Active CoQ10

 

The benefits of Coenzyme Q10 have become increasingly well-known. This important nutrient has been shown in clinical trials to improve heart function, reduce the side effects of certain drugs used to treat cancer, and slow the progression of serious brain diseases such as Parkinson’s disease. Now research has opened a new chapter in the CoQ10 story, highlighting the benefits of ubiquinol, the active form of CoQ10, to increase energy and stamina, and reduce some of he physical signs of aging.

In this issue of Ask the Doctor we will review the benefits of Coenzyme Q10, and discuss the differences between CoQ10 and its active form –ubiquinol.

 

Q. What is CoQ10?

A. CoQ10 is a natural, fat-soluble nutrient present in virtually all cells. CoQ10 also is known as ubiquinone. That’s because CoQ10 is ubiquitious and exists everywhere there is life. CoQ10 is vital to adenosine triphosphate (ATP) production. ATP is the energy-rich compound used for all processes requiring energy in the body. Although CoQ10 is produced by the body and exists in some limited dietary sources, these levels may be insufficient to meet the body’s requirements. CoQ10 levels diminish with age and as a result of dietary inadequacies and various disease states. Also, some drugs, especially a group of cholesterol lowering prescription drugs known as “statins,” (Pravachol, Zocor, Lipitor, etc.) significantly reduce CoQ10 levels in the body.

 

Q. What is ubiquinol? Is it the same or different from CoQ10?

A. Ubiquinol and CoQ10 are very closely related. Ubiquinone, or CoQ10, is the oxidized form of the molecule. This means it has to be converted to a non-oxidized form before it can perform its work. Ubiquinol is the active form of this nutrient. Our bodies convert CoQ10 to ubiquinol – which is the form needed to produce cellular energy. Until recently, it was not possible to use ubiquinol as a supplement because it is very unstable outside the human body. But research has now found a way to keep this molecule stable so it can be successfully taken in supplement form.

 

Q. If CoQ10 gets converted to ubiquinol anyway, can’t I just take CoQ10?

A. While it is true that our bodies can convert CoQ10 to ubiquinol, it isn’t true that we all do this equally well. In fact, as we age, our ability to convert CoQ10 to ubiquinol declines. And some people even have a gene that makes them less effective at this conversion than the majority of the population. IN fact, several common health issues have been associated with less than optimal ratios of CoQ10 to QH. For healthy people the ideal ratio is approximately 97% Ubiquinol to 3% CoQ10. But in people with diabetes, for example, the ratios have been found to range from 43% ubiquinol to 47% CoQ10 in mild diabetes, to only 24% ubiquinol to 76% CoQ10 in severe diabetes. These numbers are for men; the numbers for women vary by 2 to 5 percentage points.

So for older folks, the 30-50% of people who have the gene that impairs CoQ10 conversion, or for people who have serious health concerns, supplementing with ubiquinol instead of CoQ10 might be the smart choice.

 

Q. What are the health benefits of CoQ10 and Ubiquinol?

A. There have been many studies showing that CoQ10 is beneficial in treating and preventing heart disease and conditions such as high blood pressure atherosclerosis (hardening of the arteries), angina, and congestive heart failure (CHF). It’s been shown that heart attacks tend to occur when CoQ10 levels are low in the body. Exciting new research has found that CoQ10 in a unique delivery system supplementation may slow the progression of symptoms associated with neurological diseases such as Parkinson’s disease, ALS, Huntington’s disease and Alzheimer’s disease.

In addition, CoQ10 is beneficial for diabetes, immune dysfunction, cancer, periodontal disease, prostate cancer, and neurological disease. While the research on ubiquinol is still very new, it is reasonable to expect that its benefits will be equal to or perhaps even better than CoQ10, because it is the more active form.

 

Q. Why is CoQ10 especially important for preventing and treating heart disease, and for neurological diseases like Parkinson’s disease?

A. The heart and brain are some of the most metabolically active tissues in the body. Both require large amounts of uninterrupted energy, which means these tissues also need increased amounts of ubiquinol. Research has shown that many people with heart of brain diseases have serum CoQ10 levels that are lower than those of healthy people. Correcting such deficiencies often can produce significant results. However, these diseases become more common as we age – right at the time our ability to convert CoQ10 to its active form, ubiquinol, declines.

 

Q. How might ubiquinol be important for the heart?

A. Heart Health: A study on patients admitted to the hospital with an acute myocardial infarction (AMI) found that CoQ10 can provide rapid protective effects in patients with a heart attack if administered within three days of the onset of symptoms. Seventy-three patients received CoQ10 (120 mg/d). The study’s control group consisted of 71 similarly matched patients with acute AMI. After treatment, angina pectoris (severe chest pain signifying interrupted blood flow to the heart), total arrhythmias (dangerously irregular heartbeats), and poor function in the left ventricle (the essential chamber of the heart) were significantly reduced in the CoQ10 group compared to the placebo group. Total deaths due to sudden cardiac failure and nonfatal heart attacks also were significantly reduced in the CoQ10 group compared with the placebo group.

In another study, CoQ10 was studied in 109 patients with high blood pressure (hypertension). The patients were given varying doses of supplemental CoQ10 with the goal of attaining a certain blood level (greater than 2.0 mcg/l). Most patients were on medications to treat hypertension. Half the patients were able to stop taking some or all of their prescription drugs at an average of 4.4 months after starting CoQ10. The 9.4% of patients who had echocardiograms, performed both before and during treatment, experienced a highly significant improvement in heart wall thickness and function. This improvement was directly attributed to CoQ10 supplementation.

Congestive heart failure (CHF) is a debilitating disease that affects 5 million people in the U.S. It causes edema, difficult breathing, and impaired circulation. In another study, CoQ10 restored healthy heart function in CHF patients. Patients received 100 mg of CoQ10 or a placebo twice daily for 12 weeks. Before and after the treatment period, the investigators introduced a catheter into the right ventricle of patients’ hearts to determine the degree of CHF damage to the heart muscle. The patients’ heart muscles at rest and work improved significantly. The researchers concluded CHF patients would greatly benefit from adjunctive CoQ10 treatment. Since ubiquinol is the active form of CoQ10, it may be able to overcome the hurdles to providing maximum impact, most importantly, age and genetic related inefficiencies in converting CoQ10 to active CoQ10 (Ubiquinol).

 

And Neurological Health?: A study sponsored by the National Institutes of Health showed that supplementing with CoQ10 in a unique delivery system was associated with a slowing of the progression of Parkinson’s disease. Participants were divided into 4 groups and their physical skills (coordination, walking, etc) and mental skills were evaluated. Each group then received 300 mg, 600 mg, or 1200 mg of a special form of chewable CoQ10, or a placebo. The researchers evaluated the participants after 1, 4,8, 12, and 16 months of treatment. Each participant was again scored on motor, mental, and activities of daily living skills.

The results of the study showed that the people who took the highest dosage of CoQ10-1200 mg-experienced the least decline in their physical abilities. The results were so encouraging that the researchers will be continuing with new studies, suing higher dosages to see if the results can get even better.

Huntington’s disease (HD) is a devastating and degenerative inherited disease that is always fatal. In fact, no other medication, drug, or nutritional supplement has ever been shown to cause a decline in the progression of this terrible disease. A study compared CoQ10 against remacemide (an investigational HD drug made by AstraZeneca Pharmaceuticals), in 347 HD patients who were in the early stages of the disease. Remacemide blocks glutamate, the neurotransmitter scientists think may cause the death of brain cells that occurs in Huntington’s disease. While remacemide had no effect on the progression of HD, CoQ10 showed a trend toward slowing the disease by an average of 15%. This meant the HD group taking CoQ10 was able to handle every day activities of life a little longer than the patients taking remacemide or a placebo. They also were able to focus their attention better, were less depressed, and less irritable.

The 15% slowing of decline can result in about one more year of independence of HD patients. Needless to say, the gift of an additional year of health in the lives of HD patients is incredibly significant.

Because of these impressive results, researchers are hopeful that supplemental CoQ10 will have beneficial effects for people with other neurological diseases such as ALS and Alzheimer’s disease, too. Studies are under way to confirm these effects.

Using the active form of CoQ10 helps to assure that, regardless of age or illness, the CoQ10 can have the greatest impact.

 

Q. What have been the results of research studies with Ubiquinol?

A. One of the most interesting effects of Ubiquinol that has been reported so far is its ability to slow the physical signs of aging. In laboratory studies, administration of stable ubiquinol to mice forestalled the changes associated with aging – rounded spine, patchy fur and irritated eyes. While the mice who received ubiquinol did not necessarily live longer than the mice that didn’t, they lived better. But it is important to note that these mice were bred to die at a young age. Human studies are needed to determined true impact on longevity.

Additionally, supplemental, stable ubiquinol has been shown to increase physical energy and stamina. In an animal study, the length of time rats were able to run on a treadmill before getting tired was measured. The same rats were then given ubiquinol and the treadmill test was repeated. The length of time the rats were able to run before tiring increased 150 times.

 

Q. How can one supplement have applications for neurological diseases, heart health, and even the immune system?

A. Supplements often have more than one function, especially when it’s a substance like CoQ10, which is present in all parts of the body. All nucleated cells (most cells other than red blood cells) have mitochondria and all cells require energy to function. CoQ10 is vital to ATP production. Thus, CoQ10 has applications not only in neurological (neurons or nervous system cells) and cardiac health (myocardium or heart tissue), but also for the immune system.

 

Q. Should I take CoQ10 or ubiquinol? How much should I take?

A. While everyone can benefit from CoQ10 or ubiquinol supplementation, it appears that ubiquinol should be the first choice for older adults, people with known genetic inefficiencies in converting CoQ10 to ubiquinol, and for people with serious heart disease or neurological diseases such as Parkinson’s disease, who are otherwise supplementing with high levels of CoQ10. For people in overall good health, a high quality CoQ10 supplement with proven absorption is a good choice.

Take 200 to 300 mg of CoQ10 or 100 mg ubiquinol daily, depending on your health history. The safety of both forms has been tested, and no significant side effects reported. Occasional mild stomach upset may occur. Taking your CoQ10 or ubiquinol with meals usually alleviates this rare effect.

 

Conclusion
CoQ10 is not the only answer to the complex issues of heart disease, neurological diseases, or immune dysfunction; however, research indicates that it’s a bigger piece of the puzzle than physicians and scientists ever imagines. The more we study this naturally occurring compound, the more benefits we find. And with this new ability to provide CoQ10 in its active form, ubiquinol, for the first time, even greater benefits may be derived.

Supplements for Children

 

While most parents try hard to make nutritious meals for their family, most children find the appeal of refined, fast, and junk food simply overwhelming. And, sadly, increasingly easy to buy and consume, as well. From kindergarten through 12^th grade, in both grade schools and high schools, vending machines offer calorie laden candy bars, sugar-filled soft drinks, and snack foods loaded with fat and salt. Many school cafeterias actually sell fast-food to children for lunch every day. In fact, it seems almost everywhere children go and gather, visually enticing but nutritionally lacking snacks and soft drinks are sure to be available.

Determined to counteract this disturbing trend, parents everywhere are urgently seeking solutions to help their children get the nutrition they need. One answer is supplemental multivitamins. There are certainly plenty of multivitamins formulated for children currently on the market. However, these products vary considerably in quality and content. Some lack certain vital nutrients. Some taste terrible. Still others are loaded with sugar and artificial flavorings. The good news is that there are superior multivitamins and exceptional immune boosting products formulated specifically for children that actually taste great. In this issue of Ask the Doctor, we will discuss childhood nutrition and how to help ensure your children’s health with high quality, 100% natural flavored nutritional supplements.

 

Q. Do children really benefit from vitamin supplements? Can’t I make sure they get the vitamins and minerals they need from meals?

A. Even the most nutritionally vigilant parent cannot be 100% certain what nutrients are in the food they serve their children. That’s because there’s so much variability in the food we prepare. For instance, fat-soluble vitamins can withstand normal cooking, but vitamins A and E are gradually destroyed by exposure to air. Water-soluble vitamins such as B1, B6, folic acid, and pantothenic acid are destroyed by heat. Vitamin B2 is destroyed by light and heat, while light and air destroy vitamin C. Certain food preservatives and preparation methods also destroy the vitamins in food. To further complicate matters, some fruit and vegetables are grown and harvested in such a way that does not promote nutrient content – so even raw foods may be lacking.

Then there are those crazy food phases all children seemingly go through. While these phases are generally harmless in the long run, a recent alarming exception was in the news. A five-year old boy ate nothing but cheese pizza, Pop-tarts, biscuits, and water, refusing fruits, vegetables, juices and vitamins. He slowly developed limp, swollen gums, and small purple spots appeared on his skin. After five months of this extremely deficient diet, he was unable to walk or get out of bed because the pain was so severe. Doctors diagnosed the boy as having a severe vitamin C deficiency after ruling out other ailments such as leukemia. Within a week of getting vitamin C supplements, the boy’s pain and other symptoms were completely resolved. Obviously, this little boy’s story is unusual. However, even mild food phases (such as “If It’s Green It Must Be Yucky” or “The Only Good Crust Is A Cut-Off Crust”) can result in awfully lop-sided nutrition.

 

Q. Can multivitamins help my child’s performance in school?

A. Most teachers firmly believe that nutrition and learning go hand in hand. They are convinced that children who are well nourished possess the mental stamina that’s needed to learn and retain even difficult concepts. But can multivitamins help children become better students?

Two independent research teams recently conducted randomized trials to find the answer. The researchers followed 245 school-children aged 6 to 12 years for three months. They gave half of the children multivitamin tablets every day, and half of the children placebos. When the children were tested, the children in the multivitamins group showed an increase in their nonverbal intelligence scores. Nonverbal intelligence is closely associated with academic performance.

 

Q. I can’t get my children to take 100% natural flavored multivitamins because they don’t taste very appealing. Isn’t there some way to make a 100% natural multivitamin taste good enough for my children to willingly take?

A. Yes, there is! Because most children need chewable multivitamins, manufacturers need to contend with the truly terrible taste of certain minerals. Magnesium, iodine, copper, and iron are probably the worst tasting. Some solve this dilemma by skimping on the amounts of these minerals in their children’s formulas. Others cover up the bad taste with either massive amounts of sugar or artificial flavors, or both.

However, a select few multivitamin makers have discovered how to offer a natural flavored, great tasting children’s multivitamin that contains these vital minerals. The best children’s vitamins are prepared in a base of natural fruit that provides both antioxidants and other healthy phytonutrients. Children’s multivitamins made in such a fruit base have very low sugar content, as well, providing as little as four calories a day. Fructose – fruit sugar – is the preferred sweetening agent, in addition to the fruit content.

 

Q. What vitamins should be in a multivitamin for children?

A. There are several vitamins and minerals that children need to take each and every day. They include biotin, folate, niacin, pantothenic acid, vitamins B12, B1, A, B6, C, D, E, and K. Let’s review a few. We’ll start with folate, one of the B vitamins. This vital vitamin helps the body use protein, helps make DNA, helps cells grow and divide, and keeps the nervous system healthy. In fact, folate is so important to children that the Food and Drug Administration (FDA) mandated that folate must be added to many foods most children eat daily. Since 1998, cereal, enriched bread, flour corn meal, rice, and pasta have been folate-fortified with this B vitamin.

One of folate’s vital actions is the reduction of homocysteine levels in the blood. Homocysteine is an amino acid (the building block of protein) that is normally produced in the human body. Research has shown that high levels of homocysteine can irritate blood vessels, make blood clot more easily than it should, and cause blockages in arteries increasing the risk of heart attacks and strokes .

However, study after study has proven that taking folate reduces harmful homocysteine levels. While most of this research has been in adults, a recent study looked at children’s homocysteine levels. Researchers examined over 3500 children and discovered that high homocysteine levels increased the risk for heart disease in these children, especially as they grow. The researchers leading this study reinforced how critical folate is for all children.

Other critical vitamins for children are the vitamins C and E. The rates of childhood asthma have increased significantly here in the US. There seem to be several reasons for this troubling trend, including environmental pollution and changes in the earth’s atmosphere. However, when vitamin C and vitamin E are given to children with asthma, they are able to breathe better and feel much better, too. It seems C and E, both antioxidants, keep asthmatic bronchial tubes from constricting which results in wheezing less and breathing better.

 

Q. Which minerals do children need?

A. It is absolutely crucial that children get calcium, chromium, iron, magnesium, manganese, selenium, zinc, and phosphorus every day. Sadly, however, the majority of our children are not getting the recommended amounts of many of these vital minerals. Children in America today drink more carbonated soft drinks than milk and are in the midst of a calcium crisis. Green leafy vegetables, another good calcium source, are also negligible in teen diets.

According to statistics from the National Institutes of Health, only 13.5 percent of girls and 36.3 percent of boys age 12 to 19 in the United States get the recommended daily amount (RDA) of calcium. Because almost 90 percent of adult bone mass is established by the end of this age range, children today are in danger of being part of an osteoporosis epidemic in the future as they enter late adulthood.

Lack of adequate calcium has immediate consequences for children, as well. The number of fractures among children and young adults has increased as a direct result of poor calcium intake. Pediatricians are also seeing children with rickets, a bone disease caused by low levels of vitamin D. Rickets became almost nonexistent after vitamin D was added to milk in the 1950s, but, due to lower milk consumption, is now appearing at greater rates around the country. And milk itself can be problematic for some children. Aside from alarming reports of hormones and herbicides in commercial dairy factory milk, even organic milk is not tolerated by all because of lactose intolerance and allergies.

Zinc is another mineral that’s vital for children. Because zinc is critical for normal growth and development, children need to take it every day. A study published in the Journal of the American Dietetic Association, however, found more than half of US children ages two to 10 years fail to get the recommended daily allowance (RDA) for zinc. What’s even more troubling is that zinc is vitally connected to children’s ability to process information, pay attention, as well as remember and retain new information

Zinc does a lot to keep children healthy. More than 200 enzymes in our bodies rely on zinc. However, it’s zinc’s ability to connect with our immune systems to help fight infections that is crucial for children. While researchers are not certain how zinc precisely boosts a child’s immunity, they think that zinc might fight pneumonia and other infections by either enhancing the body’s immune status, preventing the infection from establishing itself, or improving the immune system’s ability to rid itself of the infecting organism. It’s possible that zinc does all three.

 

Q. No matter what I do, my children seem to come down with bad colds each year. Besides giving them a multivitamin, are there other nutritional supplements that can keep my children healthy?

A. Absolutely! In fact, there are 100% natural flavored children’s immune formula nutritional supplements that contain their good buddy zinc, vitamins B6, C, and A (as beta carotene), plus elderberry extract. Elderberry extract has been used as a traditional medicine for hundreds of years to treat colds and flu. And as it so often happens, scientific research has validated this use. In fact, scientists have discovered that elderberry keeps viruses from invading other cells and replicating. It also spurs important immune cells into action to fight invading germs.

While we previously discussed vitamin C’s ability to help children with asthma breathe easier, it also provides powerful immune protection. It speeds up the healing of wounds, such as those knee and elbow scrapes so common in childhood. However, vitamin C is a water-soluble vitamin and can’t be stored in the body. It must be replenished every day. When children are under increased stress (like when they get sick with a cold or flu), their vitamin C levels are more rapidly depleted.

Vitamin B6 is also water-soluble and can only work in children’s bodies for eight hours. Then more B6 must be obtained. Vitamin B6 strengthens the immune system by helping white blood cells make antibodies. Vitamin A helps make lysozymes, important anti-infectious agents found in tears, saliva, and sweat. It also stimulates the thymus gland, an important immune organ, especially in children, to work better.

 

Q. Should children take an immune formula every day or only when they are sick?

A. It can be taken several ways. Some parents may want to give the formula when school first starts or other times that their children are exposed to lots of germs. For a child who suffers from asthma or seasonal allergies or just seems to get sick frequently, parents could provide the immune formula every day, increasing the dose when needed. And still others might feel it’s best to give their children the immune formula only whey they do catch a cold or have the flu.

No matter how it is given, the 100% all natural flavored, immune boosting nutritional supplement can provide powerful protection against all those disease-causing germs your children are exposed to every day.

 

Conclusion

The nutritional choices we make for our children today will have a profound effect on their health tomorrow. Recent research has revealed that diabetes, heart disease, obesity, osteoporosis, and cancer in adults often result form nutritional deficiencies that occurred in childhood.

Thankfully, the reverse is just as true. This means that children who are well nourished with an optimal intake of minerals, vitamins, and helpful herbs can grow into healthy and happy adults. Providing high quality multivitamins and immune boosting nutritional supplements for our children can be an important part of that process.

 

Papaya- May Be A Fountain of Youth

 

Seventy years ago, when the Social Security Administration was developed during the Great Depression, age 62 was recognized as average life expectancy. These days, getting older is a whole different ball game. Not only are people living well into their 80s and 90s, they’re living better, too. People well into retirement are mountain biking, kayaking, jogging and hiking, as well as gardening, golfing and attending concerts – sometimes for their first time. Everybody, it seems, is on the go, from ages of 22 to 92.

 

Of course, you don’t have to wait until retirement to start planning for a longer more vibrant life. The best way to ensure happier and longer years ahead is to start young.

Nobody wants to spend retirement in the doctor’s waiting room or have their golden years intruded upon with illnesses or infirmities. And, most importantly, we don’t want to feel 80 years old even though our driver’s license says we are.

These desires and demands are not just wishful thinking. Huge advances in the understanding of how men and women age are being made almost daily. These findings are helping to improve our chances of living long, healthy lives. And, some of the most impressive findings have shown that using nutritional supplements can help – in particular, a specially formulated papaya preparation is able to fight two of the primary reasons we get old – oxidative stress and immune system decline.

This issue of Ask the Doctor is going to share the anti-aging secrets hidden in the papaya and how this tropical fruit may hold the key to a long, vibrant life.

 

Q. Why papaya? What does papaya have that other fruits and vegetables don’t?

A. Not many American moms put a papaya in their kids’ lunch boxes and papaya pie has yet to gain a following. But this tangy tasting fruit is now appearing fairly frequently in the produce departments of most grocery stores and its popularity seems to steadily increase each year.

The papaya’s bright orange flesh is fairly fibrous and very slippery – slicing a peeled papaya is a little like slicing a bar of wet soap. The core is filled with little black seeds that look a lot like caviar. And while eating a papaya will give you a day’s worth of vitamins A and C as well as potassium taking Fermented Papaya Preparation (or FPP) might just give you an additional 30 years of healthy vibrant life.

 

Q. What exactly is Fermented Papaya Preparation (FPP)?

A. It’s a specialized nutritional supplement. Backed by more than 30 studies to date, FPP has been used in Japan for decades. It’s also an extremely popular supplement in France and other parts of Europe. FPP begins with fresh, ripe papayas that are slowly fermented by a natural process that takes several months to complete. The fermented papaya is then dried and ground into a fine powder. This phytonutrient-rich powder can then be sprinkled in the mouth, dissolved, and swallowed.

 

Q. How was FPP developed?

A. Japanese scientists noticed that individuals with higher amounts of papaya in their diets experienced certain health benefits.

Researchers who study aging decided to look at the papaya’s chemistry to see if it might have properties that could contribute to longevity. Several plant chemicals in the papaya showed promise. And when they combined papaya with specific yeasts and traditional Japanese fermentation techniques, FPP was born. This unique substance was then subjected to scientific studies to see its health impact; they determined that FPP is a superior antioxidant, a powerful immune-booster, and one of Japan’s secrets to a long healthy life.

 

Q. How does FPP help people live longer and healthier?

A. While getting older is an indisputable fact of life, aging, per se, is not. We can’t do much about our annual birthdays and we really shouldn’t even if we could. Every age is a cause for celebration and every life experience, both the difficult and the sublime, should be treasured.

However, we don’t have to accept the consequences of aging that can make a mockery of the “Golden Years” - heart disease, Alzheimer’s disease, Parkinson’s disease, osteoporosis, arthritis, and cancer. Our parents and grandparents and the generations that preceded them might have had little say in how they aged. But we can. We can slow down the harmful effects of aging and FPP can help by reducing oxidative stress and immune system decline.

Additionally, fighting oxidative stress helps people retain their youthful appearance longer. Oxidative damage is the number one factor in facial aging.

 

Q. What exactly does oxidative stress mean and what does it have to do with aging?

A. One theory of aging is that harmful molecules called free radicals wreak havoc in our cells. Many of our body’s normal metabolic processes produce free radicals. For example, free radicals are a normal by-product in the production of ATP (the energy molecule) from glucose. Certain types of white blood cells destroy invading microbes by the production of free radicals. Free radicals are also formed by the many normal enzymatic actions that take place every minute every day.

However, outside sources can also cause free radical formation, as well. If we are exposed to pollutants in the environment, chemicals, additives and preservatives in the food we eat, or even direct sunlight, excess production of free radicals can occur, causing profound damage. This free radical frenzy is called oxidative stress, and is linked to almost every disease of aging including arthritis, heart disease, cataracts, Alzheimer’s disease, Parkinson’s disease, and cancer. In fact, the reason why these are called diseases of aging is because the longer we are alive, the longer we are subjected to these free radical assaults.

 

Q. How does FPP affect the decline of our immune systems as we age?

A. Our immune systems consist of specialized tissues, organs, and cells, including several different kinds of white blood cells. Each type of white blood cell works in specific ways to keep us healthy and free of disease. They not only stand guard – on the alert for invaders – they can fight and eradicate microbes, too.

However, as we age, our white blood cells become less efficient in keeping viruses and bacteria from infecting us. They often mistake invaders for good guys, like nutrients. As they age, white blood cells may recognize foreign invaders, but be too tired to fight and let them in. This age-associated immune decline also results in single cancer cells being able to “take hold” and grow into tumors. By the time the white blood cells realize their mistake, the cancer is a widespread disease.

That’s why older members of society have more urinary tract infections, more pneumonia, more cases of bacterial meningitis, tuberculosis, herpes zoster, and much more cancer than younger adults do. Moreover, mortality rates for these diseases are often 2-3 times higher among adults than younger people with the same disease.

FPP steps in and takes charge. One kind of white blood cells, the macrophage “eats” and digests bacteria, viral particles, and free radical fragments. Research has shown that FPP helps macrophages work faster and ingest more disease-causing microbes. Scientists have also discovered that FPP increases the production of a chemical protein called interleukin that’s secreted by macrophages. Interleukin plays an important part in wound healing and keeping minor infections from becoming major infections.

Another important immune system cell is the natural killer (NK) cell, a white blood cell that is continually on the prowl for cancer cells. As the immune system ages, NK cells have trouble “seeing” cancer cells. Researchers have discovered that FPP boosts the activity of NK cells. Increased NK cell activity can result in the increased killing of cancer cells as well as cells infected by viruses.

 

Q. How does FPP help protect us from free radical damage?

A. FPP contains unique and powerful antioxidants. Antioxidants are molecules that neutralize free radical damage. Antioxidants do this by donating an extra electron to the free radical without becoming frenzied or worked up into a free radical themselves. Although the antioxidant has donated an electron, it has a more stable “personality” and is less reactive. This action stops the domino effect and ongoing free-radical damage.

If you consider your body a temple, think of free radicals as stealing bricks from your temple’s foundation. FPP acts not only as policeman, but as a builder as well. It doesn’t just stop the theft of bricks; it helps create new ones, keeping the foundation strong and young.

FPP does this by affecting super oxide dimutase (SOD) and glutathione peroxidase (GPX), the very genetic pathways that eliminate free radicals from the system. FPP is more than an antioxidant – it doesn’t turn into a pro-oxidant if you happen to take a large dose the way standard antioxidants can. Consider it an “antioxidant plus.”

Since aging is largely determined by how well our bodies can fight oxidative damage, using FPP can slow down the clock as it bolsters natural abilities with its own potent neutralizing activities.

 

Q. What else does science say about FPP?

A. As the subject of over 30 clinical studies, FPP has been shown to inhibit dangerous hydroxyl free radicals. In addition, it is also being considered for its immuno-protective effects.

Researchers and medical professionals have been studying FPP for years, tracking its effect on the immune system and aging. In fact, no less a personage then Dr. Luc Montagnier, co-discover of HIV 1 & 2 virus, has been conducting research on this natural immune booster.

Dr. Montagnier recommends using FPP as part of a tri-therapy (including antibiotics) that reduces the proliferation of the virus and stimulates the immune system. Since FPP has antioxidant and immuno-stimulative properties, it seems like an obvious choice for a combined approach to combating AIDS. Because of the higher free radical production in stage II of HIV infection, Montagnier believes that reducing this oxidative stress at the earliest stage of HIV infection may be a key factor.

In HIV-infected patients, the glutathione system is depressed even at the early stages. As part of a combination treatment, FPP increased the numbers of CF4 lymphocytes helped with weight gain and increased hemoglobin levels.

One scientific study showed the ability of FPP to inhibit dangerous hydroxyl and hydroxyl-like free radicals, while enhancing the production of protective super oxide. Other research by Dr. Lester Packer, a professor of Molecular Pharmacology and Toxicology at the University Of Southern California School Of Pharmacy, shows FPP to have natural iron chelating effects and prevents lipid peroxidation.

And, in one randomized, double blind, placebo-controlled clinical trial, patients with cirrhosis of the liver were given FPP or a placebo. The results showed that 81.2% of the patients survived in the FPP group compared to 38.5% of participants in the placebo group.

These studies and many others like it, show that FPP can neutralize the effects of oxidative stress on disease states as well as slowing the normal aging process.

 

Q. So if we can prevent oxidative damage to our cells AND prevent decline in our immune systems, how much longer can we expect to live?

A. Most theories of aging and almost all researchers who study aging claim there IS a limit to how long the human body can remain viable. However, the oldest age achieved so far was 128 by a woman named Ma Pampo who lived in the Dominican Republic. Other notable oldsters include Jeanne Louise Calment of France, who lived to be 121; Elena Slough, of Trenton New Jersey who lived for 114 years and 112-year old Mary Dorothy Christian who lived and died in San Pablo, California.

Right now, Japanese women have the longest life span of any country in the world, with an average life expectancy of 85.93 years. Japanese men live an average 78.87 years. Japan also has more centenarians – people living to age 100 and beyond – than any other country as well. There is no reason why the rest of the world, the USA included, can’t achieve these average life expectancies and, hopefully, even surpass them.

 

Q. Is FPP safe?

A. Yes, it is. Many health-conscious people in Japan and Europe have used FPP for many years as an anti-aging product without any side effects.

 

Q. What is the recommended dosage level of FPP?

A. Dosages of FPP vary depending on individual needs and usage. For basic anti-aging support, 3 grams per day is fine. For additional support, up to 9 grams per day is recommended. To add a boost to your immune system when you need it, start out with 6-9 grams a day for the first 2-3 days (at the beginning of a cold, for example) and then move back down to 3 grams per day.

For individuals looking for optimum immune support, Dr. Montagnier advises morning and evening doses, preferably on an empty stomach.

 

Conclusion

As America’s Baby Boomers turn 65, they are living proof that the milestone is no longer the herald of old age. It’s just one more stepping stone from where we’ve been – to where we are – and on to where we want to go. Using Fermented Papaya Preparation, we can feel younger, look younger and live younger – to a very old age.

Improving Sexual Performance Naturally

Sex. It’s everywhere. It’s on TV (a lot!). It’s in the books we read and the movies we watch. Even the radio seems a veritable hot bed of sex. (what would hard rock, soft jazz, or Motown classics be without songs about sex?) Magazines are full of sex and it’s not just the “naughty” ones with glossy centerfolds. From Sports Illustrated to Good Housekeeping, sex makes for titillating headlines and cover stories. In fact, 21^st Century America seems to be awash in sex, except where it counts – in the bedrooms and love lives of married Americans.

No one really knows for sure how many of the 113 million married Americans are living as couples with DINS (dual income, no sex). Estimates range from 15 to 50 percent. Even couples who have sex fairly often feel like they’re not having enough sex or that it’s not as enjoyable as it was in the past, or both. And while women are stereotyped as the sex refusers and avoiders, surveys show that both women and men decline spousal advances fairly equally.

What’s really interesting about this lack of sexual activity in America, is that the very same thing is happening to husbands and wives residing in Paris and London, as well as Lisbon and Madrid. Research has shown that married couples who reside within Western civilized countries are much more likely to have unhappy sex lives than their counterparts living elsewhere in the world. That’s because the married couples residing in the rainforests of Brazil, the streets of Beijing, and the mountains of Tibet have access to powerful plant medicines that keep their sexual relationships healthy and happy. In fact, in China and India alone, over one billion men and women routinely incorporate plant medicines for healthy and satisfying sex.

As a medicine hunter, I have discovered effective plants and herbs al over the planet that really do improve orgasms in women and erections in men. Now it’s your turn. I’m going to teach you how to enhance your sexuality and introduce you to an entire arsenal of libido lifting plants to help make sex fun, vibrant, and satisfying for both you and your partner.

 

Q. These plants sound too good to be true. Do they really work?

A. Yes, they do. Part of their success is their ability to work with your body’s innate mechanisms for healthy sex. Good sex is much more than just stimulated body parts. But it’s a good place to start!

A man needs an erect penis that remains firm past foreplay and on into intercourse. He also needs to sustain that erection and experience forceful and pleasurable ejaculation when he and his partner are both ready for his orgasm. A woman needs to feel desire and feel desired for her nipples to be aroused, her clitoris stimulated, and her vagina lubricated – the basics leading to her orgasm.

Plants that enhance sex can help men and women obtain these bare necessities of sex. And unlike other supplements, you’ll know if the medicinal plant you’ve purchased is actually doing what it promised to do. You can’t really tell if the calcium supplement you take each day is making your bones stronger. But you will be able to tell pretty soon if Catuaba, for example, is increasing your sexual desire.

Q. Night after night, my husband falls asleep on the sofa. And the honest to goodness truth is that I’m too tired for sex, too. I love my husband and once upon a time I loved sex. But my job, the kids, those never-ending errands, and trying to keep up with the laundry are too exhausting. Is there a plant that can rev us up?

A. Many women are in the same sexless boat you’re sailing around in and they don’t like it any more than you do. In fact, women all over the world put their family’s needs before their own, leading to some very tired moms and wives.

Life’s demands can also impair sexual performance in men. Work stressors, family demands, and home maintenance result in fatigue and lack of energy. Men find that they have no energy left to devote to to sex at the end of the day.

But, over 80 percent of married couples in the world have at their disposal a health care system that integrates sex into their personal health and well being. For centuries, millennia actually, practitioners of traditional medicine have prescribed Maca and Rhodiola to reduce “sexual fatigue” in women and men who are just too tired to make love.

 

Sex Enhancing Plants for Men and Women	How They Work
Maca (Lepidum meyenii)	For the past several years in Peru, where the Maca plant grows, physicians have prescribed extracts from this plant to men with low libido and diminished erectile function, which excellent results. Recently researchers studying Maca have discovered two compounds they think are responsible for improved sexual stamina, namely the macamides and macaenes. It is these same compounds that help men and women obtain more frequent and more powerful orgasms.
Rhodiola Rosea	This hardy plant grows high in the mountains of Europe and Asia, enduring cold and snow and lack of sunlight for much of the year. Hoping to gain some of Rhodiola’s energy and stamina for themselves, early Siberians used extracts of the plants to boost strength and stamina. Not only did they have more energy, they discovered they had more sexual stamina, too.   Rhodiola is an adaptogen, a plant that helps us adapt to changes in life and the stresses of everyday life. When we’re stressed, our bodies shift into high gear causing a cascade of hormones to prevent and reduce harm. In cases of trauma (like car accident or surgery (or simply nature at work (such as childbirth), these hormones are necessary. However, when we experience stress that’s caused by work (your boss), or family (your teen-aged children), or personal struggles (your weight), this hormonal cascade can do more harm than good –causing fatigue, added weight gain, poor metabolism, and impaired sexual function.   Rhodiola helps make sure the hormonal cascade occurs when it’s needed, to protect our health, not harm it. The result is better energy, better vitality, and better sex!

Q. Since I had a baby four months ago, I have no desire for sex. This is making my husband pretty frustrated and me too, actually. I’d love to want sex again.

A. A married woman with a baby and a toddler or two can feel that her body isn’t really hers. So much for feeling sexy! While this fact can be a source of great pride and joy, it can also drain desire.

As women enter perimenopause – those years when they are still menstruating despite fluctuating estrogen levels – they often have no desire for sex. Since estrogen is the engine that drives women’s reproductive function, when it starts to go, sex goes too. Women who have reached menopause may find their minds wandering during sex. Pondering the car’s need for an oil change or if the milk in the refrigerator has reached its expiration date makes for pretty blah sex. It also makes it nearly impossible to achieve orgasm.

Once more, traditional medicine has some answers:

Sex Plants for Women	How They Work
Ashwagandha (Withania somnifera)	Just like Rhodiola, Ashwagandha is an adaptogen, possessing powerful sex-enhancing powers. And just like Rhodiola, Ashwagandha has been helping women boost their desire for sex. Long considered India’s most potent sex-enhancing plant, the country’s women have used Ashwagandha for years to rev up their sex drives.
Catuaba (Erythroxylum Catuaba)	Catuaba is a tree that grows in the dense, lush Brazilian Amazon, the largest tropical rainforest on Earth. For hundreds and hundreds of years, tribal peoples have used Catuaba bark to stimulate sexual desire. According to folk legend, the Tupi Indians discovered Catuaba bark’s sex-enhancing effects and passed the knowledge on to other rainforest tribes. Today, Catuaba is used worldwide by women desiring passionate sex.
Eleuthero (Eleutherococcus senticosus) extract	Sometimes called Siberian ginseng, Eleuthero is actually not a ginseng at all, only a distant cousin. This leafy shrub is native to Eastern Russia and the mountains of China and has been used by tribal peoples for over 2,000 years to eliminate sexual fatigue. Eleuthero is another adaptogen, invigorating sexual function and restoring balance to all body functions.

Q. My husband has a desire for sex, but sometimes it’s not enough. Even if we’re both in the mood, he can’t maintain his erection very long. It’s very frustrating for us both.

A. For men it’s often their equipment that lets them down. As men age, they find they can’t get an erection hard enough or keep an erection long enough to satisfy their partners and themselves.

While women can fake an orgasm if they’re tired, men have to perform every single time they have sex. Luckily, Mother Nature can help:

Sex Plants for Men	How They Work
Horny Goat Weed (Epimedium species)	This aptly named sex plant has been in use for over two thousand years, restoring sexual fire, treating impotence, and increasing production of semen. The green leaves of Horny Goat Weed are filled with numerous natural compounds, responsible for these sexual effects. Research shows that horny goat weed has activities very similar to the androgens, sex hormones that stimulate desire in men.
Yohimbe (Pausinystalia yohimbe)	Yohimbe is nature’s Viagra – it helps men attain firm erections. Not surprisingly, Yohimbe has been used for a long time as a fold medicine aphrodisiac. The bark contains Yohimbine, a compound known to stimulate engorged vessels within the penis and nerves of the lower spine. It’s no wonder Yohimbe has the well-deserved reputation as a superior sexual stimulant.
Panax ginseng	One of the most highly regarded plants in traditional Chinese medicine, Ginseng stimulates the central nervous system, invigorates the brain, increases resistance to stress and fatigue, and sharpens the mind. Ginseng is also used by millions of men to enhance libido and sexual vitality. In an erectile dysfunction study, men who took Ginseng had a 42% improvement in erectile function compared to placebo. Researchers theorize that ginseng increases nitric oxide in the penis, dilating the vessels of the corpus cavernosum - the very same mechanism that makes Viagra work.

Q. There are hundreds of supplements that claim to make men hard and women weak with desire. I’ve tried some of these, and they don’t do anything. When should I believe that the herbs and plan medicines you have discovered are nay better?

A. There are a lot of “snake oil” companies out there pitching products that promise to improve our sex lives but do absolutely nothing. One reason for this glut of useless supplements is simple demand. Men and women trying to make their sex lives better, are willing to give most products the benefit of the doubt and buy one or two. Sex sells – and even products that are purchased one time only will make big profits.

To get the most for your money, make sure the sexual supplement you are considering is from a well-respected manufacturer. Ask store staff, surf the Internet, and do some searching for the best nutraceutical companies. Make sure the herbs are standardized and that the extracts are concentrated fro optimal benefit.

Q. Are these sex-enhancing plants safe?

A. Despite years of use by practitioners of traditional medicine, significant adverse effects have not been reported for most sex-enhancing plants. However, men who have already been diagnosed with certain health conditions such as high blood pressure, thyroid disease, prostate problems, or other illnesses should use caution when selecting any health supplement. The same advice applies to women, especially women who are pregnant or nursing. And always remember to keep your doctor informed about the supplements you are using, especially if you are also taking prescription drugs. But the sex-enhancing plants have been traveling on planet Earth for a long, long time. And hopefully they’ll be here for lot longer, continuing to work effectively and go about their business of safely improving orgasms and erections and making sex great for men and women all over the world.

Q. OK, exactly how did early native healers figure out which plants improve sex? Was it just simple trial and error?

A. It does seem pretty remarkable that tribal peoples have discovered the right plants to treat diseases and improve health without modern day scientific advances.

From my many years as a “medicine hunter” in rainforests and grasslands and marshes and mountains, I’ve learned that healing plants exist for virtually every health need. It’s up to the medicine man or women to put the plant into practice. These healers have been able to do this successfully for thousands of people, by intensively studying and working with the plants. By putting themselves into the plant’s world, becoming part of the world around them, native healers have intuitively discovered which plant helps which disease. It wasn’t mere luck that brought all those plants and all those healers together. It was the natural and spiritual connection existing between the two.

Q. Are there other “natural” remedies we can use to improve our sex lives?

A. The easiest way to naturally enhance your sex life is to practice, practice, practice! Because if you don’t use it, you might lose it. Studies have shown that couples in the Amazon rainforest as well as couples in the concrete jungle of New York City have better sex lives if thy make sex a priority. All the sex-enhancing plants in the world are useless if the men and women taking them don’t put them to the test.

Men who smoke need to quit. Research has shown that cigarettes send men’s sex lives up in smoke. Men who smoke more than 20 cigarettes daily have a 60 percent higher risk of erectile dysfunction compared to men who never smoked. That’s because smoking decreases blood flow making it difficult for men to obtain an erection.

And finally, since sex is a visual and tactile endeavor, there are quite natural and creative ways to give it a boost. Visually stimulating images can arouse even the tiredest of the tired. Premiere Magazine recently compiled a list of the most erotic movie sex scenes ever. You don’t have to feel embarrassed when renting these movies (as you might with pornography) at the video store and they are guaranteed to light up your life:

1.      Diane Lane and Oliver Martinez making love in UNFAITHFUL (2002)

2.      Hilary Swank pleasuring Chloe Sevigny in BOYS DON’T CRY (1999)

3.      Brad Pitt and Claire Forlani making love in MEET JOE BLACK (1998)

4.      Leonardo DiCaprio drawing Kate Winslet in the nude in TITANIC (1997)

5.      Sharon Stone uncrossing her legs while she is being interrogated in a room full of en in BASIC INSTINCT (1992)

6.      Patrick Swazye and Demi Moore in the pottery secene early on in GHOST (1990)

7.      Michael Douglas and Glenn Close having sex in an elevator in FATAL A TTRACTION (1987)

8.      Mickey Rourke caressing Kim Basinger’s body with an ice cube in 9 1.2 WEEKS (1986)

9.      William Hurt and Kathleen Turner having sex in BODY HET (1981)

10.  Julie Christine and Donald Sutherland making love in DON’T LOOK NOW (1973)

11.  Rita Hayworth flipping back her hair and singing “Put The Blame on Mame” in FILDA (1946)

One Important Last Point

Sex always has consequences. And improving your sex life does not eliminate the requirement to practice it responsibly. Sexually transmitted diseases, hepatitis, and HIV/AIDS must be prevented, pregnancy must be considered and consent between partners must exist.

Conclusion

Sexual activity keeps us connected – both tangibly and spiritually to our heart’s desire. It helps us feel secure and well loved and adds to our self esteem. In other words, good sex is important to good life.

But all of us need a little help now and then. Sex-enhancing plants that have been used for thousands of years by millions of people provide that help. You can have actual sexual healing with effective sexual supplements and maybe find out what you’ve been missing.

After all, 80 percent of the world’s married couples can’t be wrong!

CoQ10 for Heart Health

 

More than 40% of all deaths in the U.S. are from cardiovascular disease (CVD). You have a greater chance of dying from heart disease than from cancer, AIDS, diabetes, and accidents combined. More than 2,600 Americans die each day of CVD – an average of 1 death every 33 seconds. One in 5 men and women have some form of CVD. If all forms of major CVD were eliminated, life expectancy would rise by almost 7 years.

One of the most – if not the most – important things people can do to improve their overall health and life expectancy is to improve their heart health. Diet, exercise, and the wise use of dietary supplements can improve heart health dramatically. One dietary supplement that’s extremely beneficial to heart health is coenzyme Q10 (CoQ10).

 

Q. What is CoQ10?

A. CoQ10 is a natural, fat-soluble nutrient present in virtually all cells. CoQ10 also is known as ubiquinone. That’s because CoQ10 is ubiquitous and exists everywhere there is life. CoQ10 is vital to adenosine triphosphate (ATP) production. ATP is the energy-rich compound used for all energy-requiring processes in the body. Although COQ10 is produced by the body and exists in some dietary sources, these levels may be insufficient to meet the body’s requirements. CoQ10 levels diminish with age and as a result of dietary inadequacies and various disease states. Also, some drugs, especially a group of cholesterol-lowering prescription drugs known as “statin,” (Pravachol, Zocor, Lipitor, etc.) significantly reduce CoQ10 levels in the body.

 

Q. For what health conditions is CoQ10 used?

A. CoQ10 is beneficial in treating and preventing CVD and conditions such as high blood pressure, atherosclerosis (hardening of the arteries), angina, and congestive heart failure (CHF). It’s been shown that heart attacks tend to occur when CoQ10 levels are low in the body. In addition, CoQ10 is beneficial for diabetes, immune dysfunction, cancer, periodontal disease, prostate cancer, and neurological disease.

 

Q. Why is CoQ10 especially important to heart health?

A. The heart is one of the most metabolically active tissues in the body. In the average person, the heart propels 2,000 gallons of blood through 65,000 miles of blood vessls by beating 100,000 times each day. Thus, it requires large amounts of uninterrupted energy. Heart cells have a greater number of mitochondria, and subsequently, more CoQ10 than any other type of cell. Each heart cell can have thousands of mitochondria to meet these energy demands.

 

Mitochondria are highly specialized structures within each cell and are often referred to as cell powerhouses. These tiny energy-produces produce 95% of the energy the body requires. The number of mitochondria in a cell depends on its function and energy needs. A cell’s ATP production is dependent on adequate amounts of CoQ10.

 

Heart disease patients are commonly CoQ10 deficient. Correcting such deficiencies often can produce amazing results. The presence of supplemental CoQ10 is a key to the heart’s optimum performance.

In people who have had a heart attack (myocardial infarction), CoQ10 assists in repairing the heart muscle and restoring heart function. This is due to increased ATP production.

 

Q. What studies support this fact?

A. A 1998 study found CoQ10 can provide rapid protective effects in patients with a heart attack if administered within three days of the onset of symptoms. The study focused on patients admitted to the hospital with an acute myocardial infarction (AMI) diagnosis. Seventy-three patients received CoQ10 (120 mg/d). The study’s control group consisted of 71 similarly matched patients with acute AMI. After treatment, angina pectoris (severe chest pain signifying interrupted blood flow to the heart), total arrhythmias (dangerously irregular heartbeats), and poor function in the left ventricle (the essential chamber of the heart) were significantly reduced in the CoQ10 group compared to the placebo group. Total deaths due to sudden cardiac failure and nonfatal heart attacks also were significantly reduced in the CoQ10 group compared with the placebo group.

 

In another study, CoQ10 was studied in 109 patients with high blood pressure (hypertension). The patients were given varying doses of supplemental CoQ10 with the goal of attaining a certain blood level (greater than 2.0 mcg/l). Most patients were on medications to treat hypertension. Half the patients were able to stop taking one to three antihypertensive drugs at an average of 4.4 months after starting CoQ10. Only 3% of patients required the addition of one antihypertensive drug. The 9.4% of patients who have echo cardiograms, performed both before and during treatment, experienced a highly significant improvement in heart wall thickness and function. This improvement was directly attributed to CoQ10 supplementation.

 

Congestive heart failure (CHF) is a debilitating disease that affects 5 million people in the U.s. It causes edema, difficult breathing, and impaired circulation. In another study, CoQ10 restored healthy heart function in CHF patients. Patients received 100 mg of CoQ10 or a placebo twice daily for 12 weeks. Before and after the treatment period, the investigators introduced a catheter into the right ventricle of patients’ hearts to determine the degree of CHF damage to the heart muscle. The patients’ heart muscles at rest and work improved significantly. The researchers concluded CHF patients would greatly benefit from adjunctive CoQ10 treatment.

 

Q. I’ve heard that CoQ10 can also help people who have neurological diseases. Is this true?

A. Yes, it is. CoQ10 has been studied for its ability to improve the health of individuals with amotrophic lateral sclerosis (ALS), Parkinson’s disease, and Huntington’s disease. A recently completed study sponsored by the National Institutes of Health showed that CoQ10 caused a slowing of the progression of Huntington’s disease, a devastating and degenerative disease that is always fatal. In fact, no other medication, drug, or nutritional supplemental has ever been shown to cause a decline in the progression of this terrible disease.

 

The study compared CoQ10 against remacemide (an investigational HD drug made by AstraZeneca Pharmaceuticals), in 347 HD patients who were in the early stages of the disease. Remacemide blocks glutamate, the neurotransmitter scientists think may cause the death of brain cells that occurs in Huntington’s disease. While remacemide had no effect on the progression of HD, CoQ10 showed a trend toward slowing the disease by an average of 15%. This meant the HD group taking CoQ10 was able to handle every day activities of life a little longer than the patients taking remacemide or a placebo. They also were able to focus their attention better, were less depressed, and less irritable. The 15% slowing of decline means that CoQ10 can result in about one more year of independence for HD patients. Needless to say, the gift of an additional year of health in the lives of HD patients is incredibly significant.

 

Because of these impressive results with HD, researchers are hopeful that the studies of CoQ10 in those with ALS and Parkinson’s disease will similarly have a positive effect on the symptoms and/or progression of these neurological disorders, too.

 

Q. Why is it crucial for a CoQ10 supplement to cross the blood-brain barrier?

A. The brains’ blood vessels are composed of cells with extremely tight junctions. These junctions form the blood-brain barrier, which restricts what can pass from the bloodstream into the brain. While this barrier protects the brain, it can be a significant obstacle to central nervous system therapy. To leave the bloodstream and reach the brain cells, a substance must pass through the tightly connected cells of the capillary walls. Only substances with unique solubilities or those with a transport system can cross the blood-brain barrier to a significant degree. As a result, crossing the blood-brain barrier presents a significant challenge to supporting neurological health.

 

While most CoQ10 supplements enter the bloodstream and increase blood serum levels, only special forms of CoQ10 have been shown to cross the blood-brain barrier. For CoQ10 to enter the mitochondria within the brain, CoQ10 must first cross the blood-brain barrier to produce significant neurosupportive clinical results.

 

Q. How can one supplement have applications for neurological diseases, heart health, and even the immune system?

A. Supplements often have more than one function, especially when it’s a substance like CoQ10, which is present in all parts of the body. All nucleated cells (most cells other than red blood cells) have mitochondria and all cells require energy to function. CoQ10 is vital to ATP production. Thus, CoQ10 has applications not only in neurological (neurons or nervous system cells) and cardiac health (myocardium or heart tissue), but also for the immune system.

 

Q. Are all CoQ10 supplements created equal? Doesn’t CoQ10 just have to get into the bloodstream to be effective?

A. There are some important distinctions among CoQ10 products, as they vary greatly in quality and absorbability. It’s crucial to find a CoQ10 product that’s:

 

1. Scientifically shown to absorb through the digestive tract, cross cellular membranes, and increase mitochondrial levels of CoQ10. Chewable forms of CoQ10 provide rapid bioavailability and absorption. Serum level determination of CoQ10 in the bloodstream is not necessarily the most important measure of efficacy. For a CoQ10 supplement to be fully effective, it must cross the cellular barrier and raise intracellular CoQ10 levels. A key indicator of effective CoQ10 supplementation is its presence in cell mitochondria.

 

2. The natural form of CoQ10. The natural process uses living organisms. CoQ10 also can be synthesized by a chemical process, which produces a distinctly different product that contains chemical compounds not found in the natural form.

 

3. Formulated with ingredients that provide the transport system CoQ10 needs to cross cellular membranes and the blood-brain barrier. Not all forms of CoQ10 have been scientifically proven to cross cell membranes and the blood-brain barrier. Some prestigious groups that have investigated this issue include researchers at Massachusetts General Hospital and Harvard Medical School.

 

4. Studied by respected organizations, with research published in peer-reviewed journals by reputable scientists.

 

Q. How much CoQ10 should I take?

A. Take 100 to 200 mg of CoQ10 daily, depending on your family history of heart disease and personal heart disease experience.

 

CoQ10’s safety has been evaluated. Dosages in studies have ranged from 100 mg to 1,200 mg per day. To date, no toxicities have been reported. Occasional mild stomach upset may occur. Taking CoQ10 with meals usually alleviates this rare effect.

 

Q. What are some other heart-friendly supplements?

A. CoQ10 is an excellent supplement for overall cardiovascular health, as in L-carnitine. L-carnitine is the naturally occurring form of carnitine that’s found in food and synthesized in the body. Much of the body’s L-carnitine is found in the heart and skeletal muscle, tissues that rely on fatty acid oxidation for most of their energy. Nearly 70% of the energy needed for heart function is derived from fatty acid breakdown. Proper L-carnitine supplementation transports fatty acids into cell mitochondria, where it’s burned for energy. L-carnitine is an excellent addition to CoQ10, especially for people with heart disease, and has been shown to improve many symptoms associated with CVD. In one study, people who had experienced one heart attack received either L-carnitine or placebo. The L-carnitine group had a statistically significant reduction in second heart attacks, and improved overall survival.

 

Q. What supplements support healthy blood pressure and cholesterol?

A. In addition to maintaining overall cardiovascular health, it’s also important to address your essential fats/lipids levels and healthy circulation/blood pressure. Fish oil supplements can significantly reduce blood pressure, cholesterol, and homocysteine levels. Choose a supplement that’s a rich source of EPA and DHA, omega-3 fatty acids naturally obtainable in fish oil. Find a product that’s been clinically studied and purified to ensure it contains the beneficial active constituents of the whole oil, while removing any dioxins, DDT, PCBs, or heavy metals, toxins present in some commercial fish oil preparations. An enteric-coated garlic product that provides a minimum of 5,000 mcg of beneficial allicin supports healthy blood pressure and circulation. And magnesium, niacin, vitamin E, folic acid, hawthorn extract, and L-cysteine provide overall nutritional support to the heart and vascular system.

 

Conclusion

CoQ10 is not the only answer to the complex issues of heart disease, neurological disease, or immune dysfunction; however, research indicates that it’s a bigger piece of the puzzle than physicians and scientists ever imagined. The more we study this naturally occurring compound, the more benefits we find.

The key to this supplement is the manufacturing quality. For safety and overall effectiveness, use a CoQ10 product that’s supported by product-specific research from reputable institutions. Choose tested products from a well-respected company to increase your potential to achieve and maintain heart and blood vessel health.

Supplementation with clinically studied products can have a major impact on your heart’s health and strength. However, no supplement replaces the need to eat a healthful diet low in refined foods (especially sugar), and saturated fats, and to exercise your most important muscle – your heart – on a regular basis.

 

 

Regulating Blood Pressure Naturally

 

High blood pressure (also known as hypertension) affects about 65 million Americans, or about 1 in 3 adults. There are many potential causes of hypertension, but not necessarily any symptoms. In fact, 30% of the people who have high blood pressure don’t even realize it.

In other words, just because you don’t have symptoms doesn’t mean you don’t have high blood pressure. That’s why it’s called “The Silent Killer.” And, make no mistake about it: high blood pressure is dangerous. It is the number one modifiable cause of stroke. Just lowering blood pressure reduces the chance of stroke by 35 to 40 percent. Other conditions, including heart attack and heart failure can be reduced from 25 to 50 percent, respectively.

In this issue of Ask the Doctor, we’re going to talk about high blood pressure and an exciting natural treatment for lowering blood pressure safely and effectively.

Of course, changing blood pressure numbers depends, in a large part, on the choices we make every day – how much we exercise, the foods we eat, and our lifestyle overall. But, for those times we need extra help, there is a new, scientifically-studied supplement to help us along our path to better health and lower blood pressure.

 

Blood pressure guidelines from the National Heart, Lung, and Blood Institute.

Category	Systolic (mm/Hg)	Diastolic (mm/Hg)	Result
Normal	Less than 120	And Less than 80	Excellent!
Prehypertension	120-139	Or 80-89	Make changes in eating and drinking habits, get more exercise and lose any extra pounds.
Hypertension	140 or higher	Or 90 or higher	You have high blood pressure. Talk to your healthcare professional on how to control it.

 

Q. What exactly is blood pressure?

A. Blood pressure is divided into two parts, systolic and diastolic. Systolic is the pressure of the heart beating. Diastolic is the pressure of the heart and vessels filling. When blood pressure numbers are written out, like “120/80,” 120 is the systolic pressure and 80 is the diastolic pressure. The unit of measurement for blood pressure is millimeters of mercury, written as “mm/Hg.”

 

Q. What is considered high blood pressure?

A. A person’s blood pressure can naturally vary throughout the day – even between heartbeats.

However, if the numbers are consistently high (over 120 systolic and 80 diastolic), after multiple visits to your healthcare practitioner, you may have either pre-hypertension or high blood pressure.

Young arteries and arteries that are kept young through healthy diet and exercise are typically more elastic and unclogged. Blood flows through them easily and without much effort. However, as we age, our arteries become more prone to plaque buildup (due to diets high in saturated fat and sedentary lifestyles) and don’t “flex” as well under pressure. The result is faster blood flow, all the time. Over the long term, it damages heart tissue, arteries, kidney and other major organs.

To get a better idea of high blood pressure, compare your arteries to a garden hose. When unblocked, a garden hose allows water to flow through it quickly and easily – without any real rush or stress. However, if you block the end of the hose with your thumb, closing it off even a little, water rushes out much more quickly.

For many years, high diastolic pressure was considered even more of a threat than high systolic pressure. That thinking has changed somewhat but high diastolic numbers could still mean organ damage in your body – especially for individuals under 50.

 

Q. What courses high blood pressure?

A. The reasons for hypertension aren’t always clear. However, there are lifestyle factors that contribute to high blood pressure that you can change:

 

Body type: Weight isn’t always a reliable indicator of whether or not you’ll have high blood pressure – but the type of weight is. Lean body mass – muscle – doesn’t increase blood pressure levels the way that fat can. However, fat body mass, especially fat around your middle, can contribute to high blood pressure.

 

Sedentary lifestyle: Too often, many of us sit down all day at work, and then sit down all night at home. Over time, this inactivity usually leads to weight gain, making the heart work harder to pump blood through the body. In a way, it almost seems contradictory, but inactivity usually leads to higher heart rates.

 

Sodium intake: Sometimes it’s hard to believe how much salt there is in processed foods. However, salt intake in itself is not necessarily bad. For people with a history of congestive heart failure, ischemia, and high blood pressure, sodium is definitely out. For those individuals, it leads to more water retention, which increases blood pressure. (Salt’s effect on water retention is one reason that so many sports drinks have fairly high sodium content – the sodium in the drink prevents your body from sweating out too much water.) But, for healthy individuals, moderate salt intake, especially a mixed mineral salt like sea salt or Celtic salt (good salt should never be white) is fine.

 

Low potassium intake: Unlike sodium, potassium is a mineral which most Americans get too little of. Potassium helps regulate the amount of sodium in our cells, expelling excess amounts through the kidneys. Low levels of this mineral can allow too much sodium to build up in the body.

 

Heavy alcohol intake: Having three or more alcoholic drinks a day (two or more for women) nearly doubles an individual’s chance of developing high blood pressure. Over time, heavy drinking puts a lot of stress on the organs, including the heart, liver, pancreas and brain.

 

Unhealthy eating: Eating a lot of processed or fatty foods contributes to high blood pressure. Adapting a diet that is rich in fruits and vegetables, whole grain products, fish, nuts and magnesium and potassium (like the Dietary Approaches to Stop Hypertension, known as the “DASH” diet) can bring it back down.

 

Smoking: If you smoke, stop. Smoking damages the heart and arteries – period. Nicotine constricts blood vessels, increases heart rate, and raises blood pressure. This in turn, increases hormone production and adrenaline levels, further stressing the body.

 

As if that weren’t bad enough, the carbon monoxide in cigarette smoke replaces the oxygen in the blood, making the heart work even harder to make up the difference. Since the effect of a single cigarette can last for an hour, smoking throughout the day leads to continuously revved-up blood pressure.

 

Some of these factors might sound like a lot to overcome. The important thing to remember is that all of these behaviors are changeable. If you have high blood pressure, modifying any of these can significantly lower blood pressure as part of an overall plan.

 

Q. What are the blood pressure numbers I should see?

A. Experts consider healthy blood pressure numbers to be 115/75 mm/Hg. The reason? They found that the risk of cardiovascular disease doubles at each increment of 20/10 mmHg over 115/75 mm/Hg. Even small jumps in blood pressure numbers increase the risk of stroke and heart attack.

 

Q. Okay, so other than diet, exercise and lifestyle changes are there other natural ways or supplements I can use to lower my blood pressure?

A. Yes, in fact, you hear about some of them in the news all the time – fish oil, CoQ10, and garlic. As effective as these symptoms are, they typically lower systolic pressure much more than diastolic pressure.

However, there is a blend of scientifically and clinically studied natural ingredients that lower high blood pressure separately, and work even better when they’re combined. This combination blend contains: dandelion leaf extract, lycopene, stevia extract, olive leaf extract and hawthorn extract.

Every one of these ingredients has been studied and recommended for years. But now, a scientific study on a supplement that combines them in one synergistic formula shows encouraging results for lowering systolic and diastolic blood pressure.

Let’s take a look at each:

Stevia leaf extract	Supports healthy blood pressure levels according to clinical studies.
Hawthorn extract	Supports the heart and balance sodium and fluid levels.
Olive leaf extract	Scientifically shown to support healthy blood pressure.
Dandelion leaf	Helps reduce fluid retention
Lycopene	Clinically shown to support arteries, circulation and heart health.

 

Stevia:

Stevia (Stevia rebaudiana) originated in South America, and is often used as a sweetener. Glycosides in stevia, particularly stevoside, give the plan its sweet flavor 0 anywhere from 100 to 200 times sweeter than sugar.

The leaf of stevia is considered the medicinal part of the plant. Research shows that extracts of the leaf relax arteries and help prevent the buildup of calcium on artery walls – keeping them healthy and reducing blood pressure.

In a long-term, randomized, placebo-controlled clinical study, stevia reduced systolic and diastolic blood pressure. On average, participants’ blood pressure reduced from baseline 150 mm/Hg to 140 mm/Hg systolic and 95 mm/Hg to 89 mm/Hg diastolic.

And, in another double-blind, placebo-controlled clinical study, stevia lowered blood pressure quite significantly – by an average of 14 millimeters of mercury in both systolic and diastolic readings. Those are impressive numbers!

Despite its role as a sweetener, stevia may have a side benefit to for those with hypertension – blood sugar regulation. Scientific studies show that extracts of stevia regulated blood sugar and reduced blood pressure.

A clinical study showed that stevia extract actually improved glucose tolerance by decreasing plasma glucose levels during the test and after overnight fasting in all participants. Regulating blood sugar is very important for those with high blood pressure. When blood sugar levels are high, blood vessels are inflamed. Many people with diabetes have high blood pressure as well. In a paired, cross-over clinical study, stevioside (one of the compounds in stevia) reduced glucose levels in individuals with type 2 diabetes. Further scientific studies show that stevia works to control blood sugar levels by stimulating insulin secretion by the pancreatic beta cells. It shows great potential in treating type 2 diabetes. Further scientific studies show that stevia works to control blood sugar levels by stimulating insulin secretion by the pancreatic beta cells. Its shows great potential in treating type 2 diabetes as well as hypertension.

 

Hawthorn extract:

Hawthorn (Crataegus spp. Oxycantha) has been used since ancient ties as a medicinal herb – even being mentioned by the Greek herbalist Dioscorides, in the first century AD. Traditionally, it has generally been used for support of the heart. Modern research points to bioflavonoid-like complexes in hawthorn leaf and flower that seem to be most responsible for its benefits on cardiac health, like blood vessel elasticity.

The bioflavonoids found in hawthorn include oligomeric procyanidins, vitexin, quercetin, and hyperoside. They have numerous benefits on the cardiovascular system. Hawthorn can improve coronary artery blood flow and the contractions of the heart muscle. Scientific studies show that the procyanidins in hawthorn are responsible for its ability to make the aorta and other blood vessels more flexible and relaxed, so that blood pumps more slowly and with less effort – sparing the cardiovascular system such a hard workout.

The procyanidins in hawthorn also have antioxidant properties – protecting against free radical cellular damage.

And, hawthorn may also inhibit angiotensin-converting enzyme. Angiotensin-converting enzyme is responsible for retaining sodium and water, and may have roots in our evolutionary development. It influences blood vessel contraction and dilation, sodium and water balance and heart cell development – just about everything that has to do with blood pressure. This may have developed as a way of dealing with periods of drought and stress. By narrowing the blood vessels, the body could guarantee an adequate supply of blood and focus on repairing tissue.

Unfortunately, that can lead to real problems these days. Since many of us live in an industrialized society, and frequently have pretty sedentary lifestyles, conserving sodium just makes the conditions for high blood pressure that much worse.

Like the other ingredients in this combination, hawthorn showed benefits on other body systems, too. In clinical and scientific studies, it not only lowered blood pressure, but also showed anti-anxiety properties and regulated blood sugar.

 

Olive leaf extract:

Olive leaf (Olea europaea) comes up again and again in scientific and clinical studies as having beneficial effects on hypertension. One of olive leaf’s most beneficial compounds is oleuropein – the same compound that makes olive oil so helpful in reducing blood pressure. Here again, we have to look at the traditional Mediterranean diet, which features voluminous use of olives and olive oil. Not surprisingly, blood pressure is generally much lower in Greek and Italian populations.

But it’s not just the diet – scientific studies showed that oleuropein lowered blood pressure by relaxing the blood vessels and prevented buildup of plaque in arteries. Plus, whether in olive leaf extract or in olive oil, oleuropein works as an antioxidant, too.

 

Dandelion leaf extract:

Dandelion (Taraxacum offinale) leaves provide a healthy supply of vitamins, much like spinach. In fact, although it has become the bane of North American gardeners and lawn owners, dandelion greens are a component of many gourmet salads.

Medicinally, dandelion has been used for centuries, dating back to ancient Greece. Leaves intended for medicinal use are harvested before flowering, to ensure the most nutrients.

They are a very rich source of vitamin A, and contain vitamin D, vitamin C, carious B vitamins, iron, silicon, magnesium, zinc and manganese, too. Dandelion leaves produce a diuretic effect in the body, similar to a prescription drug. Since one of dandelion leaf’s traditional uses was the treatment of water retention, it’s really not too surprising. Dandelion leaf is also rich in potassium – one of the vital minerals many Americans lack in their diet. So, even though it may act as a diuretic, it replaces more potassium than the body expels.

The diuretic effect of dandelion can relieve hypertension by drawing excess water and sodium from the body and releasing it through the kidneys as urine. Getting rid of extra water and sodium allows the blood vessels to relax – lowering blood pressure.

 

Lycopene:

If a nutrient can be called exciting, lycopene is it. Lycopene is found mostly in tomatoes and processed tomato products, like pasta and pizza sauce. Related to beta-carotene lycopene shows great antioxidant abilities among its many talents. In fact, it shows even greater free-radical scavenging properties than beta-carotene, its more famous cousin. Healthy intakes of lycopene can guard against a variety of chronic conditions, including lowering LDL (bad) cholesterol, lowering homocysteine levels and reducing blood platelet stickiness that can lead to clogged arteries. It’s even being studied for its protective effect against prostate cancer.

And, for proof, you don’t have to look too far to see the amazing effect lycopene intake can have on health. The Mediterranean diet provides an excellent example. Its high intakes of vegetables, (tomatoes, of course, playing a central role) fish, and whole grains improve cholesterol levels and lower blood pressure. The research on lycopene as a stand-alone nutrient has been compelling. A randomized clinical trial found that not having enough lycopene was associated with early thickening of the arteries.

So, it makes sense that other clinical trials, showed that higher intakes of lycopene frequently meant less thickening of arteries, and a reduced risk of heart attack. In one study, the risk of heart attack was 60% lower in individuals with the highest levels of lycopene. In a multicenter study, similar results were found – men with the highest levels of lycopene had a 48% lower risk of heart attack.

 

Q. What can I expect taking this herbal combination?

A. You should notice both systolic and diastolic numbers lowering in about two weeks. The scientific study showed that for pre-hypertensive and stage I, (early hypertensive individuals) this combination for ingredients lowers both systolic and diastolic blood pressure.

When you’re taking herbs to support your blood pressure, it’s important to keep it monitored so you have an accurate reading (and record) of your numbers. If you need to, you can pick up a home blood pressure monitoring device. These can retail for anywhere from $30 all the way up to $200, but buying one in the $30 to $50 range is a good idea and money well spent. Consider taking the machine to your local doctor’s office or fire department to have it tested for accuracy against a professional blood pressure monitor. See the chart below for tips on getting an accurate reading from a home monitor.

 

Tips for Accurate Blood Pressure Monitoring:

-Relax for about 5 to 10 minutes before measurement.

-If you have just come inside from cold outdoors allow yourself to warm up.

-Remove tight-fitting clothing and jewelry.

-Unless your physician recommends otherwise, use left arm to measure pressure.

-Sit, don’t stand.

-Remain still and do not talk while using the monitor.

 

Q. Are there any side effects?

A. There were no side effects noted in the study. However, because of the mild diuretic effect of dandelion leaf extract, you may notice an increase in trips to the bathroom. It’s always important to make sure you don’t get dehydrated, so you may want to drink more water during the day.

 

Conclusion:

High blood pressure doesn’t happen overnight. As we get older, the likelihood of developing hypertension increases. And, stressful, fast-forward lifestyles, bad diets and no exercise conspire to raise our blood pressure.

 

In my own practice I have helped patients move toward a healthier lifestyle, including diet, exercise, and blood-pressure reducing supplements. They live better, more vibrant lives as a result, and their blood pressure normalizes. It really can happen – you can bring your blood pressure back to normal, and this combination of scientifically and clinically validated ingredients can help.