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Reduce your risk of cirrhosis and liver cancer, researchersdiscover an effective natural solution Darrell Miller 4/30/19
Prevent the number one cause of premature death by simply takingvitamin C Darrell Miller 11/16/18
Gut microbes can fight parasites: Probiotics may reduce infections, and severity of infections, in developing countries Darrell Miller 6/8/18
Get Rid of Eye-Bags and Dark Circles Naturally Darrell Miller 1/10/18
The Toenail Fungus On My Feet Destroyed My Life Until I Found How To Destroy Them!! Darrell Miller 6/16/17
How to treat and heal a sunburn Darrell Miller 6/11/17
What causes cancer? The five vectors of chemical assault on your health Darrell Miller 12/3/16
Look Younger With This Natural Facial Exfoliator Darrell Miller 11/11/15
What Is GMO and Why Should We Avoid It? Darrell Miller 6/21/14
Can Butcher's Broom Boost Cardiovascular Health? Darrell Miller 10/30/13
How D-ribose boost energy levels in the body Darrell Miller 10/27/13
Can Butcher's Broom Help Fight Varicose Veins? Darrell Miller 1/11/13
What Herbs Are Vein Strengtheners? Darrell Miller 9/28/11
Why Is The Amino Acid Tyrosine So Good for the Brain? Darrell Miller 6/18/11
Butcher's Broom Extract Darrell Miller 5/2/08
Ubiquinol Reduced CoQ10 Darrell Miller 4/7/08
Boost Beauty with Vitamin Supplements Darrell Miller 11/15/07
Ubiquinol Darrell Miller 10/24/07
The Awesome Foursome: Coenzyme Q10, D-Ribose, L-Carnitine, and Magnesium Darrell Miller 5/18/07
Vitamin D May Show Benefits Against Breast and Colorectal Cancer Darrell Miller 2/27/07
Med schools failing on nutrition teaching Darrell Miller 9/19/06
Sytrinol 150mg - Now Vitamins Darrell Miller 8/29/06
Americans, on the whole, are fatter than just about any other group... Darrell Miller 3/18/06
Dr. Verghese, M.D. Liver Detoxifier & Regenerator Fact Sheet Darrell Miller 12/7/05
Maintaining Healthy Veins Darrell Miller 7/25/05
Nothing to Sneeze At Darrell Miller 6/18/05
Inflama Rest - Natural COX-2 Inhibitor for Joint Comfort Darrell Miller 6/2/05
HEART RESPONSE - Comprehensive Support for a Healthy Heart! Darrell Miller 6/2/05
Garlic Consumption and Cancer Prevention... Darrell Miller 5/12/05
Garlic as a Lipid Lowering Agent-A Meta-Analysis Darrell Miller 5/12/05



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Reduce your risk of cirrhosis and liver cancer, researchersdiscover an effective natural solution
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Date: April 30, 2019 03:57 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Reduce your risk of cirrhosis and liver cancer, researchersdiscover an effective natural solution





Cirrhosis and liver cancer are common diseases that can be easily prevented. There are many ways to reduce the chance of developing these diseases over the course of a lifetime, such as moderate physical activity. Resistance training in particular can help to alleviate symptoms and reduce the likelihood of developing these diseases because it can lower fat levels. Exercise can also lower cholesterol and help manage weight. To sum, healthy lifestyle choices and changes can reduce the risk of cancer associated with the liver and cirrhosis, which will ultimately lead to a positive and healthy life.

Key Takeaways:

  • Nonalcoholic fatty liver disease is estimated to affect about thirty percent of Americans which translates to about a hundred million Americans.
  • Recent research from the University of Liverpool, UK, has shown that physical exercise, particularly resistance training, can reduce the risk of having liver cancer.
  • The liver is an important organ in the body that is involved in a lot of detoxification and it was shown that exercising was more beneficial for obese people.

"At the end of the study period, both liver fat and cholesterol levels were significantly lower."

Read more: https://www.naturalhealth365.com/fatty-liver-disease-solutions-2916.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6222)


Prevent the number one cause of premature death by simply takingvitamin C
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Date: November 16, 2018 09:51 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Prevent the number one cause of premature death by simply takingvitamin C





According to the data, it's been estimated that as many as half of all premature deaths are preventable, moreover that poor nutritional intake is at the core of the problem. One such nutritional deficit that could lower the number of premature deaths is the deficit of vitamin C. Vitamin C is a well-known immune system booster. However, it also has an important role to fulfill when it comes to cardiovascular health. The journal of the American College of Nutrition recently attests to this fact. The journal reported findings that agreed that the use of vitamin C reduced the incidence of cardiac disease. The findings were based on a study of over 100 men, many of whom were smokers. Those given the highest dosage of vitamin C slashed their risk for cardiac complications by more than half. Danish research further augments this aspect of vitamin C. Data pools acquired from 100,000+ Danes showed high vitamin C concentrations among those who regularly consumed a large array of fruits and vegetables. This higher level was auspiciously linked with a lowered risk of cardiovascular disease and premature death.

Key Takeaways:

  • Long accumulated data strongly suggests that up to half of all early deaths are preventable.
  • Vitamin C has a profound effect on coronary heart disease, and it has protective ability even when the vitamin C user is a smoker.
  • One recent study which supports this contention used 108 different male subjects, many of whom smoked.

"The reality is that an inexpensive vitamin supplement could reduce the rate of coronary heart disease but mainstream medicine is so deeply entrenched in pharmaceutical dogma, the idea that nutrients can prevent disease is downright blasphemous."

Read more: https://www.naturalnews.com/2018-11-12-prevent-number-one-cause-of-premature-death-vitamin-c.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5836)


Gut microbes can fight parasites: Probiotics may reduce infections, and severity of infections, in developing countries
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Date: June 08, 2018 09:16 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Gut microbes can fight parasites: Probiotics may reduce infections, and severity of infections, in developing countries





Gut microbes can fight parasites: Probiotics may reduce infections, and severity of infections, in developing countries

Parasites are a more common problem in some parts of the world, where soil quality is particularly conducive to their survival and growth. Unfortunately, for individuals that get infected with these parasites, it's becoming harder to get rid of them, as successive strains become more resistant to drugs.

Fortunately, new research is discovering that keeping parasites at bay and destroying those already present may have more to do with the environment of the gut. Individuals from villages in Indonesia and Liberia were the data pool used to find guts harboring parasites as well as those free of them. It was found that some bacteria were actually assistive of the parasites, while others made it hard on them. Since inflammation is the way that the gut generally fights off parasitic invasion, those bacteria that are anti-inflammatory are not useful in ridding the body, although those that aid in producing an inhospitable environment are. It may be that a eating a great deal more fermented foods could be a key, as such foods encourage the production of friendly and useful bacteria.

Key Takeaways:

  • Researchers used a data pool culled from fecal samples of Liberian and Indonesian villagers to try and discover what sort of gut environment is hospitable or hostile to parasitic invaders.
  • Despite the distance between the village sources, the gut environments were very similar and scientists were able to isolate many microbes.
  • The lower incidence of parasites in some individuals was deemed as possibly related to inflammation, which is the body's way of ousting parasites.

"Your ability to fight off parasitic worms may be aided by your gut microbiota."

Read more: https://www.naturalnews.com/2018-06-05-gut-microbes-can-fight-parasites-probiotics-may-reduce-infections-and-severity-of-infections-in-developing-countries.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5630)


Get Rid of Eye-Bags and Dark Circles Naturally
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Date: January 10, 2018 03:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Get Rid of Eye-Bags and Dark Circles Naturally





Eye bags can be a worrying thing. While not necessarily a health risk, the can show that you are not sleeping enough. They are almost like bruises, with blood pooling under the skin and showing those dark circles. You can help these problems with a few easy tricks. The first involve being more healthy, by cutting back on smoking and alcohol. You can also place potatoes or cucumbers on those areas, acting almost like a ice pack, to help bring down any swelling.

Key Takeaways:

  • there are a number of causes for dark eye circles including genetic, environmental factors and the very thin skin under our eyes
  • all eye dark circles are not created equal, there is hyperpigmentation of the skin and other causes
  • here's what you can do to help: no smoking, less alcohol, a clean face at night, wear your sunglasses outside

"Although under eye dark circles are not exactly a health hazard but they may impact one’s look and hence confidence negatively."

Read more: http://www.business-standard.com/article/health/get-rid-of-eye-bags-and-dark-circles-naturally-118010800598_1.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5488)


The Toenail Fungus On My Feet Destroyed My Life Until I Found How To Destroy Them!!
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Date: June 16, 2017 05:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: The Toenail Fungus On My Feet Destroyed My Life Until I Found How To Destroy Them!!





Toenail fungus can be a problematic issue, caused by poor hygiene, excessive moisture from sweating, and going bare footed in public baths and Pools. It's important to keep your feet dry, but moisturized enough that cracks don't develop in the skin.This is especially important during the summer months. One remedy for those affected by foot fungus is to soak the feel in a mixture of apple cider vinegar and water. 1 cup of vinegar and two cups of water for about 15 to 20 minutes. Dry the feet thoroughly, and repeat, but add 5 table spoons of baking soda to the mix, soak the feet again for 15 to 20 minutes.Doing this regularly will help destroy the fungus and improve foot health.

https://www.youtube.com/watch?v=cpFXG8nQYEk&rel=0

Key Takeaways:

  • Apple vinegar can be used to fight against foot fungus infection
  • it's even more efficient in killing foot fungus by combining apple vinegar with baking soda
  • this natural remedy is able to slowly, but permanently eliminate the fungus.

"Nail fungus is a recurring problem, when people do not have the necessary hygiene, or when they attend public baths, or swimming Pools."

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4840)


How to treat and heal a sunburn
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Date: June 11, 2017 09:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: How to treat and heal a sunburn





Summer is here which means people will be getting sunburned if they're not creful. Sun screen helps avoid this but it isn't fool proof. If you do get sunburned this gives you good advice on how to heal it. It can be very painful depending on how bad it is so this will help you a lot. You'll want relief and fast healing because it can hurt to even have a shirt on if it's too bad.

Key Takeaways:

  • First step in treating a sun burn is to determine how bad it is. There are four degrees to a burn, each will require a different set of treatment options.
  • Second step in treating a sun burn is reducing your agony. It is recommended to take Anti-Inflammatory pain killers. Use a hypoallergenic ointment and aloe vera. Finally drink lots of water.
  • Do not use ointments containing neomycin, bacitracin, or lanolin because they are ineffective or can cause an allergic reaction.

"And yes: We all inevitably get burned, whether we fall asleep in the hammock or forget to reapply sunscreen after a dip in the pool. So while you heal from your latest burn (or in preparation for your next one…), we suggest you stock up on tough sunscreens and SPF-packed moisturizers."

Read more: http://www.mensfitness.com/styleandgrooming/how-treat-and-heal-sunburn

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4809)


What causes cancer? The five vectors of chemical assault on your health
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Date: December 03, 2016 06:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: What causes cancer? The five vectors of chemical assault on your health





Cancer is a complex group of diseases with many possible causes. In this section you can learn more about the known causes of cancer, including genetic factors; lifestyle factors such as tobacco use, diet, and physical activity; certain types of infections; and environmental exposures to different types of chemicals and radiation.

Key Takeaways:

  • If you accidentally eat some bug spray that got on your food, you may get an upset stomach and even vomit, but you most likely won't die or get cancer.
  • If you get gasoline or motor oil all over your hands, or you swim in a Pool for hours that's overloaded with extra chlorine, you won't die or get cancer from it.
  • The mass media has scared the hell out of people so that Big Pharma can sell millions of toxic vaccines and flu shots.

"Now imagine that the fuel that's feeding those malfunctioning clone-soldier-making machines comes from several sources."



Reference:

//www.naturalnews.com/056063_causes_of_cancer_food_chemicals.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3556)


Look Younger With This Natural Facial Exfoliator
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Date: November 11, 2015 06:22 PM
Author: Darrell Miller
Subject: Look Younger With This Natural Facial Exfoliator

Diatomaceous Earth (also called diatomite) is a siliceous sedimentary rock. The rock is naturally occurring, soft and can be crushed into a fine powder. Like the name suggests, it is extracted from fossilized remnants of diatoms. Diatoms were tiny, hard shelled algae that lived in water. The diatoms skeletons comprise of silica, a natural substance. Over a long time, the diatoms collected on river, lakes and oceans sediments. Because of its fineness, DE acts as a great facial exfoliant. Besides silica, Diatomaceous Earth contains calcium, zinc, copper, magnesium, phosphorus and selenium. These minerals can be absorbed through the skin to complement your diet.


Diatomaceous Earth for Facial Exfoliation

The use of DE as a facial exfoliant is becoming very popular. Today, more than 150 products contain DE as the main ingredient. For facial exfoliation, make sure you use food grade DE. Food Grade DE differs from the DE used in the Pool filter. Food grade DE is finer (less abrasive and has been purified) than non-food grade DE.

It is easy to make a facial scrub. Simply mix the powder with enough water to make a paste. Be sure to apply the paste on your face immediately after preparing it. To increase its effectiveness as a facial exfoliator, rub the paste on your face with mild, circular motions. DE has abrasive properties which make it perfect for facial exfoliation.

You can use DE and water alone but for greater results mix DE with 1 tablespoon water, diluted honey or aloe vera juice and coconut oil. This way, not only do you remove microscopic dirt and oil deposits and dead skin but you also leave the skin moisturized. When massaging the paste to your face, refrain from applying it on the area around your eyes. The skin around the eyes is gentle and is often affected by powerful exfoliators and could lead to irritation. Leave the paste for a couple of minutes and use lukewarm water to rinse it off.

Diatomaceous earth looks cylindrical under a microscope. It is also known to carry a negative ionic charge that scientists claim to be the reason why pathogens are attracted to it and carried out of the body.

Diatomaceous Earth

Benefits of Diatomaceous Earth as a Facial Exfoliator

DE is a naturally occurring ingredient. This means there are no side effects associated with its use. Food grade diatomaceous earth has anti-fungal properties. It acts as a detoxification agent and leaves the skin refreshed and clean. It is a nourishing, lightening and brightening facial exfoliator. It increases the elasticity of the skin and leaves the skin radiant. Diatomaceous earth has been tailored to boost skin immunity and act as an anti-oxidant to fight free radicals. Not only does DE rid your face of dead skin cells but also helps the skin fight premature signs of aging.

Salt and sugar scrubs are effective in facial exfoliation but they are too abrasive to be used every day. Diatomaceous earth is finer and thus a great alternative. You may choose to make a DE paste at home or a buy a product that contains DE (among other natural products).

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3231)


What Is GMO and Why Should We Avoid It?
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Date: June 21, 2014 02:40 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Is GMO and Why Should We Avoid It?

Cause of GMO

gmoGMO's have been classified by the American Academy of Environmental Medicine as unhealthy, they were able to prove that GMO when ingested can cause organ damage, gastrointestinal as well as immune system disorders. This is due to the fact that GMO contains materials that are left behind the body, it can cause long term problems like accelerated aging as well as infertility. The genes inserted into a genetically modified crop like corn, can get transferred into the DNA of bacteria that is living inside the human body, this interaction can lead to a number of long term health problems.

Negative effects of genetically modified products have been observed in 1996, this was due to the number of Americans expressing a number of illnesses after consuming foods that have been engineered for 9 years.

Allergies increased including digestive problems and autism, while other research has yet to support this claim, many non-profit organizations such as Greenpeace are already making campaigns against the production of GMO infused crops and meat.

What are the other negative impacts of GMO?

1. Cancer causing components - GMO according to the American Public Health Association and American Nurses Association, have stated that the growth hormone present from cow’s milk treated by hormone IGF-1 can lead to cancer.

2. Long term negative effects on the body - GMO components can contaminate forever, it can cross pollinate, and the seeds can travel. Once it infects a certain area, it can contaminate the entire gene Pool. This means, that the health of future generations is already compromised and for this reason, the production has to be stopped right away before it infects more population.

3. Dangerous side effects - the mere process of creation of GMO's can produce toxins, carcinogens, allergens and nutritional deficiencies.

The direct production and consumption is already endangering a number of species including bees.

Many governments continue to remain lax about the issue, GMOs are illegally being sold and created in many countries, and people need to learn as much as they can in order to learn how they can prevent GMO products from entering their market.

Sources

//www.responsibletechnology.org/10-Reasons-to-Avoid-GMOs

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3138)


Can Butcher's Broom Boost Cardiovascular Health?
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Date: October 30, 2013 09:48 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Can Butcher's Broom Boost Cardiovascular Health?

 

Where to find Butchers Broom


butchers broomThe butcher’s broom also known as ruscus aculeatus is an evergreen low shrub that grows in the Eurasian region. It is known to produce greenish flowers that are small sized and blooms during Spring. It has leaves that produce red berries after the falling off of its female flowers. It is reputed among native cultures as much as asparagus, with the roots been eaten in various preparations.


It is mainly recurrent in woodland as a result of bird-spread though is now grown as a garden plant in regions across the world. It has general names like the pettigree, Jews’myrtle, sweet broom, petit houx and knee holly. Its roots are deployed as medicines in different remedies.


Application


It has been used as an effective tool to constrict capillaries and blood vessels by herbal and alternative medicine practitioners. Its efficiency in constricting blood vessels is considered to result from the constituent chemicals. This prevents the veins from Pooling blood thereby improving the flow of blood in the hands, brain and legs.

It has been used to heal fractures and reduce swelling, as well as treatment for hemorrhoids and gallstones. It is reputed for constipation relief and ease of urine ejection.


Result


As a result of its wide application and effectiveness, the German Health Commission listed it as a useful for the treatment of hemorrhoids. It is advised in medical circles that its use by pregnant women should be subject to consultation of a qualified medical practitioner to avoid possible contraindications and safeguard the fetal balance.


Clinical research is still open in several fronts to ascertain its virility and possible side effects as a result of the widespread usage across the globe by alternative medicine practitioners for a variety of medical conditions. This evidently will provide clues as to acceptable dosage and prescription in the years to come.


References:


1. //www.rxlist.com/butchers_broom-page2

2. //en.wikipedia.org/wiki/Ruscus_aculeatus

3. //www.webmd.com

4. botanical.com: Broom, Butcher's

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2866)


How D-ribose boost energy levels in the body
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Date: October 27, 2013 09:40 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How D-ribose boost energy levels in the body

D-ribose is a simple sugar, prontose sugar, or 5-carbon monosaccharide. It is used by all body cells and is essential component in energy metabolism. Ribose also gives the structural backbone of body genetic materials like RNA and DNA, certain vitamins and other vital cellular compounds. It provides raw material to facilitate the production of adenosine triphosphate.

D-ribose was discovered in late 1990s by an American company. People who were suffering from fatigue and chronic related illnesses could be given pure adenosine triphosphate instead of AMP. This new supplement was produced in a stable and safe natural form that allowed it to be sold as nutritional supplement.

Ribose is an essential ingredient in stimulating the production of natural energy. It promotes the cardiovascular health, minimizes cardiac stress associated with strenuous events. Ribose enables the muscles and heat to maintain healthy energy level as well as accelerating the recovery of energy when body tissues are stressed by overwork, strenuous exercise, or disease. The physiological fuction of d-ribose is known as 5-phosphoribosyl-1-pyrophosphate, which controls the metabolic path that synthesizes energy components in all body living tissues. In case the cellular energy Pool is depleted by overwork, diseases or exercise it must be replaced. 5-phosphoribosyl-1-pyrophosphate will stimulate the metabolic pathway to replenish these energy Pools.

Patients with myocardial ischemia condition or reduced blood flow resulting from reduced oxygen flow to the heart may experience discomfort and chest pain. This may cause heart attack to a person with such experience. The ability of the heart cells to expand and contract depend upon the adenosine triphosphate available. The reduced blood flow lowers the level of adenosine triphosphate, but this can as well be replenished by 5-phosphoribosyl-1-pyrophosphate. D-ribose stimulates the 5-phosphoribosyl-1-pyrophosphate production, which in turn increases the level of adenosine triphosphate. This will actually restores the heart cell contractile functions and reduces ischemia.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2861)


Can Butcher's Broom Help Fight Varicose Veins?
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Date: January 11, 2013 12:36 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Can Butcher's Broom Help Fight Varicose Veins?

Varicose Veins are abnormally thick veins that are twisted and enlarged. This problem occurs mostly in the leg and thigh veins. The thickened and twisted veins are called varicose veins. They can occur anywhere, but they mostly form in the legs because the legs work against gravity. Standing all day can increase the pressure on leg veins and cause varicose veins.

Causes

The normal function of veins is to carry blood from the outer body parts to the heart and lungs. The veins are provided with one-way valves, which prevent the blood from flowing backward within the vein. Defective or damaged valves are the main reason for varicose veins, as they allow the blood to flow backward, when it should be actually flowing up towards the heart. As the muscles contract to empty the veins, pressure builds up and this causes in the flow of more blood in the wrong way. Thus the pressure on the veins is increased and this causes varicose veins.

Factors that Aggravate Varicose Veins

  • * Pregnancy: During pregnancy, the blood volume increases and the growing uterus adds to the vein pressure in the legs, moreover, estrogen and progesterone relax the vein walls. All this lead to varicose vein formation during pregnancy
  • * Standing for long
  • * Obesity
  • * Straining: Any bodily condition, such as chronic cough, chronic constipation or urinary retention, which may cause strain can increase the chances for varicose veins.
  • * Age: Mostly elderly people are more prone to varicose vein occurrence.
  • * Surgery or trauma: Surgery can sometimes interrupt in the normal flow of blood.

Treatment

There are different types of treatments available to shrink varicose veins and to improve circulation, from simple home remedies to surgeries or medications for severe cases. Natural supplements like Butcher's broom are considered to be a very effective treatment for varicosities.

Butcher's Broom

Butcher's broom is a small, clump-forming evergreen shrub with tiny green flowers. It is an aromatic, diuretic and mildly laxative herb that helps reduce inflammation, increase perspiration and constrict the veins. The whole plant, young shoots and roots are used medically. Young shoots can be eaten like asparagus. It grows commonly in woodlands and hedgerows, and also on coastal cliffs. It is widely grown from Iran to the Mediterranean and the United States.

Its scientific name is Ruscus aculeatus, but it is commonly known as butcher's broom because butcher's used the stiff twigs to clean their cutting boards. The herb has been used for nearly 2000 years, but its medicinal uses have become common only from the last century. Investigations conducted in the 1950s indicated that butcher's broom can induce vasoconstriction and thus might be useful in treating circulatory diseases.

How It Works?

The two primary chemicals in butcher's broom, ruscogenin and neoruscogenin, can cause the blood vessels to narrow or constrict. Their anti-inflammatory properties help improve blood circulation in legs by preventing Pooling of blood and reduce swelling.

  • * The flavonoids and ruscogenins in butcher's broom cause the vessels to constrict, reduce blood collection and protect the capillaries. It strengthens blood vessels and improves circulatory health.
  • * Butcher's broom helps the blood vessels to release the accumulated blood, and thus reduces the size of the veins.

Therapeutic Uses

Butcher's broom is used internally to treat venous problems that vary from varicose veins to hemorrhoids. It is also used to strengthen the veins and capillaries. Butcher's broom may be the best natural solution for varicose vein treatment, because it helps with blood flow and circulation.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2810)


What Herbs Are Vein Strengtheners?
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Date: September 28, 2011 02:17 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Herbs Are Vein Strengtheners?

Blood vessels can be found all over the body. It is the passageway of blood so that cellular oxygenation as well as elimination of harmful substances from the cells would be successful. Blood vessels have three types, namely the arteries, the veins and the capillaries. Arteries contain the blood from the pulmonary system which is highly oxygenated while the veins consist of blood which is deoxygenated and abundant in cellular waste. Capillaries serve as a bridge between the two major blood vessels. Among these blood vessels, the veins are the only of its kind which has valves. These valves prevent backflow of blood since the direction of the blood in the vein is against gravity. Therefore, it is of no surprise that among the three types of blood vessels, veins are the most commonly damaged. In this article, we will be discussing of natural ways or herbs which are effective as vein strengtheners.

1. HORSE CHESTNUT. Traditionally, this herb has been used for the improvement of health the veins. In fact, Western medicine has considered this herb as the most effective herbal medicine for venous problems most especially Chronic Venous Insufficiency. It can improve venous return by improving the ability of the valves of veins to return blood to the heart from the lower extremities. This herb has also been found to decrease permeability of the capillary wall permeability thus lessening fluid outflow into tissues. The recommended dosage for this supplement is 500 mg each morning.

2. GOTU KOLA. Gotu kola is a popular herbal medicine of the Indian Ayurvedic medicine. It is also considered to be one of the oldest herbal medicines all over the world. This herb has been found to be effective in improving the tone, flexibility and integrity of the blood vessels. Therefore, this herb has been long used as a treatment for circulatory problems most especially varicose veins. 200 milligram extract of this herb is usually suggested three times daily.

3. RUTIN. This is not an herb itself but a chemical substance which can be found in several plants. Rutin is considered to be a flavonoid which can be extracted from citrus peels, cranberries, asparagus and buckwheat. Clinical studies of this chemical compound have revealed that it be an effective relief treatment of damaged and edematous veins. This chemical can also be used for improving the strength of the capillaries thus lowering the risk of damage.

These are only some of the herbs which are found to be effective as vein strengtheners. These herbs can be made into a poultice and applied to the skin so that positive effect can be obtained. Along with these herbs, it is also important that you should exercise regularly. Elevate your legs, if possible, especially when lying down at hours of sleep. This would greatly help in promoting venous return thus thwarting blood Pooling at the lower extremities. It is also important that you should avoid long time standing or sitting. Health experts also suggest that people must avoid prolong crossing of legs and not to wear tight clothing and foot wears since this can possibly constrict veins..

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2466)


Why Is The Amino Acid Tyrosine So Good for the Brain?
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Date: June 18, 2011 12:20 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Why Is The Amino Acid Tyrosine So Good for the Brain?

Tyrosine is an amino acid that serves as an immediate precursor to several organic compounds found in the brain and the central nervous system. It is one of the 20 amino acids utilized by cells in protein synthesis. As such, it is an important component of the human diet, albeit not classified as an essential nutrient. Mental infirmities not related to age has been linked to tyrosine deficiency.

There is no daily value for tyrosine, but it is an integral part of proteins obtained from both animals and plants. Also, supplementation of tyrosine has not shown any adverse effects. That being said, deficiency in tyrosine is not unheard of. In fact, there is a rare autosomal recessive disorder called phenylketonuria that interferes with the synthesis of tyrosine and leads to brain damage and seizures.

Prevents Brain Damage

Tyrosine is one of the amino acids necessary for the manufacture of neurotransmitters and proteins that display vital functions in the nervous system. In phenylketonuria, the synthesis of tyrosine from phenylalanine is impaired, causing the build-up of the latter. High concentrations of phenylalanine deprive the brain of other amino acids, such as tyrosine. This results in progressive mental retardation.

The presence of tyrosine in the central nervous system is very important in mental development. It works as nutrient for nerve cells that powers neuronal activities. Not surprisingly, regular intake of tyrosine has been observed to display cerebroprotective properties. It has also been linked to the prevention of headaches following an intense physical activity.

Improves Stress Tolerance

It has long been suggested that supplementation of tyrosine may improve stress tolerance, but studies that support this claim have surfaced only recently. High levels of tyrosine in the brain appear to improve physiological responses to stress in both animal and human studies. Many researchers believe that depleting levels of tyrosine in times of stress contribute to mental fatigue.

NOW - TYROSINE 500mg

Tyrosine is a precursor to catecholamines, organic compounds that function as neurotransmitters and hormones. It is converted to epinephrine, or adrenaline, which is responsible for the activities in the peripheral nervous system during stress. It is also converted to norepinephrine, which sends signals to both sides of the brain and forms a neurotransmitter system within the brain and the spinal cord.

Promotes Mental Clarity

Tyrosine plays a role in sustaining mental clarity, the reason why it is thought to produce nootropic effects. For one, the availability of tyrosine in the brain improves mental function, especially under psychological stress. It is utilized by the brain in the manufacture of brain chemicals involved in cognitive function and even motor skills.

More importantly, tyrosine provides a ready Pool of levodopa, which increases dopamine levels. Both tyrosine and dopamine levels have been observed to be low in individuals suffering from clinical depression, suggesting that tyrosine may provide mood-altering effects. Since there is no harm in regular intake of tyrosine, it has been promoted as an alternative to other mood enhancers.

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Butcher's Broom Extract
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Date: May 02, 2008 11:04 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Butcher's Broom Extract

Butcher’s broom (Ruscus aculeatus) is a member of the lily family, and looks a bit like a holly bush with barbed evergreen leaves and bright red berries in the fall. At one time they were collected, tied together and sold to butchers as brooms to sweep out their shops.

The stiff leaves were particularly suitable for cleaning out offal and other waste products from butchered animals and also for scrubbing butcher’s blocks. It was also used as a deterrent to rodents with their eyes on the meat! Alternative names are sweet broom, kneeholy and Jew’s myrtle, so named because it was used during the Feast of the Tabernacles as one of the ‘four species’ used in the lulav.

The herb was commonly used in Ancient Greece and Rome, the Greeks using it to reduce swellings of various kinds and the Romans using it to treat varicose veins. It has the same uses today, only the mechanisms are understood better. It has been used for centuries in the Mediterranean area for the treatment of inflammations and problems with the circulation, and the Romans used to mash up the leaves and berries to add to wine, and they also used the roots and rhizome as a medicine by soaking them in wine. Today, it is illegal to use holly as a decoration in Italy, so butcher’s broom is used instead.

All parts of the plant are used, including the rhizome, and although it is used as a diuretic, and to control a loss of blood pressure experience by some people on standing up, it is its effect on blood vessels where its main medical benefits lie. Butcher’s Broom can strengthen certain portions of blood vessels, and change the flexibility properties of the cell walls.

The result of this is that the vessels are tightened up, which helps to maintain the flow of blood throughout the body, but also renders the cell walls less likely to leak or crack under stress. The result is a reduction in blood leakage from stretched and weakened blood vessels such as those that result in hemorrhoids, and also of conditions caused by weakened valves in the veins such as varicose veins and spider veins.

The blood pressure in the veins is very weak since they are so far away from the heart, the blood having passed through the arteries, through the capillaries and into the veins on its way back to the heart before being pumped to the lungs. When the valves become weakened, particularly in the large veins in the leg, there is little to prevent the blood from coming under the influence of gravity and Pooling back down the vein, causing distention and occasional ruptures.

A ruptured varicose vein can be very serious and cause significant blood loss. Weakened valves can also lead to the formation of blood clots, which is itself a very serious condition that eventually blocks the heart or causes a stroke. Not only can butcher’s broom strengthen the vein walls and prevent leakage, and also enable them to more easily resist the pressure that can cause them to rupture, but it can also be used to break down blood clots. In fact the herb is used in many European hospitals to prevent the formation of blood clots after surgery.

The active ingredients in the rhizome are saponins that contain the aglycones ruscogenin and neuroscogenin and the associated spirostanol and furostanol glycosides. The receptors that cause vasocontraction are known as adrenoreceptors, these receptors can be selectively stimulated by butcher’s broom extract to tighten the veins and improve the return of blood. When introduced intravenously, butcher’s broom was noted to constrict venules (small veins that feed the main veins but not arterioles (the small arteries than feed the capillaries). Hence blood vessels can be selectively treated, and the effect on isolated blood vessels was enhanced by heating. Many supplements include calcium that helps to strengthen the blood vessel walls.

It is possible, therefore, to target the blood vessels that require constrictive treatment in order that they are strong enough to return blood to the heart rather than leak or distend. However, that is not the only health benefit that butcher’s broom provides. It can also be used as a diuretic. It is not a strong diuretic, but is used to relief the swelling of bruises and PMS, the reason given being that since leakage from the blood vessels is lessened, then more fluid is available to pass through the kidneys. There might be other reasons.

It is also use for the treatment of ortho static hypotension, the reduction in blood pressure that some people experience. It is believed that butcher’s broom can control this condition without increasing blood pressure, as most other remedies do, and which is almost as undesirable as the condition they are treating.

There are few problems associated with the herb, although few studies have been carried out its use by pregnant women. Although the one test that was carried indicated no effect, it would be wise for pregnant or nursing women not to use it until further studies have been carried out. Due to its effect in tightening blood vessels, its use is not recommended by anybody suffering from high blood pressure (hypertension). Many hypertension treatments are designed to render the blood vessels more elastic rather than constrict them.

In one very small study of pregnant women who used a topical cream containing butcher's broom, no side effects were seen for either the mother or the baby. However, very little information is available on how oral butcher's broom might affect a developing fetus, an infant, or a small child. Therefore, its use is not recommended during pregnancy, while breast-feeding, or during early childhood.

Because it tightens blood vessels, butcher's broom may worsen high blood pressure or benign prostate hyperplasia (BPH). Individuals with either of these conditions should not use any form of butcher's broom without first consulting a doctor. The known side effects have already been stated, and they are fairly mild, but few studies have been made on the herb other than in Europe, and the side effects have not been fully explored. It is unlikely; however, that there are any as yet unknown serious side effects since butcher’s broom has been used now for a long time, particularly in Europe.

The term ‘ruscogenin’ is used for the collective mixture of active saponins in butcher’s broom, and many of the supplements are formulated to include from 5 to 15 mg of these. However, check the label, since standardization is not yet required in the USA, and in theory a preparation can include much more or much less ruscogenin. It is frequently supplied with other active ingredients, such as vitamin C or calcium, and perhaps even horse chestnut that affect blood vessels in a similar way. Always follow the instructions on the package, since these are designed for the specific strength of supplement you are using.

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Ubiquinol Reduced CoQ10
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Date: April 07, 2008 01:05 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Ubiquinol Reduced CoQ10

Ubiquinol, which is the reduced from of Coenzyme Q10 (CoQ10), has been recently added to the supplement offerings of many companies and has generated a lot of confusion along with its excitement. As a supplement, ubiquinol is somewhat new, but as a critical part of human metabolism, our knowledge of ubiquinol goes back to the discovery of CoQ10. Although CoQ10 is often thought of as a “static” nutrient in the context of nutrition, it actually interchanges between two useful states: the oxidized ubiquinone, and the reduced ubiquinol.

Coenzyme Q10 is a member of a family of important biological compounds which are referred to as ubiquinones. It is a lipophilic, water-insoluble substance, which takes part in a large array of biochemical oxidation and reduction reactions. It was first identified in 1957 as an essential component of the energy production system in cells. CoQ10 and other members of the ubiquinone family have, since then, been identified as critical metabolic compounds in a range of aerobic organisms. Because of its crucial role in metabolism, humans have the ability to make their own CoQ10, although small amounts can be obtained through diet and as supplements.

In humans, CoQ10 is found in each cell in the body, but is particularly abundant in tissues which have large energy requirements such as the heart, liver, kidneys, and skeletal muscles. Smaller amounts can be found in the brain, lungs, and intestines. There are also substantial amounts that can be found in circulation, which are most often associated with lipoprotein particles. In total, CoQ10 in a normal adult has been estimated to be between 0.5 and 1.5 grams. Inside cells, about half of the CoQ10 is found within the mitochondria, where the final steps of CoQ10 production occur.

CoQ10 which is not located in areas of the cell and are not charge with producing cellular energy can amount to about 50-60 percent of the total CoQ10 Pool. CoQ10 can be found throughout cell membranes and in other cellular structures such as the nucleus, cytoplasm, and endoplasmic reticulum. Some experimentation has also concluded that, while the final steps of CoQ10 production occur in the mitochondria, it can be exported to other sub-cellular locations.

While participating in various oxidation and reduction reactions, CoQ10 is cycled between two stable states: a fully oxidized form referred to as ubiquinone, and a fully reduced form called ubiquinol. CoQ10 cycles through these oxidated/reduced forms in order to achieve its metabolic goals. The cycle of CoQ10 is simple. Ubiquinone picks up electrons and then becomes ubiquinol. Ubiquinol then release its electrons and becomes ubiquinone again. Therefore, it would seem that CoQ10 has a very simple function of moving electrons, as the transfer of electrons is a fundamental step in the production of energy, the regeneration of antioxidants in cell membranes, and the construction of other important biological molecules. Each cell that is in the body needs a source of energy in order to survive. Therefore, sugars, fats, and amino acids are broken down in order to make energy.

In the mitochondria, CoQ10 is abundant, as it carries electrons to aid in the chemical reactions that burn cellular fuel and produce chemical energy to form ATP. Since substantial amounts of ATP are needed to power our cells, the importance of CoQ10 in human metabolism is easily understood. Both forms of CoQ10 are needed to transfer electrons between energy-producing reactions. Outside of the mitochondria, CoQ10 performs a slightly different role as a membrane and antioxidant. About half of the human body’s total CoQ10 Pool may be functioning in this capacity. CoQ10 is one of the major antioxidant elements of the LDL particles and is also one of the first to be depleted when LDL is subjected to oxidation.

A discussion of CoQ10 would not be complete without mentioning its documented health benefits. Supplemental CoQ10 has been the subject of a lot of studies over the last half century, especially in applications for cardiovascular health. Many studies have shown benefits of CoQ10 in patients who are diagnosed with chronic heart failure, exercise-induced angina, hypertension, or those who have recently experienced infarction. There is also early evidence showing that CoQ10 may protect the heart from damage during chemotherapy, bypass surgery, or in diabetes. Aside from its cardiovascular uses, CoQ10 has been studied for its benefits in other conditions involving dysfunctions in cellular energetics, neurological degeneration, or oxidative stress damage. Although the clinical evidence for the potential benefit of CoQ10 in many of these applications shows promise, the variability in study outcomes proves it necessary to further research these areas for a more definite answer.

As we have previously seen, CoQ10 functions by cycling between two stable forms, ubiquinol and ubiquinone. This cycle results in the generation of cellular energy and the protection of membranes and lipids from oxidation. Dietary or supplemental CoQ10 also takes part in this cycle. Supplemental ubiquinol may have a distinct advantage over ubiquinone in its facility of absorption. Like many fats and lipophilic nutrients, CoQ10 is usually taken up by the intestinal electrolytes, packaged into lipid particles, and then released into the lymphatic system. From there, these particles are transferred into circulation where they are free to be transported throughout the body as needed.

The absorption of dietary CoQ10 is actually quite poor since it has limited solubility in lipids and depends on other contents of the gut. Some studies have measured that absorption is as low as 2-3 percent of the total dosage. One of the most thrilling consequences of the development of a stabilized dosage form of ubiquinol is its ability to be absorbed more efficiently than ubiquinone. There is evidence that CoQ10 must be reduced in intestinal enterocytes before the release into the lymphatic system. This, paired with absorption/reduction, may be a rate-limiting step of CoQ10 assimilation.

Dietary ubiquinol avoids this reduction reaction, and is directly available for absorption, which explains why ubiquinol-based CoQ10 supplements exhibit enhanced bioavailability over ubiquinone supplements. Preliminary studies in humans have shown that absorption of ubiquinol is at least double the absorption of ubiquinone. Comparisons of blood levels between trials also estimate the improvement in absorption to be significantly higher. Future studies are necessary to more accurately determine ubiquinol’s enhanced absorption, and what effect the patient age or medical condition may have on these results.

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Boost Beauty with Vitamin Supplements
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Date: November 15, 2007 03:55 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Boost Beauty with Vitamin Supplements

Vitamin A

Vitamin A can help reduce the effects of sun damage and rosacea appearance. Rosacea is a skin condition where enlarged blood vessels make the face red and blotchy. Vitamin A can help the body reduce the production of sebum aiding in acne control. Vitamin A is needed to help the body regulate the growth and shedding of skin cells from the skins surface. Taking your vitamin A on a daily basis is important.

Vitamin B Complex

B vitamins can stimulate wound healing in the body as well as help fight acne breakout. Topical B-5 or pantothenic acid can penetrate and moisturize the skin strengthening and softening the skin preventing the skin from drying out as quick helping it live longer amd look healthier.

Vitamin C

Vitamin C has been well documented as an antioxidant and may help health wounds in the body as well. Vitamin C can help reduce the affects of UV light exposure from the sun which reduces wrinkles from sun damage. Vitamin C has been studied to boost collagen production in the skin. Collagen keeps the skin soft and flexible. Because vitamin C neutralizes oxidants in the body, vitamin C can help fight oxidation of the skin from sun damage and help one retain their youthful look.

Zinc

Zinc can aid in the reduction of scarring and is used as a natural sunscreen most commonly seen at the swimming Pool. Vitamin A and Zinc work together to help keep the skin looking younger, and recent studies suggest zinc acts like an anti-inflammatory on the skin when applied topically.



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Ubiquinol
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Date: October 24, 2007 11:37 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Ubiquinol

Benefits

Ubiquinol has powerful antioxidant actions in target cells *

 

Although ubiquinone (oxidized coenzyme Q10) and ubiquinol (reduced coenzyme Q10) are kept at a constant ratio within the body, the majority of the total coenzyme Q10 Pool is made up of ubiquinol.  In fact, when ubiquinone is taken orally, much of it appears to be rapidly converted into ubiquinol. 1,4 Ubiquinol functions as a potent antioxidant in humans, including in low-density lipoproteins (LDLs) where it protects them from oxidative damage.1,4,5 The coenzyme Q10 molecule can be found in all membranes throughout cells.6 It appears to works in conjunction with both vitamin E and vitamin C to provide antioxidant actions throughout the body.7

 

Coenzyme Q10 supports mitochondria to enhance cellular energy production*

 

Coenzyme Q10, with its widespread distribution throughout the body, plays a crucial role in mitochondrial physiology as a critical member of the electron transport chain. This transport chain, which is part of cellular respiration, leads to the formation of adenosine triphosphate (ATP), our body’s primary energy source.  Levels of this key nutrient may decline as a healthy person ages.7,8  Animal studies have found that supplementation can restore normal levels in certain tissues 6, and human studies suggest that supplementing with this enzyme may have increased benefits when a person has depleted levels. 7

 

Coenzyme Q10 supports healthy heart functioning*

 

Concentrations of coenzyme Q10 are understandably high in the heart as these muscle cells require high levels of energy to constantly function optimally. A number of studies (both animal and human) strongly suggest that coenzyme Q10 supplementation is supportive for healthy heart functioning and for maintaining cardiovascular system health.7,9

 

Ubiquinol has been studied for safety and bioavailability in humans*

 

A recently published single-blind placebo-controlled study in healthy subjects found no safety concerns in people who took Kaneka’s QH ubiquinol supplement orally at doses of up to 300 milligrams daily for up to four weeks.4 Single oral doses of either 150 milligrams or 300 milligrams were given to fifteen healthy men and women, and standard laboratory testing (including hematology, blood chemistry, and urinalysis) as well as physical examination and electrocariography (EKG) results showed no clinically significant changes when tested two days after supplementation as compared to before the taking the supplement. In addition to the single dose study, 80 healthy volunteers were given either placebo, 90, 150 or 300 milligrams of ubiquinol each day for four weeks, and again no clinically significant differences were seen in any of the testing parameters after two and four weeks of supplementation, nor were there differences two weeks after discontinuation of the supplement.  By monitoring levels in the blood, the authors found that ubiquinol was well absorbed.4

 

Studies in several animals also reveal no concern of toxicity in doses of ubiquinol up to 200 milligrams per kilogram of body weight for up to thirteen weeks.4 When compared to humans, this dose level is enormously higher than the recommended doses.  Supplementation with ubiquinol appeared to be safe at even higher levels (up to 600 milligrams per kilogram body weight) in a study using a different animal. In vitro assays additionally found no safety concerns for the use of ubiquinol, as it was found to be non-mutagenic and did not cause damage to chromosomes in cells.

 

Safety

Suggested Adult Use: Take one softgel daily with food, or as directed by a nutritionally informed physician.

 

Scientific References

1.    Mohr, D., V.W. Bowry, and R. Stocker, Dietary supplementation with coenzyme Q10 results in increased levels of ubiquinol-10 within circulating lipoproteins and increased resistance of human low-density lipoprotein to the initiation of lipid peroxidation. Biochim Biophys Acta, 1992. 1126(3): p. 247-54.

 

2.    Weber, C., et al., Effect of dietary coenzyme Q10 as an antioxidant in human plasma. Mol Aspects Med, 1994. 15 Suppl: p. s97-102.

 

3.    Okamoto, T., et al., Human serum ubiquinol-10 levels and relationship to serum lipids. Int J Vitam Nutr Res, 1989. 59(3): p. 288-92.

 

4.    Hosoe, K., et al., Study on safety and bioavailability of ubiquinol (Kaneka QH) after single and 4-week multiple oral administration to healthy volunteers. Regul Toxicol Pharmacol, 2007. 47(1): p. 19-28.

 

5.    Stocker, R., V.W. Bowry, and B. Frei, Ubiquinol-10 protects human low density lipoprotein more efficiently against lipid peroxidation than does alpha-tocopherol. Proc Natl Acad Sci U S A, 1991. 88(5): p. 1646-50.

 

6.    Crane, F.L., Biochemical functions of Coenzyme Q10. Journal of the American College of Nutrition, 2001. 20(6): p. 591-598.

 

7.    Jones, K., et al., Coenzyme Q-10 and cardiovascular health. Alternative therapies, 2004. 10(1): p. 22-31.

 

8.    Schulz, C., et al., Comparison of the relative bioavailability of different coenzyme Q10 formulations with a novel solubilizate (Solu Q10). Int J Food Sci Nutr, 2006. 57(7-8): p. 546-55.

 

9.    Coenzyme Q10. Monograph. Altern Med Rev, 2007. 12(2): p. 159-68.

 



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The Awesome Foursome: Coenzyme Q10, D-Ribose, L-Carnitine, and Magnesium
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Date: May 18, 2007 01:06 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The Awesome Foursome: Coenzyme Q10, D-Ribose, L-Carnitine, and Magnesium

The Awesome Foursome: Coenzyme Q10, L-Carnitine,

D-Ribose, Magnesium

 

The “Awesome Foursome” of Coenzyme Q10, L-Carnitine, D-Ribose, and magnesium helps our hearts metabolize energy more efficiently and protects them from the stress of cardiovascular disease. This powerful combination of nutrients goes directly to the basic biochemistry of cellular energy metabolism. Now let’s take a closer look at how Coenzyme Q10, L-Carnitine, D-Ribose, and magnesium work in synergy to promote cardiovascular health.

 

Coenzyme Q10:

Energy Recycling through the Electron Transport Chain

Coenzyme Q10 is a powerful antioxidant that helps protect the mitochondrial membrane, mitochondrial DNA, and cell walls from free-radical attack. But its most important function in the body is its central role in energy metabolism.

Most – about 90 percent – of the ATP used by cells is recycled as food (fuel) and oxidized in the mitochondria. Fatty acids, carbohydrates, and, occasionally, proteins are carried across the mitochondrial membrane and enter the Krebs’ cycle, moving from step to step and spinning off electrons. These electrons are then handed off to the electron transport chain, where, in the presence of oxygen, the energy from the electrons is captured as a phosphate group is added to ADP to form ATP. This recycling of ATP is called oxidative phosphorylation, and the by-products of these pathways are CO2 and water.

In this fashion, Coenzyme Q10 acts as a gatekeeper of electrons, making sure they are carried to just the right place to pass on their life-giving energy.

What is critical, however, is the simple fact that without Coenzyme Q10 the electron transport chain would totally break down. And since the electron transport chain is (by far!) the largest contributor to cellular energy turnover, its loss would be catastrophic. It is also important to know that there has to be an excess of Coenzyme Q10 in the mitochondria to be maximally effective. Having just enough isn’t sufficient to do the job properly, and having a deficiency seriously affects the mitochondria’s ability to supply the cell with energy.

Cellular stress can cause Coenzyme Q10 deficiency, which places a severe strain on Coenzyme Q10 availability. People with heart disease, hypertension, gingival disease, Parkinson’s disease, and the other disorders we’ve discussed are known to be deficient in Coenzyme Q10. Whether these deficiencies are the cause or the effect of these varied medical problems, the end result is that they sap the life out of their mitochondria and reduce their energy supplies. You see, Coenzyme Q10 cannot function properly if electrons are not coming out of the Krebs’ cycle, and the Krebs’ cycle won’t work without the fuel that’s transported into the mitochondria by L-Carnitine.

 

L-Carnitine:

Transporting the Cellular Energy Fuel

Fatty acids are the preferred energy fuel for hearts and most other cells in the body. L-Carnitine facilitates the beta oxidation of fatty acids as energy fuel. And since fatty acids are the preferred fuel for energy recycling in cells, this action is critical to cell and tissue function. Unfortunately, L-carnitine is deficient in people with heart disease, peripheral vascular disease, lipid metabolic disorders, mitochondrial disorders, and many other disease syndromes we reviewed earlier. This L-carnitine deficiency disrupts the normal metabolism of fatty acids, reducing available energy supplies and leading to the accumulation of toxic by-products of fatty acid metabolism. L-carnitine supplementation revives fatty acid metabolism and restore normal mitochondrial function. But even this powerful improvement in cellular energy metabolism cannot up for the energy drain that comes from the loss of energy substrates caused by low oxygen delivery to the tissue. Only D-Ribose can do that.

 

D-Ribose:

Rebuilding the Cellular Energy Pool

As long as cells and tissues have plenty of oxygen, the Pool of energy substrates in the cell remains high. And as long as there is enough L-carnitine and Coenzyme Q10 available, the process of energy utilization and supply can proceed unimpeded. However, the cellular supply of oxygen can be restricted by acute or chronic heart disease, peripheral vascular disease, any number of skeletal – or neuromuscular diseases, or even high-intensity exercise.

When cells are deprived of oxygen the mitochondrial energy turnover becomes inefficient. Remember, oxygen is required to let the oxidative pathway of energy recycling work properly. If the mitochondria are not able to recycle energy efficiently, cellular energy supply cannot keep pace with demand. But the cell has a continuing need for energy so it will use all its ATP stores and then break down the by-product, adenosine diphosphate (ADP), to pull the remaining energy out of this compound as well. What’s left is adenosine menophosphate (AMP). Since a growing concentration of AMP is incompatible with sustained cellular function it’s quickly broken apart and the by-products are washed out of the cell. The net result of this process is a depletion of the cellular Pool of energy substrates. When the by-products of AMP catabolism are washed out of the cell, they are lost forever. It takes a long time to replace these lost energy substrates even if the cell is fully perfused with oxygen again.

Ribose is the only compound used by the body to refill this energy Pool.  Every cell in the body has the capacity to make ribose, but hearts, muscles, and most other tissues lack the metabolic machinery to make ribose quickly when the cells are stressed by oxygen depletion or metabolic insufficiency.  Ribose is made naturally in the cells from glucose.  In stressed cells, however, glucose is preferentially metabolized for the energy turnover and is not available for ribose synthesis.  So when energy Pools are drained from stressed cells, the cells must first wait for the slow process of ribose synthesis before they can begin to replace their lost energy stores.

    Acute ischemia, like that which takes place during a heart attack, heart surgery, or angioplasty, drains the cell of energy.  Even when oxygenated blood flow returns, refilling the energy Pool may take ten or more days.  But when oxygen deprivation is chronic, or when energy metabolism is disrupted by disease, there may be so much continual strain on the energy supply that the Pool can ever refill without the assistance of supplemental ribose.  Conditions like ischemic heart disease or congestive heart failure fall into this category.  In these situations, supplementing the tissue with exogenous ribose is the only way the cell can keep up with the energy drain.

 

Magnesium:

Switching on the Energy Enzymes

Magnesium is an essential mineral that's critical for energy requiring processes, in protein synthesis, membrane integrity, nervous tissue conduction, neuromuscular excitation, muscle contraction, hormone secretion, maintenance of vascular tone, and in intermediary metabolism.  Deficiency may lead to changes in neuromuscular, cardiovascular, immune, and hormonal function; Impaired energy metabolism; and reduced capacity for physical work.  Magnesium deficiency is now considered to contribute to many diseases, and the role for magnesium as a therapeutic agent is expanding.

    Magnesium deficiency reduces the activity of important enzymes used in energy metabolism.  Unless we have adequate levels of magnesium in our cells, the cellular processes of energy metabolism cannot function.  Small changes in magnesium levels can have a substantial effect on heart and blood vessel function.  While magnesium is found in most foods - particularly vegetables - deficiencies are increasing.  Softened water and a trend toward lower vegetable consumption are the culprits contributing to these rising deficiencies.

 

Supporting the Links in The Energy Cycle Chain – the Synergy

Clearly, each membrane of the “Awesome Foursome” is fundamental to cellular energy metabolism in its own right. Each plays a unique and vital role in supplying the heart with the energy it needs to preserve its contractile force. Each is independently effective in helping hearts work through the stress of disease. And while each contributes immeasurable to the energy health of the cell, in combination they are unbeatable. Allow me to reiterate the step-by-step, complicated cellular processes involved to be sure that you really understand the rationale for using these nutrients.

The cell needs a large, sustained, and healthy Pool of energy to fuel all its metabolic functions. Contraction, relaxation, maintenance of cellular ion balance, and synthesis of macromolecules, like proteins, all require a high energy charge to carry their reactions to completion. The energy Pool must be preserved, or these fundamental cellular functions will become inefficient or will cease to operate altogether. To keep the Pool vibrant and healthy, the cell needs ribose. But even with supplemental ribose, the cell needs the efficient turnover of its energy stores to balance ongoing energy utilization with supply. That’s where CoQ10 and L-carnitine come into play.

The converse is also true. Even if the cell is fully charged with energy, cellular energy supply will not keep pace with demand if the mitochondria are not functioning properly. CoQ10 and L-carnitine work to keep mitochondrial operations running at peak efficiency, and one side cannot work effectively without the other. Even though CoQ10 and L-carnitine can make the energy turnover mechanisms work more efficiently, they cannot increase the cell’s chemical driving force, and their action will be only partially effective. Ribose on the other hand, can keep the energy Pool supplied with substrate, but the value of energy Pool repletion cannot be fully realized if the substrate cannot be maximally utilized and recycled. Ribose fills the tank; CoQ10 an L-carnitine help the engine run properly.

Magnesium is the glue that holds energy metabolism together. By turning on the enzymes that drive the metabolic reactions, magnesium allows it all to happen.

These four nutrients must be utilized by cardiologists and other physicians as they treat patients day-to-day. On my own journey, using Coenzymes Q10 for two decades, L-carnitine for more than ten years, D-Ribose for two years, and magnesium equally as long, I’ve seen this “Awesome Foursome” reduce suffering and improve the quality of life for thousands of patients.

The future of nutrition in conventional medicine is very bright, although the integration of nutritional supplements has been a slow and, at times, lonely process.

L-carnitine and Coenzyme Q10 are finally gaining the recognition they deserve. D-Ribose is emerging as a new player in the complex understanding of metabolic cardiology, and doctors are beginning to discuss the important role of magnesium deficiency in heart patients. As a practicing cardiologist for over thirty years, I see metabolic cardiology as the future for the treatment of heart disease and other complex disease conditions, as well.



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Vitamin D May Show Benefits Against Breast and Colorectal Cancer
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Date: February 27, 2007 02:09 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Vitamin D May Show Benefits Against Breast and Colorectal Cancer

Review and meta-analysis of several studies led researchers from several institutions to determine that an increased daily intake of vitamin D may significantly correlate with reduced incidences of colorectal and breast cancer. The breast cancer study Pooled dose-response data from two earlier studies of 1,760 subjects. Subjects with the highest serum concentrations of 25-hydroxyvitamin D, or 25(OH)D (50 nanograms per milliliter), had a fifty percent lower risk of breast cancer compared to those with the lowest blood concentrations; less than or equal to 10 nanograms per milliliter. The colorectal cancer meta-analysis looked at fiver studies of 1,448 caucasian subjects. The authors estimate a two-thirds reduction in incidence with serum concentrations of 46 nanograms per milliliter, corresponding to a daily intake of 2,000 IU of vitamin D3. the researchers state the best way to achieve these concentrations is a combination of diet, supplements and 10 to 15 minutes per day in the sun. (Journal of Steroid Biochemistry Medicine, volume 32, Number 3, Pages 210-216)

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Med schools failing on nutrition teaching
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Date: September 19, 2006 05:45 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Med schools failing on nutrition teaching

Almost 60 percent of US medical schools do not meat recommendations for nutrition education for med students, producing physicians – the first port of call for nutrition advice for many consumers – who may have inadequate nutrition knowledge.

Twenty years ago the National Academy of Sciences (NAS) reported that 21 hours of education in nutrition was required but found that many medical schools did not offer nutrition courses.

Surveys show that hasn’t changed much, so it appears we are producing a Pool of physicians who feel largely unprepared to counsel their patients about nutrition.

“Sooner or later, everyone sits down to the banquet of consequences.” Robert Louis Stevenson.

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Sytrinol 150mg - Now Vitamins
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Date: August 29, 2006 03:14 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Sytrinol 150mg - Now Vitamins

Sytrinol 150mg – Cholesterol Formula

 

Now Vitamins Sytrinol is a revolutionary new dietary supplement that was carefully developed to help support healthy cholesterol and triglyceride levels.  This is made possible based on Sytrinol’s high concentration of polymethoxylated flavones (PMF’s) from citrus, palm tocotrienols and other proprietary constituents. Studies have shown that this novel blend of cardiovascular supporting compounds can help maintain cholesterol and triglyceride levels that are already within a healthy range.*

 

Polymethoxylated flavones, or simply PMF’s are a type of potent, highly active bioflavonoid commonly found in citrus fruits.  Tangeretin and nobiletin are two of the most potent, and their ability to support healthy cardiovascular function is backed by over 25 years of well-documented research.  In addition to the role they play in preserving the integrity of healthy cells, it has been theorized that Polymethoxylated flavones posses the ability to maintain healthy cholesterol levels.  They do this by inhibiting the formation of two key cholesterol building blocks – apolipoprotein-B and triglycerides.  Without these, the body loses its ability to construct LDL cholesterol, thus resulting in a more healthy total cholesterol Pool.

 

Palm tocotrienols, an equally beneficial component of Sytrinol, have also been shown to affect toe production of cholesterol.  Tocotrienols, like vitamin E, has strong antioxidant properties that allow it to protect cell membranes.  Additionally, they have been shown in studies to reduce blood platelet aggregation, inhibit the formation of arterial plaque and decrease the oxidation of LDL cholesterol.*

 

This potent combination is what ultimately allows Now Vitamins Sytrinol to provide exceptional lipid profile protection.  For added support, we’ve included 50mg of Milk Thistle, 50mg of Alpha Lipoic Acid and 10mg of Policosanol, per serving.

Serving Size 1 Vcap

Chromium………………………..…….60mcg

(from Chromium Chelavite® Amino Acid Chelate)

Sytrinol®……………………………....150mg

(Proprietary Blend of Natural Citrus and Palm fruit)

Milk Thistle Extract (Silybum Marianum)80%....50mg

Alpah Lipoic Acid…………………...…50mg

Policosanol (from Sugar Cane)……………….10mg

 

Sytrinol is a proprietary and registered trademark product of Source One Global Partners.

 

 



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Americans, on the whole, are fatter than just about any other group...
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Date: March 18, 2006 02:38 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Americans, on the whole, are fatter than just about any other group...

Americans, on the whole, are fatter than just about any other group of people in the world. They also have some of the highest rates of Type-II Diabetes and heart problems in the world. Why are we so fat? Weight gain is usually a combination of two things: an unhealthy diet and a lack of exercise. Most people, when they decide to try and lose weight, only tackle part of the problem. They try dieting or taking pills or living off of lemon juice and cayenne pepper for awhile, but usually it doesn’t work. Though a healthy diet is important to losing weight, it’s still only part of the equation. If you cut down your calories but still sit on a couch or in an office every day, you’re not going to lose much weight. Interestingly enough, though many people are happy to try dieting, there aren’t many who only work at the other side of the equation: exercising.

So why don’t people exercise? Part of it is attached to our mentality about exercising. “Exercising” brings up images of sweaty, unhappy people lifting weights in a smelly gym, and it sounds like a lot of work. However, exercising doesn’t mean you’re going to have to pump iron for a few hours every day. In fact, lots of things are considered exercising, from playing a pick-up game of basketball to gardening to just taking a walk around the block. Most studies have found that a half hour of exercise every day is enough to keep you healthy, and that half hour doesn’t even have to be all at once. You can skip rope for ten minutes in the morning, take a walk for ten minutes after lunch, and take a walk around the block for ten minutes when you get home and night and take care of all of your exercise for the day.

“But wait a minute,” you say, “How can walking be good for you? I walk every day!” The average American walks for only about 1/3 of a mile every day. However, fitness walking is a great way to lose weight, especially because it’s so available. If you want to go swimming you have to go to a Pool, change clothes, swim, change again, and go home or to work, but if you’re taking part in fitness walking all you have to do is walk out the door of your office. Fitness walking is also an attractive exercise choice because it’s low-impact and virtually injury-free, and serves as a nice warm up for running or jogging. Fitness walking is also easy to incorporate into any schedule, since if you walk fifteen minutes to work every morning and fifteen minutes back every evening you’ve already taken care of your exercise for the day, which will help you lose weight and stay healthy.

Solaray Sale - Ultimate Nutrition Sale - Action Labs Sale - Veg Life Sale - Kal Vitamins Sale

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Dr. Verghese, M.D. Liver Detoxifier & Regenerator Fact Sheet
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Date: December 07, 2005 12:16 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Dr. Verghese, M.D. Liver Detoxifier & Regenerator Fact Sheet

Dr. Verghese, M.D. Liver Detoxifier & Regenerator Fact Sheet Neil E. Levin, CCN, DANLA 02/10/05

LIKELY USERS: People with exposure to toxins that stimulate liver activity; People with exposure to infections that may have damaged liver tissue

KEY INGREDIENT (S): Milk Thistle extract (Silymarin), Glutathione, NAC, Bupleurum extract, Grape Seed Extract, Dandelion Root extract, Artichoke Leaf, Schisandra and about a dozen additional herbs, along with synergistic ingredients

MAIN PRODUCT FEATURES: This formula was developed by a physician based on his clinical experience.

Artichoke leaf has antioxidant properties and restores healthy growth to liver cells.

Bupleurum may promote normal cell growth, immune function and is a staple of Chinese liver formulas. Dandelion Root may serve as a natural down-regulator of inflammatory chemicals in the body. NAC supports liver Glutathionestores (antioxidant, detoxifier, heavy metal chelator). Schisandra protects liver cells from toxins and may help to regenerate damaged cells. Milk thistle’s antioxidant Silymarin improves liver function tests and protects liver cells against oxidative damage. It also protects liver cells by blocking and removing toxins from the liver. Silymarin aids in regenerating injured liver cells and blocks fibrosis.

OTHER IMPORTANT ISSUES: Samuel Verghese, M.D. (AM), Ph.D., BCIA-EEG, DAAPM, holds a degree in Alternative Medicine and specializes in Nutritional, Ayurvedic and other Alternative Health Solutions. He is certified as a BCIA-EEG Associate Fellow.

AMOUNT TO USE: Three or more capsules a day, preferably with meals.

COMPLEMENTARY PRODUCTS: Antioxidants (supports liver detoxification), Alpha Lipoic Acid, EGCg Green Tea Extract, Astragalus, medicinal mushrooms (shiitake, reishi), SAM-e (may improve bile flow and promotes methylation to detoxify chemicals), TMG, lecithin, thymus glandular extract, Cordyceps.

AVOID: acetaminophen, alcohol, iron supplements (also red meat, fortified flour)

CAUTIONS: This formula should not be used by pregnant women, nursing mothers children or those with liver problems unless recommended under the supervision of a healthcare professional. Please notify your physician about your supplement use if you are using any drugs! Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

REFERENCES:

1. Salmi HA, Sarna S. Effect of silymarin on chemical, functional and morphological alterations of the liver. A double-blind controlled study. Scand J Gastroenterol 1982;17:517–21.
2. Feher J, Deak G, Muzes G, et al. Liver-protective action of silymarin therapy in chronic alcoholic liver diseases. Orv Hetil 1989;130:2723–7 [in Hungarian].
3. Muzes G, Deak G, Lang I, et al. Effect of silymarin (Legalon) therapy on the antioxidant defense mechanism and lipid peroxidation in alcoholic liver disease (double blind protocol.) Orv Hetil 1990:131:863–6 [in Hungarian].
4. Velussi M, Cernigoi AM, De Monte A, et al. Long-term (12 months) treatment with an anti-oxidant drug (silymarin) is effective on hyperinsulinemia, exogenous insulin need and malondialdehyde levels in cirrhotic diabetic patients. J Hepatol 1997;26:871–9.
5. Lieber CS. Nutrition in liver disorders. In: Shils ME, Olson JA, Shike M, Ross AC (eds). Modern Nutrition in Health and Disease, 9th ed. Baltimore, MD: Williams and Wilkins, 1999, 1179–80.
6. Rodriguez-Moreno F, Gonzalez-Reimers E, Santolaria-Fernandez F, et al. Zinc, copper, manganese, and iron in chronic alcoholic liver disease. Alcohol 1997;14:39–44.
7. Gibbs K, Walshe JM. Studies with radioactive copper (64 Cu and 67 Cu); the incorporation of radioactive copper into caeruloplasmin in Wilson’s disease and in primary biliary cirrhosis. Clin Sci 1971;41:189–202.
8. Lieber CS. Nutrition in liver disorders. In: Shils ME, Olson JA, Shike M, Ross AC (eds). Modern Nutrition in Health and Disease, 9th ed. Baltimore, MD: Williams and Wilkins, 1999:1179–80.
9. Halsted CH. Alcohol: medical and nutritional effects. In Ziegler EE, Filer LJ (eds). Present Knowledge in Nutrition, 7th ed. ILSI Press, Washington, DC, 1996, 553.
10. Blum AL, Doelle W, Kortum K, et al. Treatment of acute viral hepatitis with (+)-cyanidanol-3. Lancet 1977;2:1153–5.
11. Suzuki H, Yamamoto S, Hirayama C, et al. Cianidanol therapy for HBs-antigen-positive chronic hepatitis: a multicentre, double-blind study. Liver 1986;6:35–44.
12. Tang W, Eisenbrand G. Chinese Drugs of Plant Origin. Berlin: Springer Verlag, 1992. (Astragalus)
13. Hobbs, C. Medicinal Mushrooms. Santa Cruz, CA: Botanica Press, 1995, 96–107.
14. Harada T, Kanetaka T, Suzuki H, Suzuki K. Therapeutic effect of LEM (extract of cultured Lentinus edodes mycelia) against HBeAg-positive chronic hepatitis B. Gastroenterol Int 1988;1(suppl 1):abstract 719. 15. Kelly GS. Clinical applications of N-acetylcysteine. Altern Med Rev. Apr1998;3(2):114-27.
16. Montanini S, et al. Use of acetylcysteine as the life-saving antidote in Amanita phalloides (death cap) poisoning. Case report on 11 patients. Arzneimittelforschung. Dec1999;49(12):1044-7.
17. Buckley NA, et al. Oral or intravenous N-acetylcysteine: which is the treatment of choice for acetaminophen (paracetamol) poisoning? J Toxicol Clin Toxicol. 1999;37(6):759-67. 18. Girardi G, Elias MM. Effectiveness of N-acetylcysteine in protecting against mercuric chloride-induced nephrotoxicity. Toxicology. Apr1991;67(2):155-64.
19. Berkson MB. Alpha-Lipoic Acid (Thioctic Acid): My Experience With This Outstanding Therapeutic Agent. Journal of Orthomolecular Medicine. 1998;13(1):44-48.
20. Breithaupt-Grogler K, et al. Dose-proportionality of oral thioctic acid--coincidence of assessments via Pooled plasma and individual data. Eur J Pharm Sci. Apr1999;8(1):57-65.
21. Gebhardt R. Antioxidative and Protective Properties of Extracts from Leaves of the Artichoke (Cynara scolymus L.) Against Hydroperoxide-induced Oxidative Stress in Cultured Rat Hepatocytes. Toxicol Appl Pharmacol. Jun1997;144(2):279-86.
22. Adzet T, et al. Hepatoprotective Activity of Polyphenolic Compounds From Cynara scolymus Against CCl4 Toxicity in Isolated Rat Hepatocytes. J Nat Prod. Jul1987;50(4):612-17.
23. Gebhardt R. Antioxidative and protective properties of extracts from leaves of the artichoke (Cynara scolymus L.) against hydroperoxide-induced oxidative stress in cultured rat hepatocytes. Toxicol Appl Pharmacol. Jun1997;144(2):279-86.
24. Khadzhai I, et al. Effect of Artichoke Extracts on the Liver. Farmakol Toksikol. Nov1971;34(6):685-87.
25. Newall CA, et al. Herbal Medicine: A Guide for Health-Care Professionals. Cambridge: Pharmaceutical Press; 1996:36-37.
27. Newall CA, et al. Herbal Medicines: A Guide for Health Care Professionals. London: The Pharmaceutical Press;1996:96-97.
28. Bradley PR, ed. British Herbal Compendium. Vol.1. Bournemouth: British Herbal Medicine Association;1992:73-74.
29. Newall CA, et al. Herbal Medicines: A Guide for Health Care Professionals. London: The Pharmaceutical Press;1996:96-97.



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Maintaining Healthy Veins
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Date: July 25, 2005 09:36 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Maintaining Healthy Veins

More than 40 million Americans have varicose veins, a term in Latin meaning “twisted and wollen blood vessel.” Although the condition is rarely disabling, it is disfiguring, causing discomfort and embarrassment to those afflicted.

many cases, genetic predisposition and gender determine who will develop varicose veins. A full 75% of Americans with the condition ar e women. At risk some women who may experience the beginning of this condition during pregnancy as the enlarging womb presses on the veins in the abdomen, increasing the pressure in the veins of the legs.

Age is another factor as the skin becomes less elastic, lessening vein support. Some individuals are genetically edisposed to a malfunction of the one-way valves that may cause a back low of blood to Pool in super ficial veins, stretching and swelling them.

some health care professionals believe that our Western diet, high in refined carbohydrates and fat and low in fiber, may cause straining during bowel movement leading to hemorrhoids (anal varicose veins) and increase pressure on the leg veins. Our Western diet also eads to obesity and cardiovascular conditions such as plaque deposits in the arteries, abnormal clotting and platelet aggregation, cardiac dysfunction or failure, all leading to a weakened venous system that could increase the chance of developing varicose veins and edema (swelling in the legs). Those who ar e predisposed to varicose veins and who stand for long periods of time, especially on hard floors, may develop them more quickly.

If you are at risk of developing this condition as you age, emphasizing a diet high in fiber, legumes and grains, fresh fruits and vegetables will improve your chances of maintaining good vein health. Other nutritional supplements that may be beneficial are horse chestnut seeds, Centella Asiatica, Milk Thistle, Butcher’s Broom and bioflavonoids.

Horse chestnut seeds have a long historical use in the treatment of varicose veins and hemorrhoids. One active ingredient that has been researched is a saponin mixture called Aescin. In a recent study, Aescin was as effective as compression stockings in reducing leg swelling in patients with chronic venous insufficiency.

Centella Asiatica is a common edible herb also known as Gotu Kola in India. When grown in Madagascar, it has a higher content of a compound called triterpenic fraction (TTFCA) than the same herb has when grown in other parts of the world. This compound has been used for many years in the treatment of venous hypertension. In a study conducted in 1989, 120mg dosage was safely used in patients with poor venous blood flow and it improved the condition after one or two months.

Often, inflammation is a component of varicose veins. Milk Thistle, another herb commonly used for the treatment of liver disorders, was also found to reduce inflammation and edema in a recent Spanish study.

A bushy ever green perennial found throughout much of the Western world is Butcher’s Broom. Its saponin glycosides ar e anti-inflammatory and helped contract blood vessels, especially veins thus making it an important component of any natural for mulation used to improve venous conditions.

Certain bioflavonoids, such as quer cetin and rutin, have also been shown to be useful in the natural tr eatment of varicose veins as a strengthener of capillary and vein walls.

There are other nutritional supplements including vitamins and minerals that may help maintain vein health as we age. They are listed in my new book “A Doctor’s Guide to Natural Medicine.” To improve vein health and to decrease your chance of developing varicose veins: do not stand for long periods of time especially on hard sur faces such as concrete. If you can’t avoid this, make sure your shoes are well cushioned. If you are sitting for long periods of time either working or traveling, take walking breaks. Stop crossing your legs and exercise regularly to incorporates rhythmical contraction of the leg muscles. Rest with your legs elevated when taking a break. W earing good support hose and avoiding tight knee-highs will promote good blood flow.

These things can be very important if you ar e genetically pr edisposed to varicose veins. Starting nutrients early may help diminish or delay venous problems.

Micromedex, Inc. Volume 96, 1974-1998. Diehmetal. Microcirculation Laboratory, Cardiovascular Clinic, Chieti, Italy.

Efficacy of Centellase in the Treatment of Venous Hypertension Evaluated by a Combined Micro circulatory Model. G. Belcaroetal. Current Therapeutic Research, Vol. 46, No. 6, Dec. 1989.

Effect of Silymarin on Different Acute Inflammation Models and on Leukocyte Migration. R. de la Puertaetal, J. Pharm. Parmacol. 1996, 48: 968-970 Merck Sciential Review, no. 10, 1995-04-30, pp. 2



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Nothing to Sneeze At
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Date: June 18, 2005 08:41 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Nothing to Sneeze At

Nothing to Sneeze At by Carole Poole Energy Times, August 14, 2004

To many, nothing is more annoying than a persistent allergy. Runny nose, itchy eyes, hives, sneezing, coughing...Frequently, allergies seem to represent suffering with no end.

When you are sensitive to something in your environment, often your only hope for relief appears to be to flee to an elsewhere that eludes the problematic, trouble-making allergen.

Complementary measures are available that can lower your risk of allergic reactions. Heading off allergic reactions before they strike can help you enter a comfort zone that leaves nothing to sneeze at.

Limit Your Antibiotics

While people have always suffered allergies, today, many experts agree, allergies are on the rise. One possible explanation: antibiotics. For instance, research at the Henry Ford Hospital in Detroit demonstrates that kids who get antibiotics within six months of being born run an increased risk of being allergic to dust mites, ragweed, grass and animals. At the same time, if two or more cats or dogs live with them, they reduce their chances of allergies (Eur Respir Soc ann conf, 2003).

" I'm not suggesting children shouldn't receive antibiotics. But I believe we need to be more prudent in prescribing them for children at such an early age," Christine Cole Johnson, PhD, says. "In the past, many of them were prescribed unnecessarily, especially for viral infections like colds and the flu when they would have no effect anyway."

Dr. Cole's investigators found that by age 7, kids who got one or more rounds of antibiotics were:

  • • 1.5 times more likely to develop allergies
  • • 2.5 times more likely to develop asthma
  • • Twice as likely to get allergies if their mothers had allergies

    When antibiotics are necessary, they are crucial to quelling bacterial infections. However, if you or your children suffer colds or flus, diseases caused by viruses, antibiotics have no effect on your illness but could increase your chance of developing allergies.

    " Over the past four decades there has been an explosive increase in allergy and asthma in westernized countries, which correlates with widespread use of antibiotics and alterations in gastrointestinal (GI) microflora," says Mairi Noverr, a researcher on a study linking allergies to antibiotic use (104th Gen Meet Amer Soc Microbiol, 2004). "We propose that the link between antibiotic use and dysregulated pulmonary immunity is through antibiotic-induced long-term alterations in the bacterial and fungal GI microflora." While a lot of research needs to be done, it may help to fortify the probiotic, or good, microbes in your intestines with probiotic supplements. One study has shown that giving probiotics to pregnant women helped their children avoid allergic eczema, a skin condition (Lancet 2001; 357:1076-9).

    Green Tea Relief

    Research has demonstrated that various types of tea can produce a range of health benefits. Tea drinkers can add allergy relief to that list.

    Research in Japan demonstrates that for the allergy-oppressed, green tea may help them have nothing to sneeze at. In laboratory tests, scientist found that green tea contains a substance that blocks one of the immune cell receptors which is often a part of the allergic response. The substance, methylated epigallocatechin gallate (EGCG), is believed to have a similar effect in the real world (J Agr Food Chem 10/9/02).

    " Green tea appears to be a promising source for effective anti-allergenic agents," notes Hirofumi Tachibana, PhD, the study's chief investigator and an associate professor at Kyushu University in Fukuoka. "If you have allergies, you should consider drinking it." Traditionally, many people have consumed tea as part of their effort to suppress sneezes, coughs and itchy eyes caused by allergies. This experiment supports the evidence that green tea, in particular, has a reliable effect.

    According to Dr. Tachibana, green tea's anti-allergenic benefits have not been completely established, but tea apparently has the potential to be effective against allergens like dust, chemicals, pet dander and pollen.

    Tea Antioxidant

    EGCG has also been shown to be a very active antioxidant, helping to quell the destructive effects of the caustic molecules known as free radicals. Green tea is richer in EGCG than black tea or oolong tea (a type that falls between black and green).

    Although other research has demonstrated that EGCG offsets allergic responses in lab animals fed this substance, scientists don't completely understand why it works for allergies. Researchers theorize that EGCG restricts the production of histamine and immunoglobulin E (IgE), two substances secreted in the body as part of the chain of chemical reactions that lead to an allergic reaction, says Dr. Tachibana.

    This study shows, for the first time, that a methylated form of EGCG can block the IgE receptor, which is a key receptor involved in an allergic response. The effect was demonstrated using human basophils, which are blood cells that release histamine. As of now, nobody knows how much green tea you need to guzzle to have the best protection against allergies and, of the several varieties available, nobody knows which green tea is best.

    Outside of the US, green tea is the second most popular beverage in the world, right behind water. In the US, however, black tea is more popular than green. But the allergy sensitive should think and drink green.

    Stay Away from Diesels

    Those who are allergic to ragweed or pet dander usually know they should avoid the source of their allergies. But now scientists have found that, for many allergy sufferers, diesel exhaust can also worsen sneezes and wheezes.

    Scientists at two southern California schools have shown that about half of us have inherited a sensitivity to diesel pollution that can make our allergies significantly worse (Lancet 1/10/04). "[T]his study suggests a direct way that pollution could be triggering allergies and asthma in a large number of susceptible individuals...," says Frank D. Gilliland, MD, PhD, the study's lead author. Diesel exhaust particles are thought to act as destructive free radicals in the lungs, forming caustic molecules that damage lung tissue. This irritation can cause your immune system to create larger amounts of compounds that make you sneeze and wheeze more.

    The Antioxidant Advantage

    Antioxidants, scientists believe, can help defuse this damage and ease the body's allergic responses. The California scientists looked at two antioxidant enzymes the body makes to protect the lungs called glutathione S-transferase M1 (GSTM1) and glutathione S-transferase P1 (GSTP1). Only about five of ten people's immune systems can make all the effective forms of these enzymes. The rest of us lack this protection to some degree, and the immune system in about one in five people can't make any effective form of these enzymes.

    The research team found that people allergic to ragweed who lacked these antioxidant enzymes suffered more when they took in both ragweed pollen and particles from diesel pollution.

    Breathe Easier With C

    This research may help explain why many health practitioners recommend vitamin C, a potent antioxidant, to allergy sufferers. Vitamin C "prevents the secretion of histamine by the white blood cells, increases the detoxification of histamine and lowers the blood-histamine levels," says Sylvia Goldfarb, PhD, author of Allergy Relief (Avery/Penguin).

    Scientists continue to study the allergy conundrum. Meanwhile, sip a cup of green tea and shut the window before the next truck comes by.



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    Inflama Rest - Natural COX-2 Inhibitor for Joint Comfort
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    Date: June 02, 2005 12:37 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Inflama Rest - Natural COX-2 Inhibitor for Joint Comfort

    It happens. You reach for something and feel a sudden discomfort. Your joints and muscles may feel tender from overuse. Inside, your cellular systems are out of alignment, resulting in lessened mobility. Source Naturals understands how difficult joint discomfort can be to live with. We are deeply committed to developing well-researched formulas that address the root cause of joint distress. Our Bio-Aligned Formulas™ bring alignment to multiple interdependent body systems. Only this type of indepth formulation can provide the long-term relief you are looking for. Regain your comfort with Source Naturals INFLAMA-REST. Unlike many products that contain just a few ingredients to offer temporary relief, INFLAMA-REST is a Bio-Aligned Formula™, scientifically designed to address aches. INFLAMA-REST goes deep to the underlying cause of joint discomfort. These systems include: inhibition of pathways involved in joint discomfort, joint and muscle function, DNA protection and antioxidant defense.

    Addressing Joint Comfort on a Deep Cellular Level

    Discomfort can come from many places. From your head to your toes there are many tissues that can become uncomfortable from everyday use. Joint discomfort starts when stress, such as tissue damage, causes an imbalance of the biochemical pathways on a deep cellular level. The body has its own “innate intelligence” encompassing more than just the thoughts in the brain. It consists of ongoing and complex chemical reactions regulated by a wide variety of enzymes and chemical messengers. These reactions can sometimes get out of balance – but you can control and inhibit key body chemicals that would otherwise lead to cellular irritation. For example, certain types of prostaglandins that regulate normal physiological functions such as blood flow, are maintained at low levels in all our cells under everyday conditions. In response to stress, a message is sent to the outer membranes of certain cells to convert their fatty acids into arachidonic acid, the raw material for prostaglandins. This stress also directs cells to produce Cyclooxygenase enzyme- 2 or COX-2. This enzyme converts arachidonic acid into Prostaglandin E2, a particular type of prostaglandin specifically responsible for irritation on a cellular level. The result: joint discomfort. But that doesn’t have to happen. By supporting inhibition of the culprit COX-2, you can decrease Prostaglandin E2 production to bring your joint tissues back into a healthy and comfortable balance.

    Support COX-2 Inhibition

    INFLAMA-REST includes herbs that support inhibition of COX-2 in a variety of pathways. Ginger, turmeric and green tea all support direct COX-2 inhibition. But there are other places in our biochemical communication system where COX-2 production can be inhibited. Two additional factors that lead to COX-2 production are nitric oxide and the enzyme that produces it, nitric oxide synthase (iNOS). Nitric oxide is a free radical associated with cell growth and regeneration, blood vessel elasticity and COX-2 enzyme production. Resveratrol, rosemary and turmeric support iNOS inhibition, thus inhibiting your body’s over-production of nitric oxide and the COX-2 enzyme. A related irritation factor is also one of the latest scientific discoveries in cellular health - Nuclear Factor kappa-B (NF-kappa-B). NF-kappa-B works at the DNA level – at the blueprints of cells. When activated, this factor controls the genes that regulate cell growth, differentiation and regeneration. And blocking this factor is also associated with inhibition of both COX-2 and iNOS enzymes. Stinging nettle, milk thistle and Chinese Skullcap all block unhealthy NF-kappa-B activation in your body and thereby help support COX-2 inhibition.

    Cytokine Inhibition

    Compounds called cytokines, or interleukins, can also stimulate biochemical pathways leading to joint discomfort. Cytokines are chemical messengers produced by the immune system to regulate defensive activity when they are stimulated. For example, cytokines are released by macrophages in response to stimuli such as tissue damage. This results in rapid escalation and amplification of cell number and response. Constant stress can shift this system out of balance, resulting in tissue discomfort. Bringing these compounds back into balance can preserve your short-term comfort and longterm health. INFLAMA-REST contains curcumin from the spice turmeric. Curcumin assists the body’s inhibition of cytokine activity to support reduced cellular irritation. And Bioperine®, which is derived from black peppercorns, is added to assist curcumin assimilation.

    Stress Response: Joints and Muscle Support

    Inhibition of chemical messengers involved in joint discomfort is just part of a Bio-Aligned strategy for relieving discomfort. Research has shown that emotional stress, particularly long-term, can directly affect the body and set in motion mechanisms that cause physical discomfort. Ashwaganda and Chinese Skullcap (S. baicalensis) are herbs that help modulate the body’s response to stress and may help ease aches and discomfort. Boswellia, ginger, quercetin, milk thistle, feverfew, Oregon grape root and bromelain (an enzyme found in pineapples) provide additional soothing relief to your cells and tissues. Essential nutrients are also vital to maintaining your joint comfort. The tocotrienol forms of vitamin E, along with selenium, protect cell membranes from lipid-based free radicals. Magnesium aids energy metabolism in muscles and can reduce tenderness as well as muscle spasms. Zinc is essential for normal cellular repair mechanisms such as wound healing and is important for the growth and maintenance of connective tissue. And manganese works to protect cells from oxidation and to build healthy connective tissue as well, an essential component of healthy joints and muscles.

    Protecting Your DNA

    To reduce cellular irritation, you need to protect the DNA in your cells. DNA is the blueprint for all of the molecules in the body. If your DNA is altered or damaged, then needed molecules may not be produced, leading to short-term and eventually long-term damage. Curcumin, from turmeric, has been shown in in-vitro studies to protect DNA against strand breakage. Quercetin has also been shown to directly protect DNA against strand breakage and base oxidation from free radicals and damaging chemicals, according to recent in-vitro research.

    Providing Powerful Antioxidant Cellular Protection

    Antioxidants are selfless bodyguards of your cells. They donate their own electrons to stabilize free radicals in your body. Thus, antioxidants absorb the damage that would have been done to your tissues. Some regulatory chemicals, such as Nitric oxide, are powerful free radicals and oxidants. Oxidants also activate NF-kappa-B. Tissues, lipids, proteins and DNA are extremely sensitive to oxidation. Quercetin, milk thistle, turmeric, ginger, rosemary, vitamin E and resveratrol are all antioxidants that help modulate the activity of these compounds as well as protect cells and tissues from damage. Plus, Superoxide Dismutase (SOD), one of the most important enzyme antioxidants found in your body, has been added in a new cutting-edge form. The vegetarian SOD used in INFLAMA-REST is attached to Gliadin, a wheat protein, that has demonstrated significantly better absorption than SOD alone.

    Six Lifestyle Strategies for Fewer Aches


    1. Try Yoga or Tai Chi. Low-impact exercise based on slow fluid movements can improve mobility and flexibility as well as greatly reduce stress.
    2. Get in the Pool. Exercising while in the Pool reduces strain on the joints in addition to strengthening muscles.
    3. Maintain a healthy weight. Excess weight adds pressure to joints and connective tissues.
    4. Eat omega-3s. Omega-3 fatty acids found in salmon, flax seeds, or in supplement form support healthy joints and tissues.
    5. Stay hydrated. Water is the basis of lubrication in connective tissues such as joints and skin and also supports detoxification.
    6. Supplement with glucosamine, chondroitin, MSM and hyaluronic acid. These supplements can help maintain healthy connective tissues. Source Naturals is pleased to partner with your local health food store to provide INFLAMA-REST as a comprehensive Bio- Aligned Formula for relieving joint discomfort by protecting, nourishing and soothing irritated cells. Make INFLAMA-REST part of your health plan to live without joint discomfort.

  • INFLAMA-REST is a Bio-Aligned Formula™ Multi-System Support for Joint Comfort

    Inhibition of COX-2: Turmeric, Ginger, Chinese Skullcap, Green Tea, Resveratrol, Boswellia, Silymarin, White Willow Inhibition of Cytokine Turmeric, Stinging Nettle, Feverfew Inhibition of Rosemary, Green Tea, Resveratrol, Turmeric, Quercetin, Chinese Skullcap NF-kappa-B Activation Silymarin, Chinese Skullcap, Stinging Nettle, Rosemary, Resveratrol Stress Response: Ashwaganda, Magnesium, Chinese Skullcap, Oregon Grape, Feverfew, White Willow DNA Protection Turmeric, Quercetin, Rosemary Antioxidant Defense Silymarin, SOD Gliadin, Turmeric, Rosemary, Tocotrienols, Resveratrol, Ginger, Selenium, Manganese, Zinc Prostaglandin & Leukotrine Synthesis Joint & Muscle Support Inhibition of Nitric Oxide Synthesis Production



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    HEART RESPONSE - Comprehensive Support for a Healthy Heart!
    TopPreviousNext

    Date: June 02, 2005 11:51 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: HEART RESPONSE - Comprehensive Support for a Healthy Heart!

    Heart Response 60ct

    Today’s modern lifestyle, filled with stress, pollution, overprocessed and fatty foods, and lack of exercise, places great strains on the cardiovascular system. Source Naturals HEART RESPONSE is a broad-range formula that supports cardiovascular health, especially heart muscle contraction, healthy circulation and the generation of cellular energy.

    HEART RESPONSE features clinical potencies of the renowned heart botanical, hawthorn, and significant amounts of the energy nutrients, coenzyme Q10 and carnitine, along with additional nutrients and herbs. Each daily use supplies 600 mg of hawthorn, the same amount used in recent research.

    Supports Heart Health

    HEART RESPONSE was formulated to include key nutrients and herbs known to support the cardiovascular system.

    Hawthorn: Hawthorn, a rich source of flavonoids and procyanidins, has been used traditionally all over the world as a strengthening circulatory and heart tonic.

    Modern research has documented that hawthorn increases coronary blood flow and strengthens the contraction of heart muscle. Hawthorn is also an antioxidant, which scavenges and neutralizes destructive free radicals. It is only when cholesterol is oxidized that it impacts the integrity of arteries.

    Coenzyme Q10: HEART RESPONSE supplies 60 mg daily of CoQ10, a key enzyme in the Electron Transport Chain, the pathway that generates 90% of the ATP “energy currency” needed by the body. Heart muscle requires huge amounts of energy to perform efficiently—it beats more than 100,000 times each day, pumping more than 1,000 gallons of blood through the body. The heart utilizes ATP as an energy source for muscular contraction. CoQ10 also is a fat-soluble antioxidant.

    L-Carnitine: Carnitine is an amino acid-derived substance that supports heart muscle metabolism. Carnitine is needed to carry long chain fatty acids into the cell mitochondria, where they undergo oxidation to generate energy. The heart utilizes fatty acids as a preferred energy source for its metabolism.

    HEART RESPONSE delivers 300 mg per day of carntine. Taurine and Magnesium: Magnesium and taurine work closely together in the body to help maintain the normal electrical rhythm of the heart. Taurine comprises more than 50% of the free amino acid Pool in our hearts, and has many electrophysiological effects on cardiac muscle cells. Alterations in magnesium levels can have profound effects on the heart. Magnesium is involved in autonomic control of the heart through several mechanisms. Bromelain: Bromelain is an enzyme mixture prepared from pineapple stems. Pineapple has been used for its health benefits for more than 500 years.

    Grape Seed Extract: Grape seed is a source of procyanidins. These plant constituents are strong antioxidants that inhibit lipid peroxidation and scavenge free radicals. In vitro studies have demonstrated that procyanidins support the integrity of connective tissue. Garlic: The use of garlic for its health benefits predates written history. Garlic’s volatile oil includes sulfur-containing compounds such as allicin, which are considered to be important biological constituents.

    Selenium: Selenium is an essential trace mineral that is necessary for the activity of the important antioxidant glutathione. Antioxidants are crucial for protecting cholesterol from oxidation, which in turn helps to maintain healthy blood vessels. B-Vitamins: Preventing an undesirable buildup of homocysteine levels may help support the integrity of arteries. Vitamins B-6, B-12 and folic acid are critical to the regulation of homocysteine levels.

    You can count on Source Naturals’ expert formulators to bring you a product based on the most up-to-date nutritional research. HEART RESPONSE combines traditional botanicals and cutting-edge nutrients, scientifically formulated to deal with many aspects of cardiovascular health. It is available in bottles of 30, 60 and 90 tablets.

    References
    Heinicke, R.M. et al. 1972. Effect of bromelain (ananase) … Experientia. 28(7):844-5. Karpati, G. et al. 1975. The syndrome of carnitine deficiency. Neurology. 25:16-24. Schmidt, U. et al. 1994. Efficacy of the Hawthorn (Cratageus) preparation L1 132 … Phytomedicine. 1:17-24. Upton, R. ed. Hawthorn Leaf with Flower – Cratageus spp. Santa Cruz: American Herbal Pharmacopoeia, 1999.



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    Garlic Consumption and Cancer Prevention...
    TopPreviousNext

    Date: May 12, 2005 12:34 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Garlic Consumption and Cancer Prevention...

    Garlic Consumption and Cancer Prevention: Meta-Analyses of Colorectal and Stomach Cancers

    Author:
    Fleischauer AT, Poole C, Arab L

    Source:
    Am J Clin Nutr. 2000;72:1047-1052.

    Abstract:
    BACKGROUND: Animal and in vitro studies have provided evidence of an anticarcinogenic effect of active ingredients in garlic.
    OBJECTIVE: The objective was to conduct meta-analyses of the epidemiologic literature on the association between garlic consumption and risk of stomach, colon, head and neck, lung, breast, and prostate cancers.


    DESIGN: Meta-analyses were conducted for all cancers mutually and separately for colorectal and stomach cancers in relation to consumption of exclusively raw garlic, cooked garlic, or both (RC garlic). Eighteen studies reported a relative risk estimate for RC garlic consumption and cancer risk.


    RESULTS: In the meta-analyses of colorectal and stomach cancer, the reference categories ranged from no consumption to consumption of 3.5 g/wk, whereas the highest categories ranged from any consumption to >28.8 g/wk. The average difference between the highest and lowest categories was 16 g/wk. The random-effects relative risk (RR) estimate of colorectal cancer and RC garlic consumption, excluding garlic supplements, was 0.69 (95% CI: 0.55, 0.89). For stomach cancer, the random effects RR estimate was 0.53 (95% CI: 0.31, 0.92). The heterogeneity among studies for the latter outcome (P = 0.0002) indicates the questionableness of the generalizability of this summary estimate. An indication of publication bias for all cancers combined is evident from a funnel plot of RC garlic consumption and cancer risk and from the results of the Begg and Mazumdar test (P = 0.049).


    CONCLUSIONS: High intake of RC garlic may be associated with a protective effect against stomach and colorectal cancers. Heterogeneity of effect estimates, differences in dose estimation, publication bias, and possible alternative hypotheses (eg, confounding by total vegetable consumption) preclude sole reliance on summary effect estimates.
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    Garlic as a Lipid Lowering Agent-A Meta-Analysis
    TopPreviousNext

    Date: May 12, 2005 12:20 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Garlic as a Lipid Lowering Agent-A Meta-Analysis

    Garlic as a Lipid Lowering Agent-A Meta-Analysis

    Author:
    Silagy C, Neil A

    Source:
    Journal of the Royal College of Physicians of London. 1994; 28(1):39-45.

    Abstract:
    Garlic supplements may have an important role to play in the treatment of hypercholesterolaemia. To determine the effect of garlic on serum lipids and lipoproteins relative to placebo and other lipid lowering agents, a systematic review, including meta-analysis, was undertaken of published and unpublished randomized controlled trials of garlic preparations of at least four weeks duration. Studies were identified by a search of MEDLINE and the ALTERNATIVE MEDICINE electronic databases, from references listed in primary and review articles, and through direct contact with garlic manufacturers. Sixteen trials, with data from 952 subjects, were included in the analyses. Many of the trials had methodological shortcomings. The Pooled mean difference in the absolute change from baseline to final measurement in mmol/l) of total serum cholesterol, triglycerides, and high-density lipoprotein (HDL)-cholesterol was compared between subjects treated with garlic therapy against those treated with placebo or other agents. The mean difference in reduction of total cholesterol between garlic-treated subjects and those receiving placebo (or avoiding garlic in their diet) was -0.77 mmol/l (95% CI: -0.65, -0.89 mmol/l). These changes represent a 12% reduction with garlic therapy beyond the final levels achieved with placebo alone. The reduction was evident after one month of therapy and persisted for at least six months. In the dried garlic powders, in which the allicin content is standardized, there was no significant difference in the size of the reduction across the dose range of 600-900 mg daily. Dried garlic powder preparations also significantly lowered serum triglyceride by 0.31 mmol/l compared to placebo (95% CI: -0.14, -0.49). HDL-cholesterol was non-significantly lowered by 0.04 mmol/l (95% CI: -0.11, 0.03 mmol/l). Side effects from garlic therapy, other than odor, were rare. In conclusion, use of garlic therapy, either as dried garlic preparations (in doses as low as 600 mg per day) or as fresh, high allicin yielding garlic (10-20 g per day) appears significantly to reduce total serum cholesterol over a 1-3 month period. However, more rigorously designed and analyzed trials are needed. --
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