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Scientists study the neuroprotective effects of fermented Curcuma longa L. (turmeric)
Date:
July 04, 2018 05:54 PM
Author: Darrell Miller
(support@vitanetonline.com)
Subject: Scientists study the neuroprotective effects of fermented Curcuma longa L. (turmeric)
Scientists study the neuroprotective effects of fermented Curcuma longa L. (turmeric) A recent Kristina University study suggests that fermented turmeric may help protect brain cells from being degraded by inflammation and oxidative stress. The same researchers found that fermented turmeric may also help protect against the impact of the amnesiac compound scopolamine. Researchers subjected scopolamine-treated mice to mazes and inflicted oxidative stress on rat brain cells to test whether fermented turmeric offered any protection. Preliminary results suggest that fermented turmeric could have value as an alternative or complementary treatment for neurodegenerative diseases symptoms. - Recent research has shown that fermented turmeric may be beneficial to the brain.
- Fermented turmeric has displayed properties that aid with memory conditions like Alzheimer's.
- Turmeric may also protect cells more generally from inflammation and other stress.
"It could serve as an alternative or complementary therapy for age-induced neurodegenerative diseases like Alzheimer’s disease." Read more: https://www.naturalnews.com/2018-07-02-scientists-study-neuroprotective-effects-of-fermented-curcuma-longa-turmeric.html
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Turmeric may reduce inflammation from osteoarthritis
Date:
November 01, 2017 12:59 PM
Author: Darrell Miller
(support@vitanetonline.com)
Subject: turmeric may reduce inflammation from osteoarthritis
Osteoarthritis is a condition affecting many people and without a cure, the condition turns lives upside down. Fortunately for sufferers, osteoarthritis inflammation and pain can be reduced with many at-home, natural remedies you probably already have lying around. Turmeric happens to be one of the remedies that works wonders for anyone who uses it and is suffering from this painful condition. Immediate inflammation relief is just one of the many benefits you enjoy when using turmeric for inflammation reduction. - extracts of turmeric reduces pain and in inflammation in osteoarthritis patients.
- Osteoarthritis is a chronic condition which is a huge burden on society.
- Taking non otc drugs (turmeric) which have the same effects could reduce unwanted side effects.
"A recent study published in the Journal of Medicinal Food demonstrated that extracts of turmeric have a significant impact on the inflammation and pain associated with osteoarthritis." Read more: http://www.dailyherald.com/entlife/20171028/turmeric-may-reduce-inflammation-from-osteoarthritis (abstract 3QD8LUVX4XZA4TAHSVDHDULDBL75XM 3LRKMWOKB5IAXBP22W460SUYLR42Z0 A1GGKSW85B9DYY)(authorquote 3IJ95K7NDXD38WLX7L9ZJPL4ZGCNG3 3URFVVM165JJHNY4LGEC6BPQ4IPUZC AD1ILDUXZHASF)(keypoints 3VGET1QSZ00A2XJA6JWS9VL2TPXW70 3TAYZSBPLL9DWZ3O74AY4ZXVYC8S2P A4DDYR5YAS4M2)
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Policosanol Cholesterol Complex
Date:
February 03, 2006 03:50 PM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: Policosanol Cholesterol Complex
Bio-Aligned Chart
Policosanol Cholesterol Complex Supports Healthy Lipid Levels Cholesterol Regulation--Serum and Liver Levels
The body uses various mechanisms to regulate cholesterol levels. Similarly, nutrients act in different ways. Policosanol acts at the level of cholesterol biosynthesis while beta sitosterol and green tea inhibit intestinal uptake of cholesterol and increase fecal bile secretion. Green tea reduces fat and cholesterol storage in the liver. Vitamin U acts at an enzymatic level. Curcumin (turmeric) helps maintain cholesterol levels within the normal range.
Cholesterol Breakdown and Elimination Certain ingredients support cholesterol breakdown and elimination via several pathways (such as elimination of bile). Bile, made by the liver to aid digestion, naturally contains cholesterol, some of which is removed through fecal excretion. Artichoke and dandelion support bile elimination. Myrcetin supports the uptake and removal of cholesterol from the bloodstream by white blood cells. Vitamin U activates an enzyme involved in cholesterol breakdown, according to animal studies.
HDL Regulation (High Density Lipoprotein) The proportions of different types of cholesterol (HDL/LDL) help determine healthy blood cholesterol. HDL cholesterol is responsible for transporting cholesterol away from peripheral tissues and carrying it back to the liver, where it can be eliminated. Increasing HDL relative to LDL can support cholesterol elimination and health.
Garlic, Myrcetin, turmeric, Chromium, Vitamin C
Heart and Circulation Unrestricted and smooth blood flow is critical to a healthy cardiovascular system. Ginkgo and policosanol support microcirculation and blood flow, while vitamin C promotes elasticity of vessels. Hawthorn is the premier cardiac tonic of Western herbalism. Green tea may help reduce fat storage in the heart.
Ginkgo, Green Tea, Hawthorn, Policosanol, Vitamins C and E, Niacin
Antioxidant Defense Cholesterol, although often viewed negatively, is essential for the integrity and stability of cell membranes, and the formation of hormones and bile salts. It is only when oxidation changes cholesterol's structure that arterial walls are affected. Antioxidants are crucial for protecting cholesterol from oxidation and maintaining healthy blood vessels. Particularly powerful antioxidants in this formula include policosanol, myrcetin, turmeric, green tea and vitamin E.
Ginkgo, Green Tea, Hawthorn, Myrcetin, Policosanol, turmeric, Vitamins C and E
Thyroid Gland A well functioning thyroid is essential for healthy metabolism, circulation and cholesterol levels. The thyroid regulates all aspects of metabolism, including heart rate. Gugulipid® supports thyroid function and aids the body's natural fat-burning mechanisms and release of stored fats. Kelp supplies iodine, an essential compound for production of thyroid hormones.
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Curcumin - Turmeric Extract
Date:
August 19, 2005 12:47 PM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: Curcumin - turmeric Extract
Curcumin
turmeric- History and Traditional Usage
Native to Southeast Asia, Curcuma longa is a tall tropical shrub with large oblong leaves and pale yellow flowers. The genus “Curcuma” belongs to the Zingiberaceae family, which includes ginger.1 The plant possesses a large root structure with fleshy, bulbous underground parts called “rhizomes.” These rhizomes, known as turmeric root, are harvested at maturity, dried and cured for commercial use. Chemical analysis shows that dried turmeric contains essential and volatile oils, with a curcuminoid content of 2.5 to 5.0 %.2
In addition to its popularity as a spice, turmeric is used as a dye for cloth and coloring agent in foods and cosmetics, thanks to its rich yellow color. turmeric also serves as a preservative, probably owing to the antioxidant and antimicrobial properties of curcumin. Extracts of Curcuma longa have demonstrated in vitro antibacterial and anti-fungal effects.3
turmeric is named in ancient Ayurvedic and Chinese herbal texts as a traditional folk remedy. Historically, turmeric was used externally for wounds, and sprains, and internally for digestive complaints, rheumatism, liver disorders, coughs and colds.4 Benefits
Protects cells and tissues by fighting free radicals.*
Supports joint function*
The numerous beneficial effects attributed to turmeric stem in large measure from the antioxidant properties of curcumin. Antioxidants neutralize free radicals, which are highly unstable molecules that can damage cellular structures through abnormal oxidative reactions. Curcumin is a potent “scavenger” of the superoxide radical, a free radical that initiates potentially harmful oxidative processes such as lipid peroxidation.5 Through this activity, curcumin has been shown to protect skin cells from the injurious effect of nitroblue tetrazolium, a toxin that generates superoxide radicals. Curcumin also increases survival of cells exposed in vitro to the enzyme hypoxanthine/xanthine oxidase, which stimulates superoxide and hydrogen peroxide production. Curcumin itself is not toxic to cells, even at high concentrations. Pure curcumin was shown to be less protective than a mixture of curcuminoids, indicating a possible synergism among curcuminoids.6 Because free radicals are involved in aging and exert harmful effects on skin, these results suggest curcumin may help slow skin aging.
Curcumin demonstrates several other in vitro effects linked to free radical scavenging. Curcumin scavenges nitric oxide, a compound associated with the body’s inflammatory response.7 Pure curcumin and turmeric extracts protect red blood cells from lipid peroxidation induced by hydrogen peroxide.8 Curcumin has been shown to protect DNA from oxidative damage, inhibit binding of toxic metabolites to DNA, and reduce DNA mutations in the Ames’ test.9 Although additional studies suggest an anticarcinogenic effect of curcumin, through protection of DNA,10 one in vitro study found that curcumin induced DNA damage in human gastric mucosal cells.11 It is speculated that curcumin may act as a pro-oxidant in the presence of transition metal ions such as copper and iron. (This is true for other antioxidants, including vitamin C.) Curcumin also demonstrates in vitro inhibition of COX-I and COX-II enzymes, which are involved in the inflammatory reaction.12 Together these results strongly suggest that curcumin is a potent bioprotectant with a potentially wide range of therapeutic applications.
Animal studies- In vivo protective effects
Through its free radical scavenging properties, curcumin has shown bioprotective effects in animals. In one study, rats were treated with isoproterenol, a chemical that causes cardiac hypertrophy (enlargement of the heart) due to abnormal collagen metabolism. Co-treatment with curcumin reversed the degradation of collagen and cardiac hypertrophy induced by isoproterenol.13 Curcumin protects mice from detrimental effects of radiation, by stabilizing the glyoxalase system, a biological system that regulates cell division.14 Curcumin protects livers of rats from the damaging effects of carbon tetrachloride (CCl4), a potent hepatoxin that injures the liver via its free radical metabolite, CCl3.15,16 Curcumin protected rats from alcohol-induced brain damage, in a study in which oral administration of curcumin reversed lipid peroxidation, reduced levels of free-radical metabolites and increased levels of glutathione, a major physiologic antioxidant.17 Curcuma longa extracts have shown anti-inflammatory effects in rats.18
Human Trials
Curcumin exhibits free-radical scavenging ability when administered to humans. In an open trial (uncontrolled), 18 healthy individuals ranging in age from 27 to 67 years consumed a Curcuma longa extract, at a dose supplying 20 mg curcuminoids, for 45 days. Before and after blood tests showed a statistically significant decrease in lipid peroxides.19 Preliminary trials have tested the anti-inflammatory action of curcumin, with results that verify the traditional use of turmeric as an anti-rheumatic herb. In a short-term double-blind, cross-over, comparative study, 18 people received curcumin (1200 mg daily) or phenylbutazone for two week periods. Both curcumin and phenylbutazone produced measurable improvements in joint flexibility and walking time. The subjects reported results only with phenylbutazone, which may be explained by the short duration of the trial.20 In a small placebo-controlled trial comparing curcumin to phenylbutazone, 45 patients with post-operative inflammation received curcumin, phenylbutazone or placebo. The anti-inflammatory effects of curcumin and phenylbutazone were comparable and superior to placebo.21 Curcumin has not been found to produce an analgesic (pain relieving) effect.
Bioperine-Nature’s Absorption Enhancer Boosts Curcumin Absorption*
Traditional Ayurvedic herbal formulas often include black pepper and long pepper as synergistic herbs. The active ingredient in both black pepper and long pepper is the alkaloid, piperine. Experiments carried out to evaluate the scientific basis for the use of peppers have shown that piperine significantly enhances bioavailability when consumed with other substances.22 Several double-blind clinical studies have confirmed that Bioperine® increases absorption of nutrients.23
Curcumin is poorly absorbed in the intestinal tract, limiting its therapeutic effectiveness. Oral doses are largely excreted in feces, and only trace amounts appear in the blood. Concomitant administration of 20 mg of piperine with 2 grams of curcumin increases the bioavailability of curcumin by 2000%.24
Scientific References
1. Majeed, M., Badmaev, V., Shivakumar, U., Rajendran, R. Curcuminoids. 1995. Piscataway, NJ: NutriScience Publishers. 2. Srimal, R.C. turmeric: a brief review of its medicinal properties. Fitoterapia 1997;68(6):483-93. 3. Ammon, H.P.T., Wahl, M.A. Pharmacology of Curcuma longa. Planta Medica 1991;57:1-7. 4. Snow, J.M. Herbal Monograph: Curcuma longa L. (Zingiberaceae). The Protocol Journal of Botanical Medicine, Autumn 1995:43-46. 5. Rao, N.S., Rao, M.N.A. Free radical scavenging activity of curcuminoids. Arzneim.-Forsch./Drug Res. 1996;46(2):169-171. 6. Bonté. F. et al. Protective effect of curcuminoids on epidermal skin cells under free oxygen radical stress. Planta Medica 1997;63:265-66. 7. Rao, S., Rao, M.N.A. Nitric oxide scavenging by curcuminoids. J Pharm. Pharmacol. 1997;49:105-7. 8. Lalitha, S., Selvam, R. Prevention of H2Os-induced red blood cell lipid peroxidation by aqueous extracted turmeric. Asia Pacific J Clin Nutr 1999;8(2):113-14. 9. Deshpande, S.S., Maru, G.B. Effects of curcumin on the formation of benzo[a]pyrene derived DNA adducts in vitro. Cancer Letters 1995;96:71-80. 10. Subramanian, M., et al. Diminution of singlet oxygen-induced DNA damage by curcumin and related antioxidants. Mutation Research 1994;311:249-55. 11. Blasiak, J., Trzeciak, A., Kowalik, J. Curcumin damages DNA in human gastric mucosa cells and lymphocytes. Journal of Environmental Pathology, Toxicology and Oncology 1999;18(4):271-76. 12. Ramsewak, R.S., DeWitt, D.L., Nair, M.G. Cytotoxicity, antioxidant, and anti-inflammatory activities of Curcumins I-III from Curcuma longa. Phytomedicine 2000;7(4):303-308. 13. Nirmala, C. Anand, S., Puvanakrishnan, R. Curcumin treatment modulates collagen metabolism in isoproterenol induced myocardial necrosis in rats. Molecular and Cellular Biochemistry 1999;197:31-37. 14. Choudhary, D., Chandra, D. Kale, R.K. Modulation of radioresponse of glyoxalase system by curcumin. Journal of Ethnopharmacology 1999;64:1-7. 15. Park, E-J. et al. Protective effect of curcumin in rat liver injury induced by carbon tetrachloride. J Pharm. Pharmacol. 2000;52:437-40. 16. Deshpande, U.R. et al. Protective effect of turmeric (Curcuma longa L.) extract on carbon tetrachloride-induced liver damage in rats. Indian Journal of Experimental Biology 1998;36:573-77. 17. Rajakrishnan, V. et al. Neuroprotective role of curcumin from Curcuma longa on ethanol-induced brain damage. Phytotherapy Research 1999;13:571-74. 18. Arora, R.B. Basu, N., Kapoor, V., Jain, A.P. Anti-inflammatory studies on Curcuma longa (turmeric). Indian J Med Res 1971;59(8):1289-95. 19. Ramirez-Bosca, A. et al. Antioxidant curcuma extracts decrease the blood peroxide levels of human subjects. Age 1995;18:167-69. 20. Deodhar, S.D., Sethi, R. Srimal. R.C. Preliminary study on antirheumatic activity of curcumin (diferoyl methane). Indian J Med Res 1980;71:632-34. 21. Satoskar, R.R., Shah, S J. Shenoy, S.G. Evaluation of anti-inflammatory property of curcumin (diferoyl methane) in patients with postoperative inflammation. International Journal of Clinical Pharmacology, Therapy and Toxicolgy 1986;24(12):651-54. 22. Atal, C., Zutshi, U., Rao, P. Scientific evidence on the role of Ayurvedic herbals on bioavailability of drugs. Journal of Ethnopharmacology 1981;4:229-232. 23. Bioperine®–Nature's Bioavailability Enhancing Thermonutrient. Executive Summary. 1996; Sabinsa Corporation, Piscataway, N.J. 24. Shoba, G., et al. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Medica 1998;64(4):353-6.
© 2002 Doctor's Best, Inc. Revised 8/13/02
*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
-- Vitanet ®
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MYELIN SHEATH SUPPORT™ - Herbal-Nutrient Nervous System Support!
Date:
June 04, 2005 10:15 AM
Author: Darrell Miller
(dm@vitanetonline.com)
Subject: MYELIN SHEATH SUPPORT™ - Herbal-Nutrient Nervous System Support!
Myelin Sheath Support
Planetary Formulas is pleased to introduce MYELIN SHEATH SUPPORT: a comprehensive formula designed to support the fat-like insulating sheath (myelin) that surrounds nerve tissues. Properly formed myelin is necessary for optimal nerve conduction. MYELIN SHEATH SUPPORT is the first formula developed for Planetary Formulas by herbalist and Ayurvedic specialist Alan Tillotson. It consists of some of the most highly regarded tonifiers of Chinese and Ayurvedic herbalism, along with additional key botanicals and supporting nutrients used with success in his practice.
Nervous System Support
MYELIN SHEATH SUPPORT is a broad-range herbal-nutrient formula that supports your nervous system with traditional Ayurvedic and Chinese botanicals as well as scientifically researched nutrients. Vitamin B-12 is key to the MYELIN SHEATH SUPPORT formula. It plays two critical roles: 1) it is essential for normal health of blood; and 2) it may function as a coenzyme in the synthesis of either the protein or lipid part of myelin.
Comprehensive Botanical - Nutrient Formula
Ayurvedic botanicals: Ashwagandha has been widely used throughout India for 3,000-4,000 years. It is one of the most highly regarded tonics in the 6,000-year old Ayurvedic tradition. Bacopa has been reported by Ayurvedic scholar Charaka to promote mental ability. Yogaraj guggul is one of the most valued botanical compounds of Ayurveda. The boswellic acids in boswellia inhibit leukotriene synthesis. Shilajit, a mineral resin that oozes from steep rocks in the Himalayas, is used extensively in Ayurveda. Curcuma (turmeric) has been used both internally and externally in Ayurveda. Curcuma is included in a dosage clinically shown to inhibit a group of enzymes that influence metabolism of arachidonic acid. Arachidonic acid is an unsaturated fatty acid found in most animal fats and is a precursor of prostaglandins. Chinese herbs: Included are the Chinese tonifiers panax ginseng and tienchi ginseng, as well as licorice extract (which is also prominent in European herbalism). MYELIN SHEATH SUPPORT delivers panax ginseng in amounts clinically shown to have adaptogenic (anti-stress) effects. Nutrients: Vitamin B-12, central for supporting the nervous system and specifically the myelin sheath, is included in the form of methylcobalamin. While a few forms of B-12 have been used clinically, it has been shown that methylcobalamin is a highly assimilable form of B-12, leading to increased retention in tissues. MYELIN SHEATH SUPPORT also includes zinc, copper, L-selenomethionine, boron, calcium, potassium, magnesium, chromium and pantothenic acid.
New Formulator!
Alan Tillotson is the newest member of the Planetary Formulas formulation team. He has been an ardent student of Ayurvedic herbalism, having engaged in an apprenticeship since 1976 with Ayurvedic scholar Mana Bajra Bajracharya, a practitioner whose family’s Ayurvedic lineage dates back 700 years. Planetary Formulas MYELIN SHEATH SUPPORT is available in bottles of 45, 90 and 180 tablets. Planetary Formulas: More than Herbs— Herbalism!
References Ammon, H.P.T. et al. 1993. Mechanism of antiinflammatory actions of curcumin and boswellic acids. J. Ethnopharmacology: 38:113. Bhattacharya, S.K. 1995. Activity of shilajit on alloxan-induced hyperglycaemia in rats. Fitoterapia LXVI, 4:328-332. Linder, M.C. 1991. Nutritional Biochemistry and Metabolism with Clinical Applications. 2nd ed. Norwalk: Appleton and Lange, 138-143.
-- VitaNet ® VitaNet ® Staff
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