Search Term: " Auism "
Can sulforaphane help children with autism?
May 10, 2019 10:46 AM
Cruciferous vegetables such as broccoli have enormous amounts of sulforaphane. Research has even shown that when this compound is taken in large quantities, it can help alleviate the problem of autism in children. Autism is a very important consideration because it affects about one in ten children right now; this is according to experts. New cases are also increasing worldwide. The author states that the recent increases in autism reporting is due to the fact that vaccination schedules in children are increasing and vaccines deliver toxins to the child which can damage the nervous system. Sulforaphane though has been shown to be a chemical that can help in alleviating autism in children even after they have been vaccinated. The research was carried out by scientists at the John Hopkins University who found out that eating foods that have enormous amounts of sulforaphane can help autistic children by enhancing their social skills, verbal communication ability, and their general behavior. The compound, sulforaphane, acts through activating the genes that shield the cells from inflammation, damage to the genetic material, oxidative stress, and other factors that are linked to autism. The study was published in the journal Proceedings of the National Academy of Science.
"The results of their experiment showed that the sulforaphane group demonstrated considerable improvements in social behavior by the time of the fourth week of treatment."
Read more: https://www.naturalnews.com/2019-04-20-can-sulforaphane-help-children-with-autism.html
Reduces homocysteine levels and acts as an Alzheimers bodyguard?
March 12, 2019 01:50 PM
The prevalence of Alzheimer's is steadily growing, and researchers are growing more and more concerned at the apparent epidemic. Approximately one in six adults will end up experiencing some form of dementia, and this statistic alone is enough to motivate medical experts to find solutions. Some physicians are finding that taking in adequate amounts of omega-3 fatty acids each day can help prevent the stiffening and inflammation of cells that have the potential to lead to a drop in cognitive function related to dementia.
"The influence of marine-based omega-3 fats on physical and mental health has been the subject of intense research for decades, and there’s compelling evidence they can help ameliorate a variety of psychiatric illnesses and degenerative brain disorders, including Alzheimer’s."
Read more: https://www.healthnutnews.com/reduces-homocysteine-levels-and-acts-as-an-alzheimers-bodyguard/
BREAKTHROUGH: Vitamin D supplements taken during pregnancy found toprevent autism in children
March 04, 2019 02:26 PM
Autism is a condition that affects thousands of children across the world. It is believed that autism begins during pregnancy. New research suggests that using Vitamin D supplements during pregnancy is a good way to prevent this devastating condition from occurring. It is exciting news for parents who are trying to conceive who want to ensure their baby has a great start from the very beginning. Learn how much Vitamin D to take and the best supplements to begin!
"Taking vitamin D supplements during pregnancy can prevent the onset of autism spectrum disorder in children, a recent animal study showed."
Read more: https://www.naturalnews.com/2019-01-19-vitamin-d-supplements-taken-during-pregnancy-prevent-autism-in-children.html
9 Health Benefits of Glutathione
January 02, 2019 05:17 PM
Glutathione is made of 3 combined amino acids and is found in alol cells of the body. Its function as an antioxidant is to protect the body cells and tissues from harm posed by free radicals.But it also serves to function as a protective agent in critical body systems, such as the liver, protecting against fatty liver disease, colitis, the endocrine system as it relates to insulin function. One can uptake their intake of this critical protein through supplements or simply by eating foods rich in this complex: broccoli, spinach, garlic, onions, chicken, fish and brown rice to name a few.
"The nutrient, glutathione, is touted by many people as one of the greatest nutritional supplements for preventing countless health conditions, from autism to weight loss and even cancer."
Read more: https://www.care2.com/greenliving/9-health-benefits-of-glutathione.html
Bifidobacterium Lactis: The Bacterium That Could Help You LoseWeight & Fight Inflammation
October 10, 2018 03:26 PM
The probiotic Bifidobacterium lactis, or B. lactis, is a powerhouse for gut health. Why is this strain of bacteria so important? One study published in 2015 showed that B. lactis could improve unpleasant and painful symptoms associated with poor gut motility, dysbiosis, and GI hypersensitivity. B. lactis is definitely one of the “good guys” of the gut bacteria world because it contributes to a healthy and balanced microbiome, which positively affects balanced blood sugar and optimal weight maintenance.
"A particular strain of B. lactis, known as HN019, has been shown to have a significant impact on those with metabolic syndrome. This probiotic had beneficial effects on inflammation, nitric oxide metabolites, and antioxidant measurements, and the authors of the study stated that if their results are confirmed, supplementation with this probiotic should be considered further."
Read more: https://www.mindbodygreen.com/articles/bifidobacterium-lactis-weight-loss-inflammation
CBD Oil Proving Beneficial For Individuals With Autism
June 22, 2018 08:10 AM
CBD, that is cannabis, (marijuana-based) or cannabidiol, (hemp-based) oil is already noted for its positive medicinal affects as an anti-inflammatory agent and a mood-booster and as a compound that mitigates the potential of seizures. It is also gaining ground as a supplement that positively affects those with autism.
Unfortunately, however, while both types of CBD appear to be beneficial to autism-sufferers, it seems that in the case of autism the psychoactive element available in the cannabis, or marijuana-based oil, has an edge over the hemp-based product.
Nonetheless, autism-sufferers and parents of autism-sufferers should know that considerable relief may be possibly obtained even with the hemp-based product, which is already legal, or legal with conditions (although not FDA approved) in many of the fifty states and which will hopefully soon be legal in all of them.
"Marijuana (cannabis) and hemp-derived products, including CBD, are known to provide relief from chronic pain, anxiety, inflammation, seizures, fibromyalgia, autism and other related conditions."
Read more: https://www.autismkey.com/cbd-oil-proving-beneficial-for-individuals-with-autism/
Treating Autism With Cannabis Now Has Scientific Support
October 20, 2017 10:14 AM
Autism is a hard thing to diagnose and treat. There are different forms of it. There are also different levels of severity. Cannabis is one way some treat it even though it is controversial. Most cannabis uses are. There is scientific evidence that this may work. It is at least looking into if you can get past the stigma, though it might not work for everyone. Some don't react to it just like any other medication.
"Looking at the quality of the social interactions, we found that our autistic-like mice tended to dart away from a social interaction and huddle in the corner of their testing box."
Read more: https://www.civilized.life/articles/cannabidiol-treatment-for-autism-scientific-support/
Boy Who Suffered 100 Seizures A Day Has Zero in 300 Days After Being Prescribed Cannabis Oil
September 11, 2017 09:14 AM
Billy, an 11 year old living in Northern Ireland, will be the first person to receive a medical marijuana prescription in the United Kingdom. Billy suffers from severe epilepsy, which prevented more traditional medical treatments. His doctor agreed to prescribe it in the wake of overwhelming evidence of the success of Cannabidiol in treating his condition. Where previously Billy would experience up to 100 seizures a days - Billy has not experienced a seizure since starting his treatment 300 days ago in the United States. His mother also notes that it has helped with Billy's Autism - making better eye contact when he plays and communicates. To celebrate this largely important decision, the family is hosting an event, that already has 600 RSVP's, in support of Billy.
"Before taking the CBD oil, Billy suffered from up to 100 seizures a day, which was severely damaging to his health, because one seizure could kill him."
Read more: https://www.civilized.life/articles/boy-who-suffered-100-seizures-a-day-completely-cured-with-cannabis-oil/
Tackling autism by targeting gut bacteria
June 28, 2017 07:14 AM
The symptoms of autism may be targeted by altering bacteria in the stomach. People with autism tend to have a reoccurrence of gastrointestinal issues. This research, conducted by Dr. Qinrui Li, suggests that the root of GI issues may be a result of an imbalance of good and bad bacteria in the gut. It is suggested that if the gut can be reverted back to a healthier state, that some autism symptoms may be alleviated.
Read more: Tackling autism by targeting gut bacteria
The ABCs of CBD
June 14, 2017 09:14 AM
There is a lot of fear and doubt concerning medical marijuana. A lot of people think it is just bad and that is it. Many of them do not stop to consider the myriad of benefits it can provide to people. It is actually a very useful tool that nature has given to us. One of the benefits is that it can prevent you from taking opioids, which are addictive. There are many different useful compounds found in cannabis.
"CBD has been found to be helpful in treating autism, anxiety, depression, psychosis, insomnia, inflammation, pain and cancer, just to name a few."
Read more: http://vegasseven.com/2017/06/06/the-abcs-of-cbd/
CBD oil helps autistic boy speak again
April 30, 2017 02:14 PM
A Puerto Rican family has successfully treated their son's severe autism with the help of CBD oil derived from hemp. Kalel Santiago, the boy in question, survived cancer in his infancy, but as he grew his parents noticed symptoms of autism. An official diagnosis wasn't far behind. However, with the help of CBD oil, Kalel's symptoms have improved, and he's even begun to speak full sentences at school when he was previously silent. Despite the abundance of anecdotal evidence surrounding the benefits of CBD oil, scientists aren't evaluating its potential.
Read more: CBD oil helps autistic boy speak again
What Is GMO and Why Should We Avoid It?
June 21, 2014 02:40 AM
Cause of GMO
GMO's have been classified by the American Academy of Environmental Medicine as unhealthy, they were able to prove that GMO when ingested can cause organ damage, gastrointestinal as well as immune system disorders. This is due to the fact that GMO contains materials that are left behind the body, it can cause long term problems like accelerated aging as well as infertility. The genes inserted into a genetically modified crop like corn, can get transferred into the DNA of bacteria that is living inside the human body, this interaction can lead to a number of long term health problems.
Negative effects of genetically modified products have been observed in 1996, this was due to the number of Americans expressing a number of illnesses after consuming foods that have been engineered for 9 years.
Allergies increased including digestive problems and autism, while other research has yet to support this claim, many non-profit organizations such as Greenpeace are already making campaigns against the production of GMO infused crops and meat.
What are the other negative impacts of GMO?
1. Cancer causing components - GMO according to the American Public Health Association and American Nurses Association, have stated that the growth hormone present from cow’s milk treated by hormone IGF-1 can lead to cancer.
2. Long term negative effects on the body - GMO components can contaminate forever, it can cross pollinate, and the seeds can travel. Once it infects a certain area, it can contaminate the entire gene pool. This means, that the health of future generations is already compromised and for this reason, the production has to be stopped right away before it infects more population.
3. Dangerous side effects - the mere process of creation of GMO's can produce toxins, carcinogens, allergens and nutritional deficiencies.
The direct production and consumption is already endangering a number of species including bees.
Many governments continue to remain lax about the issue, GMOs are illegally being sold and created in many countries, and people need to learn as much as they can in order to learn how they can prevent GMO products from entering their market.
Why Eat Gluten Free
April 17, 2014 04:48 AM
What is gluten
Gluten intolerance arises when your body cannot digest gluten, which is a protein found in rye, barley and wheat. It makes the immune system to attack small intestines lining’s which causes diarrhea, abdominal pain and nausea. It’s commonly called celiac disease. Apart from celiac or gluten intolerance other health issues caused by gluten have come up.
Check out these insights why you and your family should take gluten free diet:
Recent research has revealed that gluten is related with obesity and weight gain. Gluten is a super carbohydrate and is quickly converted to blood sugar than any carb food. This results in glucose being released into the bloodstream. Insulin supports your body in converting glucose to fat causing a lot of fat deposits.
Ward off diseases
Increased gluten consumption has caused a great rise in several diseases such as ADHD, heart diseases, diabetes and autism. Gluten and disease relationships are still under research but meanwhile it is safer to reduce gluten intake within your family members.
Improves mental health
Different researches have associated Celiac disease with issues such as dementia and nervous system problems. Over the last 60 years, there have been some studies relating patients with Schizophrenia and gluten consumption.
You can find gluten everywhere in pizza, bread, salad dressings, spices, ketchup and cosmetics. An average American person can consume about 130 pounds of wheat every year which makes 70 percent of our carb intake.
If you are suffering from diseases such as Osteoporosis or Parkinson's disease, Rheumatoid Arthritis then taking non gluten diet is the best way of getting healthier quicker. Certain research has shown that eating gluten free diet helps you to take less recovery time when you use along with their treatments.
You can give a try by eliminating gluten and check any change in your healthy condition. Several gluten free food choices are available.
Top reasons why gluten free diet is necessary
January 27, 2014 09:31 AM
What is Gluten
Gluten is a protein found mainly in grains, which include wheat, farro, durum, bulgur, spelt, semolina and many others. It is also found in other foods and is present in some toothpaste brands. Gluten is difficult to completely digest and can cause serious health problems for some people. It is for this reason that many people are increasingly consuming gluten free diet in an attempt at avoiding its negative health effects. The following is a look at the adverse effects of gluten in the human body.
What Gluten can Do
Some people’s bodies react to the presence of the protein by attacking it and the body tissue surrounding it, which results to numerous health problems in the body. Gluten is responsible for a condition referred to as celiac disease, which is a serious form of gluten sensitivity. This disease is considered an autoimmune disease because the body’s immune system attacks the protein and the cells of the digestive tract’s enzymes. This leads to bloating, gas, stomach pain, anemia, skin rashes, muscle cramps and bone pain. Other symptoms include missed periods in women, stunted growth in children, seizures, mouth sores, calcium deficiency, nerve damage and nutrient malabsorption.
Other serious effects of ingesting gluten
Include increased risk of developing some forms of cancer and chronic diarrhea. The protein has also been found to cause intestinal inflammation and degeneration of intestinal lining. Weakened intestines are dangerous because they can permit foreign substances into the blood stream, which is common in persons suffering from celiac disease.
Gluten is also associated with numerous disorders of the brain. Conclusive studies have associated the protein to a condition referred to as cerebellar ataxia. Its symptoms include difficulties in coordinating balance, problems with speech and movement. Gluten free diet results to significant improvement in health for persons suffering from autism, epilepsy and schizophrenia.
It has been observed that gluten may be addictive, which is why many people crave for meals made of wheat and other grains. This has not been conclusively proven but there are studies that suggest that traces of the protein’s exorphins can find their way into the human brain.
Gluten free diet is healthy because it improves a person’s bone density, reducing the risk of osteoporosis. Any people experience significant benefits in their mental, emotional and physical health after eliminating the protein from their diets. It is, therefore, important that a gluten free diet be consumed especially by people who react negatively to it.
What Is Monolaurin And What Are Its Health Benefits?
December 29, 2012 10:38 AM
Get An Immune Boost:
Man has made a big leap as far as science and pharmacology are concerned, but there are still a lot of substances useful to human health that are waiting to be discovered. There are also those substances naturally occurring but whose pharmacological properties have not yet been explored. Monolaurin, for instance, is a naturally occurring substance whose use in human health has only been lately discovered.
Monolaurin, also called glycerol monolaurate and glyceryl laurate, is a 12-carbon fatty acid as well as a monoglyceride. Although it is a derivative of coconut oil, it is most commonly prepared as a lauric acid mono-ester. Aside from coconut milk, it is also present in human breast milk, which is known to function as an immune protection passed on from mother to child after childbirth. The potency of breast milk as an immune barrier is evidenced by the stunted growth and frequency of infections seen in infants deprived of breast milk. But, all this is old information.
What's new about monolaurin?
Known Uses of Monolaurin:
Before we get to new information, it's important to look into the discovery of monolaurin. Way back in the 1960's, then University of Detroit professor Jon Kabara made an important discovery - that the combination of lauric acid and glycerol can be used in fighting germs. First marketed as a dietary supplement called Lauricidin, it was soon marketed by other pharmaceutical companies, but Lauricidin remains its most potent and purest form.
Since its discovery, it has been used as symptomatic treatment (and prevention) for the common colds, flu, herpes, and many other infections.
Working similarly to breast milk, it helps protect the immune system from infections and other ailments. Some Lauricidin users also claim that the substance is useful against Chronic Fatigue Syndrome and even autism. As for viruses, it has proven to be a useful supplement against HIV, Measles, Herpes Simplex, Epstein-Barr Virus, and Cytomegalovirus, to name a few.
Recent studies have shown its in vitro antibacterial and antimicrobial activity, at least as far as superficial skin infections are concerned. Carpo, Verallo-Rowell and Kabara (2007) demonstrated the effectiveness of monolaurin versus common antibiotics in battling both gram positive and gram negative infections such as Staphylococcus and Enterococcus. Older studies have explained Monolaurin's mechanism of action - it inserts itself into the cell membrane, disturbs the cell membrane integrity of Gram positive bacteria, and therefore blocks cell replication.
Aside from medicinal uses, it is also used for other purposes as well. It is a common ingredient in many deodorants, thanks to its antimicrobial activity; body odor, as you may know, is caused by the presence of certain bacteria. It is also present in other products such as shampoo, detergents, soap, and even in certain foods such as ice cream and margarine.
Side Effects and Drug Interactions
As far as side effects are concerned, there is still a lot to be known. Some users may experience the Herxheimer Reaction, a complicated term that indicates the presence of fatigue, body ache, irritability and fever that may worsen before the medication takes effect. Use during pregnancy and breast feeding is contraindicated, given that not enough is known about its potential effects during this period. Dosage ranges from 0.75 to 3 grams, 2 or 3 times a day, and is taken after meals.
Can Melatonin Help Me Sleep?
December 20, 2012 12:22 PM
What is melatonin?
Melatonin can be described as a hormone generated in the pineal gland found in the brain. It controls the body circadian rhythms such as sleep-wake cycle. The levels of melatonin in the blood increase before you fall asleep due to darkness (Lack of sunshine).
Where to find melatonin
Melatonin occurs naturally in humans and plants. Natural melatonin quantity produced decrease with age. Older people produce very little quantities of it.
It is a synthetic medication that is produced in the laboratories. It is available in pill or liquid forms. The pills can be put in the cheek, underneath the tongue or swallowed. This permits direct absorption in the body. Melatonin supplements are available in health food shops.
It is also found in foods, in small quantities, such as milk, chicken meat, turkey, and peanuts but in small quantities.
Melatonin and sleep
Melatonin does not work for every kind of insomnia or sleeping disorders. Your body needs to be ready for sleep for melatonin to be effective. It is safe to use melatonin supplements in low doses long term.
Melatonin treats insomnia, autism in children, and as a sleep reliever after withdrawal from benzodiazepine drugs use. It is also very significant for changing sleep/wake patterns for people who work schedules changes regularly. It can also be used to calm individuals before anesthesia is administered for surgery purposes.
The body has an internal clock that regulates sleeping cycle and waking hours. The body clock regulates the amount of melatonin produced each day. Melatonin production is affected by light.
For effective treatment of cycle sleep, make sure you take the supplements at the appropriate time of the day (Night time).
Use the right method and dosage for it to be helpful.
Consuming the sleep supplement at the inappropriate time of the day can lead to biological clock reset. It is essential to understand the right quantity, time of taking and its effectiveness. Taking 1-10mg of melatonin every day restores the pace in people experiencing insomnia synchronizing them to duration of 1day.
Melatonin helps enhance sleep.
It enhances sleepiness feeling and can intensify the duration of sleep. This supplement has been applied successfully for improving sleep in healthy people and also decreasing jet lag feeling during travels. Remember to consult a physician if you are experiencing sleep issues. Give melatonin a try start with lower doses like 1 mg before bed time and gradually increase till it becomes effective.
November 17, 2012 10:35 AM
Vitamin D-3 has profound health benefits in our bodies.
It is necessary for maintaining bone density and the body's immunity against heart diseases, cancers, muscle wasting, osteoporosis, weakness, among other disorders. Like all the other types of vitamin D, Vitamin D-3 is a hormone which is produced naturally in our bodies. Very few foods contain this vitamin but the good thing is that it is readily available to the body via absorption of the rays of the sun.
Vitamin D-3 plays a crucial role in the development of the brain. Its deficiency in children may lead to autism. It also helps in the absorption of calcium which is needed for the development of bones. Children may also develop rickets which eventually cause bone deformities and results in weakening of the bones and muscles.
It also prevents per-eclampsia.
This is a condition that occurs during pregnancy and leads to production of protein in urine and high blood pressure, eventually leading to premature labor. Deficiency of Vitamin D-3 in the body poses numerous health risks. Since it is mainly manufactured in the skin directly from the sunlight, people living in areas with little sunlight are at an increased risk of suffering from the health problems that are caused by its deficiency.
People who stay in the northern climates are advised to take it through supplements in order to maintain their health. These supplements are available in health facilities and nutritional stores. The recommended intake of Vitamin D-3 is 1000 IU per day. This offers increased protection against mental illness, obesity, high blood pressure, osteoporosis and osteoarthritis.
This amount is easily produced by spending a few hours in the sunshine each week. Where sun exposure is not possible, vitamin D3 capsules will readily provide your body with these nutrients. These supplements are affordable and have no side effects to your body. They are necessary in order to ensure your body gets the required amount of Vitamin D3
Colostrum and immunity
June 17, 2009 10:13 AM
In order to obtain a smooth running immune system, communication between cells is absolutely essential. To communicate between cells, the system uses hormone-like signal substances, which can often be found in colostrum. It has been found in studies that an immune response can literally be transferred from a donor to another recipient by simply feeding that person with an extract of leucocytes. This extract contained a factor that was capable of passing on the donor’s immunity to the recipient. Scientists and researchers still do not know the exact constituents of colostrum, as colostrum extracts have been estimated to contain more than 200 individual compounds which each play a role in the communication process.
Because an immature response within the immune system to an infection can take anywhere from ten days to two weeks to completely develop, colostrum is essential because it can reduce this delay in reaction time due to two factors it possesses: an inducer/helper function, and a suppressor function. The inducer function allows the body to develop a mature response in as little time as twenty-four hours. However, an overactive immune response to agents that are always present like pollens and the body’s own cells is not healthy. The suppression factor comes in here, as it helps to control hyper-reactive responses that commonly turn into allergies and autoimmune diseases. Together, all of this helps to keep the immune system and the body’s overall health in a balanced state.
An infant’s first food is usually a mother’s milk, which is full of nutrient-rich colostrum. Colostrum contains valuable components which help the immune system to communicate and pass information between the cells. There are agents passed through colostrum that are not species-specific, meaning that they are equally effective in one species as they are in another. Additionally, this means that these agents generally do not cause allergies.
Colostrum and its derivatives can be used for many conditions including herpes, hepatitis, chronic fatigue syndrome, candidiasis, cancer, type I diabetes, intestinal injury, autism, rheumatoid arthritis, AIDS, and the Epstein-Barr virus. Herpes, which is a commonly found disease in today’s world that manifests itself in recurrent outbreaks which are characterized by sores and other skin lesions. Colostrum has been found to decrease the frequency of herpes outbreaks, as well as shortening the duration of any outbreak that is experienced. Agents found within colostrum are specifically programmed to fight the hepatitis viruses and are even able to prevent the onset of hepatitis.
Because colostrum and its immune agents are able to effectively help the body combat a variety of pathogens, it is also believed that colostrum can help to fight conditions like chronic candidiasis. Cancer may be prevented and fought with the use of colostrum and its various agents. Diabetes, which is one of the world’s most widespread and debilitating disorder, is increasingly associated with dysfunction of the immune system. Research has shown that colostrum and its compounds may have the ability to reverse diabetes. Colostrum has also been proven in studies to reverse the effects of autism on a child to the extent that the child can return to a mainstream school and participate in social activities. The Epstein-Barr virus, which is associated with symptoms including extreme fatigue and headaches, may be affected by colostrum, as studies have shown the total remission of symptoms in patients with this virus.
Colostrum is an amazing substance. Fortunately, it can be found at your local or internet health food store in capsule or tablet forms for easy consumption. Always purchase name brands like Source Naturals, Kal, and Now Foods to ensure quality and purity of the product you purchase.
May 02, 2009 11:41 AM
Methionine is an essential amino acid, meaning that it is not synthesized by the body, and so has to be taken as part of your diet. It also contains sulfur, one of two sulfur-containing amino acids that can form proteins, the other being cysteine. It is a precursor for taurine, which is an aminosulphonic acid, and not strictly an amino acid, which together with cysteine supports the health of your cardiovascular system and helps to eliminate toxins from the body.
Maintenance of Cell Membranes
It is also an important intermediary in the maintenance of cell membranes. Phospholipids are fat-soluble components of the cell membrane, phosphatidylcholine being a very important example. Also known as lecithin, this substance is derived from choline, itself biosynthesized in a chemical pathway involving S-adenosylmethionine.
This substance is made in the body from ATP (adenosine triphosphate) and methionine with the help of the enzyme methionine adensosyltransferase. Known as SAM (or SAM-e), S-adenosylmethionine employs a number of metabolic pathways in its reaction, though generally aminopropylation, transmethylation and transsulfuration. These add aminopropyl, sulfo and methyl groups to a number of substances, the most common being the methylation of proteins, nucleic acids and lipids.
Phosphatidylcholine is produced by the enzyme-catalyzed sequential methylation of phosphatidylethanolamine, SAM donating the methyl groups. The maintenance of the integrity of the cellular membrane by phosphatidylcholine is critical to all of the basic processes in human biology, including communication between cells, flow of information and bioenergetics.
A by-product of this reaction is homocysteine, formed in the liver from the S-adenosylhomocysteine that SAM is changed to after donating methyl groups. Excess homocysteine in the blood can create the risk of myocardial infarction and cardiovascular disease. SAM is also of use in the treatment of depression and of arthritis.
Creatine is a substance well known to athletes as being useful in provide short-term energy for high-intensity training. Although available in the diet, about 50% creatine used by the body is biosynthesized from methionine and two other amino acids, glycine and arginine. It allows a burst of energy lasting about 10 seconds, carried out without the use of glycogen reserves or fatty tissue.
Glycine and arginine combine to release ornithine as a by-product, and form guanidino acetate. SAM donates a methyl group to the latter to form creatine, about 95% of which is then stored in the skeletal muscle tissue. The stored creatine phosphate has the effect of allowing the muscle cells to hold more water, which also enables an enhanced level of protein synthesis, and hence an increase in muscle bulk, which also results from the increased blood flow resulting from the short-term high-intensity exercise that creatine allows.
Creatine can also increase the levels of MRF4 (myogenic transcription factor), resulting in an increasing in the myonuclei provided by satellite cells to damaged muscle tissue, that not only repair damaged muscle fibers, but also increase their ability to grow.
Detoxification of the Liver
Substances that help the liver to process fats, or lipids, are known as lipotropic, and the important lipotropics in human biochemistry are imositol, betaine, choline and methionine. They prevent fat from accumulating in the liver, and methionine is also useful in its effect of glutathione. This is a substance that helps the liver to neutralize toxins, such as excessive doses of acetaminophen, and its supplies are regulated by methionine.
Methionine and Autism
Research into autism is closely studying the Methionine/Glutathione Transsulfuration Pathway. This pathway is a very important biochemical means of detoxification, whereby toxins are methylated and then excreted. This pathway seems to be disrupted in autistic individuals.
Not only that, but disruption can lead to oxidative stress which results in many health problems. An example of this is the build-up of the oxidant homocysteine when there is insufficient Vitamin B6 to convert it into cysteine. This has been discussed previously, and is discussed again below.
Although research is in its infancy, it appears that AIDS sufferers also have decreased levels of methionine in their blood. It is believed that the process of AIDS could be linked to this, particularly the dementia that can occur as a result of the deterioration of the nervous system.
It is also hoped that it can help with some symptoms of Parkinson's disease, and pancreatitis. Initial research into this use of methionine has been very promising, as are studies into its use for urinary tract infections. It appears to operate like cranberry in this respect, preventing bacteria from attaching to the cell walls and multiplying in the urinary tract.
Methionine is believed to be essential for the formation of collagen, and for healthy pliable skin, hair, nails and other forms of connective tissue. For this reason it is often used as a supplement for the treatment of arthritis, although an excess should be avoided for reasons discussed above. S-Adenosylmethionine generates homocysteine during the biosynthesis of phosphatidylcholine, and this can cause cardiovascular problems.
So stick to the recommended doses when you use methionine as a supplement. Used properly, and according to instructions, it offers many health benefits, and can also be used to bulk up your muscle tissue and give increased energy when you need it most.
Dietary sources include fish, eggs, lentils, onions, garlic, meat, seeds, spinach and yoghurt. A good supplement would be from 800mg - 1000mg per day, and is best taken along with a B vitamin complex, or at least folic acid and vitamins B6 and B12, in order to prevent the increased generation of homocysteine.
Methionine also promotes the excretion of estrogen, so is a possible supplement for women on oral contraceptives that lower the production of this hormone. The elderly might also benefit from a supplement although, if taken for any specific condition, your health professional should be consulted first, as they should be for any supplement.
Nevertheless, methionine is a very useful supplement, and can be taken to prevent a large number of conditions. Research is continuing on its effect on AIDS patients, and Parkinson's, and it is hopeful that it will one day be recommended to help people suffering from these conditions.
August 07, 2008 06:03 PM
Probiotics are dietary supplements containing potentially beneficial bacteria for the small and large intestines. Probiotics, which means "for life", have been used for centuries as natural components in health-promoting foods. This beneficial bacterium is important in recolonizing the intestinal tract with good bacteria during and after antibiotic use as well as supporting overall health and wellness.
Probiotics are not the same thing as prebiotics which are non-digestible food ingredients that selectively stimulate the growth and/or activity of beneficial microorganisms already in the human colon. Probiotics are live microorganisms (in most cases, bacteria) that are similar to beneficial microorganisms found in the human gut. The use of good probiotics is important in healing many chronic gastrointestinal problems that are so often associated in those with autism spectrum disorder (ASD) and IBS.
One study performed in a 4-week, double-blind, placebo-controlled trial of 60 individuals with IBS, probiotics treatment with lactobacilli showed markedly beneficial to slowing down the bowels and reversing IBS. Two Scientific studies over the last 50 years show that probiotic organisms can improve the nutritional quality of foods, produce antibiotics, anti-carcinogens, and substances that break down and recycle toxins for their human host.
Historically, people used fermented foods like yogurt and sauerkraut both as food preservatives to limit spoilage, and to support their intestinal and overall health. Fermented foods such as sauerkraut also contain probiotics. Today probiotic bacteria such as Lactobacillus and Bifidobacterium are added by food manufacturers to fermented foodstuffs to improve their nutritional value.
There are, however, other foods that may contain added probiotics, such as sour cream, fruit juices and buttermilk. Food ingredient suppliers are now making it easier to add probiotics and prebiotics to foods and beverages by offering blends of synbiotics with the right proportion of pro- and prebiotics to obtain the desired beneficial health effects, as well as improved survival of the live bacterium strains.
Beneficial bacteria thrive and work with your digestive tract and immune system, along with Essential Fatty Acids, to protect you against illness and disease. It is also important to have a healthy balance of beneficial microbes to avoid sickness and disease and to keep your body stay nutritionally sound. Probiotic beneficial bacteria are involved in every aspect of your health. Along with beneficial bacteria, we show how supplements such as Essential Fatty Acids and Green foods provide the foundation for good health and provide a nutritional base for probiotics to grow and flourish in the body.
The most common form for probiotics are dairy products and fortified foods. Probiotics are products aimed at delivering living bacterial cells to the gut ecosystem of humans and other animals, whereas prebiotics are non-digestible carbohydrates delivered in food to the large bowel to provide fermentable substrates for the friendly bacteria to grow and thrive.
Probiotics are available to consumers mainly in the form of dietary supplements and foods. Because candida infection is very common due to overuse of antibiotics, several studies suggest that probiotics may be effective at preventing candida overgrowth as well as reversing it; candida is a good target pathogen for future probiotic research.
Although they are thought to be essential for health, because they can sustain themselves in the body under normal circumstances, there is no recommended daily intake of probiotics. By consuming foods with probiotics, you can increase the number of healthy bacteria, boost your immunity, and promote a healthy digestive system.
If you can not eat the foods that contain friendly bacteria, there are always probiotic supplements available from your local health food store. As always, it is best to check with your doctor or health care provider before starting any new supplements with medications. Probiotic formulas are a safe and effective means to deliver friendly bacteria to where it is needed, the colon.
Fight Stress With Magnesium Supplements
April 17, 2008 04:16 PM
When stress hormones are released into the body due to a stressful situation, several things may happen. Your metabolic rate can increase, heart rate jumps, blood vessels contract and get tighter, the rate at which one breaths gets more frequent and shorter, muscles contract in response to stress among other things.
At the cellular level a significant inflow of calcium decrease cellular magnesium to calcium ratios which stimulates cellular function such as secrete fluids, contract, go into active mode. The muscles prepare to contract this includes the lungs, heart, and blood vessels. Nerves start to fire more frequent, the blood gets ready to clot, and secondary stress hormones are released. Normally when the stress crisis is over, magnesium moves back into the cells at the cellular level forcing calcium out relaxing the cells, this allows the body to slow down and relax, the nerves calm down and blood flow slows.
Magnesium plays a vital role to relax the body, once the stressful situation is over. The demand for magnesium goes up with stress. If there are inadequate amounts of magnesium in the body, this magnesium deficiency can in itself sustain a stress response. A magnesium deficiency itself can initiate and maintain a stress response without a trigger to cause the stress in the first place. Low magnesium states can prevent the body from relaxing and cause muscle cramping. After a stressful situation, adequate magnesium is needed to help the body shift over to a relaxed state.
Boarder-line magnesium individuals can have a mental, emotional, environmental or physical state of continuous stress where their bodies never come down out of the stress state. This can be detrimental to health and wellness. Drinking coffee, alcohol, and eating lots of sugary foods will cause the body to become depleted. Today’s diets high in over processed foods are lacking magnesium; one should supplement by either changing ones diet or adding magnesium to their diet in mineral supplement form.
Symptoms of magnesium deficiency include signs such as, muscle cramps or twitches, insomnia, irritability, sensitivity to loud noises, anxiety, nervousness, autism, ADHD, heart palpitations, angina, constipation, spasms in the muscles, headaches, migraines, fibromyalgia, chronic fatigue, asthma and kidney stones (typically caused by a calcium-magnesium imbalance), diabetes, obesity, high blood pressure, menstrual cramps, irritable bladder, irritable bowel, acid reflux, and premenstrual syndrome, depression, low energy, weakness in the muscles, weakening bones (bone density loss), and calcification of organs.
Women who consume high amounts of calcium can actually create a greater deficiency in magnesium leading to greater bone mineral density lost then if no calcium was consumed at all. Foods today that are being fortified with calcium are actually helping women loose more bone density because magnesium is not in the right proportions.
To word off the negative effects of a prolonged or over-reaction to stress including a shortened lifespan, one needs to balance out their magnesium to calcium ratios by adding adequate amounts of both magnesium and calcium to their diet. Supplementing with 400 mgs to 800 mgs of elemental magnesium is critical for one looking to live a healthier longer life that is free from stress.
Keywords: Magnesium Deficiency, Fight Stress, Magnesium, Calcium, Fight High Blood Pressure
Description: Are you feeling tired, sick or maybe you feel like something is wrong but not quite sure what it is? Would you know if you had a magnesium deficiency? Magnesium is involved in over 300 enzymatic functions in the body; learn how it can help you!
Did You Know There Is One Mineral That Could Change Your Life Forever?
March 05, 2008 04:05 PM
Did you know there is one mineral that could affect the way you feel and change the way you live life forever? Yes that’s correct – forever - magnesium is that mineral! More than 50% of all Americans consume less then the required amounts of magnesium to stay healthy.
You might be wondering how you would know if you are deficient in magnesium and where you can get a test. Unfortunately it is not that simple. A magnesium test is available from your doctor, but when most people take this test, the results normally come back as normal, so we think everything is fine. This test only measures blood serum levels and not cellular magnesium. One needs to have their red blood cells tested to accurately measure the uptake of magnesium and at this time. This kind of testing needed is not readily available.
You might ask, “how can I tell whether I have a deficiency or not?” It is simple, look at your medical history. Symptoms of magnesium deficiency include signs such as, muscle cramps or twitches, insomnia, irritability, sensitivity to loud noises, anxiety, nervousness, autism, ADHD, heart palpitations, angina, constipation, spasms in the muscles, headaches, migraines, fibromyalgia, chronic fatigue, asthma and kidney stones (typically caused by a calcium-magnesium imbalance), diabetes, obesity, high blood pressure, menstrual cramps, irritable bladder, irritable bowel, acid reflux, and premenstrual syndrome, depression, low energy, weakness in the muscles, weakening bones, and calcification of organs.
If you did not notice, this is an extensive list of symptoms that may be attributed to a deficiency in magnesium. Magnesium is essential for cardiac function in stabilizing cardiac membranes preventing arrhythmias. This mineral helps the cardiovascular system relax aiding in the relief of angina symptoms. Millions of Americans are diagnosed with heart disease yearly, a magnesium deficiency may be the cause.
The reason we are deficient in magnesium is mostly due to the fact that we eat refined, over-processed foods with white flour that have absolutely zero magnesium. The consumption of foods not rich in magnesium will rob our bodies of the little we still have in our bones and organs. Drinking coffee, alcohol, eating lots of sugary foods and stress will cause the body to become depleted.
If you are experiencing one of the above mentioned symptoms and suspect you have a magnesium deficiency, changing they way you eat can help. Pick up a nutritional almanac and find foods high in magnesium like nuts, sea vegetables, dark leaf vegetables and beans to start. Also, kelp, wheat bran, wheat germ, buckwheat, millet, brown rice, rye, tofu, soybeans, brown rice, figs, dates, avocados, parsley, barley, dandelion greens and garlic all contains high amounts of magnesium. Adding a magnesium supplement to your diet which provides 200 to 400 milligrams per day will help. One should limit the intake of coffee, alcohol, colas, salt, and sugar. Actually, many medications can deplete the body of magnesium such as water pills (diuretics) and antibiotics to name two.
So now you know what to do, you might be thinking that a magnesium supplement would be the fastest way to boost magnesium in the body for the time being. What form of magnesium is best? The recommended form of magnesium is magnesium citrate, because of its digestibility and absorbability in the body. Avoid magnesium carbonate, sulfate, gluconate, and oxide if at all possible for these forms of magnesium are harder to digest and will result in smaller amounts being absorbed by the body. Now what are you waiting for, give magnesium a try and see how good you can feel from it!
Digestive Enzymes To Improve Wellness For Kids
November 04, 2007 03:19 PM
It is very safe to say that most people experience some type of digestive difficulty, as digestive disturbances are very common, especially for those who do not practice healthy eating. The numerous advertisements for antacids and acid blockers clearly identify the degree of this problem. But, what about our children? It has been proven that kids are suffering from digestive problems more than ever before due to unhealthy eating habits and nutritionally deficient diets that are high in saturated fats and processed sugars and carbohydrates. The food that is served in school cafeterias often contains too much fried food and not enough fresh produce. Additionally, parents have to constantly fight a losing battle against advertisements for junk food. Many children follow in the footsteps of their parents, picking up the same bad eating habits, which frequently leads to poor digestion and health problems. Overeating, eating too fast, or not chewing food well hinders digestive capability leading to symptoms such as gas, heartburn, bloating, burping, bad breath, diarrhea, constipation, and general discomfort or fatigue after meals. Although these symptoms are common, they should not be considered normal as they are distress signals sent by our body telling us that the digestive process is not going smoothly and we are not receiving the full nutritional benefit of the food we eat. If digestion is not efficient or complete, inflammation may develop, which causes “leaky gut syndrome,” leading to various allergic reactions.
The brain is especially susceptible to protein fragments, which come from the incomplete digestion of grain gluten and dairy casein. Researchers believe that these fragments, which are called exorphins, are the main factors in the cognitive symptoms and abnormal behaviors of those kids with ADHD and autism. A recent study on thirty-six autistic children found that a majority of these children had digestive disorders including esophageal reflux and inflammation, gastritis, duodenitis and low carbohydrate digestive enzyme levels. Some doctors believe that seventy-five percent of the children that they treat have major deficiencies of pancreatic enzymes.
Enzymes are often called the spark of life or the missing link in nutrition because no plant or animal can exist without them. Digestive enzymes are protein catalysts which break down food so the body can absorb nutrients. Therefore, enzyme supplementation can be extremely helpful, especially when it is done in conjunction with dietary changes. And, yes, kids can take enzymes supplements, too. In children with digestive symptoms, enzyme supplements help to establish proper weight because better assimilation of nutrients helps growth and repair while still supporting a healthy metabolism. Digestive enzymes come in mild-potency enzyme formula which covers all of the food groups for children. Children should take a powder which is safest so there are no caps to swallow and chock on and powdered enzymes allow children to get their digestive enzymes through one scoop which can be added to your child’s favorite juice. Some formulas add potassium carbonate, this form of potassium adds a fun fizz to whatever beverage is used, but is not recommended in milk or water. Look for a powdered supplement that is sweetened with xylitol, a safe and natural sugar substitute which supports tooth and gum health. Since more children than ever suffer from the consequences of incomplete digestion, digestive enzymes are a safe and effective way to support digestion and assimilation of important nutrients into your child’s diet in an enjoyable way.
TMG Fact Sheet
December 07, 2005 02:13 PM
TMG Fact SheetNeil E. Levin, CCN, DANLA 03/07/05
LIKELY USERS: People with high homocysteine levels; People with risks of developing Alzheimer’s Disease; People needing greater metabolism of fats; People with liver detoxification challenges; People consuming alcohol KEY INGREDIENTS: TMG is composed of three methyl groups attached to a glycine atom. It can “donate” methyl groups.
MAIN PRODUCT FEATURES: TMG is a metabolite of the B vitamin family product called Choline. Choline has 4 methyl groups, TMG has 3 and DMG has 2. These substances plus Folic acid, Vitamin B-12 and SAM-e are all methyl donors. Methyl donors can contribute methyl groups to biological processes such as liver function, detoxification and cellular replication (production of new cells). Methylation protects the kidneys and stimulates production of the fat-transporting molecule l-carnitine.
TMG helps the liver metabolize fats, preventing the accumulation of fats in the liver. It also helps to detoxify chemicals in the liver, while protecting the liver from being damaged by those chemicals.
Methylation with TMG helps to convert the dangerous, inflammatory chemical homocysteine into the amino acid methionine. TMG may lower homocysteine when B-6, B-12 and folic acid cannot.
ADDITIONAL PRODUCT INFORMATION: TMG is also known as Betaine and is a component of Betaine hydrochloride (Betaine HCl), a stomach acid supplement that is very acidic. But Betaine HCl is not used in the same way as TMG. TMG is not highly acidic and will not supplement low stomach acid.
TMG may be useful for autistic children, along with B-6 and magnesium. It may also be useful in strengthening the body’s immune response against pathogenic bacteria. There is very preliminary evidence that TMG and methyl donors may help against some forms of seizures.
DMG has been used as a sports supplement. TMG is 50% more effective than DMG in any application where the methyl groups are useful. Otherwise, they can used interchangeably.
SERVING SIZE & HOW TO TAKE IT: One serving per day, or up to 6,000 mg., as needed.
COMPLEMENTARY PRODUCTS: SAM-e, Milk Thistle (Silymarin), Dr. Verghese’s Liver Detoxifier & Regenerator, Antioxidants, NAC, Homocysteine Regulators, D-Flame, Detox Support
CAUTIONS: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement.
People with Parkinson’s or taking L-dopa should not use methyl donors like TMG without a physician’s specific approval and supervision. There are no other known drug interactions with TMG.
This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. This is not an official publication by any company, nor has this information been screened or approved by the FDA or any private company.
Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. REFERENCES:
Craig SA. Betaine in human nutrition. Am J Clin Nutr. 2004 Sep;80(3):539-49. Review. PMID: 15321791
Barak AJ, Tuma DJ. Betaine, metabolic by-product or vital methylating agent? Life Sci 1983;32:771-4 [review].
Benson R, Crowell B, Hill B, et al. The effects of L-dopa on the activity of methionine adenosyltransferase: relevance to L-dopa therapy and tolerance. Neurochem Res 1993;18:325–30.
Chambers ST. Betaines: their significance for bacteria and the renal tract. Clin Sci 1995;88:25-7 [review].
Charlton CG, Crowell B Jr. Parkinson’s disease-like effects of S-adenosyl-L-methionine: effects of L-dopa. Pharmacol Biochem Behav 1992;43:423–31.
Charlton CG, Mack J. Substantia nigra degeneration and tyrosine hydroxylase depletion caused by excess S-adenosylmethionine in the rat brain. Support for an excess methylation hypothesis for parkinsonism. Mol Neurobiol 1994;9:149–61.
Cheng H, Gomes-Trolin C, Aquilonius SM, et al. Levels of L-methionine S-adenosyltransferase activity in erythrocytes and concentrations of S-adenosylmethionine and S-adenosylhomocysteine in whole blood of patients with Parkinson’s disease. Exp Neurol 1997;145:580–5.
Crowell BG Jr, Benson R, Shockley D, Charlton CG. S-adenosyl-L-methionine decreases motor activity in the rat: similarity to Parkinson’s disease-like symptoms. Behav Neural Biol 1993;59:186–93.
Selhub J. Homocysteine metabolism. Annu Rev Nutr 1999;19:217-46 [review].
Brosnan JT, Jacobs RL, Stead LM, Brosnan ME. Methylation demand: a key determinant of homocysteine metabolism. Acta Biochim Pol. 2004;51(2):405-13. Review. PMID: 15218538 Gahl WA, Bernardini I, Chen S, et al. The effect of oral betaine on vertebral body bone density in pyridoxine-non-responsive homocystinuria. J Inherit Metab Dis 1988;11:291-8.
Olthof MR, van Vliet T, Boelsma E, Verhoef P. Low dose betaine supplementation leads to immediate and long term lowering of plasma homocysteine in healthy men and women. J Nutr. 2003 Dec;133(12):4135-8. PMID: 14652361
Olthof MR, Verhoef P. Effects of betaine intake on plasma homocysteine concentrations and consequences for health. Curr Drug Metab. 2005 Feb;6(1):15-22. PMID: 15720203
Schwab U, Torronen A, Toppinen L, Alfthan G, Saarinen M, Aro A, Uusitupa M. Betaine supplementation decreases plasma homocysteine concentrations but does not affect body weight, body composition, or resting energy expenditure in human subjects. Am J Clin Nutr. 2002 Nov;76(5):961-7. PMID: 12399266
Selhub J. Homocysteine metabolism. Annu Rev Nutr 1999;19:217-46 [review].
van Guldener C, Janssen MJ, de Meer K, et al. Effect of folic acid and betaine on fasting and postmethionine-loading plasma homocysteine and methionine levels in chronic haemodialysis patients. J Intern Med 1999;245:175-83.
Wendel U, Bremer HJ. Betaine in the treatment of homocystinuria due to 5,10-methylenetetrahydrofolate reductase deficiency. Eur J Pediatr 1984;142:147-50.
Wilcken DE, Wilcken B, Dudman NP, Tyrrell PA. Homocystinuria—the effects of betaine in the treatment of patients not responsive to pyridoxine. N Engl J Med 1983;309:448-53.
Wilcken DE, Dudman NP, Tyrrell PA. Homocystinuria due to cystathionine beta-synthase deficiency--the effects of betaine treatment in pyridoxine-responsive patients. Metabolism. 1985 Dec;34(12):1115-21. PMID: 3934499
Babucke G, Sarre B. Clinical experience with betain citrate. Med Klin 1973;68:1109-13 [in German].
Barak AJ, Beckenhauer HC, Badakhsh S, Tuma DJ. The effect of betaine in reversing alcoholic steatosis. Alcohol Clin Exp Res 1997;21:1100-2.
Barak AJ, Beckenhauer HC, Matti J, Tuma DJ. Dietary betaine promotes generation of hepatic S-adenosylmethioine and protects the liver from ethanol-induced fatty infiltration. Alcohol Clin Exp Res 1993;17:552-5.
Barak AJ, Beckenhauer HC, Tuma DJ. Betaine, ethanol, and the liver: a review. Alcohol 1996;13:395-8 [review]. PMID: 8836329
Freed WJ. Prevention of strychnine-induced seizures and death by the N-methylated glycine derivatives betaine, dimethylglycine and sarcosine. Pharmacol Biochem Behav. 1985 Apr;22(4):641-3. PMID: 2581277
Junnila M, Barak AJ, Beckenhauer HC, Rahko T. Betaine reduces hepatic lipidosis induced by carbon tetrachloride in Sprague-Dawley rats. Vet Hum Toxicol 1998;40:263-6.
Ji C, Kaplowitz N. Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice. Gastroenterology. 2003 May;124(5):1488-99. PMID: 12730887
Kettunen H, Tiihonen K, Peuranen S, Saarinen MT, Remus JC. Dietary betaine accumulates in the liver and intestinal tissue and stabilizes the intestinal epithelial structure in healthy and coccidia-infected broiler chicks. Comp Biochem Physiol A Mol Integr Physiol. 2001 Nov;130(4):759-69. PMID: 11691612
Kim SK, Kim YC, Kim YC. Effects of singly administered betaine on hepatotoxicity of chloroform in mice. Food Chem Toxicol 1998;36:655-61.
McCarty MF. Co-administration of equimolar doses of betaine may alleviate the hepatotoxic risk associated with niacin therapy. Med Hypotheses. 2000 Sep;55(3):189-94. PMID: 10985907
Murakami T, Nagamura Y, Hirano K. The recovering effect of betaine on carbon tetrachloride-induced liver injury. J Nutr Sci Vitaminol 1998;44:249-55.
Poschl G, Stickel F, Wang XD, Seitz HK. Alcohol and cancer: genetic and nutritional aspects. Proc Nutr Soc. 2004 Feb;63(1):65-71. Review. PMID: 15070439
Semmler F. Treatment of liver diseases, especially of fatty liver with betaine citrate. Ther Ggw 1977;116:2113-24 [in German].
Zapadniuk VI, Panteleimonova TN. [Cholagogic effect of trimethylglycine in normal animals of different ages and in experimental atherosclerosis] Biull Eksp Biol Med. 1987 Jul;104(7):30-2. Russian. PMID: 3620644
Autism & Seizures:
Rimland B. Seizures, Vitamin B6, DMG, and Sudden Speech. Autism Research Review International. 1996;10(2):1.
Roach ES, Carlin L. N,N-dimethylglycine for epilepsy. N Engl J Med. 1982;307:1081-82.
Vitamin B6/DMG. Letters to the Editor, Autism Research Interview International. 1994;8(2):6.
Reap EA, Lawson JW. Stimulation of the immune response by dimethylglycine, a nontoxic metabolite. J Lab Clin Med. Apr1990;115(4):481-6.
Hoorn AJ. Dimethylglycine and chemically related amines tested for mutagenicity under potential nitrosation conditions. Mutat Res. 1989 Apr;222(4):343-50. PMID: 2468082