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Science confirms turmeric as effective as 14 drugs
March 26, 2019 01:45 PM
If you haven’t yet heard, turmeric is the latest super herb that is as effective as at least 14 drugs and is safe to consume in food, as a tea, or in supplement form. A 2008 study in Drugs found that turmeric worked just as well as Lipitor in decreasing blood levels of cholesterol. Another study in Phytotherapy Research found turmeric to be as effective as steroids in the treatment of chronic inflammatory eye disease. Studies conducted over the past twenty years also show turmeric to be a promising alternative to aspirin, ibuprofen, naproxen, and tamoxifen for its anti-inflammatory and tumor suppressing properties.
"Have you heard of turmeric but weren’t sure if you should start incorporating it into your lifestyle?"
Read more: https://www.healthnutnews.com/science-confirms-turmeric-as-effective-as-14-drugs/
Nutritional benefits that prove moringa really is a "miracle tree"
January 09, 2019 09:15 AM
Known as the miracle tree, the moringa plant has many health benefits derived from its pods, leaves, and seeds. Moringa is grown in northern India and is commonly used by natives in cooking. The seeds of the moringa are rich in both antioxidants and anti-inflammatories, making it very beneficial for those with ulcerative colitis and other GI conditions. Moringa seeds have also been shown to decrease blood sugar levels, making it the perfect superfood for diabetics or those at-risk. Furthermore, moringa seeds can help decrease one’s risk of developing breast, colon, and liver cancers by suppressing the spread of cancer cells.
"Moringa is a good source of healthy monounsaturated fats that lower bad cholesterol and consequently reduce the risk of heart disease. Previous studies have also shown that moringa seeds protect heart cells from damage induced by oxidative stress and excessive inflammation."
Read more: https://www.naturalnews.com/2019-01-03-nutritional-benefits-that-prove-moringa-really-is-a-miracle-tree.html
Study finds that a combination of L-carnitine and vitamin E canovercome immunosuppression
January 04, 2019 08:12 AM
A study has shown that L-carnitine and vitamin E taken together can boost the immune system in response to the immunosuppressing toxin ochratoxin A. The study was conducted with four groups of birds: one that was given the toxin and vitamin E, one given the toxin and L-carnitine, one given the toxin and both supplements, and one given only the toxin. Of the four, the one given both supplements together showed the most resistance to the effects of the toxin, indicating that the combination of the supplements aided the immune system.
"L-carnitine and vitamin E can improve the immune system, according to a study."
Read more: https://www.naturalnews.com/2018-12-27-combination-of-l-carnitine-and-vitamin-e-can-overcome-immunosuppression.html
Inflammation And Its Negative Effect On Our Health
January 07, 2018 03:59 PM
Chronic low-grade inflammation is something that we can experience but many of us don't think about. It is a condition where when our immune system detects a threat in our bodies and substances are released. When they are released and the condition is not cured the substances remain elevated and we then can get chronic inflammation. This can lead to an array of conditions including: cancer, depression, and bone disease, and many more. There are many symptoms of chronic low-grade inflammation and also a holistic way to treat it with functional medicine. Holistically, we can treat by finding the cause and treating that rather than suppressing the symptoms of conventional medicine.
"By reducing the pro-inflammatory aspects of our lifestyle, we will remain youthful and live better for longer."
Read more: http://www.longevitylive.com/anti-aging-beauty/90609/
Olive Oil May Help Prevent and Treat Brain Cancer, Study Shows
June 11, 2017 12:14 PM
Not all fats are bad. Olive oil is a great source of fat which also has health benefits. It is good for the brain. This study shows it can even help with cancer. Olive oil is easy to get into your diet so this is good news. You can substitute this for other oils in many recipes. You can use it in dressings, pasta, rice, baked goods and so much more. It also has a great flavor.
"Given the low survival rate of brain cancer (the five-year survival rate is only about 35 percent)"
Read more: https://www.oliveoiltimes.com/olive-oil-health-news/olive-oil-may-help-prevent-treat-brain-cancer-study-shows/57204
Drink This In Bed BEFORE Getting Up To Drop Weight, Reduce Inflammation And More
March 20, 2017 06:44 AM
If you drink one thing in bed before getting up to drop weight, you can reduce inflammation and more. If you have very rushed mornings, then it can be quite a challenge to slow down and take care of basic things like hydration. If you want to try this amazing recipe, then you will make it before you go to bed.
"But what if slowing down and drinking this elixir before you even got out of bed could improve your morning routine, your mood and your waistline?"
Curcumin helps to effectively ease inflammatory bowel disease: China mouse study
February 21, 2017 07:59 AM
Curcumin, a substance in turmeric, can halt progression of inflammatory bowel disease. Researchers in a leading Chinese university induced colitis in mice and treated them with the substance. Mice treated had a decrease in inflammatory cell infiltration into the colonic mucosa. It does this by suppressing dendritic cell activation which are responsible for creating bowel inflammation.
"Curcumin can help suppress the activation of dendritic cells (DCs), which play a pivotal role in the progression of inflammatory bowel disease, research from China has discovered."
How does CBD help with Seizures
Seizures are the sudden changes in the brain's electrical activity. It usually affects how a person acts for a short period of time or appear. The symptoms of seizure include a loss of control and violent shaking. There can be several causes for the seizures. Anything that affects the brain's normal activity can lead to seizures. Several causes of seizures include injury to the head, fever, disease or even certain uses of medications. A person suffering from regular seizures due to brain disorder is called to be having epilepsy. Seizures can take different forms that affect many people in different ways, as some people call it electrical storms in the brain.
CBD has several therapeutic effects. Unlike THC, CBD has a less binding affinity to the CB1 and CB2, those are Cannabinoid receptors. Instead, CBD stimulates endogenous cannabinoid signal by suppressing enzyme fatty acid amide hydroxylase (FAAH). CBD helps in enhancing endocannabinoid by suppressing FAAH. CBD also opposes the action of THC at CB1 receptor, thus help to mute the effects of THC. CBD also stimulates 2-AG, that activates the CB1 and CB2 receptors, where CB2 receptors are predominant in the immune system and peripheral nervous system. It is found that CBD binds directly with 'G-protein' coupled receptors and other ion channels to grant therapeutic effect. CBD is also known as the TRPV-1 stimulant that helps, CBD-rich Cannabis in the effective treatment of the neuropathic pain.
The Top 15 Natural Appetite Suppressants
December 07, 2016 10:59 AM
It is often difficult to control your appetite. We all wish there was a pill or supplements that would make it easy to control cravings. JetFuel Accelerator adds to our list as one of our top appetite suppressing supplements. Obesitrol placed on our list because of its impressive ingredients. Animal Cuts is designed and formulated by Universal Nutrition to create 9 different complexes earning itself a place on this list.
"These supremely healthy drinks, foods, and spices can curb your hunger, help you lose more weight, and stick to your diet plan."
What Is the Malibu Miracle Weight Loss Program?
If you want to shed some pounds quickly and easily, then Malibu Miracle weight loss program is what you need. The exotic berry Malibu Miracle formula produces amazing noticeable results that will get you slimming sooner than you thought. Malibu Miracle contains a blend of highly effective and concentrated blend of succulent fruits including Gogi, Noni, Mangosteen, Pomegranate and Acai. With this, you can have a wholesome nutrition that will support your body cleansing as well as experience an exhilarated state of well-being. Malibu Miracle juice is delicious and is charged with metabolism-supporting botanicals which include L-Carnitine, Super Citimax, Green Tea, Red wine, prebiotic fructooligosaccharides and Grape seed extract.
How Does The Malibu Miracle Weight Loss Program Work?
The Malibu Miracle formula contains oxygen-enhanced revitalized water that has vitality-enhancing, rehydrating and energizing properties that work naturally. That way, you can experience superior hydration, cellular health as well as an improved body health. However, when managing your weight, don’t expect miracles to happen from nowhere. It will take your hard work, determination, healthy diet and exercise program for you to realize the desired results. Malibu Miracle only serves as a supplement for a comprehensive diet and exercise program. Malibu Miracle’s line has cutting-edge formulas that will produce lightning-fast results for better living. It is amazing how you can be on your way to an improved body size and shape in as little as 48 hours. The products contain exotic natural ingredients that are combined with the latest advancements in weight nutrition. In addition to that, the Malibu Miracle juice is incredibly sweet so you have every reason to buy one for your weight loss program.
Where Malibu Miracle 48-hour juice didn’t do better, the Exotic Oxyjuice introduced Ultra Malibu Miracle. The breakthrough juice fast program comes in 6,000 mg each of real antioxidant-rich red super fruit juices ranging from Mangosteen, Noni, Goji, Pomegranate and Acai. These combination of juices kick-start the rapid weight loss in your body and also deliver nutrients which catalyze cascading full-body cleansing. On top of that, the Ultra Malibu Miracle contains Slendesta - a potato protein extract with ultimate appetite control properties- which helps you feel full and completely satisfied all day long.
All other competing juice fasting products can’t match Malibu Miracle and Ultra Malibu’s ability to deliver excellent results. These two products work great in suppressing appetite, providing anti-oxidant protection, supplying health-supporting nutrients and cutting weight within the shortest time. All that is contained in the lusciously delicious and mixed-berry juice concentrates.
Does Malibu Miracle Have Any Side Effects?
Malibu Miracle contains no artificial colors nor sweeteners. All the ingredients are naturally sourced and so you should expect minimal or no side effects while on your weight loss program. It is always advisable that during juice fasting diet, you abstain from food, alcohol, caffeine and smoking. Juice fasting is not recommended for pregnant women, lactating mothers or people with medical conditions or those that are on medication of any kind.
As with all diets, results might vary with each individual. It also depends on how much you exercise so you need to balance things out to get the desired results. However, it is important to remember that juice fasting for consecutive 48-hour periods is not recommended.
Does Garcinia Help With Weight Loss?
Garcinia cambogia, a tropical fruit obtained from a herb called Malabar tamarind, has for a long time been used as a weight loss supplement. Garcinia cambogia is found to grow naturally in South East Asia and some parts of Indonesia. Traditionally, this herb was used as food flavor by traditional communities in India. The fact that this supplement is obtained naturally implies that it has minimal side effects when used for weight loss by an individual.
How does Garcinia cambogia works?
The critical component that gives Garcinia cambogia its weight loss property is called hydroxycitric acid or simply HCA. Garcinia cambogia works through;
What determines the success of Garcinia cambogia in any weight loss program is the concentration of HCA. The recommended HCA concentration that you should buy is 60%. Moreover, it is also imperative to consider shopping for the Garcinia cambogia products that are certified and approved by the Food and Drug Administration. This is to ensure that what you are shopping is safe and suitable for all your individual weight loss needs.
Does Broccoli Really Fight Cancer?
May 27, 2014 05:23 PM
What is a broccoli?
Cruciferous vegetables such as broccoli is known to have numerous health benefits within the body. In addition, many studies have proved that broccoli has another element known as sulforaphane that has cancer-fighting properties.
Benefits of broccoli
A recent study by the Oregon State University, suggested that sulforaphane is a powerful antioxidant in broccoli and many other cruciferous vegetables do have the power and the ability to kill cancer cells, thus leaving the prostate cells unaffected.
Sulforaphane is also another potent antioxidant that has the ability to inhibit HDAC enzymes known as histone deacetylase and play a vital role in suppressing tumor-like genes thus making a perfect solution to cancer treatment. HDAC in Cruciferous vegetables such as broccoli is known to have numerous health benefits within the body. In addition, many studies have proved that broccoli has another element known as sulforaphane that has cancer-fighting properties.
A recent study by the Oregon State University, suggested that sulforaphane is a powerful antioxidant in broccoli and many other cruciferous vegetables do have the power and the ability to kill cancer cells, thus leaving the prostate cells unaffected.
Sulforaphane is also another potent antioxidant that has the ability to inhibit HDAC enzymes known as histone deacetylase and play a vital role in suppressing tumor-like genes thus making a perfect solution to cancer treatment. HDAC inhibition is another very promising cancer treatment and many researchers have found that it is associated with broccoli. Cancer is often characterized by the inappropriate cell growth, however, HDAC inhibitors has the ability of restoring cells to normalcy in terms of function and thus the most effective cure of cancer.
Other studies have also demonstrated the cancer-fighting ability of the cruciferous vegetables. In the year 2009, Victoria Kirsh., of Toronto Cancer Care Ontario and her team discovered that eating vegetables and fruits in general was associated with the decreased prostate cancer risk, making it one of the best ways of enhancing health. This remarkable compound in broccoli is among the strongest anti-cancer elements in the body.
It is important to recall that you cook your broccoli in the best way possible since this will preserve the elements that helps in fighting cancer. In addition, Broccoli has myrosinase that helps in the formation of sulforaphane. You need to remember that Myrosinase is an element that can be destroyed through overcooking the broccoli. You should only steam it for 2 to 4 minutes. In conclusion, the above information should convince on the incredible ability to cure the cancer cells that are found within the body.
Benefits of Boswellic Acid To The Body
April 20, 2014 08:25 PM
Benefits of boswellia
Rarely do people bank on herbs for treatment. Chemically manufacture medicines have taken over. However, what makes Boswellia herb very important? This herb has been used for a very long time. It is extracted from the Boswellia serrate tree. This herb is popular among other pharmacological medicines because of its medicinal values of reducing the effect of inflammation and inflammation related diseases.
What is inflammation?
Our body goes through very complex biological processes to keep us healthy. Inflammation is one of them. Inflammation has been the response action that the body takes towards an intruder. The body does this by producing prostaglandins and leukotriene; they are otherwise called inflammation mediators. Most of the time, the intruder can be harmful stimuli or pathogens and damaged cells. The body responds by causing acute pain in places like toes and fingers. Besides the pain, heat, swelling, redness and loss of function are signs of inflammation. Note that inflammation is not an infection.
Examples of inflammatory disease
Examples of inflammatory diseases are bronchial asthma that leads to narrowing of the respiratory tract and makes breathing difficult. Diabetes, type 1 is an inflammatory disease that is caused by the inflammatory mediators. They eat up the pancreas until it is exhausted. Production of insulin to counter diabetes will be affected largely.
How boswellia works
Boswellia releases boswellic acid. This is the main ingredient that is used to fight and heal inflammation. It does this by suppressing the release of prostaglandins and leukotriene. Bowellic acid comes in many forms. Acetyl-11-keto-B is one example that when released, inhibits the synthesis of enzymes that will produce leukotriene hence lead to inflammation. Constant use of this herb heals and prevents the body from inflammation diseases.
Besides healing inflammation diseases, boswellia reduces the effects of brain cells tumor and colon cancer. The herb can be used to activate tumor suppression genes, a genes that will control and eventually reduce the growth of cancer cells.
What Are The Health Benefits Of Inositol Crystals?
December 28, 2012 10:39 AM
The first isolation of inositol was made by Scherer in the year 1849 who was a renowned Biochemist at the time. Since its discovery, wide spread research has been conducted with successful isolation of inositol and its derivatives in both plants and animals. The physiological functions have been confirmed to differ with respect to the structural form of the inositol, with cis-inositol, myo-inositol, neo-inositol and allo-inositol being some of the inositol's stereoisomers commonly isolated.
Our Need for Inositol
The human body particularly requires inositol and its derivatives in many physiological processes. It is a major messenger molecule that is used in calcium mediated cell signaling which affects motor function, action of hormones such aldosterone and affects the functioning of some of the neurotransmitters in the brain such as serotonin. Inositol derivatives are also involved in lipid metabolism which helps control the amount of LDP (Bad cholesterol) in the body.
Additionally, some of the researches indicate that inositol derivatives are actively involved in suppressing oncogenesis which significantly reduces the risk of suffering from breast and prostate cancers. The human body can produce some of the inositol variants from glucose metabolism but obtaining plant derived inositols is also worthwhile.
Food Sources Of Inositol
Plant products such as red beans, bran and other cereals contain good levels of inositol although the chelating effect of the inositol by calcium and magnesium ions limits its uptake in the gut. For this reason, use of supplement Crystal Inositols is regarded as the best way to obtain dietary inositol. A majority of the crystal inositols available in the market are chemically combined with other compounds such as Niacin which highly increase their absorption in the intestines. Dissolving these crystals in juices is also highly recommended as it is a better way of taking the supplements since a wide range of other drinks especially the ones that contain caffeine affects the uptake of inositol negatively.
November 22, 2012 11:03 AM
Among beverages, many varieties of tea exist including oolong, green and black tea. they are in fact quite similar in their natural state and chemical composition. However, the benefits of black tea extract has begun proving its mettle after the rather heavy overdose of information and research on green tea. The important ingredient that has made tea a rage in alternative medicines in the modern times is the contents of polyphenol which is beneficial in reducing fat absorption and aiding weight loss. In fact, while green tea extract has about 30-40% of water soluble polyphenol, black tea has about 10% .
What has however been proven through recent clinical studies is that the four kinds of polyphenols found in black tea extract are more active on adipose tissue mass, liver lipid content thereby suppressing body weight more effectively as compared to green tea. Green tea is the fresh plucked leaves of the camellia sinesis plant while black tea extract is made from the fermented leaves. While the green tea leaves are only lightly dried, black tea leaves are fully oxidized. Both contain flavonoids known for their beneficial effects on the human body .
However because of the excessive oxidation in black tea, the flavonoids convert to complex theaflavins and thearubiglins.These are antioxidant known to be tremendously potent in effectively countering cancers, stroke and heart ailments. Potent Health Benefits *Its proven to affect on triglycerides present in the blood thus affecting body weight issues dramatically. In fact clinical observations have proved that it induces reduced levels of cholesterol with no side effects on fat soluble vitamins.
It's safe usage could not have been proved better:
An intake up to three cups is said to have beneficial effect but again discretion should be maintained in cases of hypertension, blood pressure and anxiety, who could do without the effect black tea extract has on blood circulation and heightening of alertness.Without a doubt black tea extract remains one of the most common proven natural formulas with great benefits.
What Is Vitamin B-2 Riboflavon Good For?
November 17, 2012 02:11 PM
Vitamin B-2 is one of the B-complex, water soluble vitamins that is required for the proper functioning of the human body. They can be found in different dietary sources including but not limited to eggs, dairy products, grains and cereals, green vegetables, mushrooms, oily fish and meat.
A B-2 Deficiency:
It is concluded that the deficiency in this vitamin can disrupt the metabolism of carbohydrates, fats and protein. Symptoms of deficiency includes high sensitivity to light, inflammation the mouth, sore tongue, anemia, skin rash and fatigue, and it affects mostly malnourished people like alcoholics and the elderly.
Benefits of vitamin B-2 Riboflavin.
Apart from helping to increase the level of body metabolism, the vitamins is also useful in helping to prevent and treat diseases e.G. Riboflavin deficiency states and newborn jaundice. It can also help for the prevention of cataracts of the eyes and reduce migraine headaches intensity. Riboflavin plays a major role in the development of reproductive organs. It also help to support the growth of body tissue like the skin, nervous system, mucous membranes and the connective tissue. vitamin B-2 helps to improve the body immunity by energizing the body's natural defense and disease suppressing systems. Known to be very helpful as a natural supplement in the treatment of nervous system conditions like Alzheimer's disease, multiple sclerosis and epilepsy.
Constant intake of vitamin B-2 will help in the digestion of carbohydrates, fats and protein so that the body cells can derive more minerals and vitamins from them, for utilization. Absorption of other vitamins and minerals like folic acid, vitamin B1, Iron and vitamin B6 is also made very possible.
To have stress free digestion you'll need to have a digestive system with functioning mucus membranes. Riboflavin is helpful in making the mucus membrane in the digestive track work at optimum levels. Recent research also suggests that vitamin B-2 can help improve the body's response to iron therapy, which is a method used to boost red blood cell production in sickle cell anemia patients.
So my question to you is, are you getting enough B-2 in your daily diet?
What Are The Health Benefits Of Saffron Extract?
March 26, 2012 08:01 AM
HEALTH BENEFITS OF SAFFRON EXTRACT
Saffron is one of the rarest and exotic spices found on the earth. Golden spice is the other name given to saffron, attributing to its reddish-golden color. It is the most common spice used in many Indian,Mediterranean and Italian cuisine. This culinary and exotic spice grows on a flowering plant- Crocus Sativa. It is grown in various countries around the world including many Asian and European countries. Areas with hot dry summers and wet springs are the most suitable areas for growing Saffron. While saffron is popular for its flavor, color and fragrance, this rare spice also, has many medicinal and health benefits. Saffron is a very expensive spice and this is mainly because of the fact, that for making 1gram of Saffron strands 150 flowers are required.
Mineral present in Saffron extract -
Saffron extract contains high amounts of copper, magnesium, calcium, zinc, potassium, iron, and selenium. It is also a rich source of various vitamins like- vitamin A, B2 and C, niacin and folic acid. Apart from these Saffron also contains carotenoid compounds - crocetin, lycopeneand, safranel and crocin.
The various health benefits of Saffron are -
1) Cancer Treatment- Because of the presence of crocetin and carotenoid in Saffron, it has anti-mutagenic and anti-tumor properties. Several studies on Saffron extract have proved that Saffron extract delays papilloma carcinogenisis and tumor growth. Because of all these properties, Saffron extract can be used for treating and preventing skin cancer, liver cancer and sarcoma.
2) Anti-inflammatory properties- Saffron have anti-inflammatory properties and therefore it can be used in treatment of arthritis and other inflammatory diseases. It is capable of controlling inflammation and healing cuts and burns faster.
3) Potent aphrodisiac- For last many centuries, Saffron has been used as a “POTENT APHRODISIAC” inPersiaand many other Arabian countries. It can increase libido and improve erectile dysfunction by increasing the flow of blood in the pelvic region.
4) Eye Care- Several studies have proved that Saffron extract can treat certain eye problems like- macular degeneration and retinitis pigmentosa. Saffron also protects the eyes from the harmful effects UV rays.
5) Anti-Depressants- Saffron extract can also be used in the treatment of patients suffering from depression. Researches have shown that Saffron gives equal results as given by therapeutic drugs like imipramine and fluoxetine.
6) Painkiller- Saffron extract can be used for treating many severe painful conditions like- stomach pain, menstrual pain, and kidney pain.
7) Weight loss- Researches have shown that Saffron can suppress the feeling of hunger, by controlling the percentage of serotonin content in the blood. Therefore, Saffron is used in many weight loss programs, as it can reduce the compulsion to eat and feelings of hunger.
8) Skin- Saffron contains antioxidants, and therefore it is used in many beauty and anti-aging treatments.
9) Saffron during Pregnancy- During pregnancy, women are advised to drink Saffron milk, in order to enhance their pelvic blood flow. Also, due to its Carminative properties it helps in suppressing cramps.
Gas and bloating are very common problems during pregnancy and just one glass of Saffron milk can reduce flatulence and ease digestion.
Hoodia For Weight Loss
September 18, 2009 10:20 AM
The hoodia plant is a leafless, spiny plant. It is a succulent in the milkweed family. Hoodia can be found growing in South Africa and Namibia. The plant thrives in very high temperatures, taking years to mature. Bushmen from the Kalahari Desert in southern Africa have used hoodia for centuries to help fight off hunger during long treks in the desert. This ancient band of nomadic hunter-gatherers eats bite-size chunks to stave off thirst and curb their appetites on long hunting trips in the wilderness.
In early 2004, the first supplements containing a hoodia compound were introduced in the United States. These supplements were intended to be an aid for obesity and weight loss. Hoodia contains an appetite-suppressing component that is similar in molecular structure to glucose, only stronger. This component is known as P57. It is responsible for sensing a signal to the hypothalamus which tricks the body into thinking it is no longer hungry. The P57 compound seems to increase the amount of ATP in nerve cells of the hypothalamus, which is the brain’s control center for regulating thirst, hunger, and temperature. ATP is an energy-producing molecule that is created from glucose. When ATP levels are increased in hypothalamic nerve cells, those nerve cells fire as if you had just eaten, even if you haven’t.
Some people claim that hoodia works immediately for them, within twenty to thirty minutes of taking the capsules. However, more often, people require up to two weeks of taking regular doses before they start noticing significant results. These results include a reduced interest in food, a prolonging of time after a meal before being hungry again, feeling full more quickly, and a general sense of well-being.
Studies that have been done on the effects and safety of hoodia are continuing in the United States and abroad. The prospects for the future development of this herb look very promising.
Don’t make the mistake of believing that all you have to do is take a supplement of hoodia everyday and the fat will just disappear. While some claim that has been the case for them, the majority of dieters need more help than solely diet pills. It should be remembered that the only thing the hoodia does is suppress appetite. It does not improve a bad diet or address problems of overeating. It you have a terrible diet and ten to overeat even when you are not hungry, you will not receive any benefits from hoodia. If these things describe you, you first need to tackle those issues before considering hoodia. This herb will not build muscle or burn fat. Your muscles are fat burning machines and responsible for burning fat all day long, even when you are resting. The more you have the more fat you’ll burn. Your metabolism also plays a huge role in burning fat. The only way to build muscle and speed up your metabolism is to exercise.
The stem of the hoodia plant is used to provide anorectic, aphrodisiac, and mood enhancer properties. Primarily, this herb is extremely helpful in treating diabetes, obesity, and weight loss. For more information on the many beneficial effects of hoodia, please feel free to contact a representative from your local health food store.
February 26, 2009 12:43 PM
Motion sickness is the result of motion causing the eyes, the sensory nerves, and the vestibular apparatus of the ear to send conflicting signals to the brain, causing a loss of equilibrium or a sense of vertigo. Most often, it is experienced in a car, airplane, train, boat, elevator, or swing. Contributing factors to this illness are anxiety, genetics, overeating, poor ventilation, and traveling immediately after eating. A susceptibility to things like offensive odors, sights, or sounds can often precede an attack of motion sickness. Typically, women are affected by this condition more frequently than men are. Elderly people and children under the age of two are usually not affected.
Those people who suffer from motion sickness experience symptoms including severe headaches, queasiness, nausea, and vomiting while flying, sailing, or traveling in automobiles or trains. Other symptoms of motion sickness include cold sweats, dizziness, excessive salivation and/or yawning, fatigue, loss of appetite, pallor, severe distress, sleepiness, weakness, and occasionally, breathing difficulties that make one feel as if they are suffocating. If motion sickness is severe, an attack can make a person feel completely uncoordinated, and sometimes and injury can occur from loss of balance. The motion sickness typically goes away once the stimulus is removed. However, it can also persist for hours or days. If a person suffers from motion sickness for a prolonged amount of time, they may experience depression, dehydration, or low blood pressure. Motion sickness can also worsen any other illnesses that a person already has.
Many natural remedies have been greatly successful in treating motion sickness. The prevention of motion sickness is the key, as it is far easier to prevent than it is to cure. Once excessive salivation and nausea set in, usually it is too late to do anything but wait for the trip to be over so that recovery can begin.
The following nutrients have been recommended to help prevent motion sickness. Unless otherwise specified, the dosages given are for adults. For children between the ages of twelve and seventeen, the dose should be reduced to three-quarters of the recommended amount. For children between six and twelve, one-half of the recommended dose should be used, while one-quarter of the amount should be used for children under the age of six.
Charcoal tablets can be used as a detoxifier. Five tablets should be taken one hour before travel. Magnesium, which acts as a nerve tonic, should be taken in dosages of 500 mg one hour before a trip. To help relieve nausea, 100 mg of vitamin B6 should be taken one hour before a trip, and then 100 mg should be taken again two hours later. Additionally, black horehound can help to reduce nausea. Butcher’s broom, kudzu, and motherwort are great for helping to relieve vertigo. Ginger is beneficial in suppressing nausea, making it an excellent treatment and preventive for nausea and upset stomach.
Lastly, peppermint tea sooths and calms the stomach. Also, a drop of peppermint oil on the tongue is a great way to provide relief from nausea and motion sickness. Peppermint can also be taken in a lozenge form. To learn more information about the above nutrients, contact your local or internet health food store.
Hoodia Extract And Appetite
September 26, 2008 11:36 AM
Hoodia is a plant that belongs to the milkweed family and consists of about twenty different species. It is a leafless, spiny plant, with fleshy finger-like stems. Along the stems, there are rows of thorns, while the plant bears flesh-colored flowers. Flies are attracted to the flowers by the strong smell of decaying meat, causing the flies to lay their eggs and pollinate the flowers. Sometimes spelled hootia, hodia, hoodie, and hudia, hoodia has recently gained a great amount of attention in the United Kingdom and America after being featured on BCC and CBS. Often growing in summer rainfall areas in Angola, Botswana, Namibia, and South Africa, along with winter rainfall areas in Nambia, hoodia gordonii is the only species that contains the chemical component that suppresses appetite.
Hoodia has been used for thousands of years by San Bushmen, as it populates the arid territories of South Africa and Namibia. Because San Bushmen needed to remain active in order to survive, they had little need for dieting, but this plant provided them with stamina and a curbed appetite during long periods without food. Along with reducing or eliminating the desire for food, many people believe that hoodia also increases energy and can act as an aphrodisiac on the user.
The appetite-suppressing ingredient found in hoodia is a molecule that is similar to, but stronger than glucose. The active compound that was isolated to be responsible for appetite suppression is P57, which works by sending a signal to the hypothalamus of the brain, tricking the body into thinking that it is no longer hungry, and resulting in a complete lack of appetite. P57 is a steroid like molecule that is chemically bonded to a chain of three sugar molecules. The appetite-suppressing and mood-enhancing properties of P57 go directly to the mid-brain, where it causes neuron cells to fire as if you were full.
The hypothalamus is the region of the brain that contains several important centers which control body temperature, thirst, hunger, water balance, and sexual function. Additionally, the hypothalamus is closely connected with emotional activity and sleep and also functions as a center for the integration of hormonal and autonomic nervous activity through the control of pituitary secretions. In short, the hypothalamus links the nervous system to the endocrine system. The pituitary gland is often thought of as the mater gland in our bodies, as the anterior and posterior pituitary secrete a variety of hormones that influence all cells and affect almost all physiological processes.
The pituitary gland is powered by the hypothalamus, as some of the neurons in the hypothalamus secrete the hormones that are responsible for controlling the secretion of hormones from the anterior pituitary. The inhibiting and releasing hormones of the hypothalamus are carried directly to the anterior pituitary where hypothalamic hormones bind to receptors on anterior pituitary cells.
The P57 hormone that is found in hoodia works by increasing the amount of ATP in nerve cells found in the hypothalamus. ATP is an energy-producing molecule that is formed from glucose. When there are increased levels of ATP in hypothalamic nerve cells, those nerve cells fire as if you had just eaten, even when you haven’t. Hoodia is a safe herb taken for hundreds of years, have you tried Hoodia lately?
Hyper-immune Egg Vs Colostrum
September 23, 2008 03:36 PM
When a hen lays her eggs she is virtually an antibody-producing factory, as she passively transfers her antibodies and immunoregulatory factors into the egg in order to protect her offspring. These eggs are made up of a concentrated source of antibodies and helpful immune-supporting biomolecules. However, there are significant differences in the way a cow passes immune protection to a calf and the way a mother hen passes protection to a chick.
A newborn calf will nurse for several months, acquiring immune support over the entire period of time. Since a mother hen cannot nurse her chick, it is essential for the egg to provide all the immune support a chick will need until its own immune system is functioning properly. Because of this, an egg is much more concentrated in antibodies and immunoregulatory molecules than is colostrums. This is an advantage for using hyperimmune egg over supplements that are made from bovine colostrums as an immune system support. It has been found that chickens produce almost twenty times more antibody per unit of weight than cows are able to secret in their milk. Additionally, certain egg antibodies are compared to milk antibodies, and it has been found that egg antibodies seem to be more effective in binding antigens.
In order to produce a hyperimmune egg supplement, the following procedure must be followed. First, eggs are collected from the specially designated chicken flocks after they are specifically stimulated. They are then washed and broken. The yoke of the egg white is then removed and dried to produce a find proteinous powder. There have been various processes developed to minimize the amount of heat damage to antibodies and immunoregualtory factors during the spray-drying procedure. The immune eggs are required to be processed under good manufacturing practices in USDA-inspected and monitored facilities. After processing occurs, the powders are combined with other vitamins, minerals, and possibly other ingredients in order to form a formula that possesses a high nutritive value.
Unlike the conventional methodologies, hyperimmune eggs seems to team up with our immune system instead of boosting or suppressing its function. The immune products in hyperimmune egg are a resource for the body. The body is then able to select those immune elements that it needs in order to up or down-regulate the autoimmune and inflammatory pathways.
Because our immune systems are under constant attack, immune disorders are increasing at an alarming rate. Recent research has found that immune malfunction is an important contributing factor to conditions including heart disease, arthritis, and auto immune disorders. By fine-turning and supporting our immune system in order to prevent disease, we can make one of the best investments possible for our health and longevity.
The potential value of using hyperimmune egg for various health conditions has been shown by new research. Some of the most well-known doctors using alternative and complementary health treatments have found that hyperimmune egg supplements are extremely helpful in reversing a wide array of health problems. As research continues and understanding of how hyperimmune egg works increases, the application of hyperimmune egg can be expected to increase. Impressive properties found in hyperimmune eggs make them an excellent supplement for immune support. When we have a balanced and well-functioning immune system, our lives will be much healthier and happier.
August 15, 2008 03:51 PM
DHA is the most abundant essential fatty acid (polyunsaturated fatty acids) found in the brain and retina. DHA is essential for the proper functioning of our brains as adults, and for the development of our nervous system and visual abilities during the first 6 months of life. DHA is found in cold water fatty fish, including salmon, tuna (blue fin tuna have up to five times more DHA than other types of tuna), mackerel, sardines, shellfish, and herring. Lets take a look at what DHA can do for you.
DHA makes infant formulas more like human milk than "conventional" formula containing Alpha-linolenic acid and linoleic acid, which are precursors to DHA. It has been an ingredient in several brands of premium infant formula sold in North America since 2001. Mead Johnson was the first infant formula manufacturer to add DHA and ARA (arachidonic acid) to its Enfamil Lipil product, several other manufacturers have followed. DHA levels in breast milk are higher if a mother's diet is high in fish.
DHA is also present normally in very high concentrations in the retina. DHA supplementation would be particularly important for mothers who have consumed excessive alcohol, because alcohol inhibits the desaturase enzymes necessary for DHA synthesis. Docosahexaenoic Acid (DHA) is a type of Omega-3 fatty acid, a nutrient that has been studied for its role in heart, brain and eye health. An experiment that studied the individual effects of EPA and DHA found that EPA reduced natural killer (NK) cell activity and cell-mediated immune response, but that DHA does not so this study concluded that the immune-suppressing effects of fish oil are mainly due to EPA, not DHA.
Omega-3 fatty acids found in fish oil help lower triglycerides (fats in the blood), lower blood pressure, reduce the risk of blood clots, improve the health of arteries and reduce the amount of arterial plaque (which narrows arteries and causes heart disease). Many people believe that excessively high omega-6 rather than omega-3 in the modern diet is responsible for an increase in allergies and the need to take aspirin to reduce the risk of heart attack (myocardial infarction).
Sunflower, safflower and corn oil are particularly rich sources of linoleic acid, which is at the root of the omega-6 fatty-acid family. The ability of enzymes to produce the omega-6 and omega-3 family of products of linoleic and alpha-linolenic acid declines with age this is why we need more omega 3 DHA in our diets. In fact, a high omega-3 fatty acid diet increases the alpha-tocopherol content of heart muscle membranes by five times, and this effect is most prominently associated with DHA because the heart muscle prefers DHA as its raw materials to manufacture and strengthen its membranes.
Dietary DHA may reduce the risk of heart disease by reducing the level of blood triglycerides in humans. Low levels of DHA result in reduction of brain serotonin levels and have been associated with ADHD, Alzheimer's disease, and depression, among other diseases, and there is mounting evidence that DHA supplementation may be effective in combating inflammatory bowel disease as well.
Dietary changes in the past century have lowered the consumption of omega-3 to a state of subclinical deficiency that is epidemiologically related to cardiovascular disease, inflammatory disorders, mental and psychiatric diseases and suboptimal neurodevelopment. Decreases in DHA in the brain are associated with cognitive decline during aging and with onset of sporadic Alzheimer disease. DHA has a positive effect on diseases such as hypertension, arthritis, atherosclerosis,, adult-onset diabetes, mellitus, thrombosis, and some cancers.
In conclusion, if consuming DHA through your diet is impossible, you can purchase DHA as a supplement in two common forms: Fish oil capsules or DHA extracted from algae. Consuming DHA may help support body tissues in which DHA is prevalent — especially the brain, nervous system, heart, retinas, and colon. Staying healthy is important, have you had your DHA today?
July 08, 2008 03:00 PM
Garcinia cambogia is a small tree bearing a small pumpkin-like fruit of the citrus family, and is steadily appearing in an increasing number of weight loss supplements. It is indigenous to parts of Africa and Asia, and the rind is commonly used in Indian cookery.
Although the fruit is particularly sour to the taste, it is used in form of an extract of the rind and claimed to act as an appetite suppressant and also to increase the body’s capacity to metabolize fat. Although there are conflicting claims being made about its efficacy, or lack of it, research shows that it definitely has promise as an agent to prevent and fight obesity and its use is steadily increasing in this respect.
The active ingredient is hydroxy citric acid, otherwise known as HCA, contained in the form of the potassium and calcium salts of the acid in the aqueous extract of the garcinia cambogia rind. It forms up to 30% by weight of the rind. It is tasteless and odorless, and so far found to have no toxic effects on humans. Animal studies have also been generally favorable.
HCA works in two specific ways both to reduce the desire to eat and to inhibit the storage of fat in the body. In each case, as with so many supplements that have an inhibitory effect on a physiological or psychological function or on a metabolic process, it involves an interaction with enzymes.
Citrate lysase is an enzyme in the body that helps to prevent lipogenesis and instead promotes the conversion of carbohydrates into fat. When this enzyme is inhibited from carrying out its intended part in the body’s metabolism, the process of carbohydrate oxidation is boosted, or, in other words, the excess carbohydrate is burned off, or changed into energy.
More fats could also be expelled unchanged from the body, but irrespective of that the end result is that less carbohydrate tends to be converted to fat. Garcinia cambogia, however, has not been found to reduce the body’s uptake of essential fatty acids which are necessary for health. Had this occurred, you would feel a raging hunger as opposed to the appetite suppressing properties the extract is claimed to have.
The oxidation of carbohydrates can also lead to thermogenesis, or the boosting of the metabolism by increasing your body temperature. An increase in the metabolic rate helps weight reduction through an increased calorie demand while your body is at rest. However, that is not the only way in which the HCA extract works to help reduce your weight, or at least help to maintain it at a healthy level. Let’s return to its specific appetite suppression properties.
Serotonin (5-hydroxytryptamine) is a neuroreceptor found in the central nervous system. It has many regulatory effects on the body, one of which is appetite. Although it is by no means the only chemical in the body that has an effect on the appetite, serotonin is a significant factor. As you get hungry, serotonin is released in the hypothalamus, an area of the brain that regulates sleep and eating. The release of serotonin increases when you see and or smell food. It is the agent that starts canine salivation, and a ravenous hunger in those that have no immediate access to food.
It also causes you to snack, and, as you eat, the serotonin level in the hypothalamus continues to increase until it reaches a point where it provides the hypothalamus with a feeling of repletion or satisfaction. You then stop eating. So the more serotonin is produced, the quicker you stop feeling hungry.
Garcinia cambogia extract has the effect of stimulating the emission of serotonin into the hypothalamus, and so suppresses your hunger quicker. You don’t stop eating altogether, but attain that feeling of satisfaction much quicker and so tend to eat less with each meal. This can not only help you maintain your weight at a healthy level, but also to reduce weight in the obese.
Although the extract can work through each of these mechanisms, it does not have such a significant effect on a very fatty diet. It can help if you switch to a relatively healthy diet, lower in fats, but the effect might not be strong enough to compensate for a poor diet in terms of fat content.
Studies have indicated an anti-oxidant activity that likely comes from the xanthones and xanthone derivatives that are also contained in the fruit. In fact there are other recorded uses of garcinia cambogia, and it has been used in traditional Indian medicine to treat fevers, dysentery, open wounds, ulcers and tumors.
According to a study carried out for the National Cancer Institute there is no documented toxicity effects on humans, and there is no regulation regarding the use of garcinia cambogia. It has not been evaluated by the FDA.
However, there are contra-indications in the case of pregnant and lactating women, more as a safety measure than for any particularly known risk. Alzheimer patients should avoid taking HCA since there is a possibility of it promoting the synthesis of acetylcholine in the brain, and its glycemic action renders it unsuitable for diabetics.
Conversely, this same action is a positive benefit by reducing the craving of healthy adults for sweet foods. However, HCA is frequently taken in combination with chromium due to the latter’s positive effect on the regulation of blood sugar levels. Nevertheless, diabetics should avoid any supplement containing chromium without professional medical advice.
The supplement should be standardized on the HCA content, and an average dose is around 500 mg – 1000 mg of 50% extract a day. However, this varies, and the most important aspect of such extracts is that when changing brands; be sure to compare the strength of the relative extracts and change your dosage accordingly.
Although the benefits of garcinia cambogia to those seeking to lose weight are debated, there is ample evidence to suggest that a regular intake of the extract is beneficial – and not only with respect to the maintenance of healthy weight.
Pinolenic Acid - Appetite Control
April 25, 2008 02:50 PM
Mention "pine nuts" and peoples’ mouths are apt to start watering for a taste of garlicky pesto or fragrant pilaf. Ironically, the same ingredient that is so irresistible in gourmet cooking may help curb our out-of-control appetites. But only a particular variety of pine nut—Pinus koraiensis from Korea—will do.
Source Naturals PineSlim is a Korean pine nut oil (PinnoThin™). A small-scale study suggests that PineSlim may reduce feelings of hunger by increasing concentrations of appetite-suppressing hormones. The study also suggests that a feeling of fullness is experienced 30-60 minutes after taking PineSlim. For best results, PineSlim should be taken while following the Maximum Metabolism Weight Loss Plan™ enclosed in every bottle.
Enjoying good food is part of a healthy lifestyle, but too often we don’t know when to stop. PineSlim can help by addressing one of the most basic of the dozen deep metabolic systems identified by Source Naturals as critical to your optimal health: Hormones/Metabolism.
Less Calories for Improved Health
According to a National Health and Nutrition Examination Survey, an estimated 66% of U.S. adults are overweight. A normal body fat level is one of the factors associated with many markers of good health, including insulin efficiency, healthy inflammation response, good circulation, and normal cell regeneration. One of the best ways to achieve healthy weight is by curbing the amount of calories we take in—but that’s not always easy to do. Now an ancient Asian food source may help.
Korean Pine Nuts—Traditional Asian Food
The Korean pine nut (Pinus koraiensis) has been used as a food source for centuries and is often served as a snack at social events in China. Korean pine nuts grow on evergreen trees that produce seeds (commonly referred to as nuts) that are rich in oil, particularly oleic, linoleic, and pinolenic acids.
Pinolenic acid is a fatty acid, which may influence healthy blood pressure. According to recent research, pinolenic acid also may increase concentrations of the satiety hormones glucogon-like peptide-1 (GLP- 1) and cholecystokinin (CCK).
Both GLP-1 and CCK are hormones that have been found to increase satiety and suppress appetite in normal-weight humans. They are believed to work by delaying gastric emptying. Retaining food in the stomach for a longer period of time may prolong a feeling of fullness.
In a randomized, double-blind trial, 18 overweight women received 3.00 grams of Korean pine nut oil (PinnoThin™)—the same amount as one daily dose of Pine Slim—or an olive oil placebo before a carbohydrate meal. Hormone measures of CCK and GLP-1 were taken from blood samples, and subjective measures of appetite were recorded. The study demonstrated a significant increase in appetite-suppressing CCK and GLP-1 hormones at 30-60 minutes after supplementation.
Your Source for Advanced Nutrition
The plant world offers an abundance of health promoting compounds. Today exciting discoveries are emerging from research into the health benefits of botanicals. The development of PineSlim reflects Source Naturals’ commitment to manufacturing supplements on the cutting edge of nutritional science. We are glad to partner with your local health food store in bringing you nutritional resources that help you take charge of your health.
Causey JL (3/28/06) Korean Pine Nut Fatty Acids Induce Satiety-producing Hormone Release in Overweight Human Volunteers, American Chemical Society Abstract, “Health Benefits of Lipids” Symposium. ABSTRACT 0117: TECH-3.
Fontana L. (2006) Excessive Adiposity, Calorie Restriction, and Aging. JAMA. 295(13): 1577-1578. Masoro EJ. (2005) Overview of caloric restriction and ageing. Mech Ageing Dev. 126: 913-922. Sugano M, Ikeda I, Wakamatse K, Oka T. (1994)
Influence of Korean pine (Pinus koraiensis)-seed oil containing cis-5,cis-9,cis-12-octadecatrienoic acid on polyunsaturated fatty acid metabolism, eicosanoid production and blood pressure of rats. British Journal of Nutrition. 72:775-783.
How to Manage Migraines Naturally: Magnesium - Feverfew - Butterbur - Ginger
December 21, 2007 10:41 AM
Before you can understand how to manage migraines naturally, it is necessary to understand exactly what they are and how certain treatments could work. It is not generally known that the word ‘migraine’ means ‘half the head’ because it frequently hurts only on the right or the left of the head of sufferer. Some people with migraines do feel pain on both sides at once, although this is not generally the case.
A migraine occurs in stages which are activated by fluctuations in the hormone content of the blood. The ‘aura’, when you see spots and flashing lights in front of your eyes, is the first stage of a migraine attack, and during this time the blood vessels in your neck and head are contracting. You could also find it difficult to concentrate and your fingers could feel cold. At this point they do not have the headache that starts when the blood vessels begin to dilate.
Rather than the contracted blood vessels slowly returning to normal, your hormones have an excessively strong reaction, and cause them to dilate rapidly and become much wider than they should be leading to a severe headache due to pressure on the nerves. Different hormones can be involves with each attack, and the range of effective natural treatments reflect this fact. During this period, your brain could swell slightly, your muscles can tense up and other things can happen to the chemical and hormonal balance of your body. That is why some herbal treatments work for some but not for others, and different people find different treatments effective for them. What works for you might not work for somebody else if their migraine has a different cause. Basically, though, migraines occur in two phases, one being associated with an excess of hormones and the other with a shortage.
It is not easy to live with a migraine since it can be completely debilitating. Some just have a severe headache, while others are affected for days at a time. The headache can become before and after the onset of the shimmering lights and other optical effects that are generated by the brain. It would certainly be useful if those prone to migraines had one or more of the possible natural remedies to hand since there is rarely time to seek to seek professional medical help once the migraine begins, and through the use of natural remedies a potentially bad attack could be nipped in the bud, and at least its effect on you reduced.
Magnesium is common in green leafy vegetables such as spinach and cabbage, whole grains, nuts and seeds. It is an essential mineral for human biochemistry, and is also needed with calcium for healthy bone development and maintenance.
Magnesium is a muscle relaxant, and relaxes the muscles of the blood vessels helping them to relax their dilatancy that cause the migraine pain. It is also useful to help the immune function, reduces blood pressure (by the same blood vessel relaxing mechanism) and also the rhythm of your heart. Magnesium therefore provides you with many health benefits, and though the western diet is not generally deficient in magnesium, some areas can be and a magnesium-containing supplement will not do you harm.
However, particularly high dose of magnesium can lead to nausea, diarrhea, low blood pressure and many other unpleasant side effects, so do not take more than the RDA (recommended daily allowance) in your supplement. Many studies have confirmed its effectiveness in reducing the symptoms of migraine, but not all studies have been successful. However, the condition is so debilitating to so many people, that it should be tried although not in excess. Make sure, however, that your doctor is informed since it could interfere with other medication you are taking for your migraine.
Riboflavin, vitamin B-2, is also believed to useful in reducing the duration and frequency of migraine attacks, working in much the same way as magnesium. It is known that there are many cases of people who suffer from vitamin B-2 deficiency also suffering from migraines, and a riboflavin supplement is also worth trying if you are a consistent victim of this condition.
Feverfew is the best known of the herbal remedies for migraine, and has been used for centuries in the treatment of fevers, headache, migraine and other painful conditions such as arthritis. The active ingredient is parthenolide, an anti-inflammatory that is also an anti-hyperalgesic, and that would explain its effect on reducing the pain. It also blocks lipolysaccharide-induced osteolysis by suppressing the activity of a eukaryotic transcription factor protein known as NF-kappaB that can cause a number of immune response problems, including inflammatory conditions such as arthritis, hence its use to relieve that condition.
Its effect on migraines could be explained by this activity in repressing the inflammatory response to certain stimuli that could be brought about by hormonal activity. Because it must be taken for a few weeks before the actual problem arises in order to be effective against it, feverfew is not effective to treat an existing attack, but to prevent future attacks. Double blind studies have proved its effectiveness in many tests, but not in all. However, if you take feverfew as a regular supplement in you diet, you might never have to try magnesium or vitamin B-2 supplements.
Some people swear by the leaves of feverfew, eating one per day which is easy way to take it. It is important, however, that you do so regularly, since it can take for up to 6 – 8 weeks for you to notice a reduction in your attacks. Don’t give up after 5 or 6 weeks, but continue, since the results will be well worth it. If you stop for a week or two you will have to start all over again. You might get a sore mouth and perhaps mouth ulcers to start with, but these will eventually go once your body is used to it.
You are probably best not to take if you are pregnant since it could cause you to abort. Otherwise, however, it has been shown to be effective in many severe cases. Feverfew is bitter, and can be used as a tea with other herbs, such as rosemary, lavender and sage. If you are taking warfarin, aspirin or other blood-thinning drugs, see your doctor first, and the same is true of NSAIDs (non-steroidal anti-inflammatory drugs). If you are taking these for arthritis, the feverfew itself might be more effective!
If you are taking feverfew as a supplement using commercially available dried leaf then the recommended dosage is around 125mg of the dried leaf. It should contain at least 0.2% of parthenolide (0.25mg/daily), although other studies have indicated that a total of 0.7 mg parthenolide a day should be taken (100mg at 0.7%). Parthenolide is unstable so don’t take it after its sell by or best by date.
Butterbur is also useful in the treatment of migraines. The active ingredient here is petasin, a sesquiterpene ester that also has anti-inflammatory properties, all though it works in a different manner to feverfew. Here, it inhibits the activities of leukotriene generation in neutrophils and eosinophils, which indicates that it also possesses anti-allergenic properties that could help asthmatics that also suffer from migraines. It does not prevent the release of histamine, but does appear to reduce smooth muscle spasm.
You should never take the raw herb, only the extract, because it contains alkaloids that can harm you. The butterbur extract, however, is a perfectly safe supplement and found effective by many people in the treatment of migraine.
If your migraine is at the front of the head, then you should try ginger. Unlike feverfew, ginger works on a migraine as it is occurring, and improvement can be achieved for a bad migraine within half an hour. In fact if, like many people, you can feel a migraine coming on, half a teaspoon of freshly ground ginger can stop the pain before it starts.
Many herbal treatments for migraine include a combination of some of the above remedies, and many people swear by them. However, migraine treatment is very personal, and you should use what works best for you. If you are also taking other medical treatments however, please make sure that you refer to your physician before using any others, and that includes herbal remedies or supplements.
This sour Indian fruit can have a sweet appetite-stifling effect
May 26, 2007 05:44 PM
Stay satisfied with garcinia
This sour Indian fruit can have a sweet appetite-stifling effect.
It’s funny how modern science continues to support ancient systems of herbal healing. Such is the case with garcinia: the yellowish, pumpkin like fruit of the Garcinia cambogia tree, log valued in tropical Asian cooking for its sweetly acidic taste, is a traditional Indian remedy for digestive problems that is also used to make meals more filling. Today, garcinia (also known as brindleberry and Malabar tamarind) is used in natural weight-loss products based on research supporting its stomach satiating powers. Scientists also believe that garcinia helps block fat formation and regulate glucose (blood sugar) usage vital functions in an increasingly overweight world.
Filling up Faster
One reason so many people losing the battle of the bulge is that temptations to eat – and eat – are absolutely everywhere, often as the focal points of clever and well designed advertising campaigns. (Remember the slogan “belch’a can’t eat just one”?) To make matters worse, restaurants often serve overly generous portions and experiments have shown that the more food you serve, the more people will consume. For example,
The answer would seem simple – just eat less. But knowing when to say when isn’t easy. That’s where garcinia comes in, specifically an extract taken from the rind called HCA (Hydroxycitric acid). In laboratory animals HCA has upped levels of serotonin, a brain chemical that helps suppress appetite and elevate mood, which might help take the edge off the depressing and binge-eating urges that often affect would-be weight losers. At the same time HCA appears to reduce levels of another substance in the brain called neuropeptide Y, which enhances appetite (Experimental Biology meeting 4/06).
What is it: the pumpkin-like fruit of the garcinia cambogia tree; this Indian native is used in cooking and in Ayurveda, the country’s system of traditional medicine.
What is does: A popular ingredient in natural weight-loss aids, garcinia is being investigated for possible fat blocking and appetite-suppressing functions; it may also help regulate glucose (blood sugar).
Fat Smack down
The fat that stubbornly clings to your frame doesn’t always start out that way. In many cases, your body actually creates fat from excess carbohydrates (such as the icing encrusted doughnut you couldn’t pass u at breakfast). If you don’t burn off those extra carbs through exercise, they are broken down into citrates that are then transformed into the building blocks of body fat. This process is controlled by an enzyme called citrate lyase; HCA interferes with this crucial enzyme, an action that inhibits fat formation. Researchers believe the body uses those extra carbs to provide more energy; this mechanism may also have the happy side effect of further checking appetite. In addition, results from a Dutch lab study indicate that garcinia may blunt sugar-induced increases in glucose, which can help forestall diabetes development.
Garcinia works best when teamed with out nutrients and herbs, such as chromium, green tea and forskolin. In one investigation, over weight people who stuck to a supervised diet and exercise program supplemented with a combination of HCA, chromium and another herb called Gymnema lost body weight and mass, and showed improved fat burning capacity (Nutrition Research 1/04). This modern usage mirrors Ayurveda’s ancient precepts, according to which individual remedies are generally used in combination for more effective results. Looking to get your meals more staying power? Then look for garcinia in your favorite weight loss formula. –Lisa James
This is sour Indian fruit can have a sweet appetite stifling effect.
January 13, 2007 02:44 PM
It’s funny how modern science continues to support ancient systems of herbal healing. Such is the case with Garcinia: The yellowish, pumpkin like fruit of the Garcinia Cambodia tree, long valued in tropical Asian cooking for its sweetly acidic taste, is a traditional Indian remedy for digestive problems that is also used to make meals more filling. Today, Garcinia (also known as brindleberry and Malabar tamarind) is used in natural weight-loss products based on research supporting its stomach satiating powers. Scientists also believe that Garcinia helps block fat formation and regulate glucose (blood sugar) usage—vital functions in an increasingly overweight world.
Filling Up Faster
One reason so many people are losing the battle of the bulge is that temptations to eat-and eat—are absolutely everywhere, often as the focal points of clever and well designed advertising campaigns. (Remember the slogan “belch’a can’t eat just one”?) To make matters worse, restaurants often server overly generous portions and experiments have shown that the more food you serve, the more people will consume. For example, Chicago moviegoers ate 45% more popcorn from larger containers even when they were given stale product (Food Quality and Preference 1/01).
The answer would seem simple—just eat less. But knowing when to say when isn’t easy. That’s where garcinia comes in, specifically an extract taken from the rind called HCA (Hydroxycitric acid). In laboratory animals HCA has upped levels of serotonin, a brain chemical that helps suppress appetite and elevate mood, which might help take the edge off the depression and binge-eating urges that often affect would-be weight losers. At the same time HCA appears to reduce levels of another substance in the brain called neuropeptide Y, which enhances appetite (Experimental Biology meeting 4/06).
What it is: the pumpkin-like fruit of the Garcinia cambogia tree; this Indian native is used in cooking and in Ayurveda, that country’s system of traditional medicine
What it Does: A popular ingredient in natural weight-loss aids, garcinia is being investigated for possible fat blocking and appetite suppressing functions; it may also help regulate glucose (blood sugar).
The fat that stubbornly clings to your frame doesn’t always start out that way. In many cases, your body actually creates fat from excess carbohydrates (such as the icing encrusted doughnut you couldn’t pass up at breakfast). If you don’t burn off those extra carbs through exercise, they are broken down into citrates that are then transformed into the building blocks of body fat. This process is controlled by an enzyme called citrate lyase; HCA interferes with this crucial enzyme, an action that inhibits fat formation. Researchers believe the body uses those extra carbs to provide more energy; this mechanism may also have the happy side effect of further checking appetite. In addition, results from a Dutch lab study indicate that garcinia may blunt sugar-induced increases in glucose, which can help forestall diabetes development.
Garcinia works best when teamed with other nutrients and herbs, such as chromium, green tea and forskolin. In one investigation, overweight people who stuck to a supervised diet and exercise program supplemented with a combination of HCA, chromium and another herb called Gymnema lost body weight as mass, and showed improved fat burning capacity (Nutrition Research 1/04). This modern usage mirrors Ayurveda’s ancient precepts, according to which individual remedies are generally used in combination for more effective results.
Looking to give your meal more staying power? Then look for garcinia in your favorite weight loss formula. –Lisa James.
7-Syndrom Healing and 5-HTP
June 07, 2006 03:49 PM
Boomer Breakthrough – Keeping in the Game
If there is not thing boomers need to manage, its chronic stress. That’s because of its deleterious effects, which include accelerated aging and altered brain function. This month boomer breakthroughs will focus on 5-hydroxytryptophan or 5-htp, one of the most versatile and powerful anti-aging remedies. For starters, 5-htp is a more powerful antioxidant than either vitamin C or melatonin. This it deserves a place in ones daily vitamin regimen based on this fact alone. However, the better-known attribute of 5-htp is its stabilizing effects on the brain and nerves.
Mood, Anxiety and Depression
Chronic stress can lead to mood swings, anxiety, depression, poor memory, and reduced cognitive functions. Last month we recommended the Adaptogenic herbs Ashwagandha and Rhodiola as therapy for smoothing out periods of intense stress such as looming deadlines. For longer term stress supplementation with 5-htp is a better choice. That’s because extended periods of stress reduce brain levels of serotonin. Supplemental 5-htp is produced from the African plant Griffonia Simplicifolia and has over 30 years of safety and effectiveness in clinical use.
How do you know if you have low levels of serotonin? Persistent anxiety is one key and insomnia is another. 5-htp, an intermediary metabolite of serotonin, has proven to be clinically effective in reducing these disorders. Weight gain and eating disorders also appear to be associated with low serotonin levels.
Serotonin the Antiaging Neurotransmitter
Serotonin, one of three major neurotransmitters, has a calming effect and helps keep emotions in check. It has been extremely helpful in lessening panic attacks, various phobias, suppressing appetite, and reducing aggression, anxiety, and pain sensation. And, it may be more effective in relieving mild depression than antidepressants. In a 1991 Swiss study, the effectiveness of 5-htp in alleviating depression was compared to a conventional antidepressant, fluvoxamine (Luvox). Patients were divided into two groups and given either 100mg 5-htp or 150mg of fluvoxamine three times a day for six weeks. At the end of the test period, the 36 5-htp patients showed a greater percentage of improvement than the 33 fluvoxamine patients.
Other studies have compared 5-htp with antidepressants such as chloripramine and imipramine. 5-htp was at least as effective if not more so than the conventional drugs. Moreover, 5-htp has no reported side effects, although some patients have experienced mild nausea when they first take 5-htp. If this happens, merely back off and reduce the daily dose to 50mg and gradually increase it over a four-day period.
5-htp has an advantage over its precursor amino acid L-Tryptophan (LT). it is more readily absorbed than LT and is immune to meals without reducing its effectiveness. 5-htp, unlike LT, is not shunted into niacin, melatonin, picolonic acid and other amino acids. Seventy percent of oral 5-htp ends up in the bloodstream, crosses into the brain and is directly converted into serotonin.
It’s best not to combine 5-htp with antidepressant medications, although there have been no reports of adverse events. Suggested doses is 100mg 3 times a day or 200 to 200 mg taken at bedtime for insomnia.
Pain, Per-menopause and PMS
5-htp has additional benefits for boomers. It reduces hot flashes and is an effective anti-pain remedy. The concern over use of hormone replacement therapy (HRT) has led to interest in safe and effective methods of reducing hot flashes. Come anti-depressants (Prozac, ect.) have been effective in alleviating hot flashes in women with breast cancer or at risk of the disease. Increasing serotonin is the proposed mechanism by which this occurs. Serotonin in turn resets the brain’s heat regulating system. 5-htp is effective at raising serotonin levels, is free of side effects, and is an effective substitute for anti-depressants.
Additionally, 5-htp has been clinically useful in reducing premenstrual dysphoric disorder (PMDD) symptoms such as sadness, hopelessness, self-deprecation, tension, anxiety, emotional instability, tearfulness, anger and irritability.
Migraine and fibromyalgia share a common root in serotonin and adrenal hormone (Cortisol) receptor function. Serotonin plays a role in maintaining pain thresholds, vascular constriction/dilation and maintenance of restorative sleep. It is also thought to disrupt pain signals and induce the activity of endorphins, the brains natural painkiller.
Italian researchers report in two clinical trials involving patients with fibromyalgia, that 5-htp (100mg 3X/day) significantly reduced fibromyalgia symptoms. These include a number of tender points, subjective pain severity, morning stiffness, sleep patterns, and anxiety.
Now offers 5-htp in three convenient doses; 50mg for starters, 100mg for maintenance, and 200mg plus 250mg tyrosine, Niacinamide and vitamin B-6 to stabilize adrenal function and help control minor pain.
Adapted from 7-syndrome healing: Supplement essentials for Body and Mind by Marcia Zimmerman and Jayson Kroner, 2006, Nutrition Solution Publications.
Phosphatidyl Serine - HEALTHY COGNITION BRAIN FUNCTION
December 21, 2005 11:04 AM
“To the dull mind, nature is leaden. To the illumined mind, the whole world burns and sparkles with light.” Ralph Waldo Emerson
From the moment we rise to the moment we rest, our brain is in a decision-making frenzy. When we’re thirsty, our brain tells us that we need water. When we’re hungry, it reminds us that we have a refrigerator full of food. When we’re tired, it lets us know that we need to sleep, and so on. But despite the thousands of decisions we make everyday, our brain still hasn’t figured out a way to let us know what it needs to func¬tion.
Though ironic, this raises a very serious issue. The human brain, like every other organ in the body, demands nutrition - period. Unfortunately, it leaves that up to us to figure out. Thanks to notable advance¬ments in research, we’re finally learning which nutri¬ents are most important for optimal brain function. Phosphatidyl Serine (PS) is a perfect example. This naturally occurring phospholipid has been the subject of numerous studies regarding its ability to boost cognitive function and delay (or potentially reverse) memory deterioration, and suggests that PS may be able to increase the effectiveness of neural transmissions. Interestingly, PS accounts for roughly 15% of the brain’s phospholipid supply. This is enor¬mous because phospholipids play a significant role in the billions of neurotransmissions that take place every second. Yes, billions.
Brain cells are constantly communicating with one another, and send astonishing amounts of impulses throughout the nervous system. This is accomplished via neurotransmitters - chemical messengers that send and receive impulses over the synapses of the brain and throughout the body. Mentally, we’re function¬ing at our best when these cells are well nourished. We can think more clearly, recall memories with ease and operate with greater efficiency. However, a de¬ficiency in neural-nutrients can prevent these mind messengers from functioning as they should. For¬tunately, PS has the ability to cross the blood-brain barrier to deliver critical nutrients and remove mind-slowing waste.
Consider this. The brain functions in the same man¬ner that a major airport does around the holidays. There are millions of actions taking place. Impulses departing, nutrients arriving, endless communication, the occasional problem and more reactions than any¬one could possibly count. There’s confusion, delay and emotion, not to mention the endless series of transmissions that take place every second. Imagine PS as that ultra-motivated employee who shows up to work everyday anxious to expedite everything in sight. It helps neural travelers get to and from their respec¬tive gates, ensures that they have everything they need, simplifies processes that could result in breakdown, and clears isles that are cluttered with junk. Simply stated, PS is the brain’s overachieving go-getter.
PS can help us think more clearly.
It’s 3:06 in the afternoon and you’re scrambling to get to a meeting that you’re already late for. That fluster could be the result of poor neurotransmission caused by a deficiency in essential nutrients like PS. Moreover, these innocent brain-bursts can exhaust our PS reserves, leaving us somewhere hovering be¬tween frantic and sluggish. Every impulse, thought, action, reaction, movement, emotion and desire is the end result of neurotransmitters in action. PS is a major supporter of these actions. Therefore, as we increase the amount of PS in our system, we gain the ability to think and act with greater ease.
PS can reduce the adverse impacts of stress on our body and mind.
What do we do when we’re down in the dumps? While plopping down on the sofa with a snack might be an easy solution, it comes with a price. Not only does stress interfere with mood, but it can also inspire inactivity, over-eating and sluggishness. This is due largely in part to cortisol - a catabolic hormone released by the adrenal glands in response to emotional stress. Studies done to determine the effectiveness of PS on cortisol suppression have shown that it works by suppressing the hormones that produce cortisol. As a result, supplementing with PS may be able to help reduce the amount of stress related hormones that ultimately leave us singing the blues.
PS can expedite post workout recovery time.
Endurance athletes who carefully monitor their body’s response levels are increasingly turning to PS. Immediately following strenuous activity, the body responds by releasing adrenocorticotropin (ACTH) – a hormone that discourages testosterone and encourages cortisol. By limiting ACTH pro¬duction, PS reduces the amount of muscle tissue breakdown that occurs during exercise. A common misconception is that muscles grow during exercise - wrong. In fact, muscles are torn down during ex¬ercise and grow in-between workouts – hence the term recovery. During recovery, PS helps prevent the activity of growth-inhibiting hormones. This helps athletes recover faster so their gains are realized more quickly.
In short, Phosphatidyl Serine appears to be a completely safe and beneficial dietary supple¬ment that can offer a wide range of physical and mental health benefits. NOW® Phosphatidyl Serine is derived from soy leci¬thin, and includes Choline and Inositol – two metabolites that work synergistically to help in¬crease circulation and cognitive response.
Preventing Chronic Health Problems with AHCC
October 26, 2005 05:57 PM
Preventing Chronic Health Problems with AHCC
In a country supposedly as healthy as ours, an estimated 175 million people suffer from one form of chronic imbalance or another. This can take the form of obesity, which is the second leading cause of preventable death in the United States, second only to cigarette smoking; challenges to heart health, blood pressure, blood glucose levels, joint and cell health ,to name just a few.
In fact ,treating chronic health problems is what modern medicine has become .Sure, there are still many acute illnesses treated by modern medicine; but for the most part, we are fortunate enough to have long life spans and the health issues that go along with it. Therefore it is important to make sure that out immune systems are up to the task. That is where AHCC should become part of our daily lives.
AHCC is an nutritional supplement that was developed and is manufactured solely in Japan under strict practices. It is a hybridized extract of medicinal mushrooms where the active ingredient is an oligosaccharide made from the mycelia of several species of mushrooms, grown in rice bran.
AHCC and Cell Senescence
Every few years, a new buzz word comes along in medical circles. The latest one to be used both in a positive and negative fashion is senescence. For example, if an unhealthy cell can be artificially made to senesce, or grow old, then it will die sooner. If senescence of healthy cells can be delayed, that is an amazing achievement.
AHCC is the first nutritional supplement that shows principles of being able to promote certain cells in the immune system that keep us young and healthy, thus delaying immunosenesnscence.
AHCC and the Immune System
In order to get a full appreciation of how important taking AHCC on a daily bases is, one needs to understand the intimate role the immune system plays in our daily lives. It is responsible for riding our bodies of the unhealthy cells that are produced every day. The immune system protects us from the polluted air we breathe, the chemicaalized foods we eat, and most importantly, from the stress we bring upon ourselves just by the very nature of the way we live our lives. Our bodies were made for flight or fight capability; but never in history have we been in that mode on a daily basis. Our immune systems are under constant assault and it is up to you to take care of it even though you may not even be aware that it is there. We tend to only to think of our immune system when it is not working-when suffer mild or severe health challenges.
Without getting into too much detail, our immune system is a complex series of cells that all communicate with each other and must be balanced correctly in order for us to stay healthy. AHCC is able to encourage the helpful cells such as the natural killer (NK) cells while suppressing the ones that foster problems.
I am in clinical practice on a daily basis and use AHCC in almost every one of my patients. It is very versatile because of its effects on the immune system.
A Company Committed to Excellence
If everything I just told you wasn’t enough to convince you that AHCC should become part of your daily armamentarium, then here’s more fuel. AHCC is produced by a chemical company that is committed to excellence in manufacturing and most importantly in research. They have supported research at hospitals around the world, including local ones such as Columbia University, Harvard University and the University of California.
In fact, I just returned from a trip to Sapporo, Japan where the product is made and where each year, a team of scientists and medical professionals gather to discuss the latest research on AHCC, GCP, and oliganol-all products made by the same company. This was the 13th annual symposium and was attended by close to 1000 professionals.
It is remarkable to me that this company is able to produce such well-documented research while still being a nutritional supplement company, which shows it can be done. To me, this is the sign of a nutritional supplement worth recommending. If it does what it says it is supposed to do and has research to support those claims, than that is something you want in your daily diet.
So, even though you may never have given your immune system a second thought, you really should; and the best way to help it out is by taking AHCC on a daily basis, just like I do. I recommend 500 mg per day in the summer months and 1500 per day in the winter months as a simple preventive. Stay healthy!
About the Author
Fred Pescator, M.D., a traditionally trained physician practicing nutritional medicine, is President of the AHCC Research Association. He is the author of The Hamptons’ Diet, Thin For Good and Feed Your Kids Well. Dr.Pescator lectures around the world, and has been featured on such shows as The View, The Today Show, Deborah Norville, The O’ Reilly Factor, and Extra. Recent interviews include Woman’s Health and Fitness, Let’s Live, the New York Times, the Wall Street Journal, Fortune and more. He is also the author of numerous papers and magazine articals. Dr.Pescator is actively involved in clinical research , and is instrumental in developing and clinically testing many of the leading nutritional products. He is the President-Elect of the International and American Association of Clinical Nutritionists and a member of the National Association of Physician Broadcasters.
The above article is for informational purposes only and is not intended to diagnose or treat a particular illness. The reader is encouraged to seek the advice of a holistically competent licensed professional health care provider. The information in this article has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
The Essential Woman Formula
August 15, 2005 12:11 PM
The Essential Woman Formula
-Organic Unrefined Flaxseed Oil
The primary ingredient in The Essential Woman is unrefined organic flaxseed oil, the world’s richest source of essential fatty acids. These important nutrients, alpha linolenic acid (omega 3) and linoleic acid (omega 6) have been shown in scientific studies to benefit over 60 health conditions. Since these vital nutrients are classified as essential, they are absolutely necessary to maintain good health. Several of the most important benefits of essential fatty acid rich flaxseed oil include normalizing cholesterol and triglyceride levels, suppressing inflammation and allergies, alleviating depression, combating fatigue and beautification and healing of the skin. When it comes to these vital nutrients The Essential Woman is exactly that, essential!
-Evening Primrose Oil
Evening Primrose Oil is an integral part of The Essential Woman product for a very important reason. This proven and popular nutritional oil provides a source of specialized nutrient known as gamma linolenic acid or GLA. Volumes of scientific studies support the use of GLA for a woman’s unique requirements. GLA helps balance hormone like substances which, when out of balance, can lead to distressing symptoms of premenstrual syndrome. The Essential Woman was carefully formulated to provide optimal levels of GLA while working in concert with the other nutrient actives in the product.
Lignans are a class of plant phytonutrients that are concentrated in the solid portion of the flaxseed. These amazing compounds have shown such extraordinary potential that they have been studied by the National Cancer Institute for their cancer preventative properties. Lignans act as estrogen modulators, balancing human estrogen with both weak estrogenic and anti-estrogenic activity. This helps maintain a regulating activity on human estrogen which has been implicated as a factor in both breast and colon cancers. This is a particular concern for women as estrogen levels rise just prior to and during menopause. Lignans are yet another nutritional ally found in The Essential Woman necessary to meet the special demands of today’s woman.
The simple soybean is a power house of nutritional factors. The much researched isoflavones in soy belong to a family of compounds known as bioflavonoids. The isoflavones in The Essential Woman are concentrated to provide optimal levels in every tablespoon. Scientific studies on isoflavones reveal an astounding array of nutritional benefits for women. Most notably are its effects on bone health and menopause. Researchers have found isoflavones effective in the prevention of bone loss and conclude that isoflavones are an effective natural means to help prevent osteoporosis and provide bone strengthening support. Soy isoflavones area also classified as plant phytoestrogens which are more delicate in their actions than the actual human estrogen, but target human cells in the same manner. In this way, isoflavones are believed to be able to block the overstimulation of human estrogens much like the plant lignans discussed earlier. This is good news for women entering their menopausal phase of life. Isoflavones of phytoestrogens can help alleviate the annoying symptoms of menopause and PMS as well as help reduce the risk of fragile bones, heart disease, breast and other cancers. As more and more women take charge of their personal health and well being, the need for a comprehensive nutritional support system is vital. The Essential Woman provides a formula for success designed for the special needs of a woman’s body.
July 25, 2005 10:14 PM
An ovarian cyst usually forms when follicles in the ovary fail to normally develop and subsequent release from the ovary is impaired in some way. As a result of this abnormality, hormonal balance is disrupted with typical estrogen surges resulting in the formation of a growing cyst either from the follicle or from the corpus luteum. Consider the following quote concerning cysts: Natural progesterone, given from day 5 to day 26 of the menstrual month for 2-3 cycles, will almost routinely cause the cyst to disappear by suppressing normal FSH, LH and estrogen production, giving the ovary time to heal. 19
The Role of Naturally Occurring Progesterone in the Body
July 25, 2005 09:50 PM
The Role of Naturally Occurring Progesterone in the Body
In light of the previous section, it is vital to keep in mind that when progesterone is produced and maintained, most of the negative side effects of estrogen are neutralized. Unfortunately, in far too many women, progesterone levels fail to do the job. Let’s discuss exactly what progesterone is responsible for.
A woman’s ovaries produce two key hormones: estrogen and progesterone during her ovulatory years. The corpus luteum makes progesterone just before ovulation which rapidly escalates during the two week period following ovulation. The primary task of progesterone is to support implantation and sustain pregnancy. It does this by inhibiting uterine contraction and by suppressing the immune system’s response to the developing embryo as a foreign body.2
During the last two weeks of a woman’s menstrual cycle, progesterone is considered the dominant female hormone. During pregnancy, the placenta takes over the task of progesterone synthesis. Progesterone is also made in limited amounts in the adrenal glands of both men and women and in the testes of the male.
PROGESTERONE SECRETION RATES
The following breakdown gives general guidelines of amounts and time of progesterone secretion:
Approximately twelve days following ovulation, if fertilization has not occurred, progesterone levels decline rapidly, which initiates the shedding of the uterine lining, also known as menstruation.
In time, progesterone is transported through the bloodstream to the liver where it is metabolized and excreted as waste through the kidneys (urine) and the bile. Typically, pregnancy tests are reacting to increased levels of HCG or of progesterone in the urine, indicating that pregnancy has occurred. (Note: What is crucial to remember is that a woman’s cycle, regardless of her age, may not be characterized by the above scale. A number of factors may cause estrogen to remain dominant, even after progesterone is supposed to take over in the latter half of the cycle. Even young women who suffer from nutritional deficiencies, stress, etc. may experience an estrogen dominance, suggesting the need for natural progesterone supplementation.)
THE THREE-FOLD ACTION OF PROGESTERONE
1. It ensures the implantation and development of a fertilized egg and subsequent embryo and fetus.
2. It acts as a precursor to other steroid hormones such as cortisone which is produced in the adrenal glands and contributes to the production of the sex hormones including testosterone.
3. It exerts a number of desirable physiological actions.
Pain - Post Op and Relaxation
July 13, 2005 09:24 AM
Relaxation, Music Reduce Post-Op Pain. New research has found that relaxation and music, separately or together, significantly reduce patients' pain following major abdominal surgery. The study, published in the May issue of the journal Pain, found that these methods reduce pain more than pain medication alone. Led by Marion Good, PhD, RN, of Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, Ohio, the study is supported by the National Institute of Nursing Research (NINR), at the National Institutes of Health. "This is important news for the millions of Americans who undergo surgery and experience postoperative pain each year," said Dr. Patricia A. Grady, director of the NINR.
"Better pain management can reduce hospital stays and speed recovery, ultimately improving patients' quality of life." Dr. Good and her research team studied three groups of patients undergoing abdominal surgery. In addition to the usual pain medication, one group used a jaw relaxation technique, another group listened to music, and a third group received a combination of relaxation and music.
Findings revealed that, after surgery, the three treatment groups had significantly less pain than the control group, which received only pain medication. "Both medication and self-care methods which involve patient participation are needed for relief," said Dr. Good.
"These relaxation and music self-care methods provide more complete relief without the undesired side effects of some pain medications." The findings have important implications for the 23 million people who undergo surgery and experience postoperative pain annually in the United States. Pain can hamper recovery by heightening the body's response to the stress of surgery and increasing tissue breakdown, coagulation and fluid retention. Pain also interferes with appetite and sleep and can lead to complications that prolong hospitalization.
Dr. Good and her research staff worked with 500 patients aged 18-70, who were undergoing gynecological, gastrointestinal, exploratory or urinary surgery. Prior to surgery, those in the music, relaxation or combination groups practiced the techniques. The relaxation technique consisted of letting the lower jaw drop slightly, softening the lips, resting the tongue in the bottom of the mouth, and breathing slowly and rhythmically with a three-rhythm pattern of inhale, exhale and rest. Patients in the music group chose one of five kinds of soothing music--harp, piano, synthesizer, orchestral or slow jazz.
On the first and second days after surgery, all patients received morphine or Demerol for pain relief by pressing a button connected to their intravenous patient controlled analgesia pumps. The groups receiving the additional intervention used earphones to listen to music and relaxation tapes during walking and rest, while the control group did not. The research team measured the patients' pain before and after 15 minutes of bed rest and four times during walking to see if the sensation and distress of pain changed.
Dr. Good found that during these two days postsurgery the three treatment groups had significantly less pain than the control group during both walking and rest. "Patients can take more control of their postoperative pain using these self-care methods," says Dr. Good. "Nurses and physicians preparing patients for surgery and caring for them afterwards should encourage patients to use relaxation and music to enhance the effectiveness of pain medication and hasten recovery."
Dr. Good's findings have implications for future research into the effectiveness of self-care methods on other types of pain, including chronic pain, cancer pain, and pain of the critically ill.
Vitamin D Lack Linked to Hip Fracture. Vitamin D deficiency in post-menopausal women is associated with increased risk of hip fracture, according to investigators at Brigham and Women's Hospital in Boston, Mass. In a group of women with osteoporosis hospitalized for hip fracture, 50 percent were found to have a previously undetected vitamin D deficiency. In the control group, women who had not suffered a hip fracture but who were hospitalized for an elective hip replacement, only a very small percentage had vitamin D deficiency, although one-fourth of those women also had osteoporosis. These findings were reported in the April 28, 1999, issue of the Journal of the American Medical Association.
The study, conducted by Meryl S. LeBoff, MD; Lynn Kohlmeier, MD; Shelley Hurwitz, PhD; Jennifer Franklin, BA; John Wright, MD; and Julie Glowacki, PhD; of the Endocrine Hypertension Division, Department of Internal Medicine, and Department of Orthopedic Surgery, Brigham and Women's Hospital, Boston, was supported by grants from the National Institute on Aging (NIA) and the National Center for Research Resources (NCRR. These investigators studied women admitted to either Brigham and Women's Hospital or the New England Baptist Hospital, both in Boston, between January 1995 and June 1998.
A group of 98 postmenopausal women who normally reside in their own homes were chosen for the study. Women with bone deterioration from other causes were excluded from the study.
There were 30 women with hip fractures caused by osteoporosis and 68 hospitalized for elective joint replacement. Of these 68, 17 women also had osteoporosis as determined by the World Health Organization bone density criteria. All the participants answered questions regarding their lifestyle, reproductive history, calcium in their diet, and physical activity.
Bone mineral density of the spine, hip, and total body were measured by dual X-ray absorptiometry (DXA) technique, as was body composition. Blood chemistry and urinary calcium levels were analyzed. The two groups of women with osteoporosis did not differ significantly in either time since menopause or bone density in the spine or hip. They did, however, differ in total bone density.
The women admitted for a hip fracture had fewer hours of exercise than the control group. Fifty percent of the women with hip fractures were deficient in vitamin D, 36.7 percent had elevated parathyroid hormone (PTH) levels (a hormone which can stimulate loss of calcium from bone), and 81.8 percent had calcium in their urine, suggesting inappropriate calcium loss. Blood levels of calcium were lower in the women with hip fractures than in either elective group.
These researchers propose that vitamin D supplementation at the time of fracture may speed up recovery and reduce risk of fracture in the future. Current Dietary Reference Intake Guidelines contain a daily recommendation of 400 IU of vitamin D for people aged 51 through 70 and 600 IU for those over age 70.
"We know that a calcium-rich diet and regular weight-bearing exercise can help prevent osteoporosis. This new research suggests that an adequate intake of vitamin D, which the body uses to help absorb calcium, may help women to reduce their risk of hip fracture, even when osteoporosis is present," observed Dr. Evan C. Hadley, NIA Associate Director for geriatrics research.
"Osteoporosis leads to more than 300,000 hip fractures each year, causing pain, frequent disability, and costly hospitalizations or long-term care. "Prevention of such fractures would greatly improve the quality of life for many older women and men, as well as significantly reduce medical costs." The bones in the body often undergo rebuilding. Some cells, osteoclasts, dissolve older parts of the bones. Then, bone-building cells known as osteoblasts create new bone using calcium and phosphorus.
As people age, if osteoporosis develops, more bone is dissolved than is rebuilt, and the bones weaken and become prone to fracture. Also in many older persons, levels of vitamin D in the blood are low because they eat less or spend less time in the sun, which stimulates the body's own production of vitamin D.
Experts do not understand fully the causes of osteoporosis. However, they do know that lack of estrogen which accompanies menopause, diets low in calcium, and lack of exercise contribute to the problem. Eighty percent of older Americans who face the possibility of pain and debilitation from an osteoporosis-related fracture are women. One out of every two women and one in eight men over the age of 50 will have such a fracture sometime in the future. These fractures usually occur in the hip, wrist, and spine.
Sleep Apnea, Diabetes Link Found. Adults who suffer from obstructive sleep apnea are three times more likely to also have diabetes and more likely to suffer a stroke in the future, according to a new UCLA School of Dentistry/Department of Veterans Affairs study published today in the Journal of Oral and Maxillofacial Surgery. Sleep apnea, a serious condition marked by loud snoring, irregular breathing and interrupted oxygen intake, affects an estimated nine million Americans. The culprit? Carrying too many extra pounds.
"The blame falls squarely on excess weight gain," said Dr. Arthur H. Friedlander, associate professor of oral and maxillofacial surgery at the UCLA School of Dentistry and associate chief of staff at the Veterans Affairs Medical Center in Los Angeles. Surplus weight interferes with insulin's ability to propel sugars from digested food across the cell membrane, robbing the cells of needed carbohydrates. Diabetes results when glucose builds up in the bloodstream and can't be utilized by the body. Being overweight can also lead to obstructive sleep apnea, according to Friedlander.
"When people gain too much weight, fatty deposits build up along the throat and line the breathing passages," he explained. "The muscles in this region slacken during sleep, forcing the airway to narrow and often close altogether." Reclining on one's back magnifies the situation. "When an overweight person lies down and goes to sleep," Friedlander said, "gravity shoves the fat in the neck backwards. This blocks the airway and can bring breathing to a halt."
Friedlander tested the blood sugar of 54 randomly selected male veterans whom doctors had previously diagnosed with obstructive sleep apnea. He discovered that 17 of the 54 patients, or 31 percent, unknowingly suffered from adult-onset diabetes. Using the same sample, Friedlander also took panoramic X-rays of the men's necks and jaws. The X-rays indicated that 12 of the 54 patients, or 22 percent, revealed calcified plaques in the carotid artery leading to the brain.
These plaques block blood flow, significantly increasing patients' risk for stroke. Seven of the 12, or 58 percent, were also diagnosed with diabetes. In dramatic comparison, the 17 patients diagnosed with diabetes showed nearly twice the incidence of blockage. Seven of the 17 men, or 41 percent, had carotid plaques. Only five of the 54 patients who displayed plaques did not have also diabetes. If he conducted this study today, Friedlander notes, he would likely find a higher number of diabetic patients. After he completed the study in 1997, the American Diabetes Association lowered its definition for diabetes from 140 to 126 milligrams of sugar per deciliter of blood.
"This is the first time that science has uncovered a link between sleep apnea and diabetes," said Friedlander. "The data suggest that someone afflicted with both diabetes and sleep apnea is more likely to suffer a stroke in the future." "Persons going to the doctor for a sleep-apnea exam should request that their blood be screened for diabetes, especially if they are overweight," he cautioned. More than half of the individuals who develop diabetes as adults will need to modify their diet and take daily insulin in order to control the disease, he added.
Stress, Surgery May Increase CA Tumors. Stress and surgery may increase the growth of cancerous tumors by suppressing natural killer cell activity, says a Johns Hopkins researcher.
Malignancies and viral infections are in part controlled by the immune system's natural killer (NK) cells, a sub-population of white blood cells that seek out and kill certain tumor and virally infected cells. In a study using animal models, natural killer cell activity was suppressed by physical stress or surgery, resulting in a significant increase in tumor development.
These findings suggest that protective measures should be considered to prevent metastasis for patients undergoing surgery to remove a cancerous tumor, according to Gayle Page, D.N.Sc., R.N., associate professor and Independence Foundation chair at the Johns Hopkins School of Nursing. "Human studies have already found a connection between the level of NK activity and susceptibility to several different types of cancer," says Page, an author of the study.
"We sought to determine the importance of stress-induced suppression of NK activity and thus learn the effects of stress and surgery on tumor development. "Many patients undergo surgery to remove cancerous tumors that have the potential to spread. If our findings in rats can be generalized to such clinical settings, then these circumstances could increase tumor growth during or shortly after surgery." The research was conducted at Ohio State University College of Nursing and the Department of Psychology at UCLA, where Page held previous positions, and at Tel Aviv University.
Results of the study are published in the March issue of the International Journal of Cancer. In laboratory studies, Page and her colleagues subjected rats to either abdominal surgery or physical stress, and then inoculated them with cancer cells. In the rats that had undergone surgery, the researchers observed a 200 to 500 percent increase in the incidence of lung tumor cells, an early indicator of metastasis, compared with rats that had not received surgery.
The experiment also showed that stress increased lung tumor incidence and significantly increased the mortality in the animals inoculated with cancer cells. "Our results show that, under specific circumstances, resistance to tumor development is compromised by physical stress and surgical intervention," says Page.
"Because surgical procedures are life-saving and cannot be withheld, protective measures should be considered that will prevent suppression of the natural killer cell activity and additional tumor development. "Researchers do not yet know how to prevent surgery-induced immune suppression, but early animal studies have shown increased use of analgesia reduces the risk."
The study was funded by the National Institutes of Health, and the Chief Scientist of the Israeli Ministry of Health. Lead author was Shamgar Ben-Eliyahu, Ph.D., and other authors were Raz Yirmiya, Ph.D., and Guy Shakhar.
The Joints Are Jumping
June 11, 2005 04:56 PM
The Joints Are Jumping by Rachel Alexander Energy Times, October 8, 2003
It usually starts with a twinge in your back or an ache in your knees: Knee stiffness, back pain and joint inflammation can signal the beginning of arthritis.
According to the US Food and Drug Administration, arthritis affects over 42 million Americans-that's 1 in every 3 adults-and costs the economy nearly $65 billion annually. But as common as arthritis is, it doesn't have to extract a high cost from your joints.
Who's At Risk?
Arthritis literally means an "inflammation of the joints" and can affect anyone-from small children to 80-year-olds. Some groups are more prone to certain types of arthritis; for instance, those over 40 are at greater risk for developing osteoarthritis, a degenerative condition of the joints.
According to Johns Hopkins Medical Institute, more than 50% of all individuals over the age of 40 have x-ray signs of osteoarthritis in weight-bearing joints (such as those in the knees and hips), and nearly half of those over 65 have measurable symptoms of arthritis. Osteoarthritis is often caused by overuse, age, excess weight or genetics, or by a combination of these factors.
Rheumatoid arthritis, on the other hand, is a disease of the immune system that affects the joints, which can make it harder to diagnose because early symptoms-fatigue, weakness, loss of appetite and low-grade fever-can mimic other chronic conditions.
Stiffness and pain may or may not accompany the initial symptoms of rheumatoid arthritis. However, joints eventually become inflamed and swollen. Although less common that osteoarthritis, rheumatoid arthritis affects more than 2 million Americans.
Covering Up the Signs
Treating arthritis can involve the use of both conventional and non-conventional therapies.
"In osteoarthritis specifically, conventional medicine has just been focused on covering up the symptoms," says Jason Theodosakis, MD, author of The Arthritis Cure (St. Martin's Press). "In the history of medicine, this approach has been considered primitive."
But Dr. Theodosakis points out that treatment often depends on the type of arthritis involved: "Rheumatoid arthritis patients should be taking prescription drugs that are known to prevent the disease from progressing. [Use] alternative medicine as an adjunct..."
Conventional therapies often involve the use of non-steroidal anti-inflammatory (NSAID) medicines, such as ibuprofen and naproxen. The chief drawback of NSAIDs is the toll these treatments extort from the gastrointestinal system.
In fact, a 2002 study conducted by researchers at the University of South Florida, Tampa, found that more than 15% of patients developed digestive problems after a five-week course of ibuprofen. In addition, ibuprofen may increase blood pressure.
Newer prescription NSAIDs called COX-2 inhibitors, which work by suppressing the body's inflammatory response, also carry risks of side effects ranging from diarrhea and fluid retention to liver damage and kidney problems. In addition, people with asthma or chronic allergies (including to aspirin) should not take these medicines.
Corticosteroids-another treatment option that has been used to lessen inflammation-can cause side effects such as increased appetite, mood changes and even immune system breakdown.
A growing body of evidence shows that nutrients such as glucosamine and MSM, coupled with lifestyle changes, can help decrease or eliminate some of the aches and pains of arthritis. Glucosamine is a natural chemical that helps build joints. When the cartilage in joints deteriorates due to age or other factors, studies indicate that glucosamine provides the necessary building blocks for rebuilding and repairing this tissue.
In one investigation (Archives of Internal Medicine 2002; 162:2113-23), scientists discovered that glucosamine slowed the progression of osteoarthritis and improved symptoms for over 200 patients. Another study, conducted by researchers in the Netherlands, demonstrated that a combination of glucosamine and chondroitin holds promise for conditions such as spinal disc degeneration.
To date, several studies have confirmed glucosamine's ability to help the symptoms of arthritis, and the National Institutes of Health is currently supporting research to further study the benefits of glucosamine.
Other Joint Aids
MSM is often an adjunct therapy as it does not work directly on joints, but provides the raw materials, in this case sulfur, to help rebuild cartilage in the joint matrix. Studies indicate that sulfur has a protective effect and may interact with magnesium, an essential bone nutrient.
Traditionally, the herb horsetail (Equisetum arvense) has been used to supply silica, a mineral component of nails, bones and joints. Its support of these structures can help in the fight against arthritis.
As the body ages, it may lose much of its silica reserves. Resupplying much of this mineral may help support joints. In addition, experts believe, silica can help the body use calcium more effectively and support bone health.
Since rheumatoid arthritis is a systemic affliction, you should work with a trained health professional in treating it. Complementary care practitioners often use antioxidant nutrients, such as vitamins C and E, to reduce free radical damage, along with pantothenic acid (vitamin B5) to lessen morning stiffness.
A Joint Project
According to Dr. Theodosakis, exercise is the key to dealing with arthritis: "[Start with] an individualized exercise program that strengthens the joints without causing more damage...and an eating program to control your weight if you are currently overweight." To limit the effects of arthritis, you should quit smoking, since smoking generates free radicals that can harm the tissues which make up joints. In addition, a strict vegan diet may help alleviate some of the pains of rheumatoid arthritis.
Dr. Theodosakis also recommends looking for hidden causes of symptoms, such as food allergies, that may contribute to arthritis.
Heat helps ease arthritis pain and encourages both blood flow and tissue repair. A plain, old-fashioned hot water bottle works quite well. Or you can use one of the newer heat-generating wraps, which are thin enough to be worn under clothing and don't have to be constantly reheated.
You can't always avoid arthritis, especially as you get older. But you don't have to let it get the better of you.
Basics of the Immune System
June 10, 2005 03:01 PM
Basics of the Immune System
by Leonid G. Ber, MD Energy Times, September 1, 1998
In a world filled with pathogens and microbes, good health and resistance to disease is no accident. It requires a vigorous and vigilant immune system. The immune system should be viewed as an internal security force that is constantly checking the identity of everything entering and already existing in the body. A cell or substance may be recognized as "non-self" and a potential enemy if it does not have the right molecular make-up. A cell displaying molecules produced according to a different blueprint than the body's own code may be recognized as foreign. To eliminate alien material that may harm the body, the immune system must take swift action.
Recognizing entities that originate outside the self forms the key to overall immune system response. This key is carried in the body by cells called macrophages (ma-kro-fajs), a name derived from a Greek term meaning "big eater." Macrophages eat or engulf foreign cells and molecules. When a macrophage encounters something that it distinguishes as being "non-self" or abnormal, it can attack the enemy with a series of assault weapons, including free-radicals (reactive substances) and enzymes, that dissolve and weaken the intruder. In fact, an enzyme produced by macrophages called lysozyme is recognized as one of nature's most powerful anti-infective agents. These chemical defenses, along with engulfment and complete digestion by macrophages, can effectively stymie invasion by disease-causing pathogens.
Harmful invasion can originate in the body's own cells as well as begin from outside sources. While we are constantly exposed to bacteria, viruses, fungal cells and parasites, destructive cancerous growths often start within the body.
Every day, thousands of the body's cells mutate into possible cancers. Under most circumstances, the immune system keeps these cells under control. But when the immune "security" system slips up, these harmful growths multiply unrecognized.
The initial immune response that recognizes invaders is called a "non-specific defense mechanism" since this immune response is generally the same toward all invaders. This counter-attack entails battling every invader pretty much identically: a macrophage can engage, dissolve, weaken, engulf, digest, eliminate. However, if, despite the initial immune efforts, the problem persists, a macrophage can tag an invader and "introduce" it to the rest of the immune system, thus recruiting more specialized types of immune cells to enter the battle. This tagging function endows macrophages with the name "antigen-presenting cells." (Antigens are substances that can provoke specific responses by the immune system.)
Most antigens are proteins. Proteins are relatively large molecules made of smaller units called amino acids. The specific geometric organization of amino acids is what conveys uniqueness to each protein. (Your genetic code forms a blueprint for the production of your own, individual proteins.) Protein molecules produced by one human being can act as an antigen for another human being. That's why organs transplanted from one person to another can be rejected by the immune system. Unless organs are transplanted from one identical twin to another (who share the genetic blueprint for protein creation), doctors must use immune-suppressing drugs to curtail organ rejection. At the same time as these medicines prevent transplant rejection, they also make people more susceptible to infectious diseases and cancer.
After one set of immune cells chemically tags antigens (invaders) for recognition, other highly specialized parts of the immune system go into action: Cells called T cells or T lymphocytes acknowledge the invaders and can take the further action (second line of defense) that is necessary to render them harmless.
T cells get their name from the thymus (an organ located behind the sternum) where they originate. The thymus, most active when we're young, usually shrinks and apparently slows or shuts down its activity about the age of forty.
A wide variety of T cells inhabit lymph nodes (soft, usually round, pea- or nut-sized organs) and other body areas. For instance, natural killer cells, as their name implies, are a particularly aggressive type of T cell. Another type of T cell is called T helper (a cell that supports development of immune response). T suppressors halt immune response when infection ends.
In order to make all these different cells work in concert, cytokines or messenger molecules are produced that facilitate constant communications between all the parts of the immune system.
The B Team
Other organs of the immune system include:
*bone marrow: a powerful cell producing organ where the majority of immune cells are born;
*spleen: an abdominal organ that forms a reservoir for the production of immune cells.
Lymph nodes oversee particular segments of the body where they collect and recycle tissue fluids. Like an early warning system, lymph nodes react when an invader is detected in the part of the body that it controls.
Yet another step in the so-called immune cascade entails action by lymphocytes, called B cells, which originate in the bone marrow. These cells produce antibodies which are immune proteins (immunglobulins) that attack specific antigens.
While traveling in the blood, an antibody can bind to an antigen, curtailing its harmful action. This bound up molecule forms a complex easily recognized by scavenging macrophages which make a quick meal out of the unlucky invader.
After enemy cells are removed from the body, knowledge of this victory resides in the immunological memory prolonging your resistance toward specific disease pathogens indefinitely. That's why someone who has recovered from a disease like the measles may be impervious to reinfection.
Rules for Optimum Immunity
Even though the immune system consists of a complex team of hard-working cells, enhancing your immunity is relatively easy:
Maintain a healthy lifestyle. Avoid continuous stress and negative emotions or cope with them through exercise or meditation. Consistent, moderate exercise can boost the immune system. Massage can also help although extreme care must be taken when inflammation or disease is already present.
Sleep 7-8 hours a day. Sleep allows the body to recover and rebuild. Protein synthesis, vital for a healthy immune system, increases during the night.
Stick to a healthy diet. Your immune system consists of trillions of cells. Consequently, nutrients important for cell health boost the immune system. A balanced low-calorie diet rich in complex carbohydrates, "good" fats (including fish oils, olive oil and flaxseed oil) along with vitamins, minerals and phytonutrient antioxidants from fresh fruits and vegetables can fortify immune cells. Plus, drinking plenty of water helps improve circulation of lymph fluid.
These recommendations are not hard to meet once they become a part of your daily routine. However, extra immune security may be necessary during flu season, while traveling long distances (airplanes are notorious sources of pathogens) or when working extensive hours in front of a computer screen. In addition, exposure to x-rays, immunosuppressive chemicals, ultraviolet radiation (the sun) or simply aging may give your immune cells extra burdens.
Your "specific" immune system does not respond immediately to the challenge of invasion by an infectious organism. Instead, it may require about 2 weeks for an effective reaction after antigen recognition and alerting T cells. During this period, the macrophages' non-specific defense assumes a crucial role in keeping infection in check.
Enhanced activity by macrophages is especially important for recognizing and destroying cancer cells. The most dangerous cancers are those that can mimic normal cells and avoid the immune system's wrath. Few substances can activate macrophage function in the body (aloe vera contains substances that contribute to this process). The most powerful macrophage activator recognized by the scientific community is a sugar-like substance called beta-1,3-D-glucan. Beta-glucan, extracted from the cell walls of common Baker's yeast, when taken in certain small amounts, can prevent infection by making macrophages more active in recognizing and attacking infectious bacteria, fungi and certain viruses.
This kind of activation can encourage macrophages to attack previously unrecognized tumor cells. As a result, tumors may be eradicated as the immune system mobilizes and produces what may be known as "spontaneous healing."
When a macrophage works overtime fighting disease, its demand for nutrients and energy increases dramatically. Vitamin C, known for its immune supporting function, seems to be especially important for maintaining fully active macrophages. Vitamin C collects in macrophages, often reaching forty times the concentration found in surrounding blood. What are conventionally considered normal amounts of vitamin C in the body may be insufficient to keep macrophages well supplied with this antioxidant. Therefore, extra amounts of vitamin C can keep the immune system in fighting trim.
Scientists are only now beginning to uncover the secrets of the highly organized immune system. One thing's certain: The immunity security team depends on proper lifestyle, nutrition and supplements to maintain the critical defenses necessary for good health.
Dr. Ber received his doctorate in internal medicine from the Yaroslavle, State Medical Institute in Yaroslavle, Russia.
Resveratrol - New Hope for Long Life ...
June 06, 2005 08:23 AM
We all want to live long, vibrant and healthy lives. At one time intervention in the aging process was regarded as mere fantasy—but today it is within our reach due to breakthroughs in nutritional science. Resveratrol, a compound that is abundant in red wine, has been making headlines recently for its anti-aging potential and its well-documented antioxidant and cardiovascular benefits. Resveratrol has been shown in new research at Harvard Medical School to increase the lifespan of yeast cells—a finding that may help explain the lifeextending effects of the Mediterranean diet. Now Source Naturals offers you RESVERATROL from a non-alcoholic source. RESVERATROL is part of Source Naturals’ extensive line of scientifically based nutrients, designed to help you shape a successful anti-aging program.
Resveratrol in the News
Researchers at Harvard Medical School recently made headlines when they identified a plant molecule they believe may hold the key to slowing the human aging process. The compound, resveratrol, is produced by grapevines and other plants in response to environmental stress. The groundbreaking study, reported in the journal Nature, showed that resveratrol mimics the life-extending effects of calorie restriction and increases the lifespan of yeast cells by up to 80%. Resveratrol was found to activate certain enzymes that influence the genes that regulate aging. This research may help explain the long-established association between moderate red wine consumption and cardiovascular health and longevity.
Wide-Ranging Anti-Aging Benefits
Previous research has documented resveratrol’s many health benefits:
A Non-Alcoholic Source
Most publicity about resveratrol focuses on its presence in grape skins and red wine. However, this beneficial compound is found in other plants. Source Naturals RESVERATROL is a standardized extract of Hu Zhang root, a celebrated traditional Chinese herb. This offers consumers the advantage of a non-alcoholic source. Each tablet contains 500 mg of Hu Zhang extract, yielding 40 mg of resveratrol activity. RESVERATROL is available in bottles of 30 or 60 tablets.
Source Naturals, the science company, is pleased to partner with your natural foods retailer in bringing you this botanical treasure. For a long and vital life, RESVERATROL belongs at the center of your anti-aging regimen.
May 09, 2005 06:10 PM
It's in the BloodNatural alternatives abound for managing cholesterol levels, backed by a growing body of research ©VR By Paul Bubny
The National Cholesterol Education Program (NCEP) last July lowered the threshold for considering the use of statin drugs—a move which some say was motivated more by profits than scientific evidence. For example, the Center for Science in the Public Interest pointed out that eight of the nine authors behind the new recommendations had financial ties to statin manufacturers, which stand to reap billions of dollars more from a category that grossed $14 billion in the U.S. last year. And though the Food and Drug Administration (FDA) in January decided against authorizing over-the-counter (OTC) sales of statin drugs, drug companies would still like to see this happen.
“The medical establishment’s pushing of these drugs to becoming the number one category of prescribed drugs in the world has led them to keep lowering the total cholesterol number that triggers the drug recommendation,” said Neil E. Levin, C.C.N., D.A.N.L.A., nutrition educator, product formulator, and “Truth Advocate” for NOW Foods (Bloomingdale, IL), which produces a number of supplements for addressing cholesterol. “This is despite the lack of evidence that total cholesterol means much as regards cardiovascular risks.
“Other tests are much more important in terms of predicting risks, including CRP (C-reactive protein), the balance of different cholesterol fractions, and homocysteine,” he continued. “Add adult-onset diabetes to the risk factors for cardiovascular disease (CVD).”
At the same time, the allegation that enormous sales potential lay behind the lower threshold for prescribing statin drugs illustrates how widespread the problem of hypercholesterolemia (elevated total cholesterol) is. More than 100 million Americans have elevated cholesterol (total cholesterol values of 200 mg/dl and higher), and of these, more than a third have high cholesterol (levels of 240 mg/dl and higher), according to the American Heart Association. Those numbers have unfavorable implications for the incidence of CVD, as high cholesterol is considered a risk factor for coronary heart disease and stroke.
While statin drugs haven’t garnered the same degree of negative publicity that COX-2 inhibitors have suffered lately, safety concerns have arisen nonetheless. For one thing, these drugs lower the liver’s production of coenzyme Q10 (coQ10) along with its production of cholesterol. “CoQ10 is related to energy production and immune functions, is an antioxidant, and [is] an important cardiovascular nutrient,” Levin said. “It is not good to lower one’s coQ10 levels by half!”
Moreover, said Levin, statins increase the tendency of muscle tissues to break down. “Combined with inactivity or certain drugs, this can stimulate muscle wasting,” he said. “Muscle is where a good deal of calories are burned, so a loss of muscle could affect mobility and energy production, potentially adding to obesity problems. These muscle changes occurred in patients and persisted for years after treatment was discontinued, as shown by muscle biopsies, even if no obvious muscle problems were observed by the patients.”
And the last word on the subject may not have been spoken. Predicted Dr. Frank King, Jr. president of King Bio Natural Medicine (Asheville, NC), “Once the appropriate studies are finished, these drugs, along with hypertensives, will hit the fan bigger than the COX-2 inhibitors.”
Also looking toward the future, Levin said that of the 20 million Americans who will be “targeted” for statin drug prescriptions under the new NCEP guidelines, “Some of these will want to try natural methods first. Others will rebel at the side effects of the drugs and experiment with alternative products.”
King and Levin both saw opportunity for natural products in the fallout from drug safety concerns, with King projecting that sales of his company’s cholesterol-related homeopathic remedies will double in 2005. “The reports of deaths from drugs will always overshadow the trumped-up studies and news reports blasting dietary supplements,” said Levin. “Vioxx knocked vitamin E off the media’s radar screens pretty rapidly, though we still see ignorant reporters citing that [Johns Hopkins] vitamin E analysis as if it were true. But the comparable safety of supplements means that open-minded people will want to at least try natural therapies before signing in to a lifetime of drug therapies. Meanwhile, the studies on natural products will continue to build our credibility.”
Those studies keep coming in, with at least four major findings published in the past few months, plus a heart-health claim on walnuts authorized by FDA. They join a raft of earlier findings that link natural products—branded and otherwise—to healthy cholesterol levels.
"Blur of Products"
With so many natural alternatives to cholesterol drugs available, it can be hard to keep track. “As with any other category, the blur of products as they cascade over several shelves means that the retailer needs to have a good sense of what works and what they want to recommend to their customers,” Levin said. “Really, each person needs a protocol that would include antioxidants, fiber, vitamins, herbs, and oils. The pre-mixed cholesterol support formulas are a good starting place.”
To help retailers get a sense of “what works,” here is an alphabetical discussion of several nutrients that have demonstrated benefits in serum cholesterol levels. They include the following:
Barley may help lower cholesterol, according to a report in the American Journal of Clinical Nutrition (2004, vol.80, no.5: 1185-1193). Twenty-five adults with mild hypercholesterolemia consumed a controlled diet low in total fat, saturated fat, and cholesterol for 19 weeks. They then added whole-grain products containing barley to their diets that contained low (0 g), medium (3 g), or high (6 g) amount of beta-glucan per day for five weeks. Total cholesterol was reduced by 4 percent 9 percent, and 10 percent, respectively. The diet with the highest amount of beta-glucan led to a decrease in LDL cholesterol of 17 percent.
Chromium. There’s evidence, Levin said, that chromium in doses of 500 mg a day may decrease levels of low-density lipoprotein (LDL, the so-called “bad” cholesterol) and total cholesterol while raising levels of high-density lipoprotein (HDL, or “good” cholesterol). At the annual meeting of the American College of Nutrition last October, a poster presentation on the safety of Benicia, CA-based InterHealth Nutraceuticals’ ChromeMate niacin-bound chromium won first prize; among other things, the presentation cited chromium’s role in maintaining healthy blood lipid levels.
Fatty Acids. The latest in a long line of studies demonstrating the benefits of fatty acids in heart health is a study published in The International Journal of Clinical Pharmacology and Therapeutics in December 2004. It showed that docosahexaenoic acid (DHA), an omega-3 fatty acid, can restore normal blood vessel function in children with inherited high cholesterol. The study, which used Martek DHA produced from microalgae, concluded that restoration of normal blood vessel function has the “potential for preventing the progression of early coronary heart disease in high-risk children.”
“The evidence continues to accumulate on the cardiovascular benefits of DHA for people of all ages,” said Henry “Pete” Linsert, Jr., chairman and CEO of Martek Biosciences, an ingredient supplier based in Columbia, MD. “This study clearly indicates that DHA played an important role in healthy blood vessel function in the children in this study.”
On the Omega-Research.com Website maintained by fish oil manufacturer Nordic Naturals (Watsonville, CA) can be found summaries of several earlier studies linking omega-3 fatty acids to maintaining healthy blood lipid levels, as well as related benefits such as elasticity of the arteries. In a 2003 study published in the American Journal of Clinical Nutrition, it was found that women receiving a mixture of 4 g eicosapentaenoic acid (EPA) and DHA along with 2 g of gamma-linolenic acid (GLA) had lower levels of LDL cholesterol after 28 days compared to those who received either the EPA/DHA supplements without DHA, EPA/DHA with a smaller dose of GLA, or GLA alone.
Flax is another source of omega-3s, and Arkopharma/Health From The Sun (Bedford, MA) offers FiProFLAX in a variety of forms. Marketing director Hugues P. Mas said the flax is “QAI [Quality Assurance International] certified organic and guaranteed GMO [genetically modified organism]-free.” On its Website, the company offers a cholesterol quiz geared to consumers, discussing the importance of omega-3s as well as other nutrients.
Garlic. Adding to an already considerable body of research demonstrating that garlic can lower total cholesterol, LDL cholesterol, and triglycerides while increasing HDL cholesterol, researchers at UCLA in 2003 reported that Kyolic aged garlic extract reduced or inhibited plaque formation in the arteries of 19 cardiac patients taking statin drugs.
Lead researcher Matthew Budoff, Ph.D. commented at the time that the study “suggests that aged garlic extract may be a useful and beneficial dietary addition for the people who have high cardiovascular risk or who have undergone heart surgery.” Budoff has since presented several trade show seminars sponsored by Los Angeles-based Wakunaga of America, the makers of Kyolic.
Guggul. In use for centuries as a component of Ayurvedic medicine, guggul—a gummy resin tapped from the Commiphora mukul tree, which is native to India—has been studied since the early 1960s for its hypolidemic (blood-lipid lowering) properties. Sabinsa Corp. (Piscataway, NJ), an ingredient supplier which produces a standardized extract under the brand name Gugulipid, says the studies on guggul indicate that its hypolipidemic activity can be attributed to more than one mechanism of action.
Among the possible mechanisms are: inhibition of cholesterol biosynthesis, enhancing the rate of excretion of cholesterol, promoting rapid degradation of cholesterol, thyroid stimulation, alteration of biogenic amines, and “high affinity binding and anion exchange.”
Homeopathy. “Homeopathy activates the body’s own control system to work properly,” said King. “This is the safest and most curative approach to take.
“Forcing the body into biochemical change even naturally doesn’t actually have the curative action of homeopathy,” King continued. “Homeopathy can even correct the genetic predispositions to disease we may have inherited from as deep as a thousand years into our family chain.” King Bio makes Artery/Cholesterol/BP, a homeopathic formula intended to help tone heart muscles and blood vessels.
Low glycemic index foods. In a study published in the February issue of the American Journal of Clinical Nutrition, researchers found that high glycemic load is negatively correlated to serum levels of HDL cholesterol. Assessing the relationship between blood levels of lipids and diet in a test population of 32 healthy males and females ages 11 to 25, the researchers found that glycemic load accounted for 21.1 percent of the variation in HDL cholesterol. They concluded that glycemic load appears to be an important independent predictor of HDL cholesterol in youth and noted that dietary restrictions without attention to glycemic load could unfavorably influence blood lipids.
Medicinal Mushrooms. Although its product SX-Fraction is intended primarily to address high blood sugar, Maitake Products, Inc. (MPI, Ridgefield Park, NJ) found in a clinical study that LDL cholesterol in diabetic patients declined modestly (from 142 mg/dl to 133 mg/dl) over a two-month period. Those taking SX-Fraction also lost about 7 lbs. in the same time period.
“The more impressive lowering of cholesterol, however, comes from the dietary fiber that is found in all medicinal mushrooms,” said Ellen Shnidman, manager of scientific affairs at MPI. She cited animal studies which documented the cholesterol-lowering properties of four different mushrooms: maitake, shiitake, agaricus, and enokitake.
For example, a study reported in the September 1996 issue of Alternative Therapies showed “a 44 percent reduction in total cholesterol in rats consuming maitake mushroom in their diet,” said Shnidman. “This cholesterol reduction is accompanied by weight loss, relative to rats eating a similar high-choelsterol diet without mushrooms. Apparently, cholesterol is excreted by the rats in sufficient quantity to aid in weight loss.”
Oat bran. A 2004 consumer study conducted by the Natural Marketing Institute (NMI, Harleysville, PA) for Nurture, Inc. (Devon, PA), which produces the ingredient OatVantage, found that 63 percent of consumers managing their cholesterol levels prefer oat-based ingredients.
Oat bran is the subject of a health claim authorized by FDA in 1999, and NMI research found that 69 percent of respondents preferred the FDA-permitted health claim, “Helps Lower Cholesterol,” over the model structure-function claim, “Helps Maintain Healthy Cholesterol Levels.” “This is significant for food, beverage, and dietary supplement manufacturers who want to increase sales by using a more consumer-desired claim on the product label,” said Griff Parker, Nurture CEO.
Plant sterols. Also the subject of an FDA-approved claim for heart health, plant sterols (structurally similar to cholesterol in humans) can block the absorption of cholesterol, according to a number of studies. In an “Ask the Doctor” publication (available online at www.atdonline.org), Decker Weiss, N.M.D. noted that sterols enter the same receptor sites that cholesterol enters on its way to the bloodstream. “The cholesterol, being blocked from absorption, remains in our intestines where it is eventually excreted,” Weiss wrote. General Mills has just introduced Yoplait Healthy Heart, a yogurt high in plant sterols.
Policosanol. A mixture of fatty alcohols derived from sugar cane or beeswax, policosanol has been favorably compared in clinical studies to several types of prescription drugs for managing cholesterol. On its own, policosanol was found in a 1999 study to reduce LDL cholesterol while raising levels of HDL cholesterol.
Probiotics. “Several studies have indicated that consumption of certain cultured dairy products resulted in reduction of serum cholesterol, as well as triglycerides,” wrote Dr. S.K. Dash, president of probiotic manufacturer UAS Laboratories (Eden Prairie, MN), in his Consumer Guide to Probiotics. Among other studies, Dash cited two controlled clinical studies from the VA Medical Center at the University of Kentucky.
“In the first study, fermented milk containing [Lactobacillus] acidophilus was accompanied by a 2.4 percent reduction of serum cholesterol concentration,” he wrote. “In the second study, a different L. acidophilus strain reduced serum cholesterol concentration by 3.2 percent. Since every 1 percent reduction in serum cholesterol concentration is associated with an estimated 2 to 3 percent reduction in risk for coronary heart disease [CHD], regular intake of fermented milk containing an appropriate strain of L. acidophilus has the potential of reducing risk for [CHD] by 6 to 10 percent.”
Dash said his company’s DDS Probiotics contain DDS-1 L. acidophilus, “which has been researched and demonstrated to show cholesterol-lowering effect.”
Psyllium. “Internal cleansing is very important” in maintaining healthy cholesterol levels, “especially if you do it with a lot of fiber,” said Sunil Kohli, vice president of Chino, CA-based Health Plus, Inc. The cholesterol-managing ability of fiber in general and psyllium in particular is “very well-established,” he said.
However, Kohli said, “It will probably do you no good if it’s random. It should be done on a regular basis, and it should be supervised. Consulting the doctor or pharmacist is important.”
Soy. The protein in soy “has evidence of lowering total cholesterol and LDL cholesterol, based on reviews of studies using over 20 g of soy protein per day,” said Levin. “Soy isoflavones are considered only partly responsible for this effect.”
Sytrinol. A patented proprietary formula derived from natural citrus and palm fruit extracts and containing citrus polymethoxylated flavones and palm tocotrienols, Sytrinol has been shown in clinical trials to improve total cholesterol, LDL cholesterol, and triglycerides by up to 30 percent, 27 percent, and 33 percent, respectively. Having just wrapped up Phase III of a long-term trial of Sytrinol, Chicago-based SourceOne Global Partners, which owns the exclusive worldwide license for intellectual property associated with the ingredient, is commencing a study that combines Sytrinol with plant sterols.
Tocotrienols. On its Website discussing the science and benefits of tocotrienols (www.tocotrienol.org), ingredient supplier Carotech Inc. (Edison, NJ) identifies several benefits for blood lipid levels. Tocotrienols, according to the Website, have been shown to “inhibit cholesterol production in the liver, thereby lowering total blood cholesterol;” “[suppress] hepatic HMG-CoA reductase activity [and result in] the lowering of LDL cholesterol levels;” and “inhibit cholesterogenesis by suppressing HMG-CoA reductase.”
With all of this, Levin said, it’s important for retailers to remember that “they are not allowed to discuss diseases and remedies unless there is an approved FDA health claim allowed on the label, as with soy protein and plant sterols. What is allowed are structure-function claims such as ‘cholesterol support,’ ‘promoting normal, healthy circulation,’ ‘homocysteine regulators,’ etc.”
Supplementation is only one tool for managing cholesterol levels, manufacturers pointed out. “Besides nutrition, lifestyle is a key to controlling cholesterol,” Levin said. “Eating a variety of antioxidant-rich foods will prevent the liver from churning out cholesterol as a ‘cheap’ antioxidant. The body uses oxidized cholesterol to patch leaky and damaged blood vessels, so the ability to build healthy collagen is a must, using nutrients like vitamin C, Pycnogenol, rutin, hyaluronic acid, and MSM.
“Don’t forget exercise and stress reduction,” he added. “Stress results in high cortisol levels—usually accompanied by poor blood lipid levels—and a lack of good sleep to produce unhealthy people.” VR
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