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The Many Benefits of Chromium Amino Acid Chelate
Date:
November 08, 2022 11:58 AM
Though it may not be a household name, chromium is a essential trace mineral with a wide range of benefits. Perhaps most importantly, chromium helps to maintain normal blood sugar levels. Additionally, chromium supports cholesterol levels already in the normal range, and enhances the effectiveness of insulin. In other words, this essential mineral helps your body to burn glucose for fuel. With so many benefits, it's no wonder that chromium supplements are becoming increasingly popular. Read on to learn more about this essential mineral, and how it can improve your health. What is Chromium? As we mentioned above, chromium is a trace element, which means that our bodies require only very small amounts of it in order to function properly. Though we only need small amounts, chromium plays an important role in regulating blood sugar levels and supporting healthy cholesterol levels. Chromium is found naturally in many foods, such as broccoli, grape juice, whole grains, potatoes, meat, and poultry. However, due to modern-day farming practices and processing methods, the level of chromium in these foods has decreased significantly over the years. This means that even if you're eating a healthy diet, you may not be getting enough chromium. And that's where supplements come in. Benefits of Chromium Supplements Chromium supplements are an easy and convenient way to make sure you're getting enough of this essential mineral. Chromium supplements have been shown to improve blood sugar control in people with diabetes, as well as reduce “Bad” LDL cholesterol and triglyceride levels in people with high cholesterol. Additionally, chromium supplements can help with weight loss by reducing food cravings and increasing feelings of fullness after meals. If you're struggling to lose weight or control your blood sugar levels, adding a chromium supplement to your daily routine may be just what you need. In Summary: Chromium is an essential trace element with many important health benefits. If you're not getting enough chromium from your diet, consider taking a supplement. Chromium supplements can help to regulate blood sugar levels and support healthy cholesterol levels. Additionally, they may also help with weight loss by reducing food cravings and increasing feelings of fullness after meals. Talk to your doctor about whether or not achromium supplement is right for you.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6561) Pumpkin seeds, mostly eaten during Halloween, contain an impressivearray of vitamins and minerals that support heart health
Date:
September 15, 2018 08:52 AM
Why You Should Be Eating a Handful of Pumpkin Seeds Everyday. You can eat pumpkin seeds raw, toasted and spiced, or salted and in their shell. ... Pumpkin seeds are loaded with vitamins and minerals, including vitamins B, E, and K, magnesium, and iron.these seeds are consumed during hallowen they are usually scraped out of the pumpkin in making jack-o-lanterns. They are rich in essential fatty acids and tryptophan, which make them an effective tool in improving heart health and preventing diseases, such as arthritis, osteoporosis, bladder dysfunction, and anxiety.To support heart health, pumpkin seeds work by increasing high-density lipoprotein while decreasing low-density lipoprotein or “bad” cholesterol levels.Pumpkin seeds are good for the bones because of their high magnesium, phosphorus, and zinc content. In addition, pumpkin seed oil helps relieve inflammation linked to arthritis and related conditions.Another benefit of pumpkin seeds has to do with bladder health. Up to 16 percent of aging adults are affected by overactive bladder, which can greatly affect their quality of life. An overactive bladder causes sudden urges to urinate and can cause involuntary urination. Recent study by researchers from the University of Tennesse have shown that pumpkin seed oil and extract are effective in improving these symptoms and helping to bring back bladder control,the high tryptophan content of pumpkin seeds help improve anxiety. In the brain and also improve mood. Key Takeaways:
"However, these nutty seeds and their byproduct pumpkin seed oil should be consumed more often because they contain a variety of vitamins and minerals that are good for the heart." Read more: https://www.naturalnews.com/2018-08-16-pumpkin-seeds-vitamins-and-minerals-heart-health.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5764) Joan Salge Blake: Can An Apple A Day Keep Your Cardiologist At Bay?
Date:
November 14, 2016 02:49 PM
Seems there is some truth to that old saying “an apple a day keeps the doctor away.” If that doctor is a cardiologist it seems there just may be truth there. Apples have many components that indeed work to keep your heart healthy and may help lower bad cholesterol. Apples may even help lower high blood pressure and slim your waistline. Key Takeaways:
"Apples are a low-calorie, rich source of fiber, phytochemicals, and potassium, all of which can keep your heart healthy." Reference:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3443) How Do Probiotics Boost Your Immune System?
Date:
August 28, 2015 10:21 PM
An average person carries thousands of microorganisms. Among these microorganisms are bacteria. For most of us, the word bacteria usually comes with a negative connotation. It's no wonder that for many years, we have looked for ways to kill bugs. While some of the bacteria we carry can cause diseases, some are “good” and useful. "Good" bacteria helps us break down the nutrients in food, educate the body's immune system to recognize enemies, fight off food poisoning, metabolize drugs and produce moods' determining chemicals. Unfortunately, some of our activities can significantly reduce the number of healthy bacteria. To replenish the lost bacteria, you can take harmless live bacteria and yeasts commonly called probiotics. Probiotics occur naturally in our bodies, but you can also get them in certain foods and supplements.
How Probiotics Work Probiotics are essential in food digestion and absorption process. They help move food through the gut. It's for this reason that probiotics can help manage conditions such as irritable bowel syndrome, infectious diarrhea, and antibiotic-related diarrhea. The absorption of adequate nutrients leads to a stronger immune system. Good bacteria are essential for gut health. Modern medicine has found a great link between gut health and the body's immune system. Unfortunately, necessary antibiotics kill bacteria indiscriminately. Probiotics can boost our disease fighting capabilities by replacing lost helpful bacteria. Probiotics can also boost the body's immunity by offering us protection from “Bad” bacteria. They protect us by lowering the number of disease-causing bacteria in the system. Probiotics also help balance "good" and "bad" bacteria. Balance is essential for optimal body performance. Numerous medical studies have for instance shown that cesarean babies are more prone to allergies and eczema because they have lower levels of helpful bacteria and chemical imbalances in their immune systems. Beneficial bacteria are not created equal. Our personal gut bacteria depends on the food and supplements we take. Research has shown that some species can produce immune-boosting chemicals. Some bacteria, for instance, can produce chemicals that are great for heart and gut lining health. References //www.mayoclinic.org/healthy-lifestyle/consumer-health/expert-answers/probiotics/faq-20058065
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3202) Can Niacin Really Lower Cholesterol?
Date:
January 09, 2014 05:14 PM
What is Niacin Niacin, commonly known as vitamin B3, was associated with lower LDL cholesterol levels several times, and many studies have proven that taking this organic compound correctly can successfully help one boost his HDL, or “good,” cholesterol levels while lowering LDL cholesterol and triglycerides as well. Niacin has the capacity to improve all lipoproteins in the organism when it is taken in doses above daily recommended intake. Benefits of Niacin Moreover, once niacin is consumed in proper dose, the LDL cholesterol will decrease by 10 to 20 percent, while the triglycerides will be reduced by 20 to 50 percent, increasing HDL cholesterol from 15 to 35 percent. There are two types of niacin: immediate release and timed release, which may influence its potentially beneficial effects and potency. Specialists recommend consuming immediate-release niacin when starting to include this vitamin within your diet, as this will theoretically ensure you of faster results. Discussing with your healthcare provider regarding the most suited type of niacin per your requirements will help you make a step forward towards healthy cholesterol levels and, consequently, better cardiovascular health. However, niacin has the capacity to send the LDLs produced by the body back to the liver as well, where their synthesis will be inhibited in order to prevent increasing “Bad” cholesterol levels. Incorporating foods that are rich in niacin to your diet will allow you to increase your HDL cholesterol levels and lower LDL ones, leading to a healthier heart. However, consulting a specialist before taking niacin is mandatory, as there have been a number of side effects associated with taking this product, including flushing and high blood pressure. In addition, niacin supplements might constitute an efficient way to lower your “Bad” cholesterol levels safely if you are unable to consume foods that contain this vitamin. In the end, lowering your bad cholesterol levels and triglycerides will make you feel significantly better and will prevent numerous cardiovascular diseases from occurring.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2957) What Are The Health Benefits Of Solaray Avena Sativa?
Date:
December 28, 2012 12:52 PM
Avena Sativa is a botanical that is used for food and as medicine. Commonly known as groats or oats, the plant is available as tea or as a liquid extract. Over the years, Avena Sativa has been used as medicine for improving the functions of certain body organs. This plant is beneficial in so many ways. Let us look at some of its benefits. Calms the Nerves Avena serves as a remedy for anxiety, stress and depression. It helps to calm the nerves and may be taken by an individual who finds it difficult to concentrate. It can also be used to relieve insomnia associated with stress and nervous irritation. Improves heart health Medical experts have revealed that Avena Sativa can help to lower the “Bad” low density lipoprotein and cholesterol level. It contains ingredients such as beta glucan, a soluble fiber which is very beneficial to the body. Further more, Avena sativa helps to treat palpitation and various heart problems. Such benefits help to strengthen the heart and make it healthy at all times. Fights Inflammation Avena Sativa helps to fight inflammation, thanks to a molecule called avenanthramides. This molecule helps to reduce the levels of inflammatory cytokines. When the levels of cytokines are high they raise the risk of chronic illnesses like heart diseases and diabetes. Natural Sex Booster Dr. Ray Sahelian, the author of “natural sex boosters, identified avena sativa as a mild sex enhancer. Hence, its impact on the libido cannot be pushed aside. As you can see, Avena Sativa has lots of benefits. It can boost hormone levels and stimulate cell growth. Since it is rich in minerals, it may help an individual who is suffering with the thyroid glands. Meanwhile, you can opt for the Solaray avena sativa available at VitaNet (R), LLC
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2787) Beta Sitosterol
Date:
June 28, 2008 11:46 AM
Phytosterols are the group of naturally occurring plant compounds which have two significant health benefits. First of all, phytosterols reduce blood levels of total cholesterol and the “Bad” LDL cholesterol. Second, which is particularly good for men, phytosterols can reduce symptoms of benign enlarged prostate. These naturally occurring plant compounds are added to many common cholesterol-reducing foods, but can also be taken as capsules. Even though the word phytosterol may sound a little like steroid, phytosterols do not have any hormonal activity. Phytosterols are known by a large variety of names such as plant sterols, free sterols, and sterol esters. A related group of compounds, which are called stanols, are gathered from trees, not from plants. Phytosterols chemically consist of beta-sitosterol, campesterol, and stigmasterol. The structure of phytosterols is similar to that of cholesterol, but is poorly absorbed. Because of these traits, phytosterols function as cholesterol blockers by reducing the absorption of cholesterol from food and re-absorption of cholesterol from the intestine, which ultimately leads to lower levels of blood fats. Actually, the U.S. Food and Drug Administration now allows companies to claim that phytosterols-containing products are able to lower the risk of heart disease. Phytosterols can also be found in a large variety of plant foods, which includes fruits, vegetables, herbs, nuts, grains, and cooking oils. Additionally, saw palmetto, which is an herb that is commonly used to treat benign prostate enlargement, is rich in phytosterols, especially beta-sitosterol. Many studies have been done that show the abilities of phytosterols supplements to reduce cholesterol levels significantly. One study conducted at East Tennessee State University, researched both sterol esters and placebos on the same group of sixteen people. The results showed a five percent decrease in total cholesterol and four percent decrease in LDL cholesterol after taking a modest dose of sterol esters for four weeks. Additionally, triglyceride levels decreased by nine percent while HDL cholesterol increased by four percent. Another study in which 2.6 grams of phytosterols were taken daily for 12 weeks resulted in a decrease of 3.5 percent in total cholesterol and 5 percent in LDL cholesterol. Due to this, it is suggested that those wishing to supplement in order to improve cholesterol levels should take 1.3 to 3 grams of sterol esters daily. Several other studies have found that supplements of beta-sitosterol can significantly reduce urinary symptoms of benign prostatic hyperplasia, which commonly affects men ages 50 and older. The benefits can be long term to those men who continue taking supplements of about 200 mg of beta-sitosterol three times daily.
For those people with moderately elevated cholesterol, phytosterols can be an ideal natural alternative to drugs. Even those people who are already taking cholesterol-lowering drugs can benefit by phytosterols ability to further enhance the benefits of medications. In order to lower cholesterol, it also helps to reduce the intake of hydrogenated vegetable oils and refined sugars and starches, along with increasing physical activity. Dosages between 1.3 and 3 grams daily are likely to reduce cholesterol and LDL-cholesterol levels. The higher dosage is linked to greater reductions in cholesterol. Take phytosterols capsules along with food, for best results.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1828) Join The Age Specific Probiotic Revolution For Better Health
Date:
January 18, 2008 10:54 AM
Probiotics are good or friendly bacteria that may just be the most important supplement of all. Probiotics may help boost your immunity, heal disease, and according to recent research, help prevents cancer. All of the above especially applies to both babies and vulnerable older adults. Along with helping people to maintain healthy populations of beneficial bacteria, probiotics have many other health benefits. One that has recently become known is the ability to protect against colon cancer. A recent study in Ireland found that probiotics, which are live bacteria that can benefit health, may also be just as important as vegetables, legumes, whole grains, and regular exercise in our strategies to lower the risk of cancer. This study was performed on eighty patients who had had either colon cancer tumors or polyps recently removed. Each patient received either a probiotic or a placebo. Included in the probiotic was Lactobacillus rhamnosus and a Bifidobacteria that was combined with other probiotics. These formulas which contain live probiotics and prebiotics are known as synbiotics. After three months of use, the balance of colon bacteria in those receiving the symbiotic formula had changed to having more lactobacilli and Bifidobacteria and less of the bacteria that is linked with increasing cancer risk, as compared to those patients who received placebos. Additionally, those patients who received synbiotics showed a decrease in DNA damage in the lining of the colon along with a decreased growth and reproduction of colon cells. Also, neither of the groups reported any adverse effects of the synbiotics. These findings were also consistent with those of earlier studies, concluding that “Bad” bacteria can produce substances that promote the development of colon cancer. Probiotics have also been shown to decrease abnormal colon cell development and DNA damage in animals. However, these findings are not yet enough for the FDA to allow the claims that probiotics work against colon cancer, but rather simply state that they support colon health. These studies certainly suggest that the right beneficial strains in the right amounts of probiotics in your gut are a great amount better for you than too much of the bad bacteria. Many people take a lifetime approach to probiotics, believing that they are appropriate for people of all ages, from babies to children to adults. Probiotics have an immunomodulatory effect at any age by stimulating and boosting the immune system. Even for infants, probiotics are critical. It has been shown that mothers who take a probiotic blend during pregnancy have babies who are less prone to eczema and other allergic conditions. Additionally, the advent of new methods has made it possible to characterize the gut microbiota changes as we age, and in health and disease. Because of this, products that target specific issues and ages have been produced which can work with each individual’s needs. The two key bacteria helping advanced adults are Lactobacillus rhamnosus and Bifidobacteria, as they provide the additional bacterial strains that are associated with the older adult’s needs. Additionally, newborns and babies do not need the same composition as adults. Instead, products for babies include B. infantis, B. bifidum, and B. breve. The greatest thing about probiotics is that you can’t overdose. Probiotics are always quite safe and very effective. When buying a probiotic supplement, look to your local health food store to find the freshest name brand probiotic because not all probiotics are made the same.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1693) Reduce Your Cholesterol With Natural Vitamins
Date:
July 12, 2007 08:58 AM
Thanks to the excellent efforts of health education organizations like the American Heart Association, we’ve learned a lot about cholesterol and how it affects our health.
We know: high cholesterol levels increase our risk for heart attacks and strokes: lowering our cholesterol levels will reduce this risk and keep our hearts and blood vessels healthy; and that diet, weight loss, and exercise will all help us in our quest to lower our cholesterol levels. We also know at times, despite these good efforts, some people’s cholesterol levels are still too high.
Prescription drugs to lower cholesterol are now available and they are heavily advertised by the pharmaceutical companies that make them. What the commercials neglect to say is these medications, collectively called statin drugs, have some serious side effects. Statin drugs can cause elevations in liver enzymes, an indication of liver irritation. They are associated with myopathy, a painful disorder of muscle inflammation and muscle degeneration. Ironically, statin drugs significantly reduce CoQ10 levels in the body, a deficit that can lead to heart disease.
Statin drugs have also been linked to a rare and at times, fatal condition called rhabdomyolysis. Because of this alarming link, the makers of cerivistatin, a popular stain drug, recalled this medication from the market on August 8, 2001. The Food and Drug Administration a greed with the recall and supported the decision.
Thankfully, there is a safe solution to the dangers of high cholesterol levels. A natural dietary supplement is now available that can lower cholesterol very effectively without any harmful side effects. Backed by many years of scientific research and clinical study, pantethine and plant sterols, also known as phytosterols, are nature’s answer to dangerous prescription cholesterol lowering medications.
To understand how pantethine and plant sterols work to lower cholesterol levels, we need to first review what we know about cholesterol and heart disease.
Q. What exactly is cholesterol?
A. Cholesterol is a soft, waxy, fat-like substance found in every cell of the body. We need cholesterol to help digest fats, strengthen cell membranes, insulate nerves, and make hormones. Cholesterol is made primarily in the liver but also by cells lining the small intestine and by individual cells in the body. While our body makes all of the cholesterol we actually need (about 1,000 milligrams a day), we also get additional cholesterol from foods we eat.
The highest source of cholesterol are egg yolks and organ meats such a liver and kidney. No plant-derived food contains cholesterol, not even peanut butter or avocado, even though these foods are high in fat. However, all foods from animal sources such as meats, poultry, fish, eggs, and dairy products contain cholesterol.
Q. How does cholesterol cause heart disease?
A. Although cholesterol serves many important functions in the body, too much cholesterol in the bloodstream can be dangerous. When blood cholesterol reaches high levels, it builds up on artery walls, increasing the risk of blood clots, heart attack, and stroke.
The heart is a muscle, and like all muscles, needs a constant supply of oxygen and nutrients. The bloodstream transports these nutrients to the heart through the coronary arteries. If the coronary arteries became narrowed or clogged by cholesterol and fat deposits (artherosclerosis) and cannot supply enough blood to the heart, the result is coronary heart disease (CHD). IF not enough oxygen-carrying blood reaches the heart muscle, a sharp, sudden chest pain (angina) may occur. If the blood supply to a portion of the heart is completely cut off by total blockage of a coronary artery, the result is a heart attack. This is most often caused from a blood clot forming on top of an already narrowed artery.
Q. What is LDL and HDL cholesterol?
A. Cholesterol and other fats can’t dissolve in the blood and, therefore, can’t travel on their own. They have to be transported to and from the cells by special carriers called lipoproteins. The two major lipoproteins are low density lipoproteins (LDL) and high density lipoproteins (HDL). LDL is most often referred to as the “Bad” cholesterol whereas HDL is known as the “good” cholesterol.
LDLs carry cholesterol throughout the body to the cells. LDLs cause artherosclerosis by clogging up our arteries with the continual buildup of fat. HDL, on the other hand, prevents this fat buildup within arterial walls, by carrying it away from the arteries, to the liver where it is eventually processed and eliminated.
Q. What are triglycerides?
A. Triglycerides are fats used as fuel by the body and as an energy source for metabolism. Triglyceride levels fluctuate easily, changing after every meal. Increased levels are almost always a sign of too much carbohydrate and sugar intake. Triglycerides in high amounts make the blood more sluggish and less capable of transporting oxygen, particularly through the small blood vessels. High triglycerides, along with high LDL “Bad” cholesterol, are considered strong and independent risk factors for cardiovascular disease, leading to a heart attack or stroke.
There are several medications physicians can prescribe for people with elevated triglyceride levels. Some of the most effective (as well as the most harmful) are the statins. The powerful, all-natural combination of pantethine and plant sterols can safely and, just as effectively, lower both triglycerides and LDL “Bad” cholesterol and increase HDL “good” cholesterol.
Q. What is pantethine and how does it lower cholesterol?
A. Pantethine, a form of pantothenic acid (also known as vitamin B5) is found in foods such as liver, salmon, and yeast. Pantethine lowers cholesterol by blocking its production.
Cholesterol synthesis, or the production of cholesterol in the human body, is an incredibly complex process. It involves many biochemical reactions and enzymes activity requiring several steps.
Studies have shown that pantethine inhibits several of these enzymes and coenzymes. It blocks the activity of one coenzyme involved in cholesterol synthesis, HMG-CoA, by about 50%. This results in significantly lower cholesterol production. But, that’s not all. To compensate for the lowered cholesterol production, the liver pulls LDL out of the bloodstream. The end results? Studies have shown that on average, pantethine can lower total cholesterol levels by 16%, LDL cholesterol levels by 14%, serum triglycerides by 38%, and can raise HDL cholesterol by 10%.
Q. What are plant sterols and how do they lower cholesterol levels?
A. Plant sterols are the fats of plants. They are found in nuts, vegetable oils, corn, and rice. Plant sterols are structurally similar to cholesterol and are able to act as a stand-in for cholesterol and block its absorption.
The liver receives about 800 mg of cholesterol every day from intestinal absorption. Cholesterol is absorbed from the intestines through receptor sites – special channels that are shaped exactly like cholesterol molecules. The cholesterol enters these channels and is then absorbed into the bloodstream. Because plant sterols look like cholesterol, they fit perfectly into these channels. The cholesterol, being blocked from absorption, remains in our intestines where it is eventually excreted.
If we eat enough plant sterols, the amount of cholesterol transported from the intestinal tract to the liver is greatly reduced. And, just like pantethine’s effect on the liver, this cholesterol reduction causes the liver to pull LDL cholesterol out of the blood, reducing both total and LDL cholesterol levels.
Q. Can’t we get the benefit of plant sterols and pantethine just by eating those foods that contain them?
A. These amounts of plant sterol and pantethine found in food just aren’t enough to have much of an effect on our health. In order to lower cholesterol levels, we need to take a concentrated combination of pantethine and plant sterols in just the right ratio.
Plant sterols are bound in fibers in the plants. Even if we ate lots of raw fruits and vegetables, we wouldn’t be getting many of these beneficial plant fats. There are also several forms of plant sterols. Some ratios of these plant sterols are more beneficial than others. On the average, we eat 160 to 360 mg of plant sterols a day.
While pantethine is found in several food sources, it is difficult to get beneficial amounts from our food. There are about 12 mg of pantethine in 3 ounces of brewer’s yeast and 8 mg in an average serving of liver.
Q. How much pantethine and plant sterol combination should I take?
A. Many studies have examined the effects of pantethine and plant sterols on cholesterol levels resulting in the determination of the most effective amounts to take of these heart healthy nutrients.
Manufacturers of high quality nutritional supplements offer pantethine combined with plant sterols in the most beneficial ratio as determined by the research. The best results are obtained by taking a combination of 400 mg of plant sterols and 200 mg of pantethine three times a day.
Q. Should only people with actual heart disease or those with high cholesterol levels be concerned about cholesterol?
A. No, recent studies have shown that cholesterol lowering in people without heart disease greatly reduces their risk for ever developing CHD, including heart attacks and artherosclerosis. This is true for those with high cholesterol levels and for those with average cholesterol levels.
Most physicians would never consider prescribing statin drugs to people without actual heart disease or high cholesterol levels because of the many health risks of the drugs. But the combination of pantethine and plant sterols can naturally and very effectively help those people with heart disease, high cholesterol levels, high triglyceride levels (or all three!) as well as those of us just wanting added “health insurance” for our hearts.
Q. Are pantethine and plant sterols safe?
A. Yes, both pantethine and plant sterols are very safe. Some people may experience some mild stomach upset when they first take pantethine. Taking the combination of pantethine and plant sterols with meals generally solves this problem.
Conclusion
Americans have listened, learned, and most importantly, taken to heart the vast and vital information on the need to keep our cholesterol levels under control. The result? More and more Americans are lucky enough to die of old age. The Centers for Disease Control recently released a report stating that the average American life expectancy has reached a new high of 76.9 years, thanks in no small measure to fewer people who are dying from heart disease,
The authors of this report stated that we could push our life expectancy even higher. We can attain healthy, old age by eating right, exercising regularly, and taking other simple steps to promote good health and prevent serious illness and heart disease. Taking the all-natural combination of pantethine and plant sterols is one simple, yet powerful step, to keep our hearts and blood vessels healthy for a long, long time.
-- Vitamins
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1585) Selecting the Right Probiotic is the Key to proper digestion
Date:
May 05, 2007 01:16 PM
Selecting the Right Probiotic is the Key
Do you ever think about what goes into your body each day? You should. One of the key to feeling good and being healthy s eating nutritious food and making sure our gastrointestinal (GI) tract has the tools it needs to optimally digest and absorb nutrients. The GI tract includes the stomach and intestines, which work to digest foods and eliminate waste.
A variety of “good” intestinal bacteria helps to keep the digestive system running. These “good” bacteria are called probiotic bacteria, or probiotics. Probiotics digest food, process waste, and keep the “Bad” bacteria – which have the potential to cause disease and illness – in check.
This issue of Ask the Doctor will look at the probiotic bacteria that play an important role in maintaining our health and wellness: we need them, what they can do for us, and how to make sure we are getting enough. Also, we will talk about an exciting process that truly delivers probiotic bacteria taken in nutritional supplements. Encapsulated in a pearl-like sphere, they survive transport to the intestines, set up house, and exert their beneficial effects. As we will see, probiotic supplementation can help prevent and treat many different illnesses, unless the beneficial bacteria reach the intestines alive and active, the supplement is worthless.
Q. I thought bacteria were bad. How can bacteria be good for us?
A. Some kinds of bacteria do cause illnesses and disease in humans. “Strep” throat is an example of an illness caused by bacteria.
However, the majority of bacteria do not cause disease. In fact, there are types of bacteria that are actually beneficial. “Good” bacteria, known as probiotic bacteria, are used in the manufacturing of food and beverages. Some examples of foods that have probiotic food ingredients are buttermilk, yogurt, cheese, sausage, and acidophilus milk.
These same kinds of probiotic bacteria are present in our intestines and help to keep the digestive system running by digesting food and processing waste.
Q. What are probiotics?
A. Probiotics are live bacteria that are non-toxic and do not cause disease (non-pathogenic).
Some of the best-understood probiotic bacteria include members of the Lactobacillus and Bifidobacterium groups. Because of the Lactobacillus and Bifidobacterium’s ability to break down lactose, these probiotic bacteria are also known as lactic acid bacteria. Both of these types of probiotic bacteria are well studied and are available in both food and dietary supplements.
Q. Is there a difference between the probiotic bacteria that is found in yogurt, and in nutritional supplements?
A. Actually, the bacteria that are in yogurt, our intestine, and most natural supplements are the same types of probiotic bacteria, Lactobacillus acidophilus and Bifidobacteria longum. Because of this, these bacteria are referred in a generic sense as probiotics. So, the term probiotics may refer to the “good” bacteria that are present in food or that live in our intestine, or that are part of a natural supplement.
Q. Where do these probiotic bacteria come from?
A. As recently as the middle of the last century, bacteria found naturally in food ingredients were used to make a fermented food product. For example, the example, the lactic acid bacteria found naturally in milk were used to make cheese. This was known as wild fermentation.
Wild fermentations are no longer used. Today, the probiotic bacteria used in food and natural supplements are harvested via a highly controlled fermentation process. This process results in high numbers of bacteria and ensures quality and purity of the bacteria.
Q. Why are probiotic bacteria important for digestive health?
A. Normal microflora (the term commonly used for intestinal bacteria) is associated with good health. An imbalance in this natural microflora (when the beneficial probiotics are outnumbered by the harmful bacteria) is frequently associated with various disease states such as yeast infections and colon cancer.
Eating foods or taking a nutritional supplement containing probiotic bacteria can help support and modify the composition of the large intestine microflora. Microflora of the large intestine assist digestion through fermentation (by making the intestines more inhospitable to invading bacteria species), protection against disease-causing bacteria, and stimulation of the immune system.
The probiotics, Lactobacillus and Bifidobacteria, occupy a central role in the intestinal and provide health benefits.
Q. How do probiotic bacteria help with digestion?
A. Lactose is an important sugar that is converted to lactic acid by lactic acid bacteria. Lactose intolerance results from an inability to digest lactose, due to the failure of small intestine mucosal cells to produce lactase, an enzyme needed to digest lactose. This often results because of genetics, gastrointestinal disease, or because of the decline in the amount of intestinal lactase levels associated with aging. Lactase deficient people accumulate non-absorbed lactose in the gastrointestinal tract, which draws water and electrolytes into the gut and speeds waste through the intestines, leading to bloating, cramping, and diarrhea.
Approximately 50 million people in the
Lactic acid bacteria have been shown to help the breakdown of lactose, specifically by enhancing the activity of lactase (beta galactosidase), which improves lactose digestion and tolerance. Furthermore, in a randomized, controlled clinical trial, Bifidobacteria longum was shown to assist in the breakdown of lactose and relieve the symptoms of lactose intolerance (flatulence) in people with lactose intolerance.
Q. What is the difference between digestive enzymes and probiotics? Can they be taken together?
A. Digestive enzymes, such as protease, amalyse, and lipase, act upon food, breaking it down into simpler components that can be used by the body for energy. Without enzymes, digestion could not take place. Therefore, the food that we eat could not be absorbed and utilized by our bodies.
Probiotics help the enzymes to digest food and process waste. In essence, probiotic bacteria and enzymes work together to ensure that the digestive tract is running smoothly. When taken together, enzymes assure greater levels of digestion absorption of your food, and probiotic bacteria aid the enzymes in digestion and keep problems in check.
Q. Is helping to ensure a healthy digestive system the only use for probiotics?
A. Absolutely not! Probiotic bacteria, such as Lactobacillus acidophilus, have been found to help prevent vaginal yeast infections in women that suffer from these reoccurring infections.
Approximately 35% of vaginal infections are caused by the yeast. Candida albicans, Candida, is a fungus that is a component of the normal gastrointestinal microflora. However, Candida must not be allowed to increase in numbers. An overgrowth is associated with adverse health effects like vaginal infections, oral thrush, or even serious systematic yeast infections. Probiotics have been shown to keep levels of Candida in check.
Probiotic bacteria have also been demonstrated to have anti-cancer properties. In baa clinical study, colon cancer patients given Lactobacillus acidophilus fermented milk showed a significant increase in numbers of intestinal Lactobacilli and a decrease in risk factors associated with colon cancer.
Patients suffering from inflammatory bowel diseases, such as ulcerative colitis and Crohn’s disease can benefit from probiotic bacteria supplementation. Studies have shown that probiotic bacteria assist in maintaining remission in ulcerative colitis and preventing reoccurrence of Crohn’s disease. Manipulating the intestinal flora may prove to be more effective and better tolerated than the drugs that are conventionally given to treat these diseases. I one study, Lactobacillus acidophilus was found to improve the intestinal barrier and clinical status in children suffering from Crohn’s disease.
Probiotics supplementation can also improve and prevent skin disease, such as eczema. Studies have shown that probiotic bacteria can actually control inflammation associated with skin conditions. In one study, infants with eczema who were given probiotic-supplemented formulas showed a significant improvement in skin condition.
The chart below summarizes some of the diseases and conditions that probiotic bacteria can help prevent and/or improve.
Q. How often should probiotics be taken to ensure optimal support of the digestion system?
A. Probiotic bacteria do not permanently colonize in the body. They need to be replenished by the consumption of foods containing probiotic bacteria or by taking a probiotic natural supplement. Whatever form you choose to replenish the intestinal probiotics, they need to be ingested daily for their health-promoting effects to continue.
Q. If I take a probiotic nutritional supplement, how many bacteria should a good quality supplement contain?
A. The critical factor is not how many bacteria that a supplement contains, but rather how many bacteria reach the intestines healthy, vigorous, and ready to work.
A good quality supplement will deliver at least 3 billion living, healthy probiotic bacteria per dose to your intestines. The bacteria in the probiotic natural supplement should be a mixture of both Lactobacillus and Bifidobacteria.
Again, the critical key to a good quality probiotic supplement is that the bacteria must be alive to work. Only living probiotic bacteria can colonize in the intestines. A good quality probiotic nutritional supplement will have GUARANTEED levels of live bacteria at the point of consumption. Inferior brands will merely state levels of live bacteria at the point of manufacture.
Recently, a private laboratory tested various probiotic nutritional supplements in the marketplace, including one utilizing a new process that encapsulates the bacteria in a spherical, pearl-like coating. Each of these supplements were best-selling brands, two of them were enteric coated, and all had label guarantees about potency. The lab counted the levels claimed by each manufacturer.
Q. Then how do I know I am getting what I pay for?
A. First, look for a product that has a “use by” date or an “expiration” date clearly stated on the package.
It is also important to look for a probiotic supplement that does not require refrigeration. Probiotic supplements that require refrigeration often have been subjected to warm temperatures during shipment and storage that will inevitably kill off some or all of the bacteria.
It is also important that the product label guarantees live bacteria at the time of purchase, not at the time of shipment or manufacturing. However, from the laboratory test discussed, we see that sometimes these written guarantees are not worth the paper they are written on. There is one scientifically validated process that truly delivers live and vigorous bacteria to the intestine. This process suspends the probiotic bacteria in a moist paste and immediately seals the bacteria in a perfectly seamless, spherical, gelatin ball. This bacterial paste is completely protected from air and dryness so the bacteria are alive until the specialized gelatin dissolves – in the intestines.
Q. Why is it important to dissolve only in the intestine?
A. Lactic acid bacteria are not very resistant to the acids of the stomach. The harsh environment of the stomach destroys the majority of these bacteria.
This pearly-like coating technology protects bacteria from the stomach acid. The sphere is specially developed to only dissolve in the intestines. Enteric coating is not enough as it does nothing to protect the bacteria while they wait for purchase on the shelf.
Q. What does this proprietary coating technology mean to me?
A. This specialized process is an expensive processing step, but it has many advantages to you.
The pearl-shaped spheres actually “seal” the bacteria in the capsule, which protects them from air. Probiotic bacteria are anaerobic, meaning they do not require oxygen to live. In fact, the presence of oxygen can actually injure or kill probiotic bacteria. In addition, the special coating’s ability to seal the bacteria in the capsule stimulates the need for the nutritional supplement to be refrigerated – though they can be kept in the refrigerator, if desired.
By protecting the bacteria on the shelf and in the stomach, the probiotic bacteria successfully reach the intestine. As a result, there will be a greater number of healthy, intact bacteria that can colonize in the intestine.
Conclusion
Many health care practitioners believe all health issues are related in some way to the process of digestion. Probiotics play a crucial role in improving our digestive health, which, in turn, is interconnected to every single function in our bodies.
Taking a probiotic supplement is an excellent way to replenish the good bacteria in your intestinal microflora. A quality probiotic product contains two different types of bacteria from Lactobacillus and Bifidobacteria species with at least one billion live bacteria per dose.
But how do you know the bacteria re still alive? Look at the package. If there is no fate stamp, put it down. If it says the company guarantees there was a certain number alive at the time of manufacture, put it down. Tat means that the company is not willing to claim the bacteria are alive when delivered to the target site, the intestine. If the product must be constantly refrigerated, put it down. How do you know it didn’t sit in a truck for two days, or was in a warehouse before it was shipped to the health food store?
Find a probiotic that says the bacteria are guaranteed to be alive in the numbers stated on the label until the printed on the package. Find a product using unique, cutting edge science to deliver the probiotic bacteria in a form that uses spherical, sealed, triple coating to protect the bacteria. That company has gone to extra time and expense to make sure you reap the benefits that probiotics can offer.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1531) Lower Cholesterol Naturally!
Date:
October 06, 2006 09:41 AM
Because of organizations like the American Heart Association (AHA), we’ve learned a lot about cholesterol and how it affects our health. Thanks to these educational organizations, we know that high cholesterol levels can increase our risk for heart attacks and strokes and, by lowering these levels, we reduce these risks as well as keep our hearts and blood vessels healthy. We also know that our cholesterol levels can be improved through exercise, diet, and weight loss. Although we’ve learned a lot through these educational organizations, there are still a few misconceptions about cholesterol. One of these being that not all cholesterol is harmful. There are both “good” and “Bad” forms of cholesterol and a good balance between the two is what is needed for a healthy heart. Because so much emphasis is placed on lowering “Bad” cholesterol levels, not enough attention is paid to the benefit of raising “good” cholesterol levels (HDL). Research states that raising HDL levels can provide even greater protection against cardiovascular disease than just simply lowering “Bad” cholesterol levels. By raising HDL levels by simply 1%, the risk of heart disease can be lowered by 2% in men and 3% in women. Many studies have shown that low HDL cholesterol levels are an independent risk factor in heart disease. This is extremely important because we’ve learned that despite efforts to change a person’s diet and exercise habits, some people’s cholesterol levels are still unhealthy. Prescription drugs to lower cholesterol are now available and have been proven by multiple studies to be very successful. The statins’ effectiveness in reducing LDL (“Bad”) cholesterol has produced highly significant reductions in heart attacks and strokes. Although these medications do lower cholesterol levels, their side effects must be considered. Statin drugs can cause liver irritation, reduce CoQ10 levels in the body, are associated with myopathy, and are even linked to a rare and sometimes fatal condition called rhabdomyolysis. These drugs also have a relatively small effect on good (HDL) cholesterol levels. Thankfully, there are safe and effective solutions available that can help you manage your cholesterol levels naturally. However, first we must review what we know about cholesterol and heart disease. Cholesterol is a fat-like substance needed to help digest fats, strengthen cell membranes, make hormones and insulate nerves. Although it is found in every cell of the body, cholesterol is mainly made in the liver, as well as cells lining the small intestine. Even though our bodies make all the cholesterol we need, we also get cholesterol from the foods we eat, such as egg yolks and organ meats. All foods from animal sources contain cholesterol, while plant derived food, including peanut butter and avocado, contains no cholesterol at all. Cholesterol is important to many functions of the body. However, too much cholesterol in the bloodstream is extremely dangerous. After blood cholesterol reaches high levels, it builds up on the artery walls, and thus increasing the risk for blood clots, heart attack, and stroke. If the cholesterol clogs any of the coronary arteries, the heart’s supply of oxygen and nutrients will diminish, resulting in coronary heart disease, angina, or even heart attack. Because cholesterol and other fats can’t dissolve in the blood and thereby can’t travel on their own, they have to be transported to and from the cells by lipoproteins. The two major lipoproteins are low density lipoproteins (LDL or “bad cholesterol) and high density lipoproteins (HDL or “good cholesterol”) LDLs carry cholesterol throughout the body to the cells and cause artherosclerosis by clogging up our arteries with fat. On the other hand, HDL prevents the fat buildup by carrying it away from the arteries and to the liver where it can be eliminated. Although high levels of LDL are associated with cardiovascular disease, high HDL can drastically reduce your risk of heart disease. As a result, the AHA has established three guidelines to keep your heart healthy: HDL levels about 40 for men and above 50 for women, LDL levels between 100 and 159, and a total cholesterol (HDL and LDL) of under 200. Triglycerides are fats used as fuel by the body and a source for metabolism. These levels can fluctuate easily but increased levels are almost always a sign of too much carbohydrate and sugar intake. High amounts of triglycerides make the blood less capable of transporting oxygen and are another factor for cardiovascular disease. Thankfully, the HDL and LDL blend mentioned earlier can safely and effectively lower triglyceride levels. It has been shown that high levels of HDL cholesterol are inversely related to coronary artery disease risk. However, what people do not know is that there are different subtypes of HDl, including HDL-2 and HDL-3. HDL-3 is produced by the liver and intestines and is responsible for scooping up free cholesterol from the blood vessel walls. The cholesterol carried by HDL-3 is chemically modified, forming a larger-sized subtype, known as HDL-2, or “mature HDL.” HDL-2 transports cholesterol to the liver for processing and elimination, and its molecules are then recirculated in the blood stream. Research has shown that HDL-2 provides more heart-protection because it moves the cholesterol away from arterial walls, and holds a greater number of receptor sites which allows it to carry a larger amount of cholesterol to the liver. Although many prescription medications have been developed to lower bad cholesterol, there are very few medications that target good cholesterol. Therefore, patients with naturally low HDL cholesterol, who can not alter these levels through diet and exercise, have limited medical options to reduce their risk of heart disease. Multiple nutrients have been clinically shown to favorably alter good cholesterol levels including: vitamins C, E, B6, B12, niacin, folic acid, magnesium and selenium, with protein-building amino acids, powerful antioxidants such as coenzyme Q10, alpha lipoic acid, N-acetyle cysteine, and policosanol, and extracts of hawthorn, garlic, grape seed, and soy isoflavones. Although this HDL-boosting combination does not result in a significant reduction in LDL, antioxidants found in this formulation can help stabilize LDL and prevent build up in the arterial wall. This formula combines essential vitamins and minerals, at levels recommended by the American Heart Association. It contains amino acids, antioxidants, and botanicals that have all been used safely for years. No serious adverse effects have been found following supplementation and the combination is safe to use with statin drugs. Plant sterols, found in nuts, vegetable oils, corn, and rice are structurally similar to cholesterol and are able to block its absorption. Each day the liver receives about 800 mg of cholesterol from intestinal absorption through receptor sites. After entering these channels, the cholesterol is absorbed into the bloodstream. Since plant sterols look similar to cholesterol, they fit perfectly into these receptor sites and block the absorption, which allows the cholesterol to remain in our intestines where it can eventually be excreted. A large amount of plant sterols reduces the amount of cholesterol transported from the intestinal tract to the liver. This cholesterol reduction causes a decrease in LDL levels. Even if a person does not have high cholesterol levels, reducing bad and raising good cholesterol greatly reduces their risk for ever developing chronic heart disease. Due to side effects, physicians do not normally prescribe statin drugs to people without actual heart disease of high LDL cholesterol levels. Instead, they recommend dietary changes. The HDL-boosting combination and LDL-lowering pantethine and plant sterols blend can effectively help people with heart disease, uncontrolled cholesterol levels, high triglyceride levels, or people who just want to improve their heart health.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1399) In Vitro Study Shows Promise for Hibiscus Extract on Cholesterol
Date:
July 06, 2006 12:04 PM
Hibiscus (Hibiscus rosasinensis L.) contains many antioxidant compounds, such as flavonoids, polyphenols, and anthocyanins, which previous research has shown may help prevent low-density lipoprotein (LDL or “Bad”) cholesterol from oxidizing. A new study, published in the journal Food and Chemical Toxicology (2006, vol. 44: 1015-1023), focused on the effects of anthocyanin extracts from hibiscus on LDL oxidation, as well as fragmentation of apollpoprotein B (ApoB), which is responsible for the transport of cholesterol to tissues. Results showed that depending on the dose (0.25, 0.50, or 1.0 milligrams per milliliter of anthocyanins), the extract reduced LDL cholesterol_oxidation by 13, 56, and 75 percent, respectively. All three concentrations also appeared to have scavenged approximately 100 percent of free radicals.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1322) HDL Booster - Boost your good cholesterol
Date:
March 16, 2006 12:51 PM
HDL BOOSTER
(Product No. 02922)
DESCRIPTION:
HDL Booster is a physician-developed dietary supplement that has been clinically shown to increase good cholesterol levels, particularly HDL-2, the best form of cholesterol.* The formula combines essential vitamins and minerals, at levels recommended by the American Heart Association (AHA), with key amino acids, powerful antioxidants, and traditional herbal extracts to provide superior support for cardiovascular health.*
HDL Booster:
· Formulated by Dr. Dennis Goodman, Chief of Cardiology at
· Clinically studied to increase good cholesterol levels up to 23%*1
· All-inclusive formula; includes ingredients recommended in accordance with the American Heart Association
· Replaces the CoQ10 depleted by cholesterol lowering (statin) drugs.*2
STRUCTURE/FUNCTION:
HDL Booster has been clinically shown to increase HDL cholesterol levels.* HDL Booster also supports healthy cholesterol and healthy triglyceride levels already within the normal ranges.* By reducing C-reactive protein levels, HDL Booster helps support the body’s natural anti-inflammatory response.*
FORMULA:
Two tablets (one serving) contain:
Vitamin C (ascorbic acid) 148 mg
Vitamin E (as natural mixed tocopherols) 35 IU
Niacin (as niacinamide) 21 mg
Vitamin B6 (as pyridoxine HCl) 3 mg
Folic Acid 301 mcg
Vitamin B12 (as cyanocobalamin) 20 mcg
Magnesium (from magnesium amino acid chelate) 10 mg
Selenium (as L-selenomethionine) 49 mcg
Proprietary Blend 388 mg
hawthorn (Crategus oxyacantha) berry extract,
taurine, garlic (Allium sativum) bulb, grape seed (Vitis
vinifera) extract, grape skin (Vitis vinifera) extract,
N-acetyl-L-cysteine, alpha-lipoic acid, soy (Glycine
max) isoflavones, tocotrienols
L-Arginine (as L-arginine HCl) 153 mg
L-Carnitine (as L-carnitine L-tartrate) 51 mg
Coenzyme Q10 (CoQ10)(ubiquinone 10) 25 mg
Policosanol 7 mg
Other ingredients: See label for most current information.
Contains no: sugar, salt, yeast, wheat, gluten, corn, dairy products, artificial coloring, artificial flavoring, or preservatives. This product contains natural ingredients; color variations are normal.
INTRODUCTION:
Cholesterol, the soft, waxy substance present among the lipids (fats) in the bloodstream and in all cells, is important for wide variety of physiological functions. It is essential for the formation of cellular membranes, necessary for the production of bile salts, and also plays a role in the synthesis of certain hormones.3-5
Cholesterol is both produced by the body and obtained from food. Endogenous cholesterol is formed by human cells, particularly liver cells, whereas exogenous cholesterol is absorbed through the gastrointestinal tract from food.3,4
Because cholesterol can not be metabolized for energy, it must be removed from the body once it has served its function. The major route of removal is through the liver, where it is processed and subsequently excreted from the body.3,4
Types of Cholesterol
Cholesterol is lipophilic (“fat loving” or water insoluble) by nature. It can not be dissolved in the blood, and must, therefore, be transported by carriers known as lipoproteins. These carriers are classified by density, with LDL (low density lipoproteins) and HDL (high density lipoproteins) being the most common.4,5
LDL is often referred to as “Bad” cholesterol. LDLs carry cholesterol throughout the body. Conversely, HDL, or “good” cholesterol, is responsible for carrying cholesterol away from the arteries to the liver where it is eventually processed and eliminated from the body.3,4,6
Scientific studies have shown that both types of cholesterol are important indicators of cardiovascular health. But recent research, focusing on the beneficial subtypes of HDL, has found that certain fractions of HDL may be more supportive of cardiovascular health than others. The two most notably supportive HDL fractions are HDL-2 and HDL-3.7
The smaller HDL-3 is synthesized by the liver and intestines. This form, which is known as “free cholesterol-rich” HDL, scavenges or “scoops up” free cholesterol. The cholesterol is then chemically altered by the addition of an ester group. When sufficient cholesterol is esterified, HDL-3 becomes HDL-2, which is therefore referred to as “cholesterol ester-rich” HDL. HDL-2 is larger in size and has been shown to be more cardiosupportive than HDL-3.*7
HOW IT WORKS:
HDL is known to possess antioxidant activity and to help balance the body’s natural anti-inflammatory response, both of which are important for cardiovascular health, but its most important function is the role it plays in cholesterol transport.6,8 High levels of HDL cholesterol are also associated with reduced platelet activity, another key indicator of arterial and venous health.9
Both HDL and LDL levels are important indicators of healthy cardiovascular function.* Therefore, supplements that increase the level of good cholesterol can profoundly impact heart health.* In 2002, an open label pilot study was conducted at
The following chart summarizes the benefits of each of the ingredients in HDL Booster:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1238) Astaxanthin - PHYTONUTRIENT ANTIOXIDANT
Date:
December 28, 2005 10:20 AM
"PHYTONUTRIENT ANTIOXIDANT" Astaxanthin
Carotenoids are a class of lipid-soluble natural pigments found in plants, as well as in phytoplankton and certain fungi and bacteria. The red, orange and yellow colors seen in fruits and vegetables are from carotenoids. When various aquatic animals such as salmon and shrimp eat plants containing some of the over 700 compounds that make up the carotenoid class, those animals are also decorated with the same brilliant colors. However, carotenoids do more than provide color - they’re powerful phytonutrient antioxidants. Beta carotene, lutein, and lycopene are some of the more well-known carotenoids, but the most powerful found to date is astaxanthin. Astaxanthin is a fat-soluble carotenoid with a unique molecular structure that makes it an extremely effective antioxidant. The PDR® Medical Dictionary 2nd Edition defines an antioxidant as, “An agent that inhibits oxidation; any of numerous chemical substances, including certain natural body products and nutrients, that can neutralize the oxidant effect of free radicals and other substances.” Not only is astaxanthin a potent free radical scavenger, but it also can protect against oxidation, which limits the number of free radicals produced. Additionally, it’s very effective at quenching a molecule called singlet oxygen, a harmful reactive oxygen species formed through normal biological processes. Singlet oxygen possesses a high amount of excess energy that must be released to keep it from damaging other cells. Astaxanthin absorbs this energy and dissipates it as heat, and in the process returns the singlet oxygen to a grounded state. A growing body of research is showing that astaxanthin is the creme de la creme of phytonutrient antioxidants. Studies comparing astaxanthin to other carotenoids have shown it to possess antioxidant activity up to 10 times stronger than that of beta carotene, canthaxanthin, lutein and zeaxanthin.4 A study published in 1990 conducted by Kurashige and associates compared the effectiveness of vitamin E and astaxanthin for the prevention of lipid peroxidation. The results showed that astaxanthin is 100-500 times more effective in preventing lipid peroxidation in vivo than vitamin E.5 Astaxanthin in algae provides protection against the effects of ultraviolet (UV) light exposure, and studies are showing that this protective effect is also imparted with dietary astaxanthin. Scientists believe that astaxanthin effectively scavenges the oxygen radicals produced through photo-oxidation caused by UV exposure. A 1995 study by Savoure and associates studied the protective effects of astaxanthin, beta carotene and retinol against UVinduced photo-oxidative stress. The results showed that astaxanthin is extremely effective in preventing increases of certain polyamines created through photo-oxidation, which damages skin. A particular polyamine was found to increase only 1.5-fold in subjects fed astaxanthin, whereas subjects in the control group experienced a significant 4.1- fold increase. It was concluded that astaxanthin works through a particular enzyme, increasing this enzyme’s consumption of polyamines in response to irradiation. Research has shown that astaxanthin also offers cardioprotective effects through its ability to decrease oxidation of HDL (“good” cholesterol), which is a cholesterol transporter in the blood. It‘s well established that high levels of HDL and low levels of LDL (“Bad” cholesterol) are desirable for healthy cardiovascular function, so protecting HDL from oxidation means there’s more circulating in the bloodstream. In a 1992 study by Murillo, subjects were fed dietary astaxanthin for 30 days. HDL cholesterol increased 57mg/dL, compared to the control diet (42.4 mg/dL). LDL cholesterol decreased from 12.5 mg/dL to 9.6 mg/dL. Clearly, astaxanthin exhibited an influence on the ratio of these two lipoproteins. We can thank the lobster for the discovery of astaxanthin. Researchers working with an extract of the lobster Homarus astacus first characterized astaxanthin in 1938. It was soon discovered that astaxanthin is abundant in nature, although mostly in very low concentrations. The greatest source found is in green algae called Haematococcus pluvialis, which also contains other carotenoids such as beta carotene and lutein. NOW® Foods Astaxanthin supplies 4mg of this effective phytonutrient antioxidant and is an excellent source of this outstanding member of the carotenoid family. The astaxanthin used for our product is BioAstin® supplied by the Cyanotech Corporation, one of the premier suppliers of highquality astaxanthin taken from Haematococcus pluvialis, the richest natural source discovered. In addition to Astaxanthin, NOW® offers other carotenoids, including Lutein, Beta Carotene and Lycopene. Research continues to support the inclusion of carotenoids in the diet to support overall health. This is even truer for those with less than perfect diets and for those who smoke or spend any time with someone who does.
References
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1100) Using pecans in the fight against LDL cholesterol
Date:
October 18, 2005 10:45 AM
Using pecans in the fight against LDL cholesterol New research out of the Journal of the American Dietetic Association suggests that although pecans are high in fat, they may actually lower “Bad” LDL cholesterol. Dr. Wanda Morgan and fellow researchers at New Mexico State University studied the effect of adding pecans to the diet by observing the diets of individuals with normal cholesterol. Those in the pecan group ate sixty-eight grams of pecans each day, while those in the control group continued their normal diet and avoided nuts. Those in the control group experienced no change in their LDL cholesterol levels, but those who added pecans to their diets experienced an average ten percent drop in their LDL cholesterol.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=848) Sytrinol can lower Cholesterol by 27% - 34%
Date:
September 20, 2005 09:56 AM
Sytrinol – MultiPronged Heart Health According to the American Heart Association, more than 60 million Americans suffer from on of more forms of cardiovascular imbalances. When we add in those individuals with blood cholesterol concerns, we see over 100 million Americans who may be in need of specific diet and lifestyle recommendations for achieving and maintaining heart health. Aside from the generalized recommendations that we typically hear for heart health (lose weight, exercise more, and eat less fat and more fruits and vegetables) There are a number of potentially beneficial dietary supplements that may help to maintain cholesterol levels in the normal range. Among supplements there is a wide range of safety and efficacy between products—but a newer product called Sytrinol stands out for its clinical effectiveness. Sytrinol is a patented blend of polymethoxylated flavones (from citrus) and tocotrienols (from palm fruit). One of the factors that sets Sytrinol apart from existing natural products for heart health is its multipronged approach to controlling multiple factors related to overall heart health—including control of cholesterol, cellular irritation, oxidation, triglycerides, and others. Cholesterol Conundrum While it is unarguable that cholesterol is an important contributor to overall heart health, it couldn’t be further from the truth that cholesterol is the “only” or even the most important factor when it comes to protecting your heart. Did you know that approximately HALF of all serious heart challenges each year are experienced by people with NORMAL cholesterol levels? If Cholesterol is not to blame, then what is? In addition to total cholesterol levels (the “number” that you may know as 200 to 240 of other values in “mg/dl” units), we know how that LDL and HDL matter a lot (Low-density lipoprotein—the “Bad” cholesterol, and High-density lipoprotein—the “good” cholesterol). We also know that some forms of the bad and LDL can be “Badder” than others—specifically those with lots of structural protein called “apolipoprotein B” (which tends to encourage LDL cholesterol to become embedded in your blood vessel linings—bad!). In addition to our total cholesterol, LDL, HDL, and the various apoproteins, we also need to know our triglyceride levels, our levels of cellular irritation, what our free radical load looks like, and what our antioxidant defenses are. Sytrinol addresses each of these important aspects of heart and health simultaneously. The Sytrinol Solution Polymethoxylated Flavones (PMFs) in Sytrinol are just what they sound like – flavonoid compounds with extra methoxy groups compared to “regular flavones. Like all flavonoids, the PMFs deliver potent antioxidant activity, but the PMF version is about three times more potent in its ability to address cholesterol levels (20% - 30% reduction in clinical Studies). The two primary PMFs are nobiletin and tangeretin. In addition to the PMFs, Sytrinol contains palm tocotrienols—one of the most potent antioxidant nutrients known. An interesting effect of tocotrienols is a reduction in cholesterol synthesis in the liver—by a mechanism similar to (but safer than) the commonly utilized mechanism of inhibition of the HMG-CoA Reductase Enzyme. Sytrinol is known to work via several unique mechanisms to reduce triglycerides (TG), total cholesterol (TC) and low-density lipoprotein cholesterol (LDL). First, by reducing DGAT activity (Diacylglycerol acetyl transferase) and increasing liver PPAR (Peroxisome porliferator-activated receptor)—Sytrinol can reduce overall synthesis of TG (DGAT inhibition). The overall effect is to reduce TG levels in the blood by two complementary mechanisms. In terms of LDL effects, Sytrinol also reduces both Apolipoprotein B levels (ApoB—needed for the synthesis of LDL particles) and MTTP levels (microsomal triglyceride transfer protein-needed to transfer fat into the new LDL particles). By reducing levels of both these tructural LDL components, Sytrinol reduces overall LDL levels, and thus total cholesterol levels, in the blood. The clinical results behind Sytrinol are impressive—showing a reduction in levels of total, LDL, and triglycerides by 27% - 34% within 4 weeks. In one of these studies, ApoB levels were reduced (suggesting reduced LDL) and ApoA1 levels were increased (suggesting increased HDL)—as would be expected based on the biochemistry of PMFs and tocotrienols. Sytrinol is also wonderfully safe—and at the effective dose of 300mg daily, users will benefit from its multipronged effects. One aspect of Sytrinol safety that I especially like is the finding that, unlike some flavonoids like naringin from grapefruit, there are no known risks of drug interactions with the form of citrus derived PMFs found in Sytrinol (certain grapefruit flavonoids can interfere with liver enzymes needed to metabolize many prescription drugs). Summary Not since Red Yeast Rice was removed from the market by the FDA, have we had a truly effective, multimechanism solution for cholesterol control (and nearly total heart health). There are certainly other options for addressing heart health and cholesterol levels, but among the available choices, such as policosanol, guggulipid, niacin, and plant sterols, we’re looking at about half the cholesterol-lowering ability (10% - 15% in most cases) compared to Sytrinol. If youre in the “borderline” zone of cholesterol levels (about 240mg/dl and below), you should absolutely consider Sytrinol to keep your cholesterol levels under control. References Kurowska EM, manthey Ja. Hypolipidemic effects of absorption of citrus polymethoxylated flavones in hamsters with diet-included hypercholesterolemia. J Argic food chem.. 2004 may 19;52(10):2879-86. Kurowska EM, manthey Ja, Casaschi A, Theriault AG. Modulation of HepG2 cell net apolipoprotein B secretion by the citrus polymethoxyflavone, Tangeretin. Lipids 2004 feb;39(2):143-51. Manthey JA, Grohmann K, Montanari A, Ash K, Manthey CL, Polymethoxylated flavones derived from citrus suppress tumor necrosis factor-alpha expression by human moncytes. J Nat Prod. 1999 mar;62(3)441-4. Mora A, Paya M, rios JL, Alcaraz MJ. Structure-activity relationships of polymethoxyflavones and other flavonoids as inhibitors of non-enzymic lipid peroxidation. Biochem Parmacol. 1990 Aug 15;40(4):797-7. Takanaga H, Ohnishi A, Yamada S, Matsuo H, Morimoto S, Shoyama Y, Ohtani H, Sawada Y. Polymethoxylated flavones in orange juice are inhibitors of P-glycoprotein but not cytochrome P450 3A4. J Pharmacol exp. Ther. 2000 Apr;293(1):230-6. By: Shawn M. Talbott, PH.D. Disclaimer: The above article is for informational purposes only and is not intended to diagnose or treat a particular illness. The reader is encouraged to seek the advice of a holistically competent licensed professional health care provider. The information in this article has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=791) Lowering cholesterol safely
Date:
July 27, 2005 04:10 PM
Lowering cholesterol safely. By Kim Vanderlinden, N.D., D.T.C.M. Atherosclerosis and its complications are major causes of death in the United States and have reached epidemic proportions throughout all of the Western world. Heart disease accounts for 36% of all deaths among Americans and ranks as the number-one killer; stroke; another complication of atherosclerosis; is the third most common cause of death. Foremost in the prevention and treatment of heart disease is the reduction of blood cholesterol levels. The evidence overwhelmingly demonstrates that elevated cholesterol levels greatly increase the risk of death due to heart disease. The first step in reducing risk for heart disease is keeping your total blood cholesterol level below 200 mg/dl (milligrams per deciliter). Not all cholesterol is bad; it serves many functions in the body, including the manufacture of sex hormones and bile acids. Without cholesterol, many body processed would not function properly. Cholesterol is transported in the blood by molecules known as lipoproteins. Cholesterol bound to low density lipoprotein, or LDL, is often referred to as the “Bad” cholesterol, while cholesterol bound to high-density lipoprotein, or HDL, is referred to as the “good” cholesterol. LDL cholesterol increases the risk of heart disease, strokes, and high blood pressure, while HDL cholesterol actually protects against heart disease. LDL transports cholesterol to the tissues. HDL, on the other hand, transports cholesterol to the liver for metabolism and excretion from the body. Therefore, the HDL-to-LDL ratio largely determines whether cholesterol is being deposited into tissues or broken down and excreted. The risk for heart disease can be reduced dramatically by lowering LDL cholesterol while simultaneously raising HDL cholesterol levels. Research has shown that for every one percent increase in HDL levels, the risk for a heart attack drops three to four percent. Dietary cholesterol Dietary cholesterol is a major risk factor in developing atherosclerosis. The evidence is substantial. However, several studies have shown that a lower dietary cholesterol intake was associated with up to a 37% lower risk of death from any cause, or an increased life expectancy of roughly 3.4 years. Although dietary cholesterol intake is an important contributor to atherosclerosis, most of the cholesterol in the body is actually manufactured in the liver. Reducing dietary cholesterol alone is not always sufficient to lower blood cholesterol levels. Common drugs In an attempt to reduce blood cholesterol levels, many physicians are ignoring the need to give dietary recommendations and are instead utilizing drugs as the primary treatment. Using drugs before diet is clearly not the best approach, in terms of both effectiveness and cost. In fact, the Report of the National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of High Cholesterol in Adults clearly states: “Dietary therapy is the primary cholesterol-lowering treatment.” The drugs lovastatin (Mevacor), prevastin (Pravachol), and simvastatin (Zocor) are commonly used to lower blood cholesterol levels. The main side effect of these drugs is liver damage. In fact, due to the seriousness of the possible adverse effects on the liver, it is necessary to have periodic blood tests to determine if the drug is harming the liver. Other side effects include: muscle breakdown, muscle pain, nausea, diarrhea, flatus, abdominal pain, headache, and skin rash. The most important first approach to lowering a high cholesterol level is to follow a healthful diet and lifestyle. The dietary changes are simple: Eat less saturated fat and cholesterol by reducing or eliminating the amounts of animal products in the diet; increase consumption of fiber-rich plant foods (fruits, grains, and legumes); and lose weight, if necessary. Lifestyle changes include; Regular aerobic exercise; stop smoking; and reduce or eliminate consumption of coffee (both caffeinated and decaffeinated). Here are the six key recommendations of U.S. Surgeon General, American Heart Association, and the National Research Council’s Committee on Diet and Health:
Natural alternatives When there is a need for additional support to the dietary and lifestyle practices that can lower cholesterol levels, it simply makes more sense to use safer and more effective natural alternatives. When evaluating overall effectiveness, both LDL and HDL cholesterol levels must be taken into consideration. When you look at the cost, safety, and effectiveness, it is clear that natural alternatives are substantially superior to standard drug therapy. Keep in mind that the natural alternatives discussed are, just like the dugs, still best utilized in a comprehensive program that stresses a healthful diet and lifestyle. Niacin, or vitamin B3, has long been used to lower cholesterol levels. In fact, niacin is recommended by the National CholesterolEducation Program as the first “drug” to use to lower blood cholesterol levels. The safest form of niacin at present is known as inositol hexaniacinate. This form of niacin has long been used in Europe to lower cholesterol levels and also to improve blood flow. It yields slightly better results than standard niacin, but is much better tolerated, both in terms of flushing and, more importantm long term side effects. Gugulipid is the standardized extract of the mukul myrrh tree that is native to India. Several clinical studies have confirmed that gugulipid has an ability to lower both cholesterol and triglyceride levels. Typically, cholesterol levels will drop 14% to 27% in a four- to twelve-week period, while triglyceride levels will drop from 22% to 30%. The dosage of gugulipid is based on its guggulsterone content. Clinical studies have demonstrated that gugulipid extracts standardized to contain 25 mg of guggulsterone per tablet given three times per day is an effective treatment for elevated cholesterol levels, elevated triglyceride levels, or both. Garlic and onions exert numerous beneficial effects on the cardiovascular system, including lowering blood lipids and blood pressure. Numerous studies have demonstrated that both garlic and onions are effective in lowering LDL-cholesterol and triglycerides while simultaneously raising HDL-cholesterol levels. Final Comments Without question, the best approach to lowering cholesterol levels is through diet and lifestyle modifications. When additional support is require, there are safer and more effective natural alternatives to commonly prescribed drugs. The goal of therapy, whether natural or synthetic, is to get blood lipid levels down into target ranges as quickly as possible. Once the target range has been achieved, begin reducing the amount of medicine by half, or take it every other day. Recheck your cholesterol levels in one month. If they have stabilized or continued to improve, you may no longer need the medication. If the levels begin to rise again, return to previous dosage. If you are currently on a cholesterol-lowering drug, you must consult your doctor before discontinuing the medication.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=712) Gugulipid: Controlling cholesterol levels
Date:
July 27, 2005 03:49 PM
Gugulipid: Controlling cholesterol levels An ancient Indian plant contains a compound that can help reduce cholesterol as effectively as drugs, but without side effects. By Michael T. Murray, N.D. An ancient medicinal plant from India shows promise in the fight against heart disease. The mukul myrrh tree (Commiphora mukul) secretes a resinous material called gum guggul. The classic ayurvedic medical text, the “Suchruttasamhita,” describes guggul’s role in the treatment of obesity and other lipid (fat) disorders. Comprehensive scientific studies have investigated the clinical effectiveness of gum guggul in disorders of lipid (fat) metabolism. Specifically, researchers have studies this extract’s ability to support healthy cholesterol and triglyceride levels and promote weight loss. As a result of this research, scientists have developed a natural substance-gugulipid-that appears to be safer than many other cholesterol-lowering agents, including niacin. What is gugulipid? Gugulipid is the purified standardized extract of crude gum guggul (oleoresin). The active components of gugulipid are Z-guggulsterone and E-guggulsterone. Other components of gugulipid include various diterpenes, sterols, steroids, esters, and fatty alcohols. Gugulipid is preferred to crude gum guggul because it is safer and more effective. In early studies, gum guggul was linked with mild side effects such as skin rashes, gastrointestinal irritation and diarrhea. In contrast, no side effects have been reported with gugulipid. Apparently, the insoluble irritants of gum guggul are removed in the production of the soluble gugulipid. This just one example of how science is advancing in the efficacy of herbal therapy. Through careful scientific study, researchers developed a safer and superior form of natural plant medicine. Pharmacology Numerous scientific studies have shown gugulipid effectively supports healthy levels of cholesterol and triglycerides. Gugulipid supports low levels of LDL (“Bad”) cholesterol and high levels of HDL (“good”) cholesterol. HDL cholesterol has been shown to protect against heart disease caused by atherosclerosis or hardening of the arteries. Research indicated gugulipid itself appears to help reduce atherosclerotic plaques. Gugulipid has been shown to improve the heart’s metabolism and act as an antioxidant, protecting the heart against free radicals. Gugulipid appears to help inhibit platelet aggregation (clumping of red blood cells), an important factor in preventing stroke or embolism. According to research findings, gugulipid promotes the liver’s uptake of LDL cholesterol from the blood, thus increasing the liver’s metabolism of LDL cholesterol. This function accounts for gugulipid’s ability to support healthy cholesterol levels. Because of gugulipid’s effects on heart function and cholesterol, this natural compound appears to be especially useful for individuals with cardiovascular disease. In addition, guggulsterone appears to stimulate thyroid function. This steroid stimulating effect may account for some of gugulipid’s impact on lipid levels and weight loss. Clinical studies Gugulipid’s impact on cholesterol and triglycerides is quite startling. When the diet is supplemented with gugulipid, cholesterol levels typically drop 14 to 27 percent in four to twelve weeks, while triglyceride levels drop 22 to 30 percent. Those are extremely significant reductions. The effect of gugulipid on serum cholesterol and triglycerides compares favorably to that of lipid-lowering drugs. Clofibrate and cholestyramine lower cholesterol levels from six to 12 percent and 20 to 27 percent respectively, but are associated with some degree of toxicity. In contrast, no side effects have been reported with gugulipid. IN addition to the excellent safety demonstrated in human studies, gugulipid has been shown to be nontoxic in safety studies on laboratory animals. Dosage Appropriate dosage of gugulipid depends on its guggulsterone content. Clinical studies indicate that 500 mg of gugulipid with a guggulsterone content of 25 mg taken three times per day effectively supports healthy cholesterol and triglyceride levels.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=711) HDL and LDL Cholesterol
Date:
June 25, 2005 07:42 PM
HDL and LDL Cholesterol There are both “good” and “Bad” forms of cholesterol. The “good” form of cholesterol is found in the form of high-density lipoproteins (HDLs). The ‘bad” forms of cholesterol are the low-density lipoproteins (LDLs). The types of fats we eat influence how much and what type of cholesterol we make. Saturated fats are particularly good at raising low-density lipoprotein or LDL cholesterol. The more of this type of cholesterol we have floating around in our bloodstream, the greater our risk of developing atherosclerosis, heart attack and stroke. The more HDL cholesterol we have (high-density lipoproteins) the lower our risk of coronary heart disease. The liver is constantly trying to clear out the bad cholesterol by dumping it into the intestines. If we have sufficient amounts of the right kinds of fiber in our diet, our bodies dispose of cholesterol waste rather than reabsorbing it back into the blood stream. If we don’t eat sufficient amounts of the right kinds of fiber, the cholesterol waste is reabsorbed and adds to the toxic stress on the body—especially the liver. The obesity factor is emerging as much more important than previously thought.23, 24 New findings strongly suggest that even a relatively small amount of excess weight (between 10 and 20 pounds) can predispose one to the development of heart disease.25
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=495) FEARING FATS: There's Plenty of Cause Overview
Date:
June 25, 2005 07:34 PM
FEARING FATS: There's Plenty of Cause Overview A wealth of scientific evidence now exists which should have turned each and everyone of us into a fat “phobic.”1a-e In other words, virtually every health expert agrees that a high fat diet is directly linked to cardiovascular disease, various types of cancer and premature death. It’s no secret that excess dietary fat poses a tremendous health risk. The United States National Institutes of Health, the World Health Organization and many other scientific institutes have confirmed the frightening hazards of fat. Health proponents generally concur that excess fat can significantly shorten one’s lifespan. More than 10,000 medical papers are published every year dealing with obesity and cardiovascular disease, two of the most insidious killers of Americans. Western eating habits, which promote fatty, salty, sugary foods, have created massive widespread disease and tremendous suffering. Studies have shown that fat is the macronutrient associated with overeating -
------------------------------------ TABLE 1. Total fat grams in single servings.4 and obesity.2 In spite of this finding we are eating more fat and becoming fatter. The average absolute fat intake has increased from 81 to 83 grams per day over the last ten years.3 Our obsession with fatty foods has exacted an enormous toll in the form of rampant obesity, clogged arteries, hypertension, heart attack, stroke, breast cancer, etc. Many of us remain oblivious to the fat gram count of foods we routinely pop into our mouths, unaware that one fast food entree may contain more fat grams than one should consume in one given day. Take a good look at the following list of foods which have been assessed for fat content. Fast food has become a 20th-century sensation which continues to boom and expand throughout our society. Many of us literally exist on fast food, which is frequently also “fat” food. It’s no wonder so many of us “battle the bulge”, and have skyrocketing cholesterol counts. Our love affair with greasy, fried, rich, creamy foods has burdened our bodies with the dilemma of excess fat “baggage,” resulting in phenomenal amounts of money being spent on weight loss programs. Worse still, thousands of Americans are dying before their time or living extremely compromised lives only because they ingest too much fat. Why is this? The bottom line is that fats taste good!5 Many of us were raised on seemingly innocuous foods that are loaded with fat. Some of these include: macaroni and cheese battered fish sticks hot dogs cheese-filled casseroles pepperoni pizza burritos pancakes, waffles doughnuts pies and pastries ice cream candy bars ramen soup Fat is also a major ingredient in most of the snack food we constantly nibble on, including chips, crackers, cookies, and nuts. Check ingredient labels to find the fat gram content of most snack foods. You’ll be surprised to find out just how fatty these foods are. Even a healthy sounding food like a “bran muffin” can contain 36 grams of fat! No wonder they stay so “moist”. In addition to the above foods, fat can add wonderful flavor to breads, vegetables and the like, and is usually used liberally in the form of butter, sour cream, whipping cream, melted cheese, cream cheese spreads, dips, cream sauces, and gravies. Fruits can also be high in fats. Did you know that one avocado has 30 grams of fat? One half cup of peanuts contains 35 grams of fat and only one glazed doughnut has 13 grams of fat. The majority of research points to fat as a much more dangerous culprit than anyone might have imagined. Saturated fats such as lard, palm, coconut oil, and beef tallow are particularly menacing. Research scientists have found over and over again that fats can contribute to the growth of tumors in animal studies.6 The National Research Council of the National Academy of Sciences reported that even a relatively small amount of extra body fat increases the risk of certain diseases for women and may compromise their longevity.7 Even being mildly overweight may be much more risky than anyone previously assumed.8 The Relat ionship between Breast Cancer, Fat s, Fiber And Indoles
Dr. Leonard Cohen, of the Dana Institute of the American Health Foundation at Naylor, believes that pre-cancerous lesions found in breast tissue will develop into cancer only if they are stimulated by certain agents such as fat.9 Women increase their risk of developing breast cancer when they consume a diet high in fat and animal protein and low in fiber, vegetables and fruits. When women put on weight, they have a tendency to create more estrogen since adipose tissue produces estrogen. Certain forms of estrogen, the so-called “bad estrogens” can act as carcinogens and are anything but desirable.10 High or unbalanced estrogen levels stimulate concerous tissue in the breast. Obesity is also associated with increased breast cancer mortality.11 The three most important ways to inhibit “Bad” estrogen from inducing breast cancer are:
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Date:
May 09, 2005 06:10 PM
It's in the BloodNatural alternatives abound for managing cholesterol levels, backed by a growing body of research ©VR By Paul BubnyThe National Cholesterol Education Program (NCEP) last July lowered the threshold for considering the use of statin drugs—a move which some say was motivated more by profits than scientific evidence. For example, the Center for Science in the Public Interest pointed out that eight of the nine authors behind the new recommendations had financial ties to statin manufacturers, which stand to reap billions of dollars more from a category that grossed $14 billion in the U.S. last year. And though the Food and Drug Administration (FDA) in January decided against authorizing over-the-counter (OTC) sales of statin drugs, drug companies would still like to see this happen. “The medical establishment’s pushing of these drugs to becoming the number one category of prescribed drugs in the world has led them to keep lowering the total cholesterol number that triggers the drug recommendation,” said Neil E. Levin, C.C.N., D.A.N.L.A., nutrition educator, product formulator, and “Truth Advocate” for NOW Foods (Bloomingdale, IL), which produces a number of supplements for addressing cholesterol. “This is despite the lack of evidence that total cholesterol means much as regards cardiovascular risks. “Other tests are much more important in terms of predicting risks, including CRP (C-reactive protein), the balance of different cholesterol fractions, and homocysteine,” he continued. “Add adult-onset diabetes to the risk factors for cardiovascular disease (CVD).” At the same time, the allegation that enormous sales potential lay behind the lower threshold for prescribing statin drugs illustrates how widespread the problem of hypercholesterolemia (elevated total cholesterol) is. More than 100 million Americans have elevated cholesterol (total cholesterol values of 200 mg/dl and higher), and of these, more than a third have high cholesterol (levels of 240 mg/dl and higher), according to the American Heart Association. Those numbers have unfavorable implications for the incidence of CVD, as high cholesterol is considered a risk factor for coronary heart disease and stroke. While statin drugs haven’t garnered the same degree of negative publicity that COX-2 inhibitors have suffered lately, safety concerns have arisen nonetheless. For one thing, these drugs lower the liver’s production of coenzyme Q10 (coQ10) along with its production of cholesterol. “CoQ10 is related to energy production and immune functions, is an antioxidant, and [is] an important cardiovascular nutrient,” Levin said. “It is not good to lower one’s coQ10 levels by half!” Moreover, said Levin, statins increase the tendency of muscle tissues to break down. “Combined with inactivity or certain drugs, this can stimulate muscle wasting,” he said. “Muscle is where a good deal of calories are burned, so a loss of muscle could affect mobility and energy production, potentially adding to obesity problems. These muscle changes occurred in patients and persisted for years after treatment was discontinued, as shown by muscle biopsies, even if no obvious muscle problems were observed by the patients.” And the last word on the subject may not have been spoken. Predicted Dr. Frank King, Jr. president of King Bio Natural Medicine (Asheville, NC), “Once the appropriate studies are finished, these drugs, along with hypertensives, will hit the fan bigger than the COX-2 inhibitors.” Also looking toward the future, Levin said that of the 20 million Americans who will be “targeted” for statin drug prescriptions under the new NCEP guidelines, “Some of these will want to try natural methods first. Others will rebel at the side effects of the drugs and experiment with alternative products.” King and Levin both saw opportunity for natural products in the fallout from drug safety concerns, with King projecting that sales of his company’s cholesterol-related homeopathic remedies will double in 2005. “The reports of deaths from drugs will always overshadow the trumped-up studies and news reports blasting dietary supplements,” said Levin. “Vioxx knocked vitamin E off the media’s radar screens pretty rapidly, though we still see ignorant reporters citing that [Johns Hopkins] vitamin E analysis as if it were true. But the comparable safety of supplements means that open-minded people will want to at least try natural therapies before signing in to a lifetime of drug therapies. Meanwhile, the studies on natural products will continue to build our credibility.” Those studies keep coming in, with at least four major findings published in the past few months, plus a heart-health claim on walnuts authorized by FDA. They join a raft of earlier findings that link natural products—branded and otherwise—to healthy cholesterol levels.
"Blur of Products"With so many natural alternatives to cholesterol drugs available, it can be hard to keep track. “As with any other category, the blur of products as they cascade over several shelves means that the retailer needs to have a good sense of what works and what they want to recommend to their customers,” Levin said. “Really, each person needs a protocol that would include antioxidants, fiber, vitamins, herbs, and oils. The pre-mixed cholesterol support formulas are a good starting place.” To help retailers get a sense of “what works,” here is an alphabetical discussion of several nutrients that have demonstrated benefits in serum cholesterol levels. They include the following: Barley may help lower cholesterol, according to a report in the American Journal of Clinical Nutrition (2004, vol.80, no.5: 1185-1193). Twenty-five adults with mild hypercholesterolemia consumed a controlled diet low in total fat, saturated fat, and cholesterol for 19 weeks. They then added whole-grain products containing barley to their diets that contained low (0 g), medium (3 g), or high (6 g) amount of beta-glucan per day for five weeks. Total cholesterol was reduced by 4 percent 9 percent, and 10 percent, respectively. The diet with the highest amount of beta-glucan led to a decrease in LDL cholesterol of 17 percent. Chromium. There’s evidence, Levin said, that chromium in doses of 500 mg a day may decrease levels of low-density lipoprotein (LDL, the so-called “Bad” cholesterol) and total cholesterol while raising levels of high-density lipoprotein (HDL, or “good” cholesterol). At the annual meeting of the American College of Nutrition last October, a poster presentation on the safety of Benicia, CA-based InterHealth Nutraceuticals’ ChromeMate niacin-bound chromium won first prize; among other things, the presentation cited chromium’s role in maintaining healthy blood lipid levels. Fatty Acids. The latest in a long line of studies demonstrating the benefits of fatty acids in heart health is a study published in The International Journal of Clinical Pharmacology and Therapeutics in December 2004. It showed that docosahexaenoic acid (DHA), an omega-3 fatty acid, can restore normal blood vessel function in children with inherited high cholesterol. The study, which used Martek DHA produced from microalgae, concluded that restoration of normal blood vessel function has the “potential for preventing the progression of early coronary heart disease in high-risk children.” “The evidence continues to accumulate on the cardiovascular benefits of DHA for people of all ages,” said Henry “Pete” Linsert, Jr., chairman and CEO of Martek Biosciences, an ingredient supplier based in Columbia, MD. “This study clearly indicates that DHA played an important role in healthy blood vessel function in the children in this study.” On the Omega-Research.com Website maintained by fish oil manufacturer Nordic Naturals (Watsonville, CA) can be found summaries of several earlier studies linking omega-3 fatty acids to maintaining healthy blood lipid levels, as well as related benefits such as elasticity of the arteries. In a 2003 study published in the American Journal of Clinical Nutrition, it was found that women receiving a mixture of 4 g eicosapentaenoic acid (EPA) and DHA along with 2 g of gamma-linolenic acid (GLA) had lower levels of LDL cholesterol after 28 days compared to those who received either the EPA/DHA supplements without DHA, EPA/DHA with a smaller dose of GLA, or GLA alone. Flax is another source of omega-3s, and Arkopharma/Health From The Sun (Bedford, MA) offers FiProFLAX in a variety of forms. Marketing director Hugues P. Mas said the flax is “QAI [Quality Assurance International] certified organic and guaranteed GMO [genetically modified organism]-free.” On its Website, the company offers a cholesterol quiz geared to consumers, discussing the importance of omega-3s as well as other nutrients. Garlic. Adding to an already considerable body of research demonstrating that garlic can lower total cholesterol, LDL cholesterol, and triglycerides while increasing HDL cholesterol, researchers at UCLA in 2003 reported that Kyolic aged garlic extract reduced or inhibited plaque formation in the arteries of 19 cardiac patients taking statin drugs. Lead researcher Matthew Budoff, Ph.D. commented at the time that the study “suggests that aged garlic extract may be a useful and beneficial dietary addition for the people who have high cardiovascular risk or who have undergone heart surgery.” Budoff has since presented several trade show seminars sponsored by Los Angeles-based Wakunaga of America, the makers of Kyolic. Guggul. In use for centuries as a component of Ayurvedic medicine, guggul—a gummy resin tapped from the Commiphora mukul tree, which is native to India—has been studied since the early 1960s for its hypolidemic (blood-lipid lowering) properties. Sabinsa Corp. (Piscataway, NJ), an ingredient supplier which produces a standardized extract under the brand name Gugulipid, says the studies on guggul indicate that its hypolipidemic activity can be attributed to more than one mechanism of action. Among the possible mechanisms are: inhibition of cholesterol biosynthesis, enhancing the rate of excretion of cholesterol, promoting rapid degradation of cholesterol, thyroid stimulation, alteration of biogenic amines, and “high affinity binding and anion exchange.” Homeopathy. “Homeopathy activates the body’s own control system to work properly,” said King. “This is the safest and most curative approach to take. “Forcing the body into biochemical change even naturally doesn’t actually have the curative action of homeopathy,” King continued. “Homeopathy can even correct the genetic predispositions to disease we may have inherited from as deep as a thousand years into our family chain.” King Bio makes Artery/Cholesterol/BP, a homeopathic formula intended to help tone heart muscles and blood vessels. Low glycemic index foods. In a study published in the February issue of the American Journal of Clinical Nutrition, researchers found that high glycemic load is negatively correlated to serum levels of HDL cholesterol. Assessing the relationship between blood levels of lipids and diet in a test population of 32 healthy males and females ages 11 to 25, the researchers found that glycemic load accounted for 21.1 percent of the variation in HDL cholesterol. They concluded that glycemic load appears to be an important independent predictor of HDL cholesterol in youth and noted that dietary restrictions without attention to glycemic load could unfavorably influence blood lipids. Medicinal Mushrooms. Although its product SX-Fraction is intended primarily to address high blood sugar, Maitake Products, Inc. (MPI, Ridgefield Park, NJ) found in a clinical study that LDL cholesterol in diabetic patients declined modestly (from 142 mg/dl to 133 mg/dl) over a two-month period. Those taking SX-Fraction also lost about 7 lbs. in the same time period. “The more impressive lowering of cholesterol, however, comes from the dietary fiber that is found in all medicinal mushrooms,” said Ellen Shnidman, manager of scientific affairs at MPI. She cited animal studies which documented the cholesterol-lowering properties of four different mushrooms: maitake, shiitake, agaricus, and enokitake. For example, a study reported in the September 1996 issue of Alternative Therapies showed “a 44 percent reduction in total cholesterol in rats consuming maitake mushroom in their diet,” said Shnidman. “This cholesterol reduction is accompanied by weight loss, relative to rats eating a similar high-choelsterol diet without mushrooms. Apparently, cholesterol is excreted by the rats in sufficient quantity to aid in weight loss.” Oat bran. A 2004 consumer study conducted by the Natural Marketing Institute (NMI, Harleysville, PA) for Nurture, Inc. (Devon, PA), which produces the ingredient OatVantage, found that 63 percent of consumers managing their cholesterol levels prefer oat-based ingredients. Oat bran is the subject of a health claim authorized by FDA in 1999, and NMI research found that 69 percent of respondents preferred the FDA-permitted health claim, “Helps Lower Cholesterol,” over the model structure-function claim, “Helps Maintain Healthy Cholesterol Levels.” “This is significant for food, beverage, and dietary supplement manufacturers who want to increase sales by using a more consumer-desired claim on the product label,” said Griff Parker, Nurture CEO. Plant sterols. Also the subject of an FDA-approved claim for heart health, plant sterols (structurally similar to cholesterol in humans) can block the absorption of cholesterol, according to a number of studies. In an “Ask the Doctor” publication (available online at www.atdonline.org), Decker Weiss, N.M.D. noted that sterols enter the same receptor sites that cholesterol enters on its way to the bloodstream. “The cholesterol, being blocked from absorption, remains in our intestines where it is eventually excreted,” Weiss wrote. General Mills has just introduced Yoplait Healthy Heart, a yogurt high in plant sterols. Policosanol. A mixture of fatty alcohols derived from sugar cane or beeswax, policosanol has been favorably compared in clinical studies to several types of prescription drugs for managing cholesterol. On its own, policosanol was found in a 1999 study to reduce LDL cholesterol while raising levels of HDL cholesterol. Probiotics. “Several studies have indicated that consumption of certain cultured dairy products resulted in reduction of serum cholesterol, as well as triglycerides,” wrote Dr. S.K. Dash, president of probiotic manufacturer UAS Laboratories (Eden Prairie, MN), in his Consumer Guide to Probiotics. Among other studies, Dash cited two controlled clinical studies from the VA Medical Center at the University of Kentucky. “In the first study, fermented milk containing [Lactobacillus] acidophilus was accompanied by a 2.4 percent reduction of serum cholesterol concentration,” he wrote. “In the second study, a different L. acidophilus strain reduced serum cholesterol concentration by 3.2 percent. Since every 1 percent reduction in serum cholesterol concentration is associated with an estimated 2 to 3 percent reduction in risk for coronary heart disease [CHD], regular intake of fermented milk containing an appropriate strain of L. acidophilus has the potential of reducing risk for [CHD] by 6 to 10 percent.” Dash said his company’s DDS Probiotics contain DDS-1 L. acidophilus, “which has been researched and demonstrated to show cholesterol-lowering effect.” Psyllium. “Internal cleansing is very important” in maintaining healthy cholesterol levels, “especially if you do it with a lot of fiber,” said Sunil Kohli, vice president of Chino, CA-based Health Plus, Inc. The cholesterol-managing ability of fiber in general and psyllium in particular is “very well-established,” he said. However, Kohli said, “It will probably do you no good if it’s random. It should be done on a regular basis, and it should be supervised. Consulting the doctor or pharmacist is important.” Soy. The protein in soy “has evidence of lowering total cholesterol and LDL cholesterol, based on reviews of studies using over 20 g of soy protein per day,” said Levin. “Soy isoflavones are considered only partly responsible for this effect.” Sytrinol. A patented proprietary formula derived from natural citrus and palm fruit extracts and containing citrus polymethoxylated flavones and palm tocotrienols, Sytrinol has been shown in clinical trials to improve total cholesterol, LDL cholesterol, and triglycerides by up to 30 percent, 27 percent, and 33 percent, respectively. Having just wrapped up Phase III of a long-term trial of Sytrinol, Chicago-based SourceOne Global Partners, which owns the exclusive worldwide license for intellectual property associated with the ingredient, is commencing a study that combines Sytrinol with plant sterols. Tocotrienols. On its Website discussing the science and benefits of tocotrienols (www.tocotrienol.org), ingredient supplier Carotech Inc. (Edison, NJ) identifies several benefits for blood lipid levels. Tocotrienols, according to the Website, have been shown to “inhibit cholesterol production in the liver, thereby lowering total blood cholesterol;” “[suppress] hepatic HMG-CoA reductase activity [and result in] the lowering of LDL cholesterol levels;” and “inhibit cholesterogenesis by suppressing HMG-CoA reductase.”
New WeaponsThere are also nutrients that are emerging as potential weapons in the fight against cholesterol. Levin cited rice bran oil, resveratrol, pantethine, l-carnitine, and niacin as showing promise. With all of this, Levin said, it’s important for retailers to remember that “they are not allowed to discuss diseases and remedies unless there is an approved FDA health claim allowed on the label, as with soy protein and plant sterols. What is allowed are structure-function claims such as ‘cholesterol support,’ ‘promoting normal, healthy circulation,’ ‘homocysteine regulators,’ etc.” Supplementation is only one tool for managing cholesterol levels, manufacturers pointed out. “Besides nutrition, lifestyle is a key to controlling cholesterol,” Levin said. “Eating a variety of antioxidant-rich foods will prevent the liver from churning out cholesterol as a ‘cheap’ antioxidant. The body uses oxidized cholesterol to patch leaky and damaged blood vessels, so the ability to build healthy collagen is a must, using nutrients like vitamin C, Pycnogenol, rutin, hyaluronic acid, and MSM. “Don’t forget exercise and stress reduction,” he added. “Stress results in high cortisol levels—usually accompanied by poor blood lipid levels—and a lack of good sleep to produce unhealthy people.” VR Vitamin Retailer Magazine, Inc., 431 Cranbury Road, East Brunswick, NJ 08816 //www.oprmagazine.com/
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