Search Term: " Indiana "
Simpler CBD Legalization Bill Clears House Committee
January 28, 2018 07:59 AM
Cannabidiol, or cbd, was recently passed as a legal substance by the Indiana House of Representatives. The bill does have a curious ride that the cbd must contain less than 3% thc, or the active ingredient in marijuana to be legal. There may still be hurdles as it heads to the Senate, but this is clearly good. The best evidence came from a man suffering from ALS, who said it didn't cure him but it did give him better days than without the drug.
"A House committee passed legislation Wednesday to legalize cannabidiol, or CBD. The unanimously-approved bill takes a simpler approach to authorizing its use."
Read more: http://indianapublicmedia.org/news/simpler-cbd-legalization-bill-clears-house-committee-138811/
Cannabis bills making headway in the Statehouse
January 27, 2018 03:59 PM
Indiana lawmakers are advancing a bill which would allow study of the use of medical cannabis in that state. Last Thursday, they voted 94-0 to advance the bill towards passage. Additionally, they passed a second bill which would allow for the possession and sale of hemp in the state. Simultaneously, a number of other bills are under consideration regarding the use of different types of oils derived from cannabis. Given the different positions and number of bills under review, it seems that it will be some time before there is complete legal clarity on this topic in Indiana.
"Thursday morning, a House committee, passed a bill legalizing the sale and possession of hemp by a vote of 12 to 0. State Rep. Jim Lucas, a Republican from Seymour, said his House Bill 1137 includes CBD oil."
Read more: http://wane.com/2018/01/25/cannabis-bills-making-headway-in-the-statehouse/
Indiana senator files bill to legalize sale, possession of CBD oil
January 03, 2018 03:59 PM
Indiana is hoping to be one of the first states with legal access to CBD oil. Senator Jim Tomes from Wadesville out forth this legislation in hopes that it will open up this promising drug to all. The drug, derived from hemp, instead of the marijuana, is seen to be promising in many of its tests in a wide range of symptoms for its anti-inflammatory properties. The major change would just get rid of CBD from the controlled substance ban list for ease of use throughout the state.
"Republican Sen. Jim Tomes from Wadesville hopes to make the product readily available throughout the state."
Read more: http://www.wndu.com/content/news/Indiana-senator-files-bill-to-legalize-sale-possession-of-CBD-oil-467210573.html
Can your dog be arrested for using a cannabis extract?
December 16, 2017 03:59 PM
Thomas McDermott, a Democrat and the Mayor of Hammond, Indiana, brought up the legality of using cannabidiol oil (CBD) for treating his Labrador retriever's arthritis at the BGD Legislative Conference in Indianapolis. At the conference was Republican Indiana Attorney General Curtis Hill who last month stated that the use of CBD was illegal in most circumstances in his state after a bill passed to allow epilepsy patients to legally use the oil for seizures. McDermott questioned Hill using a story about his dog that suffered from arthritis, noting that his vet recommended using CBD oil to treat the pain. He mentioned that the oil allowed his dog to move around more easily, had more energy, and had improved appetite. McDermott thought aloud that Hill was "grandstanding" on CBD, but Hill simply stated he was following the law as it was written. When McDermott asked if his dog was breaking the law, Hill responded that the Mayor himself was breaking the law - not the dog. McDermott was upset afterwards that Hill accused him for being a criminal for treating his dog with CBD, and he has no plans to change the therapy for his dog.
"The question Thomas McDermott wanted answered Wednesday doesn’t get asked often during policy discussions in Indiana: Could his Labrador retriever be breaking the law by using a pain remedy extracted from cannabis?"
Read more: https://www.indystar.com/story/news/2017/12/13/can-your-dog-arrested-using-cannabis-extract/949429001/
Cannabidiol bill for epileptic seizures moves closer to becoming law
April 14, 2017 11:44 AM
Author Janet Williams writes about a bill in Indianapolis that would further the usage of medical marijuana for use among patients with epilepsy. The article lists the how the votes were cast and which side they favored. The author also makes a point to mention that the medical marijuana would be high CBD product rather than the typical form which contains majority THC, meaning that the medical product would not be for "getting high", but in fact would be medicine for epilepsy treatment with no psychoactive properties.
"Cannabidiol, or CBD is found in the seeds, stalk, and flowers of cannabis plants like hemp and marijuana. CBD has been found to minimize seizures in epileptic patients and has a negligible level of THC, the compound that creates the “high” feeling in marijuana."
Read more: http://thestatehousefile.com/cannabidiol-bill-epileptic-seizures-moves-closer-becoming-law/30969/
Say NO to GMO in America
December 05, 2016 10:18 PM
Coming from over 50 countries, countless millions of people have expressed their disapproval over attempted corporate ownership of plant seeds through GMO (genetically modified organisms). Having said that, the corporations involved have assured the public that GMO is safe and want us to believe that it's more efficient at feeding the world by giving higher yields and have greater resistance to extreme weather conditions.
Safety of GMOAccording to a growing number of scientists such as world leading expert Dr Don Huber GMO expert, professor of plant pathology at Purdue University, Lafayette, Indiana, USA, there has been NO peer reviewed evidence to support the idea that GMO crops are safe. On the contrary, a vast catalogue of scientific evidence has built up over the years showing that GMO is unsafe.
Public consumption of genetically modified crops have been accused of causing ill health in the form of allergies, cancer, birth defects and infertility. It also includes toxicity, reduced nutritional value, environmental damage and political unrest such as that with farmer's and consumer's disputes.
The Revolving Door EffectApproval bodies like the FDA (Food and Drug Administration) decide whether or not a food or drug is fit to go out on the market for consumption. GMO is not safe. Nor has it shown to produce higher yield, greater nutritional value or resist drought conditions better than non-GMO according to many experts such as Professor John Fagan, award-winning Geneticist, Maharishi University of Management, Iowa, USA.
Yes, of course we should say NO to GMO. It is spurred on by corporate greed and political self interest with more than its fair share of hidden ulterior motives. The technology is unimaginably potentially dangerous and could be perceived as one of the biggest threats to humanity if allowed to get out of control.
Why California Poppy is a Great Pain Reliever
March 31, 2012 07:49 AM
What Makes California Poppy So Good For Pain?
If you reside in California, chances are good that you are familiar with the California Poppy. Named as the state flower in 1903, the yellow poppy fields surround the bays as a sign that springtime is here. The botanical name is Eschscholtzia californica and this orange cup-shaped flower grows wild as an annual perennial in California and other southwestern states from April through August. It did not take long for settlers to realize that natural beauty was not all that the California Poppy had to offer.
The entire plant, from root and stem to leaves and seeds has been found to provide varying displays of physical and psychological healing properties. Although placed in the sub-opiate Papaver family, the yellow California Poppy is in no way an active source of opium as is its cousin, the red poppy. While the red poppy works to depress the central nervous system, the yellow poppy provides analgestic and antispasmodic chemical reactions that work on nerve and muscle pain.
For years, raw California Poppy root has been used as an immediate form of relief for toothache pain. By chopping off a segment of the root and applying directly to the source of the gum pain, instant relief is felt. This rare phenomenon is believed to be credited to the variety of benzophenanthridine alkaloids produced in the root. Many medical compounds such as morphine and codeine have been paralleled to this natural ingredient for the pain alterning state that is delivered. It is believed that only 20% of all plants contain this form of alkaloid that is known to relieve pain.
A Tincture for Pain
There are many organic sites that offer a tincture made from the roots and leaves of the yellow poppy. Fresh herbs that are compressed into concentrated form are found to be more effective than those that are dried. The active ingredients are mixed with an alcohol based liquid and used in a liquid or placed under the tongue. A measured amount can alleviate pain from menstrual cramping or intestinal discomfort. Anxiety or stress related headaches are also treated with tincture that reportedly gives relief within minutes. A tincture made with California Poppy has a shelf life of five years when stored in a cool, dark area.
Raising California Poppy
California Poppy is a wonderful way to add a splash of color around the outside of your house and also reap the benefits of the medicinal properties. The bright orange flowers love the sunshine and will stretch to find. You will be able to keep a natural pain reliever on hand for making tincture, extract or tobacco. Smoking California Poppy gives a relaxing way to end a hard day and relieve pressure and pain from sore muscles. Acting as a sedative, you will find yourself drifting off into a blissful sleep. California Poppy can also be used for restless leg syndrome and many have experience luck in treating ADD and other neurological problems.
Ever since the days of the native Indiana, California Poppy has helped to relieve pain occuring from different sources and remains a great healer to this day.
Folic acid enhances Chemotherapy
October 10, 2005 12:05 PM
Folic acid enhances Chemotherapy
Scientists have discovered that cancer cells have a natural attraction to folic acid. This safe constituent of vitamin B is now being used as a nontoxic “Trojan horse” to carry chemotherapy directly to various cancers. Researchers reported at the 4th annual Gene, Drug Therapy and Molecular Biology meeting that the vitamin can be used with conventional chemotherapy drugs and a variety of new gene therapies to destroy cancer cells.
Scientists have repeatedly found that folic acid is overexpressed in certain cancers: specifically, cancers of the ovary, cervix, endometrium, kidney, breast, brain, lung and colon. Scientists found that folic acid is especially overexpressed on tumors that are resistant to conventional chemotherapy. Dr. Philip Low of Purdue University and chief scientific officer at Endocyte, Inc. based in Lafayette, Indiana, told attendees that folic acid could become a perfect carrier for many types of tumor targeting. Endocyte researchers estimate that cancers that overexpress the folate receptor are diagnosed in about 300,000 people each year in the US.
This new specific targeting approach exploits cancer cells' insatiable appetite for folic acid. Compared to healthy cells, researchers say that cancer cells have 500,000 times greater affinity for folic acid. The folic acid that these cells ravenously seek can be used to target and deliver drugs to easy-to-find and hard-toreach cancer cells at the same time while avoiding normal, healthy cells. Folic acid does not trigger an immune response in the human body. It is readily available, easy to produce on large scale, and can be attached to a great number of drugs.
Botanical Arsenal - Plants can help our bodies fight off cancer's deadly ...
June 13, 2005 10:31 AM
Botanical Arsenal by Fred Thomas Energy Times, May 3, 1999
The complexities surrounding the various types of cancer stem from the variety of ways in which these diseases can wreak their havoc. Luckily, the equally complex world of plants contains novel compounds that can help our bodies fight off cancer's deadly progress.
Research into these botanical compounds is mushrooming. An example: The mighty maitake, a fungus with flair, alternately known as the king (it can grow as large as a basketball, worth its weight in silver to the ancient Japanese); the prince; the Hen of the Woods (it sticks out of from trees when it grows in the wild); and the dancing mushroom to those who leaped for joy when they found one growing in its native northeastern Japan.
Researchers today dub it with a new moniker: Herbal Heavyweight.
Mushroom with Potential
The maitake, with such other medicinal mushrooms as shiitake and reishi, historically has been eaten to promote general well-being and vitality. In the modern lab, however, scientists focus on the potent immune enhancing powers of maitake, which spotlight its cancer fighting potential.
Twenty years ago, maitake, Grifola frondosa, was an obscure, largely unavailable mushroom. A series of significant Japanese studies then catapulted it into prominence-and popularity.
Hiroaki Nanba, PhD, of the department of immunology at Kobe Women's College of Pharmacy on Kobe, Japan, and a leading international researcher on maitake, conducted the preliminary tests on the mushroom, demonstrating that it stimulates immune function and inhibits tumor growth.
In 1986, Dr. Nanba fed powdered maitake to mice injected with tumor cells; 86.3% displayed inhibited tumor growth.
Dr. Nanba and his colleagues went on to run additional mouse tests, finally reporting that this potent mushroom "directly activates various effector cells (macrophages, natural killer cells, killer T-cells, etc.) to attack tumor cells."
From then, maitake mushrooms were headed to fame as cancer ninjas.
Stoking The Immune Engine
Like other mushrooms, maitake is rich in complex polysaccharides, immunomodulators that successive tests after Dr. Nanba's have shown to be effective in cancer and AIDS treatment.
The polysaccharides in maitake have a unique structure, rendering them some of the most powerful to be studied (Chem Pharm Bull 1987:35:1162-8).
What makes maitake a particularly hot property is beta-D-glucan, its primary polysaccharide. Studies show that the body absorbs it readily, at which point it effectively stimulates interleukin-1, natural killer cells and macrophages, anti-tumor warriors that battle solid cancers (Chemotherapy 1990;38:790-6; also International Conference on AIDS, Amsterdam, 1992).
Effective And Safe
In addition to lab tests, trials on people have shown that maitake may offer powerful therapy against liver and stomach cancer (studies in China), breast and colon cancer (US research) and Kaposi's Sarcoma, the virulent cancer attacking AIDS sufferers.
Importantly, studies show that no side effects or interactions accompany maitake's efficacy.
Maitake fortunately has won the interest and enthusiasm of the scientific community. Currently, researchers at the Cancer Treatment Centers of America, headed by Denis Miller, MD, are completing an exhaustive test of the anticancer and immunostimulatory actions of maitake on folks with advanced colorectal cancer. These investigators hypothesize that the polysaccharide beta-glucans derived from the fruitbody of maitake fight tumors and boost immune function. "Though it cannot be said that maitake ...[is] the cancer cure," said Dr. Nanba in his closing remarks at the Adjuvant Nutrition in Cancer Treatment Symposium in Tampa, Florida, in October 1995, "one can safely say that they do maintain the quality of life of patients and improve the immune system, resulting in the possible remission of cancer cells with no side effects."
More Bodily Benefits
Maitake maven Dr. Nanba also has tested-with strongly positive results-the effect of maitake on blood glucose, insulin and triglycerides in mice, whose levels of all three substances declined when they were fed the mushroom (H. Nanba working paper, Anti-Diabetic Activity by Maitake Mushroom, 1994).
With colleagues, Dr. Nanba showed that maitake lowered blood pressure in hypertensive rats (Chem. Phann. Bu//36:1000-1006,1988). Other studies suggest it may accelerate weight loss.
This admirable adaptogen (meaning it helps the body adapt to stress and normalize its functions) is water soluble and may be eaten in food or taken as a supplement. Vitamin C is believed to intensify maitake's beta-glucans and enhance their absorption.
It's not just what you eat that may help protect against cancer, but what you drink as well. Research from China and Japan, where tea is the everyday drink and rates of several cancers like breast and prostate are lower, may persuade you to turn over a new leaf in your own beverage choice. One of the first studies to spark interest in tea came from Shanghai (Journal of the National Cancer Institute, June 1, 1994), where people who drank two to three cups a day were found to have about a 60% reduction in the risk of cancer of the esophagus. The reason: tea leaves contain compounds called polyphenols, potent antioxidants.
In fact, in tests at the University of Kansas, three of these, known as catechins, far outshone the common antioxidant vitamins C and E. Clinical trials are just starting, but early results are encouraging. A team of Chinese scientists reported that in a third of people with precancerous mouth sores who drank three cups of a mixture of green and black tea the lesions shrank significantly.
Researchers at the Saitama Cancer Center in Japan found that green tea seems to improve the prognosis of breast cancer. They followed a group of women with early-stage tumors for seven years. Those who drank more than five cups of green tea a day were only half as likely to suffer a recurrence as patients who consumed fewer than four cups a day.
And at the University of Indiana, toxicologist James Klaunig found that the lungs of cigarette smokers who drank the equivalent of six cups of tea a day suffered 40 to 50 percent less damage from the toxins in smoke, potentially lowering their risk of lung cancer and other pulmonary problems. Simultaneously, research from Purdue University suggests tea's cancer-discouraging powers go beyond being an antioxidant. Scientists Dorothy and D. James Morre showed that a tea catechin dubbed EGCG inhibits a growth-promoting enzyme on the surface of many cancer cells-happily without affecting normal cells. And researchers at the Ohio State University College of Medicine found that EGCG counteracted another enzyme, urokinase, that helps cancer cells spread. To top it off, Mayo Clinic scientists recently showed that EGCG prompted prostate cancer cells to commit suicide (Cancer Letters, Aug. 14, 1998).
So far, most tea research has focused on green tea, and investigators agree it's more potent than the black tea most Americans favor. But because both kinds come from the same plant, Camellia sinensis (it's the processing that makes the difference as black tea is fermented, green tea isn't) both contain cancer-fighting polyphenols, just in different quantities. As long as the tea you drink (even decaffeinated) is fresh brewed, it's likely to provide some benefit; powdered and prepared teas probably don't. And adding milk may dilute the effect.
Astragalus Against Tumors
Astragalus, an herb commonly used in Asia to boost stamina, has impressed western doctors for its potential for helping people cope with chemotherapy. As John Diamon, MD, W. Lee Cowden, MD and Burton Goldberg point out in the Definitive Guide to Cancer (Future Medicine), "Astragalus appears to protect the liver against the harmful toxic effects of chemotherapy and may be effective in treating terminally ill liver cancer patients." (They cite a study in the Jrnl of Ethnopharmacology 1990, 30:145-149.) In addition, they point out, research in Japan supports using a ginseng-astragalus combination to improve the function of natural killer (NK) cells which can boost immunity (Japanese Jrnl of Allergy, 37:2, 1998, 107-114).
Other studies confirm astragalus' potential in fighting off cancer. Research at the General Hospital of PLA, Beijing, showed that flavonoids (pigments) in astragalus could help protect cell membranes from oxidative damage caused by ultraviolet exposure (Chung Kuo Chung Yao Tsa Chih, 21(12):746-8; 1996 Dec).
A study of laboratory animals at Cunma University in Maebashi, Japan, found that Astragalus could help preserve immune function against the harmful side effects of chemotherapy (Chung Kuo Chung Hsi I Chieh Ho Tsa Chih, 15(2):101-3, 1995 Feb).
Like a flame attracting moths, garlic bulbs have irresistibly drawn the attention of medical researchers. A study at Aarhus University, Denmark, found that skin cells in laboratory dishes treated with garlic supplements lived longer, healthier lives than untreated cells (Jrnl Ethnopharm, 1994. 43:125-133).
Meanwhile, a long list of research demonstrates that garlic's phytochemicals may fight tumors and reduce the carcinogenicity of the pollutants and chemicals that assault us daily. A study in China reported in the American Journal of Chinese Medicine showed that garlic helped slow tumors in lab animals (1983, 11:69-73). Another study in the Journal of Nutrition found that compounds in garlic could "suppress the growth of human colon tumor cells" (126, 1355-1361).
Added to those benefits, Robert A. Nagourney, MD, reports in the Journal of Medicinal Food (1:1, 1998, 13-28), garlic may "modify the carcinogenicity of foodstuffs." In other words, studies show that garlic can make chemicals in foods like pork less likely to cause your cells to become cancerous. (Ind J Physiol Pharmacol, 39:347-353).
DNA, the stuff that genes are made of, face constant threats from free radicals, caustic molecules that can alter cellular structure and possibly cause genetic mutations that lead to cancer. But research into what are called oligomeric proanthocyanidins (OPC), flavonoids (pigments) derived from fruits vegetables, grape seed extract and the bark of maritime pine trees shows that OPC may be able to shield DNA from injury.
In particular, studies of a grape seed extract called Activin have demonstrated this substance can help liver cell DNA escape a destructive process called peroxidation (FASEB, 11:3, 2/28/97).
In these experiments, Activin demonstrated the ability to inhibit the growth of tumor cells as well as slow the replication enzymes of HIV viruses. This protective ability proved to be more potent than that of vitamin C, beta carotene and vitamin E.
What does the future promise to reveal? Scientists believe that many unexamined plants probably contain undiscovered phytochemicals that hold great potential for helping us fight the cancer epidemic.
Certainly, if the next few years produce as many results as the past decade, the next millennium will witness a long line of cancer-prevention discoveries. Before long, you should be able to take advantage of these potent substances.
As you gulp your garlic, tip your tea cup, mull your maitake, acquire Activin and await your astragalus, you may meditate on what may soon be added to our growing anti-cancer arsenal. Undoubtedly, scientists with a botanical bent will be uncovering more coveted anti-cancer secrets before too long.
Recognizing the Signs: Roadmap to a Healthy Heart
June 13, 2005 10:06 AM
Recognizing the Signs: Roadmap to a Healthy Heart by Louis McKinley Energy Times, January 2, 2004
From time immemorial, people have tuned into life's lessons that come from the heart. Sadly, times are changing: If you're like most inhabitants of today's harried world, you may be too distracted to detect important clues about your cardiovascular circumstances.
And while heart lessons may be more complicated than simply connecting the physiological dots, understanding those heart messages are imperative for improving and maintaining your heart health.
Every cell in your body relies on heart-powered blood flow to keep it supplied with nutrients, oxygen, hormones and other natural chemicals necessary for survival. Without that supply of life-giving substances, few cells in the body-including those within the heart itself-can survive very long.
And just as damage to a major roadway can cause mayhem with traffic patterns, damage to blood vessels and the heart can wreak a lumpy cardiovascular havoc that blocks the passage of blood and endangers your heart's well-being.
Your Heart Disease Chances
Within the last ten years, scientific research performed by investigators around the world has focused on the specific factors that most strongly influence your chances of developing heart disease and suffering either a heart attack or a stroke.
While much of your risk depends on your genetic inheritance and family history, several factors that determine your heart health are within your control.
The most important factors you can do something about include:
* Smoking: free radicals generated by burning tobacco causes significant damage to blood vessels and other cells
* Lack of exercise: the human body is designed for consistent, moderate physical activity; without exercise, the body slacks off in creating antioxidant protection for arteries
* Diabetes: when excess blood sugar persists, physiological processes begin that endanger the heart and arteries
* Cholesterol: when oxidized (a chemical process that has been compared to a kind of internal rusting), cholesterol can form artery-blocking plaque; antioxidant nutrients like vitamin C and natural vitamin E may help the body limit this process
* High blood pressure: excessive pressure within the blood vessels raises the risk of damage to the heart and arteries; a program of weight loss and exercise can help control blood pressure
* Being overweight: the extra body fat carried around your middle is linked to a greater risk of heart problems
Heart Attack Signs
Do you think you know what a heart attack feels like? Well, if you think it feels like a dramatic pain somewhere in your chest that knocks you to the floor, you're probably wrong. "Most heart attacks do not look at all like what one of my colleagues calls the 'Hollywood' attack-the heart attack you see on television or in the movies," warns Julie Zerwic, MD, professor of surgical nursing who has studied what happens when people develop heart disease and suffer damage to their hearts.
"The symptoms [of heart problems] are not necessarily dramatic. People don't fall down on the floor. They don't always experience a knife-like, very sharp pain. In fact, many people describe the sensation as heaviness and tightness in the chest rather than pain," she says. And, if you're a woman experiencing a heart attack, you may not even feel discomfort specifically in your chest. Instead you may experience a severe shortness of breath. The apparent ambiguity of the discomforts caused by a heart attack lead many people to either ignore them or take hours to realize they need to go to the emergency room at the hospital.
Consequently, much fewer than half of all individuals undergoing a heart attack actually go to a hospital within an hour of the start of the attack. That delay can be a fatal mistake.
"Timing is absolutely critical," laments Dr. Zerwic. "If treatment starts within a hour after the onset of symptoms, drugs that reestablish blood flow through the blocked coronary artery can reduce mortality by as much as 50%. That number drops to 23% if treatment begins three hours later. The goal is to introduce therapy within two hours."
However, in Dr. Zerwic's research, only 35% of non-Hispanic whites go to the hospital within an hour of the start of a heart attack. And among African-Americans, the number of people going to the hospital right away drops to a frighteningly low 13%.
Often, people will lie down or use a heating pad to relieve the tightness they feel in the chest," says Dr. Zerwic. "They may take some medicine and wait to see if that works. All these steps postpone needed treatment."
Signs of a possible heart attack include:
* Chest discomfort: Heart attacks most frequently cause discomfort in the center of the chest that can either go away after a couple of minutes (and come back) or persist. The discomfort may feel like strong pressure, fullness or pain.
* Upper body discomfort: An attack may set off pain or discomfort in either or both arms, and/or the back, neck, jaw or stomach.
* Shortness of breath: Chest discomfort is frequently accompanied by shortness of breath. But it's important to note that shortness of breath can take place even in the absence of chest discomfort.
* Other signs: You can also break out in a cold sweat, or feel nauseated or light-headed.
A Woman's Sleep Signs
If you are a woman who suddenly experiences a marked increase in insomnia and puzzling, intense fatigue, you may be in danger of an imminent heart attack.
In an attempt to understand how women's symptoms of heart problems differ from those of men, researchers talked to more than 500 women in Arkansas, North Carolina and Ohio who had suffered heart attacks. (Technically, what they had experienced is referred to as acute myocardial infarction.)
They found that chest pain prior to a heart attack was only reported by about 30% of the women surveyed.
More common were unusual fatigue, sleep disturbances and shortness of breath (Circulation Rapid Access, 11/3/01).
"Since women reported experiencing early warning signs more than a month prior to the heart attack, this [fatigue and sleep problems] could allow time to treat these symptoms and to possibly delay or prevent the heart attack," says researcher Jean C. McSweeney, PhD, RN, nursing professor at the University of Arkansas for Medical Sciences in Little Rock. In Dr. McSweeney's study, more than nine out of ten women who had heart attacks reported that they had had new, disturbing physical problems more than a month before they had infarctions.
Almost three in four suffered from unusual fatigue, about half had sleep disturbances, while two in five found themselves short of breath.
Other common signs included indigestion and anxiety.
"Women need to be educated that the appearance of new symptoms may be associated with heart disease and that they need to seek medical care to determine the cause of the symptoms, especially if they have known cardiovascular risks such as smoking, high blood pressure, high cholesterol, diabetes, overweight or a family history of heart diseases," says Dr. McSweeney.
Dr. McSweeney warns that, until now, little has been known about signs that women are having heart trouble or heart attacks. The fact that most of Western medicine's past attention has been on heart problems in men has obscured the warning signs in women. As part of Dr. McSweeney's studies, she and her fellow researchers have discovered that more than 40% of all women who suffer a heart attack never feel any chest discomfort before or during the attack.
"Lack of significant chest pain may be a major reason why women have more unrecognized heart attacks than men or are mistakenly diagnosed and discharged from emergency departments," she notes. "Many clinicians still consider chest pain as the primary symptom of a heart attack."
Vitamins for Diabetes and Heart Disease
Having diabetes significantly raises your chance of heart disease, which means that keeping your blood sugar levels under control can reduce your chances of suffering a heart attack.
Today, 17 million Americans have diabetes and, as the country's population in general gains weight and fails to exercise, the number of people suffering this problem continues to grow.
The first line of defense against diabetes consists of exercise and weight control. All you have to do is take a brisk walk for 30 minutes a day to drop your chances of diabetes (American Journal of Epidemiology 10/1/03).
"We have found that men and women who incorporate activity into their lifestyles are less likely to develop type 2 diabetes than those who are sedentary. This finding holds no matter what their initial weight," said Andrea Kriska, PhD, professor of epidemiology at University of Pittsburgh Graduate School of Public Health.
To help your body fight the development of diabetes, researchers also recommend vitamin C and natural vitamin E.
Researchers working with lab animals at the University of California at Irvine have found that these antioxidant vitamins can help insulin (the hormone-like substance secreted by the pancreas) reduce harmful blood sugar. In addition, these vitamins shrink the chances of organ damage that can be caused by diabetes (Kidney International 1/03).
In this investigation, these vitamins also helped reduce blood pressure, another risk factor that raises heart disease risk.
"Blood pressure was lowered to normal, and free radicals were not in sufficient numbers to degrade the sugars, proteins and nitric oxide," notes Nick Vaziri, MD, professor of medicine at the University of California. "We think this shows that a diet rich in antioxidants may help diabetics prevent the devastating cardiovascular, kidney, neurological and other damage that are common complications of diabetes."
Free Radical Blues
Dr. Vaziri and his group of researchers found that untreated diabetes raised blood pressure and increased the production of free radicals, caustic molecules that can damage arteries and the heart. Free radicals can change blood sugar and other proteins into harmful substances, boosting tissue and heart destruction.
In Dr. Vaziri's work with lab animals, he found that treating diabetes with insulin lowered blood pressure and helped keep sugar and protein from changing into dangerous chemicals, but allowed the free radicals to subvert nitric oxide, a chemical the body uses to protect itself from free radicals.
In this investigation, adding vitamins C and E to insulin insulated the body's sugars, proteins and nitric oxide from oxidative assault. This produces a double advantage: Lowering the risk of heart disease and other damage to the body from diabetes.
Maitake, an Oriental mushroom that has been shown to have many health benefits, can also be useful for people with diabetes who are trying to avoid cardiovascular complications. Laboratory studies in Japan demonstrate that maitake may help lower blood pressure while reducing cholesterol (Biological & Pharmaceutical Bulletin 1997; 20(7):781-5). In producing these effects, the mushroom may also help the body reduce blood sugar levels and decrease the risk of tissue damage.
Tobacco smoke is one of the most notorious causes of heart problems. In the same way a hard frost exerts a death grip on a highway, the smoke from cigarettes can freeze up arteries and hamper their proper function. A healthy artery must stay flexible to comfortably allow adequate circulation.
But "...when blood vessels are exposed to cigarette smoke it causes the vessels to behave like a rigid pipe rather than a flexible tube, thus the vessels can't dilate in response to increased blood flow," says David J. Bouchier-Hayes, MD, professor of surgery at the Royal College of Surgeons in Ireland, who has studied the deleterious effects of tobacco.
This rigidity is called endothelial dysfunction. When arteries are rigid, blockages gum up vessels, clots and other impediments to blood flow appear, and your risk of heart attack and stroke increases (Circulation 2001 Nov 27; 104(22):2673).
This condition can also cause chest pain (angina) similar to that caused by a heart attack, and should be evaluated by a knowledgeable health practitioner.
Although all experts recommend you stop smoking to lower your heart disease risk, some studies have found that Pycnogenol(r), a pine bark extract that helps the body fight inflammation, may ease some of smoking's ill effects.
In a study of platelets, special cells in the blood that can form dangerous blood clots, researchers found that Pycnogenol(r) discouraged platelets from sticking together (American Society for Biochemical and Molecular Biology 5/19/98). By keeping platelets flowing freely, this supplement may alleviate some of the heart-threatening clots that tobacco smoke can cause.
In Ayurvedic medicine, a traditional therapy from India, an herb called guggul has also been used to lower the risk of blockages in arteries. This herb, derived from the resin of the mukul tree, has been shown to reduce cholesterol by about 25%. People taking this herb have also reduced their triglycerides (harmful blood fats) by the same amount (Journal Postgraduate Medicine 1991 37(3):132).
The Female Version of Heart Disease
For one thing, women often don't suffer from the crushing chest pain that for most people characterizes a heart attack; instead, many women experience back pain, sweating, extreme fatigue, lightheadedness, anxiety or indigestion, signs that can be easily misread as digestive troubles, menopausal symptoms or indicators of aging.
The genders also differ in how heart disease poses a threat. While men seem most endangered by the buildup of blockages in arteries, women apparently are more at risk from endothelial dysfunction. But more study needs to be done since, in many cases, researchers have been unable to pin down the precise mechanism that causes many women to die of heart disease.
Scientists have found that the number of women in their 30s and 40s who are dying from sudden cardiac arrest is growing much faster than the number of men of the same age who die of this cause. But research by the Oregon Health & Sciences University and Jesse E. Edwards Cardiovascular Registry in St. Paul, Minnesota, shows that while doctors can pinpoint the coronary blockages that kill men, they can't find specific blockages in half of the female fatalities they have studied (American Heart Journal 10/03).
"This was an unexpected finding. However, the study underscores the need to focus on what is causing these younger women to die unexpectedly because the number of deaths continues to increase," says Sumeet Chugh, MD, a medical professor at Oregon.
Since the failure of arteries to relax probably contributes to heart disease in many women, eating red berries, or consuming supplements from berries such as chokeberry, bilberry or elderberry, may be important in lowering women's heart disease risk. These fruits help arteries expand and allow blood to flow freely.
Red berries are rich sources of flavonoids, polyphenols and anthocynanins. The anthocyanins are strong antioxidants that give the berries their color. Research at the Indiana University School of Medicine have found that these chemicals can interact with nitrous oxide, a chemical produced by the body, to relax blood vessels (Experimental Biology conference 5/20/02).
As researchers work to devise lifestyle roadmaps that can steer you around the perils of heart disease, they are finding that exercise is a key path to avoiding cardiovascular complications.
A 17-year study of about 10,000 Americans found that those who exercised and kept their weight down (or took weight off and kept it off) experienced a significantly lower risk of heart problems (Preventive Medicine 11/03).
"The fact is that those who both exercised more and ate more nevertheless had low cardiovascular mortality," says Jing Fang, MD, of the Albert Einstein College of Medicine in the Bronx, New York. Burning calories in physical activity may be the secret to reducing heart disease risk and living longer, she says.
Dr. Fang's research used information collected from the First National Health and Nutrition Examination Survey in 1975 and then computed how much people exercised, how their body mass indices varied and which of these folks died of heart disease during the next two decades.
In the study, more than 1,500 people died of heart disease. Those who worked out and consumed more calories cut their risk of heart disease death in half.
Exercise Is Essential
"Subjects with the lowest caloric intake, least physical activity, and who were overweight or obese had significantly higher cardiovascular mortality rates than those with high caloric intake, most physical activity, and normal weight," Dr. Fang notes. The individuals in the study who were overweight and didn't exercise had a bigger risk of heart disease even if they tried (and succeeded) at eating less.
"This suggests that heart disease outcome was not determined by a single factor, but rather by a compound of behavioral, socioeconomic, genetic and clinical characteristics," according to Dr. Fang.
According to researchers, if your job requires a great deal of physical activity, your health will be better if you get another job. Exercise on the job not only doesn't decrease your risk of heart disease, it may actually raise it. The reason: On-the-job activity is linked to heart-endangering increases in job stress.
Research into this subject, performed at the Keck School of Medicine of the University of Southern California, found that while recreational exercise slowed hardening of the arteries, workers who had to exert themselves during the workday had arteries that were blocked at a younger age (American Journal of Medicine 7/03).
In this study, researchers examined about 500 middle-aged employees as part of what is called the Los Angeles Atherosclerosis Study.
"We found that atherosclerosis progressed significantly faster in people with greater stress, and people who were under more stress also were the ones who exercised more in their jobs," says James Dwyer, PhD, professor of preventive medicine at the Keck School. According to Dr. Dwyer, "This suggests that the apparent harmful effect of physical activity at work on atherosclerosis-and heart disease risk-may be due to the tendency of high-activity jobs to be more stressful in modern workplaces.
"It appears from our findings that the psychological stresses associated with physically active jobs overcomes any biological benefit of the activity itself."
On the other hand, the scientists found that heart disease drops dramatically among those who exercise the most in their spare time. In the study, people who vigorously worked out at least three times a week had the lowest risk. But even those who just took walks enjoyed better heart health than people whose most strenuous activity was working the TV remote. Dr. Dwyer says, "These results are important because they demonstrate the very substantial and almost immediate-within one or two years-cardiovascular benefit of greater physical activity."
Lowering your risk of heart disease is substantially up to you. Listen to what your heart tells you it needs; then, exercise your right to fetch some cardiovascular necessities.
June 10, 2005 09:44 PM
Breast Cancer by Joseph L. Mayo,MD Mary Ann Mayo, MA Energy Times, May 2, 1999
What do you fear most? Bankruptcy? Floods? Heart disease? If you're like many women, breast cancer stands near the top of that dreaded list.
But that fear doesn't permeate other cultures the way it does ours.
A woman like Mariko Mori, for instance, 52 years old, Japanese, worries about intense pressures beginning to burden her toddler grandson. But worry about breast cancer? Hardly.
In Indiana, Mary Lou Marks, 50, has similar family frets, mulling over her 28-year-old daughter's career choice.
But on top of that, when Mary Lou tabulates her other worries, she recoils at the thought of breast cancer. She's heard about her lifetime risk: 1 in 8. Meanwhile, Mariko's is merely 1 in 40, according to Bob Arnot's Breast Cancer Prevention Diet (Little, Brown).
New studies have found the effect of carrying the gene linked to breast cancer, which is responsible for only 5 to 10% of breast cancer incidence, is not as great as first suspected. Earlier estimates that the gene reflects an 80% chance of incurring breast cancer by age 70 has been recalculated to be only 37% (The Lancet, 1998;352:1337-1339).
Complex Causesbr> Researchers agree: No one factor is solely responsible for breast cancer. Risk depends on many factors, including diet, weight, smoking, alcohol consumption, activity level and, of course, those genes.
Regardless of their actual chance of getting breast cancer, women worry. Mary Lou faces no factors that would place her in particular jeopardy. But her anxieties about radical therapies and medical expenses paralyze her: She forgets to visit her health care provider and skips her annual mammogram appointments. Mary Lou's daughter, perhaps in reaction to her mother's gripping fears, campaigns ardently for cancer prevention, educating herself and mobilizing against the cumulative effects of known cancer risks. Smart young woman: A malignancy, after all, can take years to develop. A tumor must swell to one billion cells before it is detectable by a mammogram.
The soy-rich regimen of Japanese women like Mariko Mori, for example, helps to explain the low breast cancer rates in Asian countries (see box at center of the page).
Tomatoes, because of their high quotient of the carotenoid lycopene, have been found to protect cells from the corrosive clutches of oxidants that have been linked with cancer in 57 out of 72 studies (The Santa Rosa Press Democrat, February 17, 1999, page A6, reporting on a Harvard Medical School study). For more on tomatoes see page 16.
But there's no one magic anti-cancer food or diet. Eating to prevent breast cancer requires a balanced menu with fiber, healthy fats, phytoestrogens and antioxidants, all fresh and free of chemical additives.
Modifying the balance and type of estrogen, the female sex hormone produced by the ovaries, offers an important breast cancer safeguard. Fat cells, adrenal glands and, before menopause, the ovaries, produce three "flavors" of estrogen, the strongest of which, estradiol, is believed to be carcinogenic when too plentiful or persistent in the body.
Estrogen does its work by attaching to estrogen receptors. Receptors are particularly numerous in the epithelial cells that line milk sacs and ducts in the breasts.
A receptor site is like a designated parking spot: Once estrogen is parked there it triggers one of its 400 functions in the body, from preparation of the uterus for pregnancy to intensifying nerve synapses in the brain.
The food we eat can be a source of estrogen; plant estrogens, called phytoestrogens, are much weaker than the body's estrogens, but they fit the same receptors. Phytoestrogens exert a milder estrogenic effect than bodily estrogen and are capable of blocking the more potent, damaging versions.
Soy also contains genistein, an "isoflavone" very similar in molecular form to estrogen but only 1/100,000 as potent. Because of its structure, genistein can attach to cells just as estrogen does; it also helps build carriers needed for binding estrogen and removing it from the body (Journal of Nutrition 125, no.3 :757S-770S). It acts as an antioxidant to counteract free radicals.
Soy is most protective for younger women. Postmenopausal women benefit from soy's ability to diminish hot flashes and for cardiovascular protection, especially in combination with vitamin E, fiber and carotene (Contemporary OB/GYN, September 1998, p57-58).
Experts don't know that much about the cumulative effect of combining hormone replacement with soy, herbs and a diet high in phytoestrogens. Menopausal women who boost their estrogen this way should work with their health care providers and monitor their hormonal levels every six to 12 months with salivary testing.
The Vegetable Cart
Fiber from fruits, vegetables and whole grains reduces insulin levels and suppresses the appetite by making make us feel full, thus helping with weight control, so important to resisting cancer. Fiber also helps build estrogen carriers that keep unbound estrogen from being recirculated and reattached to the breast receptors.
Cellulose, the fruit and vegetable fiber most binding with estrogen, also rounds up free radicals that damage DNA within cells.,p> Feeding the Immune System Despite heightened public awareness and efforts to stick to wholesome, healthful diets, experts increasingly link poor nutrition to depressed immune systems. Many Americans are at least marginally deficient in trace elements and vitamins despite their best attempts to eat well; that's why a good multivitamin/mineral is wise, even mandatory. Vitamins given to people undergoing cancer treatment stimulate greater response, fewer side effects, and increased survival (International Journal of Integrative Medicine, vol. 1, no. 1, January/February 1999).
Nutrients tend to work synergistically on the immune system. They should be taken in balanced proportions, and in consultation with your health care provider.
n Riboflavin (B2), pyridoxine (B6), pantothenic acid (B5), zinc and folate strengthen immunity. Selenium, in lab culture and animal studies, has helped kill tumors and protect normal tissues.
n Beta-carotene and vitamins A, E and C are antioxidants. Vitamin C enhances vitamin E's effects, boosting immunity and protecting against cell damage. The antioxidant isoflavones in green tea, with soy, convey the anticancer effects of the Asian diet. Research shows actions that discourage tumors and gene mutations.
The food you eat influences hormones. Excess sugar raises insulin, which acts as a growth factor for cancer and interferes with vitamin C's stimulation of white blood cells. It may contribute to obesity.
Alcohol is converted to acetaldehyde, which causes cancer in laboratory animals. It affects gene regulation by decreasing the body's ability to use folic acid. It increases estrogen and the amount of free estradiol in the blood. The liver damage that accompanies high alcohol consumption frequently reduces its capacity to filter carcinogenic products, regulate hormones and break down estrogen. Studies of alcohol consumption have caused experts to estimate that drinking more than two alcoholic beverages a day increases breast cancer risk by 63% (OB-GYN News, November 1, 1998, p. 12).
Fat Can be Phat
Fat cells produce estrogen. Excess fat stores carcinogens and limits carriers that can move estrogen out of your system.
Once estrogen has attached itself to a receptor, the health result depends on the type of fat in the breast. Saturated fat, transfatty acids and omega-6 fat from polyunsaturated vegetable oils such as safflower oil, peanut, soybean oil, corn oil and in margarine can increase the estrogen effect and trigger a powerful signal to the breast cell to replicate.
Breast tissue is protected by omega-3 fat chiefly from fish and flaxseed and by omega-9 from olive oil. Salmon once a week or water packed tuna three times a week are particularly beneficial. Fish oil supplements processed to reduce contaminates are available. Cod liver oil isn't recommended: its vitamin A and D levels are too high.
Flaxseed is the richest known plant source of omega-3. Use a coffee grinder to benefit from the seed and oil for the full estrogen effect; sprinkle ground flaxseed over cereal or fold into baked goods. Drizzle flaxseed oil, found in the refrigerator section of your health food store, over salads or cereal. (Store the oil in the refrigerator.)
Olive oil, especially in the context of the so-called Mediterranean diet of vegetables, omega-3-rich fish and fresh fruit (Menopause Management, January-February 1999, p. 16-19), lowers the risk of breast cancer (The Lancet, May 18, 1996;347:1351-1356).
Selecting Organic Food
Buy or grow fresh, organic foods whenever you can. When grilling meat, fish or poultry, reduce the area where carcinogens may accumulate by trimming fat. Charred, well-done meat is known to be carcinogenic. When grilling, marinate meat first and reduce the cooking time on the grill by slightly precooking.
Cancer prevention is an interlocking puzzle requiring the limitation of fat consumption, weight control, exercise, stress reduction and care for psychological and spiritual balance. Possessing more cancer fighting pieces makes you more likely to be able to complete the prevention picture.
Joseph L. Mayo, MD, FACOG and Mary Ann Mayo, MA, are the authors of The Menopause manager: A Safe Path for a Natural Change, an individualized program for managing menopause. The book's advice, in easy-to-understand portions, isolates in-depth explanations with unbiased reviews of conventional and alternative choices. A unique perspective for mid-life women who want to know all their options.
Also from the Mayos - The HOW Health Opportunities For Women quarterly newsletter to help women learn HOW to make informed health choices. Learn HOW to: - Choose nutritional supplements