Search Term: " Curcuma "

	Turmeric Vs Curcumin?	Darrell Miller	9/18/20
	Turmeric & Curcumin Benefits: Can This Herb Really Combat Disease?	Darrell Miller	1/25/19
	Scientists study the neuroprotective effects of fermented Curcuma longa L. (turmeric)	Darrell Miller	7/4/18
	Interaction of turmeric (Curcuma longaL.) with beneficial microbes	Darrell Miller	10/9/17
	Give your healthy diet a boost with supplements - USA TODAY	Darrell Miller	8/27/17
	Adaptogens for a Stressful World	Darrell Miller	8/16/17
	What Are The Benefits Of Turmeric Extract?	Darrell Miller	6/4/13
	What Herbs Are Good For Boosting The Immune System?	Darrell Miller	3/25/12
	How Does Curcumin Reduce Inlammation In The Body?	Darrell Miller	3/15/12
	Turmeric, Curcumin, And Good Health	Darrell Miller	11/11/10
	Fight Inflammation With Herbs from Planetary Herbals	Darrell Miller	6/2/10
	Fight Inflammation With Inflama-Care - Anti-inflammatory herbal combination	Darrell Miller	3/22/10
	Turmeric Extract (Curcumin)	Darrell Miller	2/10/09
	Turmeric and Alzheimer’s Disease	Darrell Miller	5/10/07
	Complete Liver Cleanse	Darrell Miller	4/19/07
	Benefits - Supports joint function and tissue health*	Darrell Miller	12/11/06
	Degenerative joint disease (osteoarthritis)	Darrell Miller	8/24/06
	Goes above and beyond antioxidant protection.	Darrell Miller	2/10/06
	Allibiotic CF Fact Sheet	Darrell Miller	12/7/05
	Curcumin - Turmeric Extract	Darrell Miller	8/19/05
	The Flex Factor	Darrell Miller	6/11/05
	MYELIN SHEATH SUPPORT™ - Herbal-Nutrient Nervous System Support!	Darrell Miller	6/4/05

Date: September 18, 2020 02:50 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Turmeric Vs Curcumin?

Turmeric "Curcuma longa" is the plant that has been a part of Indian and Asian cuisine and medicine for thousands of years. Turmeric rhizomes like the root of the plant contain compounds called curcuminoids. This family of compounds is called (Curcumin), and has been shown to have powerful benefits for the brain, heart, cellular immune response, and healthy inflammation response in numerous clinical studies around the world.*

So in a nutshell, Turmeric is the "whole Root" and Curcumin is a compound in the root that does all the heavy lifting to fight inflammation, improve immunity, benefits the heart and brain, ect. Look for a supplement that is standardized to the curcumin to ensure bang for the buck.

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Date: January 25, 2019 10:22 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Turmeric & Curcumin Benefits: Can This Herb Really Combat Disease?

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Date: July 04, 2018 05:54 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Scientists study the neuroprotective effects of fermented Curcuma longa L. (turmeric)

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Date: October 09, 2017 01:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Interaction of turmeric (Curcuma longaL.) with beneficial microbes

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Date: August 27, 2017 09:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Give your healthy diet a boost with supplements - USA TODAY

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Date: August 16, 2017 09:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Adaptogens for a Stressful World

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Date: June 04, 2013 01:53 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Are The Benefits Of Turmeric Extract?

Turmeric extract, also known as Curcuma longa has been used for over 4000 years to treat a variety of conditions. Reputable studies show that it may help control infections, reduce inflammation, and treat digestive problems and some cancers. Historically, it has been widely used in cooking Indian dishes and is much loved due to its curry flavor and yellow color.

Further, it's used to color butter and cheese and has been intensively applied in both Chinese and Ayurvedic medicine to treat wounds and skin diseases.

According to research done at the University of Maryland Medical Center, turmeric extract contains powerful ingredients that stimulate the production of bile and thus can be used to control indigestion.

Let us take a more straight forward look at its main benefits to human health.

Benefits of Turmeric Extract

* Fighting inflammation

Turmeric contains a special substance called curcumin which aside from destroying free radicals lowers the levels of some enzymes in the body that fuel inflammation. Clinical studies have suggested that turmeric's duo benefits (antioxidant and anti-inflammatory) are an essential part of recovering from joint stiffness - useful in relieving rheumatoid arthritis.

* Indigestion

As we mentioned earlier, turmeric can boost the production of bile. One double-blind study (done by The German Commission E) concluded that turmeric may help in improving the functioning of the digestive system by reducing bloating.

* Turmeric and ulcerative colitis

Although turmeric does not seem to help control stomach ulcers, researchers at the University of Maryland Medical Center confirm that can play a central role in people with ulcerative colitis by helping them stay in remission. Recent studies done on people with this disease (who consumed turmeric) showed a lower relapse rate than who took other treatment substances.

* Turmeric extract and cancer

Though most results are still early, there has been a great deal of findings that have painted turmeric in good light as far as treatment of various cancers is concerned. At the moment, scientists are keenly studying its effects on colon, skin, breast and prostate cancers. All the same, turmeric is known for its preventive effects which have something to do with its strong antioxidant properties.

* Turmeric=Good Heart Health

Some substances found in turmeric extract may help reduce incidences of atherosclerosis - a condition closely associated with the occurrence of stroke and/or heart attack. It, in a great way lowers cholesterol levels in blood vessels. Aside from that, it stops platelets from clumping together thus preventing blood clots from accumulating along blood vessels.

* Containing Viral and Bacterial Infections

Turmeric may to some extent kill viruses and bacteria. Some of its active ingredients are as well known to expel intestinal worms.

* Uveitis

Turmeric has been for a long time been associated with good eye health. Well, researchers have recently made breakthrough findings that curcumin (turmeric's main active ingredient) may help treat chronic anterior uveitis. Its efficiency is believed to be at par with corticosteroids.

There are many other health benefits associated with turmeric extract. However, the few mentioned herein are the most important ones that you need to take note of.

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Date: March 25, 2012 03:11 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Herbs Are Good For Boosting The Immune System?

Herbs for Immunity

The immunity system comprises a network of organs, cells and tissues that are responsible for your overall wellness. The status of your immunity system mainly depends on your feeding habits. The foods you eat supply you with vital nutrients and minerals that help protect you from diseases. The white blood cells in your body are also endowed with the role of defending your body against diseases. There are herbs that help increase the number of white blood cells, while others produce immunity cells thus boosting your immunity system. The following are the best herbs that are good for boosting the immune system:

Astragalus

Astragalus is a traditional Chinese herb that is locally known as Huang-Qi. The roots of this herb are used for a wide range of purposes, one of which is to boost the immune system. This is because of its ability to increase the number of T-cells and interferon.

Astragalus is also used to treat inflammatory conditions, liver problems, viral and bacterial infections, lack of appetite, short breath, stomach ulcers, flu, common cold, diabetes, stress, hypertension and body weakness. This herb also interferes with the growth of cancerous tumors, and has thus been used as a natural aid during chemotherapy treatments.

Echinacea

Echinacea is a group of herbs popular within the American market, which are also known as black susans, Indian head, American cone flower, or Kansas snake root. The popular species of Echinacea are E. pallid, E. purpurea and E. angustifolia.

These herbs have been used for ages as natural immune boosters because of their ability to increase the number of WBC as well as spleen cells in your body. They also increase the number of natural immune chemicals such as immuno globin, interferon and interleukin. When White Blood Cells increase, they give your body maximum protection against antigens that interfere with your overall wellness. The phenolic compounds found in the flowers, roots and leaves of Echinacea herbs are the ones that facilitate this immuno stimulating function.

They are also natural remedies for common colds, respiratory infections, skin complications and Urinary tract infections. These herbs can suppress your immunity if taken habitually. Therefore, it is recommended that you use the herb only when you suspect infection. It is also advisable for you to limit the intake of Echinacea to a week because overuse may generate unbearable symptoms.

Golden seal

This herb is also known as Ground Raspberry, Yellow Root, Orange Root, Wild Curcuma, Indian Dye, Indian Paint, Jaundice Root or Indian Plant. It is a medicinal herb that contains berberine, canadine and hydrastine alkanoids. Golden seal also contains vital vitamins and minerals that are needed for strong immunity system.

One of the benefits of Golden Seal is that it serves as an immuno stimulant, especially when blended with echinacea. It has also been used to treat various medical conditions such as inflammation, herpes and common cold. It also has tonic and antiseptic qualities. You can also use it externally to cure sores and itchy sensations.

So if you want an immune boost, give one of these herbs a try!

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Date: March 15, 2012 07:53 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How Does Curcumin Reduce Inlammation In The Body?

Curcumin Health Benefits

Curcumin is an active component in turmeric plant (Curcuma Longa) and it is the component that gives yellow color in turmeric plant. The concentration of this component in turmeric plant is around 2-5%. Turmeric plant is a rather tall plant and it is mainly grown in India and other Asian countries.

For centuries, Curcumin has been used for Ayurveda, Chinese herbal medicine, and other Asian traditional medicine due to its various healing properties and low side effects. Besides being used for traditional medicine, this natural component is also used to increase energy, aid digestion, and reduce inflammation in the body.

The modern medical research of curcumin started in 1910. Since then, this turmeric's component is researched extensively by scientists worldwide to find its various health benefits. The followings are some of the benefits of curcumin and an explanation on how this natural component can help to reduce inflammation in the body.

Benefits of Curcumin

Many medical studies have shown that Curcumin has many benefits for human health. The first benefit is to cure digestive disorders. This natural component improves digestion by stimulating bile production in the gallbladder. Naturally, an increase in bile production can worsen stomach ulcers symptoms but many studies show that when the curcumin increases the bile production, it also reduce so stomach ulcers symptoms.

Benefits two

The second benefit of Curcumin is to cure heart disease. Heart attack occurs because there is atherosclerosis, the buildup of plaque that can block arteries. Curcumin helps people with heart disease by preventing the development of atherosclerosis. Many studies also show that this natural component is also helpful to lower cholesterol level in the body.

Another important benefit of this natural component is to cure cancer. This natural component has anti-cancer properties and many studies have shown that it can cure various types of cancers such as colon, skin, breast, and prostate cancer. It is able to limit the number of blood flow to the malignant tumors so the growth of cancer can be stopped.

How Curcumin reduces inflammation in the body

There are many ongoing studies that analyze the benefits of Curcumin to reduce inflammation. However in a 2006, a study has shown that this natural component is able to prevent joint inflammation in arthritis. The study shows that to reduce inflammation in the body, curcumin stops platelets from coagulating into blood clots and lowers the amount of two inflammatory enzymes, LOX and COX-2. Unfortunately, the study recommends consuming turmeric and not just the curcumin extract because turmeric has other properties that are helpful to reduce inflammation.

Considerations

Curcumin can easily be found in market as a spice but today it is also available in dietary supplement. Although it is safe to be consumed, there are several side effects that might occur after consuming this natural component such as diarrhea, nausea, upset stomach and heartburn. People who have gallbladder problems are recommended to avoid it because this natural component can induce gallbladder contraction. Pregnant women are also not recommended to consume it because it is a mild uterine stimulant. curcumin can be found under names like curamin, or turmeric at your local vitamin store.

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Date: November 11, 2010 03:48 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Turmeric, Curcumin, And Good Health

Turmeric and its history

Turmeric, because of its Curcumin content, has many health benefits to humans. Firstly, Turmeric has an anti-inflammatory property. Its active ingredient, Curcumin, has been proven to help reduce inflammation. Decade to decade, Turmeric has been used as an anti-inflammatory agent to treat inflammations of the skin and muscles. Experiments done by researchers also revealed that this herb has been effective in decreasing post-surgical inflammation. This important health benefit of Turmeric is considered to be a result of the herb’s ability to slow down, if not to totally stop, Eicosanoid Biosynthesis, one of the processes the immune system undergoes during an inflammatory response.

Secondly, as a result of its anti-inflammatory characteristic, Turmeric also has an anti-arthritic property. It is widely used as an alternative medicine for rheumatoid arthritis and other autoimmune disorders. In addition, this herb also has a natural painkiller effect. Studies show that it has similar actions to the commonly used medications such as COX-2 inhibitor and Nonsteroidal Anti-inflammatory Drugs.

Thirdly, several studies have shown that Turmeric is also helpful in lowering the level of bad cholesterol in the blood known as the Low Density Lipoprotein or LDL and in increasing the body’s good cholesterol, High Density Lipoprotein or HDL. An increased level of LDL promotes cholesterol plaque deposits to the walls of blood vessels, most commonly in the arteries of heart. These plaques narrow the arterial diameter hence resulting to high blood pressure and even circulation blockage. An arterial block may cause poor circulation and oxygenation to heart muscles leading to cardiac injury then infarction. This is oftentimes the cause of heart attacks. It has also been discovered that Turmeric can promote excretion of dietary fats. Thus, controlling the intestinal uptake of fats, especially cholesterol.

Turmeric - Powerful Antioxidant

This herbal plant can be prepared in the household by pounding and pressing its roots to be able to extract the juice out. It is then mixed with water and may be used topically or by nasal inhalation. The root can also be lightly cooked and eaten. Turmeric is also helpful in earaches and to clear clogged sinuses thus easing breathing. This herb can also be purchased in bulk powder or standardized forms to ensure its beneficial properties are intact.
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Date: June 02, 2010 04:39 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Fight Inflammation With Herbs from Planetary Herbals

Our modern lives have untold benefits, as well as challenges. Our dependence on man-made toxic chemicals, junk food, nutrient imbalanced diets, and our stressful, sedentary lifestyles can alter our biochemical metabolism and affect our health.

These lifestyles and environmental change can challenge immune health, so that the various components of the immune system are not able to carry out their protective functions. Or our immune systems can go into overdrive, often leading to a state called metabolic inflammation.

A Powerful Herbal Blend

Inflamma-Care is a potent, herbal response to the metabolic inflammation that can result from inappropriate immune response. The main component of inflama-care is the rhizome of the Curcuma spicies, long used as a spice in India. Known worldwide as turmeric (Curcuma longa), it acts as an anti-inflammatory by inhibiting the activities of cytokines – inflammation messengers.

This world-renowned spice is supported by boswellia, which inhibits pro-inflammatory enzymes, and ginger an antioxidant that inhibits prostaglandin and leukotriene biosynthesis. Other herbs in the formula that inhibit inflammatory action include willow bark, Chinese skullcap, corydalis, holy basil, and hops.

Inflama-care also contains systemic enzymes to clear and protect the arteries and circulatory system. Systemic enzymes like bromelain and papain cleanse the bloodstream and enable the blood to flow smoothly. A free-flowing bloodstream helps the body by circulating important nutrients to the cells while clearing the body of wastes.

Immune Activating Mushroom

Planetary Herbals also offers you new Full Spectrum Chaga in 1000mg tablets and a 1:4 liquid extract. Preliminary studies suggest that chaga triggers immune responses and protects the cells with antioxidant activity.

Chaga is a mushroom that is found attached to trees like birch, alder, beach, and other hardwoods, throughout the northern latitudes. A polyphore, the mushroom looks somewhat like coal – a brownish black mass often seen in tree trunks. In China, Siberia, Finland, Japan, Poland and North America, ancient and native peoples have long known the benefits of chaga. In an acient treaties, the Chinese monk shen nog declared in 100 BC that chaga is “a precious gift of nature.”

In modern research, chaga has been shown to have 215 phytonutrients, including 29 beta-glucans. Chaga also absorbs a nutrient from the outer birch tree bark: betulin, a natural anti-inflammatory. Among the components in chaga are triterpenes, sterols, beta-glucans, flavonoids, melanins, polyphenols, saponins, lignin, amino acids, vitamins, minerals, and fiber. This fascinating combination of nutrients is being studied worldwide.

The PhytoDynamic Difference

Both inflama-care and full spectrum chaga are formulated with a profound understanding of the ways in which plant compounds interact with human physiology. Planetary Herbals phytodynamic principles draw on herbal tradition, scientific research, and a level of clinical expertise unmatched in the natural products industry. The result: herbal products unsurpassed for quality and consumer satisfaction.

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Date: March 22, 2010 09:07 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Fight Inflammation With Inflama-Care - Anti-inflammatory herbal combination

Turmeric / Boswellia Complex

Our modern lives have untold benefits, as well as great challenges. Our dependence on man-made toxic chemicals, junk food, nutrient-imbalanced diets, and our stressful, sedentary lifestyles can alter our biochemical metabolism and affect our health. These unhealthy lifestyles and environmental changes have set our immune system on overdrive, a state call metabolic inflammation. Planetary Herbals Inflama-Care is a potent, herbal response to these modern challenges.

The Inflammation Cycle

As toxins and stress begin to alter our body chemistry and change the function of vital tissues, our body reacts with metabolic inflammation just as if it were being attacked. This reaction may result in a perpetual cycle of chemical imbalances and suboptimal health. Yet metabolic inflammation is often below the threshold of perception, not noticed or felt for years after its starts. It is only much later that the altered biochemistry and the system imbalances that it generates are noticed.

A Powerful Herbal Blend Inflama-Care helps support the body’s natural response to metabolic inflammation. The main component of the formula is the rhizome of the Curcuma species, long used as a spice in India. Known worldwide as turmeric (Curcuma longa), it acts as an anti-inflammatory by inhibiting the activities of cytokines—inflammation messengers. This world-renowned spice is supported by boswellia, which inhibits proinflammatory enzymes, and ginger, an antioxidant that inhibits prostaglandin and leukotriene biosynthesis. Other herbs in the formula that inhibit inflammatory action include willow bark, Chinese skull cap, corydalis, holy basil, and hops.

The PhytoDynamic Difference

Planetary Herbals presents inflama-Care to help maintain the body’s biochemical balance and integrity. Inflama-care was formulated with a profound understanding of the ways in which plant compounds interact with human physiology. Planetary Herbals phytodynamic principles draw on herbal tradition, scientific research, and a level of clinical expertise unmatched in the natural products industry. Thie result: herbal products unsurpassed for quality and consumer satisfaction.

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Date: February 10, 2009 01:18 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Turmeric Extract (Curcumin)

Curcumin is a potent antioxidant and anti-inflammatory that has the potential to provide far-reaching health benefits. It has been shown to be helpful in rheumatoid arthritis, inflammatory bowel disease, pancreatitis, Alzheimer’s disease, heart disease, diabetic retinopathy, and cancer. All of these diseases share underlying inflammation that curcumin may help to diminish.

If you have ever eaten curry or cooked with the spice turmeric, you’ve consumed curcumin. It is obtained from the roots of Curcuma longa and consists of several curcuminoids. Turmeric is biologically related to ginger. Curcumin works as an antioxidant, boosting levels of glutathione S-transferase, which is one of the body’s principal antioxidants. This antioxidant blocks the formation of prostaglandin E2, which is a compound that promotes inflammation within the body. Curcumin also inhibits two inflammation-promoting enzymes: COX-2 and 5-LOX. Additionally, curcumin is able to prevent mutations to DNA, which is an effect that helps to maintain younger, healthier cells.

A study conducted at the University of Arizona Health Sciences Center in Tucson had researchers using a curcumin rich turmeric extract to treat rheumatoid arthritis in laboratory animals. The extract blocked joint inflammation as well as the breakdown of joint cartilage and bone. It did this by inhibiting the genes that are involved in inflammation. Curcumin also holds tremendous promise in preventing cancer, as well as an adjunct treatment. Studies on animals have found that curcumin can protect against colon, intestinal, oral, and skin cancers. Its benefits come from several mechanisms. First of all, it blocks the cell-growth cycle in cancer cells, which eventually leads to destruction. It also reduces free radicals and inflammation, both of which can lead to cancer-causing cell mutations.

Many studies have found that curcumin can protect the liver against a variety of toxic compounds, which is important news for those people who are suffering from liver diseases like hepatitis or cirrhosis. In a recent study, researchers reported that curcumin increased the clearance of creatinine and urea, which are signs of improved kidney function. Additionally, curcumin reduced liver damage from toxic chemicals and excess iron.

Another study found that curcumin has the ability to inhibit the activation and spread of the liver cells that play a role in the development of cirrhosis. Japanese doctors have recently used curcumin, drugs, or placebos to treat 89 patients that have ulcerative colitis. These doctors found that a combination of curcumin and conventional medications resulted in the greatest benefits over six months of treatment. Patients in this study took 1,000 mg of curcumin after breakfast and again after dinner.

Inflammation is the underpinning of all chronic degenerative diseases, making curcumin likely to be beneficial for many different conditions. So far, research has identified curcumin’s benefits for diabetic retinopathy, lung disorders, and skin problems such as psoriasis. A dose of 3.6 g of curcumin reduced PGE2 levels by two-thirds in only one hour. After consuming curcumin daily for one month, PGE2 levels were 57 percent lower than before supplementation began.

Turmeric has been used as a culinary spice for at least 2,000 years. It was listed in an Assyrian herbal in 600 BC, used by ancient Greeks, and widely recommended in Ayurvedic medicine. Native to India and other regions of South Asia, it may reduce the risk of Alzheimer’s disease and help maintain mental function. Curcumin is safe in amounts of 500 to 8,000 mg daily, with most supplements providing 500 mg of curcumin.

Turmeric has been proven safe in larger amounts, but is usually limited by taste as a spice. One should look for a standardized supplement that contains at least 90 percent curcumin. Standardized Turmeric can be found at your local or internet health food store.

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Buy Turmeric at Vitanet ®, LLC

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Date: May 10, 2007 12:38 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Turmeric and Alzheimer’s Disease

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Date: April 19, 2007 04:17 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Complete Liver Cleanse

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Buy Liver Cleanse Supplements at Vitanet

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Date: December 11, 2006 03:46 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Benefits - Supports joint function and tissue health*

To understand glucosamine's role, it is important to understand joint structure and function. Cartilage in the joints acts as a shock absorber to cushion the blows of daily wear and tear. Joint cartilage is made of a unique connective tissue that consists of collagen and proteoglycans. Collagen is a strong, fibrous, insoluble protein. Proteoglycans are large, carbohydrate-rich protein chains made up of 95 percent polysaccharides and 5 percent protein called glycosaminoglycans (GAGs). GAGs are composed of repeating two-sugar units (disaccharides) that contain glucosamine sulfate and other amino sugars. Surrounding the joint cartilage is synovial fluid, which contains many substances including its chief component, hyaluronic acid. Hyaluronic acid forms the backbone of other proteoglycans and is responsible for the thickness of synovial fluid as well as its lubricating and shock-absorbing properties. Synovial fluid also provides nutrients for the joint cartilage.

Glucosamine sulfate is a normal constituent of glycosaminoglycans in cartilage and synovial fluid. In essence, glucosamine sulfate provides important building blocks for cartilage production. Laboratory studies suggest that glucosamine may also function to stimulate production of cartilage-building proteins. It is also thought that the sulfate portion of the molecule contributes to the efficacy of glucosamine sulfate in the synovial fluid by providing the elemental sulfur needed for strengthening cartilage and aiding glycosaminoglycan synthesis. 1,2,3

Glucosamine sulfate has been the subject of research for over twenty years. Clinical trials as well as experimental studies have repeatedly supported the efficacy of oral glucosamine sulfate in supporting joint function. In one large open trial, over 1200 people took oral glucosamine sulfate for periods ranging from 36 to 64 days. In this multi-center trial, ninety-five percent of the subjects experienced greater joint comfort and increased mobility. The physicians reported "good" results in 59%, and "sufficient" results in 36%. Furthermore, the improvements in joint health lasted for up to three months after the glucosamine sulfate was discontinued. 3

Promotes optimal joint comfort, function and flexibility*

Boswellia serrata (Indian frankincense) has been used for centuries in the Indian Ayurvedic system of medicine to maintain healthy joints. Even today, this is one of the primary uses for this plant in Ayurvedic medicine. Boswellic acids have been shown to support healthy joint tissue, maintain circulation to joints, enhance joint mobility, and promote joint comfort in animal models without known side effects. 4

Boswellin® is an extract rich in boswellic acids. Boswellic acids are potent modulators of enzymes involved in leukotriene synthesis in vitro, promoting a healthy balanced production of these components of the immune system.5 Healthy leukotriene balance can lead to enhanced joint function. A human clinical study was conducted to assess the effects of supplementation with a formula containing Boswellia, Curcumin and other nutrients on joint function. In this double-blind placebo-controlled crossover trial, participants were randomly assigned to receive the herbal formulation or a placebo for 3 months. Following this 3-month period, the treatments were reversed for an additional 3 months. The results showed that while each group was receiving the herbal formulation, they had superior joint function and a greater sense of joint comfort when compared to the placebo groups.6 Other trials lend further support to Boswellia’s ability to promote healthy joint function.4,6,7

Curcumin is a potent antioxidant that has known free radical scavenging activity. This activity of Curcumin is thought to play a major part in its role as a joint protective nutrient. In fact, the numerous beneficial effects attributed of whole turmeric are thought to stem in large measure from the antioxidant properties of curcuminoids. Antioxidants neutralize free radicals, which are highly unstable molecules that can damage cellular structures through abnormal oxidative reactions. Curcumin is not toxic to cells, even at high concentrations. Pure Curcumin was shown to be less protective than a mixture of curcuminoids, indicating a possible synergism among the curcuminoids.8

Curcumin demonstrates several other in vitro effects linked to free radical scavenging. Curcumin scavenges nitric oxide, a compound associated with the body’s inflammatory response.9 Curcumin also demonstrates in vitro inhibition of certain enzymes involved in promoting inflammatory reactions in the body. Together these results strongly suggest that Curcumin is a potent bioprotectant with a potentially wide range of therapeutic applications.9,10,11

Preliminary human trials have assessed the therapeutic potential of Curcumin, with results that verify the traditional use of turmeric as an herb to enhance joint health. In a short-term double-blind, cross-over, comparative study, eighteen people were randomized to receive Curcumin (1200 mg daily) or an alternative therapy for two-week periods. The participants in the Curcumin groups were shown to produce measurable enhancements in joint flexibility and walking time.12 Research suggests that Curcumin and Boswellia work extremely well in combination to benefit joint health and mobility, as trials combining both nutrients have yielded highly positive results.

Bioperine-Nature’s Absorption Enhancer Boosts Nutrient Absorption*

Traditional Ayurvedic herbal formulas often include black pepper or long pepper as synergistic herbs. The active ingredient in both black pepper and long pepper is the alkaloid, piperine. Experiments carried out to evaluate the scientific basis for the use of peppers have shown that piperine significantly enhances bioavailability when consumed with other substances.13 Several double-blind clinical studies have confirmed that Bioperine® increases absorption of nutrients.14

Curcumin is known to be poorly absorbed in the intestinal tract when used on its own, thereby limiting its therapeutic effectiveness. Oral doses are largely excreted in feces, and only trace amounts appear in the bloodstream. However, a study has shown that concomitant administration of 20 mg of piperine with 2 grams of Curcumin was able to enhance Curcumin bioavailability by an astounding 2000%. 15 These results speak to the wisdom of including a small amount of Bioperine® in the formulation to ensure nutrient bioavailability.

Sustained Release – For lasting joint comfort and convenient dosing

To ensure that the body can utilize all of the joint health-enhancing nutrients effectively, Best Joint Support featuring ArthriBlend-SR™ has been designed to have a sustained release delivery system. The nutrients are released over a longer period of time, maximizing absorption and providing the comfort-enhancing properties in a sustained manner. This unique delivery system allows the product to be taken just twice daily while maintaining its efficacy throughout the day.

Safety

Suggested Adult Use: Take two tablets every 12 hours. Take 4 tablets daily.

Scientific References
1. Vidal y Plana, R.R., Bizzarri, D., Rovati, A.L. Articular cartilage pharmacology: I. In vitro studies on glucosamine and non-steroidal antiinflammatory drugs. Pharmacological Research Communications 1978; 10(6):557-569.

2. Tapadinhas M.J., Rivera, I.C. Bignamini, A.A. Oral glucosamine sulphate in the management of arthrosis: report on a multi-centre open investigation in Portugal. Pharmatherpeutica 1982; 3(3):157-68.

3. Vaz, A.L. Double-blind clinical evaluation of the relative efficacy of ibuprofen and glucosamine sulphate in the management of osteoarthrosis of the knee in out-patients. Current Medical Research and Opinion 1982; 8(3):145-149.

4. Kimmatkar N, Thawani V, Hingorani L, Khiyani R. Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee--a randomized double blind placebo controlled trial. Phytomedicine. 2003 Jan;10(1):3-7.

5. Safayhi, H., Mack, T., Sabieraj, J., Anazodo, M.I., Subramanian, L.R., and Ammon, H.P.T. (1992) Boswellic acids: Novel, specific, nonredox inhibitors of 5-lipoxygenase. J. Pharmacol. Exp. Ther. 261(3), 1143-1146.

6. Boswellia serrata. Alternative Medicine Review Monographs – Volume One. 2002.

7. Kulkarni RR, Patki PS, Jog VP, Gandage SG, Patwardhan B. Treatment of osteoarthritis with a herbomineral formulation: a double-blind, placebo-controlled, cross-over study. J Ethnopharmacol. 1991 May-Jun;33(1-2):91-5.

8. Majeed, M., Badmaev, V., Shivakumar, U., Rajendran, R. Curcuminoids: Antioxidant Phytonutrients. 1995. Piscataway, NJ: NutriScience Publishers.

9. Snow, J.M. Herbal Monograph: Curcuma longa L. (Zingiberaceae). The Protocol Journal of Botanical Medicine, Autumn 1995:43-46.

10. Rao, S., Rao, M.N.A. Nitric oxide scavenging by curcuminoids. J Pharm. Pharmacol. 1997;49:105-7.

11. Ramsewak, R.S., DeWitt, D.L., Nair, M.G. Cytotoxicity, antioxidant, and anti-inflammatory activities of Curcumins I-III from Curcuma longa. Phytomedicine 2000;7(4):303-308.

12. Deodhar, S.D., Sethi, R. Srimal. R.C. Preliminary study on antirheumatic activity of curcumin (diferoyl methane). Indian J Med Res 1980;71:632-34.

13. Atal, C., Zutshi, U., Rao, P. Scientific evidence on the role of Ayurvedic herbals on bioavailability of drugs. Journal of Ethnopharmacology 1981;4:229-232.

14. Bioperine®–Nature's Bioavailability Enhancing Thermonutrient. Executive Summary. 1996; Sabinsa Corporation, Piscataway, N.J.

15. Shoba, G., et al. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Medica 1998;64(4):353-6.

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for Great Joint Health buy Best Joint Support at Vitanet

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1438)

Date: August 24, 2006 03:55 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Degenerative joint disease (osteoarthritis)

Degenerative joint disease (osteoarthritis) damages or destroys cartilage and its supportive collagen structure. As many as 40 million Americans, including the majority of people over age fifty, are thought to suffer from some form of this disease. Primary osteoarthritis, the “wear and tear” form, is due to normal use and age-related causes. Secondary osteoarthritis results from repeated joint trauma, inherited predisposition, or previous inflammatory conditions. While non-steroidal anti-inflammatory drugs (NSAIDs) treat symptoms only, a natural, holistic approach strives to improve the environment of the cartilage and joint as a whole by providing protective and restorative nourishment, increased circulation, decreased inflammation and reduced free radical damage.

High levels of Glucosamine and Chondroitin Sulfate

Widely regarded as the first defense in protecting joints, glucosamine and Chondroitin sulfate have been shown to effectively control joint pain and slow down or reverse the progression of cartilage deterioration. The integrity of joint gliding surfaces as well as the health of tendons, ligaments, joint fluids, skin, bones, heart valves and virtually all structural elements in the body is dependent upon the proper synthesis and availability of proteoglycans, integral components of joint cartilage.

Glucosamine provides two components critical to the synthesis of proteoglycans: hyaluronic acid and glycosaminoglycans (GAGs).

Chondroitin sulfate represents an important group of GAGs. It is not a single compound, but rather a class of compounds with different molecular weights that each have specialized functions within the body.

Numerous studies have shown that long-term safety, reduction in pain and protection of cartilage with body chondroitin and glucosamine are comparable or superior to results obtained with NSAIDs.

MSM. (Methylsulfonylmethane) MSM is a rich source of sulfur, a mineral required for GAG synthesis. A preliminary study suggests that MSM may help reduce pain in persons with degenerative arthritis.

Gota Kola. (Centella asiatica) known to support collagen synthesis and stimulate GAG’s, Gota Kola has been used for many years in Europe to promote wound healing and blood vessel integrity. It also has been shown to improve circulation in small vessels.

Turmeric. (Curcuma longa) this saffron-colored root offers a wide range of benefits. It naturally inhibits the inflammatory COX-2 enzyme, reduces pain and is a potent antioxidant that protects the liver and other cells. High antioxidant diets may inhibit joint deterioration.

Bromelain. Derived from pineapple cores, Bromelain is most commonly used for healing soft tissue injuries and inflammation. It contains potent selective proteases (protein-digesting enzymes) and other substances which serve to block destruction of GAGs.

Trace Minerals. Micronutrients play many distinct roles in support of healthy joint connective tissue and joint cartilage matrix.

Black Pepper Extract. Bioperine is a highly concentrated extract (95% - 98% piperine) of black pepper. Used as a bioavailability enhancer, it has been shown to increase the absorption of vitamins, minerals and herbs.

--
Buy Discount Vitamins at Vitanet


Solaray Vitamins

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1356)

Date: February 10, 2006 06:38 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Goes above and beyond antioxidant protection.

Antioxidants abound in the plant kingdom. Modern science has discovered that Turmeric (Cucuma Longa) contains a family of compounds called “curcuminoids.” Known collectively as “Curcumin”, these natural plant substances are powerful antioxidants – and much more. Best Curcumin with Bioperine contains Curcumin C3 Complex, a special extract of Curcuma longa, and each capsule provides 500mg.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1209)

Date: December 07, 2005 01:37 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Allibiotic CF Fact Sheet

Allibiotic CF Fact Sheet

LIKELY USERS: People seeking support of the immune system and intestinal flora

KEY INGREDIENTS: Allicin (“AlliSure” patented, stabilized allicin from fresh garlic); Olive Leaf Extract (Olea Europaea with 18% minimum Oleuropein content); Elderberry extract, from fruit/berry, 60:1 concentrate (equivalent to 2,500 mg. of fresh berries of Sambucus nigra); Oil of Oregano (wild oregano from Origanum vulgare) ImmunEnhancer AG (trademarked Arabinogalactan from Larch Tree, Larix occidentalis)

MAIN PRODUCT FEATURES: AlliSure is the clinically tested, patented and stable form of allicin. Not allicin potential, but actual allicin. Allicin represents the immune supporting nutrients of raw garlic, and is chemically similar to penicillin, though with different physical properties. AlliSure shares garlic’s abilities to help maintain healthy cholesterol and blood pressure levels, and also has been shown to raise levels of a key T cell to enhance immune system function. Like raw garlic, AlliSure has antimicrobial properties linked to its ability to react with sulfur-containing metabolic enzymes. Allicin is also shown in studies to play a role in controlling blood sugar and abnormal cell growth.

Black Elderberries have strong antioxidant properties, containing flavonoids like anthocyanidins. They have been studied in relation to inhibition of viral replication and of minor inflammations.

Olive Leaf has been used as an antioxidant, cholesterol and blood viscosity regulator, and vasodilator. But its most important use has been as a way to help the body deal with undesirable organisms in the vital respiratory and intestinal areas.

Oil of Oregano (wild oregano, wild marjoram) contains carvacrol and thymol, which are responsible for much of its antimicrobial activities. It also has some anti-inflammatory effects.

Arabinogalactan from Larch tree bark (ImmunEnhancer AG) can help speed the immune system’s response to undesirable organisms and is often compared to Echinacea. It has also been shown to promote the growth of beneficial intestinal bacteria.

ADDITIONAL PRODUCT INFORMATION: Patented and trademarked ingredients enhance quality controls and have clinical research. Rosemary Oil provides antioxidant protection for the capsule contents. Enteric coating protects the capsule from stomach acid to deliver its contents past the stomach. This helps to assure full potency and reduces the possibility of the oils repeating.

SERVING SIZE & HOW TO TAKE IT: One softgel twice daily, preferably with meals. Try one before using the full dose.

COMPLEMENTARY PRODUCTS: Probiotics, Antioxidants, D-Flame

CAUTIONS: Pregnant & lactating women, children and people using prescription drugs should consult their physician before taking any dietary supplement. Discontinue use if any uncomfortable side effects occur. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim.

Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

REFERENCES:

ALLICIN:

Josling P. Preventing the common cold with a garlic supplement: a double-blind, placebo-controlled survey. Adv Ther. 2001 Jul-Aug;18(4):189-93. (AlliSure was used in this study.)

Abramovitz D, Gavri S, Harats D, Levkovitz H, Mirelman D, Miron T, Eilat-Adar S, Rabinkov A, Wilchek M, Eldar M, Vered Z. Allicin-induced decrease in formation of fatty streaks (atherosclerosis) in mice fed a cholesterol-rich diet. Coron Artery Dis. 1999 Oct;10(7):515-9. PMID: 10562920

Ankri S, Miron T, Rabinkov A, Wilchek M, Mirelman D. Allicin from garlic strongly inhibits cysteine proteinases and cytopathic effects of Entamoeba histolytica. Antimicrob Agents Chemother. 1997 Oct;41(10):2286-8. PMID: 9333064

Cellini L, Di Campli E, Masulli M, Di Bartolomeo S, Allocati N. Inhibition of Helicobacter pylori by garlic extract (Allium sativum). FEMS Immunol Med Microbiol. 1996 Apr;13(4):273-7. PMID: 8739190

Chowdhury AK, Ahsan M, Islam SN, Ahmed ZU. Efficacy of aqueous extract of garlic & allicin in experimental shigellosis in rabbits. Indian J Med Res. 1991 Jan;93:33-6.

Eilat S, Oestraicher Y, Rabinkov A, Ohad D, Mirelman D, Battler A, Eldar M, Vered Z. Alteration of lipid profile in hyperlipidemic rabbits by allicin, an active constituent of garlic. Coron Artery Dis. 1995 Dec;6(12):985-90. PMID: 8723021

Elkayam A, Mirelman D, Peleg E, Wilchek M, Miron T, Rabinkov A, Oron-Herman M, Rosenthal T. The effects of allicin on weight in fructose-induced hyperinsulinemic, hyperlipidemic, hypertensive rats. Am J Hypertens. 2003 Dec;16(12):1053-6. PMID: 14643581

Feldberg RS, Chang SC, Kotik AN, Nadler M, Neuwirth Z, Sundstrom DC, Thompson NH. In vitro mechanism of inhibition of bacterial cell growth by allicin. Antimicrob Agents Chemother. 1988 Dec;32(12):1763-8.

Focke M, Feld A, Lichtenthaler K. Allicin, a naturally occurring antibiotic from garlic, specifically inhibits acetyl-CoA synthetase. FEBS Lett. 1990 Feb 12;261(1):106-8.

Hirsch K, Danilenko M, Giat J, Miron T, Rabinkov A, Wilchek M, Mirelman D, Levy J, Sharoni Y. Effect of purified allicin, the major ingredient of freshly crushed garlic, on cancer cell proliferation. Nutr Cancer. 2000;38(2):245-54. PMID: 11525603

Patya M, Zahalka MA, Vanichkin A, Rabinkov A, Miron T, Mirelman D, Wilchek M, Lander HM, Novogrodsky A. Allicin stimulates lymphocytes and elicits an antitumor effect: a possible role of p21ras. Int Immunol. 2004 Feb;16(2):275-81. PMID: 14734613

Rabinkov A, Miron T, Mirelman D, Wilchek M, Glozman S, Yavin E, Weiner L. S-Allylmercaptoglutathione: the reaction product of allicin with glutathione possesses SH-modifying and antioxidant properties. Biochim Biophys Acta. 2000 Dec 11;1499(1-2):144-153. PMID: 11118647

Rabinkov A, Miron T, Konstantinovski L, Wilchek M, Mirelman D, Weiner L. The mode of action of allicin: trapping of radicals and interaction with thiol containing proteins. Biochim Biophys Acta. 1998 Feb 2;1379(2):233-44. PMID: 9528659

Sela U, Ganor S, Hecht I, Brill A, Miron T, Rabinkov A, Wilchek M, Mirelman D, Lider O, Hershkoviz R. Allicin inhibits SDF-1alpha-induced T cell interactions with fibronectin and endothelial cells by down-regulating cytoskeleton rearrangement, Pyk-2 phosphorylation and VLA-4 expression. Immunology. 2004 Apr;111(4):391-9. PMID: 15056375

Shadkchan Y, Shemesh E, Mirelman D, Miron T, Rabinkov A, Wilchek M, Osherov N. Efficacy of allicin, the reactive molecule of garlic, in inhibiting Aspergillus spp. in vitro, and in a murine model of disseminated aspergillosis. J Antimicrob Chemother. 2004 May;53(5):832-6. Epub 2004 Mar 24. PMID: 15044429

Tsai Y, Cole LL, Davis LE, Lockwood SJ, Simmons V, Wild GC. Antiviral properties of garlic: in vitro effects on influenza B, herpes simplex and coxsackie viruses. Planta Med. 1985 Oct;(5):460-1. PMID: 3001801

Uchida Y, Takahashi T, Sato N. [The characteristics of the antibacterial activity of garlic (author's transl)] Jpn J Antibiot. 1975 Aug;28(4):638-42. PMID: 1099271

Yasuo Yamada and Keizô Azuma. Evaluation of the In Vitro Antifungal Activity of Allicin. Antimicrob Agents Chemother. 1977 April; 11(4): 743–749.

ELDERBERRY:

Duke JA. CRC Handbook of Medicinal Herbs. Boca Raton, FL: CRC Press, 1985, 423.

Gruenwald J, Brendler T, Jaenicke C, et al. (eds). PDR for Herbal Medicines. Montvale, NJ: Medical Economics, 1998, 1116–7.

Mascolo N, Autore G, Capasso G, et al. Biological screening of Italian medicinal plants for anti-inflammatory activity. Phytother Res 1987;1:28–31.

Murkovic M, Abuja PM, Bergmann AR, et al. Effects of elderberry juice on fasting and postprandial serum lipids and low-density lipoprotein oxidation in healthy volunteers: a randomized, double-blind, placebo-controlled study. Eur J Clin Nutr. Feb2004;58(2):244-9.

Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-Care Professionals. London: The Pharmaceutical Press, 1996, 104–5.

Yesilada E. Inhibitory Effects of Turkish Folk Remedies on Inflammatory Cytokines: Interleukin-1Alpha, Interleukin-1Beta and Tumor Necrosis Factor Alpha. J Ethnopharmacol. Sept1997;58(1):59-73. Youdim KA, Martin A, Joseph JA. Incorporation of the elderberry anthocyanins by endothelial cells increases protection against oxidative stress. Free Radical Biol Med 2000;29:51–60.

Zakay-Rones Z, Varsano N, Zlotnik M, et al. Inhibition of several strains of influenza virus in vitro and reduction of symptoms by an elderberry extract (Sambucus nigra L.) during an outbreak of influenza B Panama. J Alt Compl Med 1995;1:361–9.

OLIVE LEAF EXTRACT:

American Herbal Products Association. Use of Marker Compounds in Manufacturing and Labeling Botanically Derived Dietary Supplements. Silver Spring, MD: American Herbal Products Association; 2001.

Bennani-Kabchi N, et al. Effects of Olea europea var. oleaster leaves in hypercholesterolemic insulin-resistant sand rats. Therapie. Nov1999;54(6):717-23.

Bisignano G, et al. On the in-vitro antimicrobial activity of oleuropein and hydroxytyrosol. J Pharm Pharmacol. Aug1999;51(8):971-4. Gonzalez M, et al. Hypoglycemic activity of olive leaf. Planta Medica. 1992;58:513-515. Visoli F, et al. Oleuropein protects low density lipoprotein from oxidation. Life Sciences. 1994;55:1965-71. PDR for Herbal Medicines, 2nd edition. Montvale, NJ: Medical Economics Company; 2000:557.

Petroni A, et al. Inhibition of platelet aggregation and eicosanoid production by phenolic components of olive oil.Thromb Res. Apr1995;78(2):151-60. Pieroni A, et al. In vitro anti-complementary activity of flavonoids from olive (Olea europaea L.) leaves. Pharmazie. Oct1996;51(10):765-8. Zarzuelo A, et al. Vasodilator effect of olive leaf. Planta Med. Oct1991;57(5):417-9. OREGANO OIL (OIL OF OREGANO, WILD OREGANO, WILD MARJORAM):

Dorman HJ, et al. Antimicrobial agents from plants: antibacterial activity of plant volatile oils. J Appl Microbiol. Feb2000;88(2):308-16. Force M, et al. Inhibition of enteric parasites by emulsified oil of oregano in vivo. Phytother Res. May2000;14(3):213-4.

Hammer KA, Carson CF, Riley TV. Antimicrobial activity of essential oils and other plant extracts. J Appl Microbiol 1999;86:985–90.

Kelm MA, Nair MG, Strasburg GM. Antioxidant and Cyclooxygenase Inhibitory Phenolic Compounds from Ocimum sanctum Linn. Phytomedicine. Mar2000;7(1):7-13. Lamaison JL, et al. Medicinal Lamiaceae with antioxidant properties, a potential source of rosmarinic acid. Pharm Acta Helv. 1991;66(7):185-8.

Ponce MM, Navarro AI, Martinez GMN, et al. In vitro effect against Giardia of 14 plant extracts. Rev Invest Clin 1994;46:343–7 [in Spanish].

Stiles JC, Sparks W, Ronzio RA. The inhibition of Candida albicans by oregano. J Applied Nutr 1995;47:96–102.

Tantaoui EA, Beraoud L. Inhibition of growth and aflatoxin production in Aspergillus parasiticus by essential oils of selected plant materials. J Environ Pathol Toxicol Oncol 1994;13:67–72. ImmunEnhancer AG (Larch tree Arabinogalactan)

Corado J, et al. Impairment of Natural Killer (NK) Cytotoxic Activity in Hepatitis C Virus (HCV) Infection. Exp Immunol. 1997;109:451-457. Currier NL, Lejtenyi D, Miller SC. Effect over time of in-vivo administration of the polysaccharide arabinogalactan on immune and hemopoietic cell lineages in murine spleen and bone marrow. Phytomedicine. 2003 Mar;10(2-3):145-53. PMID: 12725568

Egert D, et al. Studies on Antigen Specificity of Immunoreactive Arabinogalactan Proteins Extracted from Baptisia tinctoria and Echinacea purpurea. Planta Med. 1992;58:163-165. Gonda R, et al. Arabinogalactan Core Structure and Immunological Activities of Ukonan C, An Acidic Polysaccharide from the Rhizome of Curcuma longa. Biol Pharm Bull. 1993;16:235-238. Hagmar B, et al. Arabinogalactan Blockade of Experimental Metastases to Liver by Murine Hepatoma. Invasion Metastasis. 1991;11:348-355. Kelly GS. Larch arabinogalactan: clinical relevance of a novel immune-enhancing polysaccharide. Altern Med Rev. 1999 Apr;4(2):96-103. Review. PMID: 10231609

Kim LS, Waters RF, Burkholder PM. Immunological activity of larch arabinogalactan and Echinacea: a preliminary, randomized, double-blind, placebo-controlled trial. Altern Med Rev. 2002 Apr;7(2):138-49. PMID: 11991793

Levine PH, et al. Dysfunction of Natural Killer Activity in a Family With Chronic Fatigue Syndrome. Clin Immunol Immunopathol. 1998;88:96-104. Robinson RR, Feirtag J, Slavin JL. Effects of dietary arabinogalactan on gastrointestinal and blood parameters in healthy human subjects. J Am Coll Nutr. 2001 Aug;20(4):279-85. PMID: 11506055

Rolfe RD. The Role of Probiotic Cultures in the Control of Gastrointestinal Health. J Nutr. Feb2000;130(2S Suppl):396S-402S.

Salyers AA, Vercellotti JR, West SE, Wilkins TD. Fermentation of mucin and plant polysaccharides by strains of Bacteroides from the human colon. Appl Environ Microbiol. 1977 Feb;33(2):319-22. PMID: 848954

Uchida A. Therapy of Chronic Fatigue Syndrome. Nippon Rinsho. 1992;50:2679-2683.

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Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=987)

Date: August 19, 2005 12:47 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Curcumin - Turmeric Extract

Curcumin

Turmeric- History and Traditional Usage

Native to Southeast Asia, Curcuma longa is a tall
tropical shrub with large oblong leaves and pale yellow flowers.
The genus “Curcuma” belongs to the Zingiberaceae family, which
includes ginger.1 The plant possesses a large root structure
with fleshy, bulbous underground parts called “rhizomes.” These
rhizomes, known as turmeric root, are harvested at maturity,
dried and cured for commercial use. Chemical analysis shows that
dried turmeric contains essential and volatile oils, with a
curcuminoid content of 2.5 to 5.0 %.2

In addition to its
popularity as a spice, turmeric is used as a dye for cloth and
coloring agent in foods and cosmetics, thanks to its rich yellow
color. Turmeric also serves as a preservative, probably owing to
the antioxidant and antimicrobial properties of curcumin.
Extracts of Curcuma longa have demonstrated in vitro
antibacterial and anti-fungal effects.3

Turmeric is named in
ancient Ayurvedic and Chinese herbal texts as a traditional folk
remedy. Historically, turmeric was used externally for wounds,
and sprains, and internally for digestive complaints,
rheumatism, liver disorders, coughs and colds.4
Benefits

Protects cells and tissues by fighting free radicals.*

Supports joint function*

The numerous beneficial
effects attributed to turmeric stem in large measure from the
antioxidant properties of curcumin. Antioxidants neutralize free
radicals, which are highly unstable molecules that can damage
cellular structures through abnormal oxidative reactions.
Curcumin is a potent “scavenger” of the superoxide radical, a
free radical that initiates potentially harmful oxidative
processes such as lipid peroxidation.5 Through this activity,
curcumin has been shown to protect skin cells from the injurious
effect of nitroblue tetrazolium, a toxin that generates
superoxide radicals. Curcumin also increases survival of cells
exposed in vitro to the enzyme hypoxanthine/xanthine oxidase,
which stimulates superoxide and hydrogen peroxide production.
Curcumin itself is not toxic to cells, even at high
concentrations. Pure curcumin was shown to be less protective
than a mixture of curcuminoids, indicating a possible synergism
among curcuminoids.6 Because free radicals are involved in aging
and exert harmful effects on skin, these results suggest
curcumin may help slow skin aging.

Curcumin demonstrates
several other in vitro effects linked to free radical
scavenging. Curcumin scavenges nitric oxide, a compound
associated with the body’s inflammatory response.7 Pure curcumin
and turmeric extracts protect red blood cells from lipid
peroxidation induced by hydrogen peroxide.8 Curcumin has been
shown to protect DNA from oxidative damage, inhibit binding of
toxic metabolites to DNA, and reduce DNA mutations in the Ames’
test.9 Although additional studies suggest an anticarcinogenic
effect of curcumin, through protection of DNA,10 one in vitro
study found that curcumin induced DNA damage in human gastric
mucosal cells.11 It is speculated that curcumin may act as a
pro-oxidant in the presence of transition metal ions such as
copper and iron. (This is true for other antioxidants, including
vitamin C.) Curcumin also demonstrates in vitro inhibition of
COX-I and COX-II enzymes, which are involved in the inflammatory
reaction.12 Together these results strongly suggest that
curcumin is a potent bioprotectant with a potentially wide range
of therapeutic applications.

Animal studies- In vivo protective effects

Through its free radical scavenging
properties, curcumin has shown bioprotective effects in animals.
In one study, rats were treated with isoproterenol, a chemical
that causes cardiac hypertrophy (enlargement of the heart) due
to abnormal collagen metabolism. Co-treatment with curcumin
reversed the degradation of collagen and cardiac hypertrophy
induced by isoproterenol.13 Curcumin protects mice from
detrimental effects of radiation, by stabilizing the glyoxalase
system, a biological system that regulates cell division.14
Curcumin protects livers of rats from the damaging effects of
carbon tetrachloride (CCl4), a potent hepatoxin that injures the
liver via its free radical metabolite, CCl3.15,16 Curcumin
protected rats from alcohol-induced brain damage, in a study in
which oral administration of curcumin reversed lipid
peroxidation, reduced levels of free-radical metabolites and
increased levels of glutathione, a major physiologic
antioxidant.17 Curcuma longa extracts have shown
anti-inflammatory effects in rats.18

Human Trials

Curcumin exhibits free-radical scavenging ability when
administered to humans. In an open trial (uncontrolled), 18
healthy individuals ranging in age from 27 to 67 years consumed
a Curcuma longa extract, at a dose supplying 20 mg curcuminoids,
for 45 days. Before and after blood tests showed a statistically
significant decrease in lipid peroxides.19 Preliminary trials
have tested the anti-inflammatory action of curcumin, with
results that verify the traditional use of turmeric as an
anti-rheumatic herb. In a short-term double-blind, cross-over,
comparative study, 18 people received curcumin (1200 mg daily)
or phenylbutazone for two week periods. Both curcumin and
phenylbutazone produced measurable improvements in joint
flexibility and walking time. The subjects reported results only
with phenylbutazone, which may be explained by the short
duration of the trial.20 In a small placebo-controlled trial
comparing curcumin to phenylbutazone, 45 patients with
post-operative inflammation received curcumin, phenylbutazone or
placebo. The anti-inflammatory effects of curcumin and
phenylbutazone were comparable and superior to placebo.21
Curcumin has not been found to produce an analgesic (pain
relieving) effect.

Bioperine-Nature’s Absorption Enhancer
Boosts Curcumin Absorption*

Traditional Ayurvedic herbal
formulas often include black pepper and long pepper as
synergistic herbs. The active ingredient in both black pepper
and long pepper is the alkaloid, piperine. Experiments carried
out to evaluate the scientific basis for the use of peppers have
shown that piperine significantly enhances bioavailability when
consumed with other substances.22 Several double-blind clinical
studies have confirmed that Bioperine® increases absorption of
nutrients.23

Curcumin is poorly absorbed in the intestinal
tract, limiting its therapeutic effectiveness. Oral doses are
largely excreted in feces, and only trace amounts appear in the
blood. Concomitant administration of 20 mg of piperine with 2
grams of curcumin increases the bioavailability of curcumin by
2000%.24

Scientific References

1. Majeed, M., Badmaev,
V., Shivakumar, U., Rajendran, R. Curcuminoids. 1995.
Piscataway, NJ: NutriScience Publishers.
2. Srimal, R.C.
Turmeric: a brief review of its medicinal properties.
Fitoterapia 1997;68(6):483-93.
3. Ammon, H.P.T., Wahl, M.A.
Pharmacology of Curcuma longa. Planta Medica 1991;57:1-7.
4.
Snow, J.M. Herbal Monograph: Curcuma longa L. (Zingiberaceae).
The Protocol Journal of Botanical Medicine, Autumn
1995:43-46.
5. Rao, N.S., Rao, M.N.A. Free radical scavenging
activity of curcuminoids. Arzneim.-Forsch./Drug Res.
1996;46(2):169-171.
6. Bonté. F. et al. Protective effect of
curcuminoids on epidermal skin cells under free oxygen radical
stress. Planta Medica 1997;63:265-66.
7. Rao, S., Rao, M.N.A.
Nitric oxide scavenging by curcuminoids. J Pharm. Pharmacol.
1997;49:105-7.
8. Lalitha, S., Selvam, R. Prevention of
H2Os-induced red blood cell lipid peroxidation by aqueous
extracted turmeric. Asia Pacific J Clin Nutr
1999;8(2):113-14.
9. Deshpande, S.S., Maru, G.B. Effects of
curcumin on the formation of benzo[a]pyrene derived DNA adducts
in vitro. Cancer Letters 1995;96:71-80.
10. Subramanian, M., et
al. Diminution of singlet oxygen-induced DNA damage by curcumin
and related antioxidants. Mutation Research
1994;311:249-55.
11. Blasiak, J., Trzeciak, A., Kowalik, J.
Curcumin damages DNA in human gastric mucosa cells and
lymphocytes. Journal of Environmental Pathology, Toxicology and
Oncology 1999;18(4):271-76.
12. Ramsewak, R.S., DeWitt, D.L.,
Nair, M.G. Cytotoxicity, antioxidant, and anti-inflammatory
activities of Curcumins I-III from Curcuma longa. Phytomedicine
2000;7(4):303-308.
13. Nirmala, C. Anand, S., Puvanakrishnan,
R. Curcumin treatment modulates collagen metabolism in
isoproterenol induced myocardial necrosis in rats. Molecular and
Cellular Biochemistry 1999;197:31-37.
14. Choudhary, D.,
Chandra, D. Kale, R.K. Modulation of radioresponse of glyoxalase
system by curcumin. Journal of Ethnopharmacology
1999;64:1-7.
15. Park, E-J. et al. Protective effect of
curcumin in rat liver injury induced by carbon tetrachloride. J
Pharm. Pharmacol. 2000;52:437-40.
16. Deshpande, U.R. et al.
Protective effect of turmeric (Curcuma longa L.) extract on
carbon tetrachloride-induced liver damage in rats. Indian
Journal of Experimental Biology 1998;36:573-77.
17.
Rajakrishnan, V. et al. Neuroprotective role of curcumin from
Curcuma longa on ethanol-induced brain damage. Phytotherapy
Research 1999;13:571-74.
18. Arora, R.B. Basu, N., Kapoor, V.,
Jain, A.P. Anti-inflammatory studies on Curcuma longa
(Turmeric). Indian J Med Res 1971;59(8):1289-95.
19.
Ramirez-Bosca, A. et al. Antioxidant Curcuma extracts decrease
the blood peroxide levels of human subjects. Age
1995;18:167-69.
20. Deodhar, S.D., Sethi, R. Srimal. R.C.
Preliminary study on antirheumatic activity of curcumin
(diferoyl methane). Indian J Med Res 1980;71:632-34.
21.
Satoskar, R.R., Shah, S J. Shenoy, S.G. Evaluation of
anti-inflammatory property of curcumin (diferoyl methane) in
patients with postoperative inflammation. International Journal
of Clinical Pharmacology, Therapy and Toxicolgy
1986;24(12):651-54.
22. Atal, C., Zutshi, U., Rao, P.
Scientific evidence on the role of Ayurvedic herbals on
bioavailability of drugs. Journal of Ethnopharmacology
1981;4:229-232.
23. Bioperine®–Nature's Bioavailability
Enhancing Thermonutrient. Executive Summary. 1996; Sabinsa
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24. Shoba, G., et al. Influence
of piperine on the pharmacokinetics of curcumin in animals and
human volunteers. Planta Medica 1998;64(4):353-6.

© 2002
Doctor's Best, Inc. Revised 8/13/02

*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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Vitanet ®

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Date: June 11, 2005 05:18 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The Flex Factor

The Flex Factor by Thomas Dunville Energy Times, February 10, 2004

Arthritis, according to recent research, presents its sufferers with a Catch-22: The nagging pain of this condition can send your spirits plummeting. But, then, the depression spurred by the disconsolate persistence of arthritic pain can make the condition worse.

Part of the trick is not to give in. If you can keep a bright mood even as your joints start to ache, the pain may lessen.

While nobody can offer a guaranteed, 100% effective cure for arthritis, you don't have to be a passive victim. Exercise, the proper nutrients and a positive, can-do attitude can ease arthritis pain so effectively that scientists have been able to measure the difference. While medical researchers recognize the existence of over 100 types of arthritis, most people with achy joints suffer from osteoarthritis, which is caused by everyday wear and is found in just about everyone over age 60. When this condition occurs, the body's cushioning, its cartilage, thins and the inner surfaces of joints grind together painfully.

Although aging itself increases your chances of enduring achy joints, other factors can also put you in the way of osteoarthritis. If you carry too much weight, it can wear on your joints. In addition, suffering a joint injury when you're young can increase your risk of developing osteoarthritis as you age.

In another prevalent form of joint pain, rheumatoid arthritis (RA), the body's immune system mistakenly attacks the membranes lining the joints, causing swelling and pain. About 2 million Americans suffer from RA, which affects women about twice as often as men.

Exercise Away Arthritic Woes

Weekend warriors, don't despair! Arthritis doesn't have to mean the end of your weekend athletic wars. Matter of fact, in many cases, experts now recommend exercise to reduce the effects of arthritis.

While that might sound counterintuitive, a study out of the Netherlands shows that folks in the early stages of rheumatoid arthritis who work out twice a week for about an hour each session may enjoy better physical and mental health than couch potatoes who receive physical therapy.

The Dutch study took 150 people, many of whom had just started to suffer from rheumatism, and enrolled them in RAPIT, an acronym for Rheumatoid Arthritis Patients in Training. Rather than letting these folks rest their inflamed joints, twice a week the research team took them to the gym where they did:

• Cooling down with stretches: 15 minutes

When the researchers compared the physical changes in these arthritis sufferers with 150 others with similar arthritis complaints who underwent physical therapy without organized physical activity, they found that after two years the exercisers had benefited greatly. They were stronger and more aerobically fit, could perform everyday tasks more effectively and possessed a better, more optimistic mental attitude (Arthritis and Rheumatism 2003; 48(9):2415-24).

However, the exercisers who were already suffering severe rheumatoid arthritis did experience some extra joint damage, so the researchers believe this kind of program is better for those in the early stages of the disease. " This study demonstrates that participation in long-term high-intensity exercise classes decreases the level of psychological distress in RA patients," says researcher Zuzana de Jong, MD, a professor at the Leiden University Medical Center in the Netherlands.

Fish Oil Lowers Arthritis Risk

Fish oil-in particular, cod liver oil-may be able to help ease osteoarthritis.

In looking at the effects of fish oil, researchers at Cardiff, Wales, discovered indications that "...the omega-3 fatty acids in cod liver oil can reduce cartilage degradation and inflammation in arthritic disease," according to Bruce Caterson, PhD, one of the scientists involved.

Dr. Caterson adds, "Our most recent work shows that by exposing human osteoarthritic cartilage to cod liver oil in the laboratory for just 24 hours we can turn off, or reverse, the action of the degradative enzymes and inflammatory factors affecting the tissue." John Harwood, PhD, another member of the Cardiff research team, adds, "This is where science and old wives' tales coincide. Our findings are consistent with advice that taking cod liver oil in early adulthood could prevent the onset of osteoarthritis and would reduce the harmful symptoms associated with the disease."

Dr. Caterson further explains that the omega-3 fatty acids in cod liver oil inhibit enzymes that break down aggrecan and collagen, substances that cushion joints. Consequently, cartilage stays healthier, inflammation is lessened and arthritic pain decreases. The anti-inflammatory action of omega-3s in fighting rheumatoid arthritis is also supported by studies performed in the US (Am J Clin Nutr 2000; 71(1 Suppl):349S-51S).

Other research shows that if you take natural vitamin E along with fish oil, you may improve even further your odds of relieving arthritis or lessening its effects (JACN 10/30/00).

Glucosamine Repair

Glucosamine, the stuff that cartilage is made from, has been shown to lower the risk of arthritis and possibly relieve its pain. This natural substance, made from a sugar and a molecule called an amine, is a building block of joint tissue. As a result, experts believe, when you take it in supplemental form, the body may use it to repair joints that have been damaged by arthritis. For instance, an investigation of osteoarthritis of the knee performed at the University of Liege in Belgium showed that taking glucosamine could stop joints from deteriorating.

The study, which involved more than 200 people suffering from osteoarthritis, found that in three years of taking glucosamine supplements, many arthritis sufferers found that their condition actually improved (Lancet 2001 Jan 27; 357).

Other Arthritis Fighters

Chondroitin sulfate is another material that goes into the making of cartilage. Chondroitin helps cartilage stay hydrated and permits the flow of nutrients through the joint tissues. In addition, researchers believe that chondroitin helps fight inflammation, which can otherwise cause pain and stiffness as well as joint destruction.

Taken together with glucosamine, chondroitin is believed to hasten the healing of bone and cartilage. Another substance that may help ease the ache of arthritis is methylsulfonylmethane (MSM), a naturally occurring sulfur-bearing compound. "MSM appears to have anti-inflammatory effects when administered orally, intravenously or topically," says MSM researcher Stanley Jacob, MD, FACS, of the Oregon Health & Science University. That means it has shown an ability to reduce the heat, pain and swelling associated with arthritic conditions. MSM may also be able to reduce muscle spasms around joints and reduce the formation of scar tissue.

Herbal Aid

Herbal medicine has long been used by folks with achy joints. The yellow spice turmeric (Curcuma longa), a staple of Indian cooking, is a traditional Indian remedy for arthritis because of its painkilling properties. Ginger (Zingiber officinale), another culinary favorite, restrains the production of inflammatory chemicals called cytokines. And willow bark (Salix sp), the source of aspirin, is longer-acting and doesn't irritate the stomach lining.

Those who suffer arthritis know that its pain and discomfort are often no laughing matter. But if you don't take arthritis lying down and manage to keep a smile on your face-and avail yourself of nature's remedies-you can get the upper hand on this often debilitating condition.

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Vitanet ®

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MYELIN SHEATH SUPPORT™ - Herbal-Nutrient Nervous System Support!

Date: June 04, 2005 10:15 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: MYELIN SHEATH SUPPORT™ - Herbal-Nutrient Nervous System Support!

Myelin Sheath Support

Planetary Formulas is pleased to introduce MYELIN SHEATH SUPPORT: a comprehensive formula designed to support the fat-like insulating sheath (myelin) that surrounds nerve tissues. Properly formed myelin is necessary for optimal nerve conduction. MYELIN SHEATH SUPPORT is the first formula developed for Planetary Formulas by herbalist and Ayurvedic specialist Alan Tillotson. It consists of some of the most highly regarded tonifiers of Chinese and Ayurvedic herbalism, along with additional key botanicals and supporting nutrients used with success in his practice.

Nervous System Support

MYELIN SHEATH SUPPORT is a broad-range herbal-nutrient formula that supports your nervous system with traditional Ayurvedic and Chinese botanicals as well as scientifically researched nutrients. Vitamin B-12 is key to the MYELIN SHEATH SUPPORT formula. It plays two critical roles: 1) it is essential for normal health of blood; and 2) it may function as a coenzyme in the synthesis of either the protein or lipid part of myelin.

Comprehensive Botanical - Nutrient Formula

Ayurvedic botanicals: Ashwagandha has been widely used throughout India for 3,000-4,000 years. It is one of the most highly regarded tonics in the 6,000-year old Ayurvedic tradition. Bacopa has been reported by Ayurvedic scholar Charaka to promote mental ability. Yogaraj guggul is one of the most valued botanical compounds of Ayurveda. The boswellic acids in boswellia inhibit leukotriene synthesis. Shilajit, a mineral resin that oozes from steep rocks in the Himalayas, is used extensively in Ayurveda. Curcuma (turmeric) has been used both internally and externally in Ayurveda. Curcuma is included in a dosage clinically shown to inhibit a group of enzymes that influence metabolism of arachidonic acid. Arachidonic acid is an unsaturated fatty acid found in most animal fats and is a precursor of prostaglandins. Chinese herbs: Included are the Chinese tonifiers panax ginseng and tienchi ginseng, as well as licorice extract (which is also prominent in European herbalism). MYELIN SHEATH SUPPORT delivers panax ginseng in amounts clinically shown to have adaptogenic (anti-stress) effects. Nutrients: Vitamin B-12, central for supporting the nervous system and specifically the myelin sheath, is included in the form of methylcobalamin. While a few forms of B-12 have been used clinically, it has been shown that methylcobalamin is a highly assimilable form of B-12, leading to increased retention in tissues. MYELIN SHEATH SUPPORT also includes zinc, copper, L-selenomethionine, boron, calcium, potassium, magnesium, chromium and pantothenic acid.

New Formulator!

Alan Tillotson is the newest member of the Planetary Formulas formulation team. He has been an ardent student of Ayurvedic herbalism, having engaged in an apprenticeship since 1976 with Ayurvedic scholar Mana Bajra Bajracharya, a practitioner whose family’s Ayurvedic lineage dates back 700 years. Planetary Formulas MYELIN SHEATH SUPPORT is available in bottles of 45, 90 and 180 tablets. Planetary Formulas: More than Herbs— Herbalism!

References
Ammon, H.P.T. et al. 1993. Mechanism of antiinflammatory actions of curcumin and boswellic acids. J. Ethnopharmacology: 38:113. Bhattacharya, S.K. 1995. Activity of shilajit on alloxan-induced hyperglycaemia in rats. Fitoterapia LXVI, 4:328-332. Linder, M.C. 1991. Nutritional Biochemistry and Metabolism with Clinical Applications. 2nd ed. Norwalk: Appleton and Lange, 138-143.

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VitaNet ®
VitaNet ® Staff

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