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Search Term: " Glucosamine "
Soothing relief for achy muscles and joints   
Date:
October 26, 2022 12:33 PM
Feeling sore after a workout? You're not alone. Aching muscles and joints are common, especially if you're new to exercise or you've had a particularly intense session. Thankfully, there's a natural way to soothe your soreness and ease your discomfort. NOW® Solutions Joint & Muscle Cream is specially formulated to provide relief for the skin surrounding active joints and muscles. Keep reading to learn more about this product and how it can help you feel your best. How NOW® Solutions Joint & Muscle Cream Works This product contains Glucosamine, a compound normally found in the articular cartilage of joints. Glucosamine is known for its ability to support healthy joint function and ease occasional discomfort associated with exercise or overexertion. The cream also includes boswellia, capsaicin, and natural methyl salicylate. These three active ingredients are combined for their skin care properties and for conditioning the areas around joints and muscles. Boswellia is an Indian herb that has been used for centuries to support healthy inflammation response. Capsaicin is derived from chili peppers and is known for its ability to temporarily relieve minor muscle pain. Methyl salicylate is a naturally occurring organic compound that gives wintergreen its characteristic fragrance and flavor. It's also used topically for its soothing properties. When applied to the skin, NOW® Solutions Joint & Muscle Cream penetrates deeply to deliver its moisture-attracting capabilities directly where you need it most. This product is fast-absorbing, non-greasy, and non-staining, making it ideal for use before or after exercise. It's also free of parabens, propylene glycol, synthetic fragrances, dyes, and phthalates. Plus, it's dermatologist tested and safe for all skin types. If you're looking for a natural way to relieve occasional muscle pain and discomfort, try NOW® Solutions Joint & Muscle Cream. This product contains Glucosamine, boswellia, capsaicin, and natural methyl salicylate—all of which are known for their ability to soothe soreness and ease discomfort. The cream is fast-absorbing, non-greasy, and non-staining, making it easy to apply before or after exercise. It's also free of parabens, propylene glycol, synthetic fragrances, dyes, phthalates, making it a good choice for those with sensitive skin. Plus, it's dermatologist tested and safe for all skin types. Give NOW® Solutions Joint & Muscle Cream a try today!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6530) Soothe Your Joints with Glucosamine, MSM & Arnica Liposomal Lotion 
Date:
October 20, 2022 02:03 PM
If you're struggling with sore, aching joints, you're not alone. In fact, according to the CDC, 1 in 2 adults aged 18 and over have some form of joint pain. While there are various treatments available, many come with undesirable side effects. Fortunately, there's a new joint lotion on the market that's getting rave reviews from users—NOW Solutions Glucosamine, MSM & Arnica Liposomal Lotion. What is NOW Solutions Glucosamine, MSM & Arnica Liposomal Lotion? NOW Solutions Glucosamine, MSM & Arnica Liposomal Lotion is a soothing lotion specifically formulated for use on joint areas. This unique blend of ingredients combines Glucosamine, a normal joint and cartilage component with MSM, a source of organic sulfur. Sulfur is an element known to be a normal component of connective tissue structures. Arnica is well known for its traditional uses. NOW Solutions uses liposome technology for enhanced absorption. Liposomes are very similar to the different layers of the skin barrier and compatible with cell membranes. Due to their mimicking ability, the liposome can more easily moisturize the skin’s natural barrier layers, and allow the ingredients to function more effectively. How Does NOW Solutions Glucosamine, MSM & Arnica Liposomal Lotion Work? When applied topically, NOW Solutions Glucosamine, MSM & Arnica Liposomal Lotion helps to temporarily relieve minor aches and pains associated with arthritis, simple backaches, muscle strains and sprains. The lotion also helps to increase circulation and reduce inflammation. Who Can Benefit from Using NOW Solutions Glucosamine, MSM & Arnica Liposomal Lotion? NOW Solutions Glucosamine, MSM & Arnica Liposomal Lotion is ideal for anyone who suffers from joint pain or inflammation. The lotion can be used as needed on sore joints or muscles and is safe for daily use. The non-greasy formula absorbs quickly and won't leave your skin feeling oily or sticky. It's also Paraben-free and has a refreshing menthol scent. If you're struggling with sore joints or inflamed muscles, give NOW Solutions Glucosamine, MSM & Arnica Liposomal Lotion a try. This unique lotion contains ingredients that are known to help reduce pain and inflammation while increasing circulation. The non-greasy formula absorbs quickly into the skin leaving you feeling refreshed and cool. It's also Paraben-free and has a refreshing menthol scent that makes it enjoyable to use. Give NOW Solutions Glucosamine >MSM & Arnica Liposomal Lotion a try today! You'll be glad you did!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6510) Safe and Effective Joint Pain Relief: Natural Supplements That Work
Date:
July 21, 2022 10:41 AM
Do you suffer from joint pain? If so, you're not alone. In fact, according to the Arthritis Foundation, over 50 million adults in the United States are affected by some form of arthritis. And if that's not bad enough, it's estimated that by 2030, that number will grow to 67 million! The good news is that there are safe and effective ways to relieve joint pain without resorting to over-the-counter drugs. We'll discuss natural supplements like Glucosamine, chondroitin sulfate, and MSM that have been shown to help rebuild cartilage and reduce inflammation. What is joint pain and what are the most common causes? joint pain is a common symptom that can be caused by a variety of conditions. The most common causes include arthritis, bursitis, and tendinitis. Arthritis is a general term used to describe inflammation of the joints. There are many different types of arthritis, but the most common are osteoarthritis and rheumatoid arthritis. Bursitis is the inflammation of the small sacs of fluid that cushion the joint, while tendinitis is the inflammation of the tendons that attach muscle to bone. Joint pain can also be caused by injuries, such as sprains and fractures. In some cases, the exact cause of joint pain cannot be determined. Treatment for joint pain depends on the underlying cause. How can over-the-counter drugs be harmful to your health? The wide availability of over-the-counter (OTC) drugs such as acetaminophen and ibuprofen can be a godsend when we are feeling pain or discomfort. However, it is important to remember that these drugs are potent medications that can also be harmful to our health if we take them inappropriately. Acetaminophen and ibuprofen are both nonsteroidal anti-inflammatory drugs (NSAIDs). NSAIDs work by reducing inflammation, but they can also have adverse effects on the gastrointestinal tract, kidneys, and liver. In addition, NSAIDs can interact with other medications that we may be taking, so it is important to speak to a healthcare professional before taking them. Although OTC drugs can be helpful when used as directed, it is important to be aware of the potential risks involved in taking them. What are some natural supplements that have been shown to help relieve joint pain safely and effectively? While there are a number of different supplements that have been traditionally used to help relieve joint pain, not all of them have been proven to be effective. However, there are a few natural supplements that have been shown to be safe and effective for this purpose. Glucosamine is a supplement that has been shown to help rebuild cartilage and relieve pain in osteoarthritis sufferers. Another promising supplement is chondroitin and msm, which helps to reduce inflammation and ease the symptoms of joint pain. Finally, fish oil supplements have also been shown to be effective in reducing inflammation and relieving joint pain. Turmeric, Boswellia, and CBD also reduce inflammation. When used together, these natural supplements can provide significant relief from joint pain. How do Glucosamine, chondroitin sulfate, and MSM work to reduce inflammation and rebuild cartilage tissue? Glucosamine, chondroitin sulfate, and MSM are all natural compounds that have been shown to be effective in reducing inflammation and rebuilding cartilage tissue. Glucosamine is an amino sugar that is produced naturally by the body. It is a building block of cartilage, and it has been shown to stimulate the production of new cartilage. Chondroitin sulfate is a complex carbohydrate that is also found naturally in the body. It helps to keep cartilage healthy by protecting it from wear and tear. MSM (methylsulfonylmethane) is a sulfur-containing compound that is found naturally in some foods. It has anti-inflammatory properties and has been shown to promote the repair of damaged cartilage. Together, these three compounds can help to reduce inflammation and improve the health of cartilage tissue. How long should you take these supplements for maximum benefit, and when should you stop taking them if you don't experience results within a certain time frame? Many people take supplements in order to improve their health or address a specific health concern. But how long should you take them for? In general, most supplements should be taken for at least 6 to 8 weeks in order to see maximum benefit. However, some people may not see results until 12 weeks of supplementation. Of course, if you're working with a healthcare professional, they can help you determine when to start and stop taking supplements. But in general, 6 to 8 weeks is a good rule of thumb. Don't be afraid to add Turmeric or Boswellia to the mix. These herbs can enhance the effectiveness of the Glucosamine, chondroitin, and MSM. Taking a natural supplement like Glucosamine, chondroitin sulfate, and MSM can be an effective way to reduce inflammation and rebuild cartilage tissue safely and effectively. These supplements have been shown to be safe and effective for this purpose. When taken together, they can provide significant relief from joint pain. It is important to speak to a healthcare professional before taking these supplements if you are taking other medications, as there is potential for adverse effects. Be sure to take 1500mg of each in divided dosages though out each day for at least 6 to 8 weeks in order to see maximum benefit.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6419) Understanding Inflammation and How It Affects Your Skin
Date:
April 08, 2017 03:44 PM
Inflammation is a problem that is linked to many diseases, and it can also adversely affect your skin. It's linked to many skin conditions and can also be responsible for signs of aging. However, there are many natural ingredients out there that combat inflammation and they are in many skin products. Ingredients like Gotu Kola, growth factors, ergothioneine, glucosamine, Omega 6, peptides, and vitamin C are very effective in fighting inflammation. Read this article for more details into these ingredients and what else you can do to fight inflammation of the skin. Key Takeaways:
"chronic inflammation appears strongly linked to many preventable and treatable skin diseases and conditions such as visible skin aging." Read more: https://www.truthinaging.com/review/understanding-inflammation-and-skin-care
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4378) What Makes a Good Joint Complex or Formula?
Date:
June 29, 2011 11:44 AM
Glucosamine/Chondroitin/MSMJoint pain is a common medical condition that afflicts billions of people worldwide. It is brought on by many different factors, though most of the cases have been tied to arthritis. The joints are especially susceptible to inflammation in old age partly due to the fact that cartilage health becomes impaired as we age. The good news is that certain organic compounds replenish the cartilage content of joints. Medications and remedies formulated to alleviate joint pain have been extensively studied in the past few decades. Analgesics remain the mainstay of treatment for arthritis to this day, but alternative medicine has also made advances. Proponents of nutritional supplements believe that a good joint formula does not only provide relief from pain but also supplies the proteins necessary for joint health. Glucosamine Joint cartilage comprises a group of complex carbohydrates called polysaccharides or oligosaccharides that are attached to proteins. In a process called glycosylation, enzymes add long unbranched chains of carbohydrates to core proteins and form proteoglycans, which nourish the extracellular matrix found in cartilages. In the case of osteoarthritis, the proteoglycan content of joints dwindle with age. Glucosamine is a precursor to polysaccharides and oligosaccharides. In particular, it is utilized by enzymes to form glycosaminoglycans, which are in turn added to proteoglycans. As a treatment for joint pain, it comes in the form of Glucosamine sulfate and Glucosamine hydrochloride. It is one of the most promising of all complementary therapies for arthritis as studies have reported positive results. Chondroitin Therapeutic remedies that contain Glucosamine often come with chondroitin. The sulfated form of chondroitin is a major constituent of proteoglycans, and as such it is generally found in large amounts in joint cartilage in humans. For decades, chondroitin has been used as a therapeutic remedy for arthritis in conjunction with Glucosamine as they are believed to enhance the efficacy of each other. Proponents believe that chondroitin and Glucosamine supply the body with healthy quantities of glycosaminoglycans for use by enzymes in the synthesis of proteoglycans. There is consensus in the scientific community that its long term use for the sole purpose of treating osteoarthritis is safe. In addition, recent studies and clinical trials in the past few years have been very encouraging. MSM Methylsulfonylmethane, often abbreviated as MSM, is a compound listen as an ingredient in joint formulas. Nutraceutical experts believe that the best joint formula currently available contains all three: Glucosamine, chondroitin, and methylsulfonylmethane. While Glucosamine and chondroitin provides nutrition for cartilage tissue, MSM counteracts inflammatory mediators that cause joint pain. Alternative remedies have been the subject of most studies on arthritis in recent years. While analgesics remain commonly used, dietary supplements are becoming increasingly popular among people suffering from joint pain. Glucosamine, chondroitin, and MSM are the most studied of all supplements formulated for joint pain, the reason why health care providers recommend them first. Grab yourself a joint formula complex and feel the difference!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2352) Glucosamine and Joing Pain
Date:
April 05, 2010 04:34 PM
A decline in the amount of Glucosamine production occurs along with the normal aging process. This compound is involved in the natural cushioning of the joints, which means that damage and pain can result from a lack of Glucosamine. When the natural cushion is gone, the bone and cartilage may rest against each other, which in turn causes deterioration. Not only can this occur in the joints, but it can also occur in the spinal column.
Glucosamine sulfate has proven to be an effective treatment for osteoarthritis. In fact, some have found that this treatment works better than conventional therapies. This is because it does more than just mask the pain. Rather, it actually aids in rebuilding and stimulating joint repair. Also, Glucosamine Scientific evidence shows that Glucosamine metabolism is altered when osteoarthritis is present within the body. It has been found that Glucosamine supplements provide an effective treatment for this condition. Studies, up to this point, have found substantial improvement in those individuals who are treated with Glucosamine. There is little risk, if any, involved in the use of Glucosamine for the treatment of osteoarthritis. Studies have shown that this compound is very safe and does not possess any known precautions or risks. One study even determined that Glucosamine sulfate has the ability to help stimulate the defense mechanisms that are present within the stomach lining. Pain and anti-inflammatory medications, on the other hand, often cause stomach problems such as ulcers.
Glucosamine sulfate has been shown to be an essential part in treating osteoarthritis. Scientific results showed significant improvement in swelling, pain, and degeneration of joints with the use of Glucosamine sulfate. Not only is this compound important for reducing the symptoms that are involved with osteoarthritis, but the supplement has been found to actually reverse the degenerative process and induce healing. This compound should be considered to be a form of treatment for osteoarthritis.
It should be noted that when taking this, or any other supplement, one should consult their health care provider before beginning any type of supplementation. Glucosamine may not be recommended in some situations. Do not take Glucosamine without first talking to your doctor if you are pregnant or could become pregnant. Similarly, be sure to consult your doctor first if you are breast feeding a baby. For more information on the many beneficial effects provided by Glucosamine, please feel free to contact a representative from your local health food store.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2135) Glucosamine Sulfate
Date:
October 02, 2008 09:36 AM
Cartilage has several roles to play in your body, an example of which is to form curved body parts that would otherwise be unsupported, such as the external contours of your ears or a large part of your nose. Without cartilage you ears and nose would flop around a lot, and it is also contained in the spine, to prevent your discs from grinding against each other. However, the part that we are interested in is as a shock absorber between the bones of your joints. It allows bones to slide over one another without damage, either through friction or shock, and is also nature’s shock absorber, helping to support your weight while you are active. Thus, your cartilage protects from impact damage when you are running or jumping down from a height. This type of cartilage, known as articular cartilage, is bathed in a lubricating fluid known as synovial fluid, which introduces its own problems when your cartilage becomes damaged. This damage can occur in several ways: as the result of a fall, for example, or direct contact with the joint when playing a physical contact sport such as football or soccer. It can also become damaged through wear and tear over a period of time, such with long distance runners or soccer players (again), and is also associated with age. Many years of continual use, especially amongst those with active rather than sedentary occupations, eventually lead to wear and damage. Problems with the joint structure itself, known as osteoarthritis, can also damage the cartilage, as can being overweight for a lengthy period. You can also experience cartilage damage if you are bedridden or other wise immobile for long periods, because the cartilage needs regular movement to function correctly. This is connected with the blood supply, which will be discussed shortly. Cartilage is constructed of cells known as chondrocytes that generate a fibrous matrix known as collagen, a mixture of amino acids known as elastin that allows the cartilage to return to its original shape after deformation, and non-collagenous matrix tissue containing proteins, water and proteoglycans that contain sulfated glycosaminoglycan chains. That last mixture is often referred to as ‘ground substance.’ One of the problems with cartilage is its lack of a direct blood supply, and it relies on the compression and decompression of the articular cartilage, or on the flexing of elastic cartilage, to create a pumping action that drives blood to the chondrocytes. This is why inactivity can cause cartilage damage, due to a lack of blood supply, and why it is repaired more slowly than other body components. Once an injury or wear and tear damages a joint, the body’s natural defense, the immune system, is activated, and the major part of that involved in cartilage damage is the inflammatory response. The joint becomes inflamed, the quantity of synovial fluid is increased to provide more protection and swells the joint, and enzymes (hyaluronidase) are produced which, although part of the natural defense system, actually degrade the synovial fluid and the cartilage. This increases the amount of inflammation and the process becomes self-perpetuating, leading to the condition known as degenerative joint disease (DJD) because the body is unable to produce enough Glucosamine to generate the proteoglycan needed for repair. This is where Glucosamine sulfate enters the scene. Glucosamine is a precursor for glycosaminoglycans (GAG), which as mentioned as above are components of proteoglycans in the cartilage matrix ground tissue. It has been shown to stimulate the biosynthesis of proteoglycan, and analysis has shown its presence within articular cartilage after administering it orally to patients with cartilage disease. It therefore makes its way to the right place. Glucosamine is administered in the form of Glucosamine sulfate, the highly electrically charged sulfate groups believed to aid in the compression properties of cartilage. It is rapidly absorbed into the bloodstream, although only about a quarter of the oral dose is eventually available to the body, and high concentrations accumulate in the liver, kidneys and in articular cartilage where it is used in the biosynthesis of GAG. When in solution, Glucosamine sulfate separates into ions: sulfate and Glucosamine. Glucosamine ions are involved in the synthesis of GAG, that then combine with proteins to form proteoglycans, a component of the non-collagenous matrix of the cartilage. Although Glucosamine is the major active component, there is evidence that the sulfate group contributes the stability of the matrix of the connective tissue since the uptake of sulfate ions increases with the amount of Glucosamine sulfate used. Another consideration here is that sulfate is an important part of proteoglycans, and Glucosamine sulfate promotes not only the synthesis of glycosaminoglycans, but also of proteoglycans in general. Glucosamine is also active in regenerating the lubricating properties of the synovial fluid, and in hindering the activity of hyaluronidase, the enzyme that breaks down the hyaluronic acid in the synovial fluid.
Some people find that Glucosamine, taken either alone or in conjunction with chondroitin sulfate and/or methyl sulfonyl methane (MSM), is more effective than the non-steroidal anti-inflammatory drugs (NSAIDs) used to reduce inflammation (e.g. Aspirin and Ibuprofen) and without the side effects of these substances. MSM contains dietary sulfur, which is necessary for cell structure and healthy cell repair. Methyl sulfone methane is know to be beneficial for painful conditions such as arthritis, and also improves the blood circulation. It might also play a part in helping Glucosamine sulfate get to the site of the cartilage damage.
Glucosamine is a large molecule, however, and finds it difficult to make its way to the area around the joint due to the lack of a direct blood supply. It is therefore taken in relatively large doses to ensure that sufficient amounts get to where it is needed. Many people insist that Glucosamine sulfate is very effective in reducing, or even eliminating, their pain, and it is finding increasing popularity in the treatment of arthritis and other conditions involving cartilage damage.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1907) Support Healthy Joint Function With Discount Vitamins
Date:
November 22, 2007 11:05 AM
The joints are very important to your mobility and it is essential that you support health joint function with discount vitamins. The reason for discounted vitamins is that there is no need for you to pay more than you have to, and good healthy bones and joints need a good supply of several vitamins, minerals and other substances to remain healthy throughout your lifetime. Vitamins C and D, and calcium and magnesium are the more common supplements that help to promote joint health, but Glucosamine, chondroitin and gelatine also play a large part. Although the strength of the bone is important, it is disorders of the connective tissue that are mostly responsible for joint problems. Connective tissue holds the joint together and prevents excessive friction between bones. Arthritis in both its forms – osteoarthritis and rheumatoid arthritis – is characterized by a reduction in the cartilage tissue that provides a lining between the bones that make up the joint. As the cartilage becomes worn or its structure destroyed, the bones are exposed to each other and this causes the frictional damage that is osteoarthritis. With rheumatoid arthritis, on the other hand, the connective tissue and cartilage are attacked by the body’s immune system, causing inflammation. The reason for this is still unknown, but the inflammation leads to swelling of the joint and severe pain. Both of these conditions can be helped by the use of Glucosamine, a natural substance produced by the body to form cartilage and stimulate the formation of connective tissue. Normally taken in the form of the sulfate, Glucosamine reduces arthritic pain, and over time can start to rebuild the lost cartilage. It is best taken in conjunction with chondroitin sulfate which is a substance also contained in cartilage and connective tissue. A discount vitamin supplement containing Glucosamine and chondroitin can help to avoid these conditions from occurring. Rheumatoid arthritis also responds well to anti-inflammatories and antioxidants. Much of the damage to the joint tissues can be caused by the action of free radicals that are aggressively destructive molecules created by the effects of pollution such as smoking, pesticides, heavy metals, alcohol and they are also produced by many of the processes occurring inside our bodies. The immune system itself creates free radicals to use as a weapon against invaders. A free radical is a molecule that has lost an electron, especially an oxygenated molecule. The objective of such a molecule is to get back its electron, and it will do that by oxidizing any molecules it comes across: oxidation is the removal of an electron from a substance. Oxidation can destroy cell molecules which is why the aging process occurs through the destruction of body cells through the effect of oxidation by free radicals. They can also destroy the synovial fluid that lubricates the joints. The molecules that can prevent this are caused antioxidants, and include some of the well known vitamins such as A, C and E, and also other substances such as Coenzyme Q10, fatty acids such as those in Omega 3 fish oils, beta carotene and the minerals zinc and copper are also effective at reducing the inflammation cause by free radical oxidation. These vitamins and minerals will not reduce the pain in your joints, but will relieve other symptoms such as the inflammation, and help the joint to recover. Vitamin D is another that can help to cause arthritis and joint problems if you are deficient in it. Vitamin D deficiency is not uncommon, especially in those who live in northern climates where they do not get much sunlight. This vitamin helps to build cartilage and to maintain healthy bone density. Vitamin D is found in oily fish and eggs, but the majority of people suffer a deficiency, if only slight in many cases. Discount vitamin supplements containing all of these vitamins and minerals will help to maintain healthy joints. Vitamin A is available naturally from eggs yolks, oily fish and dairy products, and most people know that vitamin C is obtained from fresh fruit and vegetables, especially the highly colored foods that are also rich in other antioxidants such as anthocyanins and carotenoids. Rich sources of vitamin E include nuts, seeds, vegetable oils and wheat germ. Taking Omega 3 oil supplements will not prevent arthritis, but will help to relieve the inflammation and hence the pain. However, in spite of all of this, the only vitamin that has been extensively tested on patients suffering from osteoarthritis has been vitamin E. It has been established that significant improvements in the condition of patients were achieved by administering from 400-600 International Units (I.U.) of vitamin E daily for two weeks. Another substance that is a component of connective tissue and that can be taken to help rebuild what is lost in joint disease is hyaluronic acid. This chemical is found all over the body, and involved in the structure of many types of connective tissue, including the joints, the vitreous humor of the eyes and heart valves. In the joints it is rich in the synovial fluid that lubricates the joints, and also found in cartilage. Although hyaluronic acid is contained in chicken soup, it is obtained mainly from rooster combs, then treated to reduce its molecular size so that it can be absorbed. Anybody allergic to chicken should seek their doctor’s advice on taking hyaluronic acid as a supplement. It is highly recommended that a vitamin supplement be taken by anybody suffering from any form of arthritis or joint disease, but it is Glucosamine that appears the best treatment for long term success. Glucosamine is a very large molecule, and it is difficult to get it to the site of the problem. To get to the joint, the molecule has to pass through the capillaries, and very few Glucosamine molecules can actually achieve that. That is why the doses are so large, so that even if only a small percentage gets to the joint then that is enough to help rebuild cartilage. The antioxidants help to destroy the root cause of many forms of joint disease: the free radicals and anti-inflammatories can help relieve pain. However Glucosamine and chondroitin not only relieve the pain, but also continue to work over time to repair the joint tissues. As with most supplements the body can only absorb so much Glucosamine, only consume 500mg at a time but take it two to three times each day for best results. Glucosamine is often provided in conjunction with MSM (Methylsulfonylmethane) that is a natural form of dietary sulfur. Sulfur is believed to be essential for healthy soft connective tissues, tendons and so on. Calcium, too, is a useful supplement to take since it help to recover the bone density, but keep in mind that vitamin D is essential for the uptake of calcium, so a vitamin D supplement will be required along with the calcium. Although calcium will not in itself help joint disease, it will help to main a good bone density that is more capable of withstanding the stresses of a reducing cartilage density. There is therefore quite a wide variety of vitamins, minerals and other substances that can help to support healthy joint function, and also to help repair joint damage, and discount vitamins are the best way to tackle the problem of maintaining a good intake of those that are most effective, namely, Glucosamine and chondroitin sulfate, vitamins A, C, D and E, and supplemental MSM, hyaluronic acid and calcium. You do not need them all, but only testing will enable you to decide which work for you. You should also contact your physician before taking discount vitamin supplements if you have any other medical problems.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1638) Safe Solutions for Chronic Pain
Date:
March 30, 2007 12:09 PM
Safe Solutions for Chronic Pain One of the biggest challenged in healthcare today is the problem of pain. There are simply too many people living each and every day with ongoing, unremitting chronic pain. And there are far too many healthcare providers who – for a variety of reasons – are failing to adequately address this serious problem. Recently, 368 doctors who routinely care for patients with chronic pain agreed to take part in a unique study. The doctors were surveyed about the pain medicines hey prescribe, what kind of treatment goals they hope to achieve, and how they felt about their ability to help their patients. They were also presented with four chronic pain vignettes or mock case studies and asked to select the best treatment for each scenario from multiple choice answers. Sadly, many doctors chose the worst treatment options in the case studies. The medications they reported using in their practices did not reflect current pain treatment standards. They tended to set low treatment goals 0 instead of aiming for a least a 75% reduction of pain for their patients, they settled for 10% to 20% reductions. And many of the doctors admitted they lacked confidence in their ability to relieve their patients’ pain and suffering. Adding to the challenge are the almost daily news announcements about dangerous side effects in certain pain medications. Synthetic prescription COX-2 inhibitors, once hailed as the safest of drugs, have been linked to heart attacks, strokes, blood clots, and intestinal bleeding. The over-the counter (OTC) drugs aspirin and ibuprofen kill over 16,000 people each year. And acetaminophen, the most widely used pain reducer in the As a doctor specializing in chronic pain disorders, I know that optimal pain management can be a real challenge. However, I also know: -You do not have to live in chronic pain. -Your chronic pain, no matter what the cause, can be reduced, and usually eliminated. -Chronic pain can be relived both effectively and safely with powerful all-natural compounds. Q. What is chronic pain? A. Sudden, or acute, pain occurs when pain signals immediately fire in your nervous system alerting you to an injury, like a broken ankle, or an illness, such as appendicitis. Once the injury heals or the illness is cured, the transmission of pain signals stop. Ongoing – or chronic pain – is much different. Chronic pain persists. Pain signals keep firing in the nervous system for weeks, months, even years. There may have been an initial injury, such as sprained back muscles, or an initial illness, such as a serious infection. There might be an ongoing cause of pain, such as arthritis, cancer, or fibromyalgia. Chronic pain also occurs without any past injury or evidence of body damage. The most common kinds of chronic pain are headache, low back pain, cancer pain, arthritis pain, and neurogenic pain (pain resulting from damage to nerves or to the nervous system itself). While chronic pain differs in its origin and where it occurs, it is generally your body’s way of saying that something urgently needs attention, and will not o away unless its underlying causes are addressed. These causes can usually be determined if you remember the acronym “SHIN”. This stands for Sleep, Hormonal deficiencies, Infections/Inflammation/Impingement, and Nutritional deficiencies. When these are treated, pain often resolves. Q. Why is it so hard to effectively reduce chronic pain? A. Unfortunately, many physicians’ entire education in pain management consists of “giving nonsteroidal anti-inflammatory drugs or NSAIDs (pronounced en-sayds), COX-2 inhibitors, or acetaminophen and considering narcotics if the patient has cancer. Some NSAIDs, like aspirin and ibuprofen, are available over-the-counter, while others, like the synthetic COX-2 inhibitors are only available with a doctor’s prescription. These mediations are usually inadequate and often toxic when used for chronic pain. And they do not address the problem(s) that the pain is trying to alert you to. Q. What exactly are COX-2 inhibitors? A. COX-2 inhibitors do pretty much what their name implies – they inhibit a natural enzyme in our body called the clclooxygenase-2, or COX-2, enzyme. There are two COX enzymes – COX-1 and COX-2 and both complete several actions in our bodies. One very important action that both COX-1 and COX-2 enzymes share is the speeding up of our body’s production of prostaglandins. These hormone-like substances are made by the cells of the body and have several important functions. Some of the most powerful prostaglandins cause inflammation, pain, and fever when we are sick or injured. Prostaglandins also protect the lining of the stomach from the damaging effects of acid. Other prostaglandins make sure our platelets (important blood cells) make blood clots when needed. Still others help our kidneys get rid of unwanted salt and water. And researchers have just recently recognized the importance of still another prostaglandin that protects our heart and blood vessels. The NSAIDs reduce pain by reducing prostaglandin production by blocking or inhibiting the COX enzymes. In theory – less prostaglandins, less pain and welling seems reasonable. But if you really stop and think about it, it’s pretty easy to understand why this method of pain relief might result in significant consequences. Pain and inflammation are often needed for healing. And just as needed is the protection of our stomach lining, blood clotting ability, assisting kidney function, and keeping our blood vessels healthy. And scientists are beginning to understand if you interfere with one natural response, you may be disrupting the body’s ability to prevent extremes and imbalances. That’s why using aspirin and ibuprofen can result in stomach ulcers, kidney problems, and internal bleeding. And that’s why using synthetic COX-2 inhibitors can result in high blood pressure, blood clots, heart attacks, and strokes. Q. Why are we just now learning about the dangers of COX-2 inhibitors and other NSAIDs? A. That’s a good question! Many people over the age of 65 have chronic pain conditions and are frequent users of OTC and prescription NSAIDs. This age group also experiences heart disease and Alzheimer’s disease in greater numbers. So, if a 70 year old woman who’s been using Celebrex for the past two years for arthritis in her knees suddenly has a heart attack one morning, it would not be entirely unexpected. For the past five or six years, researchers have been studying the possibility that NSAIDs may prevent certain cancers, Alzheimer’s disease, and other health problems. The ongoing, close scrutiny of large group of people taking these medications by scientists who were conducting these studies has resulted in the discovery of these dangers. Q. What kind of natural compounds relieve chronic pain? A. There are many – Glucosamine, Omega-3 fatty acids, the B vitamins – the list goes on and on. Instead of disrupting normal bodily responses, these natural compounds work in harmony with our body to eliminate chronic pain. Three very powerful and very effective all natural plant compound pain and inflammation relievers are Sweet Cherry, Boswellia serrata, and White Willow Bark. For many years there have been anecdotal or personal reports that claimed eating Sweet Cherries, specifically Prunus avium, wipes out back pain, arthritis, and gout. While anecdotal reports generally don’t account for much in the world of science, he sheer numbers of testimonials proclaiming the Sweet Cherry’s amazing ability to reduce pain made researchers sit up and take notice. When Sweet Cherries were examined in the lab, it was easy for scientists to understand how this natural fruit is able to relieve pain. It seems Sweet Cherry’s bright red color is the key. Like many deeply colored fruits, Sweet Cherries are full of flavonoids called anthocyanins and proanthocyanidins. These powerful plant compounds scavenge and destroy altered oxygen compounds called free radicals. Many degenerative, chronic diseases have been associated with the tissue damage caused by free radicals, including arthritis, heart disease, peripheral artery disease, and cancer. Cherry fruit extract is a natural anti-inflammatory compound, making it an excellent treatment for arthritis, fibromyalgia, and other chronic pain and inflammation diseases. A pain relieving plant compound that comes from the bark of a tree, Boswellia serrata has been used by Indian healers for hundreds of years to reduce painful inflammation. When 20th century researchers looked at extracts of Boswellia Gum Resin in the laboratory they discovered the presence of powerful plant compounds, called boswellic acids. Researchers found Boswellic Acids reduce inflammation in several ways. They open constricted blood vessels, improving blood flow to joints. They balance levels of leukotrienes – specific chemicals in the body that cause inflammation. And Boswellic Acids block two inflammatory chemicals that increase in asthma and inflammation of the colon. In addition to being helpful in treating these 2 illnesses, Boswellia has also been clinically studied and found to be quite effective in osteoarthritis and rheumatoid arthritis without any evidence of ulcers or stomach irritation. Another bark extract, White Willow Bark is one of the oldest and most effective pain relievers. For over 2,000 years extracts from the bark of the White Willow tree have been used to ease aches and pains and reduce fevers. It is the original source of aspirin, but when used as the entire plant medicine, White Willow Bark is much safer than aspirin and quite effective. White Willow Bark’s active ingredient is salicin and the combination of other compounds in the bark significantly enhances its pain killing power. In two large clinical trials of patients with chronic low back pain. White Willow Bark was found to be not only safer and much more effective than standard prescription therapies, it was also 40 percent more cost effective. Salicylic acid from White Willow Bark lowers the body’s levels of prostaglandins, easing both acute and chronic pain. White Willow Bark reduces the pain and swelling of arthritis, headache, back and neck pain, muscle aches, and menstrual cramps. But, unlike aspirin, it doesn’t cause stomach bleeding or other known adverse effects. Q. Do Sweet Cherry, Boswellic Acids, and White A. They do indeed. Because they reduce both pain and inflammation by a broad combination of actions, these natural extracts have been proven to be excellent against arthritis, back pain, and pain from inflammatory intestinal diseases (Crohn’s disease and ulcerative colitis), and would be expected to be helpful in most kinds of pain. Sweet Cherry, Boswellic Acids, and White Willow Bark relieve inflammation without causing stomach irritation, stomach ulcers, high blood pressure, blood clots, heart attacks, or strokes. That’s because these natural pain killers don’t disrupt the balance of enzymes or interfere with the body’s ability to prevent extremes and imbalances. However, as with any pain therapy, Sweet Cherry, Boswellic Acids, and White Willow Bark work best when they are used as part of a comprehensive treatment plan to relieve the most common underlying causes of chronic pain or SHIN. In addition, although these excellent natural remedies can often offer quick pain relief, natural remedies for severe chronic pains work best when they are given at maximum allowed doses and given 6 weeks to show their full effectiveness in combination with treating the pain’s underlying causes. The best chronic pain relief results when doctors and patients work together to meet the goals of treatment. Some important last notes: Many causes of chronic pain are serious and life threatening. Everyone who is living with chronic pain must consult their doctor or other healthcare practitioner to determine the reason for their ongoing discomfort. In other words – make sure you know why you are having chronic pain and what’s causing the pain you want to relieve. There are some types of chronic pain that only respond to opioids, or narcotic pain relievers. Morphine sulfate is an excellent pain medication and is used to relieve surgical pain, the pain of heart attacks, and pain from serious injuries. Morphine is also the very best drug for chronic cancer pain and non-malignant chronic pain. While many people fear opioids, these powerful pain killers can dramatically improve quality of life. If you are suffering with chronic cancer pain and you are hesitant to use morphine or another opioid, I urge you to discuss your concerns with your doctor other healthcare provider. No one with cancer should live with untreated or under-treated pain. Conclusion Even chronic pain can often be eliminated when SHIN is in combination with powerfully effective natural pain relievers. But, because some people may need to take pain relievers the rest of their lives, the medications they use must be safe as well as effective. The very safest come from natural plant compounds that have been studied for their ability to relieve chronic pain. You can become pain free and Sweet Cherries, Boswellic Acids, and White Willow Bark can help.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1503) Glucosamine Sulfate and Chondroitin Sulfate
Date:
March 28, 2007 11:10 AM
Glucosamine Sulfate and Chondroitin Sulfate Osteoarthritis is the most prevalent form of arthritis in the U.S., according to the Arthritis Foundation. One-third of all American adults have X-ray evidence of osteoarthritis of the hand, foot, knee, or hip. Osteoarthritis is responsible for more than 7 million physician visits per year and is second only to cardiovascular disease as the cause of chronic disability in adults. As Baby Boomers age, the number of people suffering from osteoarthritis is expected to rapidly increase in the next 10 years. While osteoarthritis research ahs led to the development of promising new prescription and over-the-counter medications aimed at reducing pain, none has created the excitement of Glucosamine sulfate (GS), which actually addresses the underlying joint destruction. Q. What is osteoarthritis? A. Osteoarthritis is a complex, metabolic disorder of the cartilage and bones of certain joints. However, to fully understand how osteoarthritis develops, we need to understand how joints work. A joint is formed when two or more bones are brought together and held in place by muscles and tendons. Some joints have very little range of movement, such as the joints of the ribs, while others have much more range of movement. Hips, knees, elbows, writs, and thumbs are termed synovial joints, and have the greatest range of movement and mobility of human joints. To allow such mobility, synovial joints have a unique structure. The bones that form synovial joints are covered with cartilage. Tough fibrous tissue encloses the area between the bone ends and is called the joint capsule. The joint cavity within the capsule is lined with an inner membrane, called synovial membrane. The membrane secretes synovial fluid, a thick, slippery fluid that fills the small space around and between the two bones. This fluid contains many substances that lubricate the joint and ease movement. The cartilage of synovial joints serves two very important functions. First, it provides a remarkably smooth weight-bearing surface; synovial joints move easily. Secondly, synovial cartilage serves as a shock absorber, providing a soft, flexible foundation. Healthy cartilage absorbs the force of the energy, transmits the load to the bone, and distributes the mechanical stress created by joint movement. Synovial joints function under almost continual mechanical stress. A joint’s ability to withstand or resist this stress is a reflection of its health. When the mechanical stress is too great or the joint’s ability to resist this stress is compromised, physical changes occur in the cartilage covering the bones. Cartilage is a tough, elastic tissue, comprised mostly of water, collagen, and complex proteins called proteoglycans. In osteoarthritis, the cartilage starts to weaken, becomes frayed, and eventually breaks down. This exposes the bones of the joint, which then rub together. A gritty feeling and grinding sound may occur when an osteoarthritic joint is bent and flexed. As osteoarthritis progresses, bits of bone and cartilage often break off and float inside the joint space. The bones may enlarge, causing the joint to lose its normal shape. Tiny bone spurs may grow on the joints’ sides and edges. These physical changes in the diseased joint are responsible for progressive damage and continual pain. People with osteoarthritis most frequently describe their pain as deep and aching. The pain not only is felt in the affected joint but may also be present in the surrounding and supporting muscles. Joint inflammation also may occur, increasing the already considerable discomfort. Joint stiffness is another unfortunate component of osteoarthritis. Exercising the joint most often results in increased pain; however, stiffness tends to follow periods of inactivity. Humid weather often makes all osteoarthritis symptoms worse. As the disease progresses, the pain may occur even when the joint is at rest, creating sleepless nights and miserable days. Q. What causes osteoarthritis? A. Osteoarthritis’ exact cause remains unknown. Researchers know aging doesn’t appear to cause osteoarthritis. Cartilage in people with the disease show many destructive changes not seen in older persons without the disease. However, certain conditions do seem to trigger osteoarthritis or make it worse. Some families seem to have a lot of osteoarthritis, pointing to a genetic factor. This is most commonly seen in people who have osteoarthritis of the hands. Repeated trauma can contribute to osteoarthritis, too. Athletes, extremely active people, and individuals who have physically demanding jobs often develop the disease. Persons who have certain bone disorders are more prone to osteoarthritis due to the continuous, uneven stress in their hips and knees. Obesity also is a risk factor for the disease. In overweight women, osteoarthritis of the knee is fairly common. Excess pounds also may have a direct metabolic effect on cartilage beyond the effects of increased joint stress. Obese people also often have m ore dense bones. Research has shown dense bones may provide less shock-absorbing function than thinner bones, allowing more direct trauma to the cartilage. Q. Can osteoarthritis be prevented? A. While there is currently no sure way to prevent osteoarthritis or slow its progression, some lifestyle changes may reduce or delay symptoms. The Arthritis Foundation states that maintaining a healthy weight, losing weight if needed, and regular exercise are effective osteoarthritis prevention measures. Optimal calcium intake in younger years is vital to ensure a healthy aging skeletal system. Vitamins A, C, D, and E have been studied for their role in osteoarthritis prevention. These vitamins also have shown benefit in individuals who have osteoarthritis. Q. What treatments are available for osteoarthritis? A. The goal of treatment is to reduce or relieve pain, maintain or improve movement, and minimize any potential permanent disability. Typically, non-steroidal anti-inflammatory drugs or NSAIDs (pronounced “n-sayds”) such as aspirin and ibuprofen are used for pain and inflammation relief. These medications are effective in treating only the pain of osteoarthritis. These medications have many side effects, some of which are serious. NSAID-induced gastrointestinal complications cause more than 100,000 hospitalizations and nearly 16,500 deaths annually in the U.S. Aspirin can cause an extremely annoying and continual ringing in the ears. NSAIDs frequently cause damage to the stomach lining, which can produce uncomfortable heartburn and abdominal pain. Continued NSAID use may lead to the development of stomach ulcers. NSAID-related ulcers can perforate the stomach lining and cause life-threatening bleeding. Most NSAIDs also interfere with blood clotting and may cause kidney damage. When older persons take NSAIDs, dizziness, drowsiness, memory loss, and decreased attention span may occur. Acetaminophen (Tylenol and similar medications) is similar to aspirin and other NSAIDs in its pain-relief abilities. However, acetaminophen doesn’t reduce inflammation. And while acetaminophen doesn’t have the same side effects of aspirin and other NSAIDs, if large doses are taken, liver damage can occur. Newer medications called COX-2 inhibitors provide both pain relief and reduce inflammation without the many side effects of acetaminophen, aspirin, and other NSAIDs. More recent research has indicated that, in certain situations. COX02 inhibitors also can cause stomach lining damage and bleeding. While aspirin, NSAIDs, and COX-2 inhibitors may reduce osteoarthritis pain, they do nothing to stop or slow down cartilage deterioration. In other words, these medications have no effect on the disease itself. That is why many believe Glucosamine sulfate (GS) and chondroitin sulfate (CS) are preferable to pain relievers and anti-inflammatory medications in osteoarthritis treatment: they actually improve synovial joint health. And they do this without potentially life-threatening side effects. Q. How do GS and CS work? A. GS improves the health of joints affected by osteoarthritis. This supplement is so effective that even physicians who mostly rely on conventional medications routinely recommend it to their patients with osteoarthritis. In fact, GS is so good at treating osteoarthritis, many physicians use it for their own osteoarthritis joints. There is even more good news. When Glucosamine sulfate is combined with low-molecular weight CS, even greater benefits can be achieved. GS and CS are naturally occurring compounds found in human joints. The right GS/CS combination actually reverses damage in joints affected by osteoarthritis, in turn significantly reducing pain and stiffness. Glucosamine occurs naturally in the body and is found in synovial fluid. Glucosamine is a basic building block for proteoglycans, is a basic building block for proteoglycans, one of the important compounds of synovial cartilage. It also is required for the formation of lubricants and protective agents for the joints. In Europe, GS and CS have been used to treat osteoarthritis for more than 10 years. While persons with arthritis felt much better when they took GS and CS, no one really knew how these compounds worked. When European and American researchers first started to study Glucosamine, they discovered GS can reduce synovial joint inflammation. This explains why people felt better after taking it. Q. What has additional study of GS and CS revealed? A. As the scientific study of GS progressed, researchers determined it can stimulate the growth of cartilage cells, inhibit proteoglycans breakdown, and rebuild cartilage damaged from osteoarthritis. In other words, GS does not simply make persons with osteoarthritis feel better; GS actually makes persons with osteoarthritis get better. GS is the form of Glucosamine used in research. It’s the sulfate salt of Glucosamine and breaks down into Glucosamine and sulfate ions in the body. The sulfate part of GS plays an important role in proteoglycans synthesis. CS also provides cartilage strength and resilience. CS is an important component of the cartilage proteoglycans of synovial joints. Because CS helps the production of proteoglycans, researchers believe CS works in a similar nature to GS. Q. Couldn’t GS and CS be taken on their own? Is there any benefit in taking them together? A. Research has discovered GS and CS act synergistically (work well together) in improving joint health. Several studies have investigated this action and it’s recommended that GS and CD be taken together. However, there may be times when your healthcare practitioner may recommend using one or the other, but not both GS and CS together. Please follow their recommendations to obtain the best results for your own unique health concerns. Low-molecular weight chondroitin sulfate (CS) is the preferred CS form, and the form that has shown the most promise in studies. Q. Why is it important to take low-molecular weight CS? A. When CS was first studied, it was given to six healthy volunteers, six patients with rheumatoid arthritis, and six patients with osteoarthritis. Researchers then measured the levels of CS in all study subjects. They found no evidence of CS in any of the subjects. This single study led many physicians and scientists to believe CS can’t be absorbed, and was not an effective natural treatment. However, several other studies in healthy volunteers have reported CS can be absorbed. The distinct difference for these findings is thought to be associated with the types of CS used in the studies. Some forms are much more absorbable that others. This was demonstrated in a recent study using CS with lower molecular weight. A higher absorption is observed for low-molecular weight CS. This means CS products with a low molecular weight may be better absorbed, allowing the CS to get into the bloodstream and the synovial fluid of joints where it’s needed. Q. Are there other supplements that can help osteoarthritis? A. Several vitamins, minerals, enzymes, and natural supplements have benefits for individuals with osteoarthritis. Proteolytic enzymes effectively offer relief of the pain, stiffness, and swelling of osteoarthritis. Folic acid and vitamin B can reduce the number of tender joints and increase joint mobility. Vitamins C, D, and E not only may prevent osteoarthritis, but inhibit the disease’s progression. Niacinamide improves joint function, range of motion, and muscle strength. Clinical studies using the herb Boswellia serrata have yielded good results in osteoarthritis. Application of ointments on osteoarthritic joints may be helpful in reducing pain and stiffness. Menthol-based preparations can provide soothing relief to painful joints. Capsaicin ointments and gel made for cayenne pepper also are very beneficial. When applied to the skin, capsaicin first stimulates, then blocks, nerve fibers that transmit pain messages. Capsaicin depletes nerve fibers of a neurotransmitter called substance P. This neurotransmitter transmits pain messages and activates inflammation in osteoarthritis. Capsaicin ointment is very effective in relieving osteoarthritis pain in many individuals. Q. Is there anything else I can do for joint pain and stiffness? A. When osteoarthritis occurs in the hands, use of a paraffin dip can be very comforting. A licensed health care practitioner can provide information about how to safely use paraffin dips at home. Exercise is an excellent way to keep joints mobile, decrease pain, and increase body strength, too. Water aerobics also can reduce the pressure and stress on joints. The Arthritis Foundation strongly suggests making movement an integral part of your life. When you’re in less pain and have more energy, more range-of-motion, and a better outlook on life, you’ll reduce stress and be a much healthier person despite your osteoarthritis. One important last thought When we don’t feel well, we sometimes have a tendency to self-diagnose. If you haven’t been evaluated by a licensed health care practitioner for your joint pain and stiffness, you need to do so. These symptoms may be caused by other illnesses and may require much different treatment. Only licensed health care practitioner can provide a certain diagnosis of osteoarthritis. Conclusion Osteoarthritis may be a part of life for many of us as we age; however, constant pain and stiffness need not be. GS combined with absorbable CS can actually improve damage in joints affected by osteoarthritis and significantly reduce pain and stiffness. And it can be an empowering way to improve your health. Buy Glucosamine and Chondroitin Sulfate at Vitanet ®, LLC
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1500) Hip & Joint Defense Plus Bone Meal
Date:
December 31, 2005 09:58 AM
Hip & Joint Defense Plus Bone MealProvides Glucosamine, MSM, and Bone meal to support strong bones, joint flexibility and hip health, good for all sizes and breeds.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1143) JOINT HEALTH
Date:
December 22, 2005 09:37 AM
Glucosamine & Chondroitin - JOINT HEALTHEveryone old enough to walk appreciates the value of fl exibility and ease of movement. Unfortunately many of us take such good things for granted. A famous folksinger sang, “You don’t know what you’ve got till it’s gone.” That’s certainly true for millions of Americans who live with stiff and uncomfortable joints. Fortunately there are a number of nutrients available that provide the vital components of healthy joint structure and function and ease of mobility. These nutrients are referred to as “chondroprotective agents,” and include Glucosamine and chondroitin, which supply the raw material necessary to produce new cartilage, and may even help rebuild worn cartilage. Other chondroprotective nutrients and herbs, like Cetyl Myristoleate, MSM, and Boswellin, work synergistically with Glucosamine and chondroitin and further support normal joint function To understand how chondroprotective agents work, one must fi rst understand how joints work. The key element in human joints is articular cartilage, the shock-absorbing tissue that connects two bones together and allows pain-free movement. Articular cartilage is comprised of two different molecules, collagen and proteoglycans, with the remainder composed primarily of water (65-85%). Collagen, a protein that binds tissue together, provides elasticity. Proteoglycans, composed of sugars and protein, absorb water, which provides lubrication and resiliency, nature’s shock absorber for your joints. Both compounds are produced by chondrocytes, caretaker cells responsible for the formation and maintenance of cartilage. A defi ciency in any one of the above constituents will increase the likelihood of wear and tear on articular cartilage, which can eventually lead to compromised joint function. Glucosamine and chondroitin are safe, natural and effective nutrients that support healthy joint function by supplying the materials needed to produce collagen and proteoglycans.
GlucosamineGlucosamine is composed of glucose (a sugar) and glutamine (an amino acid). It is utilized by chondrocytes to form glycosaminoglycans (GSG) and proteoglycans (PG). Both of these constituents attract and bind water into cartilage, increasing resiliency. Research indicates that Glucosamine may actually help your body repair damaged or eroded cartilage. A number of studies have been conducted on Glucosamine sulfate and Glucosamine hydrochloride, with a preponderance of positive results. Glucosamine sulfate is considered the more effective of the two. One study from the University of Liege in Liege, Belgium studied the effects of Glucosamine sulfate on 212 patients with knee osteoarthritis. Participants took either 1,500 mg Glucosamine or a placebo once daily for three years. The study compared joint-space width at enrollment, one year, and at the study’s conclusion. The 106 patients on placebo had a progressive jointspace narrowing, while participants taking Glucosamine experienced no significant joint-space loss, indicating Glucosamine may benefi cially modify cartilage structure.3 A study published in the journal Osteoarthritis and Cartilage in 1998 investigated the in vitro effects of Glucosamine sulfate on proteoglycan and collagen production by chondrocytes taken from osteoarthritic articular cartilage. The results showed “a statistically signifi cant stimulation of PG production by chondrocytes from human osteoarthritic cartilage cultured for up to 12 days in 3-dimensional cultures.” 4 Another study from Italy enrolled eighty inpatients with established OA. They received either 1,500 mg of Glucosamine sulfate or placebo daily for 30 days. The patients treated with Glucosamine sulfate experienced a reduction in symptoms almost twice as large and twice as fast as those receiving placebo. Researchers also used electron microscopy of patient’s articular cartilage to support this hypothesis. Patients who received Glucosamine sulfate showed a picture more similar to healthy cartilage. The researchers concluded that Glucosamine sulfate tends to rebuild damaged articular cartilage and restore articular function.5
CHONDROITINChondroitin is classifi ed as a glycosaminoglycan. It bonds with collagen to form the basis of connective tissue. Chondroitin helps attract fl uid into proteoglycans, thereby bringing nutrients into cartilage and providing shock absorption. While Glucosamine helps manufacture and maintain cartilage, chondroitin keeps cartilage from becoming malnourished. Chondroitin works synergistically with Glucosamine, and these two nutrients form the basis of most joint health supplements on the market today. A 6-month randomized, multi-center, double-blind, doubledummy study published in 1996 compared the effectiveness of chondroitin versus a popular non-steroidal anti-infl ammatory drug (NSAID) in patients with knee osteoarthritis (OA). One hundred and forty-six patients with knee OA were recruited and separated into two groups; an NSAID group and a chondroitin sulfate (CS) group. The NSAID group was given the NSAID and a placebo for the fi rst month, then placebo alone for months 2-3. The CS group was given the NSAID and CS for the fi rst month, and then CS alone for months 2-3. Both groups were then given 1200mg of CS for months 4-6. “Patients treated with the NSAID showed prompt and plain reduction of clinical symptoms, which, however, reappeared after the end of treatment; in the CS group, the therapeutic response appeared later in time but lasted for up to 3 months after the end of treatment. CS seems to have slow but gradually increasing clinical activity in OA; these benefi ts last for a long period after the end of treatment.”6 NOW® Foods is your source for natural joint support products. Our Extra Strength Glucosamine & Chondroitin is one of our best-selling products, and we also have combination supplements that include MSM, Concentrace® minerals, and more. We also carry both Glucosamine and chondroitin as separate products, as well as in powder and lotion forms.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1064) - US Center for Disease Control, 2005
Date:
December 07, 2005 01:27 PM
“Forty-three million Americans report that a doctor told them they have arthritis or other rheumatic conditions. Another 23 million people have chronic joint symptoms but have not been diagnosed with arthritis. Arthritis is the leading cause of disability in the United States, limiting the activities of more than 16 million adults.” - US Center for Disease Control, 2005 This is of alarming concern, especially if you’re one of the nearly 60 million US adults who live with a joint disorder. Clearly, you don’t need to be reminded of what a struggle it can be. Mundane tasks become major, and major tasks become painful reminders of what life was like when your joints were strong and seemingly indestructible. Many sufferers lose hope, while others hopelessly lose out on so many of life’s activities. Over the past ten years, notable advances in the nutritional sciences have paved the path for landmark products such as Glucosamine, SAMe, Chondroitin, MSM, and others. As a result, millions have found relief in these products and continue to use them in their quest towards healthy mobility. Fortunately, the science behind these popular joint support supplements has done nothing but steadily improve. Celadrin® is perhaps the most convincing proof to date. Let’s examine. In short, Celadrin® is novel blend of acetylated fatty acids, esters and other synergistic agents that enhance cell membranes throughout the body, resulting in greater mobility and more normalized joint function. The extremely high user success rate and virtually complete absence of side effects has helped Celadrin® rise to the rank of joint support extraordinaire. Yes, this is a bold statement. However, just one look at the supporting research is enough to convince even the most skeptical critics of what a true breakthrough it is. Celadrin®’s ability to provide fast, cumulative relief continues to be evidenced by extensive clinical research, as well as a steady flow of eye-opening human trials. Unlike popular non-steroidal anti-inflammatory drugs (NSAIDS) that simply mask joint discomfort, Celadrin® targets the source by enhancing cell membranes and restoring the vital fluids that cushion bones and joints. Ultimately, this is what makes it possible to enjoy a free range of motion without the bone-on-bone grinding that limits so many from their daily activities. Working in much the same manner that other fatty acids do, Celadrin®’s patented blend of esterified fatty acids spark positive changes at the cellular level. As this occurs, cell membranes become more responsive and less prone to articular cartilage deterioration. “How long do I need to take it?” Not only does it work well, studies continue to illustrate Celadrin®’s ability to work fast. This can be attributed to how easily absorbed the active ingredients are. In 2005, a University-led, placebo-controlled study examined 42 patients who struggled with knees that were…let’s just say less than fully functional. After just 30 minutes, 100% of the subjects treated with a topical form of Celadrin® reported significant improvement in joint mobility and support. Even more impressive, each participant demonstrated continuous and restorative benefits over the course of the entire 30 day study. “How do I use Celadrin®?” One of the most appealing elements of Celadrin® is the flexibility that users have when it comes to taking charge of their joint health. It is available in both oral and topical forms, and each is equally effective. Some users have reported greater results by supplementing the oral form while applying the topical lotion directly to the target areas in question. Still, no two people are alike. Accordingly, the severity and nature of each individual concern will vary from person to person. Therefore, it can be wise to determine which application works best for your particular situation. “What if I don’t have joint problems?” For openers, you’re very fortunate. If your joints are strong and fluid, Celadrin® is one of the most effortless ways to keep them that way! Cartilage breakdown is gradual, and occurs over a long, delayed, unsuspecting period of time. In many cases, there is very little warning that your knee or shoulder is about to become part of a frightening and growing statistic. Your joints may feel fine today, but you’d be amazed at how fast that can change. Think of Celadrin® as Cartilage Insurance. You may not see an immediate need to support them right now, but if they do give out, you’ll sincerely wish you had. “What should I look for in a Celadrin® product?” As with every dietary supplement and joint-support product, you should always look for a quality formula from a trusted, well-established manufacturer with a history of producing quality products. NOW® Celadrin® products are scientifically formulated, tested for safety and potency and guaranteed to be of superior quality. Each full serving contains 1.5 g (1500 mg) of Celadrin® along with 300 mg of MSM for additional support. NOW® Celadrin® Liposome Lotion contains 7.5 % Celadrin® along with 1.25% USP Pharmaceutical grade natural Menthol. Both are now available at fine independent health food retailers nationwide.* credits: Jayson Kroner [mailto:jayson.kroner@nowfoods.com]
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=986) Celadrin and MSM Fact Sheet
Date:
December 07, 2005 01:24 PM
Celadrin and MSM Fact SheetNeil E. Levin, CCN, DANLA Certified Clinical Nutritionist, Diplomate in Advanced Nutritional Laboratory Assessment Revised 11/10/05LIKELY USERS: People lacking flexibility or mobility; People wanting temporary control of aches and pains; People wanting to reduce pro-inflammatory body chemicals. KEY INGREDIENT(S): Celadrin® powder 500 mg. Provides 350 mg. of actual EFAC (esterified fatty acid carbons). This is a proprietary blend of Esterified Fatty Acid Carbons of Myristate, Myristoleate, Laurate, Oleate, Palmitate and Palmitoleate in a base of tapioca and silica. MSM 100 mg. MAIN PRODUCT FEATURES: CELADRIN® is an all-natural proprietary matrix of esterified (cetylated) fatty acid carbons (EFAC) derived from tallow of USA-raised cattle. This product is developed through a proprietary process of esterifying oil & has been clinically tested. Celadrin promotes joint health by improving flexibility, pain management and mobility. The myristoleic acids and the cetylated forms may alter the 5-LOX enzyme and change the leukotriene production, inhibiting inflammatory compounds. Celadrin® may offer some noticeable benefits faster than other substances, like Glucosamine and chondroitin. Though it is not a substitute for these important tissue-building nutrients. ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: MSM has synergistic abilities to reduce certain substances in the body which may affect the inflammatory process. Contains Cetyl Myristoleate (CM, CMO), but in a patented blend of other fatty acid carbons. This product (Celadrin ®) has its own clinical studies showing safety and efficacy. Also will be available in a softgel of the same potency (350 mg. of EFAC) as of December 2005 (product 3017, 90 softgels) SERVING SIZE & HOW TO TAKE IT: Three capsules a day, preferably with meals. POSSIBLE SYNERGISTS: Glucosamine, Chondroitin, MSM, Joint Support Products, Manganese, Vitamin C, other Antioxidants CAUTIONS: None. SPECIFIC: None GENERAL: Pregnant and lactating women, and people using prescription drugs, should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. This document has not been reviewed by the FDA or by the company posting it. Information given here may vary from what is shown on the product label because this represents my own professional experience and understanding of the science underlying the formula and ingredients. When taking any new dietary supplement, use common sense and cautiously increase to the full-recommended dose over time, looking for possible side effects. Repeat this process for each new supplement that you start to use.
REFERENCES: 1. J Rheumatol. 2002 Aug;29(8):1708-12. Cetylated Fatty Acids Improve Knee Function in Patients with Osteoarthritis. Hesslink R Jr, Armstrong D 3rd, Nagendran MV, Sreevatsan S, Barathur R.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=985) NEW PRODUCT ANNOUNCEMENT - Hyaluronic Joint Complex
Date:
August 03, 2005 01:27 PM
NEW PRODUCT ANNOUNCEMENTHyaluronic Joint Complex ™ with Glucosamine, Chondroitin and MSM The Next Generation in Joint Formulas!
2 tablets contain: BioCell Collagen is a trademark of Biocell Technology LLC, Newport Beach, California USA (US patent 6,025,327 - other USA and foreign patents pending). OptiMSM is a trademark of Cardinal Nutrition. Suggested Use: 2 tablets twice daily, or as recommended by your health care professional.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=722) Hyaluronic Joint Complex - w/Glucosa, Chondr, & MSM - The Next Generation in Joint Formula
Date:
June 29, 2005 11:45 AM
Hyaluronic Joint Complex™ with Glucosamine, Chondroitin, and MSM The Next Generation in Joint Formulas Every movement you make requires your joints to help your body flex, bend and twist into that next position. But with time and use, your joints can begin to break down, resulting in discomfort. Source Naturals understands how difficult it is to live with joint discomfort. That’s why we developed HYALURONIC JOINT COMPLEX. This powerful formula combines the most popular, scientifically researched ingredients for joint health—hyaluronic acid, Glucosamine, chondroitin, and MSM. Together, these ingredients promote joint, tendon and ligament flexibility and easy joint movement. Joints are cushions made of flexible and protective cartilage—containing outer layers that surround a lubricating fluid. It is this design of your joint and other connective tissues that gives your body structure, height and the ability to move without damaging the bones and muscles that hold you up. HYALURONIC JOINT COMPLEX provides the key nutrients needed to support this complex structure. BioCell Collagen II®—Hyaluronic Acid Hyaluronic acid is a polysaccharide chain found throughout the body. It is a major component of joint tissue that helps to hold lubricating moisture in joints and cartilage, affecting their resilience, elasticity, and strength. BioCell Collagen II® is a patented hyaluronic acid, which has undergone an absorption enhancing hydrolyzation process that yields low molecular weight hyaluronic acid, chondroitin sulfate, and Collagen Type II peptides, unlike other preparations that have not been hydrolized. The low weight allows these compounds to deliver greater support for your joints. Glucosamine—An Amino Sugar Glucosamine is an amino sugar—a molecule made from an amino acid and a simple sugar. Amino sugars are the basis of virtually all connective tissues and lubricating fluids in the body. Just as amino acids are the building blocks of proteins, amino sugars are the building blocks of giant molecules called glycosaminoglycans (GAG’s), also known as proteoglycans and mucopolysaccharides. GAG’s are large, spongy, water-holding molecules that form the glue that holds us together. This substance is found in all connective tissue and mucous membranes. Numerous double-blind, placebo-controlled studies have examined the positive effects of oral administration of 1,500 mg of Glucosamine sulfate-the amount in one daily use of HYALURONIC JOINT COMPLEX. To ensure optimal absorption, this formula contains Glucosamine sulfate, N-acetyl Glucosamine and Glucosamine HCl. Chondroitin Sulfate Chondroitin sulfate is the most abundant GAG in the body. Its main role is in keeping cartilage fluid and elastic. It is found naturally in the body, where it is one of the critical compounds that makes up connective tissue. Connective tissue is responsible for building and supporting cartilage found in the joints and elsewhere. Dietary Sulfur for Joint Lubrication Both Glucosamine sulfate and chondroitin sulfate provide an additional source of sulfur, a mineral that is important for healthy connective tissue. HYALURONIC JOINT COMPLEX also features MSM, or methylsulfonylmethane, a naturally occurring form of organic sulfur found in body fluids and tissue, cow’s milk, plants and most natural foods. Sulfur may promote joint flexibility due to its role in supporting joint lubrication and movement. A double-blind, placebo-controlled study evaluated the effects of MSM with promising results. Supporting Ingredients for Joint Health: Manganese Ascorbate and Vitamin C Manganese is involved in the production of a wide variety of enzymes. These enzymes influence such biological processes as the production of collagen and the metabolism of protein and cholesterol. Manganese is also necessary for the growth and maintenance of tissues, cartilage and bones. The manganese ascorbate used in this formula also provides 55% vitamin C. Vitamin C is essential for the production and stability of collagen, the major protein in cartilage and connective tissue. It also protects cells from harmful free radicals. Innovative natural products, such as HYALURONIC JOINT COMPLEX, are an integral part of the Wellness Revolution. Taking personal responsibility for your health is at the heart of this revolution. Your local health food outlet is your source for nutritional education and advanced natural products. Source Naturals is pleased to partner with these outlets to bring you HYALURONIC JOINT COMPLEX—the next generation in joint formulas.
References:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=526) CHITOSAN: The Fiber that Binds Fat
Date:
June 25, 2005 07:55 PM
Overview Chitosan is a natural product that inhibits fat absorption. It has the potential to revolutionize the process of losing weight and by so doing, reduce the incidence of some of the most devastating Western diseases we face today. Chitosan is indigestable and non-absorbable. Fats bound to chitosan become nonabsorbable thereby negating their caloric value. Chitosan-bound fat leaves the intestinal tract having never entered the bloodstream. Chitosan is remarkable in that it has the abilty to absorb an average of 4 to 5 times its weight in fat.60 The same features that allow chitosan to bind fats endow it with many other valuable properties that work to promote health and prevent disease. Chitosan is a remarkable substance whose time has come.
Chitin, the precursor to Chitosan, was first discovered in mushrooms by the French professor Henri Braconnot in 1811.61 In the 1820’s chitin was also isolated from insects.62 Chitin is an extremely long chain of N-acetyl-D-glucoseamine
FIGURE 2. glucoseamine units. Chitin is the most abundant natural fiber next to cellulose and is similar to cellulose in many respects. The most abundant source of chitin is in the shells of shellfish such as crab and shrimp. The worldwide shellfish harvest is estimated to be able to supply 50,000 tons of chitin annually.63 The harvest in the United States alone could produce over 15,000 tons of chitin each year.64 Chitin has a wide range of uses but that is the subject of another book. Chitosan was discovered in 1859 by Professor C. Rouget.65 It is made by cooking chitin in alkali, much like the process for making natural soaps. After it
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---------------------------------- is cooked the links of the chitosan chain are made up of Glucosamine units. Each Glucosamine unit contains a free amino group. These groups can take on a positive charge which gives chitosan its amazing properties. The stucture of chitosan is represented schematically in Figure 2. Research on the uses of chitin and Chitosan flourished in the 1930s and early 1940s but the rise of synthetic fibers, like the rise of synthetic medicines, overshadowed the interest in natural products. Interest in natural products, including chitin and chitosan, gained a resurgence in the 1970s and has continued to expand ever since. Uses of Chit osan Some of Chitosan's major uses—both Industrial and Health and Nutritional—are listed in Tables 5 and 6. Water Purification Chitosan has been used for about three decades in water purification processes. 67 When chitosan is spread over oil spills it holds the oil mass together making it easier to clean up the spill. Water purification plants throughout the world use chitosan to remove oils, grease, heavy metals, and fine particulate matter that cause turbidity in waste water streams. Fat Binding/ Weight Loss Like some plant fibers, chitosan is not digestible; therefore it has no caloric value. No matter how much chitosan you ingest, its calorie count remains at
------------------------------ fibers, chitosan’s unique properties give it the ability to significantly bind fat, acting like a “fat sponge” in the digestive tract. Table 7 shows a comparison of chitosan and other natural fibers and their ability to inhibit fat absorption. Under optimal conditions, Chitosan can bind an average of 4 to 5 times its weight with all the lipid aggregates tested.60 (NOTE: This assessment was made without the addition of ascorbic acid which potentiates this action even further.77 Studies in Helsinki have shown that individuals taking chitosan lost an average of 8 percent of their body weight in a 4-week period.76 Chitosan has increased oil-holding capacity over other fibers.108 Among the abundant natural fibers, chitosan is unique. This uniqueness is a result of chitosan’s amino groups which make it an acid absorbing (basic) fiber. Most natural fibers are neutral or acidic. Table 7 summarizes the in vivo effects in animals of various fibers on fecal lipid excretion. As can be seen from the results listed, ingestion of chitosan resulted in 5-10 times more fat excretion than any other fiber tested. D-Glucosamine, the building block of chitosan, is not able to increase fecal fat excretion. This is due to the fact that Glucosamine is about 97 percent absorbed while chitosan is nonabsorbable. Fats bound to Glucosamine would likely be readily absorbed along with the Glucosamine. Chitosan, on the other hand, is not absorbed and therefore fats bound to chitosan can not be absorbed. Cholesterol Control Chitosan has the very unique ability to lower LDL cholesterol (the bad kind) while boosting HDL cholesterol (the good kind).78 Laboratory tests performed on rats showed that “chitosan depresses serum and liver cholesterol levels in cholesterol- fed rats without affecting performance, organ weight or the nature of the feces.”79 Japanese researchers have concluded that Chitosan “appears to be an effective hypocholesterolemic agent.”80 In other words, it can effectively lower blood serum cholesterol levels with no apparent side effects. A study reported in the American Journal of Clinical Nutrition found that Chitosan is as effective in mammals as cholestryramine (a cholesterol lowering drug) in controlling blood serum cholesterol without the deleterious side effects typical of cholestryramine. 81 Chitosan decreased blood cholesterol levels by 66.2 percent.82 It effectively lowered cholesterol absorption more than guar gum or cellulose.83 Laboratory test results indicated that a 7.5% chitosan formula maintained adequate cholesterol levels in rats, despite a dramatic increase in the intake of cholesterol. 84
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=501) The Flex Factor
Date:
June 11, 2005 05:18 PM
The Flex Factor by Thomas Dunville Energy Times, February 10, 2004 Arthritis, according to recent research, presents its sufferers with a Catch-22: The nagging pain of this condition can send your spirits plummeting. But, then, the depression spurred by the disconsolate persistence of arthritic pain can make the condition worse. Part of the trick is not to give in. If you can keep a bright mood even as your joints start to ache, the pain may lessen. While nobody can offer a guaranteed, 100% effective cure for arthritis, you don't have to be a passive victim. Exercise, the proper nutrients and a positive, can-do attitude can ease arthritis pain so effectively that scientists have been able to measure the difference. While medical researchers recognize the existence of over 100 types of arthritis, most people with achy joints suffer from osteoarthritis, which is caused by everyday wear and is found in just about everyone over age 60. When this condition occurs, the body's cushioning, its cartilage, thins and the inner surfaces of joints grind together painfully. Although aging itself increases your chances of enduring achy joints, other factors can also put you in the way of osteoarthritis. If you carry too much weight, it can wear on your joints. In addition, suffering a joint injury when you're young can increase your risk of developing osteoarthritis as you age. In another prevalent form of joint pain, rheumatoid arthritis (RA), the body's immune system mistakenly attacks the membranes lining the joints, causing swelling and pain. About 2 million Americans suffer from RA, which affects women about twice as often as men. Exercise Away Arthritic Woes Weekend warriors, don't despair! Arthritis doesn't have to mean the end of your weekend athletic wars. Matter of fact, in many cases, experts now recommend exercise to reduce the effects of arthritis. While that might sound counterintuitive, a study out of the Netherlands shows that folks in the early stages of rheumatoid arthritis who work out twice a week for about an hour each session may enjoy better physical and mental health than couch potatoes who receive physical therapy. The Dutch study took 150 people, many of whom had just started to suffer from rheumatism, and enrolled them in RAPIT, an acronym for Rheumatoid Arthritis Patients in Training. Rather than letting these folks rest their inflamed joints, twice a week the research team took them to the gym where they did:
When the researchers compared the physical changes in these arthritis sufferers with 150 others with similar arthritis complaints who underwent physical therapy without organized physical activity, they found that after two years the exercisers had benefited greatly. They were stronger and more aerobically fit, could perform everyday tasks more effectively and possessed a better, more optimistic mental attitude (Arthritis and Rheumatism 2003; 48(9):2415-24). However, the exercisers who were already suffering severe rheumatoid arthritis did experience some extra joint damage, so the researchers believe this kind of program is better for those in the early stages of the disease. " This study demonstrates that participation in long-term high-intensity exercise classes decreases the level of psychological distress in RA patients," says researcher Zuzana de Jong, MD, a professor at the Leiden University Medical Center in the Netherlands. Fish Oil Lowers Arthritis Risk Fish oil-in particular, cod liver oil-may be able to help ease osteoarthritis. In looking at the effects of fish oil, researchers at Cardiff, Wales, discovered indications that "...the omega-3 fatty acids in cod liver oil can reduce cartilage degradation and inflammation in arthritic disease," according to Bruce Caterson, PhD, one of the scientists involved. Dr. Caterson adds, "Our most recent work shows that by exposing human osteoarthritic cartilage to cod liver oil in the laboratory for just 24 hours we can turn off, or reverse, the action of the degradative enzymes and inflammatory factors affecting the tissue." John Harwood, PhD, another member of the Cardiff research team, adds, "This is where science and old wives' tales coincide. Our findings are consistent with advice that taking cod liver oil in early adulthood could prevent the onset of osteoarthritis and would reduce the harmful symptoms associated with the disease." Dr. Caterson further explains that the omega-3 fatty acids in cod liver oil inhibit enzymes that break down aggrecan and collagen, substances that cushion joints. Consequently, cartilage stays healthier, inflammation is lessened and arthritic pain decreases. The anti-inflammatory action of omega-3s in fighting rheumatoid arthritis is also supported by studies performed in the US (Am J Clin Nutr 2000; 71(1 Suppl):349S-51S). Other research shows that if you take natural vitamin E along with fish oil, you may improve even further your odds of relieving arthritis or lessening its effects (JACN 10/30/00). Glucosamine Repair Glucosamine, the stuff that cartilage is made from, has been shown to lower the risk of arthritis and possibly relieve its pain. This natural substance, made from a sugar and a molecule called an amine, is a building block of joint tissue. As a result, experts believe, when you take it in supplemental form, the body may use it to repair joints that have been damaged by arthritis. For instance, an investigation of osteoarthritis of the knee performed at the University of Liege in Belgium showed that taking Glucosamine could stop joints from deteriorating. The study, which involved more than 200 people suffering from osteoarthritis, found that in three years of taking Glucosamine supplements, many arthritis sufferers found that their condition actually improved (Lancet 2001 Jan 27; 357). Other Arthritis Fighters Chondroitin sulfate is another material that goes into the making of cartilage. Chondroitin helps cartilage stay hydrated and permits the flow of nutrients through the joint tissues. In addition, researchers believe that chondroitin helps fight inflammation, which can otherwise cause pain and stiffness as well as joint destruction. Taken together with Glucosamine, chondroitin is believed to hasten the healing of bone and cartilage. Another substance that may help ease the ache of arthritis is methylsulfonylmethane (MSM), a naturally occurring sulfur-bearing compound. "MSM appears to have anti-inflammatory effects when administered orally, intravenously or topically," says MSM researcher Stanley Jacob, MD, FACS, of the Oregon Health & Science University. That means it has shown an ability to reduce the heat, pain and swelling associated with arthritic conditions. MSM may also be able to reduce muscle spasms around joints and reduce the formation of scar tissue. Herbal Aid Herbal medicine has long been used by folks with achy joints. The yellow spice turmeric (Curcuma longa), a staple of Indian cooking, is a traditional Indian remedy for arthritis because of its painkilling properties. Ginger (Zingiber officinale), another culinary favorite, restrains the production of inflammatory chemicals called cytokines. And willow bark (Salix sp), the source of aspirin, is longer-acting and doesn't irritate the stomach lining. Those who suffer arthritis know that its pain and discomfort are often no laughing matter. But if you don't take arthritis lying down and manage to keep a smile on your face-and avail yourself of nature's remedies-you can get the upper hand on this often debilitating condition.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=296) Fighting Arthritis Naturally
Date:
June 10, 2005 02:16 PM
Fighting Arthritis Naturally by Donna Lee Nardo Energy Times, January 8, 2002 The annoying pain of arthritis grows ever more annoying: one of every six Americans, 43 million people, suffer arthritis, the leading cause of disability in the US. No pharmaceutical can reliably cure arthritis or slow its progression without possibly causing side effects. But you can help heal your hurting joints with nutrients and other natural substances. Every move you make hinges on healthy joints. The hinge joints in your fingers, knees and elbows swing back and forth. Ball and socket joints in our hips and shoulders twist and turn our arms and legs. But when arthritis attacks, joint function narrows, causing pain, stiffness, swelling and inflammation. While scientists search for the root cause of arthritis, they recognize that aging, injuries, allergies, a genetic tendency toward arthritis and being overweight all contribute to your risk. Researcher have identified more than 100 types of arthritis, including osteoarthritis (OA), rheumatoid arthritis (RA), gout, lupus, scleroderma, vasculitis, myositis, infectious arthritis, degenerative joint disease and spondylitis. OA and RA represent two of the most common arthritis forms. OA generally attacks the finger joints and larger joints like the hips and knees. Cartilage lining the joint deteriorates, often as a by-product of aging, but this deterioration can happen at any age. Sprains, fractures and repetitive injuries can increase your chances of osteoarthritis. Rheumatoid arthritis occurs when joints become inflamed and your immune system apparently releases antibodies in response to allergens. This type of arthritis can destroy and immobilize joints. Traditionally, doctors have treated arthritis with acetaminophen, aspirin and other drugs called non-steroidal anti-inflammatory drugs (NSAIDs). However, NSAIDs often offer only short-term relief. They can cause bleeding problems and ulcers. And while they may slow inflammation and pain, they also do nothing to repair damaged joints. A 1995 Journal of Rheumatology article also warned that prolonged NSAID use actually furthers deterioration of the joints (Oct/95; 22 (10):1941-6). Glucosamine at Work Scientists believe that injuries and aging deplete the body's supply of Glucosamine, a natural substance that forms, maintains and repairs joint cartilage. Glucosamine supplements are thought to replenish the supply and are prescribed for arthritis therapy in many countries. Several studies indicate that Glucosamine tackles pain and inflammation as effectively as NSAIDs without the side effects. It also helps rebuild arthritic joints. Research supporting Glucosamine's benefits abounds in Europe and Asia. One study suggests that Glucosamine sulfate supplements relieve pain as well as the NSAID ibuprofen (Osteoarthritis and Cartilage 1994; 2 (1):61-9). A recent Belgian study testing the effectiveness of Glucosamine on patients with OA of the knee captured the attention of the American medical profession. Results suggest that Glucosamine promotes physical changes in joints that halt the progression of OA (Lancet 2001, Jan 27; 357 (9252):251-56). After analyzing data from scores of clinical trials, the National Institutes of Health (NIH) saw enough promise in Glucosamine to launch its own multi-year study. Healing Spice Scientists have been testing the orange-yellow herb turmeric and have found that it may ease arthritis discomfort. Long a staple in the medical practices of Asia, turmeric has anti-inflammatory and antioxidant properties that reduce swelling and pain associated with arthritis. Researchers think this spice, used in such Indian cuisine as curry, may work more effectively than cortisone and other drugs that reduce inflammation. Ellen Kamhi, PhD, RN, and co-author of Arthritis: An Alternative Medicine Definitive Guide, considers turmeric an important therapy for arthritis. "Turmeric is quite effective, and it's much safer than conventional drug anti-inflammatories, with far fewer possible adverse effects," says Dr. Kamhi, clinical instructor at the State University of New York-Stony Brook Medical School. One study on people with RA demonstrated that the natural benefits of turmeric equaled those provided by a popular prescription drug known to cause side effects (Indian J Med Res 1980; 71:632-4). Another trial, published in the Journal of Ethnopharmacology, found that turmeric possesses unique anti-inflammatory properties (1993; 38:113-119). A trial published in 1994 also found that turmeric acts as an antioxidant to help protect joints (J Pharm Pharmacol; 46:1013-16). Aging Joints As we age, our bodies require more antioxidants to fight off damage caused by destructive molecules known as free radicals. Researchers believe that antioxidant nutrients can afford arthritis protection. A 10-year study evaluating the effect of vitamins C and E on the joints concluded that both nutrients protect against cartilage deterioration (Arthritis & Rheumatism 1996, April; 39 (4):648-56). According to Dr. Kamhi, "Arthritis is a lifestyle disease (and) no one remedy, either natural or pharmaceutical, will heal or reverse the arthritic process. Organic foods, exercise, stress reduction, and supplements can lead to a marked decrease in all arthritis symptoms with minimal side effects and enhanced overall health and wellness." While arthritis often makes sufferers limit their activity, experts agree that a sedentary lifestyle only exacerbates problem joints and that exercise maintains your range of motion. The type of activity recommended for each particular form of arthritis differs: for osteoarthritis, specific exercises like stretching and moving arthritic joints can help if more strenuous exercise forms are not possible. Rheumatoid sufferers need to use extra caution to prevent inflammatory flare-ups by balancing gentle exercise with rest. In any case, keep moving: performing household chores or spending time on your hobbies will profit painful joints. Weight Control In many cases of arthritis, maintaining an appropriate weight is critical. Surplus weight places extra stress on joints and accelerates cartilage deterioration. And don't be discouraged if your mainstream doctor pooh-poohs complementary arthritis control. "Any practitioner who categorically dismisses the use of all-natural therapies," advises Dr. Kamhi, "is not keeping up with reading current medical literature."
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=265) Inflama Rest - Natural COX-2 Inhibitor for Joint Comfort
Date:
June 02, 2005 12:37 PM
It happens. You reach for something and feel a sudden discomfort. Your joints and muscles may feel tender from overuse. Inside, your cellular systems are out of alignment, resulting in lessened mobility. Source Naturals understands how difficult joint discomfort can be to live with. We are deeply committed to developing well-researched formulas that address the root cause of joint distress. Our Bio-Aligned Formulas™ bring alignment to multiple interdependent body systems. Only this type of indepth formulation can provide the long-term relief you are looking for. Regain your comfort with Source Naturals INFLAMA-REST. Unlike many products that contain just a few ingredients to offer temporary relief, INFLAMA-REST is a Bio-Aligned Formula™, scientifically designed to address aches. INFLAMA-REST goes deep to the underlying cause of joint discomfort. These systems include: inhibition of pathways involved in joint discomfort, joint and muscle function, DNA protection and antioxidant defense. Addressing Joint Comfort on a Deep Cellular Level Discomfort can come from many places. From your head to your toes there are many tissues that can become uncomfortable from everyday use. Joint discomfort starts when stress, such as tissue damage, causes an imbalance of the biochemical pathways on a deep cellular level. The body has its own “innate intelligence” encompassing more than just the thoughts in the brain. It consists of ongoing and complex chemical reactions regulated by a wide variety of enzymes and chemical messengers. These reactions can sometimes get out of balance – but you can control and inhibit key body chemicals that would otherwise lead to cellular irritation. For example, certain types of prostaglandins that regulate normal physiological functions such as blood flow, are maintained at low levels in all our cells under everyday conditions. In response to stress, a message is sent to the outer membranes of certain cells to convert their fatty acids into arachidonic acid, the raw material for prostaglandins. This stress also directs cells to produce Cyclooxygenase enzyme- 2 or COX-2. This enzyme converts arachidonic acid into Prostaglandin E2, a particular type of prostaglandin specifically responsible for irritation on a cellular level. The result: joint discomfort. But that doesn’t have to happen. By supporting inhibition of the culprit COX-2, you can decrease Prostaglandin E2 production to bring your joint tissues back into a healthy and comfortable balance. INFLAMA-REST includes herbs that support inhibition of COX-2 in a variety of pathways. Ginger, turmeric and green tea all support direct COX-2 inhibition. But there are other places in our biochemical communication system where COX-2 production can be inhibited. Two additional factors that lead to COX-2 production are nitric oxide and the enzyme that produces it, nitric oxide synthase (iNOS). Nitric oxide is a free radical associated with cell growth and regeneration, blood vessel elasticity and COX-2 enzyme production. Resveratrol, rosemary and turmeric support iNOS inhibition, thus inhibiting your body’s over-production of nitric oxide and the COX-2 enzyme. A related irritation factor is also one of the latest scientific discoveries in cellular health - Nuclear Factor kappa-B (NF-kappa-B). NF-kappa-B works at the DNA level – at the blueprints of cells. When activated, this factor controls the genes that regulate cell growth, differentiation and regeneration. And blocking this factor is also associated with inhibition of both COX-2 and iNOS enzymes. Stinging nettle, milk thistle and Chinese Skullcap all block unhealthy NF-kappa-B activation in your body and thereby help support COX-2 inhibition. Cytokine Inhibition Compounds called cytokines, or interleukins, can also stimulate biochemical pathways leading to joint discomfort. Cytokines are chemical messengers produced by the immune system to regulate defensive activity when they are stimulated. For example, cytokines are released by macrophages in response to stimuli such as tissue damage. This results in rapid escalation and amplification of cell number and response. Constant stress can shift this system out of balance, resulting in tissue discomfort. Bringing these compounds back into balance can preserve your short-term comfort and longterm health. INFLAMA-REST contains curcumin from the spice turmeric. Curcumin assists the body’s inhibition of cytokine activity to support reduced cellular irritation. And Bioperine®, which is derived from black peppercorns, is added to assist curcumin assimilation. Stress Response: Joints and Muscle Support Inhibition of chemical messengers involved in joint discomfort is just part of a Bio-Aligned strategy for relieving discomfort. Research has shown that emotional stress, particularly long-term, can directly affect the body and set in motion mechanisms that cause physical discomfort. Ashwaganda and Chinese Skullcap (S. baicalensis) are herbs that help modulate the body’s response to stress and may help ease aches and discomfort. Boswellia, ginger, quercetin, milk thistle, feverfew, Oregon grape root and bromelain (an enzyme found in pineapples) provide additional soothing relief to your cells and tissues. Essential nutrients are also vital to maintaining your joint comfort. The tocotrienol forms of vitamin E, along with selenium, protect cell membranes from lipid-based free radicals. Magnesium aids energy metabolism in muscles and can reduce tenderness as well as muscle spasms. Zinc is essential for normal cellular repair mechanisms such as wound healing and is important for the growth and maintenance of connective tissue. And manganese works to protect cells from oxidation and to build healthy connective tissue as well, an essential component of healthy joints and muscles. Protecting Your DNA To reduce cellular irritation, you need to protect the DNA in your cells. DNA is the blueprint for all of the molecules in the body. If your DNA is altered or damaged, then needed molecules may not be produced, leading to short-term and eventually long-term damage. Curcumin, from turmeric, has been shown in in-vitro studies to protect DNA against strand breakage. Quercetin has also been shown to directly protect DNA against strand breakage and base oxidation from free radicals and damaging chemicals, according to recent in-vitro research. Providing Powerful Antioxidant Cellular Protection Antioxidants are selfless bodyguards of your cells. They donate their own electrons to stabilize free radicals in your body. Thus, antioxidants absorb the damage that would have been done to your tissues. Some regulatory chemicals, such as Nitric oxide, are powerful free radicals and oxidants. Oxidants also activate NF-kappa-B. Tissues, lipids, proteins and DNA are extremely sensitive to oxidation. Quercetin, milk thistle, turmeric, ginger, rosemary, vitamin E and resveratrol are all antioxidants that help modulate the activity of these compounds as well as protect cells and tissues from damage. Plus, Superoxide Dismutase (SOD), one of the most important enzyme antioxidants found in your body, has been added in a new cutting-edge form. The vegetarian SOD used in INFLAMA-REST is attached to Gliadin, a wheat protein, that has demonstrated significantly better absorption than SOD alone. Six Lifestyle Strategies for Fewer Aches
Inhibition of COX-2: Turmeric, Ginger, Chinese Skullcap, Green Tea, Resveratrol, Boswellia, Silymarin, White Willow Inhibition of Cytokine Turmeric, Stinging Nettle, Feverfew Inhibition of Rosemary, Green Tea, Resveratrol, Turmeric, Quercetin, Chinese Skullcap NF-kappa-B Activation Silymarin, Chinese Skullcap, Stinging Nettle, Rosemary, Resveratrol Stress Response: Ashwaganda, Magnesium, Chinese Skullcap, Oregon Grape, Feverfew, White Willow DNA Protection Turmeric, Quercetin, Rosemary Antioxidant Defense Silymarin, SOD Gliadin, Turmeric, Rosemary, Tocotrienols, Resveratrol, Ginger, Selenium, Manganese, Zinc Prostaglandin & Leukotrine Synthesis Joint & Muscle Support Inhibition of Nitric Oxide Synthesis Production
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=158) GlucosaMend™ Tissue/Joint Repair Complex
Date:
June 02, 2005 11:19 AM
More than 40 million Americans experience joint discomfort. But exciting new research proves you can do something about it. Our health and well-being is inextricably linked to lifestyle choices: the right combination of exercise, weight training and supplementation can strengthen muscles and joint tissues to minimize stress and degradation. Targeted nutrition to the multiple body systems related to joint and connective tissue can help maintain flexibility and joint comfort. GLUCOSAMEND supports the musculoskeletal system with structural building blocks and tissue production cofactors, as well as aiding the body’s mechanisms for soothing relief and antioxidant defense. Bio-Aligned Formula™ GLUCOSAMEND is uniquely effective because it is a Bio-Aligned Formula. Source Naturals evaluates the underlying causes of system imbalances. Then we design formulas that provide targeted nutrition to bring your interrelated body systems back into balance. Musculoskeletal System—Structural Building Blocks Certain building blocks of joints and connective tissue can help maintain joint integrity and comfort. Glucosamine is a major constituent of glycosaminoglycans, which in turn form proteoglycans, molecules that hold and bind the water that lubricates joints, disperses stress and nourishes joint tissue. The amino acids proline and lysine are structural components of collagen and elastin, which give strength to connective tissue. GLUCOSAMEND contains Glucosamine sulfate, N-acetyl Glucosamine, proline and lysine. Musculoskeletal System—Tissue Production Cofactors Some micronutrients are necessary as cofactors in the production of connective tissue. For example, vitamin C and copper help form hydroxyproline and hydroxylysine, main constituents of collagen. A unique property of grape seed extract is its ability to form a bond between broken collagen fibers, helping to repair them and restore flexibility and strength to connective tissues and joints. GLUCOSAMEND provides vitamin C, zinc, manganese, copper, and grape seed extract to address these cofactors. Soothing Relief Mechanisms Some herbs and nutrients have the capacity to support the body’s natural mechanisms for increasing comfort. Boswellia, for example, is an herb with soothing properties, while vitamin B-6 helps to stabilize collagen and elastin. Additional herbs and nutrients, acting in conjunction with antioxidant protectors, support tissue comfort and health. GLUCOSAMEND contains Boswellia serrata, quercetin, copper, and vitamin B-6. Antioxidant Defense The health and integrity of joints and tissues—specifically of cell membranes— is supported by botanicals and nutrients that support the body’s natural antioxidant response. When tissues become damaged, the body mounts a repair process that ultimately generates free radicals. These free radicals can also break down healthy cells and tissues in the process, hence the need for antioxidants to neutralize and break the cycle. GLUCOSAMEND provides grape seed extract, vitamin C, zinc, selenium, copper, quercetin to neutralize free radicals. Lifestyle Tips for Healthy Joints: A Strategy for WellnessSM Healthy lifestyle habits should be part of your individual strategy for joint wellness. Source Naturals believes in a holistic approach to living. Not only can supplements bring balances to your individual body systems but certain lifestyle choices can also bio-align your health. Exercise Regularly: Regular physical activity helps lubricate cartilage, strengthens muscles around joints, and promotes weight control. An exercise program geared to joint health includes stretching, mild weight training, and low-impact aerobics. Watch Your Weight: Population-based studies, including the well-known Framingham study, have consistently shown a link between obesity and challenges to joint health. Excess weight causes pressure on joints, and can speed the rate at which cartilage wears down. Eat Healthy: To support healthy joints, increase your intake of omega-3 fatty acids from salmon, sardines, flax seeds or flax oil, avoid excess protein intake, and replace animal with plant proteins when possible. You should also eat lots of organically grown fruits and vegetables, limit saturated fat and eliminate hydrogenated oils. Rest and Relaxation: Regularly scheduled rest gives your body time to recover and rebuild, allowing you to make the most of your exercise program. It’s important to know when to slow down. Supplementation: Source Naturals offers a range of products that can supplement your strategy for joint wellness. These include the pineapple enzyme BROMELAIN; SAME, a natural compound formed from the amino acid methionine, which has been found to support joint comfort and mobility; and CHONDROITIN to promote water retention and elasticity in cartilage and inhibit enzymes that break down cartilage. Structural Building Blocks N-Acetyl Glucosamine, Glucosamine Sulfate, L-Lysine, L-Proline Tissue Production Cofactors Grape Seed, Copper, Manganese, Zinc, Vitamins A, B-6 and C, Niacinamide Soothing Relief Mechanisms Boswellia Serrata, Quercetin, Turmeric, Copper, Magnesium, Zinc, Vitamin C Antioxidant Defense Grape Seed, Quercetin, Manganese, Selenium, Zinc, Vitamins A, C and E
References
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=152) Glucosamine Chondroitin Complex with MSM - Protect your Joint tissue ...
Date:
June 02, 2005 10:39 AM
Source Naturals is proud to offer one of the first products in the health food market to combine today’s most popular joint support nutrients: Glucosamine sulfate, chondroitin sulfate and MSM. Glucosamine CHONDROITIN COMPLEX WITH MSM provides the same amounts of chondroitin and Glucosamine shown in recent research to support healthy joints, along with MSM, vitamin C, and molybdenum— for a more powerful product. Together, these ingredients promote joint, tendon and ligament flexibility and easy joint movement. Glucosamine and Chondroitin: Structural Support for Joints Glucosamine, which is synthesized in our bodies from glucose, is a major component of joint-soothing glycosaminoglycans (GAG’s). Chondroitin sulfate is the most abundant GAG in the body. GAG’s in turn form proteoglycans, molecules that hold and bind the water that is so important to lubricate joints, disperse stress and provide nourishment to joint tissue. Glucosamine sulfate has been found to be well-absorbed after oral administration. Numerous double-blind, placebo- controlled studies have examined the positive effects of oral administration of 1,500 mg of Glucosamine sulfate— the amount in one daily use of Glucosamine CHONDROITIN COMPLEX WITH MSM. Dietary Sulfur for Joint Lubrication Both Glucosamine sulfate and chondroitin sulfate provide an additional source of sulfur, a mineral that is important for healthy connective tissue. The formula also features MSM, or methylsulfonylmethane, a naturally occurring form of organic sulfur found in body fluids and tissue, cow’s milk, plants and most natural foods. MSM is an important source of dietary sulfur, which is vital to all tissues and needed constantly in an assimilable form. Sulfur may promote joint flexibility due to its role in supporting joint lubrication and movement. Molybdenum: Critical Trace Mineral Glucosamine CHONDROITIN COMPLEX WITH MSM also contains molybdenum, to ensure an adequate supply of this trace mineral to the body. High amounts of organic sulfur in the diet increase urinary molybdenum loss. Molybdenum is necessary for the proper functioning of the sulfite oxidase enzyme, which in turn supports the proper metabolism of Glucosamine sulfate and MSM. Vitamin C: Essential for Collagen Vitamin C is essential for the production and stability of collagen, the major protein in cartilage and connective tissue. It also protects cells from harmful free radicals. Unique Joint Formula Now you can enjoy the benefits of today’s hottest joint nutrients—Glucosamine, chondroitin and MSM—all in one formula. Glucosamine CHONDROITIN COMPLEX WITH MSM: the next generation in joint nutrition. Glucosamine CHONDROITIN COMPLEX WITH MSM is available in bottles of 30, 60 and 120 tablets.
References
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=150) Elan Vital - The Vital Essence of Life - Multi-Vitamin and Mineral Supplement
Date:
June 01, 2005 01:13 PM
What makes ÉLAN VITÀL unique is its unprecedented range of nutriments in high potencies and superior forms. Quite simply, it stands alone among multiples: a quantum leap beyond maintenance...into excellence. Not only does it offer unparalleled antioxidant nutrition and a full-spectrum of essential vitamins and minerals, ÉLAN VITÀL is also formulated with specific nutrients that support: Today’s inflated levels of stress and pollution give rise to harmful free radicals – unpaired electrons that can damage living cells and compromise the proper function of tissues and organs. Antioxidants serve to protect the body by neutralizing free radicals; in fact, many scientists believe that high levels of antioxidants may prolong the effective working life span of the body’s cells. The primary strategy of ÉLAN VITÀL is to provide a wide range of antioxidants at exceptional levels, from both botanical and biochemical sources. Plantioxidant Protection ÉLAN VITÀL has the powerful advantage of Plantioxidants™, standardized botanical extracts with unparalleled free radical-scavenging properties. Plantioxidants have the unique quality of providing targeted protection because they tend to be attracted to different organs in the body. Grape Seed extract is rich in potent proanthocyanidins, a special class of highly bioavailable, water-soluble bioflavonoids that have the unique ability to cross the blood-brain barrier where they support the health of brain cells. Proanthocyanidins have been shown to efficiently scavenge oxygen radicals, as well as optimize the transport of vitamin C. They also have an affinity for collagen and elastin, the structural proteins that are abundant in vessel linings and other connective tissue. ÉLAN VITÀL contains the most concentrated extract of Bilberry available, with at least 25% anthocyanosides – compounds which are similar to proanthocyanidins but with an unusually strong attraction to optical tissue. They have been shown to protect cellular integrity in the delicate structures of the eyes. Ginkgo biloba extract is a standardized concentration of prime quality ginkgo leaves, yielding 24% ginkgoflavoneglycosides. These active compounds are potent antioxidants that have been associated with superior oxygen transport throughout the body with a special affinity for brain capillaries. Silymarin is the name given to a complex of three bioflavonoid-like compounds — silybum, silycristin, and silymarin — extracted and concentrated from milk thistle seeds. Silymarin functions in the body as an antioxidant with a special attraction for the liver. It has been researched and used extensively in Europe, where it is prized for its unique ability to nourish the liver and support its natural regeneration process by speeding up DNA synthesis in liver cells. Quercetin is a bioflavonoid present in some foods, such as onions and blue-green algae. A cousin of rutin, quercetin has been shown to stabilize cell membranes and help prevent free radical damage to this vital but vulnerable part of cells. Bioflavonoids and related compounds do their best antioxidant work when in the presence of Vitamin C, the nutrient they are most often paired with in nature. The vitamin C provided in ÉLAN VITÀL is both water- and fat-soluble. This combination is crucial because the tissues and membranes richest in fatty acids are most at risk to free radical attack. Fat-soluble vitamin C in the form of ascorbyl palmitate has an affinity for these highly vulnerable structures. Antioxidant Nutrients ÉLAN VITÀL not only provides botanical defense plants to combat free radicals, but also contains tried-and-true antioxidant nutrients: Biochemicals known as vitamins, minerals, and amino acids work together for maximum protection to all the body’s cells. The amino acid, N-Acetyl Cysteine, is a powerful and highly versatile antioxidant that doubles as a precursor to glutathione and glutathione peroxidase, two of the most formidable cell-protective compounds manufactured by the body. Studies have shown that supplemental N-acetyl cysteine enhances internal levels of glutathione far better than supplements of glutathione itself. Methionine also contributes to the synthesis of glutathione, and is an efficient transporter of certain antioxidant minerals, magnifying their activity. Vitamin A is included in both its fat-soluble palmitate form and in its provitamin form, Beta Carotene. While preformed A has long been known to play a role in the body’s defenses, beta carotene itself has recently been shown to possess a powerful ability to scavenge free radicals and contribute to the youthful function of some tissues. Vitamin E is one of the most important antioxidant compounds in nature. It works to prevent harmful oxidation within each cell and is vital in the protection of red blood cells from free radical-induced rupture. Selenium is an extremely powerful antioxidant shown in studies to work synergistically with Vitamins A, C, and E. In combination with cysteine, selenium helps build the glutathione peroxidase molecule. ÉLAN VITÀL offers a 50/50 blend of the two most scientifically supported forms of selenium: L-selenomethionine and sodium selenite. In addition to being an antioxidant itself, Zinc works closely with fat-soluble vitamin A by facilitating its release from the liver to the rest of the body. In ÉLAN VITÀL, Zinc is synergistically bound to methionine for optimal bioavailability. Copper sebacate is a natural compound that can function as the copper-SOD antioxidant system in the body, one of the first lines of defense against free radical attack. Copper sebacate is a highly absorbable form that possesses significant free radical scavenging activity. Supporting Structural Integrity An important adjunct to antioxidant nutrition is the amino sugar N-Acetyl Glucosamine, or N-A-G™. Amino sugars are essential components of cell membranes and their surface structures, as well as of the “ground substance” that holds body tissues together. They are also a key constituent of the synovial fluid in the joints. Recent research has revealed that amino sugars play an important role in maintaining the integrity of the connective and structural tissues of the body, a property that complements perfectly the actions of antioxidants: where antioxidants may prevent damage from occurring, amino sugars may help the body repair and regenerate damaged tissue. N-A-G’s activity is supported in ÉLAN VITÀL by other nutrients helpful to structural tissue. The mineral Manganese is required for building amino sugars into mucopolysaccharides, the large molecules that make up the ground substance that holds cells together. Choline and Inositol are both components of phospholipids, principal constituents in cell membranes. Two B vitamins, Folic Acid and Vitamin B12, are important to cell regeneration and to the development of healthy red blood cells. Enhanced Energy to Maximize Metabolism ÉLAN VITÀL is a potent source of coenzymes, metalloenzymes, and metabolites involved in energy production in the body. There are two main energy production cycles in the cells: the glycolytic cycle and the Krebs’ cycle. Together, they generate about 90-95% of the body’s entire energy supply – using fats, sugars, and amino acids as fuel, with enzymes as facilitators. The enzymes which catalyze energy production function in combination with coenzymes made from vitamins such as B1, B2, B3, B5 and Biotin, plus metalloenzymes made from minerals, including Magnesium, Manganese, and Copper. Biotin, an often overlooked nutrient, may function to help the body maintain a youthful metabolism. The mineral Magnesium aids in energy production, not only by acting as a cofactor to some enzymes, but also as a stabilizer of ATP, the body’s primary energy molecule. Some of the key connecting enzymes in the energy production process require two additional non-vitamin coenzyme nutrients to maximally convert food into energy: Lipoic Acid and Coenzyme Q10. Lipoic acid helps convert the end-product of the glycolytic cycle, pyruvate, into acetyl-CoA, a principal fuel for the higher energy Krebs’ cycle. Coenzyme Q10. is the connecting link for three of the four main enzyme complexes in the Electron Transport System, an off-shoot of the Krebs’ cycle, where ATP molecules are “cashed in” for energy. The muscle-supporting electrolyte mineral Potassium is in the form of Alpha- Ketoglutarate, a critical Krebs’ cycle metabolite that has additional benefits. It has long been used to improve the efficiency of ammonia-clearance from the body, an indispensable function, as ammonia is both exceedingly harmful and constantly produced through the natural metabolism of proteins. Because alpha-ketoglutarate is an organic compound well-recognized by the cells, it is an excellent transporter of potassium into the cells. Succinic Acid, or succinate, is also a metabolite in the Krebs’ cycle. It not only boosts production of ATP energy potential, but also increases the muscle cells’ production of creatine phosphate, another high energy biochemical. Chromium is the essential mineral component of glucose tolerance factor, or GTF, which functions to help insulin (one of the two main blood sugar-controlling hormones in the body) draw sugar molecules from the bloodstream into the cells. Smart Nutrients ÉLAN VITÀL contains natural substances that sharpen performance beyond just the physical. N-Acetyl L-Tyrosine is a highly stable and absorbable form of the conditionally essential amino acid L-tyrosine, a precursor to the major excitatory neurotransmitters dopamine, norepinephrine, and epinephrine. DMAE is a precursor to one of the body’s main neurotransmitters, acetylcholine. From the Plantioxidants comes standardized Ginkgo biloba extract, whose compounds readily cross the blood-brain barrier where they support the integrity of the capillaries in the brain. Guarding the Liver ÉLAN VITÀL provides several nutrients which collectively support optimal liver function. This is an essential aspect of a multiple, because the liver is responsible for converting nutrients – from food as well as from supplements – into their usable forms. If liver function is compromised in any way, nutrient supplements may be rendered inert in the body. The liver is especially at risk because it must filter out ingested toxins and is continually exposed to chemicals that generate free radicals. N-Acetyl Cysteine and Silymarin have both demonstrated a strong affinity for the liver. Nacetyl cysteine contributes to increased levels of glutathione and glutathione peroxidase, both of which the liver uses in its natural cleansing function. Silymarin provides unparalleled support to the liver’s natural regeneration process. Because of its many vital functions, the liver uses as much as 12% of the body’s energy supply, even though it represents only 3% of body weight. The liver therefore uses a greater proportion of energy nutrients, especially Coenzyme Q10 and Lipoic Acid. Both are highly concentrated in the liver; and lipoic acid in particular has been researched and used heavily in Europe where it is prized for its special protective actions in the liver. Ascorbyl Palmitate is a fat-soluble form of Vitamin C, meaning it can provide antioxidant protection for fatty tissue. This is especially valuable to the liver, which tends to develop fatty streaks that are most vulnerable to damage. Vitamin E has been researched extensively for its antioxidant properties with regard to the liver. The Multiple for the 21st Century ÉLAN VITÀL is truly a one-of-a-kind multinutrient supplement: one that leaves no nutritional stone unturned. Based on the biochemical principles of nutrition and metabolism – in context of today’s challenges to our health – ÉLAN VITÀL approaches optimal nutrition from several directions...all leading to a lifetime of health and vitality.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=142) Study Says Supplements Could Save Billions in Health Care Costs 
Date:
May 09, 2005 05:52 PM
Study Says Supplements Could Save Billions in Health Care CostsA study released at a House subcommittee hearing in late September on the cost savings and health benefits of selected dietary supplements projected a $15 billion reduction in health care costs over a five-year period from calcium and folic acid. The study, commissioned by the Dietary Supplement Education Alliance (DSEA) and conducted by the Lewin Group, found that the five selected supplements—omega-3 fatty acids, Glucosamine, and saw palmetto along with calcium and folic acid—could make a significant impact on health care costs while positively affecting consumers’ health status. DSEA asked the Lewin Group to put a dollar figure on the benefits of calcium and folic acid because the Food and Drug Administration (FDA) allows health claims on products containing these nutrients. Since the study began, FDA also authorized qualified health claims on omega-3s, and the National Institutes of Health has implemented large-scale studies of saw palmetto and Glucosamine. “Many industry experts have long believed that dietary supplements provide consumers with long-term health benefits by reducing the incidence of debilitating health problems, and this study proves it,” said Elliott Balbert, president and CEO of Natrol, Inc. (Chatsworth, CA) and president of DSEA. “The findings provide evidence to support both the cost savings and quality-of-life benefits of these particular supplements.” DSEA commissioned the Lewin Group to critically review the research literature on the five supplements for consistency, validity, and impact (i.e., size of the effect; to develop estimates of the potential health care expenditure savings that could result from daily use of two of the supplements; and to suggest areas of future research for supplements where there is emerging evidence. The Lewin Group arrived at the $15 billion figure by focusing on two specific health issues: hip fractures (including hospital and nursing facility expenses) in the case of calcium along with vitamin D, and neural tube defects in the case of folic acid. Joan DaVonzo, vice president of the Lewin Group, said at a news teleconference following the Sept. 22 hearing that the savings in health care costs from supplementing calcium intake might be even larger than the projected $13.9 billion if other types of fractures were included. Dr. Jeffrey Blumberg, professor of nutrition at Tufts University and one of the witnesses who testified before the House Subcommittee on Human Rights & Wellness chaired by Rep. Dan Burton (R-IN), told reporters the health benefits—and potential cost savings—of folic acid supplementation went far beyond the $1.1 billion estimate for neural tube defects. He said folic acid has been shown to help prevent other types of birth defects as well as reducing the risk of cardiovascular disease and certain types of cancer. “It’s not a one nutrient/one disease relationship,” Blumberg said. “Research shows that the typical American diet does not always provide a sufficient level of nutrients. This study just reveals the tip of the iceberg in the ability of supplements to contribute to a healthier America,” said Elwood Richard, president and founder of supplement manufacturer NOW Foods (Bloomingdale, IL), in response to the study. DaVonzo acknowledged that the potential for the five supplements studied went beyond the dollar figures projected in the study. For instance, in the case of saw palmetto and its reported prostate health benefits, “The impact could be huge,” she said. “It’s no surprise to anyone in the industry that dietary supplements are safe, affordable, and effective, and this study not only confirms that statement, but will, more importantly, reach an audience well beyond industry,” said David Seckman, executive director and CEO of the National Nutritional Foods Association. “An even more critical finding is the fact that dietary supplements can dramatically cut health care costs if used regularly—a point that won’t be lost on any American consumer, the media, and lawmakers aware of the staggering—and rising—cost of health care in this country.” To help spread the message beyond the halls of Congress, DSEA prepared an audio news release and was organizing a satellite media tour. DSEA vice chairman Jon Benninger said the hope was to commission followup studies on other nutrients “as funding allows.” Vitamin Retailer Magazine, Inc., 431 Cranbury Road, East Brunswick, NJ 08816 //www.oprmagazine.com/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=17) | ||||||||||||
Glucosamine is formed in the body from glucose. This compound is found naturally occurring in the joints of the body. It is important as a precursor and stimulant of the construction of proteoglycan synthesis, which forms the basis of cartilage. Also, Glucosamine is important for the synthesis of substances that compose tendons, ligaments, the respiratory system, and the mucous membranes of the digestive and respiratory tracts. 
sulfate therapy helps to prevent joint destruction. Glucosamine sulfate is responsible for helping to heal, relieve pain, reduce inflammation, and improve damage to joint tissue, without causing the side effects that are often associated with drug therapy. 
