause: Disease or Condition?
Date:
June 13, 2005 03:44 PM
Menopause: Disease or Condition? by Mary Ann Mayo & Joseph L. Mayo, MD Energy Times, September 4, 1999 It's front-page news. It's politically correct and socially acceptable. Talking about menopause is in. Suddenly it's cool to have hot flashes. Millions of women turning 50 in the next few years have catapulted the subject of menopause into high-definition prominence. It's about time. Rarely discussed openly by women (what did your mother ever advise you?), meno-pause until recently was dismissed as "a shutting down experience characterized by hot flashes and the end of periods." Disparaging and depressing words like shrivel, atrophy, mood swings and melancholia peppered the scant scientific menopausal literature. What a difference a few years and a very vocal, informed and assertive group of Baby Boomers make. Staggered by the burgeoning numbers of newly confrontational women who will not accept a scribbled prescription and a pat on the head as adequate treatment, health practitioners and researchers have been challenged to unravel, explain and deal with the challenges of menopause. Not An Overnight Sensation Menopause, researchers have discovered, is no simple, clear cut event in a woman's life. The "change of life" does not occur overnight. A woman's body may begin the transition toward menopause in her early 40s, even though her last period typically occurs around age 51. This evolutionary time before the final egg is released is called the perimenopause. Erratic monthly hormone levels produce unexpected and sometimes annoying sensations. Even as their bodies adjust to lower levels of estrogen, progesterone and testosterone, some women don't experience typical signs of menopause until after the final period. A fortunate one-third have few or no discomforts. Hormonal Events According to What Your Doctor May Not Tell You About Premenopause (Warner Books) by John R. Lee, MD, Jesse Hanley, MD, and Virginia Hopkins, "The steroid hormones are intimately related to each other, each one being made from another or turned back into another depending on the needs of the body...But the hormones themselves are just part of the picture. It takes very specific combinations of vitamins, minerals and enzymes to cause the transformation of one hormone into another and then help the cell carry out the hormone's message. If you are deficient in one of the important hormone-transforming substances such as vitamin B6 or magnesium, for example, that too can throw your hormones out of balance. Thyroid and insulin problems, toxins, bad food and environmental factors, medication and liver function affect nutrient and hormone balance." The most important reproductive hormones include: Estrogen: the female hormone produced by the ovaries from puberty through menopause to regulate the menstrual cycle and prepare the uterus for pregnancy. Manufacture drops significantly during menopause. Estradiol is a chemically active and efficient form of estrogen that binds to many tissues including the uterus, breasts, ovaries, brain and heart through specific estrogen receptors that allow it to enter those cells, stimulating many chemical reactions. Estriol and estrone are additional forms of estrogen. Progesterone: also produced by the ovaries, it causes tissues to grow and thicken, particularly during pregnancy, when it protects and nurtures the fetus. Secretion ceases during menopause. Testosterone: Women produce about one-twentieth of what men do, but require it to support sex drive. About half of all women quit secreting testosterone during menopause. Estrogen's Wide Reach Since estrogen alone influences more than 400 actions on the body, chiefly stimulating cell growth, the effects of its fluctuations can be far-reaching and extremely varied: hot (and cold) flashes, erratic periods, dry skin (including the vaginal area), unpredictable moods, fuzzy thinking, forgetfulness, fatigue, low libido, insomnia and joint and muscle pain. Young women may experience premature menopause, which can occur gradually, as a matter of course, or abruptly with hysterectomy (even when the ovaries remain) or as a result of chemotherapy. Under such conditions symptoms can be severe. In the 1940s doctors reasoned that if most discomforts were caused by diminishing estrogen (its interactive role with progesterone and testosterone were underestimated), replacing it would provide relief. When unchecked estrogen use resulted in high rates of uterine cancer, physicians quickly began adding progesterone to their estrogen regimens and the problem appeared solved. For the average woman, however, hormone replacement therapy (HRT) became suspect and controversial, especially when a link appeared between extended use of HRT (from five to 10 years) and an increase in breast and endometrial cancers (Journal of Clinical Pharmacology 37, 1997). The result: Women have drawn a line in the sand between themselves and their doctors. Resolving The Impasse Since hormone replacement reduces the risk of major maladies like heart disease, osteoporosis, Alzheimer's, colon cancer and diabetes that would otherwise significantly rise as reproductive hormone levels decrease, most doctors recommend hormone replacement shortly before or as soon as periods stop. Hormone replacement also alleviates the discomforts of menopause. But only half of all women fill their HRT prescriptions and, of those who do, half quit within a year. Some are simply indifferent to their heightened medical risks. Some are indeed aware but remain unconvinced of the safety of HRT. Others complain of side effects such as bloating, headaches or drowsiness. Women's resistance to wholesale HRT has challenged researchers to provide more secure protection from the diseases to which they become vulnerable during menopause, as well as its discomforts. If the conventional medical practitioners do not hear exactly what modern women want, the complementary medicine community does. Turning to centuries-old botanicals, they have validated and compounded them with new technology. Their effectiveness depends on various factors including the synergistic interaction of several herbs, specific preparation, the correct plant part and dosage, harvesting and manufacturing techniques. Research demonstrates that plant hormones (phytoestrogens) protect against stronger potentially carcinogenic forms of estrogen while safely providing a hormone effect. Other herbs act more like tonics, zipping up the body's overall function. Help From Herbs Clinical trials and scientific processing techniques have resulted in plant-based supplements like soy and other botanicals that replicate the form and function of a woman's own estrogen. The complementary community also can take credit for pushing the conventional medical community to look beyond estrogen to progesterone in postmenopausal health. Natural soy or Mexican yam derived progesterone is formulated by pharmacologists in creams or gels that prevent estrogen-induced overgrowth of the uterine lining (a factor in uterine cancer), protect against heart disease and osteoporosis and reduce hot flashes (Fertility and Sterility 69, 1998: 96-101). A quarter of the women who take the popularly prescribed synthetic progesterone report increased tension, fatigue and anxiety; natural versions have fewer side effects. These "quasi-medicines," as Tori Hudson, a leading naturopathic doctor and professor at the National College of Naturopathic Medicine, Portland, Oregon, calls them, are considered "stronger than a botanical but weaker than a medicine." (Hudson is author of Gynecology and Naturopathic Medicine: A Treatment Manual.) According to Hudson, the amount of estrogen and progesterone in these supplements is much less than medical hormone replacement but equally efficacious in relieving menopausal problems and protecting the heart and bones. According to a study led by Harry K. Genant, PhD, of the University of California, San Francisco, "low-dose" plant estrogen derived from soy and yam, supplemented with calcium, prevents bone loss without such side effects as increased vaginal bleeding and endometrial hypoplasia, abnormal uterine cell growth that could be a precursor to endometrial cancer (Archives of Internal Medicine 157, 1997: 2609-2615). These herbal products, including natural progesterone and estrogen in the form of the weaker estriol or estrone, may block the effect of the stronger and potentially DNA-damaging estradiol. Soy in its myriad dietary and supplemental forms provides a rich source of isoflavones and phytosterols, both known to supply a mild estrogenic effect that can stimulate repair of the vaginal walls (Journal of the National Cancer Institute 83, 1991: 541-46). To enhance vaginal moisture, try the herb cimicifuga racemosa, the extract of black cohosh that, in capsule form, builds up vaginal mucosa (Therapeuticum 1, 1987: 23-31). Traditional Chinese herbal formulas containing roots of rehmannia and dong quai have long been reputed to promote vaginal moisture. Clinical research in Germany also confirms the usefulness of black cohosh in preventing hot flashes and sweating, as well as relieving nervousness, achiness and depressed moods caused by suppressed hormone levels. It works on the hypothalamus (the body's thermostat, appetite and blood pressure monitor), pituitary gland and estrogen receptors. Green tea is steeped with polyphenols, mainly flavonoids, that exert a massive antioxidant influence against allergens, viruses and carcinogens. The risks of estrogen-related cancers such as breast cancer are particularly lowered by these flavonoids, as these substances head directly to the breast's estrogen receptors. About three cups a day exert an impressive anti-inflammatory, antiallergenic, antiviral and anticarcinogenic effect. Other phytoestrogen-rich botanicals, according to Susun Weed's Menopausal Years: The Wise Woman Way (Ash Tree Publishing), include motherwort and lactobacillus acidophilus to combat vaginal dryness; hops and nettles for sleep disturbances; witch hazel and shepherd's purse for heavy bleeding; motherwort and chasteberry for mood swings; dandelion and red clover for hot flashes. Our Need For Supplements Adding micronutrients at midlife to correct and counter a lifetime of poor diet and other habits is a step toward preventing the further development of the degenerative diseases to which we become vulnerable. At the very minimum, you should take: a multivitamin/mineral supplement vitamin E calcium Your multivitamin/mineral should contain vitamins A, B complex, C, D, E, calcium, magnesium, potassium, copper and zinc. Look for a wide variety of antioxidants that safeguard you from free radical damage, believed to promote heart disease and cancer, as well as contribute to the aging process. Also on the list: mixed carotenoids such as lycopene, alpha carotene and vitamin C; and folic acid to help regulate cell division and support the health of gums, red blood cells, the gastrointestinal tract and the immune system. Studies indicate a deficiency of folic acid (folate) in 30% of coronary heart disease, blood vessel disease and strokes; lack of folate is thought to be a serious risk factor for heart disease (OB.GYN News, July 15, 1997, page 28). Extra vitamin E is believed to protect against breast cancer and bolster immune strength in people 65 and older (Journal of the American Medical Association 277, 1997: 1380-86). It helps relieve vaginal dryness, breast cysts and thyroid problems and, more recently, hit the headlines as an aid in reducing the effects of Alzheimer's and heart disease. It is suspected to reduce the thickening of the carotid arterial walls and may prevent the oxidation of LDL (bad) cholesterol, which contributes to the formation of plaque in arteries. Selenium also has been identified as an assistant in halting cancer (JAMA 276, 1996: 1957-63). The Omegas To The Rescue Essential fatty acids found in cold water fish, flaxseed, primrose and borage oils and many nuts and seeds are essential for the body's production of prostaglandin, biochemicals which regulate hormone synthesis, and numerous physiological responses including muscle contraction, vascular dilation and the shedding of the uterine lining. They influence hormonal balance, reduce dryness and relieve hot flashes. In addition, the lignans in whole flaxseed behave like estrogen and act aggressively against breast cancer, according to rat and human studies at the University of Toronto (Nutr Cancer 26, 1996: 159-65). Research has demonstrated that these omega-3 and omega-6 fatty acids can reverse the cancer-causing effects of radiation and other carcinogens (Journal of the National Cancer Institute 74, 1985: 1145-50). Deficiencies may cause swelling, increased blood clotting, breast pain, hot flashes, uterine and menstrual cramps and constipation. Fatigue, lack of endurance dry skin and hair and frequent colds may signal EFA shortage. Plus, fatty fish oils, along with vitamin D and lactose, help absorption of calcium, so vital for maintaining bone mass. In addition, studies show that the natural substance Coenzyme A may help menopausal women reduce cholesterol and increase fat utilization (Med Hyp 1995; 44, 403, 405). Some researchers belive Coenzyme A plays a major role in helping women deal with stress while strengthening immunity. Still Suffering? Can't shake those menopausal woes? Menopause imposters may be imposing on you: The risk of thyroid disease, unrelenting stress, PMS, adrenal burnout, poor gastrointestinal health and hypoglycemia all increase at midlife. Menopause is a handy hook on which to hang every misery, ache and pain but it may only mimic the distress of other ailments. For this reason every midlife woman should have a good medical exam with appropriate tests to determine her baseline state of health. Only with proper analysis can you and your health practitioner hit on an accurate diagnosis and satisfying course of therapy. And if menopause is truly the issue, you have plenty of company. No woman escapes it. No woman dies from it. It is not a disease but a reminder that one-third of life remains to be lived. Menopausal Baby Boomers can anticipate tapping into creative energy apart from procreation. If not new careers, new interests await. An altered internal balance empowers a menopausal woman to direct, perhaps for the first time, her experience of life. She has come of age-yet again. Gone is the confusion, uncertainty, or dictates of a hormone driven life: This time wisdom and experience direct her. There is no need to yearn for youth or cower at the conventional covenant of old age. Menopause is the clarion call to reframe, reevaluate and reclaim. Mary Ann Mayo and Joseph L. Mayo, MD, are authors of The Menopause Manager (Revell) and executive editors of Health Opportunities for Women (HOW). Telephone number 877-547-5499 for more information.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=330) Nutrients for Longevity
Date:
June 10, 2005 09:59 PM
Nutrients for Longevity by Edward C. Wallace, ND, DC Energy Times, September 1, 1999 What's the big deal about trying to live longer? As you grow older (and the American population grows older alongside you) you may want to postpone the inevitable. Few wish to hasten "the journey from which no traveler returns." But as we approach that final bon voyage, chances are we desire clear sailing-aging without disability and with a peaceful easy feeling. How Do We Age Science has long puzzled about what causes the wrinkles, pains and deterioration of aging. In the search for causes, two basic theories have won over the most proponents: The first holds that cells are programmed with biological clocks that predetermine how many times they can reproduce before becoming non-functional. This theory has been largely formulated by the researcher Leonard Hayflick, MD. The second basic theory, introduced by Denham Harman, MD, PhD, in the mid 1950s, holds that cells eventually break down due to attack by caustic molecules called free radicals that cause oxidative stress. Programmed Cell Theory In the early '60s, Dr. Hayflick observed that human fibroblasts (cells from connective tissue) in the laboratory refused to divide more than about 50 times. Dr. Hayflick also found that even if he froze the fibroblasts after 20 divisions, they would remember that they only had 30 divisions left after thawing. Fifty cell divisions have been called the "Hayflick limit." Based on this research, scientists theorize that cells maintain a genetic clock that winds down as old age ensues. Many researchers believe the hypothalamus gland is the force behind our aging clocks, signaling the pituitary gland to release hormones that cause aging. Free Radical/Oxidative Stress Theory The other popular theory of aging pictures the human body as a cellular battlefield where attackers called free radicals damage our cells and tissues, making them age. In this scenario, a process called oxidation is the chief aging villain. On a microscopic level, oxidation generally entails molecules or atoms losing electrons. (Gaining electrons is called reduction.) The molecules or atoms that take these electrons are oxidizing agents. Free radicals are substances that can exist with missing electrons, making them readily able to donate or accept electrons and damage structures in cells. As such, they are highly reactive, binding with and destroying important cellular compounds. Most of the free radicals in your body are made during metabolic processes. More are added from the food you eat and environmental pollution. Most of these free radicals contain oxygen molecules. As each cell makes energy in little structures called mitochondria, free radicals result. These oxidant by-products can damage DNA, proteins and lipids (fats). Consequently, toxic by-products of lipid peroxidation may cause cancer, inhibit enzyme activity and produce mutations in genetic material that make you age faster. DNA Repair Theory Free radical damage to DNA can cause cells to mutate or die. Your body makes enzymes that can repair this damage and slow aging. But, over time, the amount of damage overwhelms the body's ability to fix things. As cells grow older, their ability to patch up DNA diminishes and the rate of damage proceeds faster than repair. The result: We age and eventually die. What Can We Do The free radical theory of aging suggests that taking antioxidants (compounds known to prevent free radical damage) in our food or as supplements may slow aging. In the publication Age (18 [51] 1995: 62), it was reported that "aging appears to be caused by free radicals initiated by the mitochondria at an increasing rate with age. Superoxide and hydrogen peroxide radicals formed by the mitochondria during normal metabolism are major risk factors for disease and death after about the age of 28 in developed countries. Antioxidants from the diet lower the production of free radicals without impairing essential reactions to maintain body function." Antioxidant Protection Common dietary antioxidants include: vitamins E and C, carotenes, sulphur containing amino acids, co-enzyme Q10 and flavonoids (a group of plant compounds or pigments responsible for the color in fruits and flowers). In addition, melatonin, DHEA and the amino acid compound glutathione may also prove of benefit. Glutathione along with the enzyme glutathione peroxidase are an essential part of free radical "quenching." (Quenching means changing free radicals into benign substances no longer capable of harm.) Deficiencies may suggest a decreased capacity to maintain detoxification and metabolic reactions in which glutathione plays a role, resulting in increased free radical stress and/or lipid peroxidation. Drinking too many alcoholic beverages can result in glutathione deficiency. In a study in which 39 healthy men and 130 healthy women between the ages of 20 and 94 were evaluated for glutathione levels, the older subjects had significantly decreased levels (especially in the 60 to 79-year-old group). The authors felt that physical health and longevity were closely related to glutathione levels (Jrnl Lab & Clin Sci 120(5), Nov. 1992: 720-725). Poor nutrition and/or deficiencies in essential micronutrients and many prescription medications may contribute significantly to detoxification capacity in an aged individual. All of these circumstances are common in the elderly. Eating a poor diet that contains too many processed foods without many fruits and vegetables can compromise your body's ability to detoxify pollutants, toxins and other harmful compounds. That can set off metabolic processes capable of fomenting large increases in free radical stress that can accelerate aging. Unfortunately, even in a country as prosperous as our own, nutrient deficiencies are frequent, especially in older citizens. Nutrition Deficiencies A study that looked at what elderly people consumed compared their reported intake with the 1989 Recommended Dietary Amount (RDA) and 1980 RDA: One of four people consumed only two-thirds of the RDA for calories and 60% consumed less than two-thirds of the RDA for vitamin D. As for other nutrients, 50% were found to have inadequate zinc levels (less than two-thirds of the RDA), 31% lacked calcium, 27% were short of vitamin B6, 25% didn't get enough magnesium, 7% missed out on folate and 6% ate less than two-thirds of the requirement for vitamin C (Nutrition Reviews (II), September 1995: S9-S15). When researchers examine what everyone in the U.S. eats, they find that only 9% of Americans consume the recommended five servings of fruits and/or vegetables per day (Proceedings of the National Academy of Sciences, Sept 1993). A diet high in fruits and vegetables is naturally high in antioxidant compounds and is believed to help you live longer. Unfortunately, if you buy your produce in the supermarket, those fruits and vegetables may also be rich in pesticide and herbicide residues (Consumer Reports, March 1999). Obviously, organic produce lacks these residues. But, in any case, research continues to indicate that a diet low in meats and animal fat and high in vegetables protects against antioxidant damage. Longevity Diets A six-year study of 182 people over age 70 in rural Greek villages found that those following their traditional diet of olive oil, whole grain breads, fresh fruits and vegetables and wine were less likely to die during the study than those who consumed more red meat and saturated fat. The most important foods in lowering the risk of early death included fruits, vegetables, legumes (peas and beans), nuts, dairy products and cereals (BMJ 311, 1995: 1457-1460) Another article in Epidemiology highlights the evidence that eating a vegetarian diet increases your chances of living longer. Included in this survey is a recent country-wide study of diet and health in China, showing that the traditional near vegetarian diet of 10% to 15% of calories coming from dietary fat reduced the chances of heart disease, diabetes and many types of cancers. (Epidemiology 3[5], 1992: 389-391). Staying Alive Staying skinny and limiting what you eat may also increase longevity. Scientific studies have previously shown that being overweight can theoretically curtail your life, increasing the risk of heart disease, diabetes and other life-shortening conditions. Animal studies have also shown that restricting food can slow diseases associated with aging. Researchers believe that cutting calories helps your immune system stay younger by reducing the formation of substances that are called proinflammatory cytokines. Specifically reducing your intake of fatty foods may decrease your chance of coming down with autoimmune diseases. Researchers think omega-6 fatty acid vegetable oils (like corn oil) may increase free radical formation and decrease levels of antioxidant enzyme messenger RNA in addition to other effects. (Nutrition Reviews 53[4], 1995: S72-S79). Another study found that cutting calories lowers the levels of oxidative stress and damage, retards age-associated changes and extends maximum life span in mammals (Science 273, July 5, 1996: 59-63). In yet another study, it was shown that caloric restriction early in the life of lab animals increased their life span by a whopping 40% (Australian Family Physician 23[7], July 1994: 1297-1305). Today's modern higher-fat, low-fiber diet with substantial sugar consumption represents everything the longevity researchers say you shouldn't eat. Longevity and Exercise: Exercise may slow aging. When researchers looked at the exercise habits of 17,000 men, average age of 46, they found that those who took part in vigorous activity lived longer. Exercise can improve both cardiac and metabolic functions within the body, while also decreasing heart disease risk. Even modest exercise has been shown to improve cholesterol and blood sugar levels (JAMA 273[15], April 19, 1995: 1179-1184). In a study of how exercise affects your chances of living longer, 9,773 men underwent preventive medicine examinations on two different occasions. When the researchers looked at who lived longest, they found the highest death rate was in men who were unfit during both physical exams. The Treadmill of Life The lowest death rate was in the men who worked out and were in good shape. The researchers concluded that for each minute increase in how long a man could keep treading on a treadmill (between the first and second exam) there was a corresponding 7.9% decrease in the risk of dying. (JAMA 273 [14], April 12, 1995: 1093-1098). Since exercise can increase oxygen consumption up to 10 times, boosting the rate of production of free radicals, researchers believe that older individuals need more antioxidant nutrients to protect them. In a paper published in Aging Clinical and Experimental Research (1997), researchers stated that if you regularly exercise in your golden years, you should take more antioxidant vitamins to compensate for this risk. Longevity Supplementation Melatonin is not often thought of as an antioxidant, but, instead, as a sleep aid. Melatonin, however, is an effective and efficient free radical scavenger and may help stave off the effects of aging. Melatonin protects against what are called hydroxyl free radicals. Research shows that older people's lack of melatonin may make them more susceptible to oxidative stress. In one study, researchers felt that new therapies aimed at stimulating melatonin synthesis may eventually lead to therapies for the prevention of diseases related to premature aging (Aging and Clinical Experimental Research 7[5], 1995: 338-339). Melatonin was shown to provide antioxidant protection in several ways. Toning Down Enzymes Melatonin can ease the effects of enzymes that generate free radicals, enhance the production of glutathione peroxidase (an antioxidant) and defuse the caustic action of free radicals that contain hydroxyls. In several studies, DHEA supplementation has been shown to potentially revive immune function in older adults (Exp. Opin. Invest. Drugs 4[2], 1995: 147-154). In a study of 138 persons older than 85 years compared to 64 persons 20 to 40 years of age, scientists found that the younger people had four times as much DHEA in their bodies. The researchers believe that our bodies make less and less DHEA as we get older. The authors of this study raise the possibility that declining DHEA may be partly to blame for our biological clocks running down (New York Academy of Sciences 1994: 543-552). Vitamins E & C A growing body of research also supports the benefits of taking vitamins E and C to hold off the effects of getting old. Researchers writing in Free Radicals and Aging (1992: 411-418) point out that as you get older your body is home to more and more free radical reactions that may lead to degenerative diseases like heart disease and arthritis. Research has found that in older people with exercise-induced oxidative stress, taking vitamin E every day may significantly fight off free radicals. (To investigate this effect, scientists measured waste products in urine that result from free radical reactions.) Their conclusion: Dietary antioxidants such as vitamin E may be beneficial. Chronological Age Vs. Biological Age Vitamin C also looks to scientists like a good anti-aging bet. Research in the Journal of Advancement in Medicine, (7[1], Spring 1994: 31-41) showed that folks consuming larger amounts of vitamin C were less likely to experience clinical problems at all ages. Those taking in less than 100 mg of vitamin C per day also suffered the most problems. In this research, individuals over 50 years of age who daily consumed the largest amount of vitamin C were as healthy or healthier than the 40 year olds who were taking the least amount of vitamin C. Similar Relationship A similar relationship appears to exist for vitamin E and serum cholesterol levels. In a study of 360 physicians and their spouses, researchers found that people in their 50s who consumed more vitamin E had lower cholesterol than those in their 30s who were taking less. And the longevity beat goes on: In a study evaluating environmental tobacco smoke and oxidative stress, researchers divided 103 people into three groups. Researchers blew smoke at 37 of these folks without protection while 30 of them got to breathe tobacco smoke but took antioxidant supplementation. Another 36 of them merely had to read magazines from doctors' offices. The results: After 60 days of supplementation the antioxidant folks had a 62% reduction in evidence of oxidative damage to their DNA. Cholesterol levels dropped and so did antioxidant enzyme activities. The researchers concluded that taking antioxidants provided a modicum of protection against environmental poisons. The range of antioxidant nutrients used in this study included: beta-carotene, vitamin C, vitamin E, zinc and selenium as well as copper (Cancer Epidemiol Biomarkers Prev 7, November 1998: 981-988). Carotenoids When you mention carotene or carotenoids, most people think of the beta carotene that makes carrots orange. But more than 600 carotenoids are present in colorful vegetables and many of these misunderstood substances are more potent antioxidants than beta-carotene. Carotenoids have been shown to destroy oxygen free radicals in lipids (fats), help protect our cells from the sun's ultra violet radiation and enhance our natural immune response (J. Nutr 119(1), Jan. 1989: 112-115). Some evidence seems to show that how much carotenoids you (and other mammals) have in your cells may be the predominant factor in determining life span (Proc Natl Acad Sci 82 [4], 1985: 798-802). Therefore, a diet rich in carotenoids (leafy green vegetables, carrots, yams, sweet potatoes, squash, citrus fruits and tomatoes) along with supplementation seems to be just what the fountain of youth ordered. Flavonoids Flavonoids, a group of antioxidant plant pigments, seem to be able to protect specific organs. For instance, the flavonoids in milk thistle (Silybum marianum) have been used for ages for liver problems. Bilberry has been found protective for the eye and hawthorn for the heart and circulatory system. Numerous studies have shown the many beneficial effects of flavonoids with perhaps the best known being the ability of anthocyanidins in wine and grape seed extract to help protect your blood vessels and capillaries from oxidative damage (Phytotherapy 42, 1986: 11-14; Am J Clin Nutr 61, 1995: 549-54). Flavonoids are found in vegetables and such fruits as blackberries, blueberries, cherries and grapes. A diet rich in these foods helps ensure an adequate intake of these important nutrient compounds. Amino Acid Health Methionine and cysteine are sulphur containing amino acids (protein building blocks), both of which are essential in maintaining levels of glutathione, a substance that plays a major role in quelling free radicals. Studies have found that as we age, the level of these important amino acids in our bodies decreases. (NEJM 312 [1], 1985: 159-68). As it has been shown that adding cysteine to the diet of test animals can increase their life expectancy considerably, researchers believe these amino acids can help us live longer too. Attitude & Behavior Get more sleep! A recent study showed that men who habitually napped were less likely to have a heart attack. The men in this research who regularly napped for at least 30 minutes per day had about a 30% reduction in heart problems while those who napped for a full hour had a 50% reduction compared to non nappers. Naps of longer duration did not seem to increase the benefit. In the same research, investigators also found that spending time with a pet or merely contemplating nature could also improve cardiac health. Sensuality, optimism and altruism also appeared to have health benefits (Family Practice News, December 15, 1998: 14-15). In another study, this one in American Psychologist, researchers from the University of California found that people who are self-indulgent, pampered and achieve by running roughshod over the competition are less likely to outlive their healthy peers. Being egocentric, impulsive, undependable and tough-minded were predictors of poor physical health and a shorter life. So loosen up and be nice to your fellow humans! (U.C. Davis Magazine, Fall 1995: 14). Longevity at Last While no one has suggested that taking supplements, eating vegetables or exercising can, as of yet, extend the human life span past the generally recognized limit of about 120 years, researchers believe they can improve your odds of living longer. An added benefit: By staying healthier, your old age won't only be longer, it will be more enjoyable, too. And, who knows, if you hang around long enough, taking your nutrients and getting a comfortable amount of consistent exercise, while meditating and refusing to succumb to stress, that magic bullet that will keep you alive for centuries may be discovered. Some day a new antioxidant or other substance may finally prove to provide the elusive fountain of youth. Stay tuned.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=283) Higher Mind - Smart Nutrients for the Performance of a Lifetime...
Date:
June 02, 2005 12:18 PM
Our adult years are the time to reap the fruit of an active, meaningful life – appreciated by family and friends who value our experience and knowledge. For some, however, their later years are clouded by a mental decline that erodes their capacity to enjoy life. More of us are becoming apprehensive about the future health of our minds. Will we still be able to communicate our needs as well as our wisdom? As science focuses its investigative might on the workings of the human brain, new findings suggest that it is possible to enjoy a vital, healthy brain and mind – well into old age. Based on compelling research, Source Naturals formulated HIGHER MIND. It contains the most important Neuroceuticals™ now recognized by nutrition scientists – including phosphatidyl serine, a natural nutrient that promotes cognitive function. The connection is clear: nourish your brain; enrich your life. To have a healthy, well-functioning brain and nervous system, we need the correct nutrients. Our diets must provide the necessary raw materials for nerve cells to grow, for the synthesis of neurochemicals, and for the maintenance of nerve cell membranes. Nutritional deficiencies can alter the brain’s metabolism, which is expressed by changes in perception and thinking, behavior and mood. Brain Cells – Issued at Birth Before birth, neurons (nerve cells) are created at the amazing rate of 15 million per hour. As infants, we have over 100 billion neurons, but this is the most we will ever have because – unlike most other cells in our body – nerve cells do not reproduce. A different strategy is used to replace the neurons that are naturally lost throughout life: nerve cells repair themselves and grow by extending branches of nerve fibers called dendrites (from the Latin word for tree). These are the communication links with other neurons that form the circuitry of the brain. A single neuron may be in contact with up to a hundred thousand others! When the density of this fragile organic communication network decreases, we experience a corresponding decline in mental acuity. Brain Cell Membranes The membrane is the working surface of a cell. It needs to be strong yet flexible, so the cell can maintain its integrity and be able to move and change shape. The membrane regulates the flow of nutrients into the cell and the removal of waste, plus controls the passage of molecular messages from outside the cell to its interior. Membrane ion pumps use a third of the cell’s energy just to maintain the correct ratio of sodium to potassium. In neurons, a rapid exchange of sodium and potassium ions across the nerve membrane is responsible for their unique ability to generate the electrical impulses that are the basis of all communication in the nervous system. As cells age, their membranes become less fluid and more rigid. Key membrane molecules called phospholipids are crucial to the health of neuron membranes, allowing the brain to maintain its youthful quality. The phospholipids in HIGHER MIND – especially phosphatidyl serine and phosphatidyl choline – are essential nutritional supplements for the aging brain. Phosphatidyl Serine – Key to Cognition For the past decade, researchers have been investigating the role in brain health of a remarkable neuroceutical, phosphatidyl serine (PS). This key structural molecule is integral to the matrix of fats and proteins that compose cell membranes. Although PS is found in all the cells of the body, its highest concentration is in nerve cell membranes. PS is rarely found in the foods we eat, so the body has to synthesize it, but the process is energy- intensive and becomes less efficient with age. Consequently, our levels of PS tend to decline as we get older. PS taken as a dietary supplement is well-absorbed, readily reaching the brain, where it helps create more effective, well-structured nerve cell membranes. The positive effects of PS supplementation have been demonstrated by 23 clinical studies with over 1200 human subjects, ages 43 to 90. Consistent and statistically significant results have confirmed the value of PS in improving age-related cognitive decline, as well as in improving behavioral aspects such as apathy and withdrawal.1 A major study concluded that for one particular measurable parameter of higher mental functions, PS recipients achieved scores of persons roughly 12 years younger.2 Nerve Growth Factor (NGF) is one of the most important proteins the body makes. It enables neurons to extend dendrites out to other neurons, allowing the brain to maintain an effective communication network. In experiments, PS enhanced the production and reception of NGF, which tend to drop off radically with age.3 The effects of PS at the cellular level are manifest in the performance of the brain as a whole. Subjects taking PS showed increased levels of brain energy metabolism. This enhancement corresponded to higher performances on cognitive tests.4 The Chemistry of Thought Science now understands the role of neurotransmitters in regulating the body’s complex network of behavior. Neurotransmitters are the chemicals used by neurons to communicate with each other. Activated by a neuron’s electrical impulse, neurotransmitters travel between nerve cells, where they excite or inhibit (in various degrees) the electrical impulse in neighboring cells. One of HIGHER MIND’S key strategies is to improve the brain’s ability to produce and use acetylcholine, a key excitatory neurotransmitter. Acetylcholine is essential for both the storage and recall of memory, and partly responsible for concentration and focus. It also plays a significant role in muscular coordination. Patients showing cognitive decline may exhibit reduced ability to synthesize and utilize acetylcholine.5 The chemical building blocks of acetylcholine and other neurotransmitters are called precursors. The most important one for acetylcholine is DMAE (dimethylaminoethanol). This natural substance is found in various fish, such as anchovies and sardines. Supplements of DMAE (and phosphatidyl choline) promote increased levels of choline in the brain. Acetylcholine is created when an acetyl group is attached to the choline molecule, with the help of choline acetyl transferase (CAT), a key brain enzyme. Acetyl L-carnitine is an amino acid that activates this enzyme. Acetyl L-carnitine may also help reduce lipofuscin deposits in the brain because of its involvement in the metabolism of fatty acids.6 Lipofuscin is composed of oxidized fats and proteins; the brown “age spots” on the back of an elderly person’s hand are made of lipofuscin. The amino acid L-pyroglutamic acid sensitizes the acetylcholine receptor sites on a neuron membrane. A given amount of acetylcholine will then have a larger, more powerful effect. Studies have shown that supplements of L-pyroglutamic acid seem to enhance the ability to focus, remember, and learn. Total Nutrition for the Brain The neurotransmitters dopamine and noradrenalin are critical to motor coordination, motivation, concentration, and alertness. Like acetylcholine, their production tends to decline with age. The precursors and activators of dopamine and noradrenalin included in HIGHER MIND are the amino acids N-Acetyl L-Tyrosine and DL-phenylalanine (DLPA), plus folic acid, vitamins B-3, B-6, and C. DLPA is also a precursor to PEA, a neuroamine that has a stimulating effect on the brain. Glutamine is an amino acid precursor to glutamic acid, a major excitatory neurotransmitter involved in mental activity and learning. Glutamine acts as an alternative fuel source for the brain when blood sugar levels are low. It also helps the brain dispose of waste ammonia, which is a natural result of protein breakdown but is irritating to neurons even at low levels. GABA is a dietary amino acid which is also an inhibitory neurotransmitter. GABA works to calm and balance the mind, enhancing mental focus. Along with taurine, these two relaxing neurotransmitters provide a balancing influence to the other, excitatory neurotransmitters. Taurine is found in brain tissue more than anywhere else in the body. It has antioxidant properties and serves as a nerve cell membrane stabilizer, preventing excessive or erratic electrical activity in the brain. The Importance of Magnesium Magnesium must be present in adequate amounts in the synaptic gaps between neurons or the neurons become hyper-reactive: causing noises to sound excessively loud and emotional reactions to be extreme. Magnesium also activates a key enzyme responsible for maintaining cellular sodium- potassium balance, which is absolutely essential to the electrical activity of nerve cells, as well as to the existence of the cell itself. (Cells would burst if the sodium-potassium ratio were wrong.) Magnesium also helps relax cerebral blood vessels and is important to the manufacture of ATP, the chief energy molecule of the brain. A buildup of aluminum has been found in the brains of some elderly. In 1989, the British medical journal Lancet published a study showing that drinking water with aluminum can increase the risk of damage by up to 50%. An abundant natural element, aluminum is now a common feature in our culture. It’s found in tap water, cookware, deodorants, beverage containers, baked goods, and of course as aluminum foil. In the brain, aluminum breaks down the structure of neurons – causing them to starve – by displacing magnesium from tubulin, a glycoprotein responsible for making microtubules. These tiny pipe-like structures within a neuron provide needed rigidity, as well as transport nutrients from the nucleus down the dendrites to the ends of the nerve cell. Magnesium malate is an excellent form of magnesium that ensures neurons receive this vital mineral. B is for Brain Vitamins HIGHER MIND also contains a high profile of B vitamins and other key nutrients that are often N A T U R A L S S O U R C E Strategies for Wellness SM ¤ lacking in older individuals. A deficiency in any of the B vitamins can alter nerve function and psychological well-being. Thiamine (B-1), known as the “nerve vitamin,” was first recognized because its deficiency caused beriberi, a degenerative nerve disease. Thiamine is part of the structure of nerve cell membranes and is important to the reparative process that neurons need to offset the stress of continual firing of the electrical impulse. Low amounts of thiamine can cause cell malnutrition in the hypothalamus, the brain’s memory center. 7 NAD and NADH, two coenzyme forms of Niacin (B-3), are the most plentiful coenzymes in the brain. They are essential to hundreds of enzymatic reactions, including ones that produce energy. NADH can stimulate the synthesis of key mood-elevating neurotransmitters. It is also one of the body’s most potent antioxidants. Pantothenic acid (B-5), cyanocobalamin (B-12), and folic acid are required to form the myelin sheath – the insulating covering of nerve fibers. A diet low in pantothenic acid has been shown to make test subjects emotionally upset, irritable, and depressed.7 A lack of B-12 can result in poor concentration and, in severe deficiencies, hallucinations. Pyridoxine (B-6) is precursor to over 60 enzymatic reactions and is involved in the synthesis of several neurotransmitters. Brain Power Brain cells almost exclusively burn glucose for their energy (other cells can also burn fat), and typically require 50% of all the glucose in the blood. Two B-like vitamins help in the utilization of glucose: PAK (pyridoxine alpha-ketoglutarate) may potentiate the effects of insulin and improve glucose utilization to the cells;8 Biotin is important for the transformation of glucose into energy in the brain. Lipoic acid and coenzyme Q10 are metabolic energizers that help produce ATP, the primary energy molecule in the body. Since the brain uses 20% of the body’s total energy supply, efficient ATP production is vital. Lipoic acid and CoQ10 are also powerful antioxidants that help regenerate other antioxidants in the body. The blood vessels feeding the brain become less efficient as we pass middle age. Since the brain depends on the bloodstream to deliver nutrients and oxygen and to remove waste, the quality of this blood flow is paramount to proper brain nutrition. Ginkgo biloba leaf extract has been shown in scientific studies to increase blood flow to the brain by helping vessels to dilate. It also promotes the smoothness and healthy integrity of blood vessel linings. For the Life of Your Mind Without proper nutrition, the brain will deteriorate; therefore strategies are needed to both enhance current brain function and protect it throughout life. Based on the latest scientific findings, Source Naturals HIGHER MIND is formulated with neuroceuticals that support the mental functions that tend to decline with age. They give your brain the nourishment it needs to integrate perception, memory, and learning into a more comprehensive awareness – so you can excel for a lifetime.
References
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=156) CALCIUM D-GLUCARATE - Estrogen Detoxification 
Date:
June 01, 2005 09:25 AM
From the womb to the tomb, we are subject to the effects of estrogen, the potent female hormone that shapes our lives. Variations in estrogen levels can have a dramatic effect on our cellular development. Source Naturals is proud to introduce a nutrient that may help the body remove excess estrogen, thereby giving relief to estrogen-sensitive tissues. Calcium D-glucarate is currently the subject of numerous clinical studies. It is proving to have great potential for addressing health concerns closest to our heart. One of life’s most delicate balancing acts is found in the ebb and flow of hormones that is constantly taking place in the human body. These messenger chemicals are fundamental to the process of life. Produced by endocrine glands, hormones travel throughout the body, communicating with each other as they direct cellular activity. For example, the hypothalamus gland monitors hormone levels in the body. It signals the pituitary gland, advising it to send messages to the ovaries to either produce or stop producing estrogen. Estrogen is an extremely powerful hormone whose activity can be measured in parts per trillion. Therefore, it doesn’t take much to create an imbalance. Like all hormones, estrogen communicates with a cell by docking to a particular receptor site on that cell’s membrane. If there is an excess of these estrogen-sensitive receptors, or an excess of circulating estrogen in the bloodstream, normal cellular metabolism can be altered. Another problem is that estrogen receptors are not very particular; they will accept many chemicals – both natural and synthetic – other than estrogen. How the body removes excess estrogen One of the processes by which estrogen and estrogenic compounds are metabolized and broken down is through glucuronidation. In the liver, they’re bound to glucuronic acid and then excreted in the urine or feces. This process can be disrupted by an enzyme called beta-glucuronidase, which is found in the gastro- intestinal tract. It frees the bound-up estrogen or estrogenic compound, releasing it to be reabsorbed back into the bloodstream – to again affect cells. Obviously estrogen is needed by the body; however, too much can lead to cellular disruption. Since it can be very difficult to avoid the estrogenic chemicals rampant in our environment, another strategy is needed, and that is to reduce their negative effects by supporting the body’s natural ability to remove excess estrogen and other hormones and toxins. Calcium D-glucarate and hormone metabolism The removal of excess estrogen can be increased by a natural substance called Calcium D-glucarate (CDG), because it inhibits beta-glucuronidase activity in the body. This means that estrogen bound for excretion stays bound, and the total estrogen load on the body is reduced. In clinical trials, tissues that are sensitive to excess hormones – such as breast, liver, and lung – have been shown to respond favorably to CDG. In addition to estrogen and estrogenic compounds, CDG helps promote excretion of other hormone metabolites as well as cellular toxins and steroids. CDG is made naturally in small quantities in the body; it is also found in a variety of fruits and vegetables: oranges, broccoli, carrots, spinach, and apples. Vitamin A has been shown to have a synergistic effect with CDG. One 500 mg tablet of Source Naturals CALCIUM D-GLUCARATE is equivalent to the phytonutrient activity found in 82 pounds of fresh fruits and vegetables. The suggested use for preventative health maintenance is 3 to 4.5 grams per day. No toxicity has been found with its usage. Phytonutrients also help reduce estrogen exposure Another strategy to reduce the effects of excess estrogen is to increase the intake of plant estrogens. This helps for two reasons. First, by occupying estrogen receptor sites, these natural estrogenic compounds block synthetic estrogens from attaching to these sites. Second, phytoestrogens only mildly activate receptors. One of the best phytoestrogens is genistein, the isoflavone in soybeans responsible for soy’s beneficial influence on the human body. Increased intake of genistein and/or soy is being recommended by many health professionals, especially for post-menopausal women. Please see Source Naturals product literature on GENISTEIN as well as MENOBALANCE, our nutritional menopause formula with genistein and black cohosh. Both are part of our advanced line of nutritional support for women As new research sheds light on the importance of proper hormone balance to our health, it’s vital to protect ourselves from the increased burden of estrogen that we are encountering today. Source Naturals CALCIUM D-GLUCARATE is a timely nutrient that can make a real difference in our lives.
References
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=126) | ||||||||||||
Read More
What is thyroid glands.jpg )
Importance of selenium
