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Search Term: " ehanol "
What is DMAE and Why is it Important?   
Date:
October 10, 2022 04:25 PM
DMAE (Dimethylaminoethanol) is an amino alcohol that is normally found in minute quantities in the brain. It is generally regarded as a precursor to the essential nutrient choline, which is needed for the brain to produce acetylcholine, a neurotransmitter involved in nerve signal transmission and healthy brain function.* So what does that mean for you and your health? Let's take a closer look. DMAE has been shown to have a positive effect on cognitive function and memory, which is why it's often referred to as "the memory vitamin." In one study, supplemented with DMAE showed significantly improved verbal skills and memory recall compared to those who did not take the supplement. Supplemental DMAE has also been shown to improve focus and reduce mental fatigue. In addition to its cognitive benefits, DMAE has also been shown to have anti-inflammatory and antioxidant effects. Inflammation is linked to a number of chronic diseases, so reducing inflammation can lead to better overall health. The antioxidant effects of DMAE may help protect cells from damage caused by free radicals. In Summary: DMAE is a nutrient that is normally found in minute quantities in the brain. It plays a crucial role in cognitive function and memory recall, and has also been shown to have anti-inflammatory and antioxidant effects. If you're looking for a way to improve your cognitive function, memory, focus, or overall health, consider adding DMAE to your diet. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6497) Antimicrobial properties of red ginseng make it a great naturalcure for acne 
Date:
May 06, 2019 03:42 PM
Phytotherapy Research recently published new South Korean research indicating the effectiveness of red ginseng extract against acne symptoms. They studied red ginseng ethanol extract and found that it exhibits comparable anti-microbial properties to those of the most common antibiotic acne medications. Red ginseng has been prized throughout Asia for its medicinal properties for many years. It also has other effects that can help fight acne, including boosting the immune system and improving sleep quality and endocrine balance throughout the body. Key Takeaways:
"They found that red ginseng ethanol extract exhibited similar, if not even better, antimicrobial activity against Propionibacterium acnes compared to benzoyl peroxide or azelaic acid." Read more: https://www.naturalnews.com/2019-03-21-red-ginseng-a-great-natural-cure-for-acne.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6267) Oat extract can protect against alcohol-induced liver damage
Date:
May 02, 2019 02:59 PM
Eating oats may prevent liver damage caused by drinking, according to research published in the journal Nutrition Research. Indian researchers tested the effects of oat extract on mice with alcohol-induced liver damage. First, they pretreated mice with phenolic-enriched ethyl acetate fraction of oats at two levels every day for 12 days. Next, they induced liver damage in the same mice with doses of 50 percent ethanol every 12 hours. Their results showed that pretreatment with oat extract at higher dosages decreased the levels of liver injury. Key Takeaways:
"Research has found an association between consumption of oats and lower risk of cardiovascular disease, diabetes, and gastrointestinal disorders." Read more: https://www.naturalnews.com/2019-03-13-oat-extract-can-protect-against-alcohol-induced-liver-damage.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6244) A species of hawthorn has been found to control abnormally highblood sugar levels
Date:
May 02, 2019 02:45 PM
A team of researchers from the Middle East have found that a species of hawthorn, Crete hawthorn, has the ability to lower elevated levels of glucose in the blood. They have published their findings in the journal BMC Complementary and Alternative Medicine. Along with its effects on blood glucose, called its anti-hyperglycemic property, it also has hyperlipidemic properties, that is, the ability to protect the body against high levels of fat such as cholesterol in the blood. They carried out the study using mice that were induced with hyperglycemia through feeding them alloxan. The mice were then divided into two groups, one group receiving Crete hawthorn extracts and the other given a chemical for control. They also used another animal model to understand its hyperlipidemic properties and to investigate whether the plant had antioxidant and antimicrobial properties. The results of the findings were that Crete hawthorn had important antioxidant properties due to its containing phenols and flavonoids. They also found that it had antimicrobial properties because it acted against bacteria such as E. Coli and Staphylococcus aureus, among others. Key Takeaways:
"The mice were then divided into groups, with some receiving an ethanol extract from Crete hawthorn leaves while others were given glibenclamide for positive control." Read more: https://www.naturalnews.com/2019-03-12-hawthorn-controls-high-blood-sugar-levels.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6243) Red ginseng is a natural cure for acne
Date:
April 30, 2019 04:16 PM
According to a South Korean study published in Phytotherapy Research, red ginseng can be an effective treatment for acne in place of traditional medications with potential negative side effects. In fact, red ginseng performed as good or better than benzoyl peroxide in terms of its effectiveness against fighting acne. Specifically, redness symptoms were significantly reduced with the use of red ginseng. The study concluded that the participants acne improved because of panaxynol and panaxydol, the active ingredients in red ginseng. Key Takeaways:
"They recruited 20 participants and treated them with cream that contains 3 milligrams per gram (mg/g) of red ginseng ethanol extract for four weeks." Read more: https://www.naturalnews.com/2019-03-12-red-ginseng-is-a-natural-cure-for-acne.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6227) Eat more artichokes! Their leaves contain powerful compounds thatprotect you from diabetes
Date:
April 04, 2019 09:27 AM
Diabetes has the harmful potential of damaging the liver, kidneys, and pancreas. Fortunately, research is now showing that the consumption of artichoke leaves can protect your organs from this oncoming threat. This was concluded after a study was performed on rats, giving them a certain amount of alloxan each day which mimicked the effects of artichoke leaves. Once tissue was extracted from their organs, it showed that it was much less damaged than those who were not exposed to the alloxan. Key Takeaways:
"People who are at risk of diabetes and other metabolic disorders would do well to add artichokes (Cynara scolymus) in their diet to lower their chances of getting the disease, according to researchers from the University of Sfax in Tunisia." Read more: https://www.naturalnews.com/2019-02-04-artichoke-leaves-protect-you-from-diabetes.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6119) Noni is great for your colon
Date:
February 08, 2019 08:23 AM
Gut flora is vital to digestive health. An imbalance in this causes many ailments, such as irritable bowel syndrome, poor nutritional uptake, and bloating. Fermented Noni has been shown to promoted growth of several good bacteria in the gut that relieves inflammation of the digestive tract. Noni has also proven effective in helping to relieve inflammation and pain in other parts of the body. Traditionally it has been used to help treat infections and has a positive aspect in lowering cholesterol and may help to prevent damage from stroke events. Key Takeaways:
"You can keep your digestive system healthy with the help of fermented noni (Morinda citrifolia L.)" Read more: https://www.naturalnews.com/2018-12-21-noni-is-great-for-your-colon.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6008) Why the Indian olive is one of the best superfoods of all
Date:
September 02, 2018 05:53 PM
In today's day and age, many people are going through a phase of where they want to eat very healthy and are willing to go to a very far extent to ensure that they stick to a diet. Now, there are things like Indian olive which is considered to be a super food. Of course there is acai and most people know what that is. However, Indian olive is a new one that has been received well by many. Key Takeaways:
"For the study, the researchers looked at the phenolic contents, antimicrobial, and antioxidant activities of the olive plant. They used three crude extracts of the leaf and bark extracts of the olive tree: chloroform, ethanol, and methanol extracts." Read more: https://www.naturalnews.com/2018-08-30-why-the-indian-olive-is-one-of-the-best-superfoods.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5740) Cannabis Oil Extraction
Date:
May 18, 2017 11:44 AM
Within a marijuana plant there is an oil that can be extracted. There are a few ways to extract this oil, but one with butane or hexane could be very unsafe and harmful to the body. Healthier ways to extract this oil include olive oil. However, the oil is perishable so quick use is recommended. A carbon dioxide extraction is possible but needs a lot of equipment and a high quality of thinking. Lastly, a high grade ethanol can be used and is more common for cartridges. Key Takeaways:
"Cannabis oil made with neurotoxic solvents like butane and hexane may leave unsafe residues that compromise immune function and impede healing." Read more: https://www.projectcbd.org/cannabis-oil-extraction
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4640) Supplements That Can Improve Focus
Date:
March 23, 2014 07:57 AM
A focused mind is one that is able to concentrate on a particular issue and think about it, discuss it or deal with it and pay special attention to that subject. This explains why people have different focus abilities as brought about by their varying environments and capabilities. Enhanced minds quickly grasp ideas as opposed to low minded ones. A determined mind therefore understands and interpret facts more readily in an effective way, and this is why it is important for individuals to to be focused at school. However, there are instances where learners have limited focus abilities, but this can be improved by use of focus supplements. The following are the supplements that can be used to boost an individual's focus levels. Supplement that can help improve focus
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3074) Can DMAE Help Memory And Mood?
Date:
December 19, 2013 07:23 AM
Do you ever feel like you are experiencing lapses in memory or you have a low general mood? There is evidence that DMAE might be able to help with both memory and mood. DMAE occurs naturally in the human brain. When we take supplemental amounts of the compound, brain function effects can be seen. DMAE as a Supplement It is thought that the supplement works by increasing the speed of the brain's turnover and synthesis of a neurotransmitter called acetylcholine. This neurotransmitter plays a strong role in maintaining general mental ability. It also works at supporting a stable, healthy memory in older adults. It is also believed that DMAE might work by stopping choline metabolism. This allows the free choline to gather in the blood, go into the brain, and stimulate the cholinergic receptors. A French double-blind study was performed to measure how much of an impact the supplement DMAE has on both mood and vigilance. Four of the subjects were categorized as having anxiety, and four other subjects were the controls. They were each given 1200mg of DMAE over the course of 5 days. These subjects were measured daily for their EEG and convergence of the inter hemispheres of the brain. In the case of the four subjects that were given the supplement, progressive sync of the two brain hemispheres was found. This is correlated with increased neuromotor control, increased verbal memory, improvement in behavioral tasks, as well as better control of anxiety. Another use for DMAE worth mentioning is its affects on learning deficiencies like ADD or hyperkinesia. Many doctors prescribe amphetamines for conditions like this, but DMAE has also proven useful. According to studies, hyperactivity and irritability decrease, and scholastic ability improves from supplementing with DMAE. In addition to improving these conditions there is evidence that DMAE can improve life span, IQ, and motor mechanisms. It is very important to take the correct dosage of DMAE. I would start with taking 200-400mg first, and work your way up from there. Sources:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2929) Green Coffee Bean Extract
Date:
November 22, 2012 10:31 PM
Many studies have been carried out to establish the health benefits of Green coffee bean extract for several years. It was just in 2012 that some group of scientists revealed a particular study that demonstrated Green Coffee Bean Extract‘s effectiveness in contributing to weight loss. Leading this study was Dr Joe Vinson, a scientist from the University of Scranton. On the same note, sixteen over-weight people also participated in the study. They were all given varying doses of the Green Coffee Bean Extract for a period of 22 weeks. These participants lost around 17 pounds when the study ended. They did not report any side effect. Moreover, they were under no exercise plan or diet change during the period of study. The coffee powder that people normally use is prepared after roasting some green coffee beans. The extract is obtained from green coffee bean at a temperature of about 70°C for 2 hours using 70 percent of ethanol. A green coffee bean extract is a yellowish brown hygroscopic powder that has high polyphenols levels referred to as hydroxycinnamic acids, which contains caffeic and chlorogenic acids. Green coffee bean extract and weight loss A Japanese scientist, known as Hiroshi Shimoda, did a research about the green bean extract and discovered that it facilitates body weight loss. The weight loss is brought about by some two natural chemical compounds found in the green coffee bean. Since coffee beans are not roasted, they still have their natural chemicals that can otherwise be lost if they are roasted. The two natural chemicals are chlorogenic acid and caffeine which jointly lead to loss of weight. The caffeine in coffee works by stimulating the release of fatty acids from the fats stored inside the body. The chlorogenic acid, on the other hand, helps the liver to process the released fatty acids thus resulting in weight loss. If one consumes 1kg of food containing 10g of green bean extract daily for 14 days, then the increase in weight can be suppressed by about 35 percent. Other Health Benefits of Green coffee bean extract Anti-aging Benefits The chlorogenic acids in green coffee bean destroy any free radicals formed within the body through metabolism. If such free radicals are left, they can destroy the cell membrane and trigger some ageing symptoms. By destroying such harmful radicals, green coffee bean extract actually slows down the natural aging process. Some studies also reveal that the absorption capacity for oxygen radicals by the green coffee extract is twice that of green tea or grape seed extracts. Reduce Blood Pressure Animal research also reveals that chlorogenic acids in the green bean extract helps in alleviating high levels of blood pressure. Considering the results of this particular study, some research was further conducted on human beings. This experiment, performed on people with mild hypertension, revealed that the consumption of the green coffee extract supplement contributed in lowering high blood pressure levels. When a dose of about 185mg of green coffee extract supplement was consumed, the extract proved quite effective in reducing symptoms of hypertension. Hence they are often used for the treatment of the same.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2734) What Are The Health Benefits Of DMAE?
Date:
April 26, 2012 12:57 PM
DMAE Dimethylaminoethanol or DMAE is anorganic compound that is metabolically produced by the adrenal glands, testes and the brain in small quantities. It is converted into testosterone, estrogen and cortisone by the body. It is a known fact that the liver processes DMAE into choline, but the molecule thus produced is charged and cannot break the blood-brain barrier. Studies have shown that DMAE methylated in the brain acts as the precursor for the manufacture of acetylcholine, a neurotransmitter that plays a key role in the conduction of signals in the brain as well as the nervous system. DMAE also stimulates phosphatidylcholine, a crucial part of cell membranes. However, the DMAE naturally produced by the body is sufficient only to maintain healthy brain and functions. It will not improve their functions. Though DMAE is found in fish such as salmon, anchovies, and sardines, supplementation in the pill form is important because of the practical difficulties having these foods in the right form and quantity on a daily basis to derive the benefits. DMAE supplements for oral consumption are through stores that sell health foods and groceries. Daily consumption of DMAE in the supplement form provides a number of benefits to the body. Some of the benefits are as follows: It helps prevent as well as treat cardiovascular problems and boost the body's immune system because of its strong antioxidant properties.It protects cells from the harmful effects of free-radicals by helping them retain the nutrients that are essential and expelling waste.As a precursor in the production of the neurotransmitter acetylcholine, it supports the functioning of the brain in a number of ways. It increases a person's attention span, relieves behavioral problems and hyperactivity or attention deficit hyperactivity disorder. It is also helpful in treating memory lapses and Alzheimer's disease. It helps stop production of arachidonic acid which is responsible for wrinkling and aging of skin. Topical creams containing DMAE help tighten skin and reduce wrinkles and fine lines.It is found to be effective in burning fat because of its involvement in the production of acetylcholine. It increases the metabolism in the body because of its thermogenic effect.It can be beneficial as an anti-inflammatory as well.It can reduce the amount of sleep required for a person by up to one hour.It can safely be used as a substitute for anabolic steroids. research Research studies have shown that consumption of 200 to 500 mg of DMAE on a daily basis is helpful in improving health. However, it is important to start with a low dosage of DMAE and then gradually increase the dosage level to the optimum level. Higher dosage can cause headaches, insomnia and muscle tension. People suffering from conditions such as schizophrenia, mental depression and epilepsy should not have DMAE supplements. Pregnant and lactating women also should not have DMAE. Summarizing, consumption of recommended amounts of DMAE is believed to be safe. Side effects due to consumption of DMAE are rare and not generally serious. However, it is important to use high-quality supplements in order to increase DMAE levels in the body and reap the benefits.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2638) Can Saw Palmetto Out Perform Synthetic Treatments For Enlarge Prostate?
Date:
October 03, 2011 02:53 PM
Since the ancient times, Saw Palmetto has been long used as an edible food and an herbal plant. The most common use of this herb is for the improvement of benign prostatic hyperplasia or BPH. This illness usually results to problems with urination and sexual activity. The enlarged prostate may obstruct the flow of urine making urination difficult and even painful for some. It can also affect the individual’s sexual activity because the prostate is the gland responsible for producing seminal fluid which is a component of the male ejaculate. The mechanism of action of this herb in improving the condition of benign prostatic hyperplasia is that it inhibits the action of the enzyme called 5 – alpha – reductase which is involved in the abnormal growth of the prostate gland. Another theory on its action in relation to benign prostatic hyperplasia is that it can effectively interfere with the chemical substance called dihydrytestosterone. One of the reasons of prostate enlargement is that there is increased amount of the hormone testosterone that binds to androgen receptor sites. Saw Palmetto extracts have been found to bind with androgen receptor sites and act as a phytoestrogen. Therefore, if the receptor sites are already filled up, testosterone hormones will not be able to attach to these receptor sites and provide an effect to the body. Hence, if testosterone is minimized, enlargement of the prostate gland will also be controlled. Benign prostatic hyperplasia is a serious health condition. Several prescribed medications are available to treat this illness. Indeed, saw palmetto extracts may be helpful but this supplement must not be used as a substitute for your prescribed medications. It may have similar actions with BPH drugs such as Finasteride but its potency is different. Clinical studies have also revealed that saw palmetto supplements do not directly decrease the size of the prostate gland but the lining inside the gland. It thins the inside layer of the gland thus minimizing pressure that rests on the urine tubes or urethra. Saw palmetto is generally safe. However, since it can cause significant changes inside the body, it is important that you should talk to your doctor first before using this supplement, most especially when you already have BPH. You have to consult your doctor and discuss with him or her about your current health status, past medical history, familial health history and other medications taken whether prescribed or not. Dosage of the supplement is also best determined by your doctor. This will greatly help in the avoidance of untoward effects and unnecessary negative interactions with the other drugs you are taking.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2473) What is Dandelion Tea Good for?
Date:
March 08, 2011 02:38 PM
Dandelion Root
Dandelion tea must be best known as a detoxifying beverage that has been associated with improving liver and kidney functions. In the old days the plant is often considered a pesky weed, but today health organizations, such as the European Scientific Cooperative on Phytotherapy, have endorsed its efficacy in relieving liver problems among others. The tea produces a pronounced bitter taste and is often sweetened, but it also packs large quantities of micronutrients. Peoples from the Old World are no stranger to dandelion tea, but the plant species are native to both Europe and North America. What we refer to as dandelion comprises a large group of flowering plants. The two most notable species are Taraxacum officinale and Taraxacum erythrospermum, both of which are used to make dandelion tea. The fact that it can be found right in your yard is the reason why health magazines regard this herb as one of the readily available nutritional powerhouses. Maintains Intake of Nutrients during Weight Loss Dandelion tea has been noted to contain significant levels of vitamins and minerals, the reason why it is popular among individuals who are following a weight-loss program. Many people seem to overlook the fact that depriving themselves of important food sources, such as whole grains, compromises their daily intake of dietary nutrients. Chronic dieting is particularly dangerous in the long run even for those who used to be physically healthy. Dandelion tea offers a solution to people on a diet by meeting the RDA for vitamin A and K and providing up to 30 per cent of vitamin C and vitamin B7. It is also rich in minerals like calcium, potassium, and iron. Promotes Excretion of Toxins through Diuresis Not surprisingly, dandelions have been used to aid a long list of symptoms and diseases, and it has been reputed as a natural diuretic for centuries. Due to its worldwide distribution, it is one of the few herbs that have earned visible presence in traditional medicine of the East and the West, and its use has always had something to do with the proper functioning of the liver and the kidneys. The bioflavonoids found in dandelion remove toxins from the liver, like ethanol metabolites, and facilitate their excretion through the urine. Facilitates Absorption of Bioactive Compounds Health professionals often point to the nutritional content of dandelion tea and other products from the herb. Most species of dandelions have been documented to be completely edible, and the quantities of bioactive compounds present in them have been compared with vegetables like spinach and broccoli. Consumptions of dandelions have even been considered tantamount to intake of dietary supplements as they are rich in phytochemicals that display the activities of many known polyphenolic substances found in black and green teas and other foods rich in antioxidants. While the plant contains high quantities of protein, carbohydrates, and fiber, the tea has been tied to more effective absorption of these bioactive compounds, making it an ideal beverage to match with any food source.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2249) Can N-Acetyl Cysteine Boost Liver Health And Function?
Date:
February 10, 2011 12:31 PM
N-Acetyl Cysteine (NAC) And The LiverN-Acetyl Cysteine or NAC is an antidote for poisonous effects of paracetamol overdose. It targets the cells in the liver, raising their capacity to deal with harmful metabolites. There are a number of researches well underway that scrutinizes a variety of medical conditions for which this compound could be of use. It is a known precursor of antioxidants and in itself a scavenger of peroxides and free radicals. Hepatocytes are the cells that take on most of the functions of the liver and account for more than 70 per cent of the liver’s total mass. These cells are responsible for the presystematic metabolism of drugs, also known as the first-pass effect, rendering most drugs innocuous before they are released into the bloodstream. The total amounts of bioactive substances that are distributed to the rest of the body are also largely regulated by hepatocytes, notably carbohydrates. In addition, they are involved in the biosynthesis of protein, cholesterol, phospholipids, and bile salts as well as the functional reserves for protein. Hepatocytes and Toxins Certain drugs produce toxins when broken down by hepatocytes. A classic example is the metabolism of ethanol into acetaldehyde, which is a toxic compound, a probable carcinogen, and an air pollutant emitted by combustion of cars and tobacco smoking. While hepatocytes are known for their detoxifying responses to toxic substances entering the body, the metabolism of toxins actually takes up a great deal of time, resulting in certain toxins getting released into the bloodstream prior to first-pass effect. That being said, continued exposure to toxins wears down hepatocytes, and high concentrations of what we refer to as poisons is certain to bring damage to the liver. This is what happens during overdose of paracetamol, or acetaminophen. In an effort to metabolized excessive amounts of the drug, the liver cells produce by-products that are essentially poisons, which under normal circumstances can be contained well.
NAC and Glutathione ProductionThe major antioxidant synthesized by the human body called glutathione comes to the liver’s defense when toxic by-products are produced. Hepatocytes in particular are so dependent on glutathione in the quenching of toxins that it has been observed that any challenge to the manufacture of this endogenous antioxidant will ultimately result in liver failure. Glutathione is released by hepatocytes in large amounts especially during the metabolism of alcohol and drugs, but during overdose the ravaging activities of ethanol or drug metabolites overwhelm the detoxifying effects of antioxidant reserves in the body. Simply put, the defense mechanisms in the employ of the body have limits. NAC resolves this problem. The presence of NAC in the body augments the liver’s ability to produce the needed amounts of glutathione to effectively counter the harmful properties of invasive substances. In fact, the liver completely recuperates in a matter of weeks even after life-threatening conditions given that NAC is introduced in the human body in time to avoid subsequent damages to other vital organs. Indeed its application has proven to save lives in fatal cases of paracetamol poisoning. N-Acetyl Cysteine is available at your local or internet vitamin store in capsule or tablet forms. Always choose name brands like Source Naturals to ensure quality and purity of the product you buy for better liver health. Have you had your NAC today?
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2235) Fight Free Radical Damage From Toxins With Vitamins And Herbs
Date:
July 28, 2010 11:34 AM
There are many things that destroy the immune system. Each day we are bombarded with them in many forms. The following are some of the most common ones that are encountered. Agene, also known as Nitrogen Trichloride, is used to bleach flour and give it a white appearance. Unfortunately, it can cause epileptic-like fits along with failure of muscle coordination. Excessive use of alcohol also severely impairs the immune system. It increases susceptibility to infection and weakens the central nervous system. Alcohol promotes chronic lung disease, malignancies of the neck and head, intestinal problems, hypoglycemia, diabetes, liver disease, and a whole variety of other problems. B vitamins, folic acid, niacin, vitamin E, magnesium, zinc, and protein are depleted by alcohol. All of these nutrients play a huge role in immune health. Aspartame breaks down in the digestive tract into a toxic material known as methanol. In order to prevent methanol from metabolizing into formaldehyde, a poison, a person needs to take another poison, ethanol. Glutamic acid is a substance that is found in monosodium glutamate, a flavor enhancer. It affects the central nervous system and can trigger depression, gloomy fantasies, and rage for as long as two weeks following the ingestion of monosodium glutamate. High-diet fat intake increases the levels of bile acids in the colon. This breaks down into deoxycholic and lithocholic acids, both of which are cancer-causing elements. This can cause cancer of both the colon and the rectum. A diet that is high in animal protein and fat can cause cancer of the pancreas, breast, gallbladder, ovaries, uterus, prostate, and leukemia. Junk food such as sweets, white flour, and white sugar products, put a double amount of stress on the body. When too much junk food is eaten, the appetite for good, wholesome food is dulled. Caffeine decreases immunity in the body, with fibrocystic breast disease being connected with the consumption of foods that contain caffeine. It is often caused by the chemicals methylxanthine, theophylline, and theobromine, which are found in coffee, black tea, cola drinks, chocolate, and other soft drinks. These elements act on hormones that cause breast tissue to develop fibrocystic lumps. Caffeine takes away the body’s own use of iron and inositol, and is often suspected of causing cancer in the pancreas. Food dyes and flavorings are the culprits in behavioral problems that occur in children and adults, with some of these problems being learning disabilities and hyperactivity. Sodium nitrate is a preservative that is often found in cured meats like hot dogs, bologna, and ham. It has the potential to produce permanent epileptic changes in brain activity and damage the central nervous system. High protein diets can deplete calcium in the body, especially when the source of protein is an animal product. There are concentrated doses of hormones and antibiotics that are found in beef which suppress the immune system and promote tumor growth. Poly-unsaturated fats undergo a process that produces rancidity in oils. This process releases dangerous free radicals, which eventually lead to cancer. Heavy metals like lead and mercury can cause serious damage to the nervous system, with even small amounts being considered toxic. Lastly, the wide use of vaccinations and antibiotics is considered to be one of the main causes of immune system disorders. Our bodies are under constant attack by our toxic environment. Fortunately, with regular vitamin and herb use, one can help the body restore its immune system to proper function so we can live a happier healthier life.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2174) L-Methionine
Date:
May 02, 2009 11:41 AM
Methionine is an essential amino acid, meaning that it is not synthesized by the body, and so has to be taken as part of your diet. It also contains sulfur, one of two sulfur-containing amino acids that can form proteins, the other being cysteine. It is a precursor for taurine, which is an aminosulphonic acid, and not strictly an amino acid, which together with cysteine supports the health of your cardiovascular system and helps to eliminate toxins from the body. Maintenance of Cell Membranes It is also an important intermediary in the maintenance of cell membranes. Phospholipids are fat-soluble components of the cell membrane, phosphatidylcholine being a very important example. Also known as lecithin, this substance is derived from choline, itself biosynthesized in a chemical pathway involving S-adenosylmethionine. This substance is made in the body from ATP (adenosine triphosphate) and methionine with the help of the enzyme methionine adensosyltransferase. Known as SAM (or SAM-e), S-adenosylmethionine employs a number of metabolic pathways in its reaction, though generally aminopropylation, transmethylation and transsulfuration. These add aminopropyl, sulfo and methyl groups to a number of substances, the most common being the methylation of proteins, nucleic acids and lipids. Phosphatidylcholine is produced by the enzyme-catalyzed sequential methylation of phosphatidylethanolamine, SAM donating the methyl groups. The maintenance of the integrity of the cellular membrane by phosphatidylcholine is critical to all of the basic processes in human biology, including communication between cells, flow of information and bioenergetics. A by-product of this reaction is homocysteine, formed in the liver from the S-adenosylhomocysteine that SAM is changed to after donating methyl groups. Excess homocysteine in the blood can create the risk of myocardial infarction and cardiovascular disease. SAM is also of use in the treatment of depression and of arthritis. Muscle Development Creatine is a substance well known to athletes as being useful in provide short-term energy for high-intensity training. Although available in the diet, about 50% creatine used by the body is biosynthesized from methionine and two other amino acids, glycine and arginine. It allows a burst of energy lasting about 10 seconds, carried out without the use of glycogen reserves or fatty tissue. Glycine and arginine combine to release ornithine as a by-product, and form guanidino acetate. SAM donates a methyl group to the latter to form creatine, about 95% of which is then stored in the skeletal muscle tissue. The stored creatine phosphate has the effect of allowing the muscle cells to hold more water, which also enables an enhanced level of protein synthesis, and hence an increase in muscle bulk, which also results from the increased blood flow resulting from the short-term high-intensity exercise that creatine allows. Creatine can also increase the levels of MRF4 (myogenic transcription factor), resulting in an increasing in the myonuclei provided by satellite cells to damaged muscle tissue, that not only repair damaged muscle fibers, but also increase their ability to grow. Detoxification of the Liver Substances that help the liver to process fats, or lipids, are known as lipotropic, and the important lipotropics in human biochemistry are imositol, betaine, choline and methionine. They prevent fat from accumulating in the liver, and methionine is also useful in its effect of glutathione. This is a substance that helps the liver to neutralize toxins, such as excessive doses of acetaminophen, and its supplies are regulated by methionine. Methionine and Autism Research into autism is closely studying the Methionine/Glutathione Transsulfuration Pathway. This pathway is a very important biochemical means of detoxification, whereby toxins are methylated and then excreted. This pathway seems to be disrupted in autistic individuals. Not only that, but disruption can lead to oxidative stress which results in many health problems. An example of this is the build-up of the oxidant homocysteine when there is insufficient Vitamin B6 to convert it into cysteine. This has been discussed previously, and is discussed again below. Miscellaneous Benefits Although research is in its infancy, it appears that AIDS sufferers also have decreased levels of methionine in their blood. It is believed that the process of AIDS could be linked to this, particularly the dementia that can occur as a result of the deterioration of the nervous system. It is also hoped that it can help with some symptoms of Parkinson's disease, and pancreatitis. Initial research into this use of methionine has been very promising, as are studies into its use for urinary tract infections. It appears to operate like cranberry in this respect, preventing bacteria from attaching to the cell walls and multiplying in the urinary tract. Methionine is believed to be essential for the formation of collagen, and for healthy pliable skin, hair, nails and other forms of connective tissue. For this reason it is often used as a supplement for the treatment of arthritis, although an excess should be avoided for reasons discussed above. S-Adenosylmethionine generates homocysteine during the biosynthesis of phosphatidylcholine, and this can cause cardiovascular problems. So stick to the recommended doses when you use methionine as a supplement. Used properly, and according to instructions, it offers many health benefits, and can also be used to bulk up your muscle tissue and give increased energy when you need it most. Dietary sources include fish, eggs, lentils, onions, garlic, meat, seeds, spinach and yoghurt. A good supplement would be from 800mg - 1000mg per day, and is best taken along with a B vitamin complex, or at least folic acid and vitamins B6 and B12, in order to prevent the increased generation of homocysteine. Methionine also promotes the excretion of estrogen, so is a possible supplement for women on oral contraceptives that lower the production of this hormone. The elderly might also benefit from a supplement although, if taken for any specific condition, your health professional should be consulted first, as they should be for any supplement. Nevertheless, methionine is a very useful supplement, and can be taken to prevent a large number of conditions. Research is continuing on its effect on AIDS patients, and Parkinson's, and it is hopeful that it will one day be recommended to help people suffering from these conditions.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2002) DMAE
Date:
June 14, 2008 03:22 PM
DMAE (dimethylaminoethanol) enhances mental function through the improvement of concentration, mental clarity and mental alertness. It is also a mild brain stimulant because it increases and sustains the energy levels in the brain. It also improves the level of restful nighttime sleep because the sleep is deeper and less time is needed to reach a rejuvenated state. DMAE helps to boost mental function through an increase in the levels of acetylcholine and choline. These are the brain’s chemical messengers. Because of DMAE’s ability to stimulate mental cognitive function, it also has been shown to improve learning, increase intelligence and elevate mood. DMAE Benefits: * Accelerates mental processes * Decreases irritability and overactivity * Does not cause drowsiness * Improves concentration * Improves IQ * Increases attention * Relieves mild depression * Aids in long-term treatment of schizophrenia It is believed that DMAE may also increase physical energy. Athletes and other active individuals are using DMAE more and more because of its ability to enhance these brain functions. The connection between the mind and muscles is a means to focus on form and reduce the risk of injury. So, when the mind is enhanced, it communicates better with the muscles to improve and refine function. Due to DMAE’s mild stimulating effect on the brain, athletes report that it is a good alternative for a quick lift instead of coffee. They also believe the stimulating effects last longer than they do with caffeine. DMAE used as a mild stimulant is also safer and healthier than caffeine. How It Works: DMAE, once consumed, is transported to the liver where it is converted into choline through the process of metabolism. A small amount is then converted into acetylcholine, which is a brain transmitter. Through this process, DMAE increases the levels of these brain transmitters (neurotransmitters). This causes a boost in mental cognitive function and memory. Acetylcholine is also responsible for helping to conduct nerve impulses in the brain. Choline is also converted in the brain into phosphatidylcholine. This chemical rebuilds and protects existing cell membranes inside the brain. DMAE has the ability to cross the blood-brain barrier faster than choline. Through this quicker travel, DMAE enhances cell protection and repair and helps our brains function better and create enhanced, positive behavioral changes in most people. Other DMAE Uses: DMAE is being studied for use in aiding a movement disorder in Parkinson’s patients. This disorder, called dyskenesis is caused by L-Dopa, which is administered to treat the effects of the disease. DMAE seems to counteract dyskenesis effectively and safely without interfering with the benefits of the therapy. DMAE is proving to reduce the effects of other disorders that involve involuntary movements. Two of these disorders being treated are blepharospasm (eyelid twitching) and benign essential tremors. Age spot sufferers may find hope for treatment of their condition as well. DMAE has been found to inhibit the formation of pigment caused by aging (lipofuscin) and liver spots (lentigo). It may actually flush lipofuscin from the body, causing the skin spots to disappear over a few month’s time. DMAE is being studied for its possible ability in helping to reduce cognitive impairments related to age. Aside from increased mental cognitive function, research has shown that DMAE may also be useful in treating the following conditions. * Alzheimer’s disease * ADD (attention deficit disorder) * Hyperactivity
The use of DMAE as a regular dietary supplement is increasing steadily. All of its benefits in aiding mental cognitive function and brain stimulation are an attractive quality for everyone. Additional research showing that DMAE is useful in treating debilitating conditions such as Parkinson’s gives us new hope. As research continues and more new uses for DMAE are discovered, its popularity will continue to grow as well.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1816) Lipid content by percentage
Date:
May 13, 2008 04:54 PM
Phosphatidylcholine (PC) 68% Assists in the introduction of DHA into the or Marine Lecithin heart muscle. Protects the mitochondria from oxidative damage, decreasing the impact of auditory and visual aging. Phosphatidylethanolamine (PE) 11% Combined with PC, helps in the building of the myelin sheath. Phosphatidylserine (PS) 9% The most widespread of all membrane PLs, protects from ischemic attacks (stroke) or age-related dementias. Phosphatidylinositol (PI) 5% Acts on the regulation of cellular calcium. Has shown its effectiveness on obsessive compulsive disorders, panic attacks, depression, manic depression and Alzheimer’s disease. Sphingomyelin (Sph) 5% Its pro-apoptotic activity decreases the risks of coronary hear t disease and cancer of the bowel (colon). Decreases parietal cell toxicity of bile salts. Sphingolipids are mostly present in the myelin sheathes.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1789) Beta Carotene Is The Safe To The Liver Form Of Vitamin A
Date:
March 19, 2008 08:17 AM
The fact that beta carotene is stated to be a safe form of vitamin A suggests that vitamin A is in some way unsafe. In fact an overdose of vitamin A can lead to any one of a number of conditions, including nausea, jaundice, vomiting, abdominal pain and headaches. This vitamin is fat soluble, and so any excess is not easily washed out of the body but can build up in the tissues. Toxicity in the liver can occur at fairly low concentrations, and the toxicity of the vitamin is increased by excessive alcohol intake. However, toxicity only occurs with vitamin A already formed such as that obtained from liver. There are several forms of vitamin A, including the retinoid form originating from animal sources and the carotenoid forms that have a vegetable origin. Carotenoids are converted to vitamin A in the liver, but the higher the concentration of beta carotene in the body, the smaller the percentage that is converted to vitamin A, so beta carotene is a safer source of vitamin A than retinoids. It is only the finished form of vitamin A that is toxic, and beta carotene is therefore self-regulating in its production. This vitamin is stored in the body in the form of the alcohol (retinol) and of retinyl esters. Studies have indicated that as much as 95% if the stored vitamin is in the form of the ester. The liver is responsible for releasing vitamin A to the body as it is required. One of its better known effects is on vision, and the old wives tale that carrots help you to see in the dark has an element of truth in it. In order for it to aid vision, retinol is oxidized to the aldehyde, retinal, that forms a complex with a molecule of opsin, a light sensitive protein found in the retina. Rhodopsin, as the complex is called, is an essential component of the biochemical chain of events that lead to the perception of light. It is extremely sensitive, and enables you see in very low levels of light. In other words it is essential for good night vision, so carrots do help you to see in the dark! When a photon of light hits a molecule of rhodopsin, it leads eventually to an impulse being sent up the optic nerve to the brain. One of its properties is its reaction to white light. When rhodopsin is exposed to white light it loses its pigmentation, and hence its photoreceptor properties and can take 30 minutes to regenerate. That is why you lose your night sight if your retina is exposed to bright light. The more rhodopsin you can generate the quicker you develop night sight. The other biochemical processes of the vitamin include the synthesis of some glycoproteins and maintenance of normal bone density. Without vitamin A, calcium is not properly absorbed by the body and glycoproteins are involved in this process. A deficiency of vitamin A can lead to the abnormal development of bone and other health problems, so there are limits between the levels of vitamin A in the body that must be maintained: above or below these limits will lead to health problems, some of which can be extremely serious. Most of the biochemistry of vitamin A in the liver is initiated by the presence of alcohol, and otherwise it is though to passively store the vitamin until needed when it is released into the blood. There are several ways in which the presence of alcohol allows the liver to deplete its store of retinol, but generally there are a number of enzymes that, in the presence of ethanol, can render vitamin A into a water soluble form that is excreted by the urine. The benefits of vitamin A other than its effect on night sight and the healthy development of bone tissue, includes a powerful antioxidant effect that neutralizes free radicals that can destroy body cells. These free radicals are generated by the body’s metabolism in generating energy from blood glucose, and are also created through exposure to pollutants such as cigarette smoke and traffic fumes. They are electron deficient, so when they are generated they grab an electron from tissue close by which destroys the cells involved. This can lead not only to the appearance of premature aging as the skin cells are damaged but also to serious health problems such as atherosclerosis and some forms of cancer. Vitamin A helps to protect against these by destroying the free radicals before they can do damage. It also helps build up resistance against infections by supporting the immune system. Beta carotene is converted to vitamin A either by cleaving at the center of the molecule, or by breaking it down from one of the ends. This latter process is carried out in the small intestine, and the resultant vitamin stored in the liver in the ester form. Only a proportion of what you eat is converted to retinol ester in this way, and the more beta carotene you consume, the less is converted, so you can never suffer from an overdose of beta carotene-derived vitamin A. It might turn you yellow, but you won’t suffer from excess vitamin A since the excess beta carotene is stored in your body fat, including the subcutaneous fat reserves. Alpha carotene can also be used in the synthesis of vitamin A, but not as actively as beta carotene. The best natural sources are fruits and vegetables, especially the red, yellow and orange varieties such as carrots and apricots, and also the leafy green vegetables, although supplements are also a convenient way of maintaining your beta carotene uptake. It is a much safer supplement than straight vitamin A for the reasons explained earlier. The supplement is not useful just for its antioxidant effect, but also for its ability to protect you from excessive exposure to the sun. While not as effective as a good sun blocker, beta carotene does provide some protection. There is no doubt that beta carotene is a safer way to maintain an adequate vitamin A uptake due to the fact that you cannot take an overdose, since an overdose of beta carotene does not translate into the same dose of vitamin A, and the change is self-regulating. It is therefore safer to obtain your vitamin A needs from colored fruits and vegetables or beta carotene supplements than from eating liver, from which the retinol is in a form that can cause damage in the event of consuming an excess. The old adage that you should never eat polar bear livers is a true one, and certainly has a provable scientific basis, so use beta carotene as your main vitamin A source for maximum health benefits in the safest possible way.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1725) Apple Cider Vinegar to Fight Heart Burn
Date:
February 16, 2008 08:55 AM
Strange as it may seem, apple cider vinegar can be used to fight heart burn, even though that type of vinegar is composed of acetic acid the same as any other. It wouldn’t seem logical to use an acid to alleviate a condition caused by excess acidity in the stomach, but all will be clear shortly. First, let’s have a look at what cider apple vinegar is, and what health benefits it can impart to the body. There is more to the old maxim regarding an apple a day than most appreciate. Although an orange has more vitamin C, apples have a lot going for them. They not only contain the soluble dietary fiber and prebiotic pectin, that can help reduce blood cholesterol levels, but are also rich in vitamins and minerals. Many consider apple cider vinegar the form of the apple that provides its ultimate health benefits. Hippocrates himself has written of the health benefits of apple cider vinegar and used it for the benefits to health that it imparted. That goes back almost 2400 years, to an age when the biochemistry of the body was unheard of and even the alchemists had yet to work their magic. There was no surprise then that an acid could be used to increase the alkalinity of the body since the terms had yet to be understood, let alone invented. The later applications of vinegar followed a path that would be expected of a substance recognized as a form of medicine, and it has been poured over wounds to sterilize them from early in history, and by people of the 14th and 17th centuries to protect themselves against the Black Death and the Great Plague respectively. It was believed by people in these times that the disease was transferred by breathing in the ‘ill vapors’ and that a vinegar-soaked cloth over the face would protect them. Many people, associate vinegar with ‘bad wine’ or solutions of acetic acid, generally 5%. But how is real cider apple vinegar produced? All vinegar has acetic acid as its key ingredient. The reason that it can be produced from wine is that acetic acid is produced naturally by the fermentation of ethanol, or ethyl alcohol, the main alcoholic product of the fermentation of sugars. If the fermentation of wine is allowed to continue after the sugar has been used up, then the yeast will act on the ethanol and convert it to acetic acid. In fact the word comes from the old French ‘vin aigre’ or ‘sour wine’, due to it resulting from the undesirable continuing fermentation of wine. The concentration varies according to the use it is put, though commercial pickling vinegars can be distilled to any required concentration of acetic acid. Apple cider vinegar is obtained by the over-fermentation of apple must usually used for cider, and can be obtained either the clear filtered form, or unfiltered with a hazy light brownish color. Although the manufactured distilled vinegars consist of acetic acid at various concentrations, natural vinegars contain by-products of the fermentation process such as citric and tartaric acids. However, none of this explains why apple cider vinegar should help to cure heartburn. The first thing you should keep in mind is that this type of vinegar has some nutritional value that will be explained later, but also that it is less bitter than many other types of vinegar and many enjoy drinking it with a small amount of honey as an energy pick-me-up and also to prevent various digestive problems that it appears to alleviate such as bloating and diarrhoea. The reason that many people experience heartburn is due to the body finding that that the acidity of the stomach is lower than it should be to digest a meal. There might be several reasons for the body believing this, such as drinking too much milk during the meal and thereby neutralizing some of the acid while also introducing more fat to be digested. The body reacts by injecting more acid into the stomach. Excessively spicy foods or alcohol can cause the same effect. Stomach acid is concentrated hydrochloric acid that is very corrosive and can even dissolve a nail. If your stomach is slightly full, the acid causes a slight, but not full, reflux and you get the burning sensation known as heartburn due to the corrosive effects of the very strong acid on the esophagus, which is not protected by the stomach lining that is designed to withstand it. Sometimes the excessive acid in your stomach will cause the bottom of the esophagus to open, allowing some of the stomach contents into the esophagus giving the horrible burning sensation. That sensation is acid corrosion of your body tissue, but it is rapidly repaired and does no lasting damage unless it is chronic when you have to see your doctor. Since heartburn is caused by excess acidity then, it will seem strange that you can use an acid to alleviate it. However, keep in mind that your heartburn is due to the body (brain) being convinced that there is insufficient acid in your stomach. If you introduce a weak acid, then you can convince your brain that the acid has been brought to a satisfactory level and so it will stop sending signals to the stomach lining cells that secrete the HCl. If you remember what I asked you to remember above, regarding the traditional uses of apple cider vinegar and how easy it is to drink, then that vinegar is the ideal acid to take. It floods the stomach with acetic acid and signals pass back and forth between the stomach wall to the brain and back again to the effect that the stomach has enough acid and so no more hydrochloric acid need be secreted. Had you treated it with milk or even an antacid, it would have worked initially, but eventually the signal would be initiated and the lining would secrete more HCl. With an antacid that can occur after the stomach contents have been passed on, but although it has had its effect, your food will have been poorly digested, and so the better remedy is likely not an alkaline antacid but a weak acid such as apple cider vinegar. That’s how it works, but what other benefits does it bring to you. For starters it is a good source of potassium which is essential to maintain a proper cardiac rhythm. Potassium can also help to maintain a good blood pressure, and it is necessary for healthy nails, hair and teeth, and also helps to repair damage to soft tissues and to allow cells to repair internal tissue loss. Potassium is an essential mineral, although there is normally sufficient in a healthy diet. However, if somebody is displaying the symptoms of potassium deficiency then this form of vinegar can help to resolve the problem. The elderly especially can benefit from a regular dose. Other than its antiseptic effect, the most common popular use of apple cider vinegar, however, is to fight heart burn and in that respect it is very effective, even if it seems a bit of a paradox.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1719) Neptune Krill Oil - EPA and DHA Rich!
Date:
July 02, 2007 12:43 PM
Complete List of Now Vitamins Starting at 40% OFF. The oil of Atlantic Krill, a zooplankton crustacean, contains one of the most unique nutrient profiles ever discovered. In addition to rich concentrations of EPA and DHA, krill also boasts an impressive amount of phospholipids, all-trans retinol vitamin A, natural vitamin E, and omega-9 fatty acids. The oil is an excellent source of esterified astaxanthin—a powerful, immune supporting carotenoid that has been clinically proven to quench singlet oxygen radicals within cell membranes. The potent arrangement of naturally occurring compounds exhibits strong synergist properties that support and protect many of the body’s most vital system.*At the most basic level, krill oil contains compounds that the body needs in order to construct healthy cell membranes. By nature, omega-3 essential fatty acids can be particularly sensitive to oxidation. Atlantic krill, however, contain antioxidants and Carotenoids that bind to these fatty acids, thus improving the biological stability. Accordingly, studies have shown that as much as 95% - 95% of the EPA and DHA in krill oil is capable of being absorbed for use throughout the body. Among its most impressive qualities, Neptune Krill Oil contains phospholipids that are rich in EPA and DHA, and structurally similar to those produced by the human brain. The most significant include phosphatidyl Choline, phosphatidyl Inositol, and phosphatidyl ethanolamine. Researchers believe that their unique structure and ability to cross the blood-brain barrier make it possible for those compounds to support brain and cognitive health.* Now Vitamins Neptune Krill Oil is manufactured under the strict quality control, and tested to be free of potentially harmful levels of mercury and other heavy metals, PCB’s, dioxins and other contaminants.
100% Pure Neptune Krill Oil
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1579) Which Calcium is Best?
Date:
October 17, 2006 03:52 PM
Customers walking into a health food store today are faced with a vast array of calcium supplements. They might ask: which one should I pick? Which one is best? Not easy questions to answer. All calcium forms will accomplish the same task: providing your body with a nutrient that it needs to build healthy bones and teeth; however, which form of calcium has the features that you want in a calcium supplement? Looking at shelves of calcium products is kind of like shopping for a car; there are many makes and many models—some are basic and others are more sophisticated. Fortunately, there are many forms of calcium to satisfy your needs. Like the car lot, a health food store offers many options; therefore, you have to select a calcium product that consumers will feel confident in taking regularly and that will provide the most benefit. Some consumers have done research and will come armed with information. They have already made choices based on advertising, word-of-mouth or an article they have read. They already know the form of calcium they want, be it a “Ferrari” or a “Ford.” If the client doesn’t have a specific preference: asking these basic questions will help in the selection process: 1. Do you prefer tablets, capsules, softgels, liquid or powder?
2. Do you have high or low stomach acid?
3. Do you have absorption issues?
What is calcium? Calcium (Ca) is one of the most important minerals found in our bones and teeth—99 percent of body calcium is found there. But the calcium molecule does not like to travel alone and, in its more basic state, it comes bounded to carbon (C), Oxygen (O), and/or hydrogen (H) molecules or in more complex form, it is bonded to organic or amino acids that act as stabilizing carriers. On most labels, the amount of calcium listed actually indicates the pure or elemental calcium because it is that amount of the calcium that is deemed important to our daily supplementation, not the complex of the materials with which it is bonded. Where does calcium come from? Other than the calcium found in bone, the only natural form of calcium found in nature is calcium carbonate, a calcium molecule bonded to one molecule of carbon and three molecules of oxygen (CaCO3). One of the most common minerals on the face of the earth, calcium carbonate is called calcite, aragonite or vaterite by geologists. In its geological form, it constitutes approximately four percent, by weight, or the earth’s crust. Commercial sources of calcium carbonate used to make supplements are: limestone, dolomite, oyster cell, egg shell, coral and sea water (have you ever seen that white deposit left by hard water? That’s mostly calcium carbonate). Calcium carbonate is the starting material for all other forms of calcium supplements. From this starting material, calcium can be reduced to more concentrated forms, such as oxide or hydroxide or it can be chelated (bonded) to organic acids and amino acids to help support enhanced absorption. Lets look more closely at the different forms of calcium that are available as supplements. Calcium Oxide (CaO): this form is 71 percent elemental calcium and is also called “lime” commercially. This is one of the oldest and most inexpensive forms of calcium used in a variety of commercial applications and it is occasionally used in supplements where space and price are a factor. It sometimes can be found in inexpensive mass market calcium/mineral combinations or multivitamin/mineral products and in a unique algal calcium from Japan. Unfortunately, CaO is a strong alkali that may cause stomach distress, which is why it isn’t often used in health food supplements. Calcium Hydroxide (CaHO): at 54 percent elemental calcium, it is the next highest source of elemental calcium and is also known commercially as “slaked lime.” It is used where space is an issue. Although it is also a strong alkali, it is more stable than calcium oxide. It is most often used as a component of multi-mineral formulations or in addition to other forms of calcium (i.e., calcium citrate) to provide potency where space is an issue. It is not often used as a single ingredient in health food supplementation. This is for people who want a high dosage of calcium from a minimum amount of pills in multi-mineral formulas. Calcium Carbonate (CaCO3): at 40 percent elemental calcium, it is the most widely used form of calcium in single ingredient calcium supplements as well as combination supplements. Inexpensive and an abundant source of elemental calcium, it is the only form of calcium found in nature outside of bone. It is the primary form of calcium used in the mass market and in antacid products. This is for people who have high stomach acid and who need a buffering type of calcium. Also for people who want a high dose of calcium in a minimum amount of pills. Calcium Citrate: at 21 percent elemental calcium, it is one of the most popular forms of calcium supplements in the health food market as well as the mass market. This calcium salt does not lower stomach acid as much as calcium carbonate. This calcium salt is usually recommended for people who have low stomach acid, have had stomach surgery or who need a form of calcium that will not lower their stomach acid further. Calcium Gluconate and Lactate: these two forms of calcium are high soluble. Since the amount of elemental calcium is much lower (9 percent and 13 percent respectively), they are used more often in powder form and mixed with liquids or food. When mixed in a beverage, the calcium is already dissolved and is ready to be absorbed. This is the best calcium salt for people who have overactive bowels, who have trouble swallowing pills or who don’t like the taste of pre-formed liquid calcium supplements. These calcium powders can be mixed in juices or smoothies or added to food as they are virtually tasteless. Calcium Orotate and Asporotate: In the mid 20th century, Dr. Hans Nieper, a German scientist, advanced a theory that orotic and aspartic salt forms of calcium are transported directly to cell membranes for better absorption. The Solaray brand developed an asporotate formula, which combines three organic acids: aspartic acid (-Asp), orotic acid (-oro) and citric acid (-tate) into one product. The asporotate formula has become one of the most popular calcium formulas and is exclusive to the Solaray brand. This product is for customers who appreciate the idea of combining the enhanced absorbability of three organic acids into one. Aspartate and citrate are also part of the krebs (energy) cycle and are natural to the body’s metabolic systems and, according to Neiper, calcium Orotate and Aspartate are mineral transporters that enter into the cells to facilitate enzymatic actions rather than being extra-cellular. For people who believe that intracellular calcium is of importance, calcium Orotate and asporotate may be good choice. Calcium Hydroxyapatite: this is another “natural form of calcium usually as a mineral ash form bovine source bone. Bone meal is also a form of calcium from bovine bone. These forms of animal derived calcium are for customers who want a source that is closest to their own bone matrix. Not for vegetarians. Calcium Amino Acid Chelates (*HVP): this form is calcium carbonate bonded (Chelated) to a form of amino acid complex such as whole rice concentrate or other grain source. This form is for customers who want the additional bioavailability of amino acids. Calcium AEP: Another form of calcium endorsed by Dr. Hans Nieper who theorized that calcium would cross the cell membranes more readily when it was combined with phosphatidyl ethanolamine or Amino Ethanol Phosphate (AEP), a nutrient found in nerve sheaths. This highly specialized form is for very educated customers who are proponets of Hans Niepers theory. So, which form is best? Calcium, like cars, comes in a variety of forms. Isn’t it wonderful that we have so many choices? The point is, there is no best one, there are only individual choices. Although we have our favorites, taking a calcium supplement, regardless of which one it is, should:
Our primary concern when choosing a calcium supplement should be to provide our body with the right amount of calcium daily so that our skeleton and teeth can maintain proper mineralization and strength as the cells continuously break down and rebuild. The type of calcium complex we prefer is entirely up to us. *HVP = Hydrolyzed Vegetable Protein
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1411) Remifemin symptomatic relief, scientifically supported*
Date:
August 26, 2006 02:41 PM
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Lit source: Enzymatic therapy. *this statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treate, cure, or prevent any disease.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1358) Triphala Fact Sheet
Date:
December 08, 2005 04:09 PM
Triphala Fact SheetNeil E. Levin, CCN, DANLA 6/30/05LIKELY USES: Antioxidant Colon Cleansing, Detoxifying, Digestive, Liver and bile health KEY INGREDIENTS: Triphala 500 mg, in a combination of fruit powders and extracts MAIN PRODUCT FEATURES: Triphala is a combination of three fruits (Harada, Amla, and Behada) that has been used in Ayurvedic herbalism for thousands of years. Triphala's historical use as a digestive cleanser and tonifier has been backed up with numerous modern scientific studies demonstrating the positive effects of its component herbs on the gastrointestinal tract. In addition, Triphala has been shown to be a potent antioxidant, protecting cells against the damaging effects of free radicals. May help to dispel worms. Mild-acting internal cleansing; supports liver and gastrointestinal function ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: NOW offers the first - and only - Triphala supplement to combine the fruit powders (400 mg) with the extracts (100 mg) of the fruits (doses given per tablet, there are three tablets per serving). Authorities like Dr. Andrew Weil consider Triphala to be a superior bowel tonic, rather than a laxative, with its benefits increasing over time. Laxatives typically are habit-forming and do not enhance normal body elimination of wastes; this is not the case with (moderate doses of) Triphala. This formula is suitable for vegetarians and is offered in tablet form. SERVING SIZE & HOW TO TAKE IT: As a dietary supplement, every three tablets provide 1,200 mg. (1.2 gram) Triphala powder and 300 mg. (0.30 gram) Triphala extract. Both the powder and the extract provide the three fruits in equal ratios, by weight. Take one to three servings per day, between meals. COMPLEMENTARY PRODUCTS: Fiber sources (psyllium, pectin, etc.), Detox Support, Plant Enzymes, Virgin Coconut Oil, Dr. Verghese Liver Formula, Bentonite Powder, Probiotics (GR-8 Dophilus, 4x6 Acidophilus, etc.), Electrolytes (minerals) CAUTIONS: none PRODUCT SPECIFIC: Contraindicated during pregnancy and lactation; avoid during menstruation; not appropriate for the very young or very old or the convalescent. GENERAL: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. When taking any new supplement, use common sense and cautiously increase to the full dose over time to avoid any potential problems. Packages may contain moisture or oxygen controlling packets or canisters that are not intended for consumption. In order to maintain maximum freshness, please do not remove these from your bottle (until the bottle is empty). Please recycle your container. Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. REFERENCES: Abraham S, Kumar MS, Sehgal PK, Nitish S, Jayakumar ND. Evaluation of the inhibitory effect of triphala on PMN-type matrix metalloproteinase (MMP-9). J Periodontol. 2005 Apr;76(4):497-502. PMID: 15857087 Al-Rehaily AJ, Al-Howiriny TA, Al-sohaiani MO, Rafatullah S. (2002) Gastroprotective effects of 'Amla" Emblica officinalis on in vivo test models in rats. Phytomedicine 9(6):515-522. Arora S, Kaur K, Kaur S. Indian medicinal plants as a reservoir of protective phytochemicals. Teratog Carcinog Mutagen. 2003;Suppl 1:295-300. PMID: 12616620 Jagetia GC, Baliga MS, Malagi KJ, Sethukumar Kamath M. The evaluation of the radioprotective effect of Triphala (an ayurvedic rejuvenating drug) in the mice exposed to gamma-radiation. Phytomedicine. 2002 Mar;9(2):99-108. PMID: 11995956 Jagetia GC, Malagi KJ, Baliga MS, Venkatesh P, Veruva RR (2003) Triphala, an Ayurvedic Rasayana Drug, Protects Mice Against Radiation-Induced Lethality by Free-Radical Scavenging. J Alt Complement Med 10(6):971-978. Jagetia GC, Rao Sk,, Baliga MS, Babu K (2004) The evaluation of nitric oxide scavenging activity of certain herbal formulations in vitro: a preliminary study. Phytother Res 18(7):561-565.
Kaur S, Michael H, Arora S, Harkonen PL, Kumar S. The in vitro cytotoxic and apoptotic activity of Triphala--an Indian herbal drug. J Ethnopharmacol. 2005 Feb 10;97(1):15-20. Epub 2004 Dec 25. PMID: 15652269 Kaur S, Arora S, Kaur K, Kumar S. The in vitro antimutagenic activity of Triphala--an Indian herbal drug. Food Chem Toxicol. 2002 Apr;40(4):527-34. PMID: 11893411 Sabu MC, Kuttan R (2002) Anti-diabetic activity of medicinal plants and its relationship with their antioxidant property. J Ethnopharmacol 81:155-160. Sairam K, Rao CV, Dora M, Babu K, Kumar V, Agrawal VK, Goel RK (2002) Antiulcerogenic effect of methanolic extract of Emblica Officinals: an experimental study. J Ethnopharmacol 82:1-9. Sandhya T, Lathika KM, Pandey BN, Mishra KP. Potential of traditional ayurvedic formulation, Triphala, as a novel anticancer drug. Cancer Lett. 2005 May 14; [Epub ahead of print] PMID: 15899544 Tamhane MD, Thorat SP, Rege NN, Dahanukar SA (1997) Effect of oral administration of Terminalia chebula on gastric emptying: an Experimental study. J Postgrad Med 43(1):12-13. Vani T, Rajani M, Sarkar S, and Shishoo CJ. Antioxidant Properties of the Ayurvedic Formulation Triphala and its Constituents. International Journal of Pharmacognosy Vol 35, No. 5, 1997:313-3
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=995) Vitaberry Plus + Super Fruit Antioxidant
Date:
December 07, 2005 05:43 PM
Vitaberry Plus +™ Super Fruit AntioxidantBy Nilesh Patel, NOW Quality Assurance, April 20, 2005 Why are FRUITS AND VEGETABLES important? “Diets rich in FRUITS AND VEGETABLES may reduce the risk of some types of cancer and other chronic diseases.”- National Cancer Institute. OXYGEN AND ANTIOXIDANTS As we all know, “Oxygen is critical to life,” but is itself a double-edged sword. While oxygen is necessary to sustain life and for natural defense against microbes, too much oxygen in our cells can lead to the production of “free radicals” (mitochondrial respiratory chain) or ROS (Reactive Oxygen Species). Free radicals come in many forms - singlet oxygen, hydrogen peroxide, superoxideperoxynitrite, to name a few - but all have one commonality. Each has an unpaired (unbalanced) electron, a situation it remedies by stealing an electron from a stable molecule. This sets off a domino effect of oxidation, a chain reaction that usually ends up damaging cellular integrity and compromising overall health. Nature has a defense system in place to protect these processes in the form of antioxidants. Whether endogenous (produced by the body, such as liver enzymes, SOD, coenzymes and sulfur-containing compounds) or exogenous (obtained through the diet, such as vitamins C & E, bioflavonoids, carotenes, etc.), antioxidants “quench” free radicals by donating an electron to stabilize a molecule, thus controling the chain reaction and stopping the oxidation “domino effect”. ANTIOXIDANT-RICH FOODS Research suggests that eating plenty of foods high in antioxidants helps to slow the processes associated with aging and protect against many chronic diseases. Maximizing one’s antioxidant power will enhance overall health. Fruit and vegetables contain both nutritive and non-nutritive factors that can affect oxidative damage and enzymatic defense and might contribute to redox (antioxidant and prooxidant) actions. A new “6-a-day” study looked into the effects of fruits and vegetables on markers of oxidative stress and antioxidative defense in healthy nonsmokers by The Danish Institute for Food and Veterinary Research in Denmark. The study found that fruits and vegetables increase erythrocyte glutathione peroxidase activity and resistance of plasma lipoproteins to oxidation more efficiently than do the nutritive factors (vitamins and minerals) that the fruits and vegetables are also known to contain. Certain berries, such as blackberries, also contain salicylates, which are also linked to heart health and prevention of atherosclerosis. The protective effects of fruits and vegetables intake on both heart disease death and deaths in general have previously been demonstrated but researchers at the Human Nutrition Research Center on Aging at Tufts University, Boston. Quercetin is an anti-oxidizing flavonoid found in many berries (such as cranberries, bilberries, blueberries, strawberries, etc.) and can prevent CVDs (coronary vascular diseases), according to a recent Finnish study. All these natural plant polyphenols are responsible for the colors of many red and purple berries, fruits, vegetables and flowers. GOVERNMENT GUIDELINES The new federal guidelines released earlier this year by the U.S. Department of Health and Human Services (HHS) and U.S. Department of Agriculture (USDA) recommend eating more fruits and vegetables, combined, than any other food group -- five cups or about 10 servings a day for most adults. The amount of fruits and vegetables recommended has increased for men and women of every age. “Fruits and vegetables are the "good news" story of the new Dietary Guidelines for Americans for food-loving consumers, the industry and America's public health”, stated the Produce for Better Health Foundation (PBH). Eating a variety of colorful phytochemical-rich fruits and vegetables has been associated with lower risk of some chronic diseases such as cancer and heart disease. Many authoritative organizations such as the National Cancer Institute and The American Heart Association recommend getting phytochemicals from whole foods, such as fruits and vegetables, rather than from individual component supplements. The Scottish government is promoting healthy eating through a scheme designed to increase purchasing of fruit and nutritional foods. Scottish health minister Andy Kerr said, "This initiative shows that healthy eating can be good for customers and good for business." Scottish women are said to have the highest rates of death from lung cancer in the world as well as the highest rates in Europe for coronary heart disease. They also have low consumption of fruits and vegetables, shown in studies to help protect against some cancers and benefit heart health. ROS (Reactive Oxygen Species) Free radicals and oxygen free radicals play an important role in the development and progression of many brain disorders such as brain injury, neurodegenerative disease, and Down syndrome. Oxidative stress is an important factor in the etiology and pathogenesis of diabetes & is also linked to other host of degenerative health conditions. Fortunately, antioxidants are available to support the body’s defense and fight disease and aging. Examples of “Fast acting antioxidants” in the body (serum) are: uric acid (polyphenols), ascorbate, bilirubin, vitamin E (the later two are lipid soluble). Examples of “Slow acting antioxidants” are glucose, urea nitrogen etc. In short, free radicals, reactive oxygen species (ROS) and reactive nitrogen species (RNS) are generated as by-products of normal cellular metabolism. Their deleterious effects are minimized in vivo (in the body) by the presence of antioxidant systems. How do Antioxidants work? Antioxidants are substances in plants that help maintain health. Antioxidants protect against damage to cells caused by too many “free oxygen radicals,” which form because of the effects of oxidation. Smoking, sunlight, heavy exercise, and pollution all increase oxidation in the body. Most people would benefit by eating more (five to nine or more servings) fruits and vegetables & colorful plant foods, such as purple, dark green, yellow, orange, blue, and red ones, each day. These have healthful pigments along with antioxidant nutrients such as vitamin C, carotenoids, beta-carotene, lycopene, lutein, zeaxanthin, vitamin E, selenium, flavonoids, and other beneficial substances. There are numerous ways in which these antioxidants affect, but can be explained in two groups: Alpha (a) Effects: This refers to the scavenging or neutralizing of free radicals. These effects do not change the way humans (or animals) feel. There are also no noticeable health, psychological or emotional benefits. While there are no obvious changes, increased total antioxidant intakes are associated with decreased tumor rates, prevention of heart attacks and increased longevity. Beta (ß) Effects: These are the changes on health, psychological or emotional state that you or others will notice. In this case, the antioxidant is affecting metabolic processes (enzymes) with consequent changes in the physical (improvement in joint movements, improved skin condition, tissue damage recovery), emotional (better ability to cope with stress) or psychological state (increased alertness). The ORAC value Because most of the active nutritional components in fruits and vegetables are antioxidants, accurate measurement of antioxidant activity serves as a good indicator of potential health benefit. Scientific opinion runs high that ORAC (Oxygen Radical Absorption Capacity) will eventually become a government standard of reference for overall daily fruits and vegetables intake. ORAC units are a measurement of the ability of food to stop oxidation. It is most generally expressed in terms of Trolox equivalent per gram (µmole Trolox equivalents (TE)/g). POPULATION DATA A survey done by the National Research Council indicates that only 10% of the US population consumes the recommended five servings of fruits and vegetables per day. The equivalent to eating 5 mixed servings of fruits and vegetables per day is about 1,670 ORAC units. Based on scientific evidence it is suggested that daily antioxidant intake should be increased to between 3,000 and 5,000 ORAC units per day, per human subject, in order to reach a significant antioxidant capacity in blood plasma and other tissues. WHAT IS NOW DOING TO HELP? In accord with our mission, “To provide value in products and services that empower people to lead healthier lives,” NOW® Foods is introducing an ALL-FRUIT-DERIVED antioxidant product called VitaBerry Plus +™ Super Fruit Antioxidant Vcaps (vegetarian capsules) (product number #3336). At time of manufacture this product provides an ORAC value of at least 2,500 units per serving from a full-spectrum antioxidant blend of fruits containing phytochemicals and phenolic compounds such as anthocyanins, proanthocyanins, chlorogenic acid, ellagic acid, quinic acid, resveratrol , many organic acids, resveratrol and vitamin C. VitaBerry Plus +™ is formulated with VitaBerry™ Hi-ORAC Fruit Blend [a proprietary blend of fruit extracts & concentrated powders containing Wild Blueberry (Vaccinium angustifolium) extract, Grape (Vitis vinifera) & Grape seed extract, Raspberry (Rubus idaeus) & Raspberry seed extract, Cranberry (Vaccinium macrocarpon), Prune (Prunus domestica), Tart Cherry (Prunus cerasus), Wild Bilberry (Vaccinium myrtillus) extract & Strawberry (Fragaria virginia)], Hi-Active™ Orange (Citrus sinensis) and Pomegranate (Punica granatum) min. 40% ellagic acid fruit extract. One gram of VitaBerry™ Hi-ORAC Fruit Blend provides at least 6,000 ORAC units (i.e., µmole Trolox equivalents (TE)/g). (Also watch for an upcoming antioxidant product from NOW called Enzogenol® (Pinus radiata bark extract from New Zealand) with Rutin (a flavonoid from South American fruit of Dimorphandra mollis) and Grapeseed extract. IS IT EFFECTIVE? Total ORAC value includes both lipophilic and hydrophilic components. VitaBerry Plus +™ contains only water/hydroethanol based extracts and concentrated (100:1 to 125:1) freeze-dried fresh fruit blends, so the lipophilic ORAC value is mere 2-4% of the total ORAC value. Glutathione peroxidase is a selenium-containing enzyme that decreases cell death from brain injuries. It also acts as a critical first-line antioxidant defense on the airway (respiratory) epithelial surface against ROS and RNS (reactive nitrogen species. Genetics research has found that the glutathione S-transferase gene controls the onset of Alzheimer’s, Parkinson’s disease etc. Taking glutathione (GSH) itself as a supplement does not boost cellular glutathione levels, since it breaks down in the digestive tract before it reaches the cells. So glutathione precursor dietary supplements (such as NAC and GliSODin), along with fruits and vegetables, are effective in boosting intracellular levels of GSH. The lungs have a defense system against the ROS oxidants consisting of low molecular weight antioxidants such as GSH and intracellular enzymes such as SOD, catalase and glutathione peroxidase to protect against the toxic effects of oxidants generated within the cells. Some of the primary effects of VitaBerry Plus +™ against the common reactive free-radical species or ROS are as follows: - Superoxide dismutase-SOD (destroys Superoxide radicals),- Catalase (neutralizes peroxides), - Functions similar to reduced Glutathione (GSH), - Glutathione peroxidase enzyme (detoxifies peroxides, using GSH as a reducing agent), - Functions similar to Glutathione S-transferase (GST), - Nullifies Superoxide-generating NADH/NADPH oxidase system In conclusion More concentrated than fresh berries, with over 6000 ORAC units per gram, VitaBerry Plus +™ provides consumers with the antioxidant power of almost 15 servings per day of FRUITS AND VEGETABLES ina convenient vegetarian capsule form! VitaBerry™ PLUS +™ (# 3336) provides a powerful, convenient way to supplement diets that do not include sufficient fruit and vegetable antioxidants Selected References: USDA/HHS guidelines report at: etaryguidelines/dga2005/document/
ls.com/proprietary/pdf/VitaberryBrochure.pdf g Kaplan M., Hayek T. , Raz A., Coleman R. and Aviram M. Pomegranate juice supplementation to apolipoprotein E deficient mice with extensive atherosclerosis reduces macrophages lipid peroxidation, cellular cholesterol accumulation and development of atherosclerosis. J. Nutr. 131: 2082-2089 (2001) Lars O Dragsted et. al., The 6-a-day study:effects if fruit and vegetables on markers of oxidative stress and antioxidative defense in healthy nonsmokers. American Journal of Clinical Nutrition, Vol. 79, No. 6, 1060-1072, June 2004 Fuhrman B. and Aviram M. Polyphenols and flavaonoids protects LDL against atherogenic modifications.In: Handbook of Antioxidants Biochemical, Nutritional and Clinical Aspects, 2nd Edition. Cadenas E & Packer L (Eds.) Marcel Dekker, NY(Pub.). 16:303-336 (2001) Wood, Jacqueline, et al. Antioxidant activity of procyanidin-containing plant extracts at different pHs. Food Chemistry 77 (2002) 155-161 Aviram M. Pomegranate juice as a major source for polyphenolic flavonoids and it is most potent antioxidant against LDL oxidation and atherosclerosis. Free Radical Research 36 (Supplement 1): 71-72 (2002) Jennifer Schraag, Antioxidants: Nature’s Way of Balancing Life. HSR Health Supplement Retailer, Vol. 11, No. 2, 24-27, February 2005 com/news/printNewsBis.asp?id=58665 com/news/printNewsBis.asp?id=58697
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=992) TMG Fact Sheet
Date:
December 07, 2005 02:13 PM
TMG Fact SheetNeil E. Levin, CCN, DANLA 03/07/05LIKELY USERS: People with high homocysteine levels; People with risks of developing Alzheimer’s Disease; People needing greater metabolism of fats; People with liver detoxification challenges; People consuming alcohol KEY INGREDIENTS: TMG is composed of three methyl groups attached to a glycine atom. It can “donate” methyl groups. MAIN PRODUCT FEATURES: TMG is a metabolite of the B vitamin family product called Choline. Choline has 4 methyl groups, TMG has 3 and DMG has 2. These substances plus Folic acid, Vitamin B-12 and SAM-e are all methyl donors. Methyl donors can contribute methyl groups to biological processes such as liver function, detoxification and cellular replication (production of new cells). Methylation protects the kidneys and stimulates production of the fat-transporting molecule l-carnitine. TMG helps the liver metabolize fats, preventing the accumulation of fats in the liver. It also helps to detoxify chemicals in the liver, while protecting the liver from being damaged by those chemicals. Methylation with TMG helps to convert the dangerous, inflammatory chemical homocysteine into the amino acid methionine. TMG may lower homocysteine when B-6, B-12 and folic acid cannot. ADDITIONAL PRODUCT INFORMATION: TMG is also known as Betaine and is a component of Betaine hydrochloride (Betaine HCl), a stomach acid supplement that is very acidic. But Betaine HCl is not used in the same way as TMG. TMG is not highly acidic and will not supplement low stomach acid. TMG may be useful for autistic children, along with B-6 and magnesium. It may also be useful in strengthening the body’s immune response against pathogenic bacteria. There is very preliminary evidence that TMG and methyl donors may help against some forms of seizures. DMG has been used as a sports supplement. TMG is 50% more effective than DMG in any application where the methyl groups are useful. Otherwise, they can used interchangeably. SERVING SIZE & HOW TO TAKE IT: One serving per day, or up to 6,000 mg., as needed. COMPLEMENTARY PRODUCTS: SAM-e, Milk Thistle (Silymarin), Dr. Verghese’s Liver Detoxifier & Regenerator, Antioxidants, NAC, Homocysteine Regulators, D-Flame, Detox Support CAUTIONS: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. People with Parkinson’s or taking L-dopa should not use methyl donors like TMG without a physician’s specific approval and supervision. There are no other known drug interactions with TMG. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. This is not an official publication by any company, nor has this information been screened or approved by the FDA or any private company. Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. REFERENCES: General: Craig SA. Betaine in human nutrition. Am J Clin Nutr. 2004 Sep;80(3):539-49. Review. PMID: 15321791 Methylation: Barak AJ, Tuma DJ. Betaine, metabolic by-product or vital methylating agent? Life Sci 1983;32:771-4 [review]. Benson R, Crowell B, Hill B, et al. The effects of L-dopa on the activity of methionine adenosyltransferase: relevance to L-dopa therapy and tolerance. Neurochem Res 1993;18:325–30. Chambers ST. Betaines: their significance for bacteria and the renal tract. Clin Sci 1995;88:25-7 [review]. Charlton CG, Crowell B Jr. Parkinson’s disease-like effects of S-adenosyl-L-methionine: effects of L-dopa. Pharmacol Biochem Behav 1992;43:423–31. Charlton CG, Mack J. Substantia nigra degeneration and tyrosine hydroxylase depletion caused by excess S-adenosylmethionine in the rat brain. Support for an excess methylation hypothesis for parkinsonism. Mol Neurobiol 1994;9:149–61. Cheng H, Gomes-Trolin C, Aquilonius SM, et al. Levels of L-methionine S-adenosyltransferase activity in erythrocytes and concentrations of S-adenosylmethionine and S-adenosylhomocysteine in whole blood of patients with Parkinson’s disease. Exp Neurol 1997;145:580–5. Crowell BG Jr, Benson R, Shockley D, Charlton CG. S-adenosyl-L-methionine decreases motor activity in the rat: similarity to Parkinson’s disease-like symptoms. Behav Neural Biol 1993;59:186–93. Selhub J. Homocysteine metabolism. Annu Rev Nutr 1999;19:217-46 [review]. Homocysteine: Brosnan JT, Jacobs RL, Stead LM, Brosnan ME. Methylation demand: a key determinant of homocysteine metabolism. Acta Biochim Pol. 2004;51(2):405-13. Review. PMID: 15218538 Gahl WA, Bernardini I, Chen S, et al. The effect of oral betaine on vertebral body bone density in pyridoxine-non-responsive homocystinuria. J Inherit Metab Dis 1988;11:291-8. Olthof MR, van Vliet T, Boelsma E, Verhoef P. Low dose betaine supplementation leads to immediate and long term lowering of plasma homocysteine in healthy men and women. J Nutr. 2003 Dec;133(12):4135-8. PMID: 14652361 Olthof MR, Verhoef P. Effects of betaine intake on plasma homocysteine concentrations and consequences for health. Curr Drug Metab. 2005 Feb;6(1):15-22. PMID: 15720203 Schwab U, Torronen A, Toppinen L, Alfthan G, Saarinen M, Aro A, Uusitupa M. Betaine supplementation decreases plasma homocysteine concentrations but does not affect body weight, body composition, or resting energy expenditure in human subjects. Am J Clin Nutr. 2002 Nov;76(5):961-7. PMID: 12399266 Selhub J. Homocysteine metabolism. Annu Rev Nutr 1999;19:217-46 [review]. van Guldener C, Janssen MJ, de Meer K, et al. Effect of folic acid and betaine on fasting and postmethionine-loading plasma homocysteine and methionine levels in chronic haemodialysis patients. J Intern Med 1999;245:175-83. Wendel U, Bremer HJ. Betaine in the treatment of homocystinuria due to 5,10-methylenetetrahydrofolate reductase deficiency. Eur J Pediatr 1984;142:147-50. Wilcken DE, Wilcken B, Dudman NP, Tyrrell PA. Homocystinuria—the effects of betaine in the treatment of patients not responsive to pyridoxine. N Engl J Med 1983;309:448-53. Wilcken DE, Dudman NP, Tyrrell PA. Homocystinuria due to cystathionine beta-synthase deficiency--the effects of betaine treatment in pyridoxine-responsive patients. Metabolism. 1985 Dec;34(12):1115-21. PMID: 3934499 Liver function: Babucke G, Sarre B. Clinical experience with betain citrate. Med Klin 1973;68:1109-13 [in German]. Barak AJ, Beckenhauer HC, Badakhsh S, Tuma DJ. The effect of betaine in reversing alcoholic steatosis. Alcohol Clin Exp Res 1997;21:1100-2. Barak AJ, Beckenhauer HC, Matti J, Tuma DJ. Dietary betaine promotes generation of hepatic S-adenosylmethioine and protects the liver from ethanol-induced fatty infiltration. Alcohol Clin Exp Res 1993;17:552-5. Barak AJ, Beckenhauer HC, Tuma DJ. Betaine, ethanol, and the liver: a review. Alcohol 1996;13:395-8 [review]. PMID: 8836329 Freed WJ. Prevention of strychnine-induced seizures and death by the N-methylated glycine derivatives betaine, dimethylglycine and sarcosine. Pharmacol Biochem Behav. 1985 Apr;22(4):641-3. PMID: 2581277 Junnila M, Barak AJ, Beckenhauer HC, Rahko T. Betaine reduces hepatic lipidosis induced by carbon tetrachloride in Sprague-Dawley rats. Vet Hum Toxicol 1998;40:263-6. Ji C, Kaplowitz N. Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice. Gastroenterology. 2003 May;124(5):1488-99. PMID: 12730887 Kettunen H, Tiihonen K, Peuranen S, Saarinen MT, Remus JC. Dietary betaine accumulates in the liver and intestinal tissue and stabilizes the intestinal epithelial structure in healthy and coccidia-infected broiler chicks. Comp Biochem Physiol A Mol Integr Physiol. 2001 Nov;130(4):759-69. PMID: 11691612 Kim SK, Kim YC, Kim YC. Effects of singly administered betaine on hepatotoxicity of chloroform in mice. Food Chem Toxicol 1998;36:655-61. McCarty MF. Co-administration of equimolar doses of betaine may alleviate the hepatotoxic risk associated with niacin therapy. Med Hypotheses. 2000 Sep;55(3):189-94. PMID: 10985907 Murakami T, Nagamura Y, Hirano K. The recovering effect of betaine on carbon tetrachloride-induced liver injury. J Nutr Sci Vitaminol 1998;44:249-55. Poschl G, Stickel F, Wang XD, Seitz HK. Alcohol and cancer: genetic and nutritional aspects. Proc Nutr Soc. 2004 Feb;63(1):65-71. Review. PMID: 15070439 Semmler F. Treatment of liver diseases, especially of fatty liver with betaine citrate. Ther Ggw 1977;116:2113-24 [in German]. Zapadniuk VI, Panteleimonova TN. [Cholagogic effect of trimethylglycine in normal animals of different ages and in experimental atherosclerosis] Biull Eksp Biol Med. 1987 Jul;104(7):30-2. Russian. PMID: 3620644 Autism & Seizures: Rimland B. Seizures, Vitamin B6, DMG, and Sudden Speech. Autism Research Review International. 1996;10(2):1. Roach ES, Carlin L. N,N-dimethylglycine for epilepsy. N Engl J Med. 1982;307:1081-82. Vitamin B6/DMG. Letters to the Editor, Autism Research Interview International. 1994;8(2):6. Immunity: Reap EA, Lawson JW. Stimulation of the immune response by dimethylglycine, a nontoxic metabolite. J Lab Clin Med. Apr1990;115(4):481-6. Safety: Hoorn AJ. Dimethylglycine and chemically related amines tested for mutagenicity under potential nitrosation conditions. Mutat Res. 1989 Apr;222(4):343-50. PMID: 2468082
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=988) PepZin GI™ helps relieve occasional discomfort.
Date:
September 20, 2005 05:40 PM
PepZin GI™ helps relieve occasional discomfort.* CLINICAL TRIALS In a randomized, multi-center, placebo-controlled double blind study, 299 patients suffering with symptoms of gastric discomfort were randomly allocated to receive either a zinc-L-carnosine complex or a placebo, or a control drug or its placebo for 8 weeks. Improvement ratings for a range of symptoms were taken at various points during the trial and compared with before treatment data. Of the 258 people who completed the trial, 136 were in the zinc-Lcarnosine group. Of the group, 92% of the participants were rated as “moderately improved” or better on an improvement scale across the category of symptoms including heartburn, tenderness, epigastric pain, diarrhea and constipation after 8 weeks.3 In another study, 28 patients with gastric discomfort were given a zinc-L-carnosine compound and monitored for 8 weeks. Improvement was rated on a scale of subjective and objective symptoms. After 4 weeks, the rate of those cases that were considered to be “significantly improved” was 68.4%. After eight weeks, the “significantly improved” number was 68.8%. Over 60% of these patients remained in the “significantly improved” category well after discontinuation of the treatment, suggesting a lasting effect of the zinc-L-carnosine compound beyond the time it is taken.4 Maintains a healthy GI environment.* The mineral zinc in PepZin GI™ is a critical component to a number of physiological processes in our bodies. Some of these functions include growth and metabolism of cells, healing of wounds,and maintenance of carbohydrate and lipid metabolism.2 PepZin GI™ may also be able to favorably maintain the bacterial balance of the stomach and GI tract. Studies suggest that the zinc-L-carnosine co m pound may have effects on certain strains of harmful bacteria and, therefore, may be able to help maintain a GI environment that is favorable to health.1 By supporting the bacterial balance in the stomach, PepZin GI™ can help maintain a healthy mucosal lining. Supports the health of gastric cells.* PepZin GI™ has been studied for its ability to prevent free radical damage to gastric cells. In one such study, rat gastric cells were exposed to ethanol and hydrogen peroxide, two substances known to cause free radical damage to living cells. Cells were bathed in hydrogen peroxide, ethanol, zinc-L-carnosine, or a combination of zinc-L-carnosine with either ethanol or hydrogen peroxide. While the cells bathed in ethanol and hydrogen peroxide solutions all exhibited signs of damage due to free radical production, the cells that were bathed in zinc-L-carnosine were largely protected from the effects of free radical damage. The authors concluded that the zinc compound directly protected gastric mucosal cells from oxidant stress and alcohol induced damage.5 Additional research further confirms the gastro-protective effects of PepZin GI™. In another rat study, stomach lesions were induced by administration of the chemical monochloramine, a known pro-oxidant (producer of free radicals). One of the groups of rats was fed the zinc-Lcarnosine compound prior to being exposed to monochloramine. The researchers found that the size of the lesions in the group pre-treated with zinc-L-carnosine was significantly less than the lesions in the control group. The authors concluded that the zinc compound exerted a beneficial protective effect against monochloramine-induced stomach lesions.6 The zinc-L-carnosine in PepZin GI™ has also been shown to slow the development of aspirin induced stomach damage in rats. The researchers measurably detected lower levels of TNF-alpha in rats given zinc-L-carnosine as compared to the control rats. TNF-alpha is an inflammatory cytokine that is known to be released in response to gastric damage.7 These results may suggest a role for PepZin GI™ in protecting gastric cells by occasionally reducing the levels of certain cytokines in minor inflammation of the stomach. Scientific References 1. Kuwayama H, et al. Polaprezinc. Nippon Rinsho 2002 Feb; 60 Suppl 2:717-720. 2.Matsukura T,Tanaka H. Applicability of zinc complex of l-carnosine for medical use. Biochemistry (Moscow) 2000;65(7):817-823. 3.Miyoshi A, et al. Clinical evaluation of Z-103 on gastric ulcer - a multicenter double-blind comparative study with cetraxate hydrochloride. Jpn PharmTher 1992;20(1):199-223. 4.Misawa T, et al. Clinical study of Z-103 - clinical effects on gastric ulcer and influence on endocrine function. Jpn PharmTher 1992; 20(1):245-254. 5. Hiraishi H, et al. Polaprezinc protects gastric mucosal cells from noxious agents through antioxidant properties in vitro. Aliment Pharmacl Ther 1999;13:261-269. 6. Kato S, Nishiwaki H, et al. Mucosal ulcerogenic action of monochloramine in rat stomachs: effects of polaprezinc and sucralfate. Dig Dis Sci 1997;42(10):2156-2163. 7.Naito Y, et al. Effects of polaprezinc on lipid peroxidation, neutrophil accumulation, and TNF-alpha expression in rats with aspirin-induced gastric mucosal injury. Dig Dis Sci 2001;46(4):845-851.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=792) Curcumin - Turmeric Extract
Date:
August 19, 2005 12:47 PM
Turmeric- History and Traditional Usage
Native to Southeast Asia, Curcuma longa is a tall
In addition to its
Turmeric is named in
Protects cells and tissues by fighting free radicals.* Supports joint function*
The numerous beneficial
Curcumin demonstrates Animal studies- In vivo protective effects
Through its free radical scavenging Human Trials
Curcumin exhibits free-radical scavenging ability when
Bioperine-Nature’s Absorption Enhancer
Traditional Ayurvedic herbal
Curcumin is poorly absorbed in the intestinal Scientific References
© 2002 *This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=734) THE FDA AND NON-CALORIC SWEETENERS
Date:
July 15, 2005 12:27 PM
THE FDA AND NON-CALORIC SWEETENERS While white sugar, turbinado, fructose, honey and corn syrup all qualify as natural sweeteners, none of these are calorie- free nor can they be used by people who suffer from blood sugar disorders. They can encourage weight gain, tooth decay, raise blood sugar quickly, and can also predispose certain individuals to yeast infections. These sugars can also contribute to indigestion, bowel disorders and, possibly, hyperactivity or ADD in children. Pharmaceutical sweeteners like aspartame and saccharin qualify as calorie-free but come with significant limitations and health risks. Saccharin has been labeled with a warning that it has caused the development of cancer in laboratory animals but is still available for purchase. In 1970, cyclamates, another class of artificial sweeteners, were banned because of the strong possibility that they are, in fact, carcinogenic. Aspartame has been marketed as a safe substance for the general public, except for those few individuals who suffer from PKU (phenylketonuria), a relatively rare disorder. Most consumers assume that aspartame is a perfectly benign compound and use it liberally. It is, in fact, comprised of phenylalanine, aspartic acid, and methanol (wood alcohol). As previously mentioned, various side effects have been associated with the ingestion of aspartame and include migraines, memory loss, slurred speech, dizziness, stomach pain, and even seizures. In addition, because aspartame contains chemicals which affect brain cell function, significant questions have been raised concerning its link to increased incidence of brain tumors (Olney). Acesulfame K, another artificial sweetener on the market, has also been linked to cancer by the Center for Science in the Public Interest. Despite the protest of various organizations and health professionals, these pharmaceutical s weeteners have been approved by the FDA and are recognized as safe.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=641) ARTIFICIAL SWEETENERS: CAUSE FOR WORRY
Date:
July 15, 2005 12:26 PM
ARTIFICIAL SWEETENERS: CAUSE FOR WORRY Among some of the most troubling food additives that we routinely ingest are artificial sweeteners, also referred to as non-nutritive sweeteners. Having received the FDA stamp of approval, they are liberally ingested with little thought to what their actual health risks may be. Andrew Weil, M.D., in his book Natural Health Natural Medicine, writes: More worrisome than preservatives are artificial sweeteners. Saccharin, a known carcinogen, should be avoided. Cyclamates, banned some years ago for suspected carcinogenicity, are not being reconsidered for use in food. They taste better than saccharin but cause diarrhea in some people. Avoid them too. Recently, aspartame (NutraSweet) has become enormously popular. The manufacturer portrays it as a gift from nature, but, although the two component amino acids occur in nature, aspartame itself does not. Like all artificial sweeteners, aspartame has a peculiar taste. Because I have seen a number of patients, mostly women, who report headaches from this substance, I don’t regard it as free from toxicity. Women also find that aspartame aggravates PMS (premenstrual syndrome). I think you are better off using moderate amounts of sugar than consuming any artificial sweeteners on a regular basis. A natural sweetener that may cause some people problems is sorbitol, originally derived from the berries of the mountain ash tree. Sorbitol tastes sweet but is not easily absorbed form the gastrointestinal tract and is not easily metabolized. It is a common ingredient of sugarless chewing gums and candies. If you eat a lot of it, you will probably get diarrhea. People with irritable bowel syndrome or ulcerative colitis should avoid sorbitol. Ann Louise Gittleman, in her book, Super Nutrition for Women, writes: In 1977, a Canadian study indicated that when pregnant rats were fed large doses of saccharin, their male offspring developed bladder cancer. As a result, the Canadians banned saccharin and the U.S. Congress ordered warning labels on all saccharin products like Sweet ‘N Low. The national Academy of Sciences in 1978 evaluated the evidence and concluded that saccharin was primarily a promoter of other cancer-causing agents, a cocarcinogen. In the meantime, G.D. Searle developed aspartame, a combination of two amino acids and methanol (wood alcohol) . . . Few long-term studies of the effects of aspartame have been done. However, reports to the Food and Drug Administration and the Centers for Disease Control indicate that, as more people consume the substitute in large quantities, health may be affected. In some circumstances, individuals may be getting high levels of methanol; for example, it is estimated that on a hot day after exercise, an individual drinking three 12-ounce cans of diet cola could easily consume as much as eight times the Environmental Protection Agency’s recommended limit for methanol consumption. The most common complaints are dizziness, disorientation, tunnel vision, ear buzzing, loss of equilibrium, numbing of hands and feet, inflammation of the pancreas, high blood pressure, eye hemorrhages and seizures. Artificial sweeteners can stimulate hunger or cause additive allergies, just as sugar does. In other words, we get the disadvantages of sugar, along with the proven or suspected disadvantages of artificial sweeteners. While thousands of Americans continue to consume aspartame in unprecedented amounts, controversy surrounding its safety lingers. Dr. Richard Wurtman of the Massachusetts Institute of Technology (MIT) has reported that abnormal concentrations of neurotransmitters developed when he fed laboratory animals large doses of aspartame. He believes that the phenylalanine content of the sweetener actually manipulates and alters certain brain chemicals which could initiate behavioral changes and even seizures. He also purports that while small quantities of aspartame may be safe, the cumulative effects of the compound—particularly if consumed with high carbohydrate, low protein snacks—could be serious (Wurtman I, 799-801, Wurtman II, 429-430, Wurtman III, 1060). In spite of serious concerns, saccharine and aspartame packets sit in restaurant sugar bowls all over our country, while in Japan, natural stevia powder enjoys popularity as one of the best and safest non-caloric sweeteners available.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=640) References
Date:
July 12, 2005 10:28 AM
References
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=597) Ginkgo: A Hair Tonic t hat Lowers Cholesterol Levels?
Date:
June 25, 2005 12:04 PM
Ginkgo: A Hair Tonic t hat Lowers Cholesterol Levels? Japanese experiments have recently found that the ethanolic extract found in ginkgo leaves demonstrated the ability to stimulate hair re g rowth in mice which had been given a normal and a high butter diet. Test results found that ginkgo extract not only inhibited the increase of serum triglyceride levels in the mice who ate a highly saturated diet, it also significantly promoted the growth of hair in shaved areas.13 When ginkgo is combined with garlic, a considerable drop in cholesterol levels is also observed. A number of patients with elevated cholesterol levels showed an improvement rate of 35 percent versus a control group.14 The secret to keeping cholesterol leve l s consistently low is long-term therapy with garlic and ginkgo. When the extracts were no longer taken, cholesterol levels began to rise again.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=463) Higher Mind - Smart Nutrients for the Performance of a Lifetime...
Date:
June 02, 2005 12:18 PM
Our adult years are the time to reap the fruit of an active, meaningful life – appreciated by family and friends who value our experience and knowledge. For some, however, their later years are clouded by a mental decline that erodes their capacity to enjoy life. More of us are becoming apprehensive about the future health of our minds. Will we still be able to communicate our needs as well as our wisdom? As science focuses its investigative might on the workings of the human brain, new findings suggest that it is possible to enjoy a vital, healthy brain and mind – well into old age. Based on compelling research, Source Naturals formulated HIGHER MIND. It contains the most important Neuroceuticals™ now recognized by nutrition scientists – including phosphatidyl serine, a natural nutrient that promotes cognitive function. The connection is clear: nourish your brain; enrich your life. To have a healthy, well-functioning brain and nervous system, we need the correct nutrients. Our diets must provide the necessary raw materials for nerve cells to grow, for the synthesis of neurochemicals, and for the maintenance of nerve cell membranes. Nutritional deficiencies can alter the brain’s metabolism, which is expressed by changes in perception and thinking, behavior and mood. Brain Cells – Issued at Birth Before birth, neurons (nerve cells) are created at the amazing rate of 15 million per hour. As infants, we have over 100 billion neurons, but this is the most we will ever have because – unlike most other cells in our body – nerve cells do not reproduce. A different strategy is used to replace the neurons that are naturally lost throughout life: nerve cells repair themselves and grow by extending branches of nerve fibers called dendrites (from the Latin word for tree). These are the communication links with other neurons that form the circuitry of the brain. A single neuron may be in contact with up to a hundred thousand others! When the density of this fragile organic communication network decreases, we experience a corresponding decline in mental acuity. Brain Cell Membranes The membrane is the working surface of a cell. It needs to be strong yet flexible, so the cell can maintain its integrity and be able to move and change shape. The membrane regulates the flow of nutrients into the cell and the removal of waste, plus controls the passage of molecular messages from outside the cell to its interior. Membrane ion pumps use a third of the cell’s energy just to maintain the correct ratio of sodium to potassium. In neurons, a rapid exchange of sodium and potassium ions across the nerve membrane is responsible for their unique ability to generate the electrical impulses that are the basis of all communication in the nervous system. As cells age, their membranes become less fluid and more rigid. Key membrane molecules called phospholipids are crucial to the health of neuron membranes, allowing the brain to maintain its youthful quality. The phospholipids in HIGHER MIND – especially phosphatidyl serine and phosphatidyl choline – are essential nutritional supplements for the aging brain. Phosphatidyl Serine – Key to Cognition For the past decade, researchers have been investigating the role in brain health of a remarkable neuroceutical, phosphatidyl serine (PS). This key structural molecule is integral to the matrix of fats and proteins that compose cell membranes. Although PS is found in all the cells of the body, its highest concentration is in nerve cell membranes. PS is rarely found in the foods we eat, so the body has to synthesize it, but the process is energy- intensive and becomes less efficient with age. Consequently, our levels of PS tend to decline as we get older. PS taken as a dietary supplement is well-absorbed, readily reaching the brain, where it helps create more effective, well-structured nerve cell membranes. The positive effects of PS supplementation have been demonstrated by 23 clinical studies with over 1200 human subjects, ages 43 to 90. Consistent and statistically significant results have confirmed the value of PS in improving age-related cognitive decline, as well as in improving behavioral aspects such as apathy and withdrawal.1 A major study concluded that for one particular measurable parameter of higher mental functions, PS recipients achieved scores of persons roughly 12 years younger.2 Nerve Growth Factor (NGF) is one of the most important proteins the body makes. It enables neurons to extend dendrites out to other neurons, allowing the brain to maintain an effective communication network. In experiments, PS enhanced the production and reception of NGF, which tend to drop off radically with age.3 The effects of PS at the cellular level are manifest in the performance of the brain as a whole. Subjects taking PS showed increased levels of brain energy metabolism. This enhancement corresponded to higher performances on cognitive tests.4 The Chemistry of Thought Science now understands the role of neurotransmitters in regulating the body’s complex network of behavior. Neurotransmitters are the chemicals used by neurons to communicate with each other. Activated by a neuron’s electrical impulse, neurotransmitters travel between nerve cells, where they excite or inhibit (in various degrees) the electrical impulse in neighboring cells. One of HIGHER MIND’S key strategies is to improve the brain’s ability to produce and use acetylcholine, a key excitatory neurotransmitter. Acetylcholine is essential for both the storage and recall of memory, and partly responsible for concentration and focus. It also plays a significant role in muscular coordination. Patients showing cognitive decline may exhibit reduced ability to synthesize and utilize acetylcholine.5 The chemical building blocks of acetylcholine and other neurotransmitters are called precursors. The most important one for acetylcholine is DMAE (dimethylaminoethanol). This natural substance is found in various fish, such as anchovies and sardines. Supplements of DMAE (and phosphatidyl choline) promote increased levels of choline in the brain. Acetylcholine is created when an acetyl group is attached to the choline molecule, with the help of choline acetyl transferase (CAT), a key brain enzyme. Acetyl L-carnitine is an amino acid that activates this enzyme. Acetyl L-carnitine may also help reduce lipofuscin deposits in the brain because of its involvement in the metabolism of fatty acids.6 Lipofuscin is composed of oxidized fats and proteins; the brown “age spots” on the back of an elderly person’s hand are made of lipofuscin. The amino acid L-pyroglutamic acid sensitizes the acetylcholine receptor sites on a neuron membrane. A given amount of acetylcholine will then have a larger, more powerful effect. Studies have shown that supplements of L-pyroglutamic acid seem to enhance the ability to focus, remember, and learn. Total Nutrition for the Brain The neurotransmitters dopamine and noradrenalin are critical to motor coordination, motivation, concentration, and alertness. Like acetylcholine, their production tends to decline with age. The precursors and activators of dopamine and noradrenalin included in HIGHER MIND are the amino acids N-Acetyl L-Tyrosine and DL-phenylalanine (DLPA), plus folic acid, vitamins B-3, B-6, and C. DLPA is also a precursor to PEA, a neuroamine that has a stimulating effect on the brain. Glutamine is an amino acid precursor to glutamic acid, a major excitatory neurotransmitter involved in mental activity and learning. Glutamine acts as an alternative fuel source for the brain when blood sugar levels are low. It also helps the brain dispose of waste ammonia, which is a natural result of protein breakdown but is irritating to neurons even at low levels. GABA is a dietary amino acid which is also an inhibitory neurotransmitter. GABA works to calm and balance the mind, enhancing mental focus. Along with taurine, these two relaxing neurotransmitters provide a balancing influence to the other, excitatory neurotransmitters. Taurine is found in brain tissue more than anywhere else in the body. It has antioxidant properties and serves as a nerve cell membrane stabilizer, preventing excessive or erratic electrical activity in the brain. The Importance of Magnesium Magnesium must be present in adequate amounts in the synaptic gaps between neurons or the neurons become hyper-reactive: causing noises to sound excessively loud and emotional reactions to be extreme. Magnesium also activates a key enzyme responsible for maintaining cellular sodium- potassium balance, which is absolutely essential to the electrical activity of nerve cells, as well as to the existence of the cell itself. (Cells would burst if the sodium-potassium ratio were wrong.) Magnesium also helps relax cerebral blood vessels and is important to the manufacture of ATP, the chief energy molecule of the brain. A buildup of aluminum has been found in the brains of some elderly. In 1989, the British medical journal Lancet published a study showing that drinking water with aluminum can increase the risk of damage by up to 50%. An abundant natural element, aluminum is now a common feature in our culture. It’s found in tap water, cookware, deodorants, beverage containers, baked goods, and of course as aluminum foil. In the brain, aluminum breaks down the structure of neurons – causing them to starve – by displacing magnesium from tubulin, a glycoprotein responsible for making microtubules. These tiny pipe-like structures within a neuron provide needed rigidity, as well as transport nutrients from the nucleus down the dendrites to the ends of the nerve cell. Magnesium malate is an excellent form of magnesium that ensures neurons receive this vital mineral. B is for Brain Vitamins HIGHER MIND also contains a high profile of B vitamins and other key nutrients that are often N A T U R A L S S O U R C E Strategies for Wellness SM ¤ lacking in older individuals. A deficiency in any of the B vitamins can alter nerve function and psychological well-being. Thiamine (B-1), known as the “nerve vitamin,” was first recognized because its deficiency caused beriberi, a degenerative nerve disease. Thiamine is part of the structure of nerve cell membranes and is important to the reparative process that neurons need to offset the stress of continual firing of the electrical impulse. Low amounts of thiamine can cause cell malnutrition in the hypothalamus, the brain’s memory center. 7 NAD and NADH, two coenzyme forms of Niacin (B-3), are the most plentiful coenzymes in the brain. They are essential to hundreds of enzymatic reactions, including ones that produce energy. NADH can stimulate the synthesis of key mood-elevating neurotransmitters. It is also one of the body’s most potent antioxidants. Pantothenic acid (B-5), cyanocobalamin (B-12), and folic acid are required to form the myelin sheath – the insulating covering of nerve fibers. A diet low in pantothenic acid has been shown to make test subjects emotionally upset, irritable, and depressed.7 A lack of B-12 can result in poor concentration and, in severe deficiencies, hallucinations. Pyridoxine (B-6) is precursor to over 60 enzymatic reactions and is involved in the synthesis of several neurotransmitters. Brain Power Brain cells almost exclusively burn glucose for their energy (other cells can also burn fat), and typically require 50% of all the glucose in the blood. Two B-like vitamins help in the utilization of glucose: PAK (pyridoxine alpha-ketoglutarate) may potentiate the effects of insulin and improve glucose utilization to the cells;8 Biotin is important for the transformation of glucose into energy in the brain. Lipoic acid and coenzyme Q10 are metabolic energizers that help produce ATP, the primary energy molecule in the body. Since the brain uses 20% of the body’s total energy supply, efficient ATP production is vital. Lipoic acid and CoQ10 are also powerful antioxidants that help regenerate other antioxidants in the body. The blood vessels feeding the brain become less efficient as we pass middle age. Since the brain depends on the bloodstream to deliver nutrients and oxygen and to remove waste, the quality of this blood flow is paramount to proper brain nutrition. Ginkgo biloba leaf extract has been shown in scientific studies to increase blood flow to the brain by helping vessels to dilate. It also promotes the smoothness and healthy integrity of blood vessel linings. For the Life of Your Mind Without proper nutrition, the brain will deteriorate; therefore strategies are needed to both enhance current brain function and protect it throughout life. Based on the latest scientific findings, Source Naturals HIGHER MIND is formulated with neuroceuticals that support the mental functions that tend to decline with age. They give your brain the nourishment it needs to integrate perception, memory, and learning into a more comprehensive awareness – so you can excel for a lifetime.
References
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=156) Hangover Formula - Fight Hangovers with this formula...
Date:
June 02, 2005 11:37 AM
Whether you plan to “tie one on” during a holiday, or just sip a little wine with dinner, you should be aware that you may experience a form of low-level toxicity. When you drink, your body converts alcohol into toxic by-products, especially one called acetaldehyde. These toxins cause free radical damage and other problems, and are to blame for the hangover experience. HANGOVER FORMULA from Source Naturals may help to prevent and relieve some of the causes of hangovers. Its potent combination of antioxidants and Western and Chinese herbs is designed to help neutralize the negative effects of alcohol and replenish the nutrients it destroys. Fight Free Radicals Acetaldehyde causes the creation of free radicals, which can disrupt cellular activities throughout your body. This causes damage that accumulates with continued use, and is particularly threatening in its effect on the liver. But research shows that Vitamins C and E, and the amino acid Cysteine, act as an antioxidant force to counter the acetaldehyde-produced free radicals, helping to protect against long-term damage. HANGOVER FORMULA provides substantial amounts of these nutrients, and includes Cysteine both in its free form and as the powerful N-Acetyl Cysteine. Help Counteract the Energy Drain Acetaldehyde also poisons the energy-generating processes in our cells, the Krebs and glycolytic cycles. It breaks down the protein fraction of enzymes needed to keep these energy generation cycles going. It also damages enzymes that help carry nutrients through the intestinal walls, and others used by the liver to activate vitamins so they can be used in the body. This destruction of critical enzyme systems causes the intense fatigue and the feeling of literally being poisoned that are associated with hangovers and with too much drink, too fast. HANGOVER FORMULA provides the vitamins and minerals necessary to replace the damaged enzymes and keep the Krebs and glycolytic energy cycles going. The result? You feel better — stronger and healthier — than you might otherwise. Guard Against Severe Depletion of Critical Vitamins and Minerals Alcohol impairs absorption of a wide range of essential vitamins and minerals by the intestines. Many of the vitamins at particular risk are BVitamins such as B1, or Thiamine. Alcohol also disrupts the kidneys’ ability to conserve the mineral Magnesium, which is then flushed out in the urine. To help reduce the risk of severe depletion, HANGOVER FORMULA provides two of the principal minerals related to nerve function — Calcium and Magnesium — plus substantial amounts of all the B-Vitamins, with an especially high level of Thiamine. The Acetylcholine Connection Another major effect of alcohol in the body is the destruction of acetylcholine, one of the body’s most important neurotransmitters. HANGOVER FORMULA includes Phosphatidyl Choline, Choline Bitartrate, and DMAE (dimethylaminoethanol), which are precursors for acetylcholine. Alcohol also causes the brain’s sensitive cell membranes to get very “puffy” (or “fluidized” in scientific terms). This is followed by a rebound effect, and thecell membranes get too “thin,” which can result in a lack of coordination and focus. The acetylcholine precursors in HANGOVER FORMULA also help restore the normal levels of fluidity to these cell membranes, and assist in clearing and focusing the mind again. Herbal Approaches Naturopaths worldwide address hangovers with cleansing herbs that help the body regain its natural balance. HANGOVER FORMULA employs a sophisticated selection of these powerful herbs. Chinese Herbology contributes Pueraria Flowers (Ko Hua), specifically to cleanse; Magnolia Bark (Hou Pu), to relieve food stagnation; and Gastrodiae Root (Tien Ma), to relieve tension and excessive “liver yang.” Western Herbology provides Gravel Root, Slippery Elm, and Peach Leaves to restore fluid balance, plus Fennel Seeds, Cloves, and Mint to enhance assimilation. Other herbs of benefit include Germinated Rice, Crysanthemum Flowers, Marshmallow Root, and most importantly, Feverfew Leaf and Milk Thistle Seeds. Numerous studies in the scientific publication Lancet have demonstrated the amazing efficacy of the Feverfew Leaf. This traditional herbal remedy apparently helps to block the effects of hormone-like biochemicals called leukotrienes, which — when out of control — cause intense discomfort, until the body can once again get in balance. Three tablets of HANGOVER FORMULA provides 100 mg of a very potent Feverfew Extract. Silymarin, an extract of Milk Thistle Seeds, is the most popular herb in Germany for the liver. It helps keep this major cleansing organ in optimal working order by fighting free radicals and thus minimizing damage. In addition, Silymarin enhances the unique self-regenerative properties of the liver by helping accelerate repair when damage has been done. Complete Nutritional & Herbal Support To counter nutrient depletion and ease discomfort during hangover miseries, HANGOVER FORMULA is here to help.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=153) Kudzu - Herbs with alcohol intake suppressive agents ...
Date:
May 25, 2005 09:25 AM
Kudzu and the discovery of daidzin and its anti-dipsotropic activity
Definition:
D A I D Z I N : A PO T E N T I A L A G E N T FO R T H E T R E A T M E N T O F A L C O H O L DE P E N D E N C EA. Anti-Dipsotropic Activity of Daidzin and Crude Extract of RPFor more than a millennium, extracts containing RP or FP have been used apparently safely and effectively for the treatment of ‘‘alcohol addiction’’ in China.
Intake of Kudzu may help reduce alcohol consumption in those with abusive consumption of alcohol.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=100) Red Wine and Resveratrol
Date:
May 23, 2005 09:20 AM
The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: Implications for protection against coronary heart disease Authors: Pace-Asciak, Cecil R.a; Hahn, Susanb; Diamandis, Eleftherios P.b; Soleas, Georgec; Goldberg, David M. Affiliations: a. Department of Pharmacology, University of Toronto and Research Institute, Hospital for Sick Children, Toronto, Canada b. Department of Clinical Biochemistry, University of Toronto, 100 College Street, Banting Institute, Toronto, Ontario, M5G 1L5, Canada c. Andres Wines Ltd., Grimsby, Ontario, Canada Keywords: Atherosclerosis; Thromboxane B2; Hepoxilins; Anti-oxidants; Resveratrol; Quercetin Abstract: A number of lines of evidence suggest that red wine may be more effective than other alcoholic beverages in decreasing the risk of coronary heart disease (CHD) mortality. This protection over and above that due to ethanol itself may be explained by phenolic components with which red wines are richly endowed. We have studied the effects of the trihydroxy stilbenetrans -resveratrol on human platelet aggregation and on the synthesis of three eicosanoids from arachidonate by platelets, i.e. thromboxane B2 (TxB2), hydroxyheptadecatrienoate (HHT) and 12-hydroxyeicosatetraenoate (12-HETE). These effects were compared with the actions of other wine phenolics (quercetin, catechin and epicatechin) and antioxidants (a-tocopherol, hydroquinone and butylated hydroxytoluene). trans-Resveratrol and quercetin demonstrated a dose-dependent inhibition of both thrombin-induced and ADP-induced platelet aggregation, whereas ethanol inhibited only thrombin-induced aggregation. The other compounds tested were inactive. trans-Resveratrol also inhibited the synthesis of TxB2, HHT, and to a lesser extent 12-HETE, from arachidonate in a dose-dependent manner. Quercetin inhibited only 12-HETE synthesis, and hydroquinone caused slight inhibition of TxB2 synthesis, the remaining compounds being ineffective. De-alcoholized red wines inhibited platelet aggregation; their ability to inhibit the synthesis of TxB2 but not that of 12-HETE from labelled arachidonate by washed human platelets was proportional to their trans-resveratrol concentration. These results are consistent with the notion that trans-resveratrol may contribute to the presumed protective role of red wine against atherosclerosis and CHD.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=95) KudZu, Treatment of alcohol dependence or alcohol abuse
Date:
May 19, 2005 09:29 AM
For millennia, folk medicines have been used to treat ‘‘alcohol addiction’’ in China. A thorough literature search of the ancient Chinese pharmacopoeias revealed a long list of traditional remedies, including the 16 ‘‘stop-drinking’’ formulae of Sun Simiao (ca. 600 AD) and the ‘‘anti-alcohol addiction’’ formula of Li Dongyuan (ca. 1200 AD), 2 of the most reputed ‘‘medical doctors’’ in the history of Traditional Chinese Medicine. However, like those discovered by the ancient Romans,11 most of the ancient Chinese remedies for ‘‘alcohol addiction’’ were based on psychological aversion: to deter patients from further drinking by associating alcohol drinking with an unpleasant experience. Interestingly, as time went by, treatments based solely on psychological aversion were gradually eliminated from the ancient Chinese pharmacopoeias, presumably because of their ineffectiveness and/or undesirable side effects. The only remedies that have survived this historical trial-anderror scrutiny are those consisting the root (Radix puerariae, RP) or flower (Flos puerariae, FP) of Pueraria lobata (a medicinal plant known to the West as kudzu). It was on the basis of this historical backdrop, we initiated the search of safe and efficacious anti-dipsotropic (alcohol intake suppressive) agents from RP. This approach has led to the discovery of daidzin,12 an isoflavone that has since been shown to reduce alcohol drinking in all alcohol preferring animal models tested to date.
Alcohol abuseAlcohol abuse and alcohol dependence (i.e., alcoholism) are serious public health problems of modern society. In the United States alone, an estimated 13 million adults exhibit symptoms of alcohol dependence due to excessive alcohol intake, and an additional 7 million abuse alcohol without showing symptoms of dependence according to U.S. Government projections from studies conducted in the mid-1980s. Alcohol dependence and abuse are very expensive: in economic and medical terms, it will cost the U.S. well over $200 billion in 1991 with no prospect of falling or leveling off. The social and psychological damages inflicted on individuals as a consequence of alcohol abuse, e.g., children born with fetal alcohol syndrome (FAS) and victims of alcohol-related accidental death, homicide, suicide, etc., are immense. While it is generally accepted that alcoholism and alcohol abuse are afflictions with staggering international economic, social, medical, and psychological repercussions, success in preventing or otherwise ameliorating the consequences of these problems has been an elusive goal. Only very recently the public view that alcoholism and alcohol abuse are remediable solely by moral imperatives has been changed to include an awareness of alcoholism and alcohol abuse as physiological aberrations whose etiology may be understood and for which therapy may be found through scientific pursuits. Both alcohol abuse and dependence arise as a result of different, complex, and as yet incompletely understood processes. At present, alcohol research is in the mainstream of scientific efforts. Our studies on alcohol (ethanol or ethyl alcohol) have been based on the hypothesis that its abuse can ultimately be understood and dealt with at the molecular level. Such a molecular understanding, if achieved, would provide a basis for the identification and development of appropriate therapeutic agents. Our view hypothesizes that the clinical manifestations of alcoholism and alcohol abuse are the consequence of aberrations or defects within one or more metabolic pathways, affected by the presence of ethyl alcohol. In order to test this hypothesis, our initial studies focused on physical, chemical, and enzymatic properties of human alcohol dehydrogenase (ADH), the enzyme that catalyzes alcohol oxidation according to the following reaction formula: CH.sub.3 CH.sub.2 OH+NAD.sup.+ .fwdarw.CH.sub.3 CHO+NADH In addition, our studies more recently have focused on the aldehyde dehydrogenases (ALDH) which catalyze the subsequent step in the major pathway of ethanol metabolism according to the following reaction formula: CH.sub.3 CHO+NAD.sup.+ .fwdarw.CH.sub.3 COOH+NADH Prior to our research (for example, see Blair and Vallee, 1966, Biochemistry 5:2026-2034), ADH in man was thought to exist in but one or two forms, primarily in the liver, where it was considered the exclusive enzyme for the metabolism of ethanol. Currently, four different classes of ADH encompassing over twenty ADH isozymes have been identified and isolated from human tissues. There is no reason to believe that all of these ADH isozymes are necessary to catalyze the metabolism of a single molecule, ethanol, even though all of them can interact with it. We have proposed that the normal function of these isozymes is to metabolize other types of alcohols that participate in critical, physiologically important processes, and that ethanol interferes with their function (Vallee, 1966, Therapeutic Notes 14:71-74). Further, we predicted that individual differences in alcohol tolerance might well be based on both qualitative and quantitative differences in isozyme endowment (Vallee, 1966, supra).
Our research has established the structures, properties, tissue distribution, and developmental changes for most of the ADH isozymes, which while structurally quite similar, and presumed to have evolved from a common precursor, are functionally remarkably varied. Of the more than 120 publications from our laboratory that relate to the above subjects, the following, arranged in six categories, are especially useful for instruction in the prior art.
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(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=79) Composition and Method of increasing Testonsterone...
Date:
May 17, 2005 04:01 PM
Composition and method for increasing testosterone levels Abstract This invention provides compositions and methods related to the administration of deer antler, one or more nor-testosterone precursors, and one or more testosterone precursors, to increase testosterone levels, treat sexual dysfunction, improve sexual function, improve energy, enhance feelings of well-being and increase muscle mass in males. This invention also provides for inhibitors of the enzymes aromatase and/or 5-alpha reductase, to support testosterone levels and avoid undesirable metabolites. May reduce DHT: By using velvet deer antler along with the testosterone and nor-testosterone precursors, the antler promotes youth film testosterone levels while balancing and ameliorating dangerous spikes in these levels. Another embodiment of the invention includes herbs that inhibits 5-alpha-reductase reducing undesirable levels of dihyrotestosterone. Another embodiment includes chrysin, which inhibits aromatase and the production of estrogenic steroids. Deer antler (called Rokujo in Ancient Chinese Medicine) is used for its sexual-reinforcing and anti-aging actions. Wang et al., 36(7) CHEM. PHARM. BULL. 2587-92 (1988). Velvet antler is living tissue that grows at a rate of up to 2 cm/day in some species. Cartilage, bone and support tissues such as nerves, blood vessels and hair follicles of the antler also evidence accelerated growth. Antler is the only mammalian organ that regenerates. These features, responsible for the accelerate growth of velvet antler are likely to be caused by either unique regulatory substances or substances found in other tissues but at lower levels. It is believed that factors actually responsible for the rapid regeneration of the velvet antler can explain the powerful health benefits of the product. Specifically, velvet deer antler regulates the adrenal cortex and energy metabolism, promotes sexual function and growth, and strengthens resistance. Its functions fall into the major categories of general body strengthening, healing, promoting blood cell growth and improving immune and cardiovascular function.
Some of velvet deer antler's key ingredients include lysophosphatidyl choline, with hypotensive activity, phosphatidyl ethanolamines, sphingomyelin, phosphatidyl choline hypothanthene and uridene, with monoamine oxidase (MAO)-inhibiting and anti-aging effects; polyamines spermine, spermidine and putrescine, with RNA polymerase stimulating effects; gangliosides that may promote memory and learning; and anti-inflammatory amino acids. A wide variety of growth factors are also found in velvet, and may be associated with its growth-promoting activity. Tsujibo et al., 35(2) CHEM. PHARM. BULL. 654-59 (1987). As taught by ancient Chinese medicine, deer antler tonifies the yang, primarily deficient yang of the kidneys, spleen and heart. Because kidneys are the seat of the basal yang, the most important use of this class of herbs is to tonify the kidney yang, whose principal manifestation of deficiency is systemic exhaustion. Yang deficiency causes impotence, spermatorrhea, watery vaginal discharge, infertility, enuresis, polyuria, wheezing and daybreak diarrhea. Patients with deficient kidney yang very often have decreased plasma thyroid hormone binding proteins, 24-hour urinary 17-ketosteroids, and decreased rate of glycolysis. When treated with tonifiers such as deer antler, these measurements return to normal ranges. BENSKY ET AL., CHINESE HERBAL MEDICINE, MATERIA MEDICA, REVISED EDITION Eastland Press, Seattle, Wash. (1993).
Deer Antler Velvet Full Spectrum Planetary Formulas 30CtDeer Antler Velvet Full Spectrum 60ct
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=62) Bee Propolis
Date:
May 12, 2005 05:14 PM
-- VitaNEt® VitaNet ® Staff
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=45) Nattokinase: Food For Cardiovascular Health 
Date:
May 10, 2005 10:13 AM
Say it Ain't Soy! Yes, but this soybean is different! What makes it different is simple. after hours of fermentation, the boiled soybean metamorphose to an ancient medicinal food called "Natto" pronounced "Nah'-Toe." Natto may just be the "perfect food," producing 18 valuable amino acids and an enxyme natokinase that may challenge the pharmaceutical industry's best "blood-clot busters." Natto, which has recently attracted attention throughout the world, is the third most popular type of fermented soybean in the japanese diet. Japan has the highest average longevity in the world, which may partly be attributed to a high consumption of natto. When compared with ordinary soybeans, the natto produces more calories, protein, fiber, calium, potassium and vitamin B2. Its high protein and economical price in terms of protein per gram has earned it the sobriquet. "Hata-ke no niko," a meat of the field. This nickname appears well deserved, as in comparison with an equivalent amount of beef, natto has slighly less protein (16.5 grams to 21.2 grams),but contains more carbohydrates and fiber, and is also higher in calcium, phosphorous, iron and vitamin B2. Plus, it has nearly double the calcium and far more vitamin E to boot. According to legend, the first person to originate traditional Japanese natto was the famous warrior Yoshiie Minamoto during the Heian era of Japanese history (794 - 1192 A.D.). The horse was extremely important to the Japanese samurai warrior of the period, and great care was given to provide suitable provisions for the horses when armies were on the move. Typically, boiled soybeans were cooled down, dried in teh sun and packed immediately in rice straw bags for transport with the army. If the army was on a rapid deployment, the boiled soybeans were packed hastely into the rice straw bags with out cooling or drying. The rice straw just happened to contain a harmless and naturally occuring microorganism, Bacillus Subtilis that fermented the soybeans and producted natto with its characteristic sticky texture. Initially, the soybeans were presumed to have spoiled until yashiie minamoto observed that his horses were "picky eaters" and demonstrated a preference for the "spoiled" Soybeans or natto. One day, Minamoto demonstrated tremendous courage and dipped his fingers into the seemingly rotten goo. To his astonishment, the fermented soybeans were not only edible but had a distinct umami flavor. Minamoto was responsible for introducing natto to northwestern Japan, where he ruled. To this day natto is especially popular in that region of Japan as a folk remedy for fatigue, beriberi, dysentery, heart and vascular deseases. The most distinctive features of natto are the adheasive surrounding the soybeans and the strong flavor. The sticky material has been shown to consist of poly-g-glutamic Acid (D and L) and polysaccharides (Levan-form fructan), and the strong "cheese like" flavor is due to the presence of pyrazine. These features sometimes make it hard for some people, especially people from other countries, to accept natto; however, these are the main factors which give natto the outstanding properties. Natto, which has recently attracted attention throughout the world, is a familiar part of the Japanese diet. Technical Aspects of Nattokinase: Nattokinase produces a prolonged action in two ways: it prevents the formation of thrombi and it dissolves existing thrombus. Nattokinase orally administrated to twelve healthy adults indicated elevations in the breakdown products of the fibrin and the ability of the blood to break down fibrin called eugobulin fibrionlytic activity (EFA). These results suggest the ability of nattokinase to accelerate fibrinolysis in the blood for a prolonged period of time. FDP levels in the adults drastically increased 4 hours after the administration of the nattokinase, indicating that fibrin within the blood vessels is gradually being disolved with repeated intake of nattokinase. By measuring the EFA & FDP levels, the activity of nattokinase has been determined to last for 8 to 12 hours. An additional parameter for confirming the action of NATTOKINASE following oral administration is a rise in blood levels of tissue plasminogen activator (TPA) antigen, which indicates a release of TPA from the endothelial cells and/or the liver and the endogenous production of plasmin (The body's blood clotting buster).6,7 In 1995, researchers from Miyazki Medical College and Kurashiki Unerversity of science and arts in Japan studied the effects of nattokinase on the blood preasure in both animals and human subjects. In addition, the researchers confirmed the presence of inhibitors of angiotensin converting enzyme (ACE) within the test extract, which consisted of 80% ethanol extract of lyophilized viscous materials of natto. ACE causes blood vessels to narrow and blood pressure to rise - by inhibiting ACE; nattokinase has a lowering effect on blood pressure.1,2 The same natto extract was then tested on human volunteers with high blood pressure. Blood pressure levels were measured after 30 grams of lyophilized extract (Equivalent to 200 grams of natto food) was administered orally for 4 consecutive days. In 4 out of 5 volunteers, the systolic blood pressure (SBP) decreased on average from 173.8+- 20.5 mmHg to 154.8+-12.6 mmHg. Diastolic blood pressure (DBP) decreased on average from 101.0+- 11.3 mmHg to 91.2+- 6.6 mmHg. On average, this data representes a 10.9 percent drop in SBP and a 9.7 precent drop in DBP. 1,2,6 Disclaimer: The above artical is for informational purposes only and is not intended to diagnose or treat a particular illness. The reader is encouraged to seek the advice of a holistically competen t licensed professional health care provider. The information in this artical has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any desease.
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About focus
DMAE
Saw palmetto is a tree type of plant which is scientifically known as Serenoa repens. It is abundantly found along the coast of southeastern part of USA. This plant bears flowers which comes in yellow and produces fruits which are berry - like and reddish black in color. Saw palmetto supplements are extracted from the plant’s berries. The berries are rich in fatty acids and phytosterols. Saw Palmetto berry extracts are made by drying the berry and mixing it with a solvent like hexane and ethanol. 
