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Study: Following a choline-rich diet may offer transgenerationalprotection against Alzheimer's disease Darrell Miller 4/24/19
Help mitigate the toxic effects of traditional cancer treatments with diet: Soy, cruciferous vegetables associated with fewer side effects Darrell Miller 1/4/18
Mice fed tryptophan develop immune cells that foster a tolerant gut Darrell Miller 8/13/17
5 Reasons you should NEVER use canola oil, even if its ORGANIC Darrell Miller 6/27/17
Daily consumption of tea protects the elderly from cognitive decline Darrell Miller 3/20/17
Cooking With Canola Releases More Toxic Cancer-Causing Chemicals Than Any Other Type of Oil Darrell Miller 3/14/17
Diabetes control: Warning signs and tips to reduce your risk Darrell Miller 3/5/17
Are your storable foods mostly just reprocessed GMO corn? Darrell Miller 12/8/16
Say NO to GMO in America Darrell Miller 12/5/16
Gene-editing techniques used in humans for first time Darrell Miller 11/29/16
Is your storable food just repackaged genetically modified SOY and CORN? Darrell Miller 11/15/16
A metabolic switch to turn off obesity Darrell Miller 11/1/16
Through Epigenetics, Curcumin Can Stop Cancer Darrell Miller 8/20/16
One plants broad based attack against cancer Darrell Miller 8/16/16
What Is GMO and Why Should We Avoid It? Darrell Miller 6/21/14
How Does Serrapeptidase Support A Healthy Immune System, Regulate Inflammation, And More? Darrell Miller 9/1/11
Avage Nectar Facts Darrell Miller 4/8/10
NADH 10 mg And 20 mg Enhanced with Bioenergy RIBOSE Darrell Miller 12/10/09
GrapeSeed Extract Darrell Miller 10/15/08
Ester-E Darrell Miller 6/7/08
Gently Narrow Your "Estrogen Window" With Lignan's Darrell Miller 1/25/08
Revita Darrell Miller 3/8/07
Dr. Nugent’s Genetic Key Diet Notes Why is America Losing the Fat Battle? Darrell Miller 9/19/06
How to deal with Stress and Cortisol... Darrell Miller 8/30/06
Setting the Record Straight on Vitamin E Darrell Miller 8/4/06
The True Whey, boost your immune system Darrell Miller 4/29/06
New Frontiers in Enzyme Supplementation Darrell Miller 2/16/06
Omega man Darrell Miller 1/21/06
Vitamin C FAQ's Darrell Miller 12/27/05
Nattokinase Fact Sheet Darrell Miller 12/8/05
Tru-E Bio Complex Darrell Miller 12/8/05
NOW is the leader in quality and value Darrell Miller 10/21/05
Results of GM Foods... Darrell Miller 10/18/05
Maintaining Healthy Veins Darrell Miller 7/25/05
Nature's Cancer fighters ... Darrell Miller 7/7/05
REFERENCES Darrell Miller 6/25/05
Fats and Oils: Clearing the Confusion Darrell Miller 6/21/05
Certified Foods Darrell Miller 6/12/05
Heart Science - A Five-Tiered Approach to Heart Health ... Darrell Miller 6/2/05
Re: Its in the Blood Darrell Miller 5/9/05




Study: Following a choline-rich diet may offer transgenerationalprotection against Alzheimer's disease
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Date: April 24, 2019 03:44 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Study: Following a choline-rich diet may offer transgenerationalprotection against Alzheimer's disease





Lack of nutrition can end up damaging cells and bring out the worst traits in our genes. A new study found that a maternal high diet in choline can protect the offspring from getting Alzheimer's disease in the future even if the choline levels in the offspring are low. The study was done on mice that were genetically predisposed to Alzheimer's. The body makes choline naturally, but some needs to be consumed in order to receive the amount that is required for healthy cellular functions.

Key Takeaways:

  • The nutrients that we take are like instructions to the body that build up our cells and tell them how to operate and communicate.
  • The benefits of nutritional instructions to the body is to strengthen our genetics and prevent diseases, while a lack initiates changes in our genes and cause diseases.
  • It has been shown from research that nutritional instructions when taken by the mother can be passed on to generations through the genetic code.

"The mice that were born from mothers on choline-rich diets developed fewer disease-associated brain changes. They also exhibited improved memory skills. Even when the descendants didn’t receive choline in their diet, they still enjoyed the benefits of brain protection from their mother’s nutrient-rich diet."

Read more: https://www.naturalnews.com/2019-03-11-study-following-a-choline-rich-diet-protection-against-alzheimers-disease.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6179)


Help mitigate the toxic effects of traditional cancer treatments with diet: Soy, cruciferous vegetables associated with fewer side effects
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Date: January 04, 2018 07:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Help mitigate the toxic effects of traditional cancer treatments with diet: Soy, cruciferous vegetables associated with fewer side effects





Food may be a great way to help you fight cancer. A recent study has shown that eating more cruciferous vegetables, like broccoli and kale, as well as soy can help breast cancer survivors as well as menopause sufferers. The study found that the symptoms of both were decreased with a diet higher in these nutrients. Oddly they only found this with in Caucasians. Asian women were shown to have no effect from this diet, leading the researchers to have more questions about the exact pathway.

Key Takeaways:

  • A large study found a link between cruciferous vegetable and soy to fighting breast cancer
  • The study found that the effect was greater in caucasians over Asian women
  • The link is unclear and they need to do more studies to see why it is isn't as positive for all groups.

"Choosing organic soy products is the easiest way to avoid genetically modified soy."

Read more: https://www.naturalnews.com/2017-12-28-help-mitigate-the-toxic-effects-of-traditional-cancer-treatments-with-diet-soy-cruciferous.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5479)


Mice fed tryptophan develop immune cells that foster a tolerant gut
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Date: August 13, 2017 09:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Mice fed tryptophan develop immune cells that foster a tolerant gut





Tryptophan is a fundamental building block of protein. A study was conducted on genetically identical mice that were separated and raised in different environments, which led to the finding that environmental factors were a high contributor in regards to developing an immunity to irritable bowel disease. Bacteria highly affects the immune system because the mice that were raised in sterile conditions grew the immune cells. Doctor Luisa Cervantes-Barragan conducted the study. Tryptophan is common in both mouse and the human balanced food diet.

Key Takeaways:

  • Tryptophan ingestion in mice leads to formation of micros that fight IBS
  • Humans suffering from IBS can benefit diets high in tryptophan
  • Foods high in protein such as eggs , chocolate, and cheese have these compounds.

"People have the same tolerance-promoting cells as mice, and most of us shelter L. reuteri in our gastrointestinal tracts."

Read more: https://medicalxpress.com/news/2017-08-mice-fed-tryptophan-immune-cells.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5119)


5 Reasons you should NEVER use canola oil, even if its ORGANIC
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Date: June 27, 2017 09:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: 5 Reasons you should NEVER use canola oil, even if its ORGANIC





Canola oil is a popular cooking oil that is attractive to customers and the restaurant industry. Canola oil is believed to have benefits such as a smaller waistline and a cleaner environment. It is now believed that Canola oil may not be as healthy as once thought. Canola oil must undergo many chemical processes in its original form before it can be converted into Canola oil. Also, since the Canola plant is one of the first plants that was genetically modified, it may be subject to exposure by a large amount of pesticides.

Key Takeaways:

  • Even though canola oil has been viewed as "healthy", it's not as healthy as we think
  • The process to manufacture canola oil is quite lengthy and completely changes the original product
  • While some believe it aids in cardiovascular health, studies show this may not be true

"Even canola oils deemed organic still undergo various production processes, and may not have a healthier fatty acid profile compared with commercial varieties."

Read more: http://www.naturalnews.com/2017-06-24-6-reasons-you-should-never-use-canola-oil-even-if-its-organic.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4890)


Daily consumption of tea protects the elderly from cognitive decline
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Date: March 20, 2017 03:44 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Daily consumption of tea protects the elderly from cognitive decline





The daily consumption of tea protects elderly people from cognitive decline. It reduces the decline by 50 percent and as much as 86 percent for people who have a genetic risk for Alzheimer's disease. New research has come to this conclusion. The saying is that a cup of tea a day can help keep dementia away.

Key Takeaways:

  • A cup of tea a day can keep dementia away, and this is especially so for those who are genetically predisposed to the debilitating disease.
  • The neuroprotective role on cognitive function is not limited to a particular type of tea -- so long as the tea is brewed from tea leaves, such as green, black or oolong tea.
  • The tea compounds exhibit anti-inflammatory and antioxidant potential and other bioactive properties that may protect the brain from vascular damage and neurodegeneration.

""A cup of tea a day can keep dementia away...""



Reference:

https://www.sciencedaily.com/releases/2017/03/170316093412.htm

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4241)


Cooking With Canola Releases More Toxic Cancer-Causing Chemicals Than Any Other Type of Oil
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Date: March 14, 2017 01:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Cooking With Canola Releases More Toxic Cancer-Causing Chemicals Than Any Other Type of Oil





Canola oil is extracted from rapeseed and despite claims that it's healthy, it's actually the worst type of oil you can use. Most canola oil is made from genetically modified crops and the modification actually increases risks to health including causing cancer. Oil made from rapeseed used to be used as an industrial lubricant and canola can be used as a pesticide. It's important to also know that the oil is hydrogenated and can cause cardiac risks.

Key Takeaways:

  • All cooking oils (other than “cold pressed” or “extra virgin” oils) are refined. This process typically includes degumming; bleaching and deodorizing.
  • Canola oil actually comes from rapeseed, and in the past it was simply known as rapeseed oil. At that stage, rapeseed oil was not used in the food industry.
  • In a nutshell, healthy living and canola oil simply don’t mix. There are far better options available, including organic extra virgin olive oil; organic cold pressed coconut oil, etc.

"In a nutshell, healthy living and canola oil simply don’t go well together."



Reference:

//www.healthnutnews.com/cooking-canola-releases-toxic-cancer-causing-chemicals-type-oil/

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4148)


Diabetes control: Warning signs and tips to reduce your risk
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Date: March 05, 2017 05:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Diabetes control: Warning signs and tips to reduce your risk





When you know the warning signs of diabetes, you can fight back against this debilitating condition that so many men and women are struggling with today. You can control your risk with the tips and information found here. Are you ready to learn how to protect yourself?

Key Takeaways:

  • Educating ourselves on chronic diseases that are significant risks to our health can significantly improve and even save our lives.
  • Although we may worry about genetically modified foods and pesticide contamination, diabetes is a greater risk to your health and well being.
  • Diabetes is a disorder of insulin production or use. Insulin is secreted by the pancreas in response to the food we consume.

"Exercise is also critical as it makes the body more sensitive to the effects of insulin. It can reduce body fat if calories are controlled."



Reference:

https://www.google.com/url?rct=j&sa=t&url=https://blogs.bcm.edu/2017/02/27/diabetes-control-warning-signs-and-tips-to-reduce-your-risk/&ct=ga&cd=CAIyGjBhMmIxOTgxN2IyMDM3NjI6Y29tOmVuOlVT&usg=AFQjCNG34rBCJoMdTu9CudQuENT8XC2aqg

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4074)


Are your storable foods mostly just reprocessed GMO corn?
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Date: December 08, 2016 08:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Are your storable foods mostly just reprocessed GMO corn?





Stocking up on non-perishable foods seems like an intelligent concept on the surface. But upon closer examination, it may prove that they stored food you buy contains genetically-modified organisms and additives that are toxic to your system. Transgenic corn, corn startch and high-fructose corn syrup are widely used in storable foods, but are nto organic products and are derivatives of "Frankencrops." Many popular brands that sell packaged food use these subtances to increae the shelf life of the food, but the presence of these chemicals in concerning.

Key Takeaways:

  • many people are preparing in advance by stocking up on storable food supplies to back end any potential hiccups in the supply chain. But it's important to remember that not all storable food is the same, and that much of it is actually loaded with things you probably wouldn't want to feed your families – things like genetically-modified organisms (GMOs) and toxic food additives.
  • If you're someone who's already purchased storable food, you might want to take a closer look at the ingredients list to determine whether or not you've made the right choice. If you haven't yet purchased storable food but are interested in doing so, there are excellent options like Numanna Organic Survival Food that are both free of these offending ingredients and surprisingly healthy and nutritious.
  • Wise Food Storage brands itself as having the highest quality survival food on the market. But a quick look at the ingredients lists for the products contained in its "1 Month Emergency Supply of Food and Drinks" reveals much of the same

"not all storable food is the same, and that much of it is actually loaded with things you probably wouldn't want to feed your families"



Reference:

//www.naturalnews.com/056114_emergency_food_preppers_GMO_corn.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3596)


Say NO to GMO in America
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Date: December 05, 2016 10:18 PM
Author: Darrell Miller
Subject: Say NO to GMO in America

Coming from over 50 countries, countless millions of people have expressed their disapproval over attempted corporate ownership of plant seeds through GMO (genetically modified organisms). Having said that, the corporations involved have assured the public that GMO is safe and want us to believe that it's more efficient at feeding the world by giving higher yields and have greater resistance to extreme weather conditions.

Safety of GMO

According to a growing number of scientists such as world leading expert Dr Don Huber GMO expert, professor of plant pathology at Purdue University, Lafayette, Indiana, USA, there has been NO peer reviewed evidence to support the idea that GMO crops are safe. On the contrary, a vast catalogue of scientific evidence has built up over the years showing that GMO is unsafe. 

Public consumption of genetically modified crops have been accused of causing ill health in the form of allergies, cancer, birth defects and infertility. It also includes toxicity, reduced nutritional value, environmental damage and political unrest such as that with farmer's and consumer's disputes.

The Revolving Door Effect

Approval bodies like the FDA (Food and Drug Administration) decide whether or not a food or drug is fit to go out on the market for consumption.  GMO is not safe. Nor has it shown to produce higher yield, greater nutritional value or resist drought conditions better than non-GMO according to many experts such as Professor John Fagan, award-winning Geneticist, Maharishi University of Management, Iowa, USA.

Yes, of course we should say NO to GMO. It is spurred on by corporate greed and political self interest with more than its fair share of hidden ulterior motives. The technology is unimaginably potentially dangerous and could be perceived as one of the biggest threats to humanity if allowed to get out of control.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3577)


Gene-editing techniques used in humans for first time
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Date: November 29, 2016 08:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Gene-editing techniques used in humans for first time





China has become the first country to genetically modify genes and insert them back into a human body. The test patient is suffering from aggressive lung cancer. They were able to extract genes that they believe will effectively attack the cancer if they are in high enough numbers. No final results have been released on the study, but it is a huge milestone in the research field. China is not the only country working on the technology, and the first to complete it would be looking at huge profits.

Key Takeaways:

  • The technique knocks out a gene that normally acts as a check on the cell's ability to launch an immune response and prevents it from attacking healthy cells.
  • The modified cells were then multiplied and re-introduced into the patients' bloodstream where, it is hoped, they will home in on the cancer and wipe it out.
  • He said information on the results and findings of the study would be released when they are ready.

"The modified cells were then multiplied and re-introduced into the patients' bloodstream where, it is hoped, they will home in on the cancer and wipe it out."



Reference:

//www.cnn.com/2016/11/15/health/china-human-gene-testing-crispr-cas9/index.html?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+rss%2Fcnn_health+%28RSS%3A+CNN+-+Health%29

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3530)


Is your storable food just repackaged genetically modified SOY and CORN?
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Date: November 15, 2016 12:54 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Is your storable food just repackaged genetically modified SOY and CORN?





Common survival and storable foods are may not be the healthiest foods to keep for long term health. It seems that many of these foods are loaded with unhealthy additions like MSG and pesticides. Almost all of these products contain corn and soybean in one form or another and most of those crops are genetically modified. Luckily, there are some healthier alternatives out there that don’t contain such toxic ingredients.

Key Takeaways:

  • Mike Adams, the Health Ranger, reported on the presence of toxic ingredients in many survival foods
  • Adams wrote that nearly every popular storable food product contained GMOs
  • Genetically modified corn and soy are two of the most prolific ingredients on the food market today

"Last week, Mike Adams, the Health Ranger, reported on the presence of toxic ingredients in many survival foods. Adams wrote that nearly every popular storable food product contained GMOs, pesticides, and monosodium glutamate (MSG.)"



Reference:

//www.naturalnews.com/055904_survival_foods_clean_ingredients_organic.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3448)


A metabolic switch to turn off obesity
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Date: November 01, 2016 04:04 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: A metabolic switch to turn off obesity

Here’s some good news to cheer you up. If you’ve been fighting a losing battle trying to lose weight, maybe you should quit beating yourself up about it. A new University of Montreal study of mice says when an enzyme is blocked in some neurons in the mouse brain, it becomes impossible for the mice to lose weight even when they stick to an ideal regime. So now you can blame it all on the ABHD6 enzyme.

Key Takeaways:

  • A research team at the University of Montreal Hospital Research Centre (CRCHUM) has generated genetically engineered mice
  • The researchers have discovered that this enzyme acts as a sort of switch for the body's adjustment to extremes.
  • In 2014, the team of Marc Prentki, another CRCHUM researcher, discovered that this enzyme breaks down endocannabinoids.

"A research team at the University of Montreal Hospital Research Centre (CRCHUM) has generated genetically engineered mice, deprived of the ABHD6 enzyme in a localized area of the brain, namely in a specific population of hypothalamic neurons."



Reference:

https://www.sciencedaily.com/releases/2016/10/161027115843.htm

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3368)


Through Epigenetics, Curcumin Can Stop Cancer
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Date: August 20, 2016 10:28 AM
Author: Darrell Miller
Subject: Through Epigenetics, Curcumin Can Stop Cancer

Epigenetics: In a nutshell, the way we eat turns on and turns off various genes in the body. Depending on your diet, you can turn on cancer preventative genes and turn on genes that promote cancer.

Curcumin is able to tell those apoptosis inducing genes to wake up and end the lives of cancer cells that are defying death. Curcumin can selectively kill cells that have out lived their lifespan with out hurting other normal cells in the body. It reprograms genetically damaged cells to have a normal lifespan.

All of the healing properties of curcumin happen with zero side effects, unlike prescription drugs that your doctor prescribe, that no only have side effects, some of these side effects can be life threatening. Who wants that? Not Me!

If you have cancer, or any disease for that matter, try curcumin as a complementary supplement to what ever you are currently doing to fight it, or take curcumin as a preventative!

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3258)


One plants broad based attack against cancer
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Date: August 16, 2016 02:41 PM
Author: Darrell Miller
Subject: One plants broad based attack against cancer

There are a multitude of ways cancer cells can form,  lets look at a few ways and discuss them.

Epigenetics: A process that controls the behavior of genes.  Dietary and lifestyle choices can alter the way our genes work. Exposure to toxins can cause protective genes to goto sleep and allow destructive genes to awaken all due to the way we eat and live.  When this happens, disease can start.

Apoptosis: known as the programed life cycle of cells.  this natural cycle can be interrupted and when this happens, the cell does not die as intended, old and genetically damaged cells form tumors.

Angiogenesis: damaged cancer cells need nutrients and oxygen to survive.  Some cancers are able to form their own network of blood vessels.

Cancer Stem Cells: these are super cancer cells that can remain dormant for years which eventually activate and causes cancer to recur.

Cancer is a very complex disease, todays anti-cancer drugs are designed to address only one single pathway or gene with in cancer cells.  Since cancer is a complex network of hundreds of genes and pathways, conventional drugs are very unlikely to be effective in the end. 

Since a large majority of the drugs are designed around natural plants and their function, it would stand to reason that taking the natural plant would not only be effective but have zero side effects. 

Fortunately, we have a plant that has been validated by thousands of scientific studies.  This plant compound is called curcumin. 

  • Curcumin has shown positive results for virtually every disease it has been research and studied.
  • Curcumin is a strong anti-inflammatory plant and is also a strong antioxidant actually the highest of any food gram for gram.
  • Curcumin's anti-cancer properties make it unique and make it the ideal plant compound to conquer literally every type of cancer and many other chronic diseases.
  • Curcumin attacks cancer from many directions known as multi-targeting, making it more effective than drugs that are currently being used.
  • Preventative treatment is also preferable.  A healthy diet and lifestyle are scientifically proven to prevent and reduce cancer.  Curcumin should be one plant compound everybody should be consuming to prevent cancer and many other disease.
  • Curcumin can be used in conjunction with conventional medicine to further boost healing in individuals who suffer from various diseases.

If you are somebody you know is suffering from cancer, you should seriously consider taking curcumin or telling family members about this wonderful plant compound.




(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3256)


What Is GMO and Why Should We Avoid It?
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Date: June 21, 2014 02:40 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Is GMO and Why Should We Avoid It?

Cause of GMO

gmoGMO's have been classified by the American Academy of Environmental Medicine as unhealthy, they were able to prove that GMO when ingested can cause organ damage, gastrointestinal as well as immune system disorders. This is due to the fact that GMO contains materials that are left behind the body, it can cause long term problems like accelerated aging as well as infertility. The genes inserted into a genetically modified crop like corn, can get transferred into the DNA of bacteria that is living inside the human body, this interaction can lead to a number of long term health problems.

Negative effects of genetically modified products have been observed in 1996, this was due to the number of Americans expressing a number of illnesses after consuming foods that have been engineered for 9 years.

Allergies increased including digestive problems and autism, while other research has yet to support this claim, many non-profit organizations such as Greenpeace are already making campaigns against the production of GMO infused crops and meat.

What are the other negative impacts of GMO?

1. Cancer causing components - GMO according to the American Public Health Association and American Nurses Association, have stated that the growth hormone present from cow’s milk treated by hormone IGF-1 can lead to cancer.

2. Long term negative effects on the body - GMO components can contaminate forever, it can cross pollinate, and the seeds can travel. Once it infects a certain area, it can contaminate the entire gene pool. This means, that the health of future generations is already compromised and for this reason, the production has to be stopped right away before it infects more population.

3. Dangerous side effects - the mere process of creation of GMO's can produce toxins, carcinogens, allergens and nutritional deficiencies.

The direct production and consumption is already endangering a number of species including bees.

Many governments continue to remain lax about the issue, GMOs are illegally being sold and created in many countries, and people need to learn as much as they can in order to learn how they can prevent GMO products from entering their market.

Sources

//www.responsibletechnology.org/10-Reasons-to-Avoid-GMOs

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3138)


How Does Serrapeptidase Support A Healthy Immune System, Regulate Inflammation, And More?
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Date: September 01, 2011 02:25 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How Does Serrapeptidase Support A Healthy Immune System, Regulate Inflammation, And More?

What Does Serrapeptidase Do In The Body?

Serrapeptidase is an enzyme which is protein - digesting by nature. It is considered to be one of the types of proteolytic enzymes which consist of the chemical substance protease. This chemical is derived from a non - genetically engineered fungus of the family of Aspergillus. Serrapeptidase is a dietary supplement which may be isolated from Serrapeptidase oryzae and Serrapeptidase melleus. Studies have claimed that this dietary supplement is effective as an anti - inflammatory, respiratory aid, cardiovascular or immune support. Other names of Serrapeptidase include serration - peptidase and serrapeptase.

During the early 1990’s, Serrapeptidase was isolated from the microorganism Serratia marcescens which is a known human pathogen found in the digestive tract of the Japanese silkworm. Many studies have been conducted to uncover the medicinal purposes of this bacterial enzyme. In fact, it has been widely used clinically in specific areas of Asia and Europe primarily as an inflammation relief agent.

These are some of the uses of the enzyme Serrapeptidase:

1. ANTI – THROMBIC AND FIBRINOLYTIC. Serrapeptidase can significantly prevent the build – up of blood clots. These clots must not be accumulated to prevent thromboembolism which can cause life threatening health conditions such as heart attack and stroke. Aside from its ability to prevent clot formation, Serrapeptidase also has a good fibrinolytic ability. It can lyse or dissolve already – formed blood clots.

2. PH REGULATOR. This proteolytic enzyme is considered to be an alkaline metalloprotease enzyme. It can selectively act on specific biological systems and prevent the activation of immunoglobulin G and immunoglobulin A. These body chemicals are immune system factors which helps the body prevent from infections and illnesses.

3. GOOD PROTEIN DIGESTER. Clinical studies have revealed that Serrapeptidase has a very good ability to digest protein molecules and its substrates. This is the reason behind why Serrapeptidase can effectively dissolve protein – based tissues such as fibrins, blood clots, cysts and certain inflammations. The advantage of this enzyme is that it can dissolve unnecessary tissues without harming the normal living tissues.

4. PROFOUND ANTI – INFLAMMATIORY AGENT. Serrapeptidase can effectively prevent and reduce inflammation, thus reducing swelling and pain sensation. The mechanism of action is said to be that Serrapeptidase blocks the synthesis of pain – inducing amines. Another mechanism is that it can effectively inactivate pro – inflammatory chemicals known as cytokines. In fact, this chemical is one of the components of analgesic drugs in Europe. The positive effect of this enzyme is that it does not have any digestive side effects.

5. RESPIRATORY AID. This enzyme is also helpful in improving the health of the respiratory system. It effectively alters the elasticity and viscosity of the dense mucus in people with respiratory problem such as sinusitis, bronchitis, asthma, and pulmonary diseases. People who are taking this enzyme supplement have shown improved liquefaction and expectoration of the mucus, thus Serrapeptidase is considered to be an effective mucolytic agent widely used all over the world.

Serrapeptidase is generally safe. Clinical studies have revealed that the sources of this enzyme are non – pathogenic except of one strain known as Serratia marcesens. This strain is pathogenic to human body. It may cause hypersensitivity or any untoward signs and symptoms. Therefore, it is best to consult a doctor before starting such supplementation.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2414)


Avage Nectar Facts
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Date: April 08, 2010 04:02 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Avage Nectar Facts

First of all let me preface by saying thank you very much for contacting Madhava Honey with your concern. Madhava has been in business for over 36 years and one of our four fundamental core values is and always will be to provide the Highest Quality product that exceeds the industry standard. Our other three core values are providing a product with the highest respect to the environment and health of the consumer, supporting community development via living wages and sustainable development of local economies, and finally providing a fair guaranteed price for our suppliers. Thirty six years ago Madhava was founded on "sustainable" practices and we take negative misleading attacks on our products very seriously. Madhava will try to respond to all the issues in question along with providing a little bit of background information on the source of the attacks. Finally at Madhava we believe in full transparency and please do not hesitate to contact us directly if you feel any questions or concerns have not been addressed. Thank you very much.

A. What constitutes Madhava's Agave Nectar?

There are 3 main components of our Agave Nectar. It is naturally composed primarily of the simple sugars fructose, glucose (dextrose), and water. Madhava’s Agave is Certified Organic and is Genetically Modified Organism (GMO) Free.

B. How is Madhava's Agave Nectar produced?

The Agave plant is truly a remarkable plant! It grows in the harshest environments with little water and no upkeep is needed. It is naturally found in Western Mexico making it a non-evasive plant to the area regarding its growth and harvest. It requires no pesticides or fertilizers and is actually a cornerstone to its ecosystem. The Agave plant is truly a sustainably grown/harvested crop.

The Agave plant is grown for 6-8 years, then before turning to seed, it is then harvested by hand. Jimadores or Agave harvesters go to the selected fields and remove the "Pina" or heart of the Agave plant, by cutting off the long spiny "leaves" and unearthing it from the soil. It is all done by hand thus reducing the carbon footprint during harvesting. The Pinas are then loaded to a truck which takes them back to the harvesting facility.

There are two methods of making the Agave Nectar from the juice of the plant. One uses a natural non-GMO enzyme and the second uses thermal hydrolysis. Both processes achieve the same goal; which is to separate the naturally occurring Fructans, which are complex sugar molecules into their simple sugar components fructose and glucose.

The actual process of hydrolysis of agave, either thermal or enzymatic, is unlike the process of High Fructose Corn Syrup (HFCS), which creates fructose out of the glucose made from the milled starch of corn. Agave Nectar simply separates Fructans or Inulin, a complex naturally occurring sugar, into Fructose and Glucose.

C. Moderation vs. Overconsumption

It is certainly true that overconsumption of any one or a combination of sugars can have detrimental effects, but this is not in a vacuum, it involves lifestyles, other food choices and other conditions. Overconsumption of any food or beverage will have ramifications. Sweeteners are ingredients which are added to foods in relatively small quantity to make them more palatable. In others, sugars can make up a large portion of the caloric value. These foods are easy to identify and avoid as necessary. People do not consume sweeteners as a solitary food in mass quantity. They are just part of the choices people make and consumption can be controlled, each of us chooses what we eat and how much. There are no health issues with moderate consumption of sweeteners; every negative circulating is relative to the overall consumption of one's diet.

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NADH 10 mg And 20 mg Enhanced with Bioenergy RIBOSE
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Date: December 10, 2009 04:23 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: NADH 10 mg And 20 mg Enhanced with Bioenergy RIBOSE

NADH 10 mg And 20 mg Enhanced with Bioenergy RIBOSE™

NADH is the biologically-active form of vitamin B-3 (niacin), and is involved in a wide range of functions throughout the body. An easier way to understand it, is to think of NADH as a biological spark plug that makes it possible for us to become and remain energetic, active, and functioning at our best. Remove the “spark” and some of the most basic human functions will inevitably suffer. This is not speculation. It is the result of decades of scientific investigation that has examined the link between nutrition and chronic conditions; notably those related to cellular life cycles and apoptosis, excessive fatigue, enzyme decline, free radical expansion, cognitive disparity, intracellular balance, normalized aging, and many more important aspects of human health.*

Based on a wealth of ongoing studies, we have a great understanding of the benefits of NADH. Not only is it an effective source of cellular energy, it is also one the body’s versatile electron donors—the molecule most frequently degraded during oxidation. Because of these characteristics NADH is, however, also very unstable with regard to light and oxygen, which leads to a very rapid loss of overall effectiveness. Additionally, poor lifestyle choices, such as the use of tobacco, excessive consumption of alcohol, drugs, and prescription medications, sleep deprivation, genetically-engineered foods, and a host of others can all inhibit the activity of NADH within the body. Hope is not lost, however.

NOW® NADH contains a patented form of NADH from Panmol® - the first natural stabilized, stomach acidresistant form of this unique vitamin B3 supplement. Panmol® uses a patented process to naturally preserve its effectiveness. The end result is a highly stable, and bioavailable NADH which can easily withstand the harsh, acidic environment of the stomach and digestive tract; a breakthrough in the battle against many of todays’ most chronic conditions. NOW® NADH is available in both 10 and 20 mg potencies. Both varieties have been further enhanced with 200 mg of Bioenergy RIBOSE™ to support its cellular energy support properties.*

Who Stands to Benefit from NADH

With a proper supply of amino acids and/or B3 vitamins (niacin) the human body is, in fact, capable of producing a limited reserve of NADH. Under chronic strain however, the body’s need for NADH increases. As we age, the body’s ability to manufacture NADH becomes increasingly limited. With this in mind, the following groups stand to benefit the most from incorporating NOW® NADH into their supplement regimen.

• Those who work in stressful, cognitively-demanding professions
• Individuals who frequently struggle with fatigue
• People who have difficultly focusing on routine tasks
• Older and elderly individuals
• Those who want to maintain a high level of mental alertness
• Professionals who travel extensively for business
• Those who experience jet-lag after long flights

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GrapeSeed Extract
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Date: October 15, 2008 09:46 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: GrapeSeed Extract


It is possible to fight off aging with grape seed extract due largely to the antioxidant effect of the phytochemicals contained within the seed of the grape. The seed is rarely absorbed by your body because it is so difficult for your digestive juices to break down; significantly more difficult than the skin or the pulp. So what is specific about the seed that makes it so useful as a source of antioxidants? That shall be discuss shortly, but for now let's discuss the causes of aging, and how antioxidants can help to keep them at bay.

To fight off aging you have to understand what causes it, and the take steps to avoid these causes. It is fairly obvious that all causes of aging cannot be circumvented, but there are things that can be done to keep some of them at bay. Here, we are specifically concerned with the aging of your skin, which is the most visible form of aging. The first aspect of aging to understand is that there are two types: intrinsic and extrinsic.

Intrinsic Aging

Intrinsic aging is natural aging, and is largely genetic. Starting when you are fairly young, normally in the early to mid 20s, intrinsic aging is typified by wrinkling, hair loss or graying of the hair, hollowing of cheeks and other areas where the fat underneath the skin that normally contributes to your physical appearance is lost, and also bone loss that causes your skin to sag due a gradual loss of the structure that sculpts your physical appearance.

The age at which this occurs, and its speed is determined by your genes; although the process generally begins around the mid 20s, the speed with which it progresses is genetically controlled.

Extrinsic Aging

This is where grape seed extract can help. Extrinsic aging is not genetic, but environmental. Ten majority of this type of aging is due to exposure to the damaging UV light of the sun, which cause the typical 'leathery' look of the skin of people raised in areas such locations as the hotter parts of Australia and the USA, without the benefit of the native skin pigmentation that filters out these harmful ultra-violet rays.

Other factors that can cause the same degradation of your skin cells are smoking, the way you sleep and gravity. The sun generates free radicals (more on these later) that can destroy skin cells, cause freckles, leathery skin and a blotched complexion and also skin cancer. Smokers are more likely to develop leathery and wrinkled skin than non-smokers, and as the elasticity of your skin reduces, gravity cause jowls to develop and also a more pronounced lower lip.

Even your sleeping position can make you appear to age quicker, particularly using the same sleeping position on your pillow each night that cause what are known as sleep lines, that are really wrinkles that are difficult, if not impossible to remove. However, one of the most relevant factors is pollution, and the effects of car emissions, pesticides and other agricultural chemicals, paint fumes and 1001 other forms of chemical pollution that produce free radicals.

Where grape seed extract is involved in fighting off aging is in extrinsic aging is by destroying the free radicals. All substances, from the air to the oceans, are formed of atoms that contain electrons. Stable molecules contain an even number of electrons, or what are known as 'electron pairs'. When a molecule loses one electron it is known as a free radical, whose prime purpose in its very short life is to steal an electron from the nearest molecule. This 'short' lifetime can as long as a day or as short as thousandth of a second: it depends on is size and the degree of steric hindrance to the reaction with the spare electron.

Now that the reasons for aging and the nature of free radicals are better understood it is easier for you understand why grape seed extract can help to fight aging caused by the effects of free radicals on your skin.

Grape seed is a waste product of the wine industry. You cannot make wine from grape seeds, so they are removed from the final product by filtration or sedimentation. It contains a large number of phytonutrients, the most important being polyphenols in the form of flavanoids, lipids and carbohydrates. It also contains proteins that don't have much of an effect on aging. Flavonoids (also spelled flavanoids) are powerful antioxidants that destroy free radicals; they are twenty times as powerful as Vitamin E and over fifty times more powerful an antioxidant than Vitamin C.

Both of these vitamins are regarded as strong antioxidants in their own right, which is an indication of how good grape seed extract is at killing free radicals. It's like a combination of Harry Callahan, Paul Kersey, John McClane and the whole of the Magnificent Seven after the scavengers in your body cells. They succeed, and do it in spades!

Not only do the ingredients of grape seed extract kill off free radicals with the efficiency of a Delta Task Force, but are also anti-allergenic, anti-inflammatory, anti-cancer and anti just about anything else you can think of. However, let's have an even closer look and find out exactly what polyphenols are present in this so-called wonder juice.

Procyanadin was originally named Vitamin P in 1936 by its discoverer, Prof. Jacques Masquelier, and is believed to bond with collagen to protect you from premature aging by retaining and even improving the elasticity of your skin. An added benefit is that it also improves the elasticity of your blood vessels, and so helps to fight off the effects of high blood pressure and places less strain on your heart. The overall effect on your face is to practically give you a chemical face lift and also provide protection from the damaging effect of the UV component of sunlight through its lethal attitude towards the free radicals that UV radiation generates.

Another component of grape seed extract particularly that of muscadine grapes is resveratrol; a phytoalexin that has strong anti-inflammatory properties and can also fight off the effects of aging. Phytoalexins are antibiotics produced by plants that are under attack, and, in addition to helping you age slower, confers other benefits to your body including helping your brain to carry out its work more efficiently.

All in all, grape seed extract confers many benefits to your health and is also believed to possess powerful anti-cancer properties. However, it is for its ability to fight off aging that most people use it as a supplement, and in this respect it has been found to be extremely effective. Any antioxidant is of benefit to your body, but grape seed extract is of particular benefit due its high antioxidant potency.


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Buy Grape Seed Extract

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Ester-E
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Date: June 07, 2008 09:40 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Ester-E

Vitamin E is a known natural supplement and antioxidant that helps support the immune and cardiovascular systems. It is created by a natural process so that you can receive the purest form available. It is formed when natural d-alpha tocopherol is combined with a phosphate molecule. This combination protects the potency of Vitamin E until your body needs it the most.

Ester E is processed so that its natural benefits are preserved to give the body the most optimal benefit possible. This is why Ester E is the best form of Vitamin E available. Vitamin E is known to aid in the following actions:

* Preventing Alzheimer’s disease
* Reducing vision problems
* Preventing heart problems
* Protecting cell membranes
* Flushing LDL cholesterol

Vitamin E Food Sources:

* Nuts
* Oils
* Whole grains
* Spinach
* Asparagus
* Avocado
* Carrots
* Celery
* Apples
* Beef
* Seafood

How Vitamin E Works:

Manufacturers suggest that Ester E be taken along with a meal that includes some form of fat. This is because when fat is combined with Vitamin E, it is more readily absorbed. Since the supplement is fat soluble, this aids in delivery to the cells of the body.

Vitamin E is an essential nutrient because the body cannot produce it on its own. If you are not ingesting the proper amounts of it in your daily diet, you need to take a supplement. It is important to remember that improper preparation, cooking and storage can result in the loss of Vitamin E from the food.

Vitamin E is actually a combination of antioxidants, tocopherols and tocotrienols. Unfortunately, only alpha-tocopherol is actively maintained in the body. Therefore a supplement is needed to be sure the body is getting enough of the other ingredients that make up the complete Vitamin E.

Why do we need Vitamin E?

Part of its job is to protect Vitamin A and essential fatty acids from oxidation. When oxidation occurs in the cells, it breaks down body tissues.

Vitamin E Benefits:

Vitamin E has been found to aid in the prevention of heart disease. The oxidation of LDL cholesterol causes blockages in the coronary arteries. This often leads to atherosclerosis and heart attack. Vitamin E helps to prevent or at least delay these effects by limiting this oxidation. This has reduced the mortality rate due to coronary disease.

In its complete form, Vitamin E may be effective in reducing the risk of breast cancer in women who are genetically predisposed. It is being tested for its effectiveness in not only reducing the incidence of breast cancer, but also in inhibiting breast cancer cell growth.

Vitamin E is thought to protect the body against many forms of cancer due to its ability to increase immune system function. As an antioxidant, Vitamin E protects the body against the damaging effects of free radicals. These are believed to contribute to cancer cell production and the development of other chronic diseases. Vitamin E may also block formation of nitrosamines. These are carcinogens that form in the stomach from nitrites consumed through diet.

Another possible benefit to optimal amounts of Vitamin E in the diet is the prevention of cataracts. The clarity of the lens of the eye contributes to the formation of cataracts, blindness and eye disease. Vitamin E is being found to aid in the prevention of eye problems in people of all ages.

Vitamin E Warnings:

Vitamin E can produce harmful side effects if it is combined with certain medications. Consult your doctor before taking any dietary supplement to be sure it is safe for your use.

When taken as a supplement in its complete form, Vitamin E is nutritive and helpful in maintaining good health. Be sure when purchasing Vitamin E supplements that you are using Ester E for optimal benefits.

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Gently Narrow Your "Estrogen Window" With Lignan's
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Date: January 25, 2008 12:23 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Gently Narrow Your "Estrogen Window" With Lignan's

Although many people think that breast cancer is a genetically transferred disease, the truth is that it is rarely genetically transferred, as only one in every ten cases are linked to genes for this cancer. Strong evidence points to environmental causes being the main reason for breast cancer. By avoiding synthetic chemicals that mimic estrogens, a substantial fraction of these cancers can be prevented. These synthetic chemicals are called xenoestrogens. These xenoestrogens are manmade chemicals that either imitate or enhance the effects of estrogens in the body's cells and tell these cells to grow.

During puberty, this growth message is important to a woman's body and during pregnancy and the preparation for that. At this time period, estrogens are in full force, but if estrogen stimulation is increased by chemicals, cell growth is increased even more. Uncontrolled cell growth provides the foundation for cancer. As cells rapidly multiply, which is what happens when exposed to estrogens, the chance of DNA mutation is enhanced, which causes the creation of cancerous cells. A lot of women today also deal with increased estrogen stimulation over their lifetimes due to an early onset of menstruation, late menopause, and less time spent breastfeeding. The use of estrogen-containing oral contraceptives and post-menopausal hormone replacement also add to the estrogen burden, along with obesity and being overweight.

Estrogens affect cells by binding to receptor sites. However, there are tools that help to reduce the impact of areas that have a lot of receptor sites, such as the breasts. One of the main tools is lignans, which are a group or naturally occurring plant chemicals that are found in flaxseeds. Interest in lignans began with observational studies, which found a link between high intake and reduced risk of breast and colon cancers. Studies have reinforced those results, finding that lignans inhibit the growth of breast and colon cancer and also reduce the spread of skin cancer. The real benefit of lignans starts when they reach your intestines, where friendly bacteria convert them into phytoestrogens.

Phytoestrogens are a gentler estrogen, which bind to the same receptors that other estrogens bind, but don't have the growth-accelerating effects. While they are occupying these receptors, the less kind and gentle estrogens are unable to bind to them, resulting in both an estrogenic and estrogen-blocking effect. This explains why lignans are effective both for fighting against breast cancer and reducing the effect of hot flashes other symptoms during menopause. When estrogens are low, lignans act as weak estrogens, but when they are high, lignans act as estrogen blockers.

The risk for breast cancer is strongly affected by a woman's "estrogen window", or overall estrogen exposure that has been experienced over her reproductive years. The early onset of menstruation, no pregnancies, being pregnant after age 30, limited or no breastfeeding, short menstrual cycles, and late menopause all expand the estrogen window, increasing lifetime estrogen exposure along with the risk for breast cancer. By adding lignans to the diet, women can reduce the size of the estrogen window, and therefore, block the excess estrogen stimulation in estrogen-sensitive tissues like the breasts. Additionally, lignans are also believed to reduce the risk of colon and prostate cancers. When they are delivered along with omega-3-rich flaxseed oil, they promote better cholesterol balance, heart health, joint health, better bone density, greater endurance, better blood sugar balance, and healthy skin, hair, and nails.



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Vitanet®, LLC

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Revita
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Date: March 08, 2007 12:27 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Revita

Revita, the most efficient hair growth stimulating shampoo available in the market is the final result of DS Laboratories efforts on cutting edge research. Revita is a powerful and unique SLS/SLES free combination of active ingredients specially designed to maintain scalp vitality and act on folicle dysfunctions in order to achieve best results in short periods of time. Sodium Lauryl Sulfate and Sodium Laureth Sulfate, commonly used low cost detergents in shampoos and cleansers, are linked to skin irritation, skin drying and hair loss due to follicle attack. Revita is Sodium Lauryl Sulfate and Sodium Laureth Sulfate free, providing a high quality scalp skin safe shampoo product.

Revita was developed with a cost-no-object approach. Revita’s compounds have been chosen based exclusively on their properties, quality and efficacy (in the opposite of the majority of available products, which are usually developed with production costs in mind). The final result is a very high quality shampoo product with absolutely no equivalent competitor in the market. Revita combines costly first line compounds at high concentrations like Caffeine at 4.0%, Pyrus Malus (Apple) Seed Extract at 1.0% and Spin Traps (SOD Mimic) at 0.1% with other top level ingredients which make Revita a unique product in its class.

To improve the efficacy of this synergic combination, DS Laboratories developed a unique “chemical free” extraction process that keeps original properties and clinical efficacy of final components. Through gentle mechanical compression, Revita’s compounds are obtained as pure and chemically preserved active molecules.

Revita starts acting on your scalp and hair follicle since the first day of use. The time you will need to note the first results will depend of the severity and duration of your hair loss. No matter how long or how intense your hair loss is, using Revita on daily basis will improve the vitality of your scalp, maintaining the quality of your hair and stimulating new hair growth.

Through the synergic interaction of very effective compounds, Revita brings you a highly effective product designed to maintain scalp vitality and act on hair loss. By combining an antioxidant effect, anti-DHT properties, powerful hydrating molecules, hair growth stimulants and structural amino acids, Revita brings you the most effective hair growth stimulating shampoo available.

Apple Polyphenol (procyanidin B2 and C1) - phytochemical concentrate found in the skin of unripe apples that acts as potent antioxidant. It protects cells against free radicals, reactive atoms that contribute to tissue damage in the body. These chemical compounds are being studied extensively in labs around the world for their health effects in major diseases including treatment of hair growth. Studies showed that after sequential use, an increase of almost 80% of hair diameter and an increase in number of total hairs was shown, with no side effects.

In 2000, Japanese researchers presented their findings to the international community on the hair growth effects of apple polyphenols - specifically one known as procyanidin B-2. They identified two successful compounds- one from chardonnay grapes, and one extracted from unripe apples. The procyanidin B-2 fraction clearly outperformed the grape extract. "Procyanidin B-2 purified from apples," stated the research team, "shows the highest activity of more than 300% relative to controls."

In the same year, in a double-blind placebo-controlled trial, nineteen men with male pattern baldness were studied with a daily topical application of a 1% procyanidin B-2 solution, extracted from apples. Ten other balding men served as controls, receiving a placebo solution. After 6 months, the study concluded:

• The increase in number of total hairs and terminal hairs in the procyanidin B-2 group subjects was significantly greater than controls.

• 78.9% of subjects showed an increased mean value of hair diameter.

• "Procyanidin B-2 therapy shows promise as a cure for male pattern baldness."

Following the revelations, an attempt was made to further understand the mechanism by which the remarkable hair growth effects occurred. The results were published in the prestigious British Journal of Dermatology: Procyanidin B-2, extracted from apples, promotes hair growth: a laboratory study, Br J Dermatol. 2002 Jan;146(1):41-51. In this study, the researchers concluded that procyanidin B-2 acts to diminish protein kinase C isozymes, which play an important role in the hair growth cycle. Procyanidin B-2 seems to promote hair growth by down regulating PKC in both the anagen (active growth phase) and telogen (resting phase) of the hair follicle. When the anagen phase is prolonged, and the telogen phase is shortened, increased hair growth results.

Two more clinical trials and a total of seven published studies have now confirmed the surprising hair growth-promoting effects of apple procyanidins. Here is a summary of those findings:

• Total Number of Hairs: Significantly Increased

• Total Number of Terminal Hairs: Significantly Greater

• Increase in Hair Diameter: 78.9% Positive • Ratio of Thicker (terminal) Hairs: Significantly Higher

• Hair Follicle Activation: Intensive

In the most exciting development yet, Japanese researchers released a new study late in 2005. Once again, procyanidin therapy was proven successful in regrowing hair in subjects with male pattern baldness. The new study, published in the Journal of Cosmetic Dermatology, confirmed the findings of earlier studies, showing clear improvement in the number of hairs and the density of hairs in the treated area. Building on the success of earlier trials, the study was extended to 12 months in the procyanidin group, and proved that longer term procyanidin therapy was even more successful than prior 4 and 6 month trials.

Cooper Peptides - Cooper Peptides have two main properties: (1) potent tissue protective anti-inflammatory agents that limit oxidative damage after tissue injury, and (2) tissue remodeling activation agents, that is, the processes for removal of damaged protein and scar tissue and their replacement by normal tissue. Studies at numerous universities and research institutes have found copper-peptides to improve hair transplant success, increase hair follicle size, stimulate hair growth and reduce hair loss.

Research scientists at the University of San Francisco Wound Center stumbled upon very interesting results. Their discovery was made while applying a synthetically formulated compound, Copper Peptide, to severe wound areas on several patients. During this process something unusual happened. Not only did the wounds heal about 30 percent faster, but a significant stimulation of the follicular cells occurred. As a side effect, these tripeptide complexes actually grew hair around the wound area.

The discovery was so startling that they then applied the same Copper Peptide complex to a female patient who had suffered roughly 90 percent alopecia (hair loss) for years. After about six months of use, she had recovered almost 100 percent of her hair. Dr. Loren Pickart, the leading authority in Copper Peptide technology, describes it as being like a protein injection to the scalp.

Tests were then conducted with chemotherapy patients and recent hair transplant recipients, all with great success in stimulating newer and stronger hair follicles.

Spin traps – are very special compounds that were originally utilized in measuring free radical activity because they react with free radicals both in vitro and in vivo, producing stable complexes. The most commonly used spin trap and the standard which measures new ones is PBN - alpha-phenyl- N-tert butyl nitrone. Hundreds of studies have been conducted over the last ten years that have tested PBN and other “spin traps” in numerous conditions. Later it was discovered that these spin traps had powerful free radical quenching abilities in living systems and could treat a variety of conditions. Spin traps could provide unique protection against free radical damage that complements and enhances the activities of the classical antioxidants such as vitamin C and vitamin E.

Spin traps modulate NF kappa-B regulated cytokines and inducible nitric oxide synthases that are implicated in pro-inflammatory disease conditions. A method for ameliorating a cellular dysfunction of a tissue such as the treatment of hair loss and stimulation of hair growth comprises administering a nitroso or nitrone spin trap to the affected tissue. These agents inhibit the reaction of superoxide and nitric oxide to produce peroxinitrite. Scientists discovered that nitrone and nitroso spin traps have properties in the body for ameliorating cellular dysfunction in tissue attributed, in part, to high energy oxygen and hydroxyl free radicals, and enhancing recuperation of the tissue. Alpha-phenyl-N-tert butyl nitrone (PBN) can be administered, for example, as an anti-alopecia agent to stimulate hair growth.

Spin traps can be administered to the skin to be treated, such as the scalp. Depending on the type of hair loss or alopecia being treated and the conditions thereof, the stimulation of hair growth can usually be obtained by topical application, preferably repeated daily application. The utility of topically applied spin traps is not limited thereto, however, and the stimulation of hair growth can include an increased rate of growth, increased hair diameter, follicular neogenesis, and the like; inhibiting hair loss or alopecia from progressing.

Ketoconazole - Topical ketoconazole shows itself to have an anti-DHT binding effect in the scalp. Nevertheless, it is likely that ketoconazole exhibits other methods to its anti-hair-loss effect. One such theory of ketoconazole anti-alopecia effects may be on its activity upon the removal of sebum, a fatty substance that accumulates in the scalp around the hair follicles. In addition, ketoconazole is an antifungal medication and is significant for people combating hair loss since acting as an antifungal agent it reduces scalp irritation caused by fungal colonization or infection. Reduction of the inflammatory process that occurs in male pattern alopecia is crucial.

If we first examine the role of androgens, specifically dihydrotestosterone (DHT), we find that this hormone has been thought to slowly "choke" the growth of the hair follicle by inhibiting the function of an enzyme in the hair follicle called adenylate cyclase. Suffice it to say that when DHT concentrations remain high in the scalp, we see terminal (thick, coarse) scalp hair become reduced to vellus hair (fine, thin peach fuzz). On March 04, 2001, at the American Academy of Dermatology Meeting in Washington DC, scientists presented the findings of a study done on 1% ketoconazole shampoo which had good news for hair loss sufferers. In the study presented, one hundred male volunteers with mild to moderate dandruff and somewhat oily scalp, were using in a double-blind fashion either a 1% ketoconazole shampoo or a 1% zinc pyrithione shampoo, 2-3 times a week for 6 months.

Analysis of the different parameters set up in the study shows that the hair diameter gradually increased with ketoconazole use (+8.46%) over a 6 month period, whereas the diameter showed a trend to decrease with zinc pyrithione use over the same period (-2.28%). The sebum excretion rate was reduced with ketoconazole (-6.54%) while it increased with zinc pyrithione (+8.2%) over the same period of time. The number of hairs shed over a 24-hour period was reduced by 16.46% with ketoconazole and 6.02% with zinc pyrithione after 6 months. Finally, the percentage of hairs in the anagen phase increased by 6.4% and 8.4% respectively during the study.

The results are similar to a previous study done on 2% prescription strength Ketokonazole where it was shown that use of 2% ketoconazol yielded an increase in hair shaft diameter similar to what was achieved by the control group using 2% Minoxidil and a non-medicated shampoo.

Rooibos - Rooibos or Red Bush Tea - a hardy shrub indigenous to the North Western Cape of South Africa – is an exciting new botanical ingredient with potent antioxidant and anti-inflammatory properties well documented in medical literature. In alternative medicine Rooibos is often prescribed for nervous tension, allergies, stomach and digestive problems. Results from an independent study also showed a significant improvement in hair loss. Studies were initiated at an independent laboratory (Dermascan, France) to study the effect of the use of Rooibos in a hair lotion on a group of healthy persons who were suffering from the problem of hair loss. A 90 day trial was conducted comparing a hair lotion containing Rooibos with a placebo lotion.

After 90 days results showed a significant increase of the hair growth in the lotion containing Rooibos compared with the placebo. An increase in the hair growth was observed with 89% of the volunteers with no undesirable reactions (irritation or allergy). The participants were next asked to fill in a questionnaire. When the results were tallied, 67 percent rated their hair loss as zero or low, 78 percent saw a low to medium improvement, 45 percent saw a low to medium regrowth of hair, and 63 percent considered their hair had become smoother and shinier.

Conclusion: results show that most of the volunteers had a remarkable improvement in both the increase of hair growth and the decrease in hair loss.

MSM - Sulphur is present in protein-rich foods containing high levels of the amino acids methionine and cysteine. These foods include meat, fish, legumes, nuts, eggs, and vegetables, especially onions. However, sulphur has recently become a popular nutritional supplement and topical treatment thanks to the discovery of methylsulfonylmethane, or MSM.

The use of MSM as a nutritional supplement and topical application is relatively recent. An American chemist named Robert Herschler, began studying MSM in 1955. However, another man, Dr. Stanley Jacob with Oregon Health Sciences University in Portland, is considered by many to be the father of MSM. Dr. Jacob found that simple marine life like algae and plankton convert inorganic sulphur to organic sulphur compounds. These compounds are known as dimethylsulfonium salts. These salts are transformed into dimethyl sulfide (DMS), which is released into the atmosphere and is converted by ultraviolet light into dimethyl sulfoxide (DMSO). When DMSO oxidizes, it turns into MSM and is absorbed by plants that become food for animals and humans. MSM is a white, crystalline powder that is odorless and nearly tasteless. When taken as a dietary supplement, MSM proved to have the same health benefits as DMSO without side-effects such as bad breath, itchy skin, nasal congestion, and shortness of breath. Why does MSM help with the development of stronger hair? Various scientific studies have proven that MSM contributes a definite normalizing effect on body functions. The sulfur normally provided to the body by MSM is required for healthy collagen and keratin which are essential for healthy hair, skin and nails. MSM also has proven antioxidant benefits which can disrupt or alter damaging chain reactions of lipid peroxidation in the cell membranes.

MSM has been widely used as a dietary supplement without any reports of allergy or intolerance related to its use. Supplements of MSM are comfortably assimilated without side effects. There are no known contraindications.

Caffeine 4% - Active caffeine ingredient helps to regulate the effects of testosterone levels. Male pattern baldness is known to occur in individuals with sensitivity to testosterone, causing damage to hair follicles that eventually leads to baldness. Caffeine is a xanthine alkaloid compound that acts as a stimulant in humans. Caffeine is a central nervous system (CNS) stimulant, having the effect of warding off drowsiness and restoring alertness.

The independent study at the University of Jena used hair samples from the scalps of young men entering into the first stages of hormone-related hair loss. The study relied on a hair organ culture that used four different types of testing samples. The first was a nutrient-based sample, the second a testosterone only sample, the third was a caffeine only sample and the fourth a mixture of caffeine and testosterone.

According to the research, the results showed that the samples containing the caffeine nutrient helped to stave off hair loss and encouraged new hair growth, while the sample that relied on testosterone only led to increased hair loss. But perhaps the most impressive was the testosterone and caffeine sample, which helped to prevent further hair loss.

The results showed that using the caffeine treatment average growth was increased by around 46 per cent and the life cycle of the hair was extended by 37 per cent, when compared to the control study.

Carnitine Tartrate - L-Carnitine, a vitamin-like nutrient, occurs naturally in the human body and is essential for turning fat into energy. Active energy metabolism is an essential prerequisite for the growth of strong and healthy hair. In biological systems ATP acts as the universal energy currency. One of the most potent bio-actives that significantly increases cellular ATP content is carnitine tartrate.

Statistical evaluation demonstrated a significant increase in ATP equivalents in human hair roots treated with carnitine tartrate, showing that carnitine tartrate is an ideal ingredient for hair care formulations, providing energy for the optimal environment to produce strong and healthy hair. Throughout the test period ATP content within plucked hair follicles was determined twice daily using a commercially available test kit. Statistical evaluation of baseline adjusted values demonstrated a significant increase in ATP equivalents in human hair roots treated with carnitine tartrate. These effects were absent in the placebo group, thus underlining the stimulating activity of carnitine tartrate.

The outstanding bio-activity of carnitine tartrate was furthermore demonstrated in a second study, assessing the effects after a single application of a shampoo formulation supplemented with carnitine tartrate. Again, ATP levels in plucked human hair follicles were significantly increased.

Amino Acids: Ornitine, Taurine, Cysteine - Amino acids are the building blocks of protein, from which hair is created. They are assembled in the correct sequence by stem cells to form keratin, a complex and immensely strong hair protein. Vital amino acids have to be replaced consistently, as damage is accumulated over time. We can replace a combination of these lost amino acids directly into the hair, where they are shown to provide significant tensile benefits to the hair shaft.

Hair is composed primarily of proteins (88%). These proteins are of a hard fibrous type known as keratin. Keratin protein is comprised of what we call "polypeptide chains.” The word, polypeptide, comes from the Greek word "poly" meaning many and "peptos" meaning digested or broken down. In essence, if we break down protein, we have individual amino acids.

Many (poly) amino acids joined together form a "polypeptide chain". Two amino acids are joined together by a "peptide bond", and the correct number of amino acids placed in their correct order will form a specific protein; i.e. keratin, insulin, collagen and so on. The "alpha helix" is the descriptive term given to the polypeptide chain that forms the keratin protein found in human hair. Its structure is a coiled coil. The amino acids link together to form the coil and there are approximately 3.6 amino acids per turn of the helix (coil). Each amino acid is connected together by a "peptide bond". The peptide bond is located between the carbon atom of one amino acid extending to bond with the nitrogen atom of the next amino acid. In many individuals the extremities, including the top of the head, are the most difficult places to maintain blood flow. Follicles which are constantly deprived of blood, and therefore nutrients, cannot produce hair properly. Lack of proper nutrients, amino acids, minerals and vitamins can certainly hamper hair growth.

L-Arginine is a semi-essential amino acid synthesized by the body from L-Ornithine. Arginine + Ornithine support protein synthesis because they are involved in the transport and storage of nitrogen. The usage of taurine corrects the "rigidification" of the connective sheath that surrounds the Pilosebaceous unit and hair follicles, specifically those affected by pattern hair loss. This is a novel and previously undisclosed angle on hair loss treatment that has yet to be touched upon in any of the medical literature or prior publications.

The amino acid, l-cysteine speeds up hair growth and increases hair shaft diameter resulting in fuller hair. L-cysteine has been reported to facilitate longer hair growth, beyond what is genetically programmed. L-cysteine also provides potent antioxidant protection to the hair follicle. Users of topical n-acetyl-cysteine have reported hair regrowth.

Emu Oil - The emu, dromaius nova hollandiae, is a flightless bird part of a group called ratites which also includes the ostrich and the kiwi. Modern Australians learned early on from the Aborigines the many valuable qualities in the emu and its oil. The earliest research studies in emu oil come from Australia, and Australia continues to export emu oil to this day.

In the United States today there is a growing network of research labs interested in emus and their incredible oil. Emu oil is rendered from a thick pad of fat on the back of the bird that was apparently provided by nature to protect the animal from the extreme temperatures in its Australian homeland. Emu oil is deep penetrating and super hydrating to the skin - an all-natural tissue nutrient. Michael Hollick, MD, Ph.D., Professor of Medicine, Physiology, and Dermatology at Boston University School of Medicine conducted a study involving emu oil and hair growth. His study found that there was a 20% increase in growth activity of skin that received emu oil compared to skin that received corn oil. Looking at the hair follicles Dr. Hollick realized they were much more robust, the skin thickness was remarkably increased suggesting that emu oil stimulated skin growth and hair growth. Additionally, the study showed that over 80% of hair follicles that had been "asleep" were woken up, and began growing.

Emu oil is anti-inflammatory, which may be in part why it stimulates hair growth. Emu Oil has also been shown to be a 5 alpha reductase inhibitor in target tissues when topically applied, which likely contributes significantly to its hair growth properties. A third important property of emu oil is that it is bacteriostatic.

Emu Oil contains a multitude of Essential Fatty Acids (EFA) which helps to "feed" the skin. Consumers who suffer from natural forms of baldness have reported hair re-growth. Since Alopecia Areata only suppresses the hair follicle (vs. killing the hair follicle), emu oil may have an effect to assist with hair regrowth.

Biotin – Biotin is a member of the B-vitamin family and a major component in the natural hair manufacturing process -- it is essential to not only grow new hair, but it also plays a major role in the overall health of skin and nails. The beneficial effects of biotin on hair may be linked to its ability to improve the metabolism of scalp oils. Biotin when absorbed by the scalp may promote hair growth and it is able to penetrate the hair shaft making it expand which actually thickens the hair cuticle.

Biotin is used in cell growth, the production of fatty acids, metabolism of fats and amino acids. It plays a role in the Krebs Cycle, which is the process in which energy is released from food. Biotin is so important to hair health, that many dermatologists prescribe biotin supplements to their patients as part of their medical treatment for hair loss.

After applying Revita with a gentle massage, you should leave it on the scalp from 1 – 2 minutes before rinsing. Then repeat and leave on the scalp for 3 – 5 minutes. If desired, follow with a high quality conditioner. For optimal results, Revita should be used at least 5 times per week.

This formulation is contraindicated in individuals with a history of sensitivity reactions to any of its components. It should be discontinued if hypersensitivity to any of its ingredients is noted.

Q. Is Revita safe ?

A. Revita primarily contains compounds that are not only safe in topical use, but actually dramatically enhance overall skin health. The other active ingredients such as Ketoconazole have been tested in clinical studies and have been shown safe.

Q: Can I use hair sprays, mousses, gels, etc.?

A: Hair spray, gel, and other styling aids are not recommended since they tend to clog the hair shaft. However, you can use them while using Revita.

Q: Can I have my hair colored or permed while using Revita ?

A: While there is no evidence that coloring or perming hair can lead to or even worsen hair loss, it is generally not recommended for people with hair loss. If you are experiencing hair loss then perming and coloring hair is not recommended. However, this will not interfere with Revita.

Q: What is SLS/SLES free ?

A: SLS means Sodium Lauryl Sulfate and SLES means Sodium Laureth Sulfate, commonly used low cost detergents in shampoos and cleansers. They are linked to skin irritation, skin drying and hair loss due to follicle attack. Revita is Sodium Lauryl Sulfate and Sodium Laureth Sulfate free, and that means that Revita does not irritate you scalp and preserves your hair follicale health.

Q: Can I blow dry my hair after using Revita ?

A: Extreme heat damages the proteins in the hairs making them fragile. Nevertheless, if you need or want to blow dry your hair, you can do it after using Revita.

Q: Who is a candidate for Revita ?

A: Ideal candidate is someone with little hair loss or at the beginning stages of hair loss, since it is much easier to prevent hair loss then to grow new hair. Someone who is concerned with hair loss prevention should start using Revita immediately.

Q: What type of results should I expect with Revita ?

A: When deciding to use Revita, it is important to have realistic expectations. Depending of severity and duration of your hair loss, it could take some time to see hair growth. In fact, during the first 2 weeks of treatment you may actually notice increased hair loss as old hairs are being pushed out and the hair follicles start growing new hair. Do not become alarmed with this and just stick to the treatment.

Q. Does Revita have any systemic side effects ?

A. No, when used as directed, Revita active ingredients have a long history of use both orally and topically.

Q. Does Revita work for women?

A. Yes. In most cases, the cause of hair loss in women is surprisingly similar to men. Fortunately for women, estrogen helps to protect the hair follicle from the destructive effects of DHT. However, many women develop thinning hair and loss due to fluctuation of estrogen levels and/or over production of DHT. Revita can help protect the hair follicle from DHT resulting in a thicker, fuller and healthier hair.

Q. I am using other topical treatments. Can I use Revita at the same time ?

A. Yes. Revita has no side effects and does not cross react with other topical treatments. You can safely opt to use Revita with other products, and we strongly recommend the association with Spectral.DNC for more severe hair loss or Spectral.RS for thinning hair.

Q. Do I need to use Revita for a long time ?

A. Once you have reached the desired results, you should continue to use Revita as your regular shampoo to maintain the revitalized hairs and a healthy scalp.

Q: Is stress a factor in hair loss?

A: When the body is under significant physical and emotional stress it is possible that the immune system will produce anti-bodies that attack hair follicles, and this results in bald patches or diffuse loss. Stress-induced loss will respond very well to Revita and you should keep using Revita as your regular daily shampoo to keep your scalp healthy.

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Dr. Nugent’s Genetic Key Diet Notes Why is America Losing the Fat Battle?
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Date: September 19, 2006 05:48 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Dr. Nugent’s Genetic Key Diet Notes Why is America Losing the Fat Battle?

MSG Factor: increases appetite, triggers something in your body that makes you want more. There are no genetically fat rats but they make them fat by giving them MSG. they have taken an animal that has no natural obese traits or genetics and “enhanced” them. MSG is a flavoring that makes you want to eat more. The phrase “Betch ya cant eat just one!” has true meaning! It is in highly processed foods under different labeling names so that we purposely don’t see the words MSG (Monosodium Glutamate.)

Most tenderizers are high in MSG, “accent” and “adolph’s” are among the list. your fast food restaurants’ are guilty as well. It’s what keeps you coming back and eating far more than you should need.

“Packages that say no MSG is because they are now putting tow preservatives that combine together to make MSG. Ascorbic Acid (preservative), and benzene salts combine to make MSG when heated. Soft drinks are stored in hot ware0houses, transported in hot trucks, and cans heat to over 100 degrees. Soft drinks do not have MSG added, but end up with it.”

Ascorbic acid and benzoate salt are preservatives that are combined in soft drinks and boxed fruit juices. When the drinks are exposed to heat and light the combination can stimulate the formation of benzene. We all know from reading Dr. Nugent’s Toxic Planet book that benzene is highly toxic in levels far below what the EPA states as safe. Considering that a lot of people live in warm, even hot states, the distribution centers and trucks are not kept cool, these drinks are heated in transport and storage. The soft drinks can end up with low levels of benzene. Your body doesn’t have the need, desire or tolerance for benzene at any level! If there ever was a good reason to get off soda and boxed drinks! Think about it.

Have you ever eaten to much at a nice restaurant, maybe a buffet and you must clean up your plate. The next day, you’re starving! Could be the MSG hangover.

Our brain needs 10 teaspoons of glucose each day for normal function. Because people have been warned about the problems with sugar we have added the pink, yellow & blue packets. Worse.

I stood in line behind a woman buying a small sack of prescriptions with a big price tag. She said its very expensive to be sick. (And she had a bottle of diet soda to go along with it.)

My husband said one time, “well, sooner or later we’re all going to get something and die.” I answered – “No-o-o, sooner or later we’re all going to die, but we don’t have to get sick.”

I used to subscribe to prevention magazine. After seeing so many advertisements for drugs, I dropped it. What is there in prevention that could cause me to take a drug?

Try Glyconutrients instead.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1391)


How to deal with Stress and Cortisol...
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Date: August 30, 2006 09:36 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How to deal with Stress and Cortisol...

Beating the Aging Odds

All of us grow older, but aging is a choice. You have it in your power to retain much of the health, vitality and beauty of your youth. It boils down to a simple fact – retard oxidative stress and you’ll retard the aging process. The 70 million people who make up the “boomer” generation and are getting ready for an active retirement welcome this news.

Stress and Cortisol

The early twentieth century “stress doctor” Hans Selye, M.D. was renowned for his work on the human adaptive response and the effects of stress on aging. He taught that every stress leanves an indelible scar, and the organism pays for its survival after a stressful situation by becoming a little older. That’s because stress raises levels of the adrenal hormone cortisol. It increases internal generation of free radicals, disrupts normal metabolism and leads to aging conditions. Because of this, cortisol has been dubbed the age-accelerating hormone.

The more stressful our lifestyle and the level of environmental hazards we are exposed to, the higher cortisol levels will climb in an effort to jump-start our adaptive response. Coupled with a poor diet, this is a recipe for pre-mature aging. At least eleven major aging factors are related to high cortisol levels:

  • Breakdown of collagen and elastin in muscles, joints, and bone
  • Memory loss and reduced cognitive function
  • Increased cardiovascular risk
  • Hypertension and fluid retention
  • Disordered lipid metabolism (total cholesterol, triglycerides, HDL to LDL ratio)
  • Decreased immune function
  • Increased inflammation (vascular network, allergies, asthma, acne and hair loss)
  • Hormone imbalances
  • Disordered sugar metabolism
  • Skin problems (wrinkling, psoriasis, seborrhea, acne and hair loss)
  • Nerve system damage

So, there you have it. Now let’s see how to tame cortisol and reduce oxidative stress.

Reducing Cortisol and Oxidative Stress

Be in the moment – stress reducing techniques such as meditation, prayer, visualization, yoga, chi gong, and listening to inspirational tapes induce calmness and a sense of balance.

Eat right for your genes – as we get older, we don’t digest animal protein as efficiently as when younger. Shifting to plant source proteins that are easier to digest and contain the full complement of vitamins and minerals is most desirable. We are accustomed to thinking of dairy, meat, poultry, and fish as “protein.” All vegetables are good sources of protein. Along with legumes, whole grains, and nuts, daily protein needs are easily fulfilled. Meals that combine a variety of tastes from plant foods also require less salt for flavor enhancement and this helps keep hypertension at bay. So, explore just how good meals can be that either do not contain meat or use it as a condiment. If you do need some salt, try substituting table salt with NOW Vitamins Potassium Chloride crystals.

Enzymes Increase Digestion

Use digestive enzymes such as Optimal Digestive System to insure that you are absorbing all the nutrients in your food. This product has been clinically tested for its digestive effectiveness helping to digest fats, carbs, proteins and even gas producing beans and cruciferous vegetables. Other enzymes, Serrazimes is a systemic enzyme that will help keep lymphatic’s clear of debris, support immune function, and boost your adaptive response to stress.

Tame Cortisol

As many people reach middle age they have a tendency to gain weight around the navel. High stress amps up levels of cortisol that results in increased girth. Middle body fat is considered a significant risk factor for impaired glucose metabolism and cardiovascular disease. Check your waist to hip ratio by dividing your waist measurement in inches by your hip measurement. If you have a ratio of 0.85 or below, you have lower risk of insulin resistance and cardiovascular disease. This measurement is one of the best indicators of cortisol induced metabolic syndrome and weight gain.

Super cortisol support with Relora is an herbal, vitamin and mineral formula that’s designed to fight mid-body fat by taming cortisol. Its key ingredient is Relora which is a blend of the herbal extract of Phellodendron amurense and Magnolia officinalis. A small double blind clinical trial found that pre-menopausal obese women – half of whom took Relora – lost a significant amount of weight. These were women who eat in response to stress. Thus the researchers proposed that Relora appeared to reduce cortisol and perceived stress, resulting in weight loss. Super cortisol support also contains Ashwagandha and Rhodiola, herbs traditionally use for increasing adaptive response and reducing stress. You can read about these herbs and other nutritional products in the book 7-syndrome healing: supplement essentials for mind and body. Written by myself and coauthor Jayson Kroner. This book can be ordered from Now Foods.

Additionally, Chinese scientists found that the active components in Relora called honokiol and magnolol delayed gastric emptying, which would make you feel full longer. An additional anti-aging benefit was observed by another group of Chinese scientists. They reported that honokiol is a potent arterial thrombosis inhibitor because it inhibits prostacyclin release; a promoter of platelet adhesion. Platelet stickiness increases stroke risk. Phellodendron and Magnolia have been used in Chinese medicine for centuries.

Quell Free Radicals

Health and longevity essentially rests on the body balance between free radical load and antioxidant reserves. Toxic exposure depletes some of your antioxidant reserves. Eating a diet rich in antioxidant fruits, vegetables, legumes and grains, helps you rebound. Continued toxic exposure will challenge your antioxidant status and may overwhelm your reserves. VitaBerry Plus+ is a powerful antioxidant formula that contains a range of high ORAC fruits that naturally augment the diet. ORAC stands for oxygen radical absorbance capacity. It is a measure of the ability of a food to quell oxygen free radicals, the most dangerous kind. VitaBerry Plus+ is a product after my own heart. In my book The Anti-Aging Solution, I wrote about how different color foods protect DNA and prevent aging. VitaBerry Plus+ contains the important colors described in my bood. You can order your copy from Now Vitamins.

True-E Bio Complex rounds out the antioxidant colors. It contains all eight tocopherols and eight tocotrienols in the natural ratio found in “tan” foods such as whole grains and legumes. It is the only natural vitamin E that is produced from soy that has not been genetically modified.

The best anti-aging advice I can pass on is from my friend and food columnist Joan Jackson. “Take Pleasure in Your Life TODAY and Enjoy What You Eat”



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Buy Now Vitamins, minerals and herbs at Vitanet

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Setting the Record Straight on Vitamin E
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Date: August 04, 2006 02:19 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Setting the Record Straight on Vitamin E

Vitamin E has become a staple nutrient in the lives of millions, and is considered by many to rank among the most vital antioxidant compounds ever developed as a dietary supplement for the health seeking public. Over the past eighty years the industry’s top scientists have made many discoveries on Vitamin E’s wide range of beneficial effects, via research conducted in some of the scientific community’s most advanced clinical settings.

As one of the Natural Product Industry’s leading suppliers of Vitamin E, Now Foods would like to share with you just a few of the measures we’ve taken to set the record straight on Vitamin E.

  • Now Vitamin E products are rooted in sound science, containing only 100% natural “d-“ forms. No synthetics (dl-) are used, and thorough testing is done to verify the absence of heavy metals, pesticides, microbes and other contaminants.
  • Each formula meets FCC and USP standards, making Now Foods Natural Vitamin E products both food grade, as well as pharmaceutical grade. This is the industry’s highest standard of purity and serves as one of the strongest pieces of evidence supporting the integrity of our Vitamin E products.
  • Now Foods Vitamin E is derived from vegetable oils, and safely processed in a manner that reduces the possibility of residual proteins and DNA. This virtually eliminates the potential for soy allergens or genetically modified genes. What remains, is a 100% natural-grade product, set in a safe oil base to positively enhance absorption.
  • Now Foods does not include additional soybean oils in our full-spectrum, 8-isomer Vitamin E formulas. Instead we rely on rice bran and olive oils. Our true-E bioComplex was scientifically formulated to deliver an optimally balanced isomer ratio of tocopherols and tocotrienols close to that found in nature in healthy ratios.
  • In just the past few years, our Natural Vitamin E formulas have been honored with multiple industry awards, including four consecutive 1st place Vity Awards for “Best Vitamin E.” their long history of success has made them a favorite among health conscious consumers, and a best seller among retailers.
  • Now Foods Nutrition Manager, Neil Levin, CCN, DANLA, has authored scientific papers reviewing the true science of Vitamin E, which are accessible on the website of peer reviews scientific journals, including the Annals of Internal Medicine, the British Medical Journal and CA: the Journal of American Cancer Society. As a well recognized expert in this field, Neil is the principal formulator of Now Foods Patented Tru-E BioComplex – the industry’s first identity preserved, non-GMO Vitamin E containing all eight natural isomers (distinct forms) as found in nature in healthy ratios.
  • Now Foods

    (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1341)


    The True Whey, boost your immune system
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    Date: April 29, 2006 02:09 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: The True Whey, boost your immune system

    The True Whey™


    Premium Protein Powder

    The True Whey is a superior source of complete, biologically active, immunity-boosting protein. It is easy to mix and tastes great, a powerful addition to your daily health regimen. The True Whey is a non-denatured whey protein concentrate, produced to maintain the fragile, immune-boosting, and regenerative components naturally present in fresh milk. Highly digestible, whey has one of the highest biological values of any protein source. Traditionally, whey is formed from the liquids that separate from the milk solids in the cheese-making process. Often, the process involves high temperatures and acidic conditions that may denature the nutrients. The True Whey, however, is made from a unique, proprietary process that preserves the nutrients of the whey. In each 10 grams, you receive 8 grams of protein, 900 mg immunoglobulins, 190 mg lactoferrin, 40 mg calcium, 60 mg potassium, and 30 mg phosphorus. The True Whey provides whole protein, not protein isolates. Intact, biologically-active proteins support your immune system, regulate the use of minerals in the body, protect the digestive tract, and protect your body from oxidative stress. The typical American diet is glutted with refined sugars, carbohydrates, and fats which can have a significant impact on your health. To balance these influences and support normal weight, energy levels and overall health, each 10 grams of The True Whey contains 80% protein and only 38 calories, 6% total fat, 3% saturated fat, and 8% carbohydrates. The True Whey is made from milk from contented cows, which are grass fed and never subjected to any growth hormone treatment, chemicals, pesticides, or genetically modified organisms (GMO's).

    Supplement Facts
    Serving Size: 10 g (1 rounded scoop)
    Serving per container 45

    Amount %DV
    Whey Protein Concentrate 10 g
    Protein 8 g 15
    Immunoglobulins* 900 mg
    Lactoferrin* 190 mg
    Calcium 40 mg 4
    Calories 38
    Calories from Fat 6
    Total Fat 0.5 g <2
    Saturated Fat 0 g <2
    Cholesterol 15 mg 4
    Sodium 20 mg 4
    Total Carbohydrate 1 g <2
    Dietary Fiber 0 g >2
    Sugar 1 g <2
    Potassium 60 mg
    Phosphorus 30 mg
    *Naturally occurring. Amounts may vary.

    Other Ingredients:

    Warning: If you are allergic to dairy products or are pregnant or breastfeeding, consult your health care professional before using this product. If you are taking prescription drugs, including antibiotics, consult your health care professional before using this product.

    Suggested Use: Blend one scoop (10 grams) into your favorite cold beverage. Add ice and blend with fruit or yogurt for a delicious smoothie.

    (https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1257)


    New Frontiers in Enzyme Supplementation
    TopPreviousNext

    Date: February 16, 2006 04:17 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: New Frontiers in Enzyme Supplementation

    New Frontiers in Enzyme Supplementation

    By Nick Rana, CN, NOW Quality Assurance

    Serrazimes® is a proteolytic (protein digesting) enzyme system containing protease that is derived from edible non-genetically engineered fungi (Aspergillus oryzae and Aspergillus melleus), that is designed as an alternative for Serrapeptidase (also known as serratio-peptidase and serrapeptase) in dietary supplements used for cardiovascular, anti-inflammatory, respiratory, or immune support.

    Serrapeptidase was initially isolated from Serratia marcescens, a potentially pathogenic bacteria found in the gut of the Japanese silkworm. Recognized as a pharmacological agent, Serrapeptidase has wide clinical use in Asia and Europe for the management of assorted inflammatory processes (Rothschild, 1991). In recent years, recognition of the efficacy of the Japanese product has lead to growing interest in the US dietary supplement market.

    The product’s efficacy and availability over the internet has fueled its popularity in the US dietary supplement industry, where it is used for anti-inflammatory support, cardiovascular support, respiratory support, and as an adjunct to antibiotic therapy. Recognizing the potential for a "Serrapeptidase-type” enzyme in the U.S. dietary supplement market, the National Enzyme Company developed a protease system that has the same in vitro (lab test) activity as Serrapeptidase, but that is from organisms that have a long history of safe use in dietary supplements. Serrazimes® is the product resulting from this search.

    Since the 1960’s, plant and microbial protease enzymes have been studied for their role in the management of inflammation and inflammatory processes. In both animal and human trials, proteolytic enzymes, from a variety of sources, have repeatedly been shown to significantly reduce inflammation resulting from sickness or injury (Ryan, 1967)(Smyth et al, 1967)(Shaw, 1969)(Kumakura et al, 1988)(Lomax, 1999). The earlier research on the anti-inflammatory actions of proteases pointed entirely to their antithrombic and fibrinolytic aspects to explain this phenomenon. However, studies by Parmely (Infect and Immun Sept 1990) and others indicate that, in addition to degrading fibrin, microbial proteases may actually inactivate pro-inflammatory cytokines and to interrupt inflammatory responses.

    Persons taking blood thinning or antibiotic medications and those with serious health disorders should consult their medical practitioner prior to taking Serrazimes®. As is the case with most supplements, please consult your doctor about the use of Serrazimes® during pregnancy and lactation.

    The Product Development Team at NOW Foods is constantly researching new products like Serrazimes® to provide our customers with the tools that empower them to live healthier lives. Look also for our new unique digestive enzyme formulations from plant sources - backed by laboratory studies - to be introduced in March of 2006.

    TECHNICAL NOTES:

    Serrapeptidase is a selective alkaline metalloprotease enzyme, meaning that it works to activate specific biological systems of mammals and directly degrades or inhibits IgG and IgA immune factors as well as the regulatory proteins á-2-macroglobulin, á-2-antiplasmin, and antithrombin III (Molla et al, 1989)(Maeda and Molla, 1989).

    While originally isolated from Serratia marcescens, a bacteria found in the gut of the Japanese silk worm, Serrapeptidase activity is also found in fermentation extracts of Serratia E-15, Aspergillus oryzae, and Aspergillus melleus. (Salamone and Wodzinski, 1997).

    The Serrapeptidase activity of this high potency proteolytic (protein digesting) enzyme is determined using a spectrophotometric assay testing procedure that measures the enzyme’s ability to hydrolyze (digest) a standard casein protein substrate. Laboratory analyses have established that Serrazimes® has a 1:1 enzymatic equivalent of Serrapeptidase activity guaranteed to provide 600,000 specialized proteolytic Units per gram, or 20,000 units per capsule.



    --
    Buy Serrapeptase at Vitanet ®

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    Omega man
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    Date: January 21, 2006 01:10 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Omega man

    Omega Man is the ideal essential fatty acid and plant phytochemical formula to support optimal health, life and vitality at any age. From the athletic pursuits of your early 20’s to the health concerns of your 50’s, 60’s, and beyond, Omega Man is your answer. Let Omega Man unlock the door to a new, more vibrant, healthier you.

    The Omega Man Formula

    Organic Flaxseed Oil
    Barlean’s award-winning organic flaxseed oil makes up the base of this formula providing the richest and freshest source of essential omega-3 fatty acid essential for overall health and vitality.

    Lignans
    Omega Man contains high-in-lignan flaxseed particulate. Numerous studies have reported on the role of lignans in support of heart and hormonal health including the preservation of healthy prostate tissue. Lignans once abundant in a whole foods, plant based diet are now sparse in our modern-day diet making supplementation so important.

    Styrian Pumpkin Seed Oil
    Barlean’s went to the edge of the earth to procure the seeds of a rare and unique pumpkin found only in the region of southeast Austria. It is reputed for its extraordinary and high levels of phytosterols, important super vitamins that have been shown to speed exercise recovery, soothe painful joints, and increase vitality. Phytosterols are also important in the support of heart and prostate health.

    Phospholipid Concentrates
    Phospholipids are an important component of every single cell in your body. Phospholipid supplementation has been shown to promote heart, digestive, liver, immune and brain health. Omega Man delivers the ideal dosage of phospholipids for your good health.

    Plant Phytosterol Complex
    Phytosterols are all natural plant chemicals derived primarily from seed oils. Omega Man contains three important types of phytosterols—Beta Sitosterol, Campesterol, and Stigmasterol. These powerhouses are important for the healthy support of the prostate, colon, and cardiovascular system. Phytosterols are also a favorite of high performance athletes.

    Ingredients
    Organic flaxseed oil, organic flaxseed particulate, styrian pumpkin seed oil, phospholipids concentrates, plant phytosterols, rosemary/ascorbic acid blend. Free of Genetically Modified Organisms.



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    Vitamin C FAQ's
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    Date: December 27, 2005 05:11 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Vitamin C FAQ's

    Vitamin C FAQ's

    What is Calcium Ascorbate?

    Calcium Ascorbate is a buffered salt (mineral) form of the water-soluble antioxidant Vitamin C (ascorbic acid). Calcium is reacted with ascorbic acid to buffer the acidic nature of this vitamin, making it more gentle for the special needs of those who may have a sensitive gastrointestinal tract. The pH of this buffered mineral Ascorbate is approximately 6.8—7.4 as compared to ascorbic acid that is about a pH of 2.5. Calcium Ascorbate provides approximately 10% elemental calcium.

    What does Calcium Ascorbate do?

    Ascorbate (vitamin C) is a reducing sugar (has a reactive ene-diol structure) that is involved in biochemical processes such as hydroxylation of proline and lysine utilized in the formation of collagen and healthy connective tissue. A deficiency in Ascorbate results in a disease called scurvy which manifests as weakened collagen fibers, rotting teeth, delayed healing and open sores on the skin. Ascorbate is involved in many other vital functions such as the mobilization of iron, stimulation of immune system and as an anti-oxidant for scavenging of reactive free radicals.

    Is this a necessary vitamin or can our bodies make enough to satisfy our needs?

    Many plants and animals do not need to consume foods high in ascorbic acid to meet their need for Vitamin C because they are genetically programmed to produce enzymes that convert glucose into ascorbic acid. Unfortunately humans have only 3 of the 4 enzymes necessary for internal production of ascorbic acid, therefore we must satisfy our physical needs for this important vitamin through our intake of foods rich in vitamin C and/or take a good supplement.

    What is the function of the Citrus Bioflavonoids?

    Bioflavonoids are biologically active Flavonoid compounds found throughout the entire plant kingdom. Since the discovery of Flavonoids in 1936 when they were first isolated from lemons and called citrin and Vitamin P over 4,000 different types have been characterized. Though there are several forms of Bioflavonoids in the complex the predominant form is Hesperidin. These Flavonoids exhibit beneficial effects on capillary permeability and therefore support blood flow. They are antioxidants that work synergistically with Vitamin C as well as exhibiting anti-inflammatory activity.

    Why are there color variations in your different Vitamin C products, and are they safe to take?

    Most natural Vitamin C products vary in color from batch to batch and bottle to bottle. There are normally variations in the color of the raw material used during manufacturing, which is a normal occurrence. This is due to natural color variations in the source of the Vitamin C – generally, you will find C supplements to range in color from a light tan color to a light gray color.

    Over the course of the shelf-life of a Vitamin C supplement, oxidation can cause a slight change in color, so you may find the light tan C-1000 you bought has changed to a darker tan six months later. This is a normal occurrence, and the product is safe to use up until the expiration date, and even beyond. NOW® is generally conservative with expiration dates, so a Vitamin C product is still safe after the date, it just may not be as effective due to oxidation.

    Why does your Ester-C Complex say 625mg on the front of the label but list 500mg on the Supplement Facts panel? The key word is “complex”. Ester-C Complex is a combination of ascorbic acid (natural Vitamin C) and Calcium Ascorbate, which ultimately yields 500 total mg of Vitamin C. It is complexed with Calcium Ascorbate and other metabolites for greater absorption and faster utilization by your body. So the total complex is 625mg of Ester-C Complex, which yields 500mg of natural Vitamin C as ascorbic acid.

    NOW Ester-C Pure Powder states the serving size is ½ teaspoon. How much Vitamin C am I getting with this serving size? ½ teaspoon of Ester-C Pure Powder is equivalent to 2000mg of natural Vitamin C and 250mg of Calcium.

    Can I pour the powder in NOW® Vitamin C capsules into a liquid instead of swallowing the capsule? Many people do not want to or cannot swallow capsules, tablets or softgels, for various reasons. Encapsulated Vitamin C products from NOW® can be opened and dumped into a liquid for consumption. Juice or water is recommended if you choose this method. However, taking Vitamin C with water on an empty stomach is the recommended method of ingestion. We do not recommend trying this method with Vitamin C in tablet form, although you can grind or smash a tablet into powder form and add to water or juice. If you choose to do this, use a mortar and pestle for best results and minimal loss of product. Why go through the trouble when NOW® carries Vitamin C in a powdered form already. Save yourself time and trouble by ordering this form instead. Disclaimer: This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

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    Nattokinase Fact Sheet
    TopPreviousNext

    Date: December 08, 2005 05:14 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Nattokinase Fact Sheet

    Nattokinase Fact Sheet

    Neil E. Levin, CCN, DANLA 8/8/05

    LIKELY USERS: People seeking to support heart health and healthy circulation.1-6

    KEY INGREDIENTS: Nattokinase, an enzyme

    STRUCTURE/FUNCTION USE: Nattokinase is an enzyme isolated from Natto, a traditional Japanese fermented soy food. Natto has been consumed safely for thousands of years for its numerous health benefits. More recently, both clinical and non-clinical studies have demonstrated that Nattokinase supports heart health and promotes healthy circulation. Each serving of NOWR Nattokinase provides 2,000 FU (Fibrinolytic Units) to help keep already healthy levels of blood clotting factors within a normal range. 1-6

    ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: An assay of 2,000 FU (Fibrinolytic Units) is equivalent to 160 IU on the Urokinase assay. The FU assay measures Nattokinase activity by using the fibrin plate method and measuring the absorption of released low-molecular weight substances.7 NOW Nattokinase is made from non-GE (non-genetically engineered) bacteria (Bacillus subtilis var. Natto) grown on non-GE soybeans and standardized on a base of non-GE, corn-derived maltodextrin.

    SERVING SIZE & HOW TO TAKE IT: Take one vegetarian Vcap once or twice a day between meals (without protein).

    COMPLEMENTARY PRODUCTS: Vein SupremeTM, Tru-E Bio ComplexTM, Pycnogenol®, garlic, and cayenne

    CAUTIONS: None.

    SPECIFIC: People with blood coagulation disorders or who take anticoagulant (“blood thinning”) medications (including aspirin) should consult a physician before use. Do not take if prone to bleeding. Unlike some other brands, NOWR Nattokinase contains no Vitamin K (K1 or K2), which would enhance clotting.

    GENERAL: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. Information given here may vary from what is shown on the product label because this represents my own professional experience and understanding of the science underlying the formula and ingredients. When taking any new formula, use common sense and cautiously increase to the full dose over time.

    Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

    REFERENCES:

    1. Fujita M, Hong K, Ito Y, Fujii R, Kariya K, Nishimuro S (1995) Thrombolytic effect of nattokinase on a chemically induced thrombosis model in rat. Biol Pharm Bull 18(10):1387-1391
    2. Sumi H, Hamada H, Nakanishi K, Hiratani H (1990) Enhancement of the fibrinolytic activity in plasma by oral administration of nattokinase. Acta Haematol 84(3):139-143.
    3. Suzuki Y, Kondo K, Ichise H, Tsukamoto Y, Urano T, Umemura K (2003) Dietary Supplementation With Fermented Soybeans Suppresses Intimal Thickening. Nutrition 19:261-264.
    4. Suzuki Y, Kondo K, Matsumoto Y, Zhao B-Q, Otsuguro K, Maeda T, Tsukamoto Y, Urano T, Umemura K (2003) Dietary supplementation of fermented soybean, natto, suppresses intimal thickening and modulates the lysis of mural thrombi after endothelial injury in rat femoral artery. Life Sci 73:1289-1298.
    5. Ito H, Suzuki T (2002) Effect of oral administration of nattokinase extract on blood mobility. Society of Analytical Bio-Sciences 25(4):1-5.
    6. An Open Clinical Pilot Study to Evaluate the Safety and Efficacy of Natural Super Kinase as an Add-On Oral Fibrinolytic Agent to Low Molecular Weight Heparin and Anti-Platelets in Acute Ischaemic Stroke. (no authors listed) (2004)
    7. Method: J of Agri Food Chem, Vol 48 (2000) P3, 210-213, 216



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    Tru-E Bio Complex
    TopPreviousNext

    Date: December 08, 2005 04:58 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Tru-E Bio Complex

    Tru-E Bio Complex TM

    Neil E. Levin, CCN, DANLA 7/27/05

    LIKELY USERS: Most Americans are deficient in Vitamin E 8,9,10; People needing superior antioxidant protection3,5,6; People needing cardiovascular or cholesterol support27,30,31; People needing nervous system support7; Those wanting healthier skin6; Diabetics may need additional Vitamin E24 KEY INGREDIENTS: Tocopherols from IP-Preserved, non-GMO Soy; Tocotrienols and tocopherols from non-GMO virgin palm; Tocotrienols from non-GMO annatto seed

    MAIN PRODUCT FEATURES: NOW Tru-E Bio ComplexTM is a unique biologically balanced, patent-pending formula designed to provide optimal Vitamin E activity. This product features 100% natural, Non-Genetically Modified sources of all 8 isomers (forms) of the Vitamin E “family” in ratios similar to what is found in a healthy diet. It provides the superior benefits of foodsource Vitamin E versus those obtained from traditional E supplements.

    NOW® Tru-E Bio ComplexTM has been carefully blended to supply high levels of the natural gamma and delta “desmethyl” forms of both tocopherols and tocotrienols. This is important because recent research indicates that these isomers work best as a team to quench the lipid and nitrogen free radicals known to cause injury to cells and tissues. This product supports a healthy cardiovascular system, youthful skin and nervous system function with potent antioxidants. This science-based natural Vitamin E supplement is unlike any other and the first to combine all of these benefits in one convenient non-GMO formula! 25-32

    Recent research indicates that these isomers work best as a team to quench the lipid and nitrogen free radicals known to cause injury to cells and tissues.1-4, 25-32

    This product supports a healthy cardiovascular system, youthful skin and nervous system function with potent antioxidants.1,4-7

    Levels of Vitamin E above 100 IU daily are associated with decreased risk of coronary heart disease and certain types of cellular disorders, as well as enhancement of immune function. These vitamin E intakes are considerably above levels obtainable from diet alone. 11,12,13

    ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES:

    This is a product that is Patent Pending, based on months of research into optimal forms, potencies and ratios of the 8 isomers of natural Vitamin E. All of the Vitamin E formulas currently on the market use potencies of tocopherols that are very dissimilar to what is found in a healthy diet, with either too low or too high amounts of gamma and alpha tocopherols for a good balance. Some do not even include tocotrienols.

    All of the Vitamin E formulas on the market that do contain a mixture of tocopherols and tocotrienols tend to use either 400 IU or 100 IU of alpha tocopherol, some as little as 50-60 IU, combined with varying doses of gamma tocopherol. We have reduced the alpha tocopherol from the standard 400 IU per capsule to 200 IU, allowing more gamma tocopherol in the capsule to follow the typical ratio in a healthy diet. Other brands either cut the alpha tocopherol too low (to keep the gamma tocopherol at a good level) or else cut the gamma and other tocopherols too low (to keep the alpha tocopherol at 400 IU).

    Special care was used to maintain a certain ratio of tocopherols and of tocotrienols that is unique and from natural sources. Our formula is also unique in mixing sources of tocotrienols to achieve our desired balance, whereas other formulas include only one source, despite the dissimilarity of the mixture to what is found in a healthy, varied diet.

    Other formulas use either Vitamin E derived from genetically engineered soybeans and/or add soybean oil from similar sources as a base. NOW uses expensive non-GMO sources, the first formula to do so, with no soybean oil added. This enhances the quality of our product compared to every other formula on the market.

    We use the expensive virgin palm oil rather than the cheap palm distillates because it is un-denatured and contributes additional, valuable oil nutrients such as CoQ10, Squalene and Sterols. Also, much of the clinical research done on tocotrienols was done using virgin palm oil sources 32

    Natural Vitamin E is more effective than synthetic Vitamin E.14 - 23

    SERVING SIZE & HOW TO TAKE IT: One or two capsules per day, preferably with meal(s). Oils enhance the absorption of Vitamin E. Concentrated fiber supplements may decrease the absorption of Vitamin E, so it is best not to take both at the same meal.

    SYNERGISTS: Antioxidants (Alpha Lipoic Acid, Vitamin C Complex, Pine or Grapeseed Extracts, VitaBerry Plus+, CoQ10, etc.), Plant Sterols, Fish Oil, Flaxseed Oil, GliSODin, EGCg Green Tea Extract, Lecithin, Nuts and Seeds

    CAUTIONS: None.

    SPECIFIC: Aspirin and blood thinners should not be taken with Vitamin E without physician’s approval. Many other pharmaceutical drugs deplete Vitamin E, adding to the likelihood that a person will be deficient.

    GENERAL: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. This document has not been reviewed by the FDA or by the company posting it. Information given here may vary from what is shown on the product label because this represents my own professional experience and understanding of the science underlying the formula and ingredients. When taking any new formula, use common sense and cautiously increase to the full dose over time.

    REFERENCES:

    1. Jiang Q, Christen S, Shigenaga MK, Ames BN (2001) g-Tocopherol, the major form of vitamin E in the US diet, deserves more attention. Am J Clin Nutr 74:714-722.
    2. Schneider C (2005) Chemistry and biology of vitamin E. Mol Nutr Food Res 49(1):7-30.
    3. Pfluger P, Kluth D, Landes N, Bumke-Vogt C, Brigelius-Flohe R (2004) Vitamin E: underestimated as an antioxidant. Redox Rep 9(5):249-254.
    4. Liu M, Wallin R, Saldeen (2002) Effect of mixed tocopherols on ecNOS, SOD, and PKC in leukocytes in human subjects. Nutr Res 22:1253-1263.
    5. Saldeen T, Li D, Mehta JL (1999) Differential Effects of a- and g-Tocopherol on Low-Density Lipoprotein Oxidation, Superoxide Activity, Platelet Aggregation and Arterial Thrombogenesis. J Am Coll Cardiol 34:1208-1215.
    6. "Packer L, Valacchi G. (2002) Antioxidants and the response of skin to oxidative stress: vitamin E as a key indicator. Skin Pharmacol Appl Skin Physiol 15(5):282-90."
    7. Sen CK, Khanna S, Roy S. (2004) Tocotrienol: the natural vitamin E to defend the nervous system? Ann N Y Acad Sci 1031:127-42.
    8. Dial S, Eitenmiller RR. 1995. Tocopherols and tocotrienols in key foods in the U.S. diet. In: Ong ASH, Niki E, Packer L, eds. Nutrition, Lipids, Health, and Disease. Champaign, IL: AOCS Press. Pp. 327–342.
    9. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids (2000). Institute of Medicine
    10. JASPREET K.C. AHUJA, JOSEPH D. GOLDMAN, and ALANNA J. MOSHFEGH. Current Status of Vitamin E Nutriture. Ann NY Acad Sci 2004 1031: 387-390.
    11. Bauernfeind, J. Tocopherols in Foods. In: Vitamin E: A Comprehensive Treatise. Marcel Dekker, Inc., New York and Basel, pp. 99-167, 1980.
    12. Horwitt, M.K. The Promotion of Vitamin E. J. Nutr. 116:1371-1377, 1986.
    13. Weber, P., Bendich, A. and Machlin, L.J. Vitamin E and Human Health: Rationale for Determining Recommended Intake Levels. Nutrition 13:450-460, 1997.
    14. Acuff RV et al. Am. J. Clin. Nutr. 1998;67:459-64
    15. Acuff RV et al, Am. J. Clin. Nutr. 1994, 60:397-402
    16. Behrens, W.A. and Madere, R. Tissue Discrimination between Dietary RRR-Alpha- and All-Rac-Alpha-Tocopherols in Rats. J. Nutr. 121:454-459, 1991.
    17. Burton G et al, Am. J. Clin. Nutr. 1998,67:669-84
    18. Ferslew, K.E., Acuff, R.V., Daigneault, E.A., Woolley, T.W. and Stanton, P.E. Pharmacokinetics and Bioavailability of the RRR and All Racemic Stereoisomers of Alpha-Tocopherol in Humans after Single Oral Administration. J. Clin. Pharmacol. 33:84-88, 1993.
    19. Horwitt, M.K. The Promotion of Vitamin E. J. Nutr. 116:1371-1377, 1986.
    20. Ogihara, T., Nishida, Y., Miki, M. and Mino, M. Comparative Changes in Plasma and RBC Alpha-Tocopherol after Administration of dl-Alpha-Tocopheryl Acetate and d-Alpha-Tocopherol. J. Nutr. Sci. Vitaminol. 31:169-177, 1985.
    21. Traber M et al, FEBS Letters 1998,437:145-148
    22. Traber MG, et al. J Lipid Res. 1990,31(4):675-85
    23. Weiser, H. and Vecchi, M. Stereoisomers of Alpha-Tocopheryl Acetate. II. Biopotencies of All Eight Stereoisomers, Individually or in Mixtures, as Determined by Rat Resorption-Gestation Tests. Internat. J. Vit. Nutr. Res. 52:351-370, 1982.
    24. Polidori MC, Mecocci P, Stahl W, et al. Plasma levels of lipophilic antioxidants in very old patients with type 2 diabetes. Diabetes Metab Res Rev 2000;16:15–9.
    25. Cooney RV, Franke AA, Harwood PJ, Hatch-Pigott V, Custer LJ, and Mordan LJ. gamma-Tocopherol Detoxification of Nitrogen Dioxide: Superiority to alpha-Tocopherol. PNAS 1993; 90: 1771-1775.
    26. Morris MC, Evans DA, Tangney CC, Bienias JL, Wilson RS, Aggarwal NT, Scherr PA. Relation of the tocopherol forms to incident Alzheimer disease and to cognitive change. Am J Clin Nutr. 2005 Feb;81(2):508-14. PMID: 15699242
    27. Inokuchi H, Hirokane H, Tsuzuki T, Nakagawa K, Igarashi M, Miyazawa T. Anti-angiogenic activity of tocotrienol. Biosci Biotechnol Biochem. 2003 Jul;67(7):1623-7. PMID: 12913317
    28. Kline K, Yu w, Sander BG, et al. Induction of apoptosis in human breast cancer cells by tocopherols and tocotrienols. (1999), Nutr Cancer, 33 : pp : 26 – 32
    29. The Chicago Health and Aging Project, Martha Clare Morris, Denis A Evans, Christine C Tangney, Julia L Bienias, Robert S Wilson, Neelum T Aggarwal and Paul A Scherr. Relation of the tocopherol forms to incident Alzheimer disease and to cognitive change. American Journal of Clinical Nutrition, Vol. 81, No. 2, 508-514, February 2005
    30. Parker RA, Pearce BC, Clark RW, Gordon DA, Wright JJ. Tocotrienols regulate cholesterol production in mammalian cells by post-transcriptional suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. J Biol Chem. 1993 May 25;268(15):11230-8. PMID: 8388388
    31. Pearce BC, Parker RA, Deason ME, Qureshi AA, Wright JJ. Hypocholesterolemic activity of synthetic and natural tocotrienols. J Med Chem. 1992 Oct 2;35(20):3595-606. PMID: 1433170
    32. Soelaiman IN, Ahmad NS, Khalid BA. Palm oil tocotrienol mixture is better than alpha-tocopherol acetate in protecting bones against free-radical induced elevation of bone-resorbing cytokines. Asia Pac J Clin Nutr. 2004 Aug;13(Suppl):



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    NOW is the leader in quality and value
    TopPreviousNext

    Date: October 21, 2005 08:12 AM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: NOW is the leader in quality and value

    NOW is the leader in quality and value

  • • NOW will often have the lowest price, and our quality and value is second to none.
  • • NOW offers specials every month granting retailers the opportunity to showcase extremely competitive products in many of the most popular categories.
  • • Compare our price on trademarked ingredients such as ester-c, 7-keto, Carnipure, Phase-2 and Relora to see how much money NOW can save you.

    “We only deal with companies that support the natural products industry and have a strong public service mission”

    We couldn’t agree more. NOW has, and will continue to fight for the rights of consumers to take safe supplements. As one of the most active and influential advocates in the natural products industry, we proudly support the following industry organizations.

    NFA, Citizens for health, AHPA, OTA, The Herb Research Foundation, The American Botanical Council, Consumers for Health Choice (UK), The GMO Task Force, The GMP Task Force, American Herbal Pharmacopoeia, The Campaign to label Genetically Engineered Foods, AOAC (method validation), AOCS (American Oil Chemist Society), The Dietary Supplement Education Alliance (DSEA), and More…

    “Does NOW support any Charitable or public services?”

    NOW is a leading recycling company and was awarded a silver medal for nutrition business journal in 2005 for our dedication to environmental and sustainability issues. We use environmental-friendly packaging and procedures to ensure that our impact on the environment is minimal. Here are just a few of the charities and originations NOW generously supports:

    Local Heal Clinics and food banks, Salvation Army, Marklund children’s home, African meal-a-day fund, compassion international, vitamin angel, world relief, Indian orphanage, Hephzibah children’s home, nature conservancy, Americas second harvest, world wild life, and many more

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    Results of GM Foods...
    TopPreviousNext

    Date: October 18, 2005 12:37 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Results of GM Foods...

    In a study in the early 1990’s rats were fed genetically modified (GM) Tomatoes, the rats refused to eat them. The rats were force fed and Several rats developed stomach leasions and seven out of 40 died within two weeks.

    Whats is GMO?

    GMO, Genetic Modified Organism, definition Genetic Modified Organisms according to the Gentechnikgesetz (GenTG)from 20.06.90 (Genetic Technique Law) in Germany are organisms whose genetical material were modified in a way which is not found in nature under natural conditions of crossbreed or natural recombination. The genetic Modified Organism must be a biological unit which is able to multiply itself or to transmit genetic material. Examples of modifications covered by this law are DNS recombination techniques in which vector systems are used; techniques by which genetic material prepared outside of the cell is introduced directly in the organism. These techniques include microinjection, macroinjection and micro encapsulation, cell fusion as well as hybridization procedures by which living cells are formed with a new combination of genetic material using methods which are not found under natural conditions.

    Rats fed GM corn had problems with blood cell formation and rats fed GM soy had problems with liver cell formation and livers of rats fed GM Canola had were heavy.

    Cows in germany were fed GM Corn died with out reason and pigs fed GM corn became steril.

    The more awareness a population has on GM foods the less the population trusts these types of foods, many Americans believe they have never eaten GM foods but little did they know they eat it daily, the long term effect of this sort of foods may take a decade of more to show up, do you want to take that chance? Not me.



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    Maintaining Healthy Veins
    TopPreviousNext

    Date: July 25, 2005 09:36 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Maintaining Healthy Veins

    More than 40 million Americans have varicose veins, a term in Latin meaning “twisted and wollen blood vessel.” Although the condition is rarely disabling, it is disfiguring, causing discomfort and embarrassment to those afflicted.

    many cases, genetic predisposition and gender determine who will develop varicose veins. A full 75% of Americans with the condition ar e women. At risk some women who may experience the beginning of this condition during pregnancy as the enlarging womb presses on the veins in the abdomen, increasing the pressure in the veins of the legs.

    Age is another factor as the skin becomes less elastic, lessening vein support. Some individuals are genetically edisposed to a malfunction of the one-way valves that may cause a back low of blood to pool in super ficial veins, stretching and swelling them.

    some health care professionals believe that our Western diet, high in refined carbohydrates and fat and low in fiber, may cause straining during bowel movement leading to hemorrhoids (anal varicose veins) and increase pressure on the leg veins. Our Western diet also eads to obesity and cardiovascular conditions such as plaque deposits in the arteries, abnormal clotting and platelet aggregation, cardiac dysfunction or failure, all leading to a weakened venous system that could increase the chance of developing varicose veins and edema (swelling in the legs). Those who ar e predisposed to varicose veins and who stand for long periods of time, especially on hard floors, may develop them more quickly.

    If you are at risk of developing this condition as you age, emphasizing a diet high in fiber, legumes and grains, fresh fruits and vegetables will improve your chances of maintaining good vein health. Other nutritional supplements that may be beneficial are horse chestnut seeds, Centella Asiatica, Milk Thistle, Butcher’s Broom and bioflavonoids.

    Horse chestnut seeds have a long historical use in the treatment of varicose veins and hemorrhoids. One active ingredient that has been researched is a saponin mixture called Aescin. In a recent study, Aescin was as effective as compression stockings in reducing leg swelling in patients with chronic venous insufficiency.

    Centella Asiatica is a common edible herb also known as Gotu Kola in India. When grown in Madagascar, it has a higher content of a compound called triterpenic fraction (TTFCA) than the same herb has when grown in other parts of the world. This compound has been used for many years in the treatment of venous hypertension. In a study conducted in 1989, 120mg dosage was safely used in patients with poor venous blood flow and it improved the condition after one or two months.

    Often, inflammation is a component of varicose veins. Milk Thistle, another herb commonly used for the treatment of liver disorders, was also found to reduce inflammation and edema in a recent Spanish study.

    A bushy ever green perennial found throughout much of the Western world is Butcher’s Broom. Its saponin glycosides ar e anti-inflammatory and helped contract blood vessels, especially veins thus making it an important component of any natural for mulation used to improve venous conditions.

    Certain bioflavonoids, such as quer cetin and rutin, have also been shown to be useful in the natural tr eatment of varicose veins as a strengthener of capillary and vein walls.

    There are other nutritional supplements including vitamins and minerals that may help maintain vein health as we age. They are listed in my new book “A Doctor’s Guide to Natural Medicine.” To improve vein health and to decrease your chance of developing varicose veins: do not stand for long periods of time especially on hard sur faces such as concrete. If you can’t avoid this, make sure your shoes are well cushioned. If you are sitting for long periods of time either working or traveling, take walking breaks. Stop crossing your legs and exercise regularly to incorporates rhythmical contraction of the leg muscles. Rest with your legs elevated when taking a break. W earing good support hose and avoiding tight knee-highs will promote good blood flow.

    These things can be very important if you ar e genetically pr edisposed to varicose veins. Starting nutrients early may help diminish or delay venous problems.

    Micromedex, Inc. Volume 96, 1974-1998. Diehmetal. Microcirculation Laboratory, Cardiovascular Clinic, Chieti, Italy.

    Efficacy of Centellase in the Treatment of Venous Hypertension Evaluated by a Combined Micro circulatory Model. G. Belcaroetal. Current Therapeutic Research, Vol. 46, No. 6, Dec. 1989.

    Effect of Silymarin on Different Acute Inflammation Models and on Leukocyte Migration. R. de la Puertaetal, J. Pharm. Parmacol. 1996, 48: 968-970 Merck Sciential Review, no. 10, 1995-04-30, pp. 2



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    Nature's Cancer fighters ...
    TopPreviousNext

    Date: July 07, 2005 12:36 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Nature's Cancer fighters ...

    Cancer has always been a word no one wants to hear from a doctor's lips. But as a fatal disease, cancer has gone from dread to worse, passing heart disease as the number-one killer of Americans under the age of 85 (a category that includes the overwhelming majority of us). While death rates for both illnesses has dropped over the past few years, the improvement has been much more pronounced for cardiovascular disorders.

    According to the American Cancer Society, 476,009 people died of cancer in 2002 (the last year for which statistics are available). Behind every one of those numbers is a web of lives tangled by cancer's relentless onslaught: A child who misses a mother's comforting arms, a bride without a father to walk her down the aisle, a spouse coming home to a dark, cold house every night. And for those fortunate enough to survive a cancer encounter, there's always the dark worry of recurrence that surfaces with every ache or twinge.

    Many people think of cancer as either a random calamity of a genetically driven inevitability, but it ain't necessarily so. Diet is coming up big as a major cancer-risk player: For example, eating a lot of red meat, especially highly processed meats such as bacon, has been linked to high colorectal cancer risk in an investigation published by the Journal of the American Medical Association. On the positive side, a number of nutrients have shown cancer-fighting power, such as the recently discovered link between the B vitamin folate and reduced risk of colon and other cancers (see page 57). Other useful nutrients appear on the chart that follows.

    Of course, risk always varies from person to person, and there are some lifestyle issues, like not smoking, that are no-brainers when it comes to cancer deterrence. But isn't it nice to know that protection from such a terrible disease might be as close as the end of your fork?

    Nature's Cancer fighters

    Berries

  • Description: Black or blue, rasp or straw, these tiny fruits pack a huge health punch; notable phytonutrients include anthocyanadins, ellagic acid and quercetin, along with vitamins and fiber.
  • Function: Among the plant world's most powerful antioxidants; have shown the ability to inhibit cancer cell growth.
  • Citrus Bioflavonoids

  • Description: These substances, found in oranges, lemons, limes and grapefruits, include hesperidin and limonene.
  • Function: Have shown promising anti-cancer effects in early studies; grapefruit compounds may be praticularly helpful in fighting lung cancer among smokers and colon cancer.
  • Curcumin

  • Description: A reddish yellow compound found in the spice turmeric, a staple in indian cookery.
  • Function: Interfers with cancer cell proliferation and with tumor blood-supply developement. Cooking use thought to be responsible for lower childhood cancer rates in asia.
  • EPA

  • Description: An Omega-3 acid found in such fatty fish as salmon and sardines; complete name: eiscosapentaenoic acid.
  • Function: Increased intake linked to reduced rates of several types of cancer, including those of the breast, colon, lung and prostate. May help make standard chemotherapy more effective (Consult your physician first).

    Green Tea

  • Description: Leaves of the Camilla sinensis plant, which is extensively cultivated in China, India and Japan; One of the world's most popular beverages that's also available in extract form.
  • Function: Contains potent antioxidants; has been associated with lower cancer rates in large population studies. Extract may make it more difficult for cancer cells to invade healthy tissues.
  • Lycopene

  • Description: Best known for putting the red in tomatoes, this phytonutrient is also found in apricots, pink grapefruit and watermelon.
  • Function: Associated with reduced risk of, and slower growth rates in, prostate cancer; recent research also links lycopene to lower pancreatic cancer risk. Reduces DNA damage in white blood cells.
  • Mushroom Polysaccarides

  • Description: Complex sugar compounds found in a variety of mushrooms, include shiitake, maitake, and reishi.
  • Function: Different polysaccarides have shown different anti-cancer effects in laboratory studies: Some fight tumor formation, others induce apoptosis. In Japan, mushroom eaters have lower cancer death rates.
  • Selenium

  • Description: Trace mineral found in grains, meats, seafood and some nuts, most notably brazil nuts. If using supplements, follow package directions.
  • Function: Supports production of glutathione, a natural antioxidant. Has reduced prostate cancer risk in men with low blood selenium levels. May lower colon cancer risk.
  • Soy

  • Description: Soy foods include soy milk, tempeh, edamame (Vegetable green soybeans) and tofu; also available as soy protein extract.
  • Function: Populations that consume high amounts of soy foods have lower breast and prostate cancer rates.
  • Vitamin C

  • Description: Found in citrus fruit, cabbage and related vegetables (broccoli, brussels sprouts,cauliflower), Potatoes, spinach, strawberries, tomatoes and tomato juice.
  • Function: The body's primary water-based antioxidant; has neutralized toxic byproducts of normal fat metabolism in some studies. Recharges its partner, Vitamin E.
  • Vitamin D

  • Description: While vitamin D is found in egg yolks, butter and cod liver oil, the main source is sun-exposed skin.
  • Function: Regular sun exposure is linked with lower overall cancer death rates, while rates for breast, colon and prostate cancers are all higher in northern parts of the US.
  • Vitamin E, Natural

  • Description: Found in almonds, fruit, peanuts, vegetable oils, whole grains (including brown rice).
  • Function: The body's primary fat-based antioxidant; may retard prostate cancer developement.
  • Glossary

  • Apoptosis - process by which cell normally die and are replaced; becomes disabled in cancer cells.
  • Antioxidant - counters harmful molecules called free radicals that can damage DNA, which can lead to cancer.
  • Phyonutrient - Substances found in plant foods that promote good health in humans.
  • Proliferation - unregulated growth and reproduction that characterizes cancer cells.
  • Tumor
  • - Solid mass formed by some cancers; capable of developing its own blood-vessel network.



    --
    Vitanet ®

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    REFERENCES
    TopPreviousNext

    Date: June 25, 2005 08:13 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: REFERENCES

    REFERENCES

    1 a. The Surgeon General’s “Nutrition and Health Report.” b. The Centers for Disease Control and Prevention’s “National Health and Examination Survey (NHANES III)” c. The National Academy of Science’s. Diet and Health Report: Health Promotion and Disease Objectives (DHHS Publication No. (PHS) 91-50213, Washington, DC: US Government Printing Office, 1990). e. Dietary Guidelines for Americans. 2 Rolls BJ. Carbohydrates, fats, and satiety. Am J Clin Nutr 1995; 61(4 Suppl):960S-967S. 3 McDowell MA, Briefel RR, Alaimo K, et al. Energy and macronutrient intakes of persons ages 2 months and over in the United States: Third National Health and Nutrition Examination Survey, Phase 1:1988-91. Advance data from vital and health statistics of the Centers for Disease Control and Prevention; No. 255. Hyattsville, Maryland: National Center for Health Statistics; 1994. 4 Center for Science in the Public Interest and McDonald’s Nutrition and You—A guide to Healthy Eating at McDonald’s: McDonald’s Corp,1991. 5 Bray GA. Appetite Control in Adults. In: Fernstrom JD, Miller GD eds. Appetite and Body Weight Regulation. Boca Raton: CRC Press, 1994:1-92. 6 Michnovicz JJ. How to Reduce Your Risk of Breast Cancer. New York: Warner Book Inc. 1994:54. 7 Carcinogens and Anticarcinogens in the Human Diet. National Research Council Report, National Academy of Sciences, 15 Feb. 1996. 8 Van Tallie TB. Obesity: adverse effects on health and longevity. Am J Clin Nutr 1979:32: 2723-33. 9 Somer E, M.A. R.D. Nutrition for Women. New York: Henry Hold and Company, 1993:273. 10 Swaneck GE, Fishman J. Covalent binding of the endogenous estrogen 16A-hydroxyestrone to estradiol in human breast concer cells: characterization and intranuclear localization. Proc Natl Acad Sci USA 1988:85;7831-5. 11 Colditz GA. Epidemiology of breast cancer. Findings from the nurses’ health study. Cancer1993;714:1480-9. 12 Hennen WJ. Breast Cancer Risk Reduction. The effects of supplementation with dietary indoles. Unpublished report 1992. 13 Deslypere BJ. Obesity and cancer. Metabolism 1995;44(93):24-7. 14 Somer E, M.A. R.D. Nutrition for Women. New York: Henry Hold and Company, 1993:281. 15 Whittemore AS, Kolonel LN, John M. Prostate cancer in relation to diet, physical activity, and body size in blacks, whites, and Asians in the United States and Canada. J Natl Cancer Inst 1995;87(9):629-31. 16 Key T. Risk factors for prostate cancer. Cancer Survivor 1995;23:63- 77. 17 Kondo Y, Homma Y, Aso Y, Kakizoe T. Promotional effects of twogeneration exposure to a high-fat diet on prostate carcinogenisis in ACI/Seg mice. Cancer Res 1994;54(23):6129-32. 18 Wang Y, Corr JG, Taler HT, Tao Y, Fair WR, Heston WD. Decreased growth of established human prostate LNCaP tumors in nude mice fed a low-fat diet. J Natl Cancer Inst. 1995;87(19):1456-62. 19 Nixon DW. Cancer prevention clinical trials. In-Vivo 1994;8(5):713-6. 20 Key T. Micronutrients and cancer aetiology: the epidmiological evidence. Proceed Nutr Soc 1994;53(3):605-14. 21 Gorbach SL, Goldin BR. The intestinal microflora and the colon cancer connection. Reviews of Infectious Diseases 1990;12(Suppl 2):S252-61. 22 Shrapnel WS, Calvert GD, Nestel PJ, Truswell AS. Diet and coronary heart disease. The National Heart Foundation of Australia. Med J Australia. 1995;156(Suppl):S9-S16. 23 Ellis JL, Campos-Outcalt D. Cardiovascular disease risk factors in native Americans: a literature review. Am. J. Preventive Med 1994;10(5):295-307. 24 DiBianco R. The changing syndrome of heart failure: an annotated review as we approach the 21st century. J. Hypertension 1994; 12(4 Suppl):S73- S87. 25 Van Itallie TB. Obesity: adverse effects on health and longevity. Am J Clin Nutr 1979;32(suppl):2723-33. 26 Kestin M, Moss R, Clifton PM, Nestel PJ. Comparative effects of three cereal brans on plasma lipids, blood pressure and glucose metabolism in mildly hyper-cholesterolemic men. Am J Clin Nutr 1990;52(4):661-6. 27 Story JA. Dietary fiber and lipid metabolism. In: Spiller GA, Kay RM. eds. Medical Aspects of Dietary Fiber. Penun Medical; New York, 1980, p.138. 28 Stein PP, Black HR. The role of diet in the genesis and treatment of hypertension. Med. Clin. North America. 1993;77(4):831-47. 29 Olin JW. Antihypertensive treatment in patients with peripheral vascular disease. Cleve. Clin. J. Medicine. 1994;61(5):337-44. 30 Tinker LF. Diabetes Mellitus—a priority health care issue for women. J. Am. Dietetic Association. 1994;94(9):976-85. 31 Gaspard UJ, Gottal JM, van den Brule FA. Postmenopausal changes of lipid and glucose metabolism: a review of their main aspects. Maturitas. 1995;21(3):71-8. 32 Coordt MC, Ruhe RC, McDonald RB. Aging and insulin secretion. Proc. Soc. Exp. Biology and Medicine. 1995;209(3):213-22. 33 Felber JP. From Obesity to Diabetes. Pathophysiological Considerations. Int. Journal of Obesity 1992;16:937-952. 34 Gillum RF. The association of body fat distribution with hypertension, hypertensive heart disease, coronary heart disease, diabetes, and cardiovascular risk factors in men and women age 18-79. J Chronic Diseases 1987;40:421-8. 35 Haffner SM, Stern MP, Hazuda HP, et al. Role of obesity and fat distribution in non-insulin-dependent diabetes mellits in Mexican Americans and non- Hispanic whites. Diabetes Care 1986;9:153-61. 36 Bonadonna RC, deFronzo RA. Glucose metabolism in obesity and type 2 diabetes. Diabetes and Metabolism. 1991;17(1 Pt. 2):12-35. 37 Shoemaker JK, Bonen A. Vascular actions of insulin in health and disease. Canadian J. of Applied Physiology. 1995;20(2):127-54. 38 Resnick LM. Ionic Basis of Hypertension, Insulin Resistaince, Vascular Disease, and Related Disorders. The Mechanism of ‘Syndrome X’. Am. J. Hypertension. 1993;6(suppl):123S-134S. 39 Trautwein EA. Dietetic influences on the formation and prevention of cholesterol gallstones. Z. Ernahrugswiss. 1994;33(1):2-15. 40 Cicuttini FM, Spector TD. Osteoarthritis in the aged. Epidemiological issues and optimal management. Drugs and Aging. 1995;6(5):409-20. 41 Melnyk MG, Wienstein E. Preventing obesity in black women by targeting adolescents: a literature review. J Am. Diet. Association. 1994;94(4):536-40. 42 Robinson BE, Gjerdingen Dk, Houge DR. Obesity: a move from traditional to more patient-oriented management. J. Am. Board of Family Practice. 1995;8(2):99-108. 43 Dulloo AG, Miller DS. Reversal of Obesity in the Genetically Obese fa/fa Zucker Rat with an Ehpedrine/Methylxanthines Thermogenic Mixture. J. Nutrition. 1987;117:383-9. 44 Dulloo AG, Miller DS. The thermogenic properties of ephedrin/methylxanthine mixtures: animal studies. Am J Clinical Nutr. 1986;43:388-394. 45 Richelsen B. Health risks of obesity. Significance of the regional distri-bution of adipose tissue. Ugeskr. Laeger. 1991;153(13):908-13. 46 Lissner L, Heitmann BL. Dietary fat and obesity: Evidence from epidemiology. European J. Clinical Nutrition. 1995;49(2):79-90. 47 Lissner L, Heitmann BL. The dietary fat: Carbohydrate ratio in relation to body weight, Current Opinion in Lipidology. 1995;6(1):8-13. 48 Ravussin E. Energy metabolism in obesity. Studies in the Pima Indians. Diabetes Care. 1993;16(1):232-8. 49 O’Dea K. Westernisation, insulin resistance and diabetes in Australian aborigines. Med J. Australia. 1991;155(4):258-64. 50 Bailey C. Fit or Fat . Houghton Mifflen, Boston, 1991. 51 McCarty MF. Optimizing Exercise for Fat Loss. Unpublished report. 52 Weinsier RL, Schutz Y, Bracco D. Reexamination of the relationship of resting metabolic rate and fat-free mass and the the metabolically active components of fat-free mass in humans. Am. J. Clinical Nutrition. 1992;55(4):790-4. 53 Evans WJ. Exercise, nutrition and aging. J. Nutrition. 1992;122(3 suppl):796-801. 54 Schlicker SA, Borra ST, Regan C. The weight and fitness status of United States children. Nutrition Reviews. 1994;52(1):11-7. 55 Raben A, Jensen ND, Marckmann P, Sandstrom B and Astrup A. Spontaeous weight loss during 11 weeks’ ad libitum intake of a low fat/high fiber diet in young, normal weight subjects. Stockholm Press. 1995;916-23. 56 Blundell JE, Cotton JR, Delargy H, Green S, Greenough A, King NA, Lawton, CL. The fat paradox: fat-induced satiety signals versus high fat overconsumption. Short Communication 1995:832-835. 57 Reinhold RB. Late results of gastric bypass surgery for morbid obesity. J Am Coll Nutr 1994;13(4):307-8. 58 McCredie M, Coates M Grulich A. Cancer incidence in migrants to New South Wales (Australia) from the Middle East, 1972-1991. Cancer Causes Control 1994:5(5):414-21. 59 Schiff ER, Dietschy JM. Steatorrhea Associated with Disordered Bile Acid Metabolism. Am. J. Digestive Diseases. 1969;14(6) 60 Nauss JL , Thompson JL and Nagyvary J. The binding of micellar lipids to Chitosan. Lipids. 1983;18(10):714-19. 61 Braconnot H, Sue la natrue ces champignons. Ann Chim Phys 1811;79:265. 62 Odier A. Memoire sur la composition chemique des parties cornees des insectes. Mem Soc Hist Nat Paris 1823;1:29. 63 Johnson EL, Peniston QP. Utilization of shellfish waste for chitin and Chitosan production. Chp 19 In: Chemistry and Biochemistry of Marine Food Products. Martin RE, Flick GJ, Hebard CE and Ward DR (eds.) 1982. p.415-. AVI Publishing Co., Westport, CT. 64 Shahram H. Seafood waste: the potential for industrial use. Kem Kemi 1992;19(3),256-8. 65 Rouget C. Des substances amylacees dans le tissue des animux, specialement les Articules (Chitine). Compt Rend 1859;48:792. Commission on Natural Health Products. 1995 67 Peniston QP and Johnson EL. Method for Treating an Aqueous Medium with Chitosan and Derivatives of Chitin to Remove an Impurity. US Patent 3,533,940. Oct. 30:1970. 68 Poly-D-Glucosamine (Chitosan); Exemption from the Requirement of a Tolerance. Federal Register. 1995;60(75):19523-4. Rules and Regulations. Environmental Protection Agency 40 CFR Part 180. April, 19, 1995. 69 Arul J. “Use of Chitosan films to retard post-harvest spoilage of fruits and vegetables,” Chitin Workshop. ICNHP, North Carolina State University, Raleigh, NC. 70 Karlsen J, Skaugrud O. “Excipient properties of Chitosan,” Manufacturing Chemist. 1991;62:18-9. 71 Winterowd JG, Sandford PA. Chitin and Chitosan. In: Food Polysaccharides and their Applications. Ed: Stephen AM. Marcel Dekker 1995. 72 Chitin Workshop. ICNHP, North Carolina State University, Raleigh, NC. 73 Advances in Chitin and Chitosan. Eds: CJ Brine, PA Sandford, JP Zikakis. Elsevier Applied Science. London. 1992. 74 Chitin in Nature and Technology. Eds: R Muzzarelli, C Jeuniaux, GW Gooday. Plenum Press, New York. 1986. 75 Zikakis, JP. Chitin, Chitosan and Related Enzymes. Academic Press, Inc. 1984. 76 Abelin J and Lassus A. Fat binder as a weight reducer in patients with moderate obesity. ARS Medicina, Helsinki, Aug- October, 1994. 77 Kanauchi O, Deuchi K, Imasato Y, Shizukuishi M, Kobayashi E. Increasing effect of a Chitosan and ascorbic acid mixture on fecal dietary fat excretion. Biosci Biotech Biochem 1994;58(9):1617-20. 78 Maezaki Y, Tsuji K, Nakagawa Y, et al. Hypocholesterolemic effect of Chitosan in adult males. Biosci Biotchnol Biochem1993;57(9):1439-44. 79 Kobayashi T, Otsuka S, Yugari Y. Effect of Chitosan on serum and liver cholesterol levels in cholesterol-fed rats. Nutritional Rep. Int., 1979;19(3):327-34. 80 Sugano M, Fujikawa T, Hiratsuji Y, Hasegawa Y. Hypocholesterolemic effects of Chitosan in cholesterol-fed rats. Nutr Rep. Int. 1978;18(5):531-7. 81 Vahouny G, Satchanandam S, Cassidy M, Lightfoot F, Furda I. Comparative effects of Chitosan and cholestryramine on lymphatic absorption of lipids in the rat. Am J Clin Nutr, 1983;38(2):278-84 82 Suzuki S, Suzuki M, Katayama H. Chitin and Chitosan oligomers as hypolipemics and formulations containing them. Jpn. Kokai Tokkyo Koho JP 63 41,422 [88,422] 22 Feb1988. 83 Ikeda I, Tomari Y, Sugano M. Interrelated effects of dietary fiber on lymphatic cholesterol and triglyceride absorption in rats. J Nutr 1989;119(10):1383- 7. 84 LeHoux JG and Grondin F. Some effects of Chitosan on liver function in the rat. Endocrinology. 1993;132(3):1078-84. 85 Fradet G, Brister S, Mulder D, Lough J, Averbach BL. “Evaluation of Chitosan as a New Hemostatic Agent: In Vitro and In Vivo Experiments In Chitin in Nature and Technology. Eds: R Muzzarelli, C Jeuniaux, GW Gooday. Plenum Press, New York. 1986. 86 Malette W, Quigley H, Gaines R, Johnson N, Rainer WG. Chitosan A New Hemostatic. Annals of Thorasic Surgery. 1983;36:55. 87 Malette W, Quigley H, Adickes ED. Chitosan effect in Vascular Surgery, Tissue Culture and Tissue Regeneration. In R Muzzarelli, C Jeuniaux, GW Gooday, Eds: Chitin in Nature and Technology. Plenum Press, New York. 1986. 88 Okamoto Y, Tomita T, Minami S, et al. Effects of Chitosan on experimental abscess with Staphylococcus aureus in dogs. J. Vet. Med., 1995;57(4):765-7. 89 Klokkevold PR, Lew DS, Ellis DG, Bertolami CN. Effect of Chitosan on lingual hemostasis in rabbits. Journal of Oral-Maxillofac-Surg, 1991;Aug. 49(8):858-63. 89 Surgery, Tissue Culture and Tissue Regeneration. In Chitin in Nature and Technology. Eds: R Muzzarelli, C Jeuniaux, GW Gooday. Plenum Press, New York. 1986. 90 Hiroshi S, Makoto K, Shoji A, Yoshikazu S. Antibacterial fiber blended with Chitosan. Sixth International Conference on Chitin and Chitosan. Sea Fisheries Institute, Gdynia, Poland. August 1994;16-19. 91 Shimai Y, Tsukuda K, Seino H. Antiacne preparations containing chitin, Chitosan or their partial degradation products. Jpn. Kikai Tokkyo Koho JP 04,288,017 [92,288,017] 13 Oct 1992. 92 Suzuki K, Okawa Y, Suzuki S, Suzuki M. Candidacidal effect of peritoneal exudate cells in mice administered with chitin or Chitosan: the role of serine protease in the mechanism of oxygen-independent candidacidal effect. Microbiol Immunol. 1987;31(4):375-9. 93 Sawada G, Akaha Y, Naito H, Fujita M. Synergistic food preservatives containing organic acids, Chitosan and citrus seed extracts. Jpn, Kokai Kokkyo Koho JP 04 27,373 [92 27,373] 30 Jan 1992. 94 Min H-K, Hatai K, Bai S. Some inhibitory effects of Chitosan on fishpathogenic oomycete, Saprolegnia parasitic. Gyobyo Kenkyu, 1994;29(2):73-4. 95 Nelson JL, Alexander JW, Gianotti L, Chalk CL, Pyles T. The influence of dietary fiber on microbial growth in vitro and bacterial translocation after burn injury in mice. Nutr 1994;10(1):32-6. 96 Ochiai Y, Kanazawa Y. Chitosan as virucide. Jpn Kokai Tokkyo Koho 79 41,326. 97 Hillyard IW, Doczi J, Kiernan. Antacid and antiulcer properties of the polysaccharide Chitosan in the rat. Proc Soc Expl Biol Med 1964; 115:1108-1112. 98 Shibasaki K, Sano H, MatsukuboT, Takaesu Y. pH response of human dental plaque to chewing gum supplemented with low molecular Chitosan. Bull- Tokyo-Dent-Coll, 1994:35(2): 61-6. 99 Kato H, Okuda H. Chitosan as antihypertensive. Jpn. Kikoi Tokyo Koho JP 06 56,674 [94 56,674] 100 Kato H, Taguchi T. Mechanism of the rise in blood pressure by sodium chloride and decrease effect of Chitosan on blood pressure. Baiosaiensu to Indasutori 1993;51(12):987-8. 101 Muzzarelli R, Biagini G, Pugnaoni A, Filippini O, Baldassarre V, Castaldini C, and Rizzoli C. Reconstruction of Periodontal Tissue with Chitosan. Biomaterials. 1989;10:598-603. 102 Sapelli P, Baldassarre V, Muzzarelli R, Emanuelli M. Chitosan in Dentistry. In Chitin in Nature and Technology. Eds: R Muzzarelli, C Jeuniaux, GW Gooday. Plenum Press, New York. 1986. 103 Borah G, Scott G, Wortham K. Bone induction by Chitosan in endochrondral bones of the extremities. In Advances in Chitin and Chitosan. Eds: CJ Brine, PA Sandford, JP Zikakis. Elsevier Applied Science. London. 1992. 104 Ito F. Role of Chitosan as a supplementary food for osteoporosis. Gekkan Fudo Kemikaru, 1995;11(2):39-44. 105 Nakamura S, Yoshioka T, hamada S, Kimura I. Chitosan for enhancement of bioavailability of calcium. Jpn. Kokai Tokkyo Koho JP 07 194,316 [95 194,316] 01 Aug 1995. 106 Maekawa A, Wada M. Food Containing chitin or its derivatives for reduction of blood and urine uric acid. Jpn. Kokai Tokkyo Koho JP 03 280,852 [91 280,852], 11 Dec 1991. 107 Weisberg M, Gubner R. Compositions for oral administration comprising Chitosan and a pharmaceutically acceptable carrier. Antacid preparations for alleviating gastric hyperacidity. U.S. patent 3257275 108 Kanauchi O, Deuchi K, Imasato Y, Shizukuishi M, Kobayashi E. Mechanism for the inhibition of fat digestion by Chitosan and for the synergistic effect of ascorbate. Biosci Biotech Biochem1995;59(5):786-90. 109 McCausland CW. Fat Binding Properties of Chitosan as Compared to Other Dietary Fibers. Private communication. 24 Jan1995. 110 Deuchi K, Kanauchi O, Imasato Y, Kobayashi E. Biosci Biotech Biochem. 1994:58,1613-6. 111 Ebihara K, Schneeman BO. Interaction of bile acids, phospholipids, cholesterol and triglyceride with dietary fibers in the small intestine of rats. J Nutr 1989;119(8):1100-6. 112 Weil A, M.D. Natural Health Natural Medicine: Boston: Houghton Mifflin, 1990:182. 113 Chen Y-H, Riby Y, Srivastava P, Bartholomew J, Denison M, Bjeldanes L. Regualtion of CYP1A1 by indolo[3,2-b]carbazole in murine hepatoma cells. J Biol Chem 1995;270(38):22548-55. 114 Intestinal Absorption of metal ions and chelates. Ashmead HD, Graff DJ, Ashmead HH. Charles C Thomas, Springfield, IL 1985. 115 Nutrient Interactions. Bodwell CE, Erdman JW Jr. Marcel Dekker New York 1988. 116 Heleniak EP, Aston B. Prostaglandins, Brown Fat and Weight Loss. Medical Hypotheses 1989;28:13-33. 117 Connor WE, DeFrancesco CA, Connor SL. N-3 fatty acids from fish oil. Effects on plasma lipoproteins and hypertriglyceridemic patients. Ann NY Acad Sci 1993;683:16-34. 118 Conte AA. A non-prescription alternative in weight reduction therapy. The Bariatrician Summer 1993:17-19. 119 McCarty MF. Inhibition of citrate lyase may aid aerobic endurance. Unpublished manuscript. 120 Bray GA. Weight homeostasis. Annual Rev Med 1991;42:205-216. 121 Dulloo AG, Miller DS. The thermogenic properties of Ephedrin/Methylxanthine mixtures: Human studies. Intl J Obesity 986;10:467-481. 122 Arai K, Kinumaki T, Fujita, T. Bulletin Tokai Regional Fisheries Res Lab. 1968;No. 56. 123 Bough WA. Private communication. 124 Freidrich EJ, Gehan, EA, Rall DP, Schmidt LH, Skipper HE. Cancer Chemotherapy Reports 1966;50(4):219-244. 125 A Drovanti, AA Bignamini, AL Rovati. Therapeutic activity of oral glucosamine sulfate in osteoarthritis: A placebo-controlled double-blind investigation. Clinical Therapeutics 1980;3(4):260-272. 126 K Deuchi, O Kanauchi, M Shizukuishi, E Kobayashi. Continuous and massive intake of Chitosan affects mineral and fat-soluble vitamin status in rats fed on a high-fat diet. Biosci. Biotech. Biochemistry. 1995;59(7):1211-6. 127 . BesChitin W in Chitin Wound Healing (video), Unitika Corporation, April 1992.

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    Fats and Oils: Clearing the Confusion
    TopPreviousNext

    Date: June 21, 2005 05:31 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Fats and Oils: Clearing the Confusion

    Fats and Oils: Clearing the Confusion

    By Fred Pescatore, M.D.

    Aside from tax forms, it's hard to find anything more confusing to consumers than fats and oils. Fat-free diehards still don't know that fat is essential for the brain, hormones, cellular membranes: life itself. The clueless still use shortening, margarine and damaged grocery store vegetable oils. But what worries me more is that supposedly educated consumers aren't even getting it right. Should we be surprised since their doctors probably don't know the truth?

    Mistakes made by your customers. They:

  • * Don't know monounsaturated fats are the key to health.
  • * Think olive oil is the healthiest choice.
  • * Buy junk olive oil without knowing it.
  • * Make olive oil toxic with misuse.
  • * Use grapeseed oil for its smoke point without regard to its pro-inflammatory fatty acids.
  • * Think all polyunsaturated fats are created equal.
  • * Believe flax oil is just the same as fish oil.
  • * Think healthy oil must be heavy and flavorless or strongly flavored.
  • * Don't know that oil has zero carbs.
  • * Don't know that all oils have the same number of calories.

    Let's clear up these myths so consumers can get busy being confused about something else:

  • * A compelling number of studies clearly demonstrate that we should get about 80% of our fats as monounsaturated fats, a key to the health benefits of the Mediterranean diet. Monounsaturated fats (omega 9) have been shown to lower total cholesterol, increase HDL, improve blood sugar management and help prevent cancer.
  • * Properly prepared olive oil is a decent choice because it is relatively high (around 70%) in monounsaturated fats. However, macadamia nut oil is much higher (84%). Macadamia nut oil is also lower in saturated fat and significantly higher in vitamin E, already making it a healthier choice.
  • * Any time something becomes quite popular, pretenders ride the wave. It is beyond suspicious that more Italian olive oil is sold than is actually produced. Much of what consumers think is "Extra Virgin" olive oil is actually a blend of refined olive (health benefits dramatically reduced) and even other oils (hmm, allergies anyone?). I review this in greater detail in The Hamptons Diet, my latest book, due out in May. For increasingly obvious reasons, the specific oil I recommend in it is MacNut™ Oil. It is the genuine article and the only product processed in the plant in Australia so there is no chance of contamination with another nut. This is a premium oil with processing quite superior to that from other countries.
  • * Overheating oil causes the formation of toxic free radicals and trans fats. Many don't realize that olive oil's smoke point is only 300-325:; so grilling, stir-fry and even baking become problematic. MacNut™ Oil is blessed with a 410: smoke point and great shelf stability.

  • * Grapeseed oil is 74% polyunsaturated omega 6. If that doesn't concern you, please read the next section.
  • * Recall that omega 3 and omega 6 fats, both polyunsaturated, have relatively opposite effects. Among the many virtues of omega 3, is that it is anti-inflammatory. The majority of omega 6 is pro-inflammatory. Yes, omega 6 is the source of beneficial GLA. However, GLA is just a very tiny variant the body should make if all circumstances are right. Our Paleolithic ancestors ate a diet that balanced the 3's and 6's ideally at 1:1. Now, because of vegetable oil use, junk food and animal feeding practices, Americans consume a 20:1 imbalance of pro-inflammatory omega 6. My recent book, The Allergy and Asthma Cure, tells more about the many health conditions worsened by inflammation. Now you can see that grapeseed oil is literally adding fuel to the fire. In MacNutTM Oil, the 3's and 6's are 1:1, as nature intended.
  • * Flax oil is great stuff if you buy it fresh, keep it cold and use it promptly. However, the EPA and DHA we prize so much in fish oil is not present in flax oil. To convert omega 3 to EPA and DHA, first be genetically adept and then avoid illness, age, stress, alcohol, aspirin, bad fats or sugar and deficiencies of the B's, C, Zinc and Magnesium. The same factors affect conversion of omega 6 into GLA.
  • * Some consumers have become accustomed to flavorless oils. Others grin and bear food that all tastes like olives. (Good olive oil tastes like olives.) Yet another reason I head the Scientific Advisory Panel for MacNutTM Oil is that it delicious cold or hot. It enhances recipes with a buttery richness but doesn't mask other ingredients.
  • * How can we tell consumers and not sound sassy that all oils are all zero carbs. They are oils, okay? There are only 3 classes of macronutrients: proteins, fats and carbs.
  • * Likewise, oil is oil when it comes to calories. Even 10-W-40 has 9 calories per gram. Protein and sugar are about half that. What is important is the type of fat in the oil and monounsaturated is the best.

    I hope this helps you educate consumers about the proper use of fats. Unfortunately, that still leaves a long list of other things they've been misled about.



    --
    Vitanet ®

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    Certified Foods
    TopPreviousNext

    Date: June 12, 2005 01:59 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Certified Foods

    Certified Foods by Glenda Olsen Energy Times, July 13, 2003

    What's in your food, and where does it come from? To most American consumers, that question may seem unimportant. But the answers might surprise you. Your food's origin and processing can make a big difference in its nutritional value, for better and for worse. Increasingly, concern over the quality of food and its influence on health are persuading shoppers to take a greater interest in their food. The result: More visits to natural food stores and more sales of organic food.

    Once upon a time, food used to be just food. Crops were grown on family farms, and animals were raised in barnyards. But today, corporations have conquered food production in a big way. Agribusiness is just that-a big business in which animals and plants are treated like assembly-line items and raised on factory farms.

    Organic Regulation

    While the term "organic" gets tossed around endlessly in the media, the term is often misconstrued. According to the United States Department of Agriculture (USDA), "Organic food is produced by farmers who emphasize the use of renewable resources and the conservation of soil and water to enhance environmental quality for future generations. Organic meat, poultry, eggs and dairy products come from animals that are given no antibiotics or growth hormones."

    In addition, organic farmers generally do not use pesticides, sewage sludge or synthetic fertilizers. This type of food is also produced without genetically modified organisms and is not subject to radiation used to zap the bugs on food. Today, USDA-approved certifying agents inspect the farms where organic food is raised to ensure organic standards are followed. In addition, the companies that process food and handle organic food have to be USDA-certified. Meeting these standards allows companies to use the USDA's organic label on foods that are at least 95% organic in origin. Labels for foods that contain between 70% and 95% organic content can use the words "Made With Organic Ingredients," but cannot use the seal.

    Solid Nutrition

    While the debate over the nutritional benefits of organic food has raged for decades, recent research is beginning to turn up evidence that organically grown fruits and vegetables may contain extra helpings of vitamins and other nutrients. A study at Truman State University in Kirksville, Missouri, found that organically grown oranges contain more vitamin C than conventional supermarket oranges (Great Lakes Regional Meeting, Amer Chem Soc, 6/02).

    Theo Clark, PhD, the Truman State professor who investigated the organic oranges, says that when he and his students began their research, "We were expecting twice as much vitamin C in the conventional oranges" because they are larger than organic oranges. To his surprise, chemical isolation combined with nuclear magnetic resonance (NMR) spectroscopy revealed that the organically grown oranges contained up to 30% more vitamin C than the conventionally grown fruits-even though they were only about half the size. "We speculate that with conventional oranges, (farmers) use nitrogen fertilizers that cause an uptake of more water, so it sort of dilutes the orange. You get a great big orange but it is full of water and doesn't have as much nutritional value," Dr. Clark says. "However, we can only speculate. Other factors such as maturity, climate, processing factors, packaging and storage conditions require consideration."

    Dodging Pesticides

    If you want to avoid pesticide residues in your food, research shows that going organic can make it much less likely that you or your family consumes these unwanted chemicals. Research, for instance, into the diets of children (Enviro Hlth Persp 3/03) shows that dining on organic fruits and vegetables, and organic juice, can lower kids' intake of pesticides.

    These scientists took a look at the organophosphorus (OP) pesticide breakdown products in the blood of kids ages two to five who ate conventional supermarket produce and compared it with the OP found in organic kids.

    The children on the organic diet had less OP in their blood than the other kids. As a matter of fact, the children on the conventional diet had six times the dimethyl metabolites, dimethyl being a pesticide suspected of affecting nerve function and growth. "Consumption of organic produce appears to provide a relatively simple way for parents to reduce their children's exposure to OP pesticides," note the researchers. "Organic foods have been growing in popularity over the last several years," says Jim Burkhart, PhD, science editor for the journal that published the study. "These scientists studied one potential area of difference from the use of organic foods, and the findings are compelling."

    GMO Development

    On the way to tonight's dinner, researchers have created genetically modified organisms (GMO), plants and animals that have been transgenically engineered. In the food world, that means organisms containing genes inserted from another species. Chances are if you eat food purchased at the typical supermarket, those comestibles contain GMO ingredients. In the United States, food companies are not required to label for GMO content.

    A growing number of American consumers are upset about not being told about the GMO products in their food. But industry scientists, worried that informed consumers may someday turn their back on GMO foods, consider consumer ignorance to be an acceptable state of affairs.

    For instance, the American Society of Plant Biologists (ASPB) is fighting regulations that would require GMO labeling. According to ASPB President Daniel Bush, PhD, of the University of Illinois at Urbana, "The language...(in these types of regulations) is based on a system of beliefs of what is 'natural,' rather than a scientifically defined set of criteria focused on content and nutritional value. This is a radical departure from food labeling up to now, which is designed to maximize useful information for consumers concerning what is in the food they are buying."

    Dr. Bush continues, "There are, of course, examples of voluntary labeling standards in the food industry that reflect how foods are processed, such as organic foods. The voluntary organic labeling standards were sought by the organic food industry. Kosher foods are also labeled as having been produced in accordance with specific beliefs. However, mandatory labeling of targeted production methods has never before been required and we believe would obscure rather than clarify important issues of food safety."

    In other words, Dr. Bush opposes GMO labeling because he feels it would unnecessarily stigmatize GMO food items. Others are not so sanguine about the safety of GMO foods.

    GMO Objections

    The arguments against GMO foods include:

  • * The genes from GMO plants may end up in weeds and other unintended species, creating superweeds that will be difficult to eradicate. Animals, such as fish on fish farms, may interbreed with animals in the wild and cause harmful changes.

  • * People may grow ill or die from unexpected allergies to GMO foods (NEJM 1996; 334(11):688-92).

  • * GMO plants may harm other wildlife, such as butterflies, that depends on pollen from these plants (Nature May 1999; 399(6733):214).

    These types of risks have motivated industry groups to urge more regulation of GMO crops. The Food Marketing Institute, the Grocery Manufacturers of America (GMA) and the National Restaurant Association, plus seven other food groups, are worried that GMO plants grown to produce pharmaceutical drugs could contaminate the food supply and destroy consumer trust in food.

    Mary Sophos, a vice president of GMA, warns, "To minimize the possible risks, a clear system of regulatory enforcement and liability needs to be in place. Until then, no permits for new field trials or for commercialization should be issued because there is no room for trial and error."

    These food industry groups have voiced their concerns to the Food and Drug Administration (FDA) and the USDA. Last year, the USDA forced ProdiGene Inc., a biotech firm, to dispose of 500,000 bushels of soybeans contaminated with a drug meant to treat diabetes. What are the chances of more GMO accidents? No one knows. But if you buy and eat organic, you minimize your risk and maximize your chances of dining on safer food.



    --
    Vitanet ®

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    Heart Science - A Five-Tiered Approach to Heart Health ...
    TopPreviousNext

    Date: June 02, 2005 12:07 PM
    Author: Darrell Miller (dm@vitanetonline.com)
    Subject: Heart Science - A Five-Tiered Approach to Heart Health ...

    Heart Science 30 tabs

    Your heart is crucial to every function of your body. It is the sole organ which pumps oxygen-rich blood through the entire circulatory system, feeding your cells and making life possible. Only recently are Americans realizing the importance of a proper low-fat diet, regular exercise, giving up cigarette smoking, and cutting down alcohol consumption to maintaining a healthy heart. Unfortunately, there has been a huge gap in the number of nutritional supplements which provide nutrients and herbs to support normal heart function. That’s where Source Naturals HEART SCIENCE comes in. Two years in the making, and backed by numerous scientific studies, the nutrients in HEART SCIENCE are some of the most soundly researched of all. Combining high potencies of these super-nutrients, HEART SCIENCE is the most comprehensive, cutting edge nutritional approach to proper heart care available.

    Source Naturals HEART SCIENCE— The Five Tiered Approach to Heart Health

    Your heart never rests. Even while you sleep, your heart must keep working, relying on the constant generation of energy by the body for its very survival. If this vital organ stops beating for even a short amount of time, all bodily functions cease and life ends. Source Naturals HEART SCIENCE helps support heart function on the chemical, cellular, structural, and energetic levels. This broad spectrum formula includes ingredients specifically geared for
    1) generating energy,
    2) decreasing harmful homocysteine levels,
    3) fighting oxidized cholesterol,
    4) maintaining the heart’s electrical rhythm, and
    5) protecting artery and capillary linings.

    Energy Generators for An Energetic Organ

    Every day, the human heart beats about 104,000 times, pumping over 8,000 liters of blood through the body! Because it requires so much energy to perform efficiently, the experts at Source Naturals included specialty nutrients in HEART SCIENCE such as Coenzyme Q10 and L-Carnitine — integral factors in the body’s energy production cycles — to enhance the body’s energy supply.

    There are three main interconnected energy generating cycles in our cells — the Glycolytic (sugar-burning) cycle, the Krebs’ (citric acid) cycle, and the Electron Transport Chain. Together they supply about 90 to 95% of our body’s entire energy supply, using fats, sugars, and amino acids as fuel. Coenzyme Q10 is one of the non-vitamin nutrients needed to maximally convert food into ATP (the energy producing molecule). It is the vital connecting link for three of the four main enzyme complexes in the Electron Transport Chain, the next step in energy generation after the Krebs’ cycle. Using the raw materials generated by the Krebs’ cycle, the Electron Transport Chain produces most of the body’s total energy! The heart is one of the bodily organs which contains the highest levels of CoQ10, precisely because it needs so much energy to function efficiently.

    CoQ10 is one of the most promising nutrients for the heart under investigation today. It has been postulated that as a result of its participation in energy production, CoQ10 improves heart muscle metabolism and the electrical functioning of the heart by enhancing its pumping capacity.8 Many factors such as a high fat diet, lack of exercise, and cigarette smoking can lead to suboptimal functioning of the heart, and therefore failure of the heart to maintain adequate circulation of blood. Interestingly, people whose lifestyles reflect the above factors also tend to have depleted levels of CoQ10 in the heart muscle.10

    Researchers suggest taking between 10-100 mg per day of CoQ10;18,29 HEART SCIENCE provides an impressive 60 mg of CoQ10 per 6 tablets. Similar to CoQ10, L-Carnitine is important for energy production in heart cells. It is a natural amino acid-like substance which plays a key role in transporting fatty acids, the heart’s main source of energy, to the mitochondria, the “power plants” of each cell, where they are utilized for the production of ATP. Heart and skeletal muscles are particularly vulnerable to L-Carnitine deficiency. Studies have shown that supplementation with LCarnitine improves exercise tolerance in individuals with suboptimal heart and circulatory function, and seems to lower blood lipid status and increase HDL (good) cholesterol.16, 22 Each daily dose of HEART SCIENCE contains 500 mg of this extremely important compound.

    Like CoQ10 and L-Carnitine, B Vitamins help improve the ability of the heart muscle to function optimally. Each B Vitamin, after being converted to its active coenzyme form, acts as a catalytic “spark plug” for the body’s production of energy. Vitamin B-1, for example, is converted to Cocarboxylase, which serves as a critical link between the Glycolytic and Krebs’ Cycles, and also participates in the conversion of amino acids into energy. A deficiency of B coenzymes within contracting muscle cells can lead to a weakened pumping of the heart.21

    HEART SCIENCE is formulated with high quantities of the most absorbable forms of B Vitamins providing maximum nutrition for the high energy demands of heart cells.

    Homocysteine Regulators

    B Vitamins also play a crucial role in the conversion of homocysteine, a group of potentially harmful amino acids produced by the body, to methionine, another more beneficial amino acid. While it is normal for the body to produce some homocysteine, even a small elevation in homocysteine levels can have negative implications. It is well documented that individuals who are genetically predisposed to having elevated homocysteine levels (homocysteinemics) tend to have excessive plaque accumulation in the arteries and premature damage to endothelial cells (cells lining the blood vessels and heart).26 Researchers have found that even those without this genetic abnormality, whose homocysteine levels are much lower than those of homocysteinemics, still have an increased risk for premature endothelial damage and the development of plaque in the arteries.24, 26 One study conducted among normal men and women found that those with the highest levels of homocysteine were twice as likely to have clogged arteries as were those with the lowest levels.24 Furthermore, it was found that the lower the research subjects’ blood levels of folate and B-6, the higher their homocysteine levels.24 Another study found that Folic Acid administered to normal men and women who were not even deficient in folate caused a significant reduction in plasma concentrations of homocysteine!3 In order to regulate homocysteine levels, it is critical to provide the body with sufficient amounts of B-6, B-12, and Folate, whether through the diet or through supplementation. HEART SCIENCE includes high levels of these three nutrients, providing B-6 in the regular and coenzyme form for maximum utilization.

    The Dangers of Oxidized LDL Cholesterol

    While many people have heard that high cholesterol levels may negatively affect normal heart function, few people understand exactly what cholesterol is, or how it can become harmful. Cholesterol is a white, waxy substance produced in the liver by all animals, and used for a variety of necessary activities in the body. Your liver also manufactures two main kinds of carrier molecules which transport cholesterol throughout the system: Low Density Lipoprotein (LDL) and High Density Lipoprotein (HDL). Cholesterol is either carried out by LDL from the liver to all tissues in the body where it is deposited, or carried back by HDLs which remove cholesterol deposits from the arteries and carry them to the liver for disposal. Because of this, LDL cholesterol is considered damaging, while HDL is considered protective. Problems occur when there is too much LDL cholesterol in the body and not enough HDL.

    When the body becomes overloaded with fat, an over-abundance of LDL particles are manufactured to process it, and they in turn become elevated in the body to a degree that the liver cannot handle. Rich in fatty acids and cholesterol, these particles are highly susceptible to free radical attack (oxidation). Once oxidized, LDL particles are no longer recognized by the body, which attacks them with immune cells. Immune cells which are bloated by oxidized lipids (called foam cells) are a key factor in the development of “fatty streaks” — the first sign of excess arterial fat accumulation. The bloated immune cells accumulate in artery lesions and create plaque in blood vessels, leading to obstruction and constriction of the vessels. Plus, these lodged foam cells continue to secrete free radicals into the bloodstream, making the problem worse.

    The development of lesions in the arteries is not an uncommon problem. Arterial (and all blood vessel) walls are composed of a chemical matrix which holds the endothelial cells in place. That endothelial layer is the first and most important line of defense in preventing large molecules, such as cholesterol and fat, from entering the vessel wall. This matrix is composed of proteins, collagen, elastin, and glycosaminoglycans (amino sugars). Arterial lesions can be caused by suboptimal collagen and elastin synthesis due to three factors: 1. Vitamin C deficiency (since Vitamin C is a key building block for collagen and elastin); 2. excessive consumption of rancid fats, or heavy usage of alcohol or cigarettes; and 3. free radical damage. Once these lesions are created, the body attempts to repair them by depositing LDL cholesterol — similar to the way one would patch a tire. If that cholesterol is not oxidized, i.e. chemically changed to a harmful, unstable molecule, then this process does not create a problem. But when arterial lesions are “patched” with foam cells, arterial walls suffer page 3 page 4 even more damage, because those foam cells release free radicals which can further damage cell membranes.

    Unfortunately, most people have a lot of oxidized cholesterol floating through the bloodstream. The typical American diet, with its low antioxidant intake and overconsumption of fried and overcooked foods, contributes to the overall levels of harmful oxidized cholesterol. In fact, the average American intake of antioxidants is low even by USRDA standards, making Americans particularly prone to having high levels of oxidized cholesterol.

    Cholesterol Fighters

    Fortunately, there are concrete steps you can take to prevent the oxidation of cholesterol, and its subsequent ill effects on health. In addition to cutting out high-cholesterol and fatty foods, supplementation can protect existing cholesterol and all tissue cells — from oxidation. Antioxidants, substances which scavenge and neutralize free radicals, protect the cardiovascular system by halting the oxidation of cholesterol, and helping to prevent plaque accumulation in the arteries and the continual secretion of free radicals by foam cells. Supplementing the diet with high amounts of Vitamin C, a key antioxidant, also encourages a more healthy “patching” of existing lesions by using collagen (made from Vitamin C) instead of cholesterol. HEART SCIENCE contains generous amounts of the following antioxidants for their protective benefits:

  • • Beta Carotene, a plant pigment, is the naturally occurring precursor to Vitamin A. When the body takes in high enough amounts of Beta Carotene, this lipid-soluble free radical scavenger concentrates in circulating lipoproteins and atherosclerotic plaques, where it performs its antioxidant functions. Beta Carotene is particularly unique and powerful as an antioxidant because it is capable of trapping a very toxic form of di-oxygen, called singlet oxygen, which can result in severe tissue damage. Beta Carotene is one of the most efficient quenchers of singlet oxygen thus far discovered. Six tablets of HEART SCIENCE provide an unprecedented 45,000 IU of Beta Carotene!
  • • Vitamin C is found in plasma, the watery component of blood, where it functions as a potent antioxidant. In addition to strengthening artery linings through collagen manufacture, Vitamin C is involved in the regeneration of Vitamin E within LDL particles. Vitamin C also plays an important role in the conversion of cholesterol into bile acids by the liver, a crucial step in reducing blood cholesterol levels. Once converted into bile acids, and then into bile salts, cholesterol can be excreted from the body, preventing build-up. Supplementation with Vitamin C may lower levels of LDL cholesterol and increase those of HDL cholesterol.25 It may also have a part in actually removing cholesterol deposits from artery walls — good news for people who are already experiencing plaque buildup.25 Each daily dose of HEART SCIENCE provides 1,500 mg of Vitamin C in its bioactive mineral ascorbate form.
  • • Vitamin E, together with Beta Carotene, protects lipids from free radical attack. It is the major antioxidant vitamin that is carried in the lipid fraction of the LDL particle, where it protects the LDL particle from damaging oxidation. Within an LDL particle, one molecule of Vitamin E has the ability to protect about 200 molecules of polyunsaturated fatty acids from free radical damage! Vitamin E also aids in protecting the heart by interfering with the abnormal clumping of blood cell fragments, called platelets, within blood vessels.4 It has been shown to inhibit the formation of thromboxanes and increase the production of prostacyclins, which together decrease abnormal platelet aggregation.11 A high potency of Vitamin E — 400 IU’s — is included in six tablets of HEART SCIENCE in the natural d-alpha succinate form, recognized by scientific researchers to be the most absorbable form!
  • • Selenium is an important mineral which has only recently gained attention. When incorporated into the enzyme Glutathione Peroxidase, it has highly powerful free radical-scavenging abilities, and has been shown to work synergistically with Vitamins A, C, and E. An essential mineral, Selenium used to be derived from eating foods grown in Selenium-rich soil. However, modern agricultural practices have depleted soil of its natural Selenium content, leaving many Americans deficient in this vital nutrient. Several epidemiological studies show that the incidence of advanced fatty deposits in blood vessels is much greater in individuals living in geographic areas of the United States and other parts of the world where the Selenium content of the soil is very low.27
  • Proanthodyn,™ an extract of grape seeds, is being called the most powerful antioxidant yet discovered. This highly potent, water-soluble bioflavonoid contains between 93-95% proanthocyanidins, the highest concentration of any nutrient available today. The protective actions of proanthocyanidins may help to prevent the development of plaque in artery walls by inhibiting the free radicals which are produced during the oxidation of cholesterol. The optimal daily amount (100 mg) of Proanthodyn is included in six tablets of HEART SCIENCE. In addition to the protective actions of antioxidants, several other nutrients can contribute to healthier cholesterol ratios.
  • • Chromium is a trace mineral which functions to aid the entrance of glucose into cells. Six tablets of HEART SCIENCE provide 300 mcg of Chromium in the form of Chromate® Chromium Polynicotinate and Chromium Picolinate — the most bioactive forms of Chromium. Not many people are familiar with the vital role Copper plays in the body. This trace mineral is found in all tissues of the body, and is particularly concentrated in the heart. Copper is part of several enzymes, and, in this capacity, is necessary for the development and maintenance of the cardiovascular system, including the heart, arteries, and other blood vessels. Because of its role in elastin production, Copper deficiency can severely damage blood vessels and heart tissue. In fact, researchers have found an inverse relationship between Copper status and increased risk for heart damage.10
  • • L-Proline and L-Lysine are two natural amino acids which show exciting promise in helping to prevent fatty deposits in blood vessels. Researchers have recently identified a particle associated with LDL called apoprotein (a) which is believed to be a main culprit in plaque development. 17 Scientific investigation has revealed that the lipoprotein (a) particle has an adhesive quality that makes the lipoprotein fat globule stick inside blood vessels. The sticky fat globules accumulate, leading to fatty deposits in blood vessels and the subsequent clogging of the arteries. L-Proline and L-Lysine tend to form a barrierlike layer around the apoprotein (a) particle, helping to push it away from the blood vessel wall, and impeding deposit.21

    The Regulating Trio

    Three nutrients — Magnesium, Potassium, and Taurine — work closely together in the body to help maintain the normal electrical rhythm of the heart, promote proper fluid balance, and prevent excessive Calcium levels from building up in the heart and artery linings.

  • • Magnesium is one of the single most important nutrients for maintaining a healthy heart. It plays an extremely vital role in maintaining the electrical and physical integrity of the heart muscle. It has been well established that Magnesium deficiency predisposes humans to serious disruptions of normal cardiac rhythm. One theory is that because Magnesium has a relaxing effect on muscle tissue, inadequate Magnesium stores may make the coronary arteries more susceptible to muscle spasm.10 Too little Magnesium can cause a Calcium/Magnesium imbalance, which can lead to the influx of too much Calcium into heart cells, and potentiate spasms in heart tissue. Another point for consideration is that because it relaxes the blood vessels, Magnesium keeps these vessels open, allowing for maximum blood flow to the heart. Magnesium also has the unique ability to stop unnecessary blood clotting by helping to reduce platelet adhesion.31 Blood clots are naturally produced by the body as a protective device to stop excessive blood flow when the body is injured. The clotting response happens when the body senses that the normally smooth blood vessel linings are rough, indicating that there is a cut. However, sometimes the body mistakes the rough surface of plaque-covered arteries as cuts, and creates unnecessary blood clots. Or, if a high fat meal has just been eaten, tiny fat globules called chylomicrons enter the bloodstream and can cause platelets to become abnormally sticky, possibly creating clots. When these clots flow through the bloodstream and reach a part of the artery which has plaque buildup, normal blood flow is blocked, and the amount of blood which reaches the heart is severely compromised. Magnesium is also crucial for the entrance of Potassium — a key mineral for many bodily functions — into the cells. Even if the body’s Potassium stores are high, without enough Magnesium, the Potassium will not be able to enter the cells and be utilized by the body. 300 mg of Magnesium (75% of the U.S.RDA) are contained in each daily dose of HEART SCIENCE. Along with Magnesium, Potassium helps to regulate normal heartbeat and blood pressure, and is necessary for the contraction and relaxation of muscle tissue. Potassium and Sodium are present in all body fluids; Potassium is found primarily within cell fluids, while Sodium is usually present in fluids surrounding cells. Together, they function to maintain the normal balance and distribution of fluids throughout the body. The body ideally should have a Potassium/Sodium balance of about 1:1; however, because the body holds onto Sodium, yet eliminates Potassium quickly, it is important that the dietary ratio of these two minerals be at least 3:1. Unfortunately, the typical American diet, with its emphasis on processed, salty (Sodiumrich) foods and lack of fresh fruits and vegetables, severely alters the body’s natural Potassium/ Sodium balance. Diets in the United States are extremely high in Sodium — sometimes containing as much as 15 times the recommended daily intake! A high Sodium/low Potassium diet interferes with the normal regulation of heartbeat and blood pressure, and has been linked with elevated blood pressure.25 Taurine is an amino acid which helps normalize electrical and mechanical activity of the heart muscle by regulating Potassium flux in and out of the heart muscle cells.

    Artery Lining Protectors

    Your arteries form an integral part of your cardiovascular system, carrying blood away from the heart to nourish other parts of the body. In a healthy heart, blood surges through the arteries with every beat of the heart. The arteries expand with each pulse to accommodate the flow of blood. When arteries become hardened and narrowed by the build-up of plaque, they can’t expand and are not able to transport blood efficiently throughout the body. This inability to open up increases blood pressure, putting a strain on the heart as well as the arteries. HEART SCIENCE includes ingredients specifically geared to protect against plaque formation within arteries and maintain the flexibility of these vital blood vessels. N-Acetyl Glucosamine (NAG) is a key amino sugar which forms the building blocks of mucopolysaccharides. Mucopolysaccharides, which are long chain sugars, are an integral component of connective tissue. They combine to form gel-like matrixes which are present throughout tissues in the body, helping to maintain the elasticity of blood vessels which must continually adapt to the changing pressures of blood flow. Each daily dose of HEART SCIENCE provides 500 mg — a substantial amount — of this vital tissue building block. There is evidence indicating that Silicon, a natural mineral, may protect against plaque formation in the arteries. Silicon is found mainly in connective tissues, where it helps bind the body’s chemical matrix. Bound Silicon is found in high amounts in arterial walls. Researchers have found that there is a steady decline in the Silicon content of the aorta and other arteries as we age. This may be due to the low fiber content of the typical American diet, since fiber is a key dietary source of Silicon.23 HEART SCIENCE includes 400 mg of Horsetail herb extract, a natural source of Silicon. Hawthorn Berry is without question the herb most widely used to encourage normal heart function. The beneficial actions of Hawthorn Berry on cardiac function have been repeatedly demonstrated in experimental studies. Supplementation with Hawthorn Berry has been shown to improve both the blood supply to the heart by dilating coronary vessels, and the metabolic processes in the heart, resulting in normal, strong contractions of the heart muscle.34 Also, Hawthorn may inhibit the angiotensen converting enzyme, which is responsible for converting angiotensen I to angiotensen II, a powerful constrictor of blood vessels.34 Bromelain, a natural enzyme derived from pineapples, has become well-known for its neuromuscular relaxing properties. Researchers have reported favorable results when using Bromelain for soothing vascular linings. Initial research also indicates that Bromelain may break down fibrin, the glue which holds platelets together to form blood clots.6

    Capillary Strengtheners

    Capillaries are the smallest, yet some of the most important, blood vessels. If you think of your cardiovascular system as a series of roads which transport blood and oxygen, then your arteries are akin to interstate highways, your arterioles are the main city boulevards, and your capillaries are local residential streets. Capillaries are so small, in fact, that single red blood cells actually have to fold up to fit through them. Because of their tiny size and the intricate nature of their network throughout the body, capillaries are responsible for actually nourishing each individual tissue cell! Along the length of the capillaries are small openings called slit pores through which oxygen, glucose, and nutrients leave the capillaries and enter the surrounding interstitial fluid. From there, they cross cell membranes and nourish the cells. Similarly, the waste products of cells enter the fluid and cross over into the capillaries, where they are then transported to the liver and kidneys for disposal. If the capillary slit pores are torn or have lesions, then blood proteins and Sodium will leak out and cause the interstitial fluid to take on a more gel-like nature. This makes the transfer of oxygen and nutrients to the cells more difficult, as well as the disposal of cell waste products, turning the fluid into a stagnant swamp instead of a flowing river. In addition to its powerful antioxidant actions, Proanthodyn also helps protect collagen and elastin, the main constituents of tissue in the capillaries, and throughout the body. It is absolutely essential for capillary walls — which are only one cell thick — to be strong and stable, so that they do not allow blood proteins to leak into the interstitial fluid. Once the interstitial fluid takes on a gel-like consistency, the surrounding cells literally become starved from lack of nutrition. The exciting news is that the proanthocyanidins contained in Proanthodyn are among the few substances yet discovered which can help strengthen capillary walls, ensuring the liquid nature of the interstitial fluid.2 Plus, proanthocyanidins help keep capillary and artery walls flexible, allowing for proper blood flow to the heart.

    Heart Smarts

    The 1990’s mark a decade of increased awareness among Americans of important health issues. Much of the discussion has revolved around protecting that precious center of life we call the heart. Simple lifestyle change is one of the most effective ways to maintain and protect the functioning of the cardiovascular system. In order to take a holistic approach to heart care, make sure you include plenty of fresh fruits and vegetables (organic, if possible) in your diet, and cut down on fatty and cholesterol-forming foods. Reduce your salt and alcohol intake to a minimum. Try to get regular, sustained aerobic exercise for at least 30 minutes three times a week. Don’t smoke – or if you do smoke, try to eat even more fresh fruits and antioxidant-rich vegetables to counter the amount of free radicals being produced in your body. Lastly, consider adding Source Naturals HEART SCIENCE to your health regimen. HEART SCIENCE, the most comprehensive formula of its kind, provides targeted protection to the entire cardiovascular system. By approaching the promotion of normal heart function on five different levels — through the inclusion of ingredients which supply energy, decrease harmful homocysteine levels, fight cholesterol build-up, help regulate electrical rhythm, and protect artery and capillary linings — HEART SCIENCE is the perfect addition to a holistic approach to heart care.

    Source Naturals HEART SCIENCE™


    The Five Tiered Approach to Heart Health
    Six tablets contain:
    Vitamins and Minerals %USRDA
    Pro-Vit A (Beta Carotene) 45,000 IU 900%
    Vit B1 (Thiamine) 50 mg 3333%
    Vit B3 (Inositol Hexanicotinate) 500 mg 2500%
    Vit B6 (Pyridoxine HCl) 25 mg 1250%
    Coenzyme B6 (Pyridoxal-5-Phosphate)
    25 mg yielding: 16.9 mg of Vit B6 845% (Total Vitamin B6 Activity) (41.9 mg) (2095%)
    Vit B12 (Cyanocobalamin) 500 mcg 8333%
    Folic Acid 800 mcg 200%
    Vit C (Magnesium Ascorbate) 1500 mg 2500%
    Vit E (d-alpha Tocopheryl Succinate) 400 IU 1333%
    Chromium (ChromeMate® †Polynicotinate-150 mcg & Chromium Picolinate††-150 mcg) 300 mcg *
    Copper (Sebacate) 750 mcg 37.5%
    Magnesium (Ascorbate, Taurinate & Oxide) 300 mg 75%
    Potassium (Citrate) 99 mg *
    Selenium (L-Selenomethionine) 200 mcg *
    Silicon (From 400 mg of Horsetail Extract) 13mg *
    * U.S. RDA not established.
    Other Ingredients and Herbs
    Coenzyme Q10 (Ubiquinone) 60 mg
    L-Carnitine (L-Tartrate) 500 mg
    Hawthorn Berry Extract 400 mg
    Proanthodyn™ (Yielding 95 mg of Proanthocyanidins from grape seed extract) 100 mg
    L-Proline 500 mg
    L-Lysine (HCl) 500 mg
    NAG™ (N-Acetyl Glucosamine) 500 mg
    Bromelain (2000 G.D.U. per gram) 1200 G.D.U.
    Taurine (Magnesium Taurinate) 500 mg
    Horsetail Extract (Yielding 31 mg of Silica) 400 mg
    Inositol (Hexanicotinate) 50 mg

    Reference:
    1. Azuma, J., Sawamura, A., & Awata, N. (1992, Jan). “Usefulness of Taurine... and its Prospective Application.” Japanese Circulation Journal, 56(1), 95-9.
    2. Blazso, G and Gabor, M. (1980). “Odema-inhibiting Effect of Procyanidin.” Acta Physiologica Academiae ScientiarumHungaricae, 56(2), 235-240.
    3. Brattstrom, E. L, Hultberg, L. B., & Hardebo, E. J. (1985, Nov.). “Folic Acid Responsive Postmenopausal Homocysteinemia.” Metabolism, (34)11, 1073-1077.
    4. Colette, C., et al., (1988). “Platelet Function in Type I Diabetes: Effects of Supplementation with Large Doses of Vitamin E.” American Journal of Clinical Nutrition, 47, 256-61.
    5. England, M. R., et al. (1992, Nov. 4). “Magnesium Administration and Dysrhythmias...A Placebo-controlled, Double-blind, Randomized Trial.” Journal of the American Medical Association, 268(17), 2395-402.
    6. Felton, G. E. (1980, Nov.). “Fibrinolytic and Antithrombotic Action of Bromelain...” Medical Hypotheses (11)6, 1123-33.
    7. Grundy, S. M. (1993, Apr.). “Oxidized LDL and Atherogenesis: Relation to Risk Factors...” Clinical Cardiology, 16 (4 Suppl.I), I3-5.
    8. Hano, O. et al. (1994, June). “Coenzyme Q10 Enhances Cardiac Functional and Metabolic Recovery and Reduces Ca2+ Overload during Postischemic Reperfusion.” American Journal of Physiology, 266(6 Pt 2), H2174-81.
    9. Heineke, et al. (1972). “Effect of Bromelain (Ananase) on Human Platelet Aggregation.” Experientia V. 23, 844-45.
    10. Hendler, S. S. (1991). The Doctors’ Vitamin and Mineral Encyclopedia. NewYork: Fireside.
    11. Jandak, et al. (1988, Dec. 15). “Reduction of Platelet Adhesiveness by Vitamin E Supplementation in Humans.” Thrombosis Research 49(4), 393-404.
    12. Jialal, I., et al. (1991, Oct. 15). “Beta-Carotene Inhibits the Oxidative Modification of Low-density Lipoprotein.” Biochimica et Biophysica Acta, 1086(1), 134-8.
    13. Jialal, I. & Fuller, C. J. (1993, Apr. 16). “Oxidized LDL and Antioxidants.” Clinical Cardiology, Vol. 16 (Suppl. I), I6-9.
    14. Jialal, I., & Grundy, S.M. (1991, Feb.). “Preservation of the Endogenous Antioxidants in Low Density Lipoprotein...” Journal of Clinical Investigation, 87(2), 597-601.
    15. Kamikawa, T., et al. (1985). “Effects of Coenzyme Q10 on Exercise Tolerance...” American Journal of Cardiology, 56, 247-251.
    16. Kosolcharoen, P., et al. (1981, Nov.). “Improved Exercise Tolerance after Administration of Carnitine.” Current Therapeutic Research, 753-764.
    17. Lawn, R. (1992, June). “Lipoprotein (a) in ...” Medicine, 12-18.
    18. Mortensen, S.A.et al. (1985). “Long-term coenzyme Q10 therapy: A major advance in the management of resistant myocardial failure.” Drugs Exp. Clin. Res., 11(8), 581-93.
    19. Nayler, W. G. (1980). “The Use of Coenzyme Q10 to Protect Ischemic Heart Muscle.” In: Yamamura Y., Folkners K., Ito Y., eds. Biomedical and Clinical Aspects of Coenzyme Q, Vol. 2, Amsterdam: Elsevier/North-Holland Biochemical Press, 409-425.
    20. Press, R.I., & Geller, J., (1990, Jan.). “The Effect of Chromium Picolinate on Serum Cholesterol and Apolipoprotein Fractions in Human Subjects.” Western Journal of Medicine, 152, 41-45.
    21. Rath, M. (1993). Eradicating Heart Disease. San Francisco: Health Now.
    22. Rossi, C. S., & Silliprandi, N. (1982, Feb.). “Effect of Carnitine on Serum HDL Cholesterol: Report of Two Cases.” Johns Hopkins Medical Journal, 150(2), 51-4.
    23. Schwarz, K. (1977, Feb. 2). “Silicon, Fibre, and Atherosclerosis.” The Lancet, 454-456.
    24. Selhub, J., et al. (1995, Feb. 2). “Association Between Plasma Homocysteine Concentrations and Extracranial Carotid-artery Stenosis.” New England Journal of Medicine, 332(5), 286-291.
    25. Somer, Elizabeth. (1992). The Essential Guide to Vitamins and Minerals. New York: Health Media of America.
    26. Stampfer, M. J., et al. (1992, Aug. 19). “A Prospective Study of Plasma Homocyst(e)ine...” Journal of the American Medical Association, 268(7), 877-881.
    27. Suadicani, P., Hein, H. O., & Gyntelberg, F. (1992, Sept.). “Serum Selenium Concentration...in a Prospective Cohort Study of 3000 Males.” Atherosclerosis, 96(1), 33-42.
    28. Thomas, C. L. (Eds.). (1985). Taber’s Cyclopedic Medical Dictionary, (15th ed.). Philadelphia: F.A. Davis Company.
    29. Tsuyusaki, T. et al. “Mechanocardiography of ischemic or hypertensive heart failure,” in Yamaura Y et al., Biomed. & Clin. Aspects of Coenzyme Q.2 Amsterdam, Elsevier/North Holland Biomedical Press, 1980, 273-88.
    30. Verlangieri, A. J., & Stevens, J. W. (1979). “L-Ascorbic Acid: Effects on Aortic Glycosaminoglycan S Incorporation...” Blood Vessels, 16(4), 177-185.
    31. Werbach, M. R. (1987). Nutritional Influences on Illness: A Sourcebook of Clinical Research. New Canaan: Keats Publishing, Inc.
    32. White, R.R., et al. (1988, Jul-Aug.). “Bioavailability of 125I Bromelain after Oral Administration to Rats.” Biopharmaceutics and Drug Disposition, 9(4), 397-403.
    33. Whitney, E. N., Hamilton, Nunnelly, E. M. (1984). Understanding Nutrition, (3rd ed.). St. Paul: West Publishing Company.
    34. Willard, Terry, Ph.D. (1992). Textbook of Advanced Herbology. Calgary, Alberta, Canada: Wild Rose College of Natural Healing.
    35. Xiang, H., Heyliger, et al. (1988, Nov.). “Effect of Myo-inositol and T3 on Myocardial Lipids and Cardiac Function in Streptozocin-induced Diabetic Rats.” Diabetes, 37(11), 1542-8.



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    TopPreviousNext

    Date: May 09, 2005 06:10 PM
    Author: Darrell Miller (dm@vitanetonline.com)

    It's in the Blood

    Natural alternatives abound for managing cholesterol levels, backed by a growing body of research ©VR By Paul Bubny

    The National Cholesterol Education Program (NCEP) last July lowered the threshold for considering the use of statin drugs—a move which some say was motivated more by profits than scientific evidence. For example, the Center for Science in the Public Interest pointed out that eight of the nine authors behind the new recommendations had financial ties to statin manufacturers, which stand to reap billions of dollars more from a category that grossed $14 billion in the U.S. last year. And though the Food and Drug Administration (FDA) in January decided against authorizing over-the-counter (OTC) sales of statin drugs, drug companies would still like to see this happen.

    “The medical establishment’s pushing of these drugs to becoming the number one category of prescribed drugs in the world has led them to keep lowering the total cholesterol number that triggers the drug recommendation,” said Neil E. Levin, C.C.N., D.A.N.L.A., nutrition educator, product formulator, and “Truth Advocate” for NOW Foods (Bloomingdale, IL), which produces a number of supplements for addressing cholesterol. “This is despite the lack of evidence that total cholesterol means much as regards cardiovascular risks.

    “Other tests are much more important in terms of predicting risks, including CRP (C-reactive protein), the balance of different cholesterol fractions, and homocysteine,” he continued. “Add adult-onset diabetes to the risk factors for cardiovascular disease (CVD).”

    At the same time, the allegation that enormous sales potential lay behind the lower threshold for prescribing statin drugs illustrates how widespread the problem of hypercholesterolemia (elevated total cholesterol) is. More than 100 million Americans have elevated cholesterol (total cholesterol values of 200 mg/dl and higher), and of these, more than a third have high cholesterol (levels of 240 mg/dl and higher), according to the American Heart Association. Those numbers have unfavorable implications for the incidence of CVD, as high cholesterol is considered a risk factor for coronary heart disease and stroke.

    While statin drugs haven’t garnered the same degree of negative publicity that COX-2 inhibitors have suffered lately, safety concerns have arisen nonetheless. For one thing, these drugs lower the liver’s production of coenzyme Q10 (coQ10) along with its production of cholesterol. “CoQ10 is related to energy production and immune functions, is an antioxidant, and [is] an important cardiovascular nutrient,” Levin said. “It is not good to lower one’s coQ10 levels by half!”

    Moreover, said Levin, statins increase the tendency of muscle tissues to break down. “Combined with inactivity or certain drugs, this can stimulate muscle wasting,” he said. “Muscle is where a good deal of calories are burned, so a loss of muscle could affect mobility and energy production, potentially adding to obesity problems. These muscle changes occurred in patients and persisted for years after treatment was discontinued, as shown by muscle biopsies, even if no obvious muscle problems were observed by the patients.”

    And the last word on the subject may not have been spoken. Predicted Dr. Frank King, Jr. president of King Bio Natural Medicine (Asheville, NC), “Once the appropriate studies are finished, these drugs, along with hypertensives, will hit the fan bigger than the COX-2 inhibitors.”

    Also looking toward the future, Levin said that of the 20 million Americans who will be “targeted” for statin drug prescriptions under the new NCEP guidelines, “Some of these will want to try natural methods first. Others will rebel at the side effects of the drugs and experiment with alternative products.”

    King and Levin both saw opportunity for natural products in the fallout from drug safety concerns, with King projecting that sales of his company’s cholesterol-related homeopathic remedies will double in 2005. “The reports of deaths from drugs will always overshadow the trumped-up studies and news reports blasting dietary supplements,” said Levin. “Vioxx knocked vitamin E off the media’s radar screens pretty rapidly, though we still see ignorant reporters citing that [Johns Hopkins] vitamin E analysis as if it were true. But the comparable safety of supplements means that open-minded people will want to at least try natural therapies before signing in to a lifetime of drug therapies. Meanwhile, the studies on natural products will continue to build our credibility.”

    Those studies keep coming in, with at least four major findings published in the past few months, plus a heart-health claim on walnuts authorized by FDA. They join a raft of earlier findings that link natural products—branded and otherwise—to healthy cholesterol levels.

    "Blur of Products"

    With so many natural alternatives to cholesterol drugs available, it can be hard to keep track. “As with any other category, the blur of products as they cascade over several shelves means that the retailer needs to have a good sense of what works and what they want to recommend to their customers,” Levin said. “Really, each person needs a protocol that would include antioxidants, fiber, vitamins, herbs, and oils. The pre-mixed cholesterol support formulas are a good starting place.”

    To help retailers get a sense of “what works,” here is an alphabetical discussion of several nutrients that have demonstrated benefits in serum cholesterol levels. They include the following:

    Barley may help lower cholesterol, according to a report in the American Journal of Clinical Nutrition (2004, vol.80, no.5: 1185-1193). Twenty-five adults with mild hypercholesterolemia consumed a controlled diet low in total fat, saturated fat, and cholesterol for 19 weeks. They then added whole-grain products containing barley to their diets that contained low (0 g), medium (3 g), or high (6 g) amount of beta-glucan per day for five weeks. Total cholesterol was reduced by 4 percent 9 percent, and 10 percent, respectively. The diet with the highest amount of beta-glucan led to a decrease in LDL cholesterol of 17 percent.

    Chromium. There’s evidence, Levin said, that chromium in doses of 500 mg a day may decrease levels of low-density lipoprotein (LDL, the so-called “bad” cholesterol) and total cholesterol while raising levels of high-density lipoprotein (HDL, or “good” cholesterol). At the annual meeting of the American College of Nutrition last October, a poster presentation on the safety of Benicia, CA-based InterHealth Nutraceuticals’ ChromeMate niacin-bound chromium won first prize; among other things, the presentation cited chromium’s role in maintaining healthy blood lipid levels.

    Fatty Acids. The latest in a long line of studies demonstrating the benefits of fatty acids in heart health is a study published in The International Journal of Clinical Pharmacology and Therapeutics in December 2004. It showed that docosahexaenoic acid (DHA), an omega-3 fatty acid, can restore normal blood vessel function in children with inherited high cholesterol. The study, which used Martek DHA produced from microalgae, concluded that restoration of normal blood vessel function has the “potential for preventing the progression of early coronary heart disease in high-risk children.”

    “The evidence continues to accumulate on the cardiovascular benefits of DHA for people of all ages,” said Henry “Pete” Linsert, Jr., chairman and CEO of Martek Biosciences, an ingredient supplier based in Columbia, MD. “This study clearly indicates that DHA played an important role in healthy blood vessel function in the children in this study.”

    On the Omega-Research.com Website maintained by fish oil manufacturer Nordic Naturals (Watsonville, CA) can be found summaries of several earlier studies linking omega-3 fatty acids to maintaining healthy blood lipid levels, as well as related benefits such as elasticity of the arteries. In a 2003 study published in the American Journal of Clinical Nutrition, it was found that women receiving a mixture of 4 g eicosapentaenoic acid (EPA) and DHA along with 2 g of gamma-linolenic acid (GLA) had lower levels of LDL cholesterol after 28 days compared to those who received either the EPA/DHA supplements without DHA, EPA/DHA with a smaller dose of GLA, or GLA alone.

    Flax is another source of omega-3s, and Arkopharma/Health From The Sun (Bedford, MA) offers FiProFLAX in a variety of forms. Marketing director Hugues P. Mas said the flax is “QAI [Quality Assurance International] certified organic and guaranteed GMO [genetically modified organism]-free.” On its Website, the company offers a cholesterol quiz geared to consumers, discussing the importance of omega-3s as well as other nutrients.

    Garlic. Adding to an already considerable body of research demonstrating that garlic can lower total cholesterol, LDL cholesterol, and triglycerides while increasing HDL cholesterol, researchers at UCLA in 2003 reported that Kyolic aged garlic extract reduced or inhibited plaque formation in the arteries of 19 cardiac patients taking statin drugs.

    Lead researcher Matthew Budoff, Ph.D. commented at the time that the study “suggests that aged garlic extract may be a useful and beneficial dietary addition for the people who have high cardiovascular risk or who have undergone heart surgery.” Budoff has since presented several trade show seminars sponsored by Los Angeles-based Wakunaga of America, the makers of Kyolic.

    Guggul. In use for centuries as a component of Ayurvedic medicine, guggul—a gummy resin tapped from the Commiphora mukul tree, which is native to India—has been studied since the early 1960s for its hypolidemic (blood-lipid lowering) properties. Sabinsa Corp. (Piscataway, NJ), an ingredient supplier which produces a standardized extract under the brand name Gugulipid, says the studies on guggul indicate that its hypolipidemic activity can be attributed to more than one mechanism of action.

    Among the possible mechanisms are: inhibition of cholesterol biosynthesis, enhancing the rate of excretion of cholesterol, promoting rapid degradation of cholesterol, thyroid stimulation, alteration of biogenic amines, and “high affinity binding and anion exchange.”

    Homeopathy. “Homeopathy activates the body’s own control system to work properly,” said King. “This is the safest and most curative approach to take.

    “Forcing the body into biochemical change even naturally doesn’t actually have the curative action of homeopathy,” King continued. “Homeopathy can even correct the genetic predispositions to disease we may have inherited from as deep as a thousand years into our family chain.” King Bio makes Artery/Cholesterol/BP, a homeopathic formula intended to help tone heart muscles and blood vessels.

    Low glycemic index foods. In a study published in the February issue of the American Journal of Clinical Nutrition, researchers found that high glycemic load is negatively correlated to serum levels of HDL cholesterol. Assessing the relationship between blood levels of lipids and diet in a test population of 32 healthy males and females ages 11 to 25, the researchers found that glycemic load accounted for 21.1 percent of the variation in HDL cholesterol. They concluded that glycemic load appears to be an important independent predictor of HDL cholesterol in youth and noted that dietary restrictions without attention to glycemic load could unfavorably influence blood lipids.

    Medicinal Mushrooms. Although its product SX-Fraction is intended primarily to address high blood sugar, Maitake Products, Inc. (MPI, Ridgefield Park, NJ) found in a clinical study that LDL cholesterol in diabetic patients declined modestly (from 142 mg/dl to 133 mg/dl) over a two-month period. Those taking SX-Fraction also lost about 7 lbs. in the same time period.

    “The more impressive lowering of cholesterol, however, comes from the dietary fiber that is found in all medicinal mushrooms,” said Ellen Shnidman, manager of scientific affairs at MPI. She cited animal studies which documented the cholesterol-lowering properties of four different mushrooms: maitake, shiitake, agaricus, and enokitake.

    For example, a study reported in the September 1996 issue of Alternative Therapies showed “a 44 percent reduction in total cholesterol in rats consuming maitake mushroom in their diet,” said Shnidman. “This cholesterol reduction is accompanied by weight loss, relative to rats eating a similar high-choelsterol diet without mushrooms. Apparently, cholesterol is excreted by the rats in sufficient quantity to aid in weight loss.”

    Oat bran. A 2004 consumer study conducted by the Natural Marketing Institute (NMI, Harleysville, PA) for Nurture, Inc. (Devon, PA), which produces the ingredient OatVantage, found that 63 percent of consumers managing their cholesterol levels prefer oat-based ingredients.

    Oat bran is the subject of a health claim authorized by FDA in 1999, and NMI research found that 69 percent of respondents preferred the FDA-permitted health claim, “Helps Lower Cholesterol,” over the model structure-function claim, “Helps Maintain Healthy Cholesterol Levels.” “This is significant for food, beverage, and dietary supplement manufacturers who want to increase sales by using a more consumer-desired claim on the product label,” said Griff Parker, Nurture CEO.

    Plant sterols. Also the subject of an FDA-approved claim for heart health, plant sterols (structurally similar to cholesterol in humans) can block the absorption of cholesterol, according to a number of studies. In an “Ask the Doctor” publication (available online at www.atdonline.org), Decker Weiss, N.M.D. noted that sterols enter the same receptor sites that cholesterol enters on its way to the bloodstream. “The cholesterol, being blocked from absorption, remains in our intestines where it is eventually excreted,” Weiss wrote. General Mills has just introduced Yoplait Healthy Heart, a yogurt high in plant sterols.

    Policosanol. A mixture of fatty alcohols derived from sugar cane or beeswax, policosanol has been favorably compared in clinical studies to several types of prescription drugs for managing cholesterol. On its own, policosanol was found in a 1999 study to reduce LDL cholesterol while raising levels of HDL cholesterol.

    Probiotics. “Several studies have indicated that consumption of certain cultured dairy products resulted in reduction of serum cholesterol, as well as triglycerides,” wrote Dr. S.K. Dash, president of probiotic manufacturer UAS Laboratories (Eden Prairie, MN), in his Consumer Guide to Probiotics. Among other studies, Dash cited two controlled clinical studies from the VA Medical Center at the University of Kentucky.

    “In the first study, fermented milk containing [Lactobacillus] acidophilus was accompanied by a 2.4 percent reduction of serum cholesterol concentration,” he wrote. “In the second study, a different L. acidophilus strain reduced serum cholesterol concentration by 3.2 percent. Since every 1 percent reduction in serum cholesterol concentration is associated with an estimated 2 to 3 percent reduction in risk for coronary heart disease [CHD], regular intake of fermented milk containing an appropriate strain of L. acidophilus has the potential of reducing risk for [CHD] by 6 to 10 percent.”

    Dash said his company’s DDS Probiotics contain DDS-1 L. acidophilus, “which has been researched and demonstrated to show cholesterol-lowering effect.”

    Psyllium. “Internal cleansing is very important” in maintaining healthy cholesterol levels, “especially if you do it with a lot of fiber,” said Sunil Kohli, vice president of Chino, CA-based Health Plus, Inc. The cholesterol-managing ability of fiber in general and psyllium in particular is “very well-established,” he said.

    However, Kohli said, “It will probably do you no good if it’s random. It should be done on a regular basis, and it should be supervised. Consulting the doctor or pharmacist is important.”

    Soy. The protein in soy “has evidence of lowering total cholesterol and LDL cholesterol, based on reviews of studies using over 20 g of soy protein per day,” said Levin. “Soy isoflavones are considered only partly responsible for this effect.”

    Sytrinol. A patented proprietary formula derived from natural citrus and palm fruit extracts and containing citrus polymethoxylated flavones and palm tocotrienols, Sytrinol has been shown in clinical trials to improve total cholesterol, LDL cholesterol, and triglycerides by up to 30 percent, 27 percent, and 33 percent, respectively. Having just wrapped up Phase III of a long-term trial of Sytrinol, Chicago-based SourceOne Global Partners, which owns the exclusive worldwide license for intellectual property associated with the ingredient, is commencing a study that combines Sytrinol with plant sterols.

    Tocotrienols. On its Website discussing the science and benefits of tocotrienols (www.tocotrienol.org), ingredient supplier Carotech Inc. (Edison, NJ) identifies several benefits for blood lipid levels. Tocotrienols, according to the Website, have been shown to “inhibit cholesterol production in the liver, thereby lowering total blood cholesterol;” “[suppress] hepatic HMG-CoA reductase activity [and result in] the lowering of LDL cholesterol levels;” and “inhibit cholesterogenesis by suppressing HMG-CoA reductase.”

    New Weapons

    There are also nutrients that are emerging as potential weapons in the fight against cholesterol. Levin cited rice bran oil, resveratrol, pantethine, l-carnitine, and niacin as showing promise.

    With all of this, Levin said, it’s important for retailers to remember that “they are not allowed to discuss diseases and remedies unless there is an approved FDA health claim allowed on the label, as with soy protein and plant sterols. What is allowed are structure-function claims such as ‘cholesterol support,’ ‘promoting normal, healthy circulation,’ ‘homocysteine regulators,’ etc.”

    Supplementation is only one tool for managing cholesterol levels, manufacturers pointed out. “Besides nutrition, lifestyle is a key to controlling cholesterol,” Levin said. “Eating a variety of antioxidant-rich foods will prevent the liver from churning out cholesterol as a ‘cheap’ antioxidant. The body uses oxidized cholesterol to patch leaky and damaged blood vessels, so the ability to build healthy collagen is a must, using nutrients like vitamin C, Pycnogenol, rutin, hyaluronic acid, and MSM.

    “Don’t forget exercise and stress reduction,” he added. “Stress results in high cortisol levels—usually accompanied by poor blood lipid levels—and a lack of good sleep to produce unhealthy people.” VR

    Vitamin Retailer Magazine, Inc., 431 Cranbury Road, East Brunswick, NJ 08816 //www.oprmagazine.com/

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