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Probiotic, Red Yeast Rice Extract Combo May Cut Cholesterol
May 16, 2017 10:44 AM
New research out of Prague has suggested those suffering from high cholesterol issues may find relief when a certain probiotic is added to red yeast extract. Results were seen as early as six weeks with significant results noted at 12 weeks. B.Longum, reduces cholesterol absorption in the large intestine, inhibiting it from getting into the bloodstream while red yeast extract inhibits the liver from forming cholesterol cells. Due to the lowering cost of statins, the supplement may face some competition when launched into the large global market.
Read more: Probiotic, Red Yeast Rice Extract Combo May Cut Cholesterol
'Red Yeast Rice' Statin Alternative Not Harmless Either, Study Says
February 02, 2017 07:59 AM
If you suffer from high cholesterol, you are probably being prescribed a statin. Along with the effectiveness of statins to treat cholesterol issues, there is also the risk of side effects such as muscle and liver damage. For a while, red yeast rice has been recommended as a natural alternativeto prescribed statins. However, it has recently been found that this alternative choice can also increase muscle and liver injury. This is believed to be due to the fact that the active ingredient in each is monacolin K.
"red yeast rice could increase risk of muscle injury or liver damage."
What Are Some Natural Cholesterol Lowering Supplements?
December 10, 2013 02:30 AM
What Are Some Natural Cholesterol Lowering Supplements?Cholesterol is a lipid, or a fat, which is produced by the liver. Though many know it not, cholesterol is essential for the normal function of the body. Amazingly, each and every cell of the body contains cholesterol in its outer layer. This lipid serves several critical functions. Most importantly, cholesterol aids in building and maintaining cell membranes. The compound also determines which elements can pass through a cell membrane and which cannot; put differently, it determines cell permeability. The compound is also essential in the production of sex hormones, including androgens and estrogens.
LDL and HDL
Like most other chemical elements found in the body, cholesterol is only helpful if it is available in the right proportions. Low or high levels of cholesterol are harmful. However, high cholesterol levels can cause the most devastating effects on health. It is of great importance, to control cholesterol levels in the body. Failure to do this, you are at risk of developing several health complications. Some of these include atherosclerosis, a condition where arteries become extremely narrow to allow proper circulation; heart attack, caused by clogged arteries; stroke, caused by blood clots that prevent arteries or veins from transporting blood to the brain; and angina, a condition that develops when the heart muscles do not get enough blood.
About Cholesterol Levels
Cholesterol levels can always be brought to optimal levels by behavior and lifestyle change. This may include avoiding foods saturated in fats, quitting smoking and drinking, and exercising. There are also supplements that are quite effective in restoring cholesterol levels to the optimal levels. Some of the popular and effective supplements include red yeast rice, niacin, and guggul. Others are fish oil and green tea extracts. Though different from the outlook, all cholesterol supplements achieve their objective in a similar or closely related ways. Most importantly, the supplements are useful in raising HDL (high density lipo-protein also called good cholesterol) levels while at the same time lowering triglycerides (another class of fats found in the blood stream).
Diet To Lower Cholesterol
December 26, 2012 12:07 PM
Cholesterol is found naturally within the human body, particularly, in skin, internal organs, nerves, brain, cell membranes and bloodstream. This wax like compound is very important for the body's normal functioning. However, when there is excessive cholesterol buildup within the body, your health is at risk, because it gets deposited within the blood vessels. This article will talk about how to lower cholesterol levels through diet.
Consequences of Excessive Cholesterol Levels
Excessive cholesterol levels can cause dangerous ailments. Food habits as well as lifestyle changes are a few of the main reasons behind its rising level. Presented below are a few of the medical problems associated with high cholesterol levels within the body. When excess cholesterol is deposited on the inside of the arteries, flow of blood is interrupted which leads to inadequate supply of blood to the body. One of the organs that are mostly affected by high cholesterol levels is the heart. Extreme cases might lead to cardiovascular diseases such as heart attacks. Blocked arteries and reduced blood flow may lead to blood coagulation. Also, if blood supply to the brain is impaired, it can lead to confusion and stroke.
Research And Foods
Research has indicated that a diet which includes a daily consumption of oats, sterol based foods, nuts, soya based products and fish is extremely effective in decreasing the amount of cholesterol within the body. In fact, it is as effectual as taking cholesterol medication, and definitely a preferable as well as less costly option, with very little or no side effects. However, if you suffer from any special health condition, make sure you first speak with your healthcare professional before you go on a diet that is low in cholesterol. If you are currently taking some medication, you should check with your doctor to make sure the drugs are okay with the low cholesterol food.
Different Foods that Can Lower Cholesterol
Oats provides your body with soluble fiber that is beneficial in decreasing bad low density lipoprotein (LDL) cholesterol. Foods that contain oat bran, whole oat flour and oatmeal are extremely healthy as well as filling. Oat bran cold cereal and hot oatmeal porridge have been traditionally been eaten for breakfast, however you can include ground oatmeal to casseroles, baked foods and soups as well.
Nuts contain lots of fiber, protein, vitamins, polyunsaturated and monounsaturated fats, phytonutrients, antioxidants and plant sterols. They are not difficult to eat. All you need to do is remove the shell and put a handful in your mouth, lengthy preparations are not necessary.
Foods Rich in Soluble Fiber
You can keep your cholesterol levels low by regularly consuming foods that contain high amounts of soluble fiber. Soluble fiber adheres to cholesterol within the blood to flush it out. It also promotes healthy digestion.
Aside from oats, other examples of foods rich in soluble fiber:
Other foods that can lower cholesterol levels in the blood
However, you must bear in mind that even though eating foods that contain low cholesterol is definitely beneficial, these foods will not cure existing problems. Eating the foods mentioned above regularly in moderation and doing sufficient exercise is the secret to enjoying good health.
There are some supplements known to help lower cholesterol as well:
These are safe and effective ways to help reduce unwanted cholesterol.
The Benefits of the Amazing Duo of CoQ10 and Red Yeast Rice
March 11, 2012 03:08 PM
What Is Cholesterol?
Cholesterol is a substance produced by the liver that provides a number of benefits to the body. A problem occurs when the level of blood LDL or bad cholesterol goes beyond a normal level. High level of bad cholesterol in the body can inflict damage to the arteries during the process of oxidation which can lead to the heavy accumulation of stiffened fats and deposits in the walls of the arteries. This can constrict the arteries that eventually lead to a minimal flow of oxygen-rich blood to the heart and brain. Inadequate supply of blood to the heart and brain can trigger heart attack and stroke. When the kidney perceives an inadequacy in the supply of blood to the brain and heart, it produces substances that help in increasing the supply of blood to these organs. However, in effect, it also increases blood pressure.
Many serious health complications emanate from abnormally high levels of bad cholesterol or low density lipoprotein (LDL) in the body. As people get older, their awareness about maintaining an optimum level of cholesterol should increase significantly. Undeniably, cardiovascular diseases that are triggered by high levels of cholesterol in the body have been one of the major causes of death worldwide.
red yeast rice
Intake of red yeast rice is considered to be one of the most effective alternative ways to lower the level of cholesterol in the body. It is produced by fermenting a certain type of red yeast that is poured over the rice. Researchers believed that red yeast rice contains high levels of substance lovastatin that inhibits the production of enzyme HMG-CoA reductase which is responsible in regulating the production of cholesterol in the body. red yeast rice actually contains sufficient amount of monacolin K and 8 more monacolin substances that are work like statin drugs in reducing the level of cholesterol. Basically, the substances prevent the liver from producing alarming level of bad cholesterol.
Lowering Effects of LDL
red yeast rice is a great alternative choice for patients who are searching for non-prescription ways of lowering their cholesterol. A clinical study shows that red yeast rice can significantly lower the level of cholesterol in the body by as much as 20% without exposing the victim to the risk of suffering from muscle pain. Another study reveals that after taking 1800mg of RYR daily for 12 weeks, the users' bad cholesterol level have significantly drop by 27%.
red yeast rice is actually an FDA-recognized dietary supplement. It is renowned for its capacity to work similar to a statin drug that effectively drives the body to achieve an optimum level of cholesterol. A number of scientific studies revealed that intake of red yeast rice can significantly lower the levels of bad cholesterol and triglycerides in the body. Furthermore, studies show that continuous intake of red yeast rice can contribute a lot in improving the amount of total cholesterol.
Together with red yeast rice, CoQ10 make an amazing duo in lowering the level of bad cholesterol in the body and promote overall cardiovascular health. Intake of CoQ10 is highly recommended to people who take red yeast rice because CoQ10 provides energy and strength to the heart when pumping blood to other organs. When used together, CoQ10 and red yeast rice can increase the transfer of oxygen and energy between the cells and the blood which leads to a significant reduction in the level of cholesterol produced.
Red Yeast Rice for Reducing Cholesterol
February 16, 2012 08:06 AM
How does red yeast rice Reduce Cholesterol?
Maybe you have heard about it that some people said that red yeast rice is very effective for decreasing the cholesterol level on our body. Some people have tried putting it on their diet program to see how it works, while some others just stick to the medicines. But mostly, people does not even know what cholesterol is and why should they control the amount of it on their body.
Cholesterol is a fat substance produced by the liver and is important to allow your body to work properly. It helps the conversion process of vitamin D. It creates and controls cell membranes. It is also essential for many productions of hormones. And there are still much more benefits your body can get from cholesterol.
As long as the amount is perfect, cholesterol is a beneficial substance for your body. But having too much of it on your body is really not healthy. It can stick to your arteries and narrow it down. Therefore, your blood could not flow smoothly. It can lead you to a heart attack, coronary heart, stroke and other life-endangering diseases. That is why it is important to control the amount of cholesterol inside your body.
red yeast rice is a kind of rice that was fermented by red yeast. Since about a thousand years ago, red yeast has been commonly used in Chine as a natural food colorant and the main ingredients of rice wines. They also used it as a traditional medication for improving blood circulation and helping many kinds of digestion problems.
red yeast rice
Even so, there are still many scientist and doctors who does not believe if red yeast rice is safe enough for human to consume. Therefore, they did some trials. Firstly, they tried it to animal. They fed it the several kinds of animal continuously. The result shows that no damage is shown on the lungs, livers, kidneys, or any other organs. After that, they tried it to human where some people are volunteering. He result shows almost the same. There were some side effect such as heartburn and indigestions, but the number is very negligible and level is low.
Some other researches had been done to measure how effective is it in reducing cholesterol level. The results show that red yeast rice contains Cholestin that is effective to remove bad cholesterol (LDL) but not affecting good cholesterol (HDL) at all. The results also show that people who consume 1.8 grams of it per day can lower their cholesterol for about 27% in twelve weeks only.
Although it is effective in lowering the cholesterol, pregnant or breastfeeding women are not recommended to consume it. It is also not recommended for people who have a severe heart disease or high cholesterol. Those people are usually consuming statin given by their doctor. Statin is a lot better in reducing cholesterol and it is not wise to replace it with any other supplement.
Controlling your cholesterol level is very important in order to live a healthy life for as long as possible. Besides putting red yeast rice on your diet program, you also need to have a healthy lifestyle by consuming nutritional foods, avoiding alcohols, and doing exercise regularly.
Red Yeast Rice New Larger 240 Veg-Capsule Size
September 28, 2009 02:40 PM
red yeast rice 600 mg - 240 Vcaps
When it comes to red yeast rice, purity and potency are NOW’s top priorities. As part of our Genuine Whole Foods line, NOW® red yeast rice is welltested and free of potentially harmful contaminants, such as citrinin, a fermentation byproduct. Our QA/QC experts are involved throughout all stages of manufacturing, from inspection and delivery of raw materials, to the final packaging process. Best of all, NOW continues to offer red yeast rice at prices that are well below our competitors.
Looking for a good way to break the ice with new or uncertain customers? Just ask them how their digestion is. It will tell you volumes about their overall health status, allowing you to more effectively assist them in choosing the products that are best for their unique needs. For those who are in need of digestive support, NOW® Psyllium Powder is a great place to start. It offers all the benefits that has made psyllium the digestive staple it is today, in a form that allows for easy mixing or encapsulation.
Omega Red And Cholesterol
August 28, 2009 05:50 PM
Red Omega™ With red yeast rice, CoQ10 & Omega-3 Fish Oils in Softgels
Individually, Omega-3 fatty acids, CoQ10, and red yeast rice extracts have each been shown in numerous studies to exhibit a wide range of cardio-beneficial properties. Until now, anyone interested in reaping the benefits of these three products had limited options, with the exception of purchasing multiple products. Red Omega™ has made it possible for today’s cardiovascularconscious health enthusiast to reap the benefits of all three compounds in one convenient dietary supplement.*
NOW® Red Omega™ is an innovative complex formula that was developed to help support healthy cardiovascular function. Omega-3 Fish Oil and CoQ10 have each been the focus of extensive research, and are now used by millions on a worldwide scope. Combined, however, they exert a powerful synergism that may potentially provide even greater health benefits. The organic red yeast rice in this supplement is carefully produced to avoid the presence of citrinin, a sometimes toxic by-product of the fermentation process.*
NOW® Introduces Genuine Whole Food™ Labeling
September 27, 2008 01:23 PM
NOW is excited to highlight our line of Genuine Whole Food products with a new icon. These existing products include a wide range of items, including NOW® Flax, Alfalfa Juice, Blue Green Algae, Kelp, Spirulina, Aloe, Hoodia, Colostrum, and Chlorella. One of the most exciting to join this new product category is an Organic red yeast rice that is sourced right here in the United States.
In order to provide you and your customers with the finest possible product, these items undergo a delicate process that helps retain the highest concentrations of nutrients and other beneficial extracts. They are minimally processed without adding or creating new isolates, and we do not spike our active ingredients. This results in safe ingredients that provide nutrients in their original form. NOW® Genuine Whole Foods are concentrated using only deionized water; no harsh chemical solvents are used at any stage during the process.
When it comes to the products that enter your body, natural is always better. Not only are natural products free of potentially dangerous chemicals, they also contain a wide range of nutrient compounds that cannot be recreated in a laboratory. All NOW Genuine Whole Food supplements are 100% natural and free of artificial colors, flavors, sweeteners, and preservatives. Our new Genuine Whole Foods icon identifies this commitment made to product quality. Each product delivers a ratio of nutrients similar to that found in natural food sources. This results in greater nutrition that your body can use in the most effective manner possible.
Unlike other companies that offer only a small selection of Whole Food-based products and ingredients, or none at all, NOW has a diverse selection of 68 SKUs that encompasses a wide range of health and wellness needs.
Red Yeast Rice
August 04, 2008 04:07 PM
Many natural substances that are capable of lowering blood fats and cholesterol levels that are potentially harmful have emerged. No one is suggesting that there is a magic pill that will promote healthy cholesterol levels, but nature has provided us with some specific compounds that are capable of enhancing both dietary and lifestyle changes in order to improve cardiovascular health. One of the most impressive of these compounds is that of red yeast rice, which is a fermented food substance that has been traditionally used for its red-coloring abilities in meats and other foods. Additionally, red yeast rice offers some extremely beneficial therapeutic effects, as it is the source of certain compounds that can successfully reduce cholesterol.
Pharmaceutical companies have been making cholesterol lowering drugs for many years, but natural supplements are now available which offer the consumer a way to lower cholesterol in natural way. This is extremely good news for those people who are suffering from moderately elevated cholesterol levels and is looking to avoid synthetic drug preparations and the side effects that follow.
Most of us are now aware that high serum cholesterol level is what predisposes us to cardiovascular disease along with other degenerative conditions. Learning how to control our cholesterol levels, especially the LDL and blood triglyceride levels, while keeping HDL cholesterol at desirable levels can be an extremely frustrating task. By decreasing our consumption of animal fats and certain types of oils, eating more fiber and taking prescription drugs or natural alternatives, we can easily accomplish our goal.
Dietary changes should be targeted first, but turning to cholesterol-lowering prescription drugs has both its pros and cons. Pharmaceutical preparations come with considerable side effects. Some of the drugs that are most effective contain enzymatic inhibitors that prevent the synthesis of cholesterol. red yeast rice accomplishes the same enzyme inhibition but is considered a natural alternative that safely promotes healthy serum cholesterol levels.
Coronary heart disease refers to the damage that is done to the heart when the coronary arteries become blocked or narrowed because of a buildup of plaque or oxidized cholesterol. When cholesterol buildup breaks off and lodges in the heart or brain, this causes a heart attack or stroke. An extremely common disorder of developed nations, coronary heart disease causes more deaths in the US than any other disease. Many people who die from heart disease are ironically in otherwise good health.
High blood pressure, which is a related disorder, is similar in the fact that both can be a silent killer. The symptoms of coronary heart disease include impotence, heart attack, or stroke. Although the mortality rates from coronary heart disease have declined over the last twenty years, the reason for this decline is shown to be the better medical technology that is available. Claiming more than one million deaths every year, coronary heart disease is still a major issue facing the American society.
In order to help us prevent heart disease, we have been given many dietary guidelines. However, many of us are not motivated enough to make the dietary changes that could literally save our lives. The major causes of coronary heart disease include obesity, smoking, alcohol, high protein and high saturated fat diet, lack of exercise, high blood pressure, high cholesterol levels, and a genetic predisposition.
Psyllium Husk Fiber Fact Sheet
December 08, 2005 04:28 PM
Psyllium Husk Fiber Fact SheetNeil E. Levin, CCN, DANLA 8/1/05
LIKELY USERS: People with cholesterol or cardiovascular concerns.1-2 People wanting to increase fiber in their diet3-9
KEY INGREDIENTS: Psyllium Husk Powder, natural flavor
MAIN PRODUCT FEATURES: Psyllium is a true dietary fiber, even though it is classified by some as a laxative or mucilaginous fiber, and is a convenient way to increase intake of dietary fiber because of its high mucilage content. This bulking agent swells considerably when added to liquid, which can help to increase gastrointestinal transit time. This bulking action and increased transit time can play an important role in maintaining healthy gastrointestinal function.3-9 The FDA allows a health claim for products like psyllium husk that provide significant amounts of soluble fiber: Diets low in saturated fat and cholesterol that include 1.7 grams of soluble fiber per day from psyllium husk may reduce the risk of heart disease. One serving of NOW Psyllium Husk Fiber - Orange Flavored provides 2 grams of this soluble fiber.1-2
ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: This product has been tested by an independent laboratory to assay the fiber content. This is a vegetarian/vegan product.
SERVING SIZE & HOW TO TAKE IT: As a dietary supplement, mix 1 heaping teaspoon into at least 12 oz. of water or juice and consume immediately. Be sure to drink plenty of additional fluids throughout the day. Start with smaller amounts and gradually increase over several weeks.
For GI tract: Triphala, Detox Support, Probiotics, FOS, and healthy oils (fish, flax, olive, virgin coconut, virgin macadamia)
For cardiovascular health: Hawthorn extract, Tru-E Bio Complex (new September 2005), Heart Support, Heart Renew, Cholesterol Support, Cholestatin, Policosanol. red yeast rice CAUTIONS: None.
SPECIFIC: Do not use if you have a bowel obstruction or an ulcer. If you have chronic constipation, diabetes or are obese a physician should monitor the use of this dietary supplement. Side effects are possible with any dietary supplement. This dietary supplement may cause gastrointestinal pain, flatulence and abdominal pain. Tell your doctor if these side effects become severe or do not go away.
NOTICE: This food should be eaten with at least a full glass of liquid. Eating this product without enough liquid may cause choking. Do not eat this product if your have difficulty in swallowing.
GENERAL: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. Information given here may vary from what is shown on the product label because this represents my own professional experience and understanding of the science underlying the formula and ingredients. When taking any new formula, use common sense and cautiously increase to the full dose over time.
Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
1. [Code of Federal Regulations] [Title 21, Volume 2] [Revised as of April 1, 2002]
Sytrinol can lower Cholesterol by 27% - 34%
September 20, 2005 09:56 AM
Sytrinol – MultiPronged Heart Health
According to the American Heart Association, more than 60 million Americans suffer from on of more forms of cardiovascular imbalances. When we add in those individuals with blood cholesterol concerns, we see over 100 million Americans who may be in need of specific diet and lifestyle recommendations for achieving and maintaining heart health.
Aside from the generalized recommendations that we typically hear for heart health (lose weight, exercise more, and eat less fat and more fruits and vegetables) There are a number of potentially beneficial dietary supplements that may help to maintain cholesterol levels in the normal range. Among supplements there is a wide range of safety and efficacy between products—but a newer product called Sytrinol stands out for its clinical effectiveness.
Sytrinol is a patented blend of polymethoxylated flavones (from citrus) and tocotrienols (from palm fruit). One of the factors that sets Sytrinol apart from existing natural products for heart health is its multipronged approach to controlling multiple factors related to overall heart health—including control of cholesterol, cellular irritation, oxidation, triglycerides, and others.
While it is unarguable that cholesterol is an important contributor to overall heart health, it couldn’t be further from the truth that cholesterol is the “only” or even the most important factor when it comes to protecting your heart. Did you know that approximately HALF of all serious heart challenges each year are experienced by people with NORMAL cholesterol levels? If Cholesterol is not to blame, then what is?
In addition to total cholesterol levels (the “number” that you may know as 200 to 240 of other values in “mg/dl” units), we know how that LDL and HDL matter a lot (Low-density lipoprotein—the “bad” cholesterol, and High-density lipoprotein—the “good” cholesterol). We also know that some forms of the bad and LDL can be “Badder” than others—specifically those with lots of structural protein called “apolipoprotein B” (which tends to encourage LDL cholesterol to become embedded in your blood vessel linings—bad!). In addition to our total cholesterol, LDL, HDL, and the various apoproteins, we also need to know our triglyceride levels, our levels of cellular irritation, what our free radical load looks like, and what our antioxidant defenses are. Sytrinol addresses each of these important aspects of heart and health simultaneously.
The Sytrinol Solution
Polymethoxylated Flavones (PMFs) in Sytrinol are just what they sound like – flavonoid compounds with extra methoxy groups compared to “regular flavones. Like all flavonoids, the PMFs deliver potent antioxidant activity, but the PMF version is about three times more potent in its ability to address cholesterol levels (20% - 30% reduction in clinical Studies). The two primary PMFs are nobiletin and tangeretin.
In addition to the PMFs, Sytrinol contains palm tocotrienols—one of the most potent antioxidant nutrients known. An interesting effect of tocotrienols is a reduction in cholesterol synthesis in the liver—by a mechanism similar to (but safer than) the commonly utilized mechanism of inhibition of the HMG-CoA Reductase Enzyme.
Sytrinol is known to work via several unique mechanisms to reduce triglycerides (TG), total cholesterol (TC) and low-density lipoprotein cholesterol (LDL). First, by reducing DGAT activity (Diacylglycerol acetyl transferase) and increasing liver PPAR (Peroxisome porliferator-activated receptor)—Sytrinol can reduce overall synthesis of TG (DGAT inhibition). The overall effect is to reduce TG levels in the blood by two complementary mechanisms.
In terms of LDL effects, Sytrinol also reduces both Apolipoprotein B levels (ApoB—needed for the synthesis of LDL particles) and MTTP levels (microsomal triglyceride transfer protein-needed to transfer fat into the new LDL particles). By reducing levels of both these tructural LDL components, Sytrinol reduces overall LDL levels, and thus total cholesterol levels, in the blood.
The clinical results behind Sytrinol are impressive—showing a reduction in levels of total, LDL, and triglycerides by 27% - 34% within 4 weeks. In one of these studies, ApoB levels were reduced (suggesting reduced LDL) and ApoA1 levels were increased (suggesting increased HDL)—as would be expected based on the biochemistry of PMFs and tocotrienols.
Sytrinol is also wonderfully safe—and at the effective dose of 300mg daily, users will benefit from its multipronged effects. One aspect of Sytrinol safety that I especially like is the finding that, unlike some flavonoids like naringin from grapefruit, there are no known risks of drug interactions with the form of citrus derived PMFs found in Sytrinol (certain grapefruit flavonoids can interfere with liver enzymes needed to metabolize many prescription drugs).
Not since red yeast rice was removed from the market by the FDA, have we had a truly effective, multimechanism solution for cholesterol control (and nearly total heart health). There are certainly other options for addressing heart health and cholesterol levels, but among the available choices, such as policosanol, guggulipid, niacin, and plant sterols, we’re looking at about half the cholesterol-lowering ability (10% - 15% in most cases) compared to Sytrinol. If youre in the “borderline” zone of cholesterol levels (about 240mg/dl and below), you should absolutely consider Sytrinol to keep your cholesterol levels under control.
Kurowska EM, manthey Ja. Hypolipidemic effects of absorption of citrus polymethoxylated flavones in hamsters with diet-included hypercholesterolemia. J Argic food chem.. 2004 may 19;52(10):2879-86.
Kurowska EM, manthey Ja, Casaschi A, Theriault AG. Modulation of HepG2 cell net apolipoprotein B secretion by the citrus polymethoxyflavone, Tangeretin. Lipids 2004 feb;39(2):143-51.
Manthey JA, Grohmann K, Montanari A, Ash K, Manthey CL, Polymethoxylated flavones derived from citrus suppress tumor necrosis factor-alpha expression by human moncytes. J Nat Prod. 1999 mar;62(3)441-4.
Mora A, Paya M, rios JL, Alcaraz MJ. Structure-activity relationships of polymethoxyflavones and other flavonoids as inhibitors of non-enzymic lipid peroxidation. Biochem Parmacol. 1990 Aug 15;40(4):797-7.
Takanaga H, Ohnishi A, Yamada S, Matsuo H, Morimoto S, Shoyama Y, Ohtani H, Sawada Y. Polymethoxylated flavones in orange juice are inhibitors of P-glycoprotein but not cytochrome P450 3A4. J Pharmacol exp. Ther. 2000 Apr;293(1):230-6.
By: Shawn M. Talbott, PH.D.
Disclaimer: The above article is for informational purposes only and is not intended to diagnose or treat a particular illness. The reader is encouraged to seek the advice of a holistically competent licensed professional health care provider. The information in this article has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
New* Improved formula - Cholest-Response Lower Cholesterol
July 08, 2005 09:27 AM
New & Improved Formula!
4 tablets contain:
Suggested Use: Take 4 tablets each night or as recommended by your health care professional.
We offer Source Naturals at 46% OFF Man. Suggested Retail
Red Yeast Rice For Lipid Wellness
June 04, 2005 02:30 PM
Maintaining cardiovascular health is a fundamental strategy in the holistic healing system. It may be the most important thing you can do for your body. One of the factors for optimal cardiovascular health is keeping your lipid levels within the normal range. But with today’s fast-paced lifestyle, it’s hard to maintain a healthy diet and exercise program. red yeast rice is a natural product that supports maintenance of normal lipid levels. Source Naturals red yeast rice is standardized to 1.5% mixed mevinolinic acid monacolins. These monacolins block the synthesis of lipids in the liver by binding to the lipids production enzyme HMG-CoA reductase. Support your lipid wellness with the quality and science of Source Naturals red yeast rice.
The Liver and Lipid
The amount of lipid you consume in food is not the most important factor for regulating normal lipid levels. The liver manufactures approximately 80% of total body lipid while the other 20% comes from dietary sources. Our bodies require lipid but we can also get too much of it. Lipid is only harmful to us if it becomes oxidized. Oxidized lipid can cause damage to tissues and accumulate in blood vessels. Balancing the lipid produced by your liver is critical to your total lipid and your cardiovascular health.
red yeast rice has been used in China for centuries to make rice wine, to color and flavor foods such as Peking duck and as a health promoting food. It is prepared by fermenting a type of yeast (Monascus purpureus) over rice. red yeast rice is a complex product that contains several active ingredients including monacolins. Monacolins act as HMG-CoA inhibitors. HMG-CoA reductase is an enzyme that helps make lipid. By blocking its lipid producing action, the natural compounds in red yeast rice can help you maintain lipid levels that are within the normal range. A double blind clinical trial using red yeast rice and placebo with 80 human subjects was conducted at UCLA. After eight weeks with no changes in diet composition the group taking red yeast rice maintained healthy lipid levels.
Natural Support For Your Heart
Nature provides us with special compounds that allow us to explore safe alternatives to support our health. Taking personal responsibility for your health is at the heart of the wellness revolution. Changing your lifestyle is one of the most effective ways to take that responsibility and provide support and protection for your heart. A diet low in lipid, saturated fats and trans-fatty acids, and high in complex carbohydrates and fiber is important. Exercise regularly, quit smoking and supplement your diet with heart-healthy compounds such as red yeast rice, CoQ10, folic acid, garlic, omega-3 fatty acids, carnitine, hawthorn berry extract, arginine, vitamin E and tocotrienols. Source Naturals red yeast rice is standardized to 1.5% mixed mevinolinic acid monacolins. This standardization process provides you with the assurance that you are getting a consistent concentration of these compounds in each dose. red yeast rice is part of Source Natural’s extensive line of products scientifically formulated to provide support for your cardiovascular health.
Acute administration of red yeast rice depletes tissue CoQ10
May 13, 2005 03:00 PM
Basically, if you are taking a Cholesterol lowering product that works on the same order as prescription drugs, you need to supplement CoQ10 to replace what the body is removing.
British Journal of Nutrition (2005), 93, 131–135 DOI: 10.1079/BJN20041285 q The Authors 2004
Acute administration of red yeast rice (Monascus purpureus) depletes tissue coenzyme Q10 levels in ICR mice
VitaNet ® staff
Under-Reported (and Underappreciated) Cholesterol control.
May 12, 2005 10:00 AM
Under-Reported (and Underappreciated) Solutions for Cholesterol and Triglyceride Controlby Richard Conant, L.Ac., C.N.
Fat and human existence are inseparable. Setting aside the fear and loathing over fat in the body that pervades our culture, we understand that fat is our friend. We cannot live without fat.
The human body contains many different kinds of fats and fat-like molecules. Collectively known as "lipids" these fatty substances include fatty acids, lipoproteins, phospholipids, glycolipids, triglycerides, steroid hormones and the infamous, dreaded cholesterol.
Lipids (fats) are found everywhere in the body, performing a variety of vital functions. The brain is a fat-rich organ. Brain neurons and all other nerve cells are protected by a myelin sheath, made largely out of fatty material. Cell membranes consist almost entirely of phospholipids (lipids that contain phosphorus) arranged in a sandwich-like double layer embedded with proteins. Sex hormones are lipids, belonging to the group of complex lipid molecules known as "steroids." Vitamin D is a lipid.
The body stores and transports fatty acids in the form of triglycerides. A triglyceride contains three fatty acid molecules, which have a chain-like structure, linked to glycerol. (There are also mono- and di-glycerides, which have one and two fatty acid chains, respectively, attached to glycerol.)
Like many other things necessary to life, fat is a two-edged sword. Fat insulates us from the cold, cushions and protects our vital organs and serves as a storehouse for energy. Yet, when present in excess to the point of obesity, fat threatens health, happiness, self-esteem, social standing and longevity. The same is true of other lipids, most notably triglycerides and cholesterol. Transported throughout the body in the bloodstream, these essential lipids become a health liability when the blood contains too much of them.
Keeping fat in it its proper place, not eliminating or drastically reducing it, is the goal we should seek. In the blood, lipids must be maintained at healthy levels and ratios. When they are, an important foundation of good health is established.
How do we keep the blood lipids we need——triglycerides and the various forms of cholesterol——balanced at healthy levels? Diet and exercise are indispensable, these basics must come first. Along with the recommended dietary practices, a number of nutritional approaches offer help for maintaining healthy blood lipids. We will now give several of these a closer look.
In 1990, an herb used for centuries in the Far East was introduced to U.S. consumers. This herb, called "gum guggul," is proving to be one of the most effective natural cholesterol-lowering agents ever discovered. It also brings triglycerides down and raises HDL, the "good" cholesterol. The changes are substantial; gum guggul single-handedly normalizes the entire blood lipid profile, even in people with high starting levels of cholesterol and triglycerides.
Gum guggul, also called simply "guggul," is a gummy resin tapped from the Commiphora tree. A cousin of myrrh gum, guggul has been used by Ayurvedic herbalists of India for at least 3,000 years; texts dating from around 1,000 B.C. mention the herb. Guggul was traditionally given for rheumatism and poor health caused by excess consumption of fatty foods. One ancient Sanskrit text describes in detail what happens in the body when blood fats are out of balance, due to sedentary lifestyle and overeating. The name of this condition has been translated as "coating and obstruction of channels."
Intrigued by the obvious similarity between "coating and obstruction of channels" and arteries clogged by fatty plaque, Indian researchers initiated a series of experimental and clinical studies in the 1960's to see if gum guggul would lower excess blood lipids.1 Both human and animal studies consistently showed cholesterol and triglyceride reductions.
Detailed pharmacological studies showed that guggul's lipid-lowering effects are produced by compounds in the resin called "guggulsterones."2 An Indian pharmaceutical firm then patented a standardized extract of gum guggul under the trade name "Gugulipid." The product contains a uniform 2.5 percent guggulsterones, which is higher than guggul resin in its natural state.
Because Gugulipid guarantees the necessary intake of guggulsterones needed for blood fat reduction, it has become the product used in clinical research. Phase I efficacy safety trials and Phase II efficacy trials have yielded more positive data.3,4,5 Most of the studies on gum guggul have used relatively small numbers of subjects; this tends to make mainstream medical scientists reluctant about natural remedies. A large, well-publicized double-blind Gugulipid trial on 400 to 500 people would go a long way toward giving this herb the credibility it deserves.
Another effective natural solution for blood fat control that should be better known is a relative of pantothenic acid (vitamin B5). Pantethine is the active form of pantothenic acid in the body. Pantethine forms CoA, an essential co-enzyme for utilization of fat. CoA transports "active acetate," an important byproduct of fat metabolism that provides fuel for generating cellular energy. By promoting the burning of fats for energy, pantethine helps keep triglyceride levels down.6 Pantethine also helps regulate cholesterol production, by facilitating the conversion of fat into other lipid-based molecules needed in the body.6
Japanese researchers began studying the effect of pantethine on blood fats nearly twenty years ago. They reported their promising results at the Seventh International Symposium on Drugs Affecting Lipid Metabolism, held in Milan, Italy in 1980.7 Few in the medical or scientific communities took notice. Italian researchers followed up with several small clinical trials that confirmed the preliminary reports.6,8,9 An excellent cholesterol and triglyceride lowering agent that is safe and free of side-effects, pantethine remains, for the most part, ignored by mainstream science, although its usage is growing in alternative medicine circles. Pantethine it will no doubt prove to be one of the most important supplements for maintaining healthy blood fat levels.
When taken in high enough doses, niacin (vitamin B3) substantially lowers cholesterol. This has been known to medical science for many years.10 studies on niacin as a cholesterol-lowering agent go back to the 1950's. There was a fair amount of initial enthusiasm for niacin because it improves, unlike most lipid-lowering drugs, all parameters of the blood lipid profile. Niacin reduces total cholesterol, LDL cholesterol and triglycerides. It also raises HDL cholesterol quite well. Interest in niacin has faded, in part because the necessary dose, 1200 milligrams a day or more, can cause flushing and gastrointestinal disturbances. Very high doses may be harmful to the liver if taken for too long.
There is a solution to the side-effect problem with niacin which, again, has failed to gain widespread attention. Inositol hexanicotinate is a flush-free form of niacin composed of six niacin molecules bonded to one molecule of inositol, another B-complex nutrient. Absorbed as an intact structure, inositol hexanicotinate is metabolized slowly, releasing free niacin into the bloodstream over a period of hours following ingestion.11 Inositol hexanicotinate has all the benefits of niacin for controlling blood fats. The flushing effect of ordinary niacin, which metabolizes much more rapidly, does not occur. Taking as much as four grams per day has not been reported to raise liver enzymes or cause other side-effects, but prudence dictates that people with liver problems should avoid very high doses of inositol hexanicotinate, or any form of niacin.12
We often think of vitamin E as synonymous with d-alpha tocopherol. Vitamin E is actually a whole family of compounds that includes various tocopherols and a group of lesser known but highly beneficial substances called "tocotrienols." All have vitamin E activity. Tocotrienols are similar in chemical structure to tocopherols, but they have important differences which give them unique and highly beneficial properties for human health.
Vitamin E is one of the most recognized antioxidants, nutrients that deactivate potentially toxic byproducts of oxygen metabolism known as free radicals. Vitamin E neutralizes peroxides, which result from the free radical oxidation of lipids, making it a key antioxidant in cell membranes. While d-alpha tocopherol has generally been regarded as the form of vitamin E with the strongest antioxidant activity, tocotrienols are even stronger.
The tocotrienol story is another example of a natural product slow to gain recognition. A Univeristy of California research team discovered that d-alpha tocotrienol is over six times more effective than d-alpha tocopherol at protecting cell membranes against free radical damage.13 In the presence of vitamin C, which recycles vitamin E-like compounds, its antioxidant activity is 40 to 60 times higher than d-alpha tocopherol. This study was published in 1991. Its safe to say few cardiac physicians know about tocotrienols, and we have yet to see 60 Minutes do a piece on "the powerful new form of vitamin E."
It would be a tremendous service to public health if they did, because the benefits of tocotrienols go far beyond their stellar antioxidant ability. Tocotrienols also lower total cholesterol and LDL, by impressive percentages. In one double-blind controlled study, tocotrienols reduced total cholesterol by 16 percent and LDL by 21 percent after twelve weeks. Another study recorded drops of 15 to 22 percent in total cholesterol along with 10 to 20 percent decreases in LDL levels.14 Now appearing on health food store shelves, tocotrienols are a health-protecting nutrients whose long overdue time has come. Derived from food oils such as palm oil and rice bran oil, tocotrienols have the same lack of toxicity as ordinary vitamin E.
1. Satyavati, G. Gugulipid: a promising hypolipidaemic agent from gum guggul (Commiphora wightii). Economic and Medicinal Plant Research 1991;5:47-82.
2. Dev, S. A modern look at an age-old Ayurvedic drug—guggulu. Science Age July 1987:13-18.
3. Nityanand, S., Srivastava, J.S., Asthana, O.P. Clinical trials with gugulipid. J. Ass. Physicians of India 1989;37(5):323-28.
4. Agarwal, R.C. et. al. Clinical trial of gugulipid—a new hypolipidemic agent of plant origin in primary hyperlipidemia. Indian J Med Res 1986;84:626-34.
5. 'Gugulipid' Drugs of the Future 1988;13(7):618-619.
6. Maggi, G.C., Donati, C., Criscuoli, G. Pantethine: A physiological lipomodulating agent, in the treatment of hyperlipidemias. Current Therapeutic Research 1982;32(3):380-86.
7. Kimura, S., Furukawa, Y., Wakasugi, J. Effects of pantethine on the serum lipoprotiens in rats fed a high cholesterol diet (Abstract) Seventh International Symposium on Drugs Affecting Lipid Metabolism, Milan, Italy, 1980.
8. Arsenio, L. Bodria, P. Effectiveness of long-term treatment with pantethine in patients with dyslipidemia. Clinical Therapeutics 1986;8(5):537-45.
9. Avogaro, P. Bittolo Bon, G. Fusello, M. Effect of pantethine on lipids, lipoproteins and apolipoproteins in man. Current Therapeutic Research 1983;33(3):488-93.
10. Crouse, J.R. New developments in the use of niacin for treatment of hyperlipidemia: new considerations in the use of an old drug. Coronary Artery Disease 1996;7(4):321-26.
11. Welsh, A.L. Ede, M. Inositol hexanicotinate for improved nicotinic acid therapy. International Record of Food Medicine 1961;174(1):9-15.
12. "Inositol hexaniacinate" (Monograph). Alternative Medicine Review 1998;3(3):222-3.
13. Serbinova, E., et. al. Free radical recycling and intramembrane mobility in the antioxidant properties of alpha-tocopherol and alpha tocotrienol. Free Radical Biology and Medicine 1991;10:263-275.
14. Qureshi, N. Qureshi, A.A. Tocotrienols: Novel Hypercholesterolemic Agents with Antioxidant Properties. in 'Vitamin E in Health and Disease' Lester Packer and Jürgen Fuchs, Editors. 1993; New York: Marcel Dekker, Inc.
Control Cholesterol with the following Supplements
New Larger Size Red Yeast Rice with CoQ10 90ct
May 10, 2005 12:43 PM
red yeast rice Plus CoQ10 90ct
red yeast rice is manufactured by the fermentation of a strain of yeast, Monascus Purpureus, on rice and has been used traditionally by the Chinese as a flavoring and a good preservative. Because red yeast rice may reduce CoQ10 levels, it may be important to supplement with CoQ10 at the same time as red yeast rice and CoQ10.
Cholesterol-lowering effects of Chinese red-yeast-rice.
May 09, 2005 11:46 AM
Cholesterol-lowering effects of a proprietary Chinese red-yeast-rice dietary supplement.
Heber D, Yip I, Ashley JM, Elashoff DA, Elashoff RM, Go VL.
Center for Human Nutrition, Department of Medicine, UCLA School of Medicine, Los Angeles, CA 90095-1742, USA. email@example.com
BACKGROUND: We examined the cholesterol-lowering effects of a proprietary Chinese red-yeast-rice supplement in an American population consuming a diet similar to the American Heart Association Step I diet using a double-blind, placebo-controlled, prospectively randomized 12-wk controlled trial at a university research center. OBJECTIVE: We evaluated the lipid-lowering effects of this red-yeast-rice dietary supplement in US adults separate from effects of diet alone. DESIGN: Eighty-three healthy subjects (46 men and 37 women aged 34-78 y) with hyperlipidemia [total cholesterol, 5.28-8.74 mmol/L (204-338 mg/dL); LDL cholesterol, 3.31-7.16 mmol/L (128-277 mg/dL); triacylglycerol, 0.62-2.78 mmol/L (55-246 mg/dL); and HDL cholesterol 0.78-2.46 mmol/L (30-95 mg/dL)] who were not being treated with lipid-lowering drugs participated. Subjects were treated with red yeast rice (2.4 g/d) or placebo and instructed to consume a diet providing 30% of energy from fat, <10% from saturated fat, and <300 mg cholesterol daily. Main outcome measures were total cholesterol, total triacylglycerol, and HDL and LDL cholesterol measured at weeks 8, 9, 11, and 12. RESULTS: Total cholesterol concentrations decreased significantly between baseline and 8 wk in the red-yeast-rice-treated group compared with the placebo-treated group [(x+/-SD) 6.57+/-0.93 mmol/L (254+/-36 mg/dL) to 5.38+/-0.80 mmol/L (208+/-31 mg/dL); P < 0.001]. LDL cholesterol and total triacylglycerol were also reduced with the supplement. HDL cholesterol did not change significantly. CONCLUSIONS: red yeast rice significantly reduces total cholesterol, LDL cholesterol, and total triacylglycerol concentrations compared with placebo and provides a new, novel, food-based approach to lowering cholesterol in the general population.
Publication Types: Clinical Trial Randomized Controlled Trial
PMID: 9989685 [PubMed - indexed for MEDLINE]
May 09, 2005 11:35 AM
Red Yeast Rice can Lower Cholesterol. Scientific Studies prooven
May 09, 2005 11:33 AM
Department of Biochemical Pharmacology, School of Pharmaceutical Science, Peking University Health Science Center, Beijing 100083, China.
Long-term effects of Cholestin (Monascus purpureus rice; red yeast rice) on serum lipids and severity of atherosclerosis were examined in rabbits fed for 200 days on a semi-purified diet containing 0.25% cholesterol. Serum total cholesterol was 25 and 40% lower, respectively, in rabbits fed 0.4 or 1.35 g/kg/day of Cholestin (Monascus purpureus rice; red yeast rice) compared to controls. This treatment also lowered serum LDL cholesterol. This 200-day treatment significantly reduced serum triglycerides and atherosclerotic index (ratio of non-HDL-cholesterol to HDL-cholesterol). Although similar reductions of total, LDL-cholesterol and triglycerides were observed, a parallel group of rabbits fed lovastatin (0.0024 g/kg/day) failed to reduce the index significantly. Apolipoprotein A(1) was increased and apolipoprotein B was reduced in all treatment groups. Severity of atherosclerosis was reduced significantly in all treatment groups. The sudanophilic area of involvement was 80.6% in controls, and reduced significantly; to 30.1% on the low dose (Monascus purpureus rice; red yeast rice), and 17.2% on the high dose. Lovastatin reduced severity of lesions by 89% (sudanophilia) and 84% (visual). Visual grading of lesion severity showed reduction by 38% and 68%.
PMID: 12873712 [PubMed - indexed for MEDLINE]