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What Are The Magnesium Malate Benefits? Darrell Miller 5/17/13
Magnesium Malate Benefits Darrell Miller 1/30/13
Magnesium Malate - Fight Aluminum Build-Up ... Darrell Miller 6/3/05
Higher Mind - Smart Nutrients for the Performance of a Lifetime... Darrell Miller 6/2/05



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What Are The Magnesium Malate Benefits?
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Date: May 17, 2013 10:59 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Are The magnesium malate Benefits?

magmalatemolicule

A combo Mineral:

magnesium malate is a combination of Malic acid and magnesium. Both compounds come together to form a powerful supplement that is crucial for the body. Magnesium is used in more than 300 processes in the body making it one of the most needed minerals in the body. It is also found in the bones mostly and is synthesized from the locations to aid in optimizing many bodily functions.

Malic acid is an organic ingredient mostly found in the fruits. The compound combines with compounds forming salts known as Malates. The combination of Malic acid and magnesium forms magnesium malate which is an important compound when it comes to the generation cellular energy. It is also important when it comes to a variety of physical and muscular conditions. The compound also comes in handy to treat a number of conditions in the body when used as a supplement.

These include;

Constipation

If you are suffering from constipation, this is one to go. It is commonly used to loosen stools and induce laxative actions to clean the system. It is a perfect detox agent and is famously used in colonoscopy and bowel surgery. The Malic part of the compound is ideal for the laxative action giving relief to anyone suffering from constipation. The combination of the two compounds enhances these effects making them more potent in effectiveness.

Fibromyalgia Pain Relief

This compound is used to induce relief on patients suffering fro fibromyalgia. This condition will often cause muscle stiffness, muscoskeletal pain and chronic severe pains. These supplements are used to exponentially reduce the effects that come with the disorder. A study was done and published in the Journal of Nutritional Medicine where 15 patients were placed under observation with the treatment. All patients reported increased comfort when using the supplements in relation to fibromyalgia symptoms.

Solving Syndromes of chronic fatigue

magnesium malate enhances the production of energy at a cellular level increasing the condition of the individual using it. The process eliminates the chronic Fatigue syndrome and its effects allowing the individual to enjoy a wholesome life. This also deals with any accumulated stress and distraction factors that come with a tired out body. A rejuvenated body enhances performance in all aspects of life making this product one major energy and performance booster in the long run.

Other ailments

The combination can also be used to target heart related disease reducing the risk of experiencing closed valves and blood vessels. It is used to treat heart related diseases in the hospitals. Magnesium is also ideal when it comes to dealing with skin breakouts ranging from boils to skin ulcers. The compound will target many functions of the body through a domino effect. No matter how minute the effect may be on a general sense, it is important for the running of the boy functions such as the heart, nervous system and the epidermal system. The compound is one of the most widely used supplements from a varied number of conditions producing great results.

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Magnesium Malate Benefits
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Date: January 30, 2013 12:54 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: magnesium malate Benefits

The compound magnesium malate was discovered by combining malic acid with magnesium. Malic acid is a naturally occurring element that aids in the generation of energy during aerobic as well as anaerobic activities while, magnesium is the fifth most abundant mineral found in the human body, which is vital for the health of the kidneys, bones and heart.

Malic acid and magnesium together offers several health related benefits. It helps to control numerous essential biological functions in the body such as the formation of nerves and muscle. It is naturally found in bananas, yogurt, fish, artichokes, almonds, grains, black beans, cashews and other nuts.

Health Benefits Of magnesium malate:

The malic acid present in magnesium malate attaches itself to the aluminum content of the body and helps to eliminate it. This allows the growth and detoxification of healthy nerve cells. magnesium malate also assists in loosening stools due to its laxative properties so; it is used to treat constipation effectively. Physicians or technicians also use it as a cleansing agent prior to a bowel surgery or colonoscopy. This vital compound is known to relax muscles therefore; it is often utilized to treat uterine cramping, headaches and several other general muscle discomforts.

As per medical research, people who do not receive adequate magnesium through their diet usually stand the risk of kidney stone formation however; they can prevent this condition by consuming magnesium malate. This important compound also aids to synthesize adenosine triphosphate or ATP - a nucleotide that aids to store energy in the tissues of muscles and converts it into cellular energy source. This energy generating properties are useful in treating chronic fatigue syndrome and fibromyalgia.

magnesium malate also encourages the production of saliva, which in turn controls oral bacteria. Moreover, due to its antiseptic properties, it is also used in mouthwash and toothpaste.

Studies have found that 70% or more of the American population is deficient in magnesium, magnesium malate taken daily is a good way for anybody to get more dietary magnesium. Magnesium is involved in over 300 enzyme processes in the body, if you are deficient in magnesium, these enzyme processes that maintain the body will fail and your health can decline. Consider taking magnesium in the form of magnesium malate. Have you had your magnesium today?

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Magnesium Malate - Fight Aluminum Build-Up ...
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Date: June 03, 2005 11:44 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: magnesium malate - Fight Aluminum Build-Up ...

magnesium malate

ALUMINUM has been the focus of much negative attention lately– numerous studies have indicated that aluminum accumulates in the body, especially in nerve tissues, potentially causing harm. Recently, scientific researchers have discovered that one compound may have the powerful effect of diminishing this unwanted aluminum accumulation. On the cutting edge of nutrition science, Source Naturals is one of the first companies to introduce this powerfully protective compound: magnesium malate.

THE DANGERS OF ALUMINUM

Aluminum is a naturally occurring metal. It has been the subject of recent studies on aging, and some scientists consider it to be harmful. It may come as a surprise that aluminum can be found in a wide variety of foods and manufactured products, such as baking powder, non-dairy creamers, antacids, deodorants, cookware, and food containers. Even tap water contains aluminum. With so many possible avenues for ingesting aluminum, we may be consuming more than nature originally intended. Mounting evidence that aluminum tends to accumulate in the body is even more cause for alarm. Unfortunately, there are no overt warning signs of excess aluminum accumulation, until levels become high enough to have adverse effects on health.

THE ALUMINUM-MAGNESIUM LINK

Researchers have suggested that aluminum may be more likely to accumulate in the brains of persons whose diets are Magnesium-deficient — which, unfortunately, includes 90% of Americans! Several studies have shown that animals fed diets low in Magnesium accumulate high concentrations of aluminum in the Central Nervous System. One of Magnesium’s many functions is to activate the enzyme tubulin involved in the maintenance of nerve tissue cells. It has been suggested that when there is not enough Magnesium in the body to plug into the appropriate receptor site on the tubulin enzyme, aluminum takes its place instead. This leads to the inactivation of tubulin and, consequently, inadequate nerve function. Because a Magnesium-deficient diet may increase the amount of aluminum taken up and stored by the body, it is vitally important that we take in sufficient amounts.

magnesium malate — A ONE-TWO PUNCH

magnesium malate supplies a one-two punch in combating excess aluminum accumulation. In addition to providing 45% of the U.S. R.D.A. for Magnesium, magnesium malate also supplies Malic Acid. Found abundantly in fruits such as apples, Malic Acid is also produced in the human body. It is a metabolite of the Krebs cycle, the set of biochemical reactions used to produce 90% of all energy in the cells of the body. Malic Acid readily crosses the Blood-Brain-Barrier and has been shown to bind to aluminum. It functions in the body by drawing aluminum away from the tubulin enzyme, so that Magnesium can plug into the receptor sites instead. Malic Acid’s unique ability to bind with aluminum means it can be flushed out of the body, preventing unwanted build-up.

THE PRO-ACTIVE APPROACH

With all of the negative evidence mounting against aluminum, educated consumers will want to take precautions in order to maintain their health and well being. Of course, the best way to avoid excess aluminum is to cut back on aluminum intake from known sources. Use only stainless steel or cast iron cookware, and look for aluminum- free deodorants and antacids. Always use filtered or spring water for drinking and cooking. And for those who want to take a pro-active approach, adding magnesium malate to your supplement regimen may be your best bet in depleting unwanted aluminum build-up in the body.

References

1. Mitani, K. 1992 “Relationship between...aluminum load...and magnesium status.”Magnesium Research 5(3):203-13
2. Yoshida, S. 1991 “Environmental factors in western Pacific foci...role of Aluminum(Al)...” Rinsho Shinkeigaku 31(12):1310-2
3. Costello, RB.; Moser-Veillon, PB. 1992 “A review of magnesium intake...” Magnesium Research 5(1):61-7
4. Yasui, M; Yase, Y; Ota, K; Garruto, RM. 1991 “Aluminum deposition... from the Kii Peninsula of Japan.” Neurotoxicology 12(3):615-20



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Higher Mind - Smart Nutrients for the Performance of a Lifetime...
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Date: June 02, 2005 12:18 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Higher Mind - Smart Nutrients for the Performance of a Lifetime...

Our adult years are the time to reap the fruit of an active, meaningful life – appreciated by family and friends who value our experience and knowledge. For some, however, their later years are clouded by a mental decline that erodes their capacity to enjoy life. More of us are becoming apprehensive about the future health of our minds. Will we still be able to communicate our needs as well as our wisdom? As science focuses its investigative might on the workings of the human brain, new findings suggest that it is possible to enjoy a vital, healthy brain and mind – well into old age. Based on compelling research, Source Naturals formulated HIGHER MIND. It contains the most important Neuroceuticals™ now recognized by nutrition scientists – including phosphatidyl serine, a natural nutrient that promotes cognitive function. The connection is clear: nourish your brain; enrich your life.

To have a healthy, well-functioning brain and nervous system, we need the correct nutrients. Our diets must provide the necessary raw materials for nerve cells to grow, for the synthesis of neurochemicals, and for the maintenance of nerve cell membranes. Nutritional deficiencies can alter the brain’s metabolism, which is expressed by changes in perception and thinking, behavior and mood.

Brain Cells – Issued at Birth

Before birth, neurons (nerve cells) are created at the amazing rate of 15 million per hour. As infants, we have over 100 billion neurons, but this is the most we will ever have because – unlike most other cells in our body – nerve cells do not reproduce. A different strategy is used to replace the neurons that are naturally lost throughout life: nerve cells repair themselves and grow by extending branches of nerve fibers called dendrites (from the Latin word for tree). These are the communication links with other neurons that form the circuitry of the brain. A single neuron may be in contact with up to a hundred thousand others! When the density of this fragile organic communication network decreases, we experience a corresponding decline in mental acuity.

Brain Cell Membranes

The membrane is the working surface of a cell. It needs to be strong yet flexible, so the cell can maintain its integrity and be able to move and change shape. The membrane regulates the flow of nutrients into the cell and the removal of waste, plus controls the passage of molecular messages from outside the cell to its interior. Membrane ion pumps use a third of the cell’s energy just to maintain the correct ratio of sodium to potassium. In neurons, a rapid exchange of sodium and potassium ions across the nerve membrane is responsible for their unique ability to generate the electrical impulses that are the basis of all communication in the nervous system. As cells age, their membranes become less fluid and more rigid. Key membrane molecules called phospholipids are crucial to the health of neuron membranes, allowing the brain to maintain its youthful quality. The phospholipids in HIGHER MIND – especially phosphatidyl serine and phosphatidyl choline – are essential nutritional supplements for the aging brain.

Phosphatidyl Serine – Key to Cognition

For the past decade, researchers have been investigating the role in brain health of a remarkable neuroceutical, phosphatidyl serine (PS). This key structural molecule is integral to the matrix of fats and proteins that compose cell membranes. Although PS is found in all the cells of the body, its highest concentration is in nerve cell membranes. PS is rarely found in the foods we eat, so the body has to synthesize it, but the process is energy- intensive and becomes less efficient with age. Consequently, our levels of PS tend to decline as we get older. PS taken as a dietary supplement is well-absorbed, readily reaching the brain, where it helps create more effective, well-structured nerve cell membranes. The positive effects of PS supplementation have been demonstrated by 23 clinical studies with over 1200 human subjects, ages 43 to 90. Consistent and statistically significant results have confirmed the value of PS in improving age-related cognitive decline, as well as in improving behavioral aspects such as apathy and withdrawal.1 A major study concluded that for one particular measurable parameter of higher mental functions, PS recipients achieved scores of persons roughly 12 years younger.2 Nerve Growth Factor (NGF) is one of the most important proteins the body makes. It enables neurons to extend dendrites out to other neurons, allowing the brain to maintain an effective communication network. In experiments, PS enhanced the production and reception of NGF, which tend to drop off radically with age.3 The effects of PS at the cellular level are manifest in the performance of the brain as a whole. Subjects taking PS showed increased levels of brain energy metabolism. This enhancement corresponded to higher performances on cognitive tests.4

The Chemistry of Thought

Science now understands the role of neurotransmitters in regulating the body’s complex network of behavior. Neurotransmitters are the chemicals used by neurons to communicate with each other. Activated by a neuron’s electrical impulse, neurotransmitters travel between nerve cells, where they excite or inhibit (in various degrees) the electrical impulse in neighboring cells. One of HIGHER MIND’S key strategies is to improve the brain’s ability to produce and use acetylcholine, a key excitatory neurotransmitter. Acetylcholine is essential for both the storage and recall of memory, and partly responsible for concentration and focus. It also plays a significant role in muscular coordination. Patients showing cognitive decline may exhibit reduced ability to synthesize and utilize acetylcholine.5 The chemical building blocks of acetylcholine and other neurotransmitters are called precursors. The most important one for acetylcholine is DMAE (dimethylaminoethanol). This natural substance is found in various fish, such as anchovies and sardines. Supplements of DMAE (and phosphatidyl choline) promote increased levels of choline in the brain. Acetylcholine is created when an acetyl group is attached to the choline molecule, with the help of choline acetyl transferase (CAT), a key brain enzyme. Acetyl L-carnitine is an amino acid that activates this enzyme. Acetyl L-carnitine may also help reduce lipofuscin deposits in the brain because of its involvement in the metabolism of fatty acids.6 Lipofuscin is composed of oxidized fats and proteins; the brown “age spots” on the back of an elderly person’s hand are made of lipofuscin. The amino acid L-pyroglutamic acid sensitizes the acetylcholine receptor sites on a neuron membrane. A given amount of acetylcholine will then have a larger, more powerful effect. Studies have shown that supplements of L-pyroglutamic acid seem to enhance the ability to focus, remember, and learn.

Total Nutrition for the Brain

The neurotransmitters dopamine and noradrenalin are critical to motor coordination, motivation, concentration, and alertness. Like acetylcholine, their production tends to decline with age. The precursors and activators of dopamine and noradrenalin included in HIGHER MIND are the amino acids N-Acetyl L-Tyrosine and DL-phenylalanine (DLPA), plus folic acid, vitamins B-3, B-6, and C. DLPA is also a precursor to PEA, a neuroamine that has a stimulating effect on the brain. Glutamine is an amino acid precursor to glutamic acid, a major excitatory neurotransmitter involved in mental activity and learning. Glutamine acts as an alternative fuel source for the brain when blood sugar levels are low. It also helps the brain dispose of waste ammonia, which is a natural result of protein breakdown but is irritating to neurons even at low levels. GABA is a dietary amino acid which is also an inhibitory neurotransmitter. GABA works to calm and balance the mind, enhancing mental focus. Along with taurine, these two relaxing neurotransmitters provide a balancing influence to the other, excitatory neurotransmitters. Taurine is found in brain tissue more than anywhere else in the body. It has antioxidant properties and serves as a nerve cell membrane stabilizer, preventing excessive or erratic electrical activity in the brain.

The Importance of Magnesium

Magnesium must be present in adequate amounts in the synaptic gaps between neurons or the neurons become hyper-reactive: causing noises to sound excessively loud and emotional reactions to be extreme. Magnesium also activates a key enzyme responsible for maintaining cellular sodium- potassium balance, which is absolutely essential to the electrical activity of nerve cells, as well as to the existence of the cell itself. (Cells would burst if the sodium-potassium ratio were wrong.) Magnesium also helps relax cerebral blood vessels and is important to the manufacture of ATP, the chief energy molecule of the brain. A buildup of aluminum has been found in the brains of some elderly. In 1989, the British medical journal Lancet published a study showing that drinking water with aluminum can increase the risk of damage by up to 50%. An abundant natural element, aluminum is now a common feature in our culture. It’s found in tap water, cookware, deodorants, beverage containers, baked goods, and of course as aluminum foil. In the brain, aluminum breaks down the structure of neurons – causing them to starve – by displacing magnesium from tubulin, a glycoprotein responsible for making microtubules. These tiny pipe-like structures within a neuron provide needed rigidity, as well as transport nutrients from the nucleus down the dendrites to the ends of the nerve cell. magnesium malate is an excellent form of magnesium that ensures neurons receive this vital mineral.

B is for Brain Vitamins

HIGHER MIND also contains a high profile of B vitamins and other key nutrients that are often N A T U R A L S S O U R C E Strategies for Wellness SM ¤ lacking in older individuals. A deficiency in any of the B vitamins can alter nerve function and psychological well-being. Thiamine (B-1), known as the “nerve vitamin,” was first recognized because its deficiency caused beriberi, a degenerative nerve disease. Thiamine is part of the structure of nerve cell membranes and is important to the reparative process that neurons need to offset the stress of continual firing of the electrical impulse. Low amounts of thiamine can cause cell malnutrition in the hypothalamus, the brain’s memory center. 7 NAD and NADH, two coenzyme forms of Niacin (B-3), are the most plentiful coenzymes in the brain. They are essential to hundreds of enzymatic reactions, including ones that produce energy. NADH can stimulate the synthesis of key mood-elevating neurotransmitters. It is also one of the body’s most potent antioxidants. Pantothenic acid (B-5), cyanocobalamin (B-12), and folic acid are required to form the myelin sheath – the insulating covering of nerve fibers. A diet low in pantothenic acid has been shown to make test subjects emotionally upset, irritable, and depressed.7 A lack of B-12 can result in poor concentration and, in severe deficiencies, hallucinations. Pyridoxine (B-6) is precursor to over 60 enzymatic reactions and is involved in the synthesis of several neurotransmitters.

Brain Power

Brain cells almost exclusively burn glucose for their energy (other cells can also burn fat), and typically require 50% of all the glucose in the blood. Two B-like vitamins help in the utilization of glucose: PAK (pyridoxine alpha-ketoglutarate) may potentiate the effects of insulin and improve glucose utilization to the cells;8 Biotin is important for the transformation of glucose into energy in the brain. Lipoic acid and coenzyme Q10 are metabolic energizers that help produce ATP, the primary energy molecule in the body. Since the brain uses 20% of the body’s total energy supply, efficient ATP production is vital. Lipoic acid and CoQ10 are also powerful antioxidants that help regenerate other antioxidants in the body. The blood vessels feeding the brain become less efficient as we pass middle age. Since the brain depends on the bloodstream to deliver nutrients and oxygen and to remove waste, the quality of this blood flow is paramount to proper brain nutrition. Ginkgo biloba leaf extract has been shown in scientific studies to increase blood flow to the brain by helping vessels to dilate. It also promotes the smoothness and healthy integrity of blood vessel linings.

For the Life of Your Mind Without proper nutrition, the brain will deteriorate; therefore strategies are needed to both enhance current brain function and protect it throughout life. Based on the latest scientific findings, Source Naturals HIGHER MIND is formulated with neuroceuticals that support the mental functions that tend to decline with age. They give your brain the nourishment it needs to integrate perception, memory, and learning into a more comprehensive awareness – so you can excel for a lifetime.

References
1. Palmieri, G., et al. (1987). Clin. Trials J. 24: 73- 83.
2. Crook, T.H., et al. (1991). Neurol. 41: 644-49.
3. Nunzi, M.G., et al. In Phospholipids: Biochemical, Pharmaceutical and Analytical Considerations (ed. I. Hanin and G. Pepeu).
New York: Plenum Press, 1990.
4. Heiss, W.D., et al. (1993). Annals N.Y. Acad. Sci. 695: 327-31.
5. Passeri, M., et al. (1990). Int. J. Clin. Pharm. Res. X(1/2): 75-79.
6. Kohjimoto, Y., et al. (1988). Japanese Journal of Pharmacology 48(3): 365-71.
7. Philpott, William H. Brain Allergies: the Psychonutrient Connection. New Canaan: Keats, 1987.
8. Passariello, N., et al. (1983). Int. J. Clin. Pharmacol. Ther. Toxicol. 21: 252-56.



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