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What Cellular Mitochondria Does in the Body
Date:
April 28, 2022 04:19 PM
If you want to stay healthy, it's important that you know what cellular mitochondria does in the body. Mitochondria are organelles found in the cytoplasm of cells. They are responsible for producing energy for the cell. Without them, the cell would not be able to function properly. We will discuss the role of mitochondria in the body, and how they impact our health. What are mitochondria and what do they do in the body Mitochondria are organelles that play an important role in the energy metabolism of cells. Most of the oxygen we breathe is used by mitochondria to convert glucose from the food we eat into ATP, the energy molecule used by our cells. Therefore, mitochondria are often referred to as the "powerhouses" of the cell. In addition to producing ATP, mitochondria also have other important functions, such as regulating cell growth and death, as well as calcium homeostasis. Mitochondria are unique in that they have their own DNA separate from the DNA in the cell nucleus. This mitochondrial DNA is passed down from mother to child, which is why defects in mitochondrial function can lead to diseases that are inherited in a maternal lineage. Although most of our cells contain only a single nucleus, they may contain hundreds or even thousands of mitochondria. This allows them to produce enough ATP to meet the energy needs of the cell. How mitochondrial dysfunction can lead to health problems Mitochondria are integral to many essential physiological processes in the body. Not only do they produce energy for cells, but they also play a key role in maintaining cellular structures and initiating cell division. Therefore, any disruption of normal mitochondrial function can have far-reaching consequences for overall health and well-being. Maladaptive responses to environmental stressors, such as chemical exposure or radiation, are among the most common causes of mitochondrial dysfunction. These stressors result in damage to mitochondrial DNA and can cause problems with cell division and abnormal growth patterns, which can lead to a range of disorders and chronic diseases. For example, mitochondrial dysfunction has been linked to conditions like Alzheimer's disease and type 2 diabetes, as well as cardiovascular disease and cancer. Therefore, it is important to understand the role that mitochondria play in maintaining healthy functioning bodies and take proactive steps to prevent or reverse damage from maladaptive responses to environmental stressors. Mitochondria and Longevity Mitochondria are specialized organelles found within our cells that perform many critical functions, including generating energy to support cellular processes and maintaining healthy cell function. These organelles are the site of many important chemical reactions, often referred to as oxidative phosphorylation or metabolism. Studies have shown that Proper functioning of these organelles is essential for healthy aging, and may be a key factor in determining how long we live. By promoting mitochondria health and making lifestyle changes that help to promote healthy mitochondria, we can take an important step towards optimizing our longevity potential. This includes eating a nutrient-rich diet with a focus on foods high in antioxidants, managing stress levels through regular exercise and relaxation techniques, and avoiding environmental toxins that can damage mitochondria health. Through such strategies, we can give ourselves the best chance at living a long, full life. Ways to protect your mitochondria and keep them healthy with PQQ PQQ, or pyrroloquinoline quinone, is an important molecule for the functioning of mitochondria in the human body. This compound plays a crucial role in adenosine triphosphate (ATP) synthesis, the fundamental energy currency of biological systems. By driving cellular processes that release energy for metabolic use, PQQ plays a key role in maintaining mitochondrial health and efficiency. Additionally, PQQ has been shown to exhibit powerful antioxidant properties, which help to mitigate the effects of oxidative stress on mitochondria and other critical cells in the body. Overall, PQQ is an essential component of healthy mitochondrial function and a crucial nutrient for energy production and overall metabolic health. D-ribose, the Mitochondria, and Energy D-ribose is a naturally occurring sugar that plays an important role in cellular metabolism and energy production. This nutrient is especially important for cells that rely on a lot of energy, such as those found in the heart and muscles. D-ribose helps these cells to generate adenosine triphosphate, or ATP, which is the main energy currency used by cells to drive chemical reactions. Additionally, research has suggested that d-ribose can help to improve physical endurance and reduce the pain and stiffness associated with exercise, making it an important part of a healthy, active lifestyle. Also, D-ribose is a simple sugar that plays an important role in the structure and function of mitochondria, the powerhouses of the cell. In addition to supplying energy to the cells, mitochondria also help to regulate cell growth and death. D-ribose is essential for the proper function of mitochondria, and it plays a key role in energy production. Studies have shown that D-ribose can help to improve mitochondrial function and reduce fatigue. In addition, D-ribose supplements have been shown to improve exercise performance and increase energy levels. These effects are likely due to the ability of D-ribose to help the body produce more ATP, the energy currency of the cell. For these reasons, D-ribose is an important nutrient for maintaining healthy mitochondria and supporting cellular energy production. Another important nutrient for the mitochondria is CoQ10 The process of producing energy is called oxidative phosphorylation, and it involves the transfer of electrons from nutrients to oxygen. This reaction creates a proton gradient across the mitochondrial membrane, which is used to generate ATP, the energy currency of the cell. Coenzyme Q10 (CoQ10) is an important component of this process. It acts as an electron carrier, shuttling electrons between enzymes in the respiratory chain. It also helps to maintain the proton gradient, allowing the mitochondria to continue generating ATP. Without CoQ10, oxidative phosphorylation would grind to a halt, and cells would quickly run out of energy. Consequently, CoQ10 plays a vital role in energy production and cellular metabolism. The bottom line is that both D-ribose and CoQ10 are important nutrients the body needs to maintain optimal energy levels. If you’re feeling run down, low on energy, or just generally not your best, consider taking a supplement containing these two nutrients. You may be surprised at how much better you feel once you start including them in your diet. What’s stopping you from giving them a try?
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6395) Polyphenols: The Powerful, Health-Boosting Nutrients in Rainbow-Colored Foods
Date:
April 25, 2022 11:54 AM
Polyphenols are a type of nutrient found in a variety of rainbow-colored foods. These nutrients offer a range of health benefits, from boosting your immune system to protecting your heart. Polyphenols are especially beneficial for promoting good health and preventing disease. In this blog post, we'll discuss what polyphenols are, where you can find them, and some of the health benefits they offer. What are polyphenols and what do they do for the body? Polyphenols are a type of micronutrient that are found in plant foods. They're known for their antioxidant properties, meaning they help to protect cells from damage. Polyphenols can also help to reduce inflammation and promote heart health by reducing cholesterol levels and blood pressure. Some research has also shown that polyphenols may help to prevent certain types of cancer. The body needs polyphenols for several different functions, making them an important part of a healthy diet. Most people consume adequate amounts of polyphenols through their diet, but those who don't eat many plant foods may want to consider taking a supplement. Polyphenols and cancer prevention Research has shown that polyphenols may play a role in cancer prevention. One mechanism by which polyphenols may protect against cancer is by inhibiting the growth of cancer cells. Polyphenols may also help to protect DNA from damage, which can lead to the development of cancer. Additionally, polyphenols can induce apoptosis, or cell death, in cancer cells. Some studies have also suggested that polyphenols may help to reduce inflammation, which has been linked to the development of cancer. While further research is needed to better understand the role of polyphenols in cancer prevention, the existing evidence suggests that consuming polyphenol-rich foods may help to reduce the risk of developing cancer. Polyphenols and heart health Polyphenols are known for their antioxidant properties and have been linked to a number of health benefits, including heart health. Some studies have shown that polyphenols may help to reduce the risk of cardiovascular disease by reducing inflammation and improving blood vessel function. Polyphenols may also help to lower blood pressure and cholesterol levels, two key risk factors for heart disease. While more research is needed to confirm these benefits, consuming foods rich in polyphenols is a simple way to support heart health. Good sources of polyphenols include fruits, vegetables, nuts, seeds, and vitamin supplements. Including these foods as part of a healthy diet is a good way to ensure that you're getting adequate levels of this important micronutrient. Polyphenols and brain health While they are sometimes necessary in small quantities for human health, recent research has suggested that they may also have beneficial effects on brain health. One study found that polyphenols may help to improve cognitive function in older adults, while another found that they may help to reduce the risk of dementia. Additionally, polyphenols have also been shown to protect neuronal cells from damage and death. As a result, consuming foods rich in polyphenols may help to protect the brain from age-related decline. The benefits of polyphenols for overall good health
Polyphenols can also help to improve gut health by promoting the growth of healthy bacteria and reducing inflammation. In addition, polyphenols have been shown to boost the immune system and reduce the risk of chronic diseases such as diabetes. Given their wide range of health benefits, it is no surprise that polyphenols are sometimes referred to as the "supernutrient." However, more research is needed to determine the optimal intake of polyphenols for human health. How to get more polyphenols in your diet Polyphenols are a type of micronutrient that has been shown to offer a variety of health benefits. They are found naturally in bright colored fruits and vegetables, but the best way to get a high concentration of polyphenols is through a supplement. If you want to spare your self the calories of consuming large amounts of fruits and vegetables, one can take a supplement like Source of Life Red Lightning, which contains 30 whole foods and super fruits, its packed with antioxidants and polyphenols. Polyphenols have been shown to improve heart health, reduce inflammation, and boost cognitive function. In addition, they are believed to play a role in cancer prevention. While more research is needed to confirm these health benefits, there is no doubt that polyphenols can have a positive impact on overall health. If you are looking for a way to improve your health, consider adding a polyphenol supplement to your diet.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6391) Can choline be used as an alternative treatment for Alzheimer'sdisease?
Date:
April 26, 2019 02:48 PM
While we don't what causes Alzheimer's disease, new research from Arizona State University points to choline as a promising treatment for the condition. When mice consumed large amounts of choline, they showed positive improvements in spatial memory. Furthermore, these positive benefits were evident in their offspring, even though they did not supplement directly with choline. Researchers believe that choline helps to control brain inflammation and neuron death, processes that both contribute to Alzheimer's. Experts recommend that adults take 550 milligrams of choline daily for optimal brain health Key Takeaways: "In other words, choline could help protect against this illness across several generations. It was the first time researchers have been able to show the transgenerational benefits of choline supplementation." Read more: https://www.naturalnews.com/2019-03-11-choline-a-natural-treatment-for-alzheimers-disease.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6195) A diet rich in nuts like almonds is found to drastically improvecolon cancer survival
Date:
April 23, 2019 03:10 PM
The antioxidant properties of just 100 grams of walnuts astoundingly has the antioxidant properties of over one-hundred oranges! Consuming walnuts, pecans, and almonds routinely can help decrease your risk of colorectal cancer due to these antioxidants that are naturally present within their makeup. Even those who had advanced stages of colorectal cancer were shown to be able to halt spreading through an in increase of healthy eating and nuts in their diet paired with regular physical activity. Key Takeaways: "Almonds have immense health benefits and are ideal in improving bowel cancer." Read more: https://www.naturalnews.com/2019-03-06-nuts-like-almonds-drastically-improve-colon-cancer-survival.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6164) Eating fried food just twice per week increases your chance of early death
Date:
August 17, 2018 09:53 AM
Nature News puts out an article on a possible link between routinely eating deep fried foods and premature deaths. One of the possible causes of an early death is acrylamide, which is present in some foods, one of which is deep fried potatoes. To cut down on risks, Nature News recommends cutting back on eating deep fried foods more than once a week(preferably even less often) and finding healthier substitutes. Substitutes could include vegetables or oven baked sweet potato fries. Key Takeaways: "To stay healthy and lower your risk of premature death, limit your intake of fried foods like French fries and potato chips." Read more: https://www.naturalnews.com/2018-08-16-eating-fried-food-just-twice-per-week-increases-your-chance-of-early-death.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5710) New non-invasive eye test can detect Alzheimer's 20 years before symptoms start
Date:
August 22, 2017 07:14 PM
Researchers at hospital in Los Angeles have published a report claiming they have developed an eye test that can detect Alzheimer's disease well in advance - twenty years - before actual symptoms show up. Traditional methods of diagnosing this disease are to perform look at the patient's brain after death, or to perform a PET scan. The report just published claims it can detect the disease by scanning a patient's retina for plaque. The test is non invasive. A link to the journal where the report appeared is included in the article. Read more: New non-invasive eye test can detect Alzheimer's 20 years before symptoms start
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5163) Cannabinoids can successfully kill leukemia cells, reveals groundbreaking new study
Date:
June 21, 2017 12:14 PM
Leukemia, which is prevalent in both children and adults, is a bone marrow cancer that results in an abnormal production of white blood cells.As for leukemia treatment, now it’s simply a matter of figuring out the most optimal combinations for greater effectiveness. Cannabis has long been known as having the ability to kill cancer, but the new revelation regarding leukemia is important because the disease is a cancer of bone marrow and other blood forming organs. Key Takeaways: "The study revealed that the cannabiniod varieties cannabidiol and tetrahydrocannabinol (THC) eliminated leukemia cells when used alone." Read more: http://www.naturalnews.com/2017-06-20-cannabinoids-can-successfully-kill-leukemia-cells-reveals-groundbreaking-new-study.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4862) Cannabis phytochemicals found to be effective in destroying leukemia cells
Date:
June 14, 2017 07:14 PM
A recent study shows that cannabinoids fight against leukemia cancer cells if administered in the correct order. When the cannabinoids were given to patients after they received chemotherapy it showed cancer cell death, but it didn't show nearly as effective when given before chemotherapy. When cannabinoids are used in conjunction with chemotherapy it can diminish the unfavorable side effects of chemotherapy significantly. There is still more to be learned, but so far the results look promising. Read more: Cannabis phytochemicals found to be effective in destroying leukemia cells
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4833) CONFIRMED: Omega-3s boost blood flow to regions of the brain responsible for learning and memory
Date:
June 02, 2017 12:14 PM
A new study finds an increase in blood flowing to your brain, and it may help to prevent cognitive disorders such as Alzheimer's. Alzheimer's disease is a leading cause of death, causing a downward deterioration of a person ability to live independently as the symptoms become worse. The study shows correlation between omega-3 concentrations in the brain with a lower incidence of brain disease, called neurocognitive disorders. The omega-3 is found to be the cause of increased blood flow to the brain, resulting in a decreased probability of neural degradation. Key Takeaways: "This study opens the door to the possibility that relatively simple dietary changes could favorably impact cognitive function." Read more: http://www.naturalnews.com/2017-05-25-confirmed-omega-3s-boost-blood-flow-to-regions-of-the-brain-responsible-for-learning-and-memory.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4754) Can a blood test determine whether you'll be alive in 5 years?
Date:
December 11, 2016 08:59 AM
If you could find out your approximate age of death, would you want to do so? Soon to be available in the U.K , the test measures the length of telomeres, a DNA structure which controls the longevity of dividing cells. The shorter the telomere, the faster you are aging. A very specific blood test can determine telomere length and, based on the length can use an algorithm to assess longevity based on current lifestyle. Key Takeaways: "There is growing evidence that a simple blood test could determine your risk of dying in five years." Reference:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3619) MSG: Here is why you should stay far away from it.
Date:
September 20, 2016 03:15 PM
MSG is a neurotransmitter that stimulates nerves, which makes food that would normally be bland taste great. Because MSG is often used to compensate for low-sodium or low-fat contents, many food manufacturers try to downplay its toxicity in order to promote their products as healthy. As a result, people who believe they are buying healthy foods are actually putting their health at risk by consuming large amounts of MSG.
The following are the health risks of MSG:
MSG is widely used in the food industry, which makes finding MSG-free foods a challenge. It is often hidden on ingredient lists under different names to mislead consumers.
If you are experiencing inflammation issues, take Curcumin to eliminate all forms of inflammation.
Reference: //www.mayoclinic.org
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3301) Benefits of Extended Release Guggulipid
Date:
January 03, 2013 04:10 PM
Guggul is one of the holistic ancient herbal extracts derived from the Commiphora wightii plant that had been predominant in India although some parts of northern Africa and Asia still had some traces of the same. Over the years, Guggul resin gum derived from the plant has been used to promote a healthy living, and has a good number of recent scientific research findings to back it up. Some of the health benefits associated with the use of Guggulipids supplements (also known as the Guggulsterone Supplements) include lowering of Low Density Lipoproteins (Bad Cholesterol), reducing inflammation, and significantly lowering the risk of suffering from cardiovascular diseases, tumors and cancers. Research: Extensive scientific research shows that Guggulipids play an important role in inhibition of its synthesis in the liver and its hydrolysis into bile salts. It also acts on the thyroid gland which in turn controls the Basal Metabolic Rate that directly relates to the rate of cholesterol catabolism in the body. Additionally, a cascade of reactions in the liver during the process of cholesterol hydrolysis down-regulates the uptake of cholesterol in the gut which ensures that the body is at a healthy blood cholesterol level. Anti-Inflammatory: The anti-inflammatory, anti-tumor and anti-cancer effects are highly associated with the stimulation of the liver to release C-Reactive Protein. Even though the CRP protein is primarily produced by the body in response to inflammation and cell death, presence of the CRP in the blood stream prior to an acute inflammation or cell death plays an important role in toning down inflammatory conditions such as rheumatoid inflammation as well as killing abnormal cells before they develop into tumors and cancerous cells. However, Guggulsterones are rapidly regenerated in the body in the same rate that other steroid hormones are degenerated which makes the use of extended release Guggulipid supplements very essential. This makes it possible to have the body under constant supply of the component for optimal guggulsterone health benefits.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2801) The health benefits of artichoke leaves
Date:
December 07, 2012 01:12 PM
Artichoke has been a very popular vegetable since ancient times due to its great taste and abundant health benefits. Although most people prefer eating its heart, it's actually the artichoke leaves that contain most the ingredients that are beneficial to the body. The following is an overview of the health benefits of artichoke leaves. Contain powerful antioxidants Artichoke leaves and flower heads have one of the highest antioxidant capacity reported for vegetables. Its powerful antioxidants can help you to detoxify your body, as well as avoid problems that are associated with free radicals in the body, including weak immune system, aging skin, decreased energy and weight gain. Lower cholesterol The ingredients found in the artichoke leaves extract have been found to lower levels of bad cholesterol (LDL) in the body. They achieve this by inhibiting the enzyme HMG- CoA reductase, which is responsible for cholesterol production. This reduces the risk of coronary heart disease, arteriosis and other cardiovascular issues. Help to treat and prevent cancer Artichoke leaves extract contains substances that are known to induce apoptosis or “cell death,” which inhibits cell proliferation in different forms of cancer, such as breast cancer, prostate cancer and leukemia. Increase bile flow The pulp of artichoke leaves is rich in Cynarin - a chemical substance that is known to increase bile flow. Healthy bile flow helps to avoid a variety of health problems such as Candida, parasites, constipation, gallstones, high cholesterol, irritable bowel syndrome, diabetes and insulin issues. Improve digestion Artichoke leaves extract contains diuretic effects and has been shown to aid digestion. It improves bile flow, which in turn stimulates peristalsis, required for better digestion. This keeps digestive problems such as constipation away. Strengthen liver and gall bladder function As a natural diuretic, artichoke leaves extract boosts both liver and gall bladder functions. This is actually the reason why they are considered to be an effective hangover treatment. Rich in fiber Artichoke leaves are high in fiber, and they can be very handy when you are trying to lose weight, or fight digestive problems.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2745) What Are The Health Benefits Of Taking Kelp?
Date:
June 25, 2012 08:24 AM
Common people came to know about kelp only after the nuclear war, which demolished two beautiful cities of Japan. How kelp is related to nuclear war? How it helped people after the nuclear bomb explosion? The Co-relation between Kelp and the Nuclear War After the nuclear explosion the radioactive iodine spread through the air. People, who were completely unaffected by the nuclear explosion, fell sick by absorbing the radioactive iodine. The medical scientists come up with a fantastic idea to save people from the fatal iodine then. They advised people to take kelp pills. Kelp is highly rich in iodine. So, if a person is taking kelp pills, then he or she would require no more iodine, hence their would be no absorption. This miraculous idea saved millions of people from the harmful radioactive iodine after the Second World War. Now, whenever there is a need of iodine, physicians recommend to go for kelp. You would find kelp pills in the medicine boxes of most of homes. Other Health Benefits of Kelp Apart from the radiation poisoning, kelp pills could help a person's body in many other ways. Iodine is required for the normal functioning of the thyroid gland. Kelp pills could be used in case of thyroid malfunction. The iodine content of kelp could be used for female hormone regulation. The immune system requires iodine to function properly. If the immune system of any person is getting weaker or not functioning as it should be due to low iodine concentration in body, then the patient could avert the situation by taking iodine-rich kelp pills. Kelp is probably the only natural product, which helps a person to fight against the most fatal disease, cancer. Fucoidan, which has the potency to induce cell death in cancerous cells, is found only in kelp. Apart from the ability to start cell death, Fucoidan possess anti-inflammatory properties also, may reduce pain. In fact, Fucoidan is considered as one of the strongest natural anti-inflammatory agents. Kelp is not only rich in iodine but it contains iron too. If any person is suffering from iron deficiency, then he should go for kelp instead of anything else, as it is a natural source of iron. Pregnant women could take the help of kelp pills to meet the extra requirement of iron in their bodies. One could reduce the danger of suffering from estrogen cancer by regular taking of kelp, either in diet or by in taking kelp pills. Generally, the diet of Japanese people is rich in diet. If you look at the estrogen related cancer cases in Japan, then you would find it is one of the lowest in the world. Kelp has pain killing properties. Kelp is used specially in case of endometriosis. Any woman suffering from endometriosis could get rid of pain by taking one 700 mg capsule of kelp. Do you have kelp pills in your medicine box? If yes, it is well and good. If you are yet to keep kelp along with you, then don't waste any time. Go ahead and keep kelp pills in your home.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2658) Can Lycopene Help with Prostate Problems
Date:
May 09, 2011 11:14 AM
Lycopene and The Prostate.Lycopene is an organic compound often associated with tomatoes. It is almost always touted to prevent prostate cancer, though the scientific community has not come to a conclusion yet. Scientists are nevertheless positive that it is good for the prostate, for it displays antiproliferative effects on prostate cells. Laboratory studies are very promising as it appears to inhibitory effect on tumor growth. Prostate health has long been tied to consumptions of foods rich in lycopene. It is a carotenoid that is bright red in color, and as such can easily be obtained from brightly colored plant products, such as watermelon, papaya, pink guava, and apricots in addition to tomatoes. Like other carotenoids, it displays antioxidant properties. In fact, it is the most efficient scavenger of singlet oxygen of all antioxidants that are classified as carotenoids. Reverses Oxidative Damage There have been numerous studies on lycopene in the past few decades, and many of them have noted its antioxidant potential. It has become common knowledge that lycopene is good for the prostate, but not all people know that the prostate gland is its primary storage in the human body. Indeed lycopene interferes with the health of cells and tissues that make up the prostate gland. One study that tracked down malignant prostate tissues prior to scheduled surgical removal studied the effects of regular intake of lycopene. It was documented and published that lycopene concentrations in the prostate doubled and the oxidative damage to DNA in prostate tissues decreased, suggesting a dose-related efficiency in the prevention of cellular damage brought on by free radicals and other reactive oxygen species. Induces Apoptotic death High consumptions of lycopene appear to directly counteract with cancer cells and tumor growth, not only in the prostate gland, but also in the lungs, breasts, ovaries, stomach, and cervix. It has also been tied to other disorders of the prostate, such as prostatitis and benign prostatic hyperplasia, or BPH. It has been noted to slow down cell proliferation that leads to the enlargement of the prostate. More imporatantly, lycopene seems capable of inducing the cellular process called apoptosis, or programmed cell death, in prostate tissues, most notably in carcinoma regions. This is also evidenced by a significant decrease in prostate-specific antigen in the blood, the reason why lycopene has gained the attention of researchers for prostate health, spurring a number of studies in recent years. Maintains Prostate Health Lycopene levels in the human body are largely dependent on dietary intake. As a general rule, the higher the intake of lycopene is, the healthier the prostate becomes. First, it neutralizes reactive oxygen species such as singlet oxygen and free radicals. It also inhibits the multiplication of prostate cells, effectively preventing benign prostatic hyperplasia, which is believed to afflict up to 80 percent of the male population. For those suffering from prostate enlargement, it slows the progression of the disease. If you are, 40 years old or more you should consider taking lycopene as a preventative daily!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2291) Natural Anxiety Remedies
Date:
November 11, 2010 05:44 PM
Anxiety disorder is a much more common problem than what was once thought. It often affects people in their teenage years through middle age and later. Anxiety disorder appears to affect twice as many women as men. However, there may not be that wide of a disparity between the sexes. Psychologists simply believe that men are far less prone to report or even acknowledge that they have a problem of this nature. Anxiety disorders can either be acute or chronic. Acute anxiety disorder manifests itself in episodes that are commonly known as panic attacks. A panic attack occurs when the body’s natural “fight or flight” reaction occurs at the wrong time. This is a complex response in which the body prepares itself to deal with an emergency situation. Stress can often cause the body to produce more adrenal hormones, especially adrenaline. The increased production of adrenaline causes the body to step up its metabolism of proteins, fats, and carbohydrates to quickly produce energy for the body to use. Additionally, the muscles tense up and the heartbeat and breathing become more rapid. When faced with an assault, accident, or a natural disaster, this type of reaction is perfectly normal. However, the symptoms that are caused by the surge in adrenaline can be distressing and frightening when they occur at the wrong time. A person having a panic attack is often overwhelmed by a sense of impending disaster or death, which makes it impossible to think clearly. Other feelings that can accompany a panic attack include shortness of breath, a smothering, claustrophobic sensation, heart palpitations, chest pain, dizziness, hot flashes or chills, trembling, numbness or tingling sensations in the extremities, sweating, nausea, a feeling of unreality, and a distorted perception of the passage of time. This disorder can eventually have other cumulative effects such as generalized aches and pains, muscular twitching and stiffness, depression, insomnia, nightmares and early waking, decreased libido, and abnormal feelings of tension with an accompanying inability to relax. Panic attacks are usually abrupt and intense, occurring at any time of the day or night, and lasting from several seconds up to half an hour. To the panic sufferer, it often feels as though they are much longer. A person having a panic attack sometimes believes that he or she is experiencing a heart attack or stroke. The attacks themselves are very unpredictable, with some people experiencing one every few weeks, and others having several each day. Panic attacks are often triggered by stress or certain emotions, but they can also be a response to certain foods, drugs, or illness. Many people with acute anxiety disorder become afraid of being alone and visiting public places because they fear having a panic attack. This only adds to the level of anxiety and leads to abnormally restricted lives. Psychologists often believe that at least in some cases, panic attacks are self-induced, meaning that the fear of the panic attack is the very thing that brings it on. The following nutrients are recommended for dealing with anxiety disorders: calcium, magnesium, B1, B12, multivitamin and mineral complex, SAMe, vitamin B, vitamin C, vitamin E, zinc, chromium picolinate, DLPA, L-glutamine, coenzyme A, essential fatty acids, GABA, melatonin, bilberry, ginkgo biloba, milk thistle, catnip, chamomile, cramp bark, kava kava, hops, linden flower, motherwort, passionflower, skullcap, fennel, lemon balm, willow bark, feverfew, St. John’s wort, skullcap, valerian root, and mandarin oil. Natural vitamins and herbs can be found at VitaNet ®, LLC Vitamin Store.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2197) Glutathion, Antioxidants, And The Body
Date:
July 14, 2010 02:41 PM
Glutathione is a simple protein that consists of three amino acids. These amino acids include glutamic acid, cysteine, and glycine. Due to the chemical nature of sulphur-containing cysteine, glutathione is able to effortlessly donate electrons. This ability is the reason why it has powerful antioxidant properties. Intracellular glutathione status is a sensitive indicator of cellular health and of the cell’s ability to resist toxic challenges. Glutathione is an important water-phase antioxidant that is an essential component in the glutathione peroxidase system. Glutathione peroxidase enzymes are crucial for detoxifying peroxides including hydrogen peroxide, which is generated within cellular membranes and lipid-dense areas of the cell, especially the mitochondrial membrane. Severe glutathione depletion often leads to cell death, while experimental glutathione depletion has been found to induce cellular apoptosis. A cellular level of glutathione depletion seems to cause extensive damage to the mitochondria. Depletion of mitochondrial glutathione may, in fact, be the ultimate factor that determines a cell’s vulnerability to oxidative(free radical) attack. The mitochondria is the most crucial place for glutathione presence, as the cascade of oxidation-reduction reactions complete the final steps in respiration take place here. Throughout this process, which is called oxidative phophorylation, electrons invariably escape and react with the ambient oxygen in order to generate toxic free radicals. It has been estimated that 2% to 5% of the electrons that enter the mitochondria are converted into reactive oxygen species that generate considerable oxidative stress for the cell. These free radicals cause an immediate threat to other cellular components, such as the DNA, enzymes, structural proteins, and lipids. The cumulative damage that is caused by oxygen and other free radical species is now determined to be the principal contributor to the degenerative disease process and the progressive loss of organ function that is commonly recognized as aging. Because of this, the cell is constantly challenged to destroy these free radicals before they can inflict any lasting damage. Minimizing oxidative attacks may actually be the ultimate challenge of being alive. Because of this, the reducing power of glutathione is of huge important to the cell. Glutathione is important for helping to regenerate other antioxidants that are depleted from their constant work to fight off free radical challenges. Regeneration that is glutathione-induced may be the mechanism that is actually used by the cell in order to conserve lipid-phase antioxidants, vitamin A, vitamin E, and the carotenoids. It has been confirmed by recent investigations that dietary vitamin C can actually protect us against tissue damage that results from glutathione depletion. Additionally, supplementation with glutathione or its precursors can also quickly replenish any vitamin C deficiencies. Because of this, glutathione and ascorbic acid, both of which are pre-eminent cellular antioxidants, are tightly linked, as glutathione can conserve vitamin C and vitamin C can conserve glutathione. When they are both present, these two antioxidants protect the entire spectrum of biomolecules that are found within the cell, as well as facilitate the cell’s best performance. It has been said that the glutathione status of a cell may be the most accurate single indicator of the health of the cell. This means that as glutathione levels go, the health of the cell will go as well. Glutathione is available in capsule or tablet form at your local or internet health food store. Always choose name brands to ensure quality and purity of the glutathione supplement you choose to purchase for consumption.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2171) Yeast Cleanse
Date:
January 26, 2009 01:26 PM
When the immune system is compromised or nutrition is below standards, yeast organisms, including Candida Albicans, can invade the body and cause a whole variety of miserable symptoms. A yeast infection is a generally misunderstood condition which thrives in warm-blooded animals. With 900 species of yeast existing, the candida variety is the one that we have to deal with. Candida is similar to the type of yeast that is used to make bread. It is an oval-shaped microorganism that can reproduce rapidly by budding. Candida is unable to thrive on its own, with almost everyone having intestinal candida colonies. It is actually one of many organisms that thrive in our intestinal flora. Normally, yeasts live in harmony with us thanks to a delicate balance of bacterial types. However, a yeast infection results when a certain set of physiological circumstances encourage the growth of more yeast. A lot of people experience a sensitivity to yeast in specific mucous membranes where the climate is moist and favorable such as the mouth and gastrointestinal tract. It is unknown as to why exactly we have yeast in our bodies. After death, yeast organisms are responsible for initiating the work it takes to decompose our remains. When yeast organisms are able to flourish, a lot of systemic reactions take place, with some seeming unrelated, but together, making us feel downright lousy. The presence of yeast infections often suggests that our overall health may be somewhat weakened or our immune system may be compromised. The human body possesses a variety of microorganisms that have to compete for nourishment. A health and properly maintained system causes these life forms to live in a harmonious balance with each other. Our skin and intestinal tracts provide the perfect home for these bacteria and fungi, as they release certain toxins and provide population control for each other. This biological balance can be easily offset when a number of factors exist. The development of yeast infection is often the first sign that we are not in overall good health. Candida releases powerful poisons as it multiplies which circulate in the bloodstream and cause a variety of symptoms and disorders. The organisms can cause chemical reactions in the body and interfere with the body’s ability to destroy them. It can also produce a type of false estrogen that signals enough estrogen production, causing estrogen production to be inhibited. Candida Albicans is a very serious disease if it is allowed to thrive and is left untreated. Now as common as premenstrual syndrome, the two diseases even seem to go hand-in-hand, producing similar symptoms. Candida can invade a variety of body tissues and cause inflammation at the site. It typically attacks the mouth, gastrointestinal tract, urinary tract, prostate gland, skin, and finger or toenails. The majority of the time we are totally unaware that yeast colonies occupy our bodies. However, if we come down with a yeast infection we can be sure that there is something else going on that will encourage uncontrolled yeast production. Three out of every four adult females will experience at least one episode of Candida, with most of these suffering from a recurrent infection.
Several physiological conditions which make us susceptible to a yeast infection include faulty nutrition, antibiotic therapy, a compromised immune system, and hormonal changes of pregnancy and PMS. Fortunately, natural alternative yeast cleanse formulas are available to help reduce the occurrence of bad yeast all of which are available at your local or internet health food store.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1961) Pretend Medicine: let’s play doctor!
Date:
September 19, 2006 05:44 PM
(NewsTarget) Conventional medicine, as practiced today, is actually pretend medicine. Doctors and drug companies pretend to make patients healthier by giving them drugs. The FDA pretends to protect the safety of the public. Medical journals pretend to print only rigorous, scientifically-sound research papers. Drug companies pretend to care about the lives and health of patients. Non-profit disease front groups pretend to be searching for the cure while, in reality, most of them are only searching for more ways to recruit patients into conventional medicine treatments like drugs, surgery, chemotherapy and radiation. How do we know it’s all pretend? Aside from the junk science, corruption fraud, collusion, conflicts of interest and intellectual dishonesty that characterizes modern medicine, there’s one more all-important thing to consider. The results. If modern medicine really worked, and wasn’t just pretend, wouldn’t we be the healthiest population in the world? (Instead of being 38th?) Seriously. We Americans pay more for health care, per capita, than any nation in the world. We take more drugs, undergo more surgical procedures, and log more hospital visits than anyone else. If the drugs-and-surgery approach to medicine actually produced healthy human beings, shouldn’t we be the healthiest people on the planet? But look around. We are the most diseased people on the planet. We have more disease, disorders and illness than any population that has ever been observed in the history of human civilization (Aside from plagues and the like). The reason is because the medicine being practiced today is pretend medicine. As all of this unfolds, of course, the mainstream media will pretend to offer objective reporting on the health care crisis, relying on journalists who pretend to actually know something about health. Conventional medicine exists in a fantasy. While cancer groups, researchers and drug companies promise enhanced health and quality of life, the reality is far different: accelerating chronic disease, skyrocketing health care costs that are putting U.S. companies like General Motors flat out of business, and hundreds of thousands of Americans being literally killed by medication side effects – an atrocity that the FDA still hasn’t seemed to notice. Conventional medicine is actually the leading cause of death in the United States, killing over 750,000 Americans each year (drug death, hospital deaths, latrogenic deaths combined, source: death by medicine). That’s the reality of the situation. Maybe its time we all stopped pretending. Perhaps its time that conventional medicine stopped playing doctor and started helping patients heal with natural, safe and effective treatments that work for real. Because once Americans are killed by prescription drugs, we cant merely pretend to bring them back.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1385) Review of Omega-3 Studies shows Heart Health Connection
Date:
August 03, 2006 02:53 PM
Review of Omega-3 Studies shows Heart Health Connection… A recent systematic review of studies on omega-3s from oily fish and supplements showed that the fatty acid may reduce the risk of cardiac and sudden death, and potentially stroke, Published in the American Journal of Clinical Nutrition (2006, Vol.84: 5-17), the review only considered studies that lasted longer than one year and that reported or estimated omega-3 intakes and cardiovascular (CVD) outcomes. Most trials reported that fish oil significantly reduced all-cause mortality, myocardial infraction, cardiac and sudden death, or stroke. Primary prevention of cardiovascular disease was reported in one randomized controlled trial, in 25 prospective cohort studies, and in seven case-control studies. The effects on stroke were inconsistent. Evidence suggests that increased consumption of omega-3s from fish or fish-oil supplements reduces the rates of all-cause mortality, cardiac and sudden death, and possibly stroke.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1338) Benefits of Acetyl-L-Carnitine
Date:
February 12, 2006 01:55 PM
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1216) B Vitamins Avert Stroke, Coronary Disease, Death
Date:
January 25, 2006 04:30 PM
B Vitamins Avert Stroke, Coronary Disease, death London, Ontario--Taking B Vitamins may lower homocysteine levels, thereby reducing the risk of ischemic stroke, coronary disease and death, according to an efficacy analysis of the Vitamin Intervention for Stroke Prevention trial (VISP). Published in Stroke (36, 11:2404-09, 2005) (//stroke.ahajournals.org), the analysis outlined researchers’ criticisms of VISP: Participants in VISP may have been administered folate-fortified grain products, the low-dose arm of the study may have been given the recommended daily intake for b12, low-b12 patients in both study arms may have been treated with parenteral b12, test subjects with malabsorption may have been administered an excessively low dose of b12, study participants may have been taking vitamins outside of the study, and patients with significant renal impairment may have failed to response to vitamin therapy. In the efficacy analysis of VISP, researchers excluded patients with very low and very high b12 levels at baseline (less than 250 pmol/L and greater than 637 pmol/L, respectively, representing the 25th and 95th percentiles), in order to eliminate test subjects with b12 malabsorption, ongoing b12 supplementation outside the study and significant renal impairment. The resulting subgroup was comprised of 2,155 patients, 37 percent female, with a mean age of 66 plus or minus 10.7 years. There was a 21 percent reduction in ischemic stroke, coronary disease and death in the high-b12 dose group compared with the low-b12 does group. Kaplan-Meier survival analysis of the four groups indicated patients with b12 levels at the median or higher at baseline who were randomized to the high-b12 dose showed the best overall outcome, whereas those with baseline b12 levels lower than the median who were assigned the low-b12 dose had the worst general outcome. In the era of folate fortification, b12 plays a key role in vitamin therapy for total homocysteine may be needed for some patients.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1195) Industry Groups Warn against Marketing Avian Flue Remedies.
Date:
January 17, 2006 04:52 PM
Industry Groups Warn against Marketing Avian Flue Remedies. Washington—Jointly, the Council for Responsible Nutrition (CRN), American Herbal Products Association (AHPA) and National Nutritional foods association (NNFA) issued a statement in November reaffirming and calling for responsible use and marketing of dietary supplements, and encouraged consumers and retailers to avoid supplements purporting to prevent or treat the avian flu. “The dietary supplement industry is keenly aware of public concern regarding avian flu and of the desire of the public to protect itself against this recent health epidemic, which can cause serious illness and, ultimately, death,” the statement read. “We do not believe any dietary supplements have been specifically shown to prevent or treat avian flu.” The trade coalition futher issued the following unified guidance for marketers, retailers and consumers: “Millions of Americans value dietary supplements because they can enhance general immune function and disease resistance,” they noted. “however, therapies for prevention or treatment of avian flu should only be recommended by a qualified health care professionals or public health authorities.”
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1187) The Free Radical Theory
Date:
December 14, 2005 12:11 PM
The popular theory has been the subject of a great deal of research. Developed by Denham Harman, M.D., Ph.D., at the University of Nebraska in 1956, the free radical theory proposes that unstable molecules known as free radicals are responsible for inflicting extensive cellular damage, which causes cell death and dysfunction and eventually, disease. The most common type of free radicals are oxygen derived, and free radical damage is often referred to as oxidation. Environmental sources of free radicals include radiation (I.E., sun exposure, X-rays), ozone and nitrous oxide, heavy metals (i.e., mercury, cadmium, lead), smoke, alcohol, saturated fat, and other chemicals and pollutants. The body itself generates free radicals in performing essential bodily functions including energy production and immune activities. Fortunately, the body also has the ability to create antioxidants to neutralize the free radicals and prevent extensive cellular damage. When free radicals are not neutralized by antioxidants, they inflict large-scale cellular damage which can cascade and lead to age-related degenerative diseases such as osteoarthritis, osteoporosis and age –relaged macular degeneration. For example, free radical damage to joint cells may cause the cartilage to become rough or break down, and can lead to the development of osteoarthritis. Antioxidants are needed to comb at free radicals and prevent this cellular damage. “Oxidative stress can lead to DNA mutations, cell death, and disease, all of which contribute to aging,” said Gerald R. Cysewski, president and chief executive officer (CEO) at Cyanotech corp. “Antioxidants are produced naturally by the body to combat oxidative stress by neutralizing free radicals. Increasing the amount of antioxidants in one’s system by consumption of supplements can provide further protection from the damaging effects of free radicals.” Because the body is continually assaulted by free radicals, antioxidant supplementation is often necessary. “by taking certain nutrients that our bodies stop producing over time, supplements help us to maintain a youthful look and health, which in turn enhances the quality of life,” Alkayali said. “Furthermore, supplements can help decrease oxidative stress that may otherwise accompany age-related illness and disease.” Many Substances are known antioxidants including certain enzymes, vitamins, phytochemicals and minerals, and include Vitamin C, Vitamin E, alpha-lipoic acid, coenzyme Q10 (CoQ10), Carotenoids, Selenium, superoxide dismutase, melatonin, quercetin, catechins, and zinc. Consuming a diet high in plant sources of powerful antioxidants is an important step to deter ageing, because nutrients from foods are often highly bioavailable and can act synergistically to increase their health benefits. Garlic contains several antioxidant phytochemicals and minerals including allicin, beta-carotene, quercetin, selenium and zinc, and may have a protective effect against stomach and colorectal cancers. Catechins are potent antioxidants flavonoids, with the best known source being green tea; they include gallocatechin (GC), epigallocatechin (EGC), epicatechin (EC) and epigallocatechin gallate (EGCG). These antioxidants are being studied for their powerful abilities to combat free radical damage. In particular, EGCG has been researched for its reported protection against certain cancers and Alzheimer’s disease. Green Foods such as seaweed, sea vegetables, young grain grasses and shoots, broccoli, cabbage and other green leafy vegetables pack a nutritional punch due to their concentratged amounts of antioxidant carotenoids, vitamins and the enzyme superoxide dismutase (SOD). SOD is produced by the body and neutralizes free radicals known as superoxide radicals, which cause damaging fat oxidation. GliSODin is a patented form of SOD derived from cantaloupe and bound to a wheat protein for superior bioavailability. “GliSODin promotes the body’s production of its own endogenous antioxidants, including SOD, catalase and glutathione peroxidase, in virtually every cell,” said Eric Anderson, brand manager at P.L. Thomas. “This activation of the cellular antioxidant defenses across the whole body creates a state of alertness against any shock of oxidative stress, including sun rays, to which our body may be exposed.” Pomegranates contain two powerful antioxidants—ellagic acid, derived from fruit’s seeds, and punicaligans, found in the juice. “Research has shown that the juice from the pomegranate, rich in polyphenols, reduces oxidative stress by helping to produce enzymes to fight free radicals,” Alkayali said. NeoCell Corp. manufactures of ellagic-acid based Pomegranate Power, while P.L. Thomas supplies POM40p, a kosher-free pomegranate juice extract standardized to 40-precent punicocides, polyphenols belong to the punicalagin family. Consumer demand is on the rise for products that address degenerative health conditions, including supplements that support function of the bones, joints, eyes. According to a June 2005 report by the freedonia group, “Bone and joint care products will continue to dominate the health maintenance segment, spurred by a growing customer base and a plethora of new and improved products expected to soon enter the marketplace.” The report also projected rapid gains for vision care. “Demand for vision care products will be propelled by aging baby boomers who are becoming aware of debilitating eye conditions and seeking both preventive measures and ameliorative treatments.” Dietary Supplements can help prevent and ease symptoms of age-related diseases affecting the joints, bones and eyes, including osteoarthritis, osteoporosis and age-related macular degeneration (AMD).
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1013)
Date:
November 11, 2005 09:32 AM
Benefits of Omega-3 Fatty Acids
Cardiovascular Disease: Randomized clinical trials are adding to the evidence that omega-3s are beneficial in cardiovascular disease, especially from secondary prevention of myocardial infraction. One of the earliest randomized clinical trials was the diet and reinfraction trial (DART). This trial was designed to examine the effects of dietary intervention in the prevention of secondary myocardial infraction. The subjects advised to increase their intake of oily fish had a 29% reduction in 2-year all-cause mortality. This ovservation lead to the hypothesis that omega-3 fatty acids might protect the myocardium against acute ischemic stress. A post hoc analysis of patients receiving fish oil supplements (900mg/day of EPA and DHA) suggested that the protective effect was attributed to omega-3 fatty acids. Another randomized placebo-controlled trial of patients admitted to the hospital with suspected acute myocardial infraction showed that supplementation with 1.8 g of omega-3 (EPA and DHA) for on year decreased total cardiac events by 29%. Both total cardiac death and nonfatal myocardial infractions were also reduced by 48%. The largest randomized clinical trial to test the efficacy of omega-3 fatty acids for secondary prevention of cardiovascular disease is the GISSI-prevention study. From 1993 to 1995, 11,324 patients surviving myocardial infraction were randomly assigned either vitamin E (300mg daily, as synthetic-a-tocopherol), omega-3 fatty acids (1 g daily, standardized to 850 mg EPA and DHA), both or none. Compared with the control group, patients taking the fish oil showed a 15% reduction in the primary end point of death, nonfatal myocardial infraction, and nonfatal stroke. Patients supplementing with vitamin E online showed no benefit.
With this mounting data, the American Heart Association (AHA) recommends eathing at least two servings of fish per week (particularly fatty fish). The FDA has also announced a qualified health claim linking a reduced risk of coronary heart disease with the long-chain omega-3 polyunsaturated fatty acids.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=930) CLA and Body Fat
Date:
June 22, 2005 09:50 PM
CLA and Body Fat Of all the health concerns facing Americans today, few are as important and daunting as weight loss and body fat. In the 1980s, Americans gained an average of eight pounds each. That’s on the order of 1 million tons of flab—2 billion total American pounds.45 So large is the current girth that as many as two in three Americans could be termed overweight.46 Being overweight and having excess fat increases the risk of heart disease, some forms of cancer and diabetes. That collection of health challenges would be difficult enough, but being overweight has many problems that accompany it, including battles with self-esteem. Let’s give a historical example of this story. The emotional power of being perceived as too fat is caught with pathos in the life of former U.S. President William Howard Taft. Taft, who is the only man to serve as both president and as chief justice of the Supreme Court, was noted for his honesty and his integrity. The nation mourned his death, but much of his internal story focused on his battle with weight. One editorial cartoonist showed the island of Cuba tipping under his girth. Once, when he visited Japan, an entire village worked together to pull his rickshaw up a hill. When he married, his personal esteem showed when he told his wife that “I shall worry you so much with my appetite that you must gain strength to meet the trial.” Taft refused to be seen on a horse because of how awkward he looked. At one point, he lost 75 pounds, but, like so many others, ended up gaining that amount back , and more, during the next 10 years. He died of athero s c l e rosis, something associated with being ove rwe i g h t .4 7 The tragedy of Taft is that, like so many suffering with weight trouble, he seemed to let it damage his self w o rth, when he was a great asset to his nation and to others. History and culture put into us that being overweight means lacking in self-control and being a glutton, when in reality this isn’t true. So many more factors are involved. Each person has a different metabolism. Certain nutrients can meet different needs, and a lack of those nutrients can lead to fat retention. CLA may be one of those nutrients, one of those factors in our diets that can change our shapes and that have nothing to do with self-control, just nutritional luck and knowledge. In a study of rats, 28 days after beginning the study, body fat in those that ate CLA was 58 percent less than in those who didn’t consume any (10.13 percent body fat versus 4.34 percent body fat, a highly significant difference). Also, the percent of muscle was about one percent more in animals that ate CLA. The weights of both sets of animals were about the same.48 (Muscle weighs more than fat. This can mean that you won’t necessarily lose weight with CLA, but would gain muscle mass, which is tighter and more shapely.) The research in this area is slightly newer, but it has been reproduced in studies on other animals.49 That more than one kind of animal has shown that body fat is lower with supplements of CLA indicates that it will likely benefit humans as well. In July 1997, preliminary results of one of the first human studies involving CLA showed promising, preliminary results. For three months in 1997, 20 volunteers participated in a study, daily consuming an amount of slightly more than one gram of CLA at breakfast lunch and dinner. Three months later, their weights and body-fat percents were measured. Half of the group took a placebo. The average weight of the 10 who took CLA dropped by about five pounds (not enough to be statistically significant), but the body fat percentage dropped by about 15 to 20 percent, or from 21.3 percent of average body fat to 17 percent of body fat. Meanwhile, the group taking a placebo had little or no effect on either. Half of the people in the study were men and half were women. Two people in the study decided to drop out because they received unpleasant gastrointestinal upsets. One of those who dropped out was in the placebo group, the other in the group taking CLA.63 Nobody would suggest that CLA supplementation would be a pill freeing you to sit slug-like on the couch to watch M*A*S*H* re runs. A healthy, weight-conscious lifestyle requires many factors including exercise. As far as science can tell, CLA may not be essential the way certain vitamins are. If you consume no vitamin C, you can expect to get scurvy and die. There are no known deficiency diseases associated with an absence of CLA. Japanese consumers, for example, get very little CLA in their diets, but they also eat food very low in fat, and their lives are among the longest in the world.50 So, the role of CLA supplementation in regulating weight is most useful for those with a typically high-fat Western diet. As the science grows, it seems clear that CLA will lead to better health and more hope for people struggling with body fat.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=397) KudZu, Treatment of alcohol dependence or alcohol abuse
Date:
May 19, 2005 09:29 AM
For millennia, folk medicines have been used to treat ‘‘alcohol addiction’’ in China. A thorough literature search of the ancient Chinese pharmacopoeias revealed a long list of traditional remedies, including the 16 ‘‘stop-drinking’’ formulae of Sun Simiao (ca. 600 AD) and the ‘‘anti-alcohol addiction’’ formula of Li Dongyuan (ca. 1200 AD), 2 of the most reputed ‘‘medical doctors’’ in the history of Traditional Chinese Medicine. However, like those discovered by the ancient Romans,11 most of the ancient Chinese remedies for ‘‘alcohol addiction’’ were based on psychological aversion: to deter patients from further drinking by associating alcohol drinking with an unpleasant experience. Interestingly, as time went by, treatments based solely on psychological aversion were gradually eliminated from the ancient Chinese pharmacopoeias, presumably because of their ineffectiveness and/or undesirable side effects. The only remedies that have survived this historical trial-anderror scrutiny are those consisting the root (Radix puerariae, RP) or flower (Flos puerariae, FP) of Pueraria lobata (a medicinal plant known to the West as kudzu). It was on the basis of this historical backdrop, we initiated the search of safe and efficacious anti-dipsotropic (alcohol intake suppressive) agents from RP. This approach has led to the discovery of daidzin,12 an isoflavone that has since been shown to reduce alcohol drinking in all alcohol preferring animal models tested to date.
Alcohol abuseAlcohol abuse and alcohol dependence (i.e., alcoholism) are serious public health problems of modern society. In the United States alone, an estimated 13 million adults exhibit symptoms of alcohol dependence due to excessive alcohol intake, and an additional 7 million abuse alcohol without showing symptoms of dependence according to U.S. Government projections from studies conducted in the mid-1980s. Alcohol dependence and abuse are very expensive: in economic and medical terms, it will cost the U.S. well over $200 billion in 1991 with no prospect of falling or leveling off. The social and psychological damages inflicted on individuals as a consequence of alcohol abuse, e.g., children born with fetal alcohol syndrome (FAS) and victims of alcohol-related accidental death, homicide, suicide, etc., are immense. While it is generally accepted that alcoholism and alcohol abuse are afflictions with staggering international economic, social, medical, and psychological repercussions, success in preventing or otherwise ameliorating the consequences of these problems has been an elusive goal. Only very recently the public view that alcoholism and alcohol abuse are remediable solely by moral imperatives has been changed to include an awareness of alcoholism and alcohol abuse as physiological aberrations whose etiology may be understood and for which therapy may be found through scientific pursuits. Both alcohol abuse and dependence arise as a result of different, complex, and as yet incompletely understood processes. At present, alcohol research is in the mainstream of scientific efforts. Our studies on alcohol (ethanol or ethyl alcohol) have been based on the hypothesis that its abuse can ultimately be understood and dealt with at the molecular level. Such a molecular understanding, if achieved, would provide a basis for the identification and development of appropriate therapeutic agents. Our view hypothesizes that the clinical manifestations of alcoholism and alcohol abuse are the consequence of aberrations or defects within one or more metabolic pathways, affected by the presence of ethyl alcohol. In order to test this hypothesis, our initial studies focused on physical, chemical, and enzymatic properties of human alcohol dehydrogenase (ADH), the enzyme that catalyzes alcohol oxidation according to the following reaction formula: CH.sub.3 CH.sub.2 OH+NAD.sup.+ .fwdarw.CH.sub.3 CHO+NADH In addition, our studies more recently have focused on the aldehyde dehydrogenases (ALDH) which catalyze the subsequent step in the major pathway of ethanol metabolism according to the following reaction formula: CH.sub.3 CHO+NAD.sup.+ .fwdarw.CH.sub.3 COOH+NADH Prior to our research (for example, see Blair and Vallee, 1966, Biochemistry 5:2026-2034), ADH in man was thought to exist in but one or two forms, primarily in the liver, where it was considered the exclusive enzyme for the metabolism of ethanol. Currently, four different classes of ADH encompassing over twenty ADH isozymes have been identified and isolated from human tissues. There is no reason to believe that all of these ADH isozymes are necessary to catalyze the metabolism of a single molecule, ethanol, even though all of them can interact with it. We have proposed that the normal function of these isozymes is to metabolize other types of alcohols that participate in critical, physiologically important processes, and that ethanol interferes with their function (Vallee, 1966, Therapeutic Notes 14:71-74). Further, we predicted that individual differences in alcohol tolerance might well be based on both qualitative and quantitative differences in isozyme endowment (Vallee, 1966, supra).
Our research has established the structures, properties, tissue distribution, and developmental changes for most of the ADH isozymes, which while structurally quite similar, and presumed to have evolved from a common precursor, are functionally remarkably varied. Of the more than 120 publications from our laboratory that relate to the above subjects, the following, arranged in six categories, are especially useful for instruction in the prior art.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=79) |