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Search Term: " quinone "
What Cellular Mitochondria Does in the Body   
Date:
April 28, 2022 04:19 PM
What are mitochondria and what do they do in the body Mitochondria are organelles that play an important role in the energy metabolism of cells. Most of the oxygen we breathe is used by mitochondria to convert glucose from the food we eat into ATP, the energy molecule used by our cells. Therefore, mitochondria are often referred to as the "powerhouses" of the cell. In addition to producing ATP, mitochondria also have other important functions, such as regulating cell growth and death, as well as calcium homeostasis. Mitochondria are unique in that they have their own DNA separate from the DNA in the cell nucleus. This mitochondrial DNA is passed down from mother to child, which is why defects in mitochondrial function can lead to diseases that are inherited in a maternal lineage. Although most of our cells contain only a single nucleus, they may contain hundreds or even thousands of mitochondria. This allows them to produce enough ATP to meet the energy needs of the cell. How mitochondrial dysfunction can lead to health problems Mitochondria are integral to many essential physiological processes in the body. Not only do they produce energy for cells, but they also play a key role in maintaining cellular structures and initiating cell division. Therefore, any disruption of normal mitochondrial function can have far-reaching consequences for overall health and well-being. Maladaptive responses to environmental stressors, such as chemical exposure or radiation, are among the most common causes of mitochondrial dysfunction. These stressors result in damage to mitochondrial DNA and can cause problems with cell division and abnormal growth patterns, which can lead to a range of disorders and chronic diseases. For example, mitochondrial dysfunction has been linked to conditions like Alzheimer's disease and type 2 diabetes, as well as cardiovascular disease and cancer. Therefore, it is important to understand the role that mitochondria play in maintaining healthy functioning bodies and take proactive steps to prevent or reverse damage from maladaptive responses to environmental stressors. Mitochondria and Longevity Mitochondria are specialized organelles found within our cells that perform many critical functions, including generating energy to support cellular processes and maintaining healthy cell function. These organelles are the site of many important chemical reactions, often referred to as oxidative phosphorylation or metabolism. Studies have shown that Proper functioning of these organelles is essential for healthy aging, and may be a key factor in determining how long we live. By promoting mitochondria health and making lifestyle changes that help to promote healthy mitochondria, we can take an important step towards optimizing our longevity potential. This includes eating a nutrient-rich diet with a focus on foods high in antioxidants, managing stress levels through regular exercise and relaxation techniques, and avoiding environmental toxins that can damage mitochondria health. Through such strategies, we can give ourselves the best chance at living a long, full life. Ways to protect your mitochondria and keep them healthy with PQQ PQQ, or pyrroloquinoline quinone, is an important molecule for the functioning of mitochondria in the human body. This compound plays a crucial role in adenosine triphosphate (ATP) synthesis, the fundamental energy currency of biological systems. By driving cellular processes that release energy for metabolic use, PQQ plays a key role in maintaining mitochondrial health and efficiency. Additionally, PQQ has been shown to exhibit powerful antioxidant properties, which help to mitigate the effects of oxidative stress on mitochondria and other critical cells in the body. Overall, PQQ is an essential component of healthy mitochondrial function and a crucial nutrient for energy production and overall metabolic health. D-ribose, the Mitochondria, and Energy D-ribose is a naturally occurring sugar that plays an important role in cellular metabolism and energy production. This nutrient is especially important for cells that rely on a lot of energy, such as those found in the heart and muscles. D-ribose helps these cells to generate adenosine triphosphate, or ATP, which is the main energy currency used by cells to drive chemical reactions. Additionally, research has suggested that d-ribose can help to improve physical endurance and reduce the pain and stiffness associated with exercise, making it an important part of a healthy, active lifestyle. Also, D-ribose is a simple sugar that plays an important role in the structure and function of mitochondria, the powerhouses of the cell. In addition to supplying energy to the cells, mitochondria also help to regulate cell growth and death. D-ribose is essential for the proper function of mitochondria, and it plays a key role in energy production. Studies have shown that D-ribose can help to improve mitochondrial function and reduce fatigue. In addition, D-ribose supplements have been shown to improve exercise performance and increase energy levels. These effects are likely due to the ability of D-ribose to help the body produce more ATP, the energy currency of the cell. For these reasons, D-ribose is an important nutrient for maintaining healthy mitochondria and supporting cellular energy production. Another important nutrient for the mitochondria is CoQ10 The process of producing energy is called oxidative phosphorylation, and it involves the transfer of electrons from nutrients to oxygen. This reaction creates a proton gradient across the mitochondrial membrane, which is used to generate ATP, the energy currency of the cell. Coenzyme Q10 (CoQ10) is an important component of this process. It acts as an electron carrier, shuttling electrons between enzymes in the respiratory chain. It also helps to maintain the proton gradient, allowing the mitochondria to continue generating ATP. Without CoQ10, oxidative phosphorylation would grind to a halt, and cells would quickly run out of energy. Consequently, CoQ10 plays a vital role in energy production and cellular metabolism. The bottom line is that both D-ribose and CoQ10 are important nutrients the body needs to maintain optimal energy levels. If you’re feeling run down, low on energy, or just generally not your best, consider taking a supplement containing these two nutrients. You may be surprised at how much better you feel once you start including them in your diet. What’s stopping you from giving them a try?
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6395) Coenzyme Q10: Research confirms ubiquinone and ubiquinol are nearlyequally-absorbed ... 
Date:
April 22, 2019 04:29 PM
Many Coenzyme Q10 products have labels that indicate that their product is better absorbed due to longtime beliefs surrounding ubiquinol (reduced Coenzyme Q10) being hard for the body to absorb. Many brands instead market ubiquinone, which is redox Coenzyme Q10 instead, since studies have been more supportive about this form being easier for the body to absorb. New research, however, is concluding that both of these forms are equal when it comes to the ability to be absorbed through the body. Key Takeaways:
"Marketing terms such as “better absorbed” should be questioned unless the absorption or bioavailability is actually stated. Only when the actual absorption has been verified can the better absorbed product be determined." Read more: https://wholefoodsmagazine.com/columns/vitamin-connection/coenzyme-q10-research-confirms-ubiquinone-and-ubiquinol-are-nearly-equally-absorbed-compounds-the-physical-form-and-companion-ingredients-make-the-bioavailability-and-absorption-difference-in-coenz/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6152) What are the health benefits of aloe vera juice?
Date:
February 16, 2019 08:57 AM
The aloe vera plant has long been used for its medicinal purposes but now there is a new way to enjoy the amazing benefits this plant has to offer. Have you had your aloe vera juice for the day? If not, it's time to pour a nice glassfull. Drinking aloe vera juice offers a slew of health benefits, which include high levels of vitamin C that the body needs, prevents and cures constipation, and so much more. Key Takeaways:
"Vitamin C has a variety of specific benefits, from reducing a person's risk of cardiovascular disease to improving immune system function. Getting enough vitamin C also enhances the body's ability to absorb iron from plant-based foods." Read more: https://www.medicalnewstoday.com/articles/324072.php
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6034) Zinc can protect against oxidative stress when it's taken togetherwith chocolate and tea
Date:
February 08, 2019 03:48 PM
As human cells burn energy in their processes, they give off "exhaust", if you will(cellular expiration), which can cause damage to components of the cell and surroundings. One of the byproducts in this respiration is superoxide, which may have a role in the aging process and other degenerative problems. However, there may be a metal that may help without hurting: zinc. And, some reseachers say, taking zinc with items such as chocolate or wine may enhance the process zinc has in breaking down the superoxide. Key Takeaways:
"A study published in the journal Nature Chemistry suggests that the nutritional benefits of zinc can be bolstered when combined with a natural compound found in chocolate and tea." Read more: https://www.naturalnews.com/2019-02-04-zinc-protects-against-oxidative-stress-with-chocolate-and-tea.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6011) Study: PQQ (pyrroloquinoline quinone) may prevent and even reverseAlzheimer's
Date:
January 04, 2019 08:12 AM
Pyrroloquinoline quinone (PPQ) is a microbe that is derived from plants, and it is showing to have neurological benefits that are associated with the prevention of Alzheimer's progression. This particular microbe is able to reduce inflammation in the brain, which can lead to several neurological conditions. It also helps patients in post-stroke recovery because it is able to reduce the area of the brain that is impacted by stroke activity. Most importantly, it helps in the prevention of Alzheimer's due to how it can neutralize levels of oxidative stress. Key Takeaways:
"Glutamate is an important chemical in the brain, but too much of it results in excitotoxicity, a risk factor in both stroke and neurodegenerative disease. PQQ protects the brain from overstimulation by glutamate and the resulting death of brain cells." Read more: https://www.naturalnews.com/2018-12-15-ppq-can-prevent-alzheimers.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5928) PQQ is effective in combating neurodegeneration that can affect theaging brain
Date:
December 21, 2018 08:53 AM
A nutrient called Pyrroloquinoline quinone (PQQ) has shown potential for combating the degenerative neurological symptoms of Alzheimer’s, according to research published by Life Extension. Mice that were given a PQQ supplement developed smaller deposits of toxic proteins in their brains compared to the mice that did not, and also demonstrated better recall, memory, motor skills and learning relative to the control group. Other research suggests PQQ may help with Parkinson’s symptoms, and improve blood circulation within the brain. Key Takeaways:
"But there are many ways in which a person can reduce their risk of neurodegeneration as they age, like healthy eating." Read more: https://www.naturalnews.com/2018-12-13-pqq-combats-neurodegeneration-that-can-affect-the-aging-brain.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5916) 10 Toxic skincare product ingredients to watch out for
Date:
September 26, 2017 12:14 PM
There are lots of choices in products to take care of your skin. Some are better than others, there are even ingredients that you shouldn't use on your skin. Here are some examples of things you should look for in the ingredients of your products: Certain color pigments that can cause your skin to be irritated; Hydroquinone, which can various skin diseases and even cancer; parabens can cause problems with the reproductive system; mineral oil will clog pores and keep your skin from cleaning itself out. These and other ingredients are used to make more and cheaper skincare products. Key Takeaways:
"Synthetic fragrances are considered to be one of the top allergens in beauty and skincare products." Read more: http://www.naturalnews.com/2017-09-18-10-toxic-skincare-product-ingredients-to-watch-out-for.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5282) The Many Benefits of Black Seed Oil
Date:
April 25, 2017 08:44 AM
Have you heard about black seed oil? This is becoming quite popular in the natural diet realm. Did you know that black seed oil is great for sunburns and for overall skin care? It also will help strengthen your hair that is damaged by heat. In addition to this, black seed oil is also great for cardiovascular health and has a lot of benefits to strengthen the heart. Finally black seed oil can work as a natural pain reliever. It help to moderate the pain just as well as a Tylenol. Key Takeaways:
"This ancient flower found predominantly in the Middle East possesses benefits that far exceed those found in any other substance in nature. In fact, oil of black seed is so unique in its abilities that by taking it daily it can help with cardiovascular health, respiratory response, inflammation, pain, digestive system, skin and hair, to name a few." Read more: http://www.wholefoodsmagazine.com/blog/many-benefits-black-seed-oil/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4473) Oregano Plant Is the Most Potent Antimicrobial In The world
Date:
November 15, 2016 07:24 PM
Along with its culinary usage, oregano shows antimicrobial and antioxidant properties and possess probable activity like an antispasmodic and in diabetes. But there is no clinical proof to facilitate the usage of oregano in any signs. Normal or wild oregano is a perennial plant grown in the Mediterranean region and Asia. It is also cultivated in the United States. The creeping rootstock of oregano makes a downy, square, purplish stem with reverse ovate leaves. The plant stem also grows about 76cm tall. Purple two lipped flowers develop in terminal groups from July to October. Features of OreganoThis plant has been a normal ingredient in Italy, Spain and Italian dishes like a spice and flavouring compound for several years. Its basic purpose was like a cautious digestive and circulatory stimulant. This plant has been availed in perfumery for the volatile oil materials, particularly in scenting soaps. The antiseptic feature of medicinal and aromatic plants and the extracts have been identified since antiquity. It has been recommended that an infusion of the new herb is useful in treating a collapsed stomach and indigestion, colic, headache and nervous problems as well as for some respiratory ailments. A mixture of the flowers has been utilized to avoid seasickness. Uses of OreganoThe oil of this plant has been availed externally in lotions and liniments and to ease toothache. Oregano has been utilized like an ant repellent. Oregano has ursolic and oleanolic acids, hydroquinones, flavonoids, rosmarinic, caffeic,tannins, lithospermic acid and phenolic glycosides. The compounds of phenolic represent seventy one percent of the full oil. The carvacrol and polar phenols thymol are accountable for several of the properties of the necessary oil as well as terpinene and P-cymene. Research has compared the impacts of oregano necessary oil, carvacrol and thymol on fungi. All three totally reduced fungal development of aspergillus and penicillium species. The oil also seems to possess certain activity against Candida species, probably due to the reason of its carvacrol content. The oregano volatile oil have explained in vitro antibacterial activity against different types of gram negative and gram positive microorganisms like pseudomonas, listeria, salmonella, proteus and clostridium species as well as certain methicillin resistant. There are different reports explaining antiparasitic activity of oregano. The origanum vulgare oil has been presented to remove normal parasites in pheasants and chickens. There are also some other Potent Antimicrobial seen in the world like clove, cinnamon, nutmeg, onion, garlic, anise, sassafras, ginger. These all have certain amount of antimicrobial properties in it. Related Products
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3451) Black Seed Oil Health Benefits
Date:
September 30, 2015 09:52 PM
Black seed oil is derived from black cumin seeds. Black seeds, also known as black cumin seeds, black caraway or kalonji have been used medicinally since ancient times. In cooking, they are added as a whole for flavoring dishes. The seeds come from the annual flowering plant, Nigella sativa, which is indigenous to Asia. Just like the seeds, black cumin seed oil is highly prized for its culinary and therapeutic applications. Black seed oil is a multivitamin loaded with nutrients. It contains Iron, Zinc, Potassium, Calcium, Magnesium, Linoleic acid, Selenium, Oleic acid and vitamins A, B, B2 and C. This light brown oil is slightly bitter and has a mildly pungent aroma. Possessing antibacterial and anti-inflammatory properties, this oil is effective in treating many external and internal health problems.
Here are some benefits of Black Seed Oil:
The nigellone in black seed oil helps open up the lung’s air passages and makes a person breathe easier. This oil is thus considered effective against respiratory problems. The oil can be used internally and externally to fight problems like cough, bronchitis and asthma.
Nigella sativa can be used to treat several skin problems due to its anti-inflammatory properties. Acne sufferers can mix the oil with honey and use it as an acne treatment mask. The oil helps renew cells and heals acne scars. Apart from this, it can also be used to treat fungal infections. Since skin infections are caused by bacteria and fungus, this oil can be used to treat many skin infections.
Pure oil extracted from black seeds can be added to routine hair and nail care regimen. The vitamins present in this oil helps improve hair texture and strengthen hair the natural way. Some of the improvements can also be observed in nail health.
The carminative action of black seed oil makes it an excellent remedy for reducing bloating and other digestion problems. Adding this oil in your cooking is a simple way to combat indigestion and excess gas formation.
This oil contains thymoquinone, a powerful antioxidant that helps flush out toxins from the body. Regular consumption of this oil can help improve your general health.
References //draxe.com/black-seed-oil-benefits/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3225) What Is Thymoquinone Found In Black Seed Oil?
Date:
September 28, 2015 08:53 PM
The black seed oil is obtained from the seeds of the Nigella Sativa plant. The black seeds, also known as the black cumin, were used by the ancient Egyptians because of their ability to cure a variety of health conditions such as toothaches, headaches. It was also used as a dietary supplement. Additionally, the black seed oil is effective in ensuring a stable immune system as well as combating diseases that affect the immune system. The medicinal power of this oil emanates from its active ingredient, thymoquinone. Thymoquinone is an active compound that contains anti-inflammatory, anti-cancerous, and antioxidant properties. Research indicates that thymoquinone can thwart the cancerous cells in the colon, pancreases, and prostate. Because of the healing properties of this compound, black seed oil, therefore, remains useful as far as human health is concerned.
Some of its benefits includes:
The black seed oil has been used for a long time to treat cancer. According to the research from three Chinese researchers and four Arabian scientists, black seed oil contains the right anti-cancer properties. They noted that the black seed oil was used as a traditional medicine for many years. The active compound, thymoquinone, contained in the black seed oil is effective against many other diseases such diabetes, kidney, asthma diseases.
Taking a teaspoon of the black seed oil can help cure fever or flu. It causes the body to sweat for it to recover from the illness.
Research indicates that black seed oil can help a person sleep well if suffering from insomnia. One teaspoon of the oil put in a warm drink before sleeping helps to eradicate the problem.
Studies show that the black seed oil responds positively to the treatment of Rheumatoid arthritis. Further studies indicate that this oil helps reduce inflammation in the joints and the stiffness that occur in the morning.
Black seed oil is an anti-bacterial and anti-inflammatory, and it is ideal for treating coughs and also addressing asthma symptoms. It achieves this by relaxing the bronchiole tube muscles.
According to researchers from Turkey, black seed oil is potentially helpful to people receiving radiation treatment for cancer. The thymoquinone compound in black seed oil makes this oil essential to the health of human beings. Consumption of the black seed oil will keep you off from most cancer infection and diseases.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3224) What Are The Benefits Of Ubiquinol Vs Regular CoQ10?
Date:
May 31, 2014 06:33 AM
In modern society, nutritional supplements have become a common method to improve health. A wide range of specific needs determines the use of different supplements, but there are a few that will work in just about everyone and improve their health. Coenzyme Q10, commonly abbreviated to CoQ10, is one of those universally effective supplements. This vitamin-like substance offers far-reaching benefits for the human body. It has a crucial role in the body's energy maintenance and it's an extremely powerful antioxidant. This substance is naturally produced by the body, but as we get older, the organism's ability to synthesize CoQ10 weakens progressively. It is, therefore, recommended that people initiate a regular intake of CoQ10 somewhere at the adult or even young adult life stage. This is a commonly prescribed supplement for old people owing to its longevity and energy inducing benefits, but it's especially critical for those who are medicated with statin drugs because these are known to reduce CoQ10 levels in the organism. Elite athletes can also benefit from this substance to achieve higher peak power levels. Ubiquinol is the most efficient way to take advantage of this supplement because it's the fully reduced form of CoQ10 that our body actually absorbs and uses. The consumption of Ubiquinone requires our body to firstly metabolize and convert it into Ubiquinol. This process limits the speed and efficiency of CoQ10 absorption, requiring larger quantities to be consumed for similar health effects, not to mention that the metabolism has a tendency to worsen with age. Ubiquinone is more widely available and is cheaper, though.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3129) Does Ubiquinol Get Absorbed Better Than Regular CoQ10
Date:
November 06, 2013 08:52 PM
Benefits is Ubiquinol Ubiquinol can be described as reduced form of CoQ10 (Ubiquinone). For an individual to benefit from the type of nutrient that is needed for producing cellular energy and reduce signs of aging, the body has to convert ubiquinone to ubiquinol. Studies have shown that it gets absorbed better than CoQ10. It is also known to reduce exercise induced fatigue by around 90% when compared with Ubiquinone. This is probably because CoQ10 has a chemical nature that undergoes “redox chemistry”. This implies that it flips back and forth between not having and having two additional electrons. Importance of Ubiquinol to Human Body This is a very important part of the human body because it transports flow of electrons that permits chemical energy to be harnessed down a gradient. This is normally the last stage where food is converted to energy to fuel the body. Ubiquinol on the other hand is the form where these extra electrons are reduced when speaking in chemistry terms. Although there is a small difference between the two, it really has big implications as this is exactly what makes it to be more absorbable in the intestines. In addition to this, the body prefers this form to perform the transport function of the blood. It is important to note that Ubiquinol was introduced to the market when Kaneka discovered techniques on how to stabilize the ingredient in 2006. From then, it has become an ingredient in numerous products. Various findings also show that it is the preferred form when it comes to ingestion. There are some studies that also show that this form is beneficial for patients who are suffering from advanced stage cardiac disorders. This is because it is absorbed much easily and also shows potential for greater clinical benefit. Manufactures are also looking into new and more advanced methods that will be used to make sure that it can be absorbed more easily than before. References:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2880) What Is Ubiquinol?
Date:
August 23, 2013 02:54 PM
Coenzyme Q10 (Co10) is a naturally-occurring chemical compound in the body which fuels cell growth and enhances enzyme functions. It exists in three forms; ubiquinone (fully oxidized), semiquinone (partially reduced), and ubiquinol (fully reduced). So, ubiquinol is basically a reduced form of Co10, it is a strong antioxidant that can neutralize free radicals. Free radicals refer to a reactive and unstable atom that can trigger many medical conditions such as cardiovascular issues, weak immunity and even cancer.
Ubiquinol is found in almost every organ, tissue and cell in mammals. This lipid-soluble benzoquinol can be acquired through supplementation, biosynthesis and from diet (in small amounts). Ubiquinol plays an integral role in transferring electrons within the body, thereby leading to ATP synthesis. The antioxidant property of ubiquinol is very essential in the functioning of the cellular systems.
Ubiquinone is naturally converted into ubiquinol by the body to produce energy for the cells. The failure of this process can lead to insufficient energy levels in the body. The ability of the body to generate Coenzyme Q10 reduces with age and so does the ability to convert ubiquinone into ubiquinol. Therefore, older people should use ubiquinol supplements to boost their energy levels. Apart from older people, those who suffer from neurological, cardiovascular, diabetes and liver conditions may also have low ubiquinol levels.
There are many health benefits associated with ubiquinol. First, it offers a sufficient amount of energy which the heart needs to work well. It's also a strong antioxidant that protects the heart, and other vital body organs from free radicals. When it comes to energy, ubiquinol is an essential component in 95 percent of the energy produced in the body. Daily intake of ubiquinol supplement can help reduce fatigue and muscle pains; the common symptoms of insufficient Coenzyme Q10 in the body. Since ubiquinol is a strong fat soluble antioxidant, it can protect the body from oxidation, thereby providing an anti-aging benefit. Do you feel fatigued, run down with no energy? Consider Ubiquinol as a natural safe energy boosting supplement.
References
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2850) Why Is Acai, Goji, Pomegranate, Noni And Mangosteen Called Super Fruits?
Date:
January 15, 2013 04:55 PM
Health Benefits Of Super Fruits "Super fruits" is an idiom that is frequently used to refer fruits that have extraordinary antioxidant and nutrient qualities and provides benefits over and above the basic nutrition. Exotic fruits such as acai berries, goji berries, mangosteen, noni and pomegranate have earned this distinguished status. These fruits have exceptional amounts of vitamins, antioxidants and phytochemicals that play a significant role in preventing various diseases. Each of these super fruits restrains its own distinctive set of properties that prove to be extremely beneficial for the overall health of the body. Health Benefits Associated With Super Fruits: Acai Berry: Acai berry is a rich source of dietary fiber, protein and a compound called anthocyanins. It also includes high levels of omega-6 as well as omega-9 fatty acids, which are believed to have a protective effect on the cardiovascular system and heart. In addition, the anthocyanins compound present in the acai berry helps in lowering the blood cholesterol level. Mangosteen: This fruit is abundantly grown in south Asian and due to its fine flavor it is also referred to as "The Queen of Fruits". Mangosteen retains high levels of phytochemicals known as xanthones that offer this fruit a unique medicinal property which is not found in other common fruits. Mangosteen also includes other powerful natural compounds such as polysaccharides, catechins, quinones, polyphenols and stilbenes. Each of these compounds are believed to be effectual in preventing diseases such as, osteoporosis, atherosclerosis, high blood pressure, kidney stones, glaucoma, cataract, Alzheimer's, neuralgia etc. The fruit is also used to treat aging, depression, obesity, allergies, skin diseases, ulcers, fevers, diarrhea and pain. Noni: Noni juice is known to restrain more than 150 nutrients, including protein, all the essential amino acids, vitamins A, B1, B2, B3, C and E, minerals such as iron, calcium, magnesium, selenium and potassium, polysaccharides, phytonutrients and digestive enzymes. Noni is one of the most unique super fruits. Noni juice can help to normalize blood sugar levels; decrease inflammation, arthritis and joint pain; enhance digestive function, cleanse colon, remove parasites; reduce irritable bowel syndrome, diarrhea, constipation and menstrual cramps; prevents gastric ulcers; relives pain, mental depression and atherosclerosis. Goji Berry Juice: This miraculous berry is rich in polysaccharides. It also includes fiber, 18 amino acids, 21 minerals, Vitamins A, C, B, & E, protein and Omega-3 and Omega-6 fatty acids. Goji juice is a potent antioxidant that prevents premature aging. It also stabilizes molecules called free radicals that damage the DNA and gives rise to several diseases. Moreover, Goji juice helps in reducing the risk of cancer by averting DNA mutation, curtailing growth of tumors and by managing the peroxidation of lipids. This distinctive fruit helps to relieve insomnia and headache, improve functions of the heart, assist in digestion, aid to regulate weight, promote sexual health, improve fertility, enhance memory functions, and alleviate dry cough. Pomegranate: Pomegranate is one of the oldest known super fruits. It is rich in vitamins A, B and C, potassium, magnesium, phosphorous, calcium and sodium. Pomegranates are very high in dietary fiber which boosts the digestive system. Additionally, medical evidences reveal that a unique amalgamation of polyphenols found in pomegranate helps to lower LDL or bad cholesterol in the blood which eventually benefits the heart. Moreover, pomegranate's natural antioxidant and anti-inflammatory properties aid to slow down the development of cancer especially, prostate and lung cancer. Overall, super fruits are extremely valuable for our body due to its high anti-oxidant and nutrient content that helps to reinforce the body's natural defenses and make it healthier and less prone to most type of diseases.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2812) Why Is George's Aloe Vera By Warren Labs Better Than Other Brands?
Date:
January 10, 2013 12:50 PM
Since time immemorial, the succulent Aloe Vera plant has been an eminent medicinal plant with a worldwide recognition. The soothing effect, rejuvenating irritated membranes, moisturizing the skin and easing constipation have been some of the undisputed health benefits that makes Aloe Vera gel a worthy supplement and cosmetic product's constituent. Recent research also shows that Aloe Vera extracts have a notable efficacy in lowering blood glucose and blood lipid levels. Studies however depict that the varied Aloe Vera species differ in some biochemical constituents and composition which makes some species better than others for a specific use. Georges Aloe Vera produced by Warren Labs specifically selects the species that are best suited for a given use. For instance, their George's Always Active Aloe Vera drink is made from Aloe barbadensis species which has been noted to be the most beneficial in rejuvenating mucal membranes that lines the GIT, effectively eases and prevents constipation without any irritation and also lowers blood lipid levels. Unlike other manufacturing processes employed by other Aloe supplement producers, George's Aloe Vera employs fractional distillation method to obtain the most beneficial constituents and gives Georges Aloe Vera drink the characteristic clear and thin feel. This process is primarily intended to get rid of the Aloe Vera's aloins and anthroquinones which irritate the GIT manifested by cramping and diarrhea. The distillation process also makes the drink easy to preserve since most of the Aloe Vera's constituents which may necessitate special storage or addition of additives are discarded off. This yields a pleasantly tasting drink with no additives or preservatives added. For optimal health benefits of this supplement, the manufacturer recommends a consistent daily intake of 2 ounces twice a day, and thus a gallon pack is always enough to use for a month. However, even though most of the Aloe Vera's constituents which produce considerable drug interaction implications are distilled off, consulting your doctor before using the supplement while under medication is always worthwhile.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2808) Coq10 and its benefits
Date:
October 26, 2012 11:04 AM
CoQ10 We insist that vitamins and essential nutrients should be an essential part of our daily diet. But are we aware that some vitamins and chemical nutrients are also created naturally in our bodies? One such essential compound is known as Coq10. Found in most living organisms, Coq10 also known, as ubiquinone is a chemical that boosts the levels of energy produced in the body. It monitors the functioning of the mitochondria and cells that are useful for metabolizing the fat in the body. Without the presence of this essential compound, there could be some serious problems. Here are its respective virtues for people. Heart And Muscle Repair Scientific studies have proved that the enhanced production ofCoq10 has helped to solve some major health issues for people. The enhanced production of the compound was instrumental in strengthening the muscles and tissues of the heart. This meant that adequate levels of Coq10 help to reduce the congestion in the heart and veins. Also, the presence of this ubiquitous compound will also help in getting respite from muscular dystrophy. Also, those, who are vulnerable to breathing problems and arrhythmia, can also find a solution through such a compound in their bodies. Immunity And Blood Pressure Those, who have the problem of high blood pressure, would be advised to eat more of things like fish or meat as these contain Coq10 in good amounts. Adequate levels of this chemical will aid in reducing the levels of blood pressure and improving the circulation of blood in the body. Also, Coq10 is known for improving the person's immunity against the common degenerative diseases as well as cancers and malignant tumors and so on. Thus, it can be safely said that Coq10 is a powerhouse of nutrients that help to keep disastrous afflictions at bay. You should have more of it.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2694) What Are The Health Benefits Of Cascara Sagrada?
Date:
October 09, 2012 08:37 AM
Cascara sagrada is considered to be a herbal tree which is famous for its laxative properties. Aside from this fact, there are other health benefits of this herb. Read on and find out more about the benefits of this deciduous shrub. The Health Benefits of Cascara Sagrada 1. This particular herb is famous in treating chronic constipation. It does not provide fiber; it irritates the lining of the bowels as well as increases the rate of digestion. Dried and aged barks of this herb are used in treating chronic constipation. This herb contains hydroxyanthraquinone glycosides called cascarosides which induces the large intestine, thus increasing muscular contraction. 2. Another health benefit of this herbal shrub is its detoxifying properties. It is believed that the formation of toxic materials in the colon can cause colon diseases. Good thing this herbal shrub can help in cleansing and restoring the natural tone of your colon. 3. Aside from the ones mentioned above, Cascara Sagrada is also known to increase the secretions from pancreas and liver. With this, it will promote overall health and wellness when it comes to your digestive system.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2680) What Makes Ubiquinol The Best Form Of COQ10?
Date:
March 08, 2012 11:48 PM
Benefits of Ubiquinol Ubiquinol is an active antioxidant form of CoQ10. It is pre-converted and ready-to-use diet supplement. Hence, it is easily absorbed and utilized by the body. Research studies show that ubiquinol has proved to be much more effective than ubiquinone and has all vital health benefits as CoQ10. Ubiquinol is the next generation supplement which provides support for a healthy body and mind. It helps you to live a healthy life by raising your CoQ10 plasma level. It also plays an important role in production of energy levels. Moreover, it protects the cells of the body from oxidative kind of stress which can eventually damage proteins, DNA, and lipids. Benefits of Ubiquinol: Cardiovascular health: Clinical studies show that ubiquinol improves the overall cardiovascular health. Cardiac patients who have been taking high dosages of statins like Lipitor, Zocor, etc for a long period of time have decreased levels of coenzyme Q10 as these statins inhibit the body's production level of coenzyme Q10. The low levels of CoQ10 in the body can result in cardiomyalgia, fibromyalgia, atherosclerosis, etc. Thus, if these patients take ubiquinol which is an antioxidant then it neutralizes the oxidation of LDL. Cognitive Health: It helps to increase the stamina and energy and promotes general health and wellness. Anti-aging support: Due to degeneration and advanced age, the aged people have less CoQ10 biosynthesis and body's conversion ability also diminishes in such subjects. A collaborated study carried out on middle aged people demonstrated that subjects who were given this supplement showed marked improvement in their physical and mental activities. Thus ubiquinol by and large promotes life extension and improves the overall mental health by compensating for the age-related conversion disability. Power to other organs: Ubiquinol plays an important role in igniting energy levels within the cells of vital organs like heart, kidneys, liver, and lungs. Thus it naturally helps you to sustain your energy levels. Protects Cells: Ubiquinol protect cells of vital organ like heart from further damage and from constant attack by free radicals. Neuronal Health: Ubiquinol benefits the neurological system and promotes brain health. Studies carried out on patients who had Parkinson's disease have proved that it reduces the functional decline in these patients. Oral Health: Ubiquinol impacts the oral health and significantly enhances the salivary coenzyme Q10 levels. It affects all aspects of mouth, teeth, lips, tongue, and salivary glands. Renal Health: Studies show that Ubiquinol gives significant renal protection to patients who have chronic kidney disease. Your body constantly produces powerful antioxidants daily when you are young. But as you age, your body can not sustain this natural production level forever. Hence ubiquinol supplementation is important to promote overall good health. Ubiquinol can be used as a dietary supplement. Its ready-to-use formula is eight times more effective as it can be readily absorbed by your body. Thus it is an ideal diet supplementation for current CoQ10 users.
At present there are no known side effects of ubiquinol, but if you are on multi-drug therapy or are already taking other supplementations, then please consult your doctor prior taking this diet supplementation Ubiquinol.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2605) What is Vitamin K Good For?
Date:
February 15, 2012 10:05 PM
Understanding Vitamin K Vitamin K can be found in different forms, Phylloquinone is vitamin k1 and it is found in plants. Vitamin k2 is referred to as Mena quinone and is produced by the intestinal bacteria. It can also be obtained from purified fish. The synthetic version of this mineral is called Menadione. The role of the mineral is to aid in the blood clotting functions. When there is a deficiency, the production of prothrombin and various clotting factors is reduced. With time a person begins showing signs of hemorrhage. The human body is incapable of synthesizing the mineral so you need to get it from dietary sources. The intestinal bacteria produce it as a metabolic by product. It is hard for someone to suffer from a deficiency since the vitamin is available from so many sources. Vitamin K Stability Since it is water soluble and heat stable there is no risk of leeching or inactivation during cooking. However, strong acids and alkalis have a destructive effect on the substance. Even though gamma irradiation is used to prolong the shelf life of food it inactivates the mineral. Bile has to be present in order for the vitamin to be absorbed by the body. Lipoproteins in the bloodstream are responsible for transporting it to the liver. When it gets to the liver it is in is inactive form. A reductase is needed in order to revert it into its active state. How Vitamin K Is Made Normal intestinal bacteria are usually destroyed by prolonged use of antibiotics. This means that the body is unable to synthesize the mineral. The patient is put on supplements so as to prevent hemorrhagic tendencies. When a person is taking the supplements they are administered via intravenous or intramuscular injections. In some cases people are asked to take the supplements orally. During the first weeks of their lives babies can suffer from hemorrhagic conditions due to a deficiency in vitamin k. in order to prevent this from happening, the infants are routinely injected with natural minerals at the time of birth depending on their weight. Medical practitioners do not use the synthetic version because it is toxic to babies. Deficiency, Symptoms A person suffering from a deficiency of vitamin k has certain symptoms such as excessive bleeding, less active prothrombin in their blood, their blood takes long to clot and if they are newborns they suffer from hemorrhagic episodes. There are a number of medical conditions and treatments that can cause a deficiency. If you have a medical condition that interferes with the absorption of fats in the intestines then you could suffer from a deficiency of vitamin k. some of the conditions that lead to the problem include obstructive jaundice, ulcerative colitis, gallbladder disorders and diarrhea. When you have any one of these conditions your body is unable to absorb the vitamin. You can also suffer from a deficiency if you use mineral oil as laxatives. The vitamin usually attaches itself to the oil droplets in your intestines instead. The body is unable to absorb it so it is excreted in the feces. People are usually discouraged from using mineral oil to cure constipation because of this reason.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2578) Can I Use Senna Leaves As A Laxative Daily?
Date:
September 27, 2011 12:52 PM
What Are Senna Leaves Good For? Senna is a plant which belongs to the family of flowering plants known as Fabaceae. This plant can be abundantly found in tropical regions. This plant is considered to be a shrub. However, some seemingly looks like an herb or a small tree. Senna is one of the most commonly used herbal laxatives. Other names of Senna are Cassia Senna, Tinnevelly Senna, India Senna, Alexandrian Senna, and Khartoum Senna. The active ingredients of Senna are called Anthraquinone and glycosides. As a laxative, the active chemical in Senna acts primarily on the large intestine, therefore, this herb has a promising effect in relieving constipation. Clinical studies have also reported that Senna can enhance peristaltic movement of the intestines. This is possible because of its irritating effect on the mucosal lining of the intestines. To be specific, Senna is an effective laxative. It is categorized as a bowel stimulant or irritant. This type of laxative acts primarily on the mucosa of the intestines and stimulates the nerve plexus to influence water and nutrient absorption as well as reabsorption. This alteration will then lead to the stimulation of peristaltic activity of the bowel. Thus, digestive tract movement is increased and stool elimination is induced. However, this may not be safe under certain circumstances. For this reason, stimulant laxatives must be used cautiously and employed for a short period of time only. As a result, Senna can also be employed as one of the weight loss herbal agents. Moreover, the leaf of Senna plant consists of essential oils which can potentially destroy harmful microorganisms that can cause skin irritations such as rashes, blisters and acne. In the traditional medicine, Senna leaves are prepared in the form of paste which is then applied on skin to treat ringworms and other skin infections. In addition, another health benefit of Senna is its potent antioxidant property. According to chemical studies, Senna herb contains high amount of antioxidants. Antioxidants are important to the body because they help prevent diseases by way of eliminating harmful toxins from the body. One of these harmful chemicals is called free radicals. These kinds of substances occur naturally in the body as an end – product of biological reactions. Free radicals can cause interruption on cellular division by altering replication of DNA. Aside from that, it can also cause damage to healthy cells of the body, thus promoting illnesses and diseases. With the several health benefits of Senna, it must not be employed as a substitute to prescribed medications. This herb is available in supplements. You can purchase this product in many health and drug stores or even Online. However, it must not be abused. More importantly, medical consultation must be done first so that adverse effects and untoward drug interactions will be avoided. Use Senna herbal supplement as labeled or prescribed. Like any other laxative, do not use this in large amount and for a longer period of time. This may cause dependence in which you cannot have a bowel movement without the use of such supplement or laxative.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2463) What is The Herb Yellow Dock Root And How Does It Detox
Date:
April 20, 2011 03:02 PM
What is The Herb Yellow Dock Root Good for?Yellow dock root is a health tonic best known for its detox properties. It has enjoyed a long association with folk medicine since the ancient times, especially in the treatment of what were believed to be diseases of the blood. Today it is often linked to the removal of heavy metals and other toxins from ingested foods, and thus has been attributed with digestive and hepatoprotective properties. Rumex crispus is known by many names in the vernacular throughout the ages, but the most common is yellow dock, which to this day remains popular. It is a shrubby plant species native to Europe and parts of Asia. It is a flowering plant that grows up to 1 meter in height, with a circular arrangement of basal leaves similar to that of dandelion. It thrives well in the wild, preferring open spaces, even roadsides, rail beds, and car parks, as long as the soil has enough moisture. Its seeds are on its stems and quite exposed, making it easier to propagate. It is believed to be widespread in all continents, with the obvious exception of Antarctica, and considered an invasive weed in many countries. The part of the plant used in herbal preparations is, as its name suggests, its root. Yellow dock root are dried and made into tea. Supplements in the form of capsules and tablets contain extracts of the dried root. Its active ingredients are phytochemicals with laxative properties, such as anthraquinones. It contains chrysophanic acid, which has been studied for its positive effects on skin disorders. In addition, it is a good source of vitamin C and iron, the reason why it is good for the blood. Cleanses the Body of Toxins Yellow dock root is thought to bind with toxins found in food and promote its excretion through the feces. It is particularly good for the organs close to the digestive tract, such as the pancreas, the liver, and the gall bladder as it promotes the production of enzymes needed for the breakdown of foods and protects the liver from the harmful effects of hepatitis. Also, it is believed to cleanse the lymph nodes. As it contains high levels of iron, intake of yellow dock root has been tied to healthier red blood cells. Alleviates Skin Inflammation Chrysophanic acid occurs naturally in several plants, including yellow dock root. This organic compound has been observed to allay the symptoms of many medical conditions of the skin that are inflammatory in nature, such as contact dermatitis, atopic eczema, and acne rosacea. Folk medicine practitioners believe that eating or drinking yellow dock root reduces the severity of herpes outbreaks. Promotes Bowel Movement Yellow dock root is rich in anthraquinones, notably emodin. In medicinal niches, these compounds are valued for their purgative properties. In the old days, herbal preparations containing yellow dock were heavily utilized in the treatment of different digestive problems such as indigestion and diarrhea. It is particularly helpful for constipation as it stimulates the colon and promotes bowel movement.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2279) Can Herbs and Prunes Help with Constipation
Date:
March 30, 2011 02:41 PM
Herbs and Prunes as a natural laxativeHerbs and Prunes must be the best digestive formula out there. It contains a select combination of herbs whose laxative properties are tried and tested for decades, namely: senna leaf, Chinese rhubarb root, Chinese asparagus, beet leaf, buckthorn bark, cabbage leaf, cascara sagrada bark, celery leaf, cranberry fruit, Culver’s root, parsley leaf, spinach leaf, and prune fruit. In addition to their long-standing association with alternative medicine, medical research has pointed to their active ingredients that are purgative in nature. These herbs not only relieve digestive problems such as constipation and indigestion but also cleanse the gastrointestinal tract, effectively disposing of toxins. Induces Bowel Movement There are several factors that may give rise to constipation, but in most cases it results from withholding bowel movement far longer than what is considered normal. In general, a healthy individual is expected to discharge fecal matter from the bowels at least once a day although it may vary from person to person. The rectum sends messages to the brain every time the final phase of digestion is about to take place, and not responding to these messages leads to reversing the direction of the feces, which are temporarily stored in the colon. However, the colon is not able to reduce the pressure the feces produce for long periods of time, leading to constipation. The unique formulation of Herbs and Prunes relaxes the intestinal walls and softens the stools, making it much easier to evacuate the bowels. Alleviates Abdominal Pains The phytochemicals that are considered the active ingredients of Herbs and Prunes include anthraquinones, such as senna glycosides, sorbitol, and isatin, such as dihydrophenylisatin, among others. These organic compounds are reputed for their laxative properties that soothe the muscles tissues within the intestinal walls and influence the releases of chemicals that sensitive the digestive tract to pain. Irregular bowel movement causes what we refer to as stomach pains, and more often than not the foods that we eat influences regularity. A balanced diet is named so because it promotes digestion as well as gives us the nutrients our body needs in right amounts. Herbs and Prunes works on the principle of supplying our body with all-natural, plant-based dietary fiber and phytochemicals that restores normal digestion. Detoxifies the Digestive Tract Herbs and Prunes comprises a significant fraction of both soluble and insoluble fiber that are guaranteed to wash away toxins when ingested with ample amounts of liquids. As diet significantly influences human health, it is not surprising that the digestive system may be rendered susceptible to unhealthy foods. The alimentary canal is our first line of defense against toxins that the foods we eat produce. Plant-based foods that contain fiber remove by-products of digestion that otherwise accumulate in the bowels. In conjunction with phytochemicals, fiber is known to reach parts of the alimentary canal that play host to harmful microorganisms, the reason why plant-derived medications are often the cure to many diseases of the digestive system.
Herbs and PrunesIt is always recommended to keep a herbs and prunes formula on hand when irregularity hits. Grab yourself a bottle today!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2263) Does Aloe Vera Juice Help with Digestive Problems?
Date:
March 28, 2011 02:01 PM
Aloe vera and your ColonAloe vera juice is one of the oldest herbal remedy for digestive problems that up to now remains in common use. It is extracted from the succulent plant aloe vera, which is known for its medicinal properties all over the world. Cultivation of this medicinal aloe predates written history, and its place of origin has eluded scholars for centuries. The fact that it is widely distributed across the globe today makes it a ready source of medicine in treatment of common digestive ailments. Also, large-scale production has contributed to its growing popularity worldwide. You may have heard of aloe vera juice as a health tonic. Folk medicine practices in just every continent highly value this medicinal aloe for its cleansing properties, but the first recorded use for illnesses of the gastrointestinal tract is in an Egyptian medical papyrus. In Greek and Roman antiquity aloe vera extracts in the form of juice were prescribed by physicians who practiced humorism to patients afflicted with constipation, diarrhea, indigestion, and stomach cramps. Both De Materia Medica by Greek botanist and pharmacologist Pedanius Dioscorides and Naturalis Historia by the Roman natural philosopher Gaius Plinius Secundus made mentions of its medicinal powers known to cleanse not only the alimentary canal but also the blood. Heals Ulcerations of the Gastrointestinal Tract It is common knowledge that aloe vera promotes the healing of wounds and other skin lesions. Aloe vera juice works on the same principle when ingested. This medicinal plant contains phytochemicals that increases the rate of healing of skin lesions and damaged epithelial cells of the gastrointestinal tract. There is a growing body of literature devoted to the effects of this medicinal aloe on inflammatory intermediaries present in the processes that are implicated in lesion of body surfaces, including the inner walls of the alimentary canal. Inhibits Growth of Harmful Strains of Bacteria Aloe vera juice has long been postulated to have antibacterial properties, and scientific evidence in support of this claim has surfaced in the past few years. One of the reasons why aloe vera speeds up the recovery of wounds is the fact that it is both bacteriostatic and bactericidal in nature, which means it inhibits the growth of bacteria and actively eliminates them at the same time. In addition, aloe vera contains polysaccharides that benefit probiotics, or friendly bacteria. By raising the number of helpful strains of bacteria such as lactobacillus, populations of harmful bacteria are curbed. Induces Peristaltic Movement of the Intestines There is strong scientific evidence that aloe vera juice is particularly beneficial for individuals afflicted with constipation. For one, anthroquinone glycosides found in aloe vera have been noted to accelerate defecation by adding bulk to the impacted feces and attracting water to soften the stool. Furthermore, aloe vera stimulates the muscle cells within the intestinal walls, which consequently produce contractions. The resulting peristaltic movement moves the ball of food, leading to the evacuation of the bowels. Aloe vera is an excellent remedy to take daily to maintain good intestinal health as well as skin health. Take your aloe daily!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2260) What are the Health Benefits of Vitamin K?
Date:
February 19, 2011 11:42 AM
6 Ways Vitamin K Can Boost Your HealthVitamin K is belongs to the group of vitamins that are soluble in fat. There are a lot of chemical compounds that display the activities of this essential nutrient inside the human body, but the best known form of this vitamin is phylloquinone, a naturally occurring substance in green leafy vegetables. Many different synthetic forms have also been proven to exhibit the same health benefits. Helps against Blood Loss Vitamin K was named so largely owing to the fact that it is directly involved in the coagulation of blood, which was the first of its benefits to be discovered. K stands for the first letter of its German name, Koagulationsvitamin. The process by which our body controls blood loss during bleeding, both external and internal, is called coagulation, which describes the ability of the blood to thicken and form a clot. Coagulation is central to the health of blood vessels as it stops bleeding and starts the healing process. Promotes Vascular Health Phylloquinone and other forms of Vitamin K have long been used as a treatment for cardiovascular diseases. One form of calcification outside the bones occurs in the arterial linings, which wears down the elastic properties of vascular tissues. Arterial calcification in itself is a very serious medical condition and usually takes place in end-stage cardiovascular diseases. However, the absence of vitamin K in the body also brings on this disease. Facilitates Calcium Absorption There is strong evidence that vitamin K helps build strong bones, and is in fact utilized as treatment for osteoporosis. Vitamin K modulates the production of osteocalcin, which induces bone formation and reduces bone resorption by attracting calcium minerals inside the body. Premature calcification of bones negatively affects bone density, but the presence of vitamin K has been observed to avoid this. Regulates Blood Sugar The bone-building protein osteocalcin also acts as a hormone that triggers the beta cells in the pancreas to release more insulin, which instruct cells in different tissues of the body to absorb glucose from the blood. Glucose is either converted into ATP, the primary source of energy that power cellular functions, or stored as glycogen inside the cells. Either way maintains healthy blood sugar. Breaks down Body Fats Osteocalcin is also involved in the burning of fats in adipose tissues, including the unwanted flab on the belly. By stimulating these fatty tissues to release a hormone called adiponectin, body fats are broken down into smaller particles and in the process release energy. In fact, the abundance of adiponectin in the bloodstream has been closely tied to low percentage of body fats in adults. Scavenges Free Radicals Vitamin K helps clear the body of ravaging free radicals that damage everything at the cellular level. It is particularly associated with protecting the nerve cells from premature death due to oxidative stress caused by free radicals, the reason why it is used in studies concerning Alzheimer’s disease and cancer. With all its health benefits, it is prudent to ensure consumption of Vitamin K.
Do you get enough Vitamin K Daily?
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2240) Cascara sagrada can help with constipation
Date:
August 25, 2010 02:18 PM
Cascara sagrada and ConstipationCascara Sagrada was introduced to the Spanish explorers by Native Americans when they complained of problems with constipation. The Spanish then gave this herb its name, cascara sagrada, which means sacred bark and used it as a natural laxative. The Spanish explorers brought the herb back with them to Spain when they returned. In 1877, this herb was admitted to the U.S. Pharmacopoeia and is still included as an official medicine to this day. Cascara sagrada is believed to be one of the best herbs for treatment of chronic constipation. This is because it enhances the peristaltic action that takes place in the intestines and increases the secretions of the stomach, liver, and pancreas. This herb is also helpful in relieving hemorrhoids because of its nonirritating nature and softening action on the stool. Cascara sagrada is found in many over-the-counter preparations that are used for the intention of relieving constipation. This is because it acts on the large intestine to increase the muscular activity of the colon. The anthraquinones that are found in cascara sagrada are believed to encourage intestinal contraction. This herb is used to restore natural bowel movement without griping and to restore tone to the bowel.
Additionally, an element in cascara sagrada is known as quinine emodin. This element is being studied for its usefulness in treating lymphocytic leukemia and Walker carcinosarcoma tumor Cascara sagrada can be used often, as it is not considered to be addictive. Preparations should be made from bark that has been aged for a least a year before use. This must be done because fresh bark is poisonous and can cause nausea and extreme griping on the intestinal system. Cascara sagrada can be found in various forms including capsules, liquid extracts, and dried bark. Although it tastes bitter, the dried bark can be made into a tea. A typical dosage of cascara is a 300 mg capsule which is taken in the early evening to stimulate a bowel movement in the morning. The laxative effect usually occurs 6 to 12 hours after cascara is taken. Products containing cascara sagrada should not be used for more than eight or ten days. Those women who are pregnant and nursing should avoid this herb, as well as people with intestinal blockage, undiagnosed stomach pain, or symptoms that may indicate appendicitis. People with diarrhea, inflammatory bowel disease, or intestinal ulcers should not take this herb. Additionally, children younger than twelve with constipation should not be treated with cascara sagrada. The bark of cascara sagrada should be used to provide alterative, antineoplastic, antispasmodic, hepatic, lithotriptic, and purgative properties. The primary nutrients found in this herb are calcium, chlorine, iron, magnesium, manganese, niacin, phosphorus, potassium, selenium, silicon, sodium, and vitamins A, B-complex, and C. Primarily, cascara sagrada is beneficial in dealing with colon problems, constipation, gallbladder problems, gallstones, gas, gastric disorders, hemorrhoids, intestinal problems, liver disorders, and worms. Additionally, this herb is extremely helpful in treating colitis, coughs, croup, dyspepsia, gout, indigestion, insomnia, jaundice, excessive mucus, pituitary problems, and spleen ailments. For more information on the many beneficial effects provided by cascara sagrada, please contact a representative from your local health food store. Always choose name brands of this wonderful herbal laxative to ensure quality and purity and gentleness of its properties on the intestinal tract.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2180) Pau d'arco Bark
Date:
November 10, 2009 11:23 AM
Pau d'arco is found growing in a tree high in the Andes and can weather the worst storms because of its hard wood and deep roots. This herb is found in the inner bark of the red lapacho tree. Most of the trees surrounding this tree eventually become covered with spores, which lead to fungus, and this eventually kills the trees. However, the red lapacho seems to be able to resist the spores. This may be a contributor in pau d'arco's ability to heal the body and resist disease.
There seems to be some evidence of antitumor properties in pau d'arco. Many individuals have taken this herb when they are undergoing radiation and chemotherapy. Pau d'arco helps to strengthen the body and help prevent the side effects that are associated with cancer treatment. Additionally, this herb seems to be a powerful alterative and blood builder. It has the ability to increase the hemoglobin and red corpuscles that are found in the blood. It gives the body a greater vitality by increasing its resistance to disease. Pau d'arco seems to be responsible for giving the body energy and strength to defend itself and resist disease. The herb is also believed to help inhibit the growth of tumors and increase the growth of normal tissue. Furthermore, pau d'arco herb is used to aid in the assimilation of nutrients and the elimination of waste matter. Studies have found that a component of pau d'arco, quinine lapachol, has antimicrobial and antiviral properties. The herb also seems to have an antitumor effect without any toxic side effects. Additional components include beta-lapachone, hydroxyl-napthoquinone, alpha-lapachone, and xyloidone. These are effective against numerous viruses, bacteria, and fungi, including herpes, influenza, poliovirus, and many others. A researcher at the National University of Tucuman in Argentina, Dr. Theodoro Meyer, discovered the substance xyloidin. This substance is able to kill viruses. Xyloidin is also beneficial in inhibiting the causative agent of dysentery, tuberculosis, and anthrax. Pau'd arco is available at your local or internet health food store at discount prices. Look for name brands like Solaray, Source Naturals, and Natures Plus to ensure quality and purity of the product you purchase.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2111) Senna Leaf
Date:
August 06, 2009 12:58 PM
The American senna has been used widely for its mild purgative abilities. Native Americans used this as a drink to reduce fevers, for sore throat, and as a laxative. The herb was official in the U.S. Pharmacopoeia from 1820 to 1882. Senna was used in Chinese medicine. This herb, along with other laxatives, has been used since prehistoric times in order to treat colonic and menstrual obstructions. Senna can be found along the Nile River. The herb was used in Arab medicine as an effective and safe laxative. Nicholas Culpeper, the seventeenth-century herbalist, claimed that senna was able to clean the stomach and purge melancholy and phlegm from the head, brain, lungs, heart, liver, and spleen. The senna plant held a major role in herbalism and folk medicine for millennia. The herb was and still is a significant item of trans-national trade by the Ababdeh people. It is grown both commercially and traditionally along the middle Nile. However, more generally, it is found in many regions around the northwestern Indian Ocean. Senna is similar to aloe and rhubarb, as it has similar active ingredients such as anthraquinone and their glucosides. This herb is considered to be a useful laxative. It is responsible for intestinal parasitic movements. The herb has a strong effect on the entire intestinal tract, especially the colon. A lot of people believe that a clean colon can prevent autointoxication and may be an underlying cause of many diseases. Usually, senna is combined with other herbs, such as ginger or fennel, in order to prevent intestinal cramping and get better results. The herb should not be used if there is inflammation of the stomach. This is because it may aggravate the problem. Senna helps to tone and restore the digestive system through cleansing. The herb has been used throughout history and today, it is still used throughout the world. Senna acts on the lower bowel. It increases the peristaltic movements of the colon. Most often, the plants are prepared as an infusion. The long-standing use of senna is reflected by its presence in many herbal remedies and tonics. Today, senna is still used as the primary ingredient in certain commercial stimulant laxatives. However, it is also the primary ingredient found in dieter’s teas. However, the combination of acting as a stimulant, which reduces a dieter’s appetite, and the laxative properties that cause food to move through the system before many calories can be absorbed is a combination that can lead to rapid and even dangerous weight loss. Senna is a powerful laxative. The anthroquinon glycosides that are found in senna are believed to be responsible for the stimulatory effect it provides on the colon. Laxative should not be used for extended periods of time or dependency may occur. The leaves and pods of the senna plant are responsible for providing anthelmintic and mild purgative properties. The primary nutrients found in this herb are calcium, iron, magnesium, manganese, potassium, selenium, silicon, sodium, vitamins A, B-complex, and C, and zinc. Primarily, senna is extremely beneficial in treating constipation, jaundice, and worms. Additionally, this herb is very helpful in dealing with acne, excessive bile, breath odor, colic, gallstones, gout, menstrual symptoms, obesity, rheumatism, and skin disease.
In order to obtain the best results when supplementing with this, or any herb, it is important to consult your health care provider before beginning any regimen while on prescription medications. For more information on the many beneficial effects provided by senna, please feel free to consult a representative from your local health food store with questions.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2048) Gymnema Sylvestre
Date:
November 12, 2008 09:51 AM
Gymnema sylvestre is found naturally in central and southern India, where it has been used in traditional Indian medicine for almost two thousand years. It is known as 'gurmar' in ancient Indian texts, a word meaning 'sugar destroyer', which gives an indication of its uses in medicine. It is used to reduce the absorption of glucose into the body, and also reduce the sweetness of foods, both of which are desirable for those wishing to lose weight and to reduce the level of sugar in their blood. It was used for this purpose in Ayurvedic medicine, subjects being given the leaves to chew. As with many other ancient Ayurvedic remedies, this use of gymnema sylvestre has passed into modern times, and has sound scientific basis. First, however a bit more about the plant itself. It is found predominantly in the Western Ghats, and also to the west of the mountains, around coastal Goa. It is a vinous plant that climbs on other bushes and trees, known in Sanskrit as Meshasringa, or ram's horn after the shape of the leaves from which the supplement is extracted. For what it's worth, the official name seems a mix of Greek and Latin (gymnos(Gr) - naked and Silva (L)- forest) for naked forest. That, however, is irrelevant to its uses, so let's have a look at the science involved and the active ingredients in the plant. The main constituents are terpenoid saponins known as gymnemic acids, so one can assume that they were first found in this plant. They are glycosides, including hodulcine and ziziphin, which act as sweetness inhibitors so that there is no sweet taste in anything that is sweetened by sucrose. There are over 20 types of gymnemic acid in the leaves, of which the strongest, Gymnemic Acid 1, can suppress the sweetness even of artificial sweeteners such as aspartame. These are not irreversible effects, and last only about 10 minutes, after which normal sweetness is detectable by your tongue. During the active period, however, a solution of normal sugar will taste like ordinary unsweetened water. However, is this just a matter of taste, or does it affect the sugar itself? Studies have shown that animals fed the leaves of Gymnema sylvestre develop hypoglycemia, probably because it stimulates the pancreas to generate insulin that reduces the level of sugar in the blood. Further studies have shown the presence in the leaves of a number of types of acylated derivatives of deacylgymnemic acid. There are well over a dozen types of saponins known to be contained within the leaves. Other chemicals found include anthraquinones, flavanoids, chlorophylls, querticol, phytin, a number of glycosides and anthraquinones. The bush also contains alkaloids, although these are constituents in most plants used in ancient remedies. This is by no means all of the chemicals discovered, and many of the minor benefits of using it could be due to the minor constituents of this amazing little leaf. A study of the above constituents will reveal a few antioxidants, and it is no surprise that the extract from Gymnema sylvestre also possesses anti-inflammatory properties. Gymnemic acid is believed to have a similar chemical structure to saccharose, and the plant extracts can be used not only to reduce a craving for sugar, but also to treat digestive problems and high cholesterol levels. So what scientific evidence is there other than the obvious effects reported by those that use it? A study in the UK in 2005 found that an aqueous extract of Gymnema sylvestre caused the secretion of calcium and insulin from mouse and human cells to be increased at a specific concentration without affecting the cellular function. This means that the supplement can be used to stimulate the secretion of insulin with people with Type 2 diabetes without otherwise affecting health. Its usefulness to diabetics is obvious, but there are other health benefits to those that are not diabetic. Anything that modulates a sweet tooth must be of use to those seeking to lose weight, particularly if they feel the need for sweet foods. In fact Gymnema tends to reduce food cravings for carbohydrates and sweets, and can be used by those seeking a natural means of curbing their appetite for sweet and sugary foods. Because excess weight can lead to diabetes, Although there have been many discussions about the biochemical mechanism of the gymnemic acids in this effect on taste, recent evidence suggests that the phytochemicals act on both your taste buds and on those parts of the intestine responsible for absorbing nutrients from digested foods. Not only that, but studies have also indicated that Gymnema sylvestre removes the bitterness of acerbic chemicals such as quinine in the same way that it removes the sweetness form cakes and candies, and if you drank tonic water it would taste just like water. On the other hand, if you ate an orange, you would taste the acidity but not the sweetness. The way to use this remarkable supplement is to follow the instructions, and within about a week you will be able to control your appetite much better, and any cravings for carbohydrates you previously had will be much reduced. After a month or so, you will notice an accelerated rate of weight loss if you had been overweight, and diabetics will find a significant reduction on blood sugar between insulin shots.
Gymnema sylvestre can take care of any sugar or carbohydrate cravings, and is of significant use to the overweight, obese or to diabetics, and the mechanism by which it works has now been all but understood, although there are still some biochemical secrets that this amazing plant has yet to reveal. This amazing herb can be found at your local or internet vitamin store.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1935) Damiana Leaves
Date:
May 22, 2008 11:45 AM
Damiana can be used by both men and women. It is known to have restorative effects on reproductive organs in both sexes. Uses: For men, Damiana is known to raise levels of testosterone. It is also helpful in treating premature ejaculation and impotence. For women, it helps to induce delayed menstrual periods and ease the symptoms of painful menstruation. It also treats the headaches women sometimes get due to menstruation. This herb has been widely advertised and used in Mexico as an aphrodisiac. The ancient Mayans used it as a sexual stimulant and people in Central America still use it in this way today. This use is controversial due to lack of scientific evidence to support the claim. One study found some of the plant's compounds to be similar to those found in progesterone. More than 150 herbs have been tested for their ability to bind with the progesterone and estrogen receptors found in breast cancer cells. Damiana was one of the highest progesterone-binding herbs tested. The herbal properties of Damiana have a life enhancing and stimulating effect on the body and mind. The herb works well on nervous exhaustion and to restore the body after periods of high stress. Other Uses: Damiana's stimulating action is considered very valuable to people who suffer from mild depression. Herbalists will typically recommend remedies that contain this herb. Damiana is very strong and aromatic, and has a slightly bitter taste. It can be found in different forms such as capsule, liquid extract and tea. Its leaves are used as a substitute for tea leaves in some countries. In other countries, it is used as flavoring in a variety of liqueurs. Damiana acts as an antiseptic and tonic for the body. It is also a restorative agent for nervous system functions. Damiana is used for other conditions as well, although no scientific proof of its effectiveness exists. These conditions include: * Asthma * Anxiety * Depression * Headache * Menstrual disorders Damiana has been known to cause mild indigestion for some users. It also contains a compound called arbutin, which, in the urinary tract, converts into the chemical hydroquinone. Larger amounts can cause serious side effects such as: * Convulsions * Tinnitus (ringing in the ears) * Nausea * Vomiting * Possible collapse and death A maximum safe dosage of Damiana has not yet been determined. Also, the safety of using this herb has not been established in children or pregnant and nursing women. People with liver or kidney disease should use extra caution because their ability to safely use this herb is unknown as well. In people using higher doses of Damiana, it is believed that they experience a mild euphoric sensation. In some cases, consumption of Damiana leaves has been known to act as a mild laxative. The more leaves consumed, the more prominent the laxative effect. Damiana is native to parts of southern California and the Gulf of Mexico. It can also be found growing wild in some areas of the northern Caribbean Islands and Namibia. It is widely cultivated in these areas. Its preferred habitat has a hot and humid climate. It flowers in the summer and this is when the leaves are harvested. The leaves of the Damiana plant are the only part used for cultivation. The herb can be taken in the form of a tea. Some people even smoke it like tobacco. The herb will bring about a relaxed state of mind for the user. It is said to induce a subtle high if smoked.
Damiana possesses many properties that are useful to both men and women. Research continues in an attempt to either prove or disprove claims of its benefits to humans.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1796) Ubiquinol
Date:
April 16, 2008 01:10 PM
Coenzyme Q10 is an important cofactor that is found in nearly every cell of the body. Coenzyme Q10 is naturally produced by the body as well as attained through the foods we eat or in supplement form. With out it, every cell in our body could not produce energy to function and we would die. Coenzyme Q10 has the capability to regenerate antioxidants, protecting cells and DNA from oxidative stress which naturally occurs in the body every day. Some may say that coenzyme Q10 exists in only one form, but in fact this substance exists in at least three forms in the body naturally. These three forms are CoQ ubiquinone, CoQH ubisemiquinone and COQH2 ubiquinol all of which are metabolically active forms of coenzyme Q10. Ubiquinone has been commercially available for more than 30 years normally consumed orally, but recently stable forms of Ubiquinol have been made available for consumption which is of great interest by many researchers. The former ubiquinone when ingested had to be reduced by an enzymatically driven conversion from ubiquinone to Ubiquinol in the digestive tract. This conversion is done by the transfer of electrons effectively reducing the coenzyme Q10 to a more usable form Ubiquinol. Once Ubiquinol is produced the body can more easily manufacture ATP which is directly used by cells for cellular energy. In young individuals, 90 percent of coenzyme Q10 found in the blood is in the Ubiquinol form. This being the case, the old form (ubiquinone) was less absorbable then the newer Ubiquinol that can go right to work in the body. Ubiquinol is considered the strongest lipid soluble antioxidant that is biosynthesized, providing an active defense against oxidative stress that damages, cells, proteins, lipids, and DNA. Some scientists believe that cellular damage from free radicals cause our bodies to age. The older we get the less our bodies produce coenzyme Q10 which in its self is an antioxidant and restores other antioxidants in the body to fight the war against free radicals. Eating foods rich in antioxidants and or supplementing with antioxidants may slow the aging process. With age, disease, and some prescription medications, the old form of coenzyme Q10 can not easily follow the process of absorption in the intestinal tract where it is reduced and shuttled through the lymphatic system into the circulatory system (blood). This is why Ubiquinol was so highly sot after. Ubiquinol is already reduced, the preferred form coenzyme Q10 the body wants to circulate and retain. When one ages, energy levels always drop and one tends to slow down and feel tired sooner in the day, this may be because of a drop in coenzyme Q10 in the blood. Many recent studies suggest that the plasma Ubiquinol ratio is reduced in response to cardiovascular disease, neurodegenerative disease, cancer, fatigue and especially in type-2 diabetes. Supplementing with Ubiquinol can help restore plasma levels and boost ones energy levels and possibly slow diseases. To sum it up, if you are over 45, suffering from a degenerative disease or cancer, feel tired and run down, or taking prescription medications, conventional coenzyme Q10 is not what you want to take to elevate plasma levels. Ubiquinol is needed because the body can not adequately produce the most abundant form of coenzyme Q10 in he blood (Ubiquinol). So for those who want to maintain health and wellness, look for Ubiquinol in their local health food store.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1757) Bilberry Extract Is A Powerful Antioxidant That Strengthens Veins
Date:
April 12, 2008 11:06 AM
Bilberry extract is taken from the Vaccinium myrtillus, or bilberry, a small blue berry that has been used traditionally for the treatment of conditions now known to be due to inflammation and the action of free radicals on the body. Among these is atherosclerosis, or hardening of the arteries, caused by the free radical oxidation of the low density lipids that carry cholesterol around the bloodstream, and that cause deposition of fatty plaques on the arterial walls and eventually constricts them to a stage that can cause heart failure or a stroke, depending on whether the arteries are close to the heart or in the brain. However, additional to treating this condition, bilberry has also traditionally been used for the treatment of varicose veins and also for certain eye conditions. In fact it was during the Second World war that the Royal Air Force in Britain received reports from pilots that their night vision improved after eating bilberries. Not only their vision, but the restoration of night vision after exposure to glare. This was extremely important to war-time pilots who had to be able to rapidly adapt their vision to fly their plane after exposure to searchlights and explosive detonations. That is the reason for anything that appeared to promote this essential adaptation to be reported. The pharmacology of these effects have been found to be due to the anthocyanosides in which bilberries are particularly rich. Anthocyanosides consist of an anthocyanaidin backbone, to which one of either arabinose, galactose or glucose can be bound. Since bilberry contains five of these anthocyanadins, then there are fifteen different anthocyanosides in the fruit concentrate. The area of the retina that appears to control night vision, and the transition from day to night sight, is called the epithelium which is connected with purple vision. Anthocyanosides seem to have an affinity for this part of the retina, and in so doing plays an important part in this type of vision, specifically night vision although it is also beneficial in improving day vision. Although bilberry also contains vitamins A and C, hydroquinone and tannins, it is the anthocyanosides that provide it with its unique antioxidant properties, and also its effect upon collagen fibers. It can cross-link collagen fibers to help overcome weaknesses in the connective tissues such as cartilage, tendons and the walls of blood vessels. Its effect as an antioxidant is to prevent the cleavage of collagen by the cyzymes that are secreted by leukocytes generated by the immune system. By preventing histamine release, and release of prostaglandins and other proteins and cells mobilized during the immune inflammatory response to the detection of foreign invasion into human tissue, anthocyanosides can help to reduce inflammation and to protect against other extreme reactions of the immune system that can harm the organism it evolved to protect. The most powerful property of anthocyanosides are their antioxidant properties: perhaps even its only property once all of the conditions it helps to protect against are fully understood. An antioxidant combines with free radicals and destroys them. Free radicals are particularly vile chemical entities that require an electron to make them stable, and they take this electron from the nearest source. This can result in oxidation and destruction of many bodily tissues leading to premature aging, atherosclerosis, eye damage and many other problems that result from the destruction of body cells and tissue. The various constituents that make up bilberry act in concert to scavenge the free radicals and increase the supply of oxygen to the eye. The benefits of this are in helping to prevent cataracts and glaucoma, the latter due to the effect of the anthocyanoside cross-linking effect on the structure of the collagen in the eye. It can also help in cases of macular degeneration that affects the central area of the retina which might be due to the same property of there glucoside. Moving away from the eyes and back to the vascular system, the collagen cross-linking properties of the flavonoids, which is what anthocyanosides basically are, can help to repair damaged vein tissue by strengthening the vein walls themselves, and also by providing support for the cell membranes, or outer layers of the cells. This in turn builds up more strength in the vein tissue below the outside walls and contributes to an overall reduction in the weakness of the vein. This in turn enables it better to withstand the internal pressure put upon it by the failure of the valve that created the problem. In this way bilberries can be used to help repair the damage done by varicose veins and improve the function of the vein in returning blood to the heart from the extremities of the legs and also to help reduce the pain and swelling of varicose veins. In addition to these beneficial effects on the vascular system and the eyes, bilberry can also help to decrease the permeability of the blood-brain barrier to pollutants, drugs and other undesirable chemicals by improving the resistance of the capillaries in the brain to the transfer of such substances through their walls. It does so by preventing the collagen of the capillaries in the brain being degraded either by enzymes or other agents, Also, by helping to strengthen that collagen structure so that it becomes more impermeable to the larger molecules that form the pollutants. A lesser known constituent of bilberry is myrtillin, an anthocyanoside monoglucoside that is also available in all green plants, that possesses anti-glycemic properties. What this means is that it can reduce hyperglycemia and glycosurea, and so reduce blood sugar without reducing the blood sugar level to dangerously low levels. In other words it is an ideal insulin substitute. Native Americans used green plants for teas for centuries and were free from diabetes until the came into contact with Europeans and adopted their dietary habits. Although the case has to be proved, it appears highly likely that it was the myrtillin that kept them free from a condition that affects so many other races. Irrespective of that, however, it is for its powerful antioxidant effect that bilberry finds its best use, and also its effects on varicose veins. However, all of the above health benefits that bilberry provides, can likely be laid at the door of the combined antioxidant effect of its vitamin C content and the anthocyanosides – including the glucoside myrtillin.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1753) Ubiquinol Reduced CoQ10
Date:
April 07, 2008 01:05 PM
Ubiquinol, which is the reduced from of Coenzyme Q10 (CoQ10), has been recently added to the supplement offerings of many companies and has generated a lot of confusion along with its excitement. As a supplement, ubiquinol is somewhat new, but as a critical part of human metabolism, our knowledge of ubiquinol goes back to the discovery of CoQ10. Although CoQ10 is often thought of as a “static” nutrient in the context of nutrition, it actually interchanges between two useful states: the oxidized ubiquinone, and the reduced ubiquinol. Coenzyme Q10 is a member of a family of important biological compounds which are referred to as ubiquinones. It is a lipophilic, water-insoluble substance, which takes part in a large array of biochemical oxidation and reduction reactions. It was first identified in 1957 as an essential component of the energy production system in cells. CoQ10 and other members of the ubiquinone family have, since then, been identified as critical metabolic compounds in a range of aerobic organisms. Because of its crucial role in metabolism, humans have the ability to make their own CoQ10, although small amounts can be obtained through diet and as supplements. In humans, CoQ10 is found in each cell in the body, but is particularly abundant in tissues which have large energy requirements such as the heart, liver, kidneys, and skeletal muscles. Smaller amounts can be found in the brain, lungs, and intestines. There are also substantial amounts that can be found in circulation, which are most often associated with lipoprotein particles. In total, CoQ10 in a normal adult has been estimated to be between 0.5 and 1.5 grams. Inside cells, about half of the CoQ10 is found within the mitochondria, where the final steps of CoQ10 production occur. CoQ10 which is not located in areas of the cell and are not charge with producing cellular energy can amount to about 50-60 percent of the total CoQ10 pool. CoQ10 can be found throughout cell membranes and in other cellular structures such as the nucleus, cytoplasm, and endoplasmic reticulum. Some experimentation has also concluded that, while the final steps of CoQ10 production occur in the mitochondria, it can be exported to other sub-cellular locations. While participating in various oxidation and reduction reactions, CoQ10 is cycled between two stable states: a fully oxidized form referred to as ubiquinone, and a fully reduced form called ubiquinol. CoQ10 cycles through these oxidated/reduced forms in order to achieve its metabolic goals. The cycle of CoQ10 is simple. Ubiquinone picks up electrons and then becomes ubiquinol. Ubiquinol then release its electrons and becomes ubiquinone again. Therefore, it would seem that CoQ10 has a very simple function of moving electrons, as the transfer of electrons is a fundamental step in the production of energy, the regeneration of antioxidants in cell membranes, and the construction of other important biological molecules. Each cell that is in the body needs a source of energy in order to survive. Therefore, sugars, fats, and amino acids are broken down in order to make energy. In the mitochondria, CoQ10 is abundant, as it carries electrons to aid in the chemical reactions that burn cellular fuel and produce chemical energy to form ATP. Since substantial amounts of ATP are needed to power our cells, the importance of CoQ10 in human metabolism is easily understood. Both forms of CoQ10 are needed to transfer electrons between energy-producing reactions. Outside of the mitochondria, CoQ10 performs a slightly different role as a membrane and antioxidant. About half of the human body’s total CoQ10 pool may be functioning in this capacity. CoQ10 is one of the major antioxidant elements of the LDL particles and is also one of the first to be depleted when LDL is subjected to oxidation. A discussion of CoQ10 would not be complete without mentioning its documented health benefits. Supplemental CoQ10 has been the subject of a lot of studies over the last half century, especially in applications for cardiovascular health. Many studies have shown benefits of CoQ10 in patients who are diagnosed with chronic heart failure, exercise-induced angina, hypertension, or those who have recently experienced infarction. There is also early evidence showing that CoQ10 may protect the heart from damage during chemotherapy, bypass surgery, or in diabetes. Aside from its cardiovascular uses, CoQ10 has been studied for its benefits in other conditions involving dysfunctions in cellular energetics, neurological degeneration, or oxidative stress damage. Although the clinical evidence for the potential benefit of CoQ10 in many of these applications shows promise, the variability in study outcomes proves it necessary to further research these areas for a more definite answer. As we have previously seen, CoQ10 functions by cycling between two stable forms, ubiquinol and ubiquinone. This cycle results in the generation of cellular energy and the protection of membranes and lipids from oxidation. Dietary or supplemental CoQ10 also takes part in this cycle. Supplemental ubiquinol may have a distinct advantage over ubiquinone in its facility of absorption. Like many fats and lipophilic nutrients, CoQ10 is usually taken up by the intestinal electrolytes, packaged into lipid particles, and then released into the lymphatic system. From there, these particles are transferred into circulation where they are free to be transported throughout the body as needed. The absorption of dietary CoQ10 is actually quite poor since it has limited solubility in lipids and depends on other contents of the gut. Some studies have measured that absorption is as low as 2-3 percent of the total dosage. One of the most thrilling consequences of the development of a stabilized dosage form of ubiquinol is its ability to be absorbed more efficiently than ubiquinone. There is evidence that CoQ10 must be reduced in intestinal enterocytes before the release into the lymphatic system. This, paired with absorption/reduction, may be a rate-limiting step of CoQ10 assimilation. Dietary ubiquinol avoids this reduction reaction, and is directly available for absorption, which explains why ubiquinol-based CoQ10 supplements exhibit enhanced bioavailability over ubiquinone supplements. Preliminary studies in humans have shown that absorption of ubiquinol is at least double the absorption of ubiquinone. Comparisons of blood levels between trials also estimate the improvement in absorption to be significantly higher. Future studies are necessary to more accurately determine ubiquinol’s enhanced absorption, and what effect the patient age or medical condition may have on these results.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1743) Ideal Users For Vitamin K2
Date:
April 02, 2008 03:31 PM
Ideal Users: NOW® Vitamin K2 is ideal for healthy adults looking to support strong, healthy bones, as well as sound cardiovascular health. Complementary Products: Consider taking this product in combination with NOW® Vitamin D and Calcium and/or Calcium & Magnesium supplements. Recommended Use: As a dietary supplement, suggested use is 1 Vcap®, to be taken daily with a meal. Supporting Science Bolton-Smith C, McMurdo ME, Paterson CR, et al. A two-year randomized controlled trial of vitamin K(1) (phylloquinone) and vitamin D(3) plus calcium on the bone health of older women. J Bone Miner Res. 2007 Jan 23. Knapen MH, Schurgers LJ, Vermeer C. Vitamin K(2) supplementation improves hip bone geometry and bone strength indices in postmenopausal women. Osteoporos Int. 2007 Feb 8. Additional information: It is important for users to consult their health practitioner before consumption, especially if they are currently taking anti-coagulant drugs (i.e. warfarin, coumadin, heparin), or if you are pregnant/lactating. To avoid the risk of excessive blood thinning, do not take more than the recommended dose.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1737) Vitamin K2 - Description by Now Foods
Date:
April 02, 2008 03:29 PM
Product Description: NOW ® Vitamin K-2 contains 100 mcg of vitamin K-2 (as Menaquinone) per Vcap®. Vitamin K2 is the most biologically active form of vitamin K. Additionally, it is also the most beneficial for bone integrity, as well as for the support of arterial health.* To enhance its cardiovascular support properties, we’ve added 300 mg of Alfalfa, a plant that is well known for its rich stores of naturally-occurring vitamin K. NOW® Vitamin K-2 is vegetarian/vegan friendly, and free of many common allergens, including sugar, salt, yeast, wheat, gluten, soy, milk, egg, shellfish or preservatives.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1736) Seniors Need More Than a Multiple with Only 100 Percent of the RDA
Date:
January 21, 2008 03:14 PM
The aging process is a gradual one. That might seem obvious, and it is, but it is the fact that it is gradual that causes people not to notice the small but significant changes in their body that are taking place. Aging is more than just the oxidation of skin cells that cause them to wrinkle, but involves specific functional cell changes, such as their ability to multiply. As this slows down the immune system is affected, and we find it more difficult to recover from injury and disease. Oxidation becomes more prevalent and free radicals become more common as the natural antioxidants of our bodies become overwhelmed. We are less able to recover from the effects of environmental stress, such as UV radiation from the sun, pollution and the effects of heat. We find it increasingly difficult to deal with a lack of nutrition or toxins in our food from pesticides. In short, we become less capable of dealing with attack by invaders, but do not notice this gradual lack of immune response. Age also affects our joints from the vertebrae in the neck to the joints of our toes. The net result is a compression of the bones that causes a reduction in height. We also develop more body fat and less muscle tissue, which is a significant consideration in planning the nutritional needs of the elderly. However, of more critical importance when discussion the nutritional needs of our aging population is the possibility of malabsorption. Malabsorption is an inability of the digestive system to absorb nutrients from food, and occurs in people of any age although it tends to be more prevalent in seniors. It is predominantly due to a dysfunction of the liver, the pancreas or the small intestine that are the three major physical components of the human digestive system. The liver produces bile that is needed to process the fats in your food, and if the bile is not delivered to the small intestine, then malabsorption is possible. The same is true of the enzymes that are produced by the pancreas These enzymes are important components in the biochemistry that allow us to absorb nutrition from our food, and since most of this absorption occurs in the small intestine, this too is essential for proper absorption. When any of these three are reduced in efficiency, as they are with advancing years, then malabsorption will occur. When this occurs in seniors, however, it is essential that a multiple supplement with more than 100% of the RDA (Rcommended Daily Allowance) is used. This type of nutritional deficiency can be very serious at an age when so many normal biochemical processes are slowing down, and it is important that steps are taken to avoid the serious problems that can arise. The immediate symptoms of malabsorption are diarrhea and weight loss, although the more serious longer term effects are anemia due to a deficiency in folic acid and iron and a reduction in the blood’s ability to form clots due to a deficiency in vitamin K absorption. There are others, but not all problems associated with aging are actually due to malabsorption, or even with aging. Many of the problems associated with aging are now believed to be connected with the patient’s lifestyle and diet. Heart disease such as atherosclerosis is now known to begin earlier in life, as are many other conditions once believed to be associated with age. A loss of cognitive ability can be age related, but also due to cigarette smoking and excessive alcohol consumption. However, irrespective of all this, it is essential that the aged are provided with vitamin and mineral supplements offering more than 100% RDA. Calcium is of particular importance for older women who are particularly prone to osteoporosis due to malabsorption of calcium from their food. At least 1000mg daily should be taken, and extra magnesium and vitamins A and E will also be necessary since they are needed for the proper absorption of calcium. The extra does not infer that all of the supplement will be absorbed, but that enough should be to help reduce the possibility of bone density problems. The elderly are particularly prone to vitamin B deficiencies, particularly of vitamin B12, due to absorption problems and a good vitamin B complex supplement is needed. Chromium too can be seriously depleted in the aged, and this mineral is necessary to enhance the activity of insulin. It is also believed to play a part in the metabolism of carbohydrates, proteins and fats. There are no known consequences of an excess of chromium so a good supplement can be provided. It is believed that vitamin B and chromium together are required for cardiovascular and neurological health that are so important as we age. One important supplement for the elderly is Coenzyme Q10. Many older people are prescribed drugs such as statins for the treatment of high cholesterol levels. Statins work by depressing the biochemical synthesis of cholesterol by blocking the action of mevalonate, and this is known to interfere with the metabolism of Coenzyme Q10, otherwise known as ubiquinone. CoQ10 is essential in allowing the production of energy within the cell mitochondria by allowing electron transfer back and forth between NAD and NADH to allow the production of adenosine triphosphate (ATP). A supplement of this important enzyme is therefore essential in maintaining the energy levels of the aged who are being prescribed statins. Almost 20% of the elderly on prescription drugs are also taking herbal remedies and supplements, and there could be an interaction between them. Anybody taking prescription drugs should consult their physicians before taking natural remedies or any form of supplement, and this is particularly true of the elderly.
However, where the elderly are safely taking a vitamin and mineral supplement, it is extremely important that this contains more than just the RDA. Absorption problems are very common in the elderly, and this excess can make sure that they receive more than they would otherwise, if not the whole recommended dosage of the particular substance involved. Better safe than sorry, especially where an excess is not known to cause harm.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1703) Antioxidant & Cellular Energizer for Heart, Brain, Immunity & Liver
Date:
December 18, 2007 05:28 PM
Coenzyme Q10 Ultra Potent 400 mg! Antioxidant & Cellular Energizer for Heart, Brain, Immunity & Liver
1 softgel contains: Coenzyme Q10 (ubiquinone) 400mg Ubiquinone Coenzyme Q10 is a highly absorbably form of CoQ10. CoQ10 is a powerful antioxidant to help fight oxidative stress which can cause premature aging. CoQ10 is a critical enzyme for cellular energy for all muscles in the body, especially the heart muscle that beats millions of times with out stopping in a lifetime. CoQ10 can help boost brain function, boost immunity, and boost liver function. For those with gum disease, Coenzyme Q10 can support healthy gums and teeth. Have you had your Coenzyme Q10 today?
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1675) Ubiquinol
Date:
October 24, 2007 11:37 AM
Ubiquinol has powerful antioxidant actions in target cells *
Although ubiquinone (oxidized coenzyme Q10) and ubiquinol (reduced coenzyme Q10) are kept at a constant ratio within the body, the majority of the total coenzyme Q10 pool is made up of ubiquinol. In fact, when ubiquinone is taken orally, much of it appears to be rapidly converted into ubiquinol. 1,4 Ubiquinol functions as a potent antioxidant in humans, including in low-density lipoproteins (LDLs) where it protects them from oxidative damage.1,4,5 The coenzyme Q10 molecule can be found in all membranes throughout cells.6 It appears to works in conjunction with both vitamin E and vitamin C to provide antioxidant actions throughout the body.7
Coenzyme Q10 supports mitochondria to enhance cellular energy production*
Coenzyme Q10, with its widespread distribution throughout the body, plays a crucial role in mitochondrial physiology as a critical member of the electron transport chain. This transport chain, which is part of cellular respiration, leads to the formation of adenosine triphosphate (ATP), our body’s primary energy source. Levels of this key nutrient may decline as a healthy person ages.7,8 Animal studies have found that supplementation can restore normal levels in certain tissues 6, and human studies suggest that supplementing with this enzyme may have increased benefits when a person has depleted levels. 7
Coenzyme Q10 supports healthy heart functioning*
Concentrations of coenzyme Q10 are understandably high in the heart as these muscle cells require high levels of energy to constantly function optimally. A number of studies (both animal and human) strongly suggest that coenzyme Q10 supplementation is supportive for healthy heart functioning and for maintaining cardiovascular system health.7,9
Ubiquinol has been studied for safety and bioavailability in humans*
A recently published single-blind placebo-controlled study in healthy subjects found no safety concerns in people who took Kaneka’s QH ubiquinol supplement orally at doses of up to 300 milligrams daily for up to four weeks.4 Single oral doses of either 150 milligrams or 300 milligrams were given to fifteen healthy men and women, and standard laboratory testing (including hematology, blood chemistry, and urinalysis) as well as physical examination and electrocariography (EKG) results showed no clinically significant changes when tested two days after supplementation as compared to before the taking the supplement. In addition to the single dose study, 80 healthy volunteers were given either placebo, 90, 150 or 300 milligrams of ubiquinol each day for four weeks, and again no clinically significant differences were seen in any of the testing parameters after two and four weeks of supplementation, nor were there differences two weeks after discontinuation of the supplement. By monitoring levels in the blood, the authors found that ubiquinol was well absorbed.4
Studies in several animals also reveal no concern of toxicity in doses of ubiquinol up to 200 milligrams per kilogram of body weight for up to thirteen weeks.4 When compared to humans, this dose level is enormously higher than the recommended doses. Supplementation with ubiquinol appeared to be safe at even higher levels (up to 600 milligrams per kilogram body weight) in a study using a different animal. In vitro assays additionally found no safety concerns for the use of ubiquinol, as it was found to be non-mutagenic and did not cause damage to chromosomes in cells.
Safety
Suggested Adult Use: Take one softgel daily with food, or as directed by a nutritionally informed physician.
Scientific References
1. Mohr, D., V.W. Bowry, and R. Stocker, Dietary supplementation with coenzyme Q10 results in increased levels of ubiquinol-10 within circulating lipoproteins and increased resistance of human low-density lipoprotein to the initiation of lipid peroxidation. Biochim Biophys Acta, 1992. 1126(3): p. 247-54.
2. Weber, C., et al., Effect of dietary coenzyme Q10 as an antioxidant in human plasma. Mol Aspects Med, 1994. 15 Suppl: p. s97-102.
3. Okamoto, T., et al., Human serum ubiquinol-10 levels and relationship to serum lipids. Int J Vitam Nutr Res, 1989. 59(3): p. 288-92.
4. Hosoe, K., et al., Study on safety and bioavailability of ubiquinol (Kaneka QH) after single and 4-week multiple oral administration to healthy volunteers. Regul Toxicol Pharmacol, 2007. 47(1): p. 19-28.
5. Stocker, R., V.W. Bowry, and B. Frei, Ubiquinol-10 protects human low density lipoprotein more efficiently against lipid peroxidation than does alpha-tocopherol. Proc Natl Acad Sci U S A, 1991. 88(5): p. 1646-50.
6. Crane, F.L., Biochemical functions of Coenzyme Q10. Journal of the
7. Jones, K., et al., Coenzyme Q-10 and cardiovascular health. Alternative therapies, 2004. 10(1): p. 22-31.
8. Schulz, C., et al., Comparison of the relative bioavailability of different coenzyme Q10 formulations with a novel solubilizate (Solu Q10). Int J Food Sci Nutr, 2006. 57(7-8): p. 546-55.
9. Coenzyme Q10. Monograph. Altern Med Rev, 2007. 12(2): p. 159-68.
Buy Ubiquinol at VitaNet, LLC ®
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1605) Natural Coenzyme Q10 (Ubiquinone)
Date:
July 27, 2007 02:08 PM
CoQ-Quick™
Natural Coenzyme Q10 100 mg
• Supports cardiovascular function.
• Vital for the production of ATP, the energy molecule.
• Potent antioxidant.
• Addresses six of the twelve SystemiCareTM deep metabolic systems identified by Source
Naturals as critical for optimum health: Energy Production, Circulation/Heart Health, Liver/
Detox, Immunity, Cognition/Nerves, and Antioxidant Defense.
• Delicious, natural orange flavor.
One tablet contains:
Coenzyme Q10 (ubiquinone) 100 mg
Suggested Use: 1 tablet daily with a meal. Not a sublingual tablet. Place tablet on top of tongue and allow tablet to dissolve while lightly pressing tongue against the roof of the mouth. Tablet will disintegrate rapidly. Swallow CoQ-Quick contents after the tablet has disintegrated.
-- Vitanet ®
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1586) Active Coenzyme Q10
Date:
July 07, 2007 01:30 PM
Active CoQ10
The benefits of Coenzyme Q10 have become increasingly well-known. This important nutrient has been shown in clinical trials to improve heart function, reduce the side effects of certain drugs used to treat cancer, and slow the progression of serious brain diseases such as Parkinson’s disease. Now research has opened a new chapter in the CoQ10 story, highlighting the benefits of ubiquinol, the active form of CoQ10, to increase energy and stamina, and reduce some of he physical signs of aging.
In this issue of Ask the Doctor we will review the benefits of Coenzyme Q10, and discuss the differences between CoQ10 and its active form –ubiquinol.
Q. What is CoQ10?
A. CoQ10 is a natural, fat-soluble nutrient present in virtually all cells. CoQ10 also is known as ubiquinone. That’s because CoQ10 is ubiquitious and exists everywhere there is life. CoQ10 is vital to adenosine triphosphate (ATP) production. ATP is the energy-rich compound used for all processes requiring energy in the body. Although CoQ10 is produced by the body and exists in some limited dietary sources, these levels may be insufficient to meet the body’s requirements. CoQ10 levels diminish with age and as a result of dietary inadequacies and various disease states. Also, some drugs, especially a group of cholesterol lowering prescription drugs known as “statins,” (Pravachol, Zocor, Lipitor, etc.) significantly reduce CoQ10 levels in the body.
Q. What is ubiquinol? Is it the same or different from CoQ10?
A. Ubiquinol and CoQ10 are very closely related. Ubiquinone, or CoQ10, is the oxidized form of the molecule. This means it has to be converted to a non-oxidized form before it can perform its work. Ubiquinol is the active form of this nutrient. Our bodies convert CoQ10 to ubiquinol – which is the form needed to produce cellular energy. Until recently, it was not possible to use ubiquinol as a supplement because it is very unstable outside the human body. But research has now found a way to keep this molecule stable so it can be successfully taken in supplement form.
Q. If CoQ10 gets converted to ubiquinol anyway, can’t I just take CoQ10?
A. While it is true that our bodies can convert CoQ10 to ubiquinol, it isn’t true that we all do this equally well. In fact, as we age, our ability to convert CoQ10 to ubiquinol declines. And some people even have a gene that makes them less effective at this conversion than the majority of the population. IN fact, several common health issues have been associated with less than optimal ratios of CoQ10 to QH. For healthy people the ideal ratio is approximately 97% Ubiquinol to 3% CoQ10. But in people with diabetes, for example, the ratios have been found to range from 43% ubiquinol to 47% CoQ10 in mild diabetes, to only 24% ubiquinol to 76% CoQ10 in severe diabetes. These numbers are for men; the numbers for women vary by 2 to 5 percentage points.
So for older folks, the 30-50% of people who have the gene that impairs CoQ10 conversion, or for people who have serious health concerns, supplementing with ubiquinol instead of CoQ10 might be the smart choice.
Q. What are the health benefits of CoQ10 and Ubiquinol?
A. There have been many studies showing that CoQ10 is beneficial in treating and preventing heart disease and conditions such as high blood pressure atherosclerosis (hardening of the arteries), angina, and congestive heart failure (CHF). It’s been shown that heart attacks tend to occur when CoQ10 levels are low in the body. Exciting new research has found that CoQ10 in a unique delivery system supplementation may slow the progression of symptoms associated with neurological diseases such as Parkinson’s disease, ALS, Huntington’s disease and Alzheimer’s disease.
In addition, CoQ10 is beneficial for diabetes, immune dysfunction, cancer, periodontal disease, prostate cancer, and neurological disease. While the research on ubiquinol is still very new, it is reasonable to expect that its benefits will be equal to or perhaps even better than CoQ10, because it is the more active form.
Q. Why is CoQ10 especially important for preventing and treating heart disease, and for neurological diseases like Parkinson’s disease?
A. The heart and brain are some of the most metabolically active tissues in the body. Both require large amounts of uninterrupted energy, which means these tissues also need increased amounts of ubiquinol. Research has shown that many people with heart of brain diseases have serum CoQ10 levels that are lower than those of healthy people. Correcting such deficiencies often can produce significant results. However, these diseases become more common as we age – right at the time our ability to convert CoQ10 to its active form, ubiquinol, declines.
Q. How might ubiquinol be important for the heart?
A. Heart Health: A study on patients admitted to the hospital with an acute myocardial infarction (AMI) found that CoQ10 can provide rapid protective effects in patients with a heart attack if administered within three days of the onset of symptoms. Seventy-three patients received CoQ10 (120 mg/d). The study’s control group consisted of 71 similarly matched patients with acute AMI. After treatment, angina pectoris (severe chest pain signifying interrupted blood flow to the heart), total arrhythmias (dangerously irregular heartbeats), and poor function in the left ventricle (the essential chamber of the heart) were significantly reduced in the CoQ10 group compared to the placebo group. Total deaths due to sudden cardiac failure and nonfatal heart attacks also were significantly reduced in the CoQ10 group compared with the placebo group.
In another study, CoQ10 was studied in 109 patients with high blood pressure (hypertension). The patients were given varying doses of supplemental CoQ10 with the goal of attaining a certain blood level (greater than 2.0 mcg/l). Most patients were on medications to treat hypertension. Half the patients were able to stop taking some or all of their prescription drugs at an average of 4.4 months after starting CoQ10. The 9.4% of patients who had echocardiograms, performed both before and during treatment, experienced a highly significant improvement in heart wall thickness and function. This improvement was directly attributed to CoQ10 supplementation.
Congestive heart failure (CHF) is a debilitating disease that affects 5 million people in the
And Neurological Health?: A study sponsored by the National Institutes of Health showed that supplementing with CoQ10 in a unique delivery system was associated with a slowing of the progression of Parkinson’s disease. Participants were divided into 4 groups and their physical skills (coordination, walking, etc) and mental skills were evaluated. Each group then received 300 mg, 600 mg, or 1200 mg of a special form of chewable CoQ10, or a placebo. The researchers evaluated the participants after 1, 4,8, 12, and 16 months of treatment. Each participant was again scored on motor, mental, and activities of daily living skills.
The results of the study showed that the people who took the highest dosage of CoQ10-1200 mg-experienced the least decline in their physical abilities. The results were so encouraging that the researchers will be continuing with new studies, suing higher dosages to see if the results can get even better.
Huntington’s disease (HD) is a devastating and degenerative inherited disease that is always fatal. In fact, no other medication, drug, or nutritional supplement has ever been shown to cause a decline in the progression of this terrible disease. A study compared CoQ10 against remacemide (an investigational HD drug made by AstraZeneca Pharmaceuticals), in 347 HD patients who were in the early stages of the disease. Remacemide blocks glutamate, the neurotransmitter scientists think may cause the death of brain cells that occurs in Huntington’s disease. While remacemide had no effect on the progression of HD, CoQ10 showed a trend toward slowing the disease by an average of 15%. This meant the HD group taking CoQ10 was able to handle every day activities of life a little longer than the patients taking remacemide or a placebo. They also were able to focus their attention better, were less depressed, and less irritable.
The 15% slowing of decline can result in about one more year of independence of HD patients. Needless to say, the gift of an additional year of health in the lives of HD patients is incredibly significant.
Because of these impressive results, researchers are hopeful that supplemental CoQ10 will have beneficial effects for people with other neurological diseases such as ALS and Alzheimer’s disease, too. Studies are under way to confirm these effects.
Using the active form of CoQ10 helps to assure that, regardless of age or illness, the CoQ10 can have the greatest impact.
Q. What have been the results of research studies with Ubiquinol?
A. One of the most interesting effects of Ubiquinol that has been reported so far is its ability to slow the physical signs of aging. In laboratory studies, administration of stable ubiquinol to mice forestalled the changes associated with aging – rounded spine, patchy fur and irritated eyes. While the mice who received ubiquinol did not necessarily live longer than the mice that didn’t, they lived better. But it is important to note that these mice were bred to die at a young age. Human studies are needed to determined true impact on longevity.
Additionally, supplemental, stable ubiquinol has been shown to increase physical energy and stamina. In an animal study, the length of time rats were able to run on a treadmill before getting tired was measured. The same rats were then given ubiquinol and the treadmill test was repeated. The length of time the rats were able to run before tiring increased 150 times.
Q. How can one supplement have applications for neurological diseases, heart health, and even the immune system?
A. Supplements often have more than one function, especially when it’s a substance like CoQ10, which is present in all parts of the body. All nucleated cells (most cells other than red blood cells) have mitochondria and all cells require energy to function. CoQ10 is vital to ATP production. Thus, CoQ10 has applications not only in neurological (neurons or nervous system cells) and cardiac health (myocardium or heart tissue), but also for the immune system.
Q. Should I take CoQ10 or ubiquinol? How much should I take?
A. While everyone can benefit from CoQ10 or ubiquinol supplementation, it appears that ubiquinol should be the first choice for older adults, people with known genetic inefficiencies in converting CoQ10 to ubiquinol, and for people with serious heart disease or neurological diseases such as Parkinson’s disease, who are otherwise supplementing with high levels of CoQ10. For people in overall good health, a high quality CoQ10 supplement with proven absorption is a good choice.
Take 200 to 300 mg of CoQ10 or 100 mg ubiquinol daily, depending on your health history. The safety of both forms has been tested, and no significant side effects reported. Occasional mild stomach upset may occur. Taking your CoQ10 or ubiquinol with meals usually alleviates this rare effect.
Conclusion
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1583) Frequently asked Questions (FAQ)
Date:
April 21, 2007 02:48 PM
Q. What are the benefits from drinking George’s Aloe Vera liquid? A. Aloe has been used for centuries to help promote a healthy digestion and bowel movements. Soothes digestive tract. Evidence through different studies seem to indicate that beneficial properties in the Aloe help in allowing the body to rebuild mucous membranes and promotes over-all good health. Q. How often should I drink George’s Aloe Vera liquid? A. For optimum results, we recommend drinking 2 ounces in the morning before breakfast and 2 ounces in the evening before bedtime. Q. Why do you remove the polysaccharides? A. The Aloe Vera Barbadensis Miller plant has over 200 beneficial components. Although it is believed mucopolysaccharides have beneficial elements, this molecular chain is very large making it difficult for the body to utilize. The complete mucopolysaccharide chain is also the cause of rapid spoilage and breakdown of the product, which is why most other brands contain unhealthy preservatives. We breakdown the mucopolysaccharide chain extracting the sugars in order to eliminate adding any preservatives and increasing shelf life. We also theorize, through our testing, that the mucopolysaccharides in their full form are not the only “silver bullet” in helping the body heal. Our distillate contains the naturally occurring elements found in mucopolysaccharides in a low molecular weight more easily absorbed by the body. A. A distillate is a liquid that consists of pure components of a plant in its more basic form. It is unique in that a distillate is comprised of a low molecular weight thereby enabling the body to assimilate its components in the purest form at the cellular level. This occurs both internally, and through the skin’s dermal layers, at a much higher rate than would occur if the plant’s components were introduced in any other manner. Q. How long should I be drinking George’s Always Active Aloe Vera before seeing any results? A. Most people begin to see results anywhere from two weeks to one month. Remember, out bodies are continually shedding cells. It is very important to continue using even after you attain the results you are looking for. Q. Why doesn’t Georges Aloe taste bad? A. Most Aloe Vera products are slimy and have a very bitter taste. We remove the chemical antagonists such as the aloins and Anthraquinone that are mildly toxic. These antagonists can cause stomach cramping, diarrhea and in some cases vomiting. As a result, our product has no adverse flavor. Unlike other brands, our product is safe for pregnant women, nursing mothers and people at all ages. Q. Is George’s Aloe Organically grown? A. Yes! Although we do not seek the organic certification, George’s aloe is continually tested for over 50 different chemicals that may contaminate the plants. To date tests have come back negative for any contamination. Q. Does distillation just turn it to water? A. George’s is fractionally distilled, meaning it is broken down into various parts, with the undesirable elements removed. It is then re-assembled. Products such as Jack Daniels & Petroleum are distilled products and would never be confused with water. Q. Is your product diluted? A. No. It takes 23 lbs of plant to make one gallon of George’s liquid Aloe. There is no dilution, preservatives or additives. Q. Can I take to much of George’s Aloe? A. We have had no ill affects reported from people who have consumed more than the suggested “2 ounces twice daily.”
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1528) Aloe Vera’s Healing Properties Recognized 1500 years before Christ
Date:
April 21, 2007 01:53 PM
Fifteen centuries before the birth of Christ, Egyptian writings acclaimed the miracle plant we know as Aloe Vera, even then referred to as an ancient cure. Cleopatra, Alexander the Great and Aristotle were fans of this strange succulent prized for its soothing, healing and analgesic ability. Indians in central and South America used it to treat burns, kidney and bladder infections, dysentery, stomach and intestinal disorders. The pulp of the plant has been used to reduce swelling and pain from injuries, while in Mexico its used to treat arthritis and gout. For many years people have kept aloe plants around for emergency burns. We took a good look at this fascinating botanical wonder. Of the 200 plus varieties, we quickly found that only five or six fit the enzymatic structure for the cosmetic and so-called “medicinal properties” mentioned. Then while we were studying these succulents in their natural desert setting, we observed the roadrunner bird drinking the juice of the aloe vera, passing up many aloe plants to get to a particular variety, Aloe Barbadensis Miller. We then studied acre after acre and found the roadrunner “peck marks” only on one particular species. The other aloe plants were untouched. In studying this species of plant more carefully, our Houston lab found that, indeed it had much different gel than other aloes. The products now labeled as Georges “Always Active” Aloe are exclusively from Aloe Barbadensis Miller, the Roadrunners’ choice. George Warren, an Independent research chemist in Houston, Texus developed the special processing method that prevents the spoilage without diminishing the essential properties of the Aloe Vera plant. This new method completely eliminates the anthraquinones that are mildly toxic and can cause irritation to the digestive tract. Aloins are also removed, which give a bitter taste (and the Greenish color) to Aloe Vera juices along with the starches and sugars from the polysaccharide molecular chain and thus, George “Always Active” Aloe requires no refrigeration, and will not spoil in its natural state. This method adds no water, no preservatives and no chemicals of any kind. The finished product looks and tastes like spring water.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1524) Learn about Bone Health!
Date:
April 20, 2007 12:43 PM
Bone Health Approximately 44 million American women and men aged 50 and older have osteoporosis (severe bone loss) or osteopenia (mild bone loss), with women being affected about twice as often as men. At least 1.5 million fractures of the hip, vertebra (back or neck), or wrist occur each year in the United States as a result of osteoporosis, and the annual cost of treating this disorder is nearly $14 billion and rising. Unfortunately, the toll in human suffering and loss of independence is even greater. In this issue of Ask the Doctor, we will discuss the risk factors for osteoporosis and some key nutrients you can add to your diet that can minimize bone loss and reduce your chances of developing this disease. Q. What are the risk factors for osteoporosis? A. Small body frame, underweight, Caucasian or Asian race, a sedentary lifestyle, cigarette smoking, excessive alcohol or caffeine intake, high intake of carbonated beverages (especially colas), and having other family members with osteoporosis all increase personal risk of developing the disease. Certain medical conditions, including diabetes, celiac disease, hyperthyroidism, rheumatoid arthritis, chronic obstructive lung disease, hyperadrenalism, and hyperparathyroidism, are all associated with an increased risk of osteoporosis. Some medications increase the rate at which bone is lost; these include drugs prescribed for the treatment of seizures, drugs used for blood thinning, steroids such as prednisone, aluminum-containing antacids, and loop diuretics (furosemide {Lasix}). Q. Isn’t bone loss just a normal consequence of aging? A. Although bone mass normally declines after the age of 35, bone loss severe enough to cause fractures after just minor trauma (such as bump or fall) seems to be a relatively new phenomenon. Osteoporosis was rare in the late 19th century, and it was not until around 1920 that the condition began to attract attention among doctors. Since that time, the percentage of people who develop osteoporosis has continued to increase. For example, the age-adjusted prevalence of osteoporosis in Q. Can osteoporosis be prevented? A. Engaging in regular weight bearing exercise, avoiding excessive consumption of alcohol and caffeine, and quitting smoking will slow the rate of bone loss. Eating adequate, but not excessive, amounts of protein also enhances bone health. In addition, a growing body of research has shown that supplementing with various vitamins and minerals may not only help prevent, but in some cases actually reverse, bone loss. At least 15 different nutrients have been found to play a role in bone health. Q. What type of calcium is best? A. For most people, calcium salts are absorbed about the same, between 30% and 40% of the administered dose. People who low stomach acid (hypochlorhydria) should not use calcium carbonate, because that form of calcium is absorbed poorly in the absence of stomach acid. Calcium phosphate may be preferable for many older people, because phosphorus is necessary for normal bone formation, the phosphorus intake of older people is often low, and calcium supplements inhibit the absorption of phosphorus. Also, calcium bound to phosphorus is the form in which calcium in the bone is stored, and it has a much greater bone activity than other forms. Q. How much vitamin D is needed to promote strong bones? A. Because vitamin D is produced when the ultraviolet rays from the sun hit skin, people who stay out of the sun, wear sunscreen, or live in a northern latitude (such as Boston or Seattle) where less ultraviolet light reaches the skin, are at increased risk of vitamin D deficiency. In addition, aging decreases a person’s ability to synthesize vitamin D in the skin. Results from five research trials on vitamin D found that supplementation with 700-800 IU of vitamin D per day decreased the number of hip fractures by 26%, but 400 IU per day was ineffective. In addition to enhancing bone health, vitamin D improves nerve and muscle function in older people, thereby reducing their chances of falling down. Supplementation of elderly women with 800 IU of vitamin D per day has been shown to decrease the number of falls by about 50%. Q. Is that much vitamin D safe? A. The Food and Nutrition Board of the Q. Why would nutrients besides calcium and vitamin D is important? A. Bone is living tissue, constantly remodeling itself and engaging in numerous biological functions. Like other tissues in the body, bone has a wide range of nutritional needs. The typical refined and processed American diet has been depleted of many different vitamins and minerals, some of which play a key role in promoting bone health. Not getting enough of one or more of these micronutrients may be and important contributing factor to the modern epidemic of osteoporosis. In addition, supplementing with calcium may cause a loss of magnesium, zinc, silicon, manganese, and phosphorus, unless these nutrients are also provided. Q. What nutrients besides calcium and vitamin D promote healthy bones? A. Magnesium, zinc, copper, manganese, vitamin K, boron, strontium, silicon, folic acid, vitamin B6, vitamin B12, phosphorus, and vitamin C have all been shown to play a role in bone health. Following is a brief description of the role that each of these 15 nutrients play in building healthy bones. Calcium: A component of the mineral crystals that make up bone. Vitamin D: Enhances calcium absorption, prevents falls by improving nerve and muscle function. Magnesium: Important for bone mineralization (accumulation of minerals which form bones). Magnesium deficiency is associated with abnormal bone mineral crystals in humans. In an open clinical trial, magnesium supplementation increased bone mineral density by an average 5% after 1-2 years in postmenopausal women. Copper: Laboratory research has found that copper promotes bone mineralization and decreases bone loss, and that osteoporosis can develop if the diet is deficient in copper. Western diets often contain less copper than the amount recommended by the National Academy of Sciences. In a 2-year double-blind trail, copper supplementation reduced bone loss by 90% in middle-aged women, compared with a placebo. Zinc: Like magnesium, zinc is important for bone mineralization, and also has been shown to decrease bone loss. Low dietary zinc intake was associated with increased fracture risk in a study of middle-aged and elderly men. The zinc content of the diet is frequently low; a study of elderly low-income people found they were consuming only half the Recommended Dietary Allowance for this mineral. Manganese: Plays a role in the creation of the connective-tissue components of bone. Manganese deficiency in laboratory tests resulted in low bone mineral density and weak bones. Manganese deficiency may be associated with the development of osteoporosis. Boron: Supports creation of bone-protecting hormones such as estrogen, testosterone, and DHEA. Boron supplementation prevented bone loss in experimental studies. In human volunteers consuming a low-boron diet, boron supplementation decreased urinary calcium excretion by 25-33%, a change that may indicate reduced bone loss. Silicon: Plays a role in the synthesis of the connective-tissue components of bone. Silicon deficiency has been associated with bone abnormalities. In an observational study, higher dietary silicon intake correlated with higher bone mineral density. In a clinical trial, administration of an organic silicon compound increased bone mineral density of the femur (or thigh bone) in postmenopausal women. B vitamins (folic acid, vitamin B6, and vitamin B12): These three B vitamins have been shown to lower blood levels of homocysteine, a breakdown product of the amino acid methionine. An elevated homocysteine concentration is a strong and independent risk factor for fractures in older men and women. Homocysteine levels increase around the time of menopause, which may explain in part why bone loss accelerates at that time. In a 2-year double-blind trial, supplementation of elderly stroke patients with folic acid and vitamin B12 reduced the number of hip fractures by 78%, compared with a placebo. Strontium: This trace mineral is incorporated into bone and appears to increase bone strength. It also stimulates bone formation and inhibits bone breakdown. Controlled trials have demonstrated that strontium supplementation of postmenopausal women increases bone mineral density and decreases fracture risk. Vitamin K: Best known for its effect on blood clotting, vitamin K is also required for the creation of osteocalcin, a unique protein found in bone that participates in the mineralization process. The amount of vitamin K needed for optimal bone health appears to be greater than the amount needed to prevent bleeding. Vitamin K levels tend to be low in people with osteoporosis. In randomized clinical trials, supplementation of postmenopausal women with vitamin K prevented bone loss and reduced the incidence of fractures. Q. Which form of vitamin K is best? A. Two forms of vitamin K compounds are present in food: vitamin K1 and vitamin K2. Vitamin K1 (also called phylloquinone) is present in leafy green vegetables and some vegetable oils, and vitamin K2 is found in much smaller amounts in meat, cheese, eggs, and natto (fermented soybeans). To make things a little more complicated, Vitamin K2 itself can occur in more than one form. The two most important to this discussion are menaquinine-4 (MK-4, also called menatetrenone), which is licensed as a prescription drug in Research suggests that MK-7 from natto may be an ideal form of vitamin K. The biological activity of MK-7 in laboratory studies was 17 times higher than that of vitamin K1 and 130 times higher than that of MK-4. After oral administration, MK-7 was better absorbed and persisted in the body longer, compared with MK-4 and vitamin K1. Although both have shown ability to prevent osteoporosis in laboratory research, a much lower dosage (600 times lower) of MK-7 is required, compared to MK-4, to obtain beneficial effects. Thus, MK-7 has greater biological activity, greater bioavailability, and possibly more potent effects on bone, compared with other forms of vitamin K. The potential value of MK-7 for bone health is supported by an observational study from Q. Why is strontium so important in building strong bones? A. Strontium is of great interest to bone health researchers and has been studied in very high doses. Surprisingly, lower doses are not only safer for long-term supplementation, but may in fact have a greater impact on bone health than very high doses. Too little, and bone density is impaired; too much and health may be impaired. This is a case where dosing needs to be just right for optimal impact. Therefore, until more is known, it is wise to keep supplemental strontium at less than 6 mg per day. Q. Can people taking osteoporosis medications also take bone-building nutrients? A. Because nutrients work by a different mechanism than osteoporosis drugs, nutritional supplements are likely to enhance the beneficial effect of these medications. Calcium or other minerals may interfere with the absorption of biphophonates such as alendronate (Fosamax) or etidronate (Didronel). For that reason, calcium and other minerals should be taken at least two hours before or two hours after these medications. Also, it is always best to discuss the supplements you are using with your healthcare practitioner to create an integrated health plan. Final thoughts… Bone health ramifications extend beyond osteoporosis and fractures. Bone health is essential for freedom of movement, safety, comfort, independence and longevity. Weak bones do not heal well – sometimes they never heal at all. Osteoporosis-related fractures rob us of our mobility and consign thousands of Americans to walkers and wheelchairs every year. In fact, 40% of people are unable to walk independently after a hip fracture, and 60% still require assistance a year later. The most terrible consequence of fractures related to osteoporosis is mortality. The impairment of the ability to move around freely can cause pneumonia and skin damage leading to serious infections. It is estimated that suffering a hip fracture increases the risk of dying almost 25%. Making bone health a priority now will allow you to reap health dividends for many years to come.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1523) CoQ10 for Heart Health
Date:
March 28, 2007 12:39 PM
CoQ10 for Heart Health
More than 40% of all deaths in the
One of the most – if not the most – important things people can do to improve their overall health and life expectancy is to improve their heart health. Diet, exercise, and the wise use of dietary supplements can improve heart health dramatically. One dietary supplement that’s extremely beneficial to heart health is coenzyme Q10 (CoQ10).
Q. What is CoQ10?
A. CoQ10 is a natural, fat-soluble nutrient present in virtually all cells. CoQ10 also is known as ubiquinone. That’s because CoQ10 is ubiquitous and exists everywhere there is life. CoQ10 is vital to adenosine triphosphate (ATP) production. ATP is the energy-rich compound used for all energy-requiring processes in the body. Although COQ10 is produced by the body and exists in some dietary sources, these levels may be insufficient to meet the body’s requirements. CoQ10 levels diminish with age and as a result of dietary inadequacies and various disease states. Also, some drugs, especially a group of cholesterol-lowering prescription drugs known as “statin,” (Pravachol, Zocor, Lipitor, etc.) significantly reduce CoQ10 levels in the body.
Q. For what health conditions is CoQ10 used?
A. CoQ10 is beneficial in treating and preventing CVD and conditions such as high blood pressure, atherosclerosis (hardening of the arteries), angina, and congestive heart failure (CHF). It’s been shown that heart attacks tend to occur when CoQ10 levels are low in the body. In addition, CoQ10 is beneficial for diabetes, immune dysfunction, cancer, periodontal disease, prostate cancer, and neurological disease.
Q. Why is CoQ10 especially important to heart health?
A. The heart is one of the most metabolically active tissues in the body. In the average person, the heart propels 2,000 gallons of blood through 65,000 miles of blood vessls by beating 100,000 times each day. Thus, it requires large amounts of uninterrupted energy. Heart cells have a greater number of mitochondria, and subsequently, more CoQ10 than any other type of cell. Each heart cell can have thousands of mitochondria to meet these energy demands.
Mitochondria are highly specialized structures within each cell and are often referred to as cell powerhouses. These tiny energy-produces produce 95% of the energy the body requires. The number of mitochondria in a cell depends on its function and energy needs. A cell’s ATP production is dependent on adequate amounts of CoQ10.
Heart disease patients are commonly CoQ10 deficient. Correcting such deficiencies often can produce amazing results. The presence of supplemental CoQ10 is a key to the heart’s optimum performance.
In people who have had a heart attack (myocardial infarction), CoQ10 assists in repairing the heart muscle and restoring heart function. This is due to increased ATP production.
Q. What studies support this fact?
A. A 1998 study found CoQ10 can provide rapid protective effects in patients with a heart attack if administered within three days of the onset of symptoms. The study focused on patients admitted to the hospital with an acute myocardial infarction (AMI) diagnosis. Seventy-three patients received CoQ10 (120 mg/d). The study’s control group consisted of 71 similarly matched patients with acute AMI. After treatment, angina pectoris (severe chest pain signifying interrupted blood flow to the heart), total arrhythmias (dangerously irregular heartbeats), and poor function in the left ventricle (the essential chamber of the heart) were significantly reduced in the CoQ10 group compared to the placebo group. Total deaths due to sudden cardiac failure and nonfatal heart attacks also were significantly reduced in the CoQ10 group compared with the placebo group.
In another study, CoQ10 was studied in 109 patients with high blood pressure (hypertension). The patients were given varying doses of supplemental CoQ10 with the goal of attaining a certain blood level (greater than 2.0 mcg/l). Most patients were on medications to treat hypertension. Half the patients were able to stop taking one to three antihypertensive drugs at an average of 4.4 months after starting CoQ10. Only 3% of patients required the addition of one antihypertensive drug. The 9.4% of patients who have echo cardiograms, performed both before and during treatment, experienced a highly significant improvement in heart wall thickness and function. This improvement was directly attributed to CoQ10 supplementation.
Congestive heart failure (CHF) is a debilitating disease that affects 5 million people in the
Q. I’ve heard that CoQ10 can also help people who have neurological diseases. Is this true?
A. Yes, it is. CoQ10 has been studied for its ability to improve the health of individuals with amotrophic lateral sclerosis (ALS), Parkinson’s disease, and Huntington’s disease. A recently completed study sponsored by the National Institutes of Health showed that CoQ10 caused a slowing of the progression of Huntington’s disease, a devastating and degenerative disease that is always fatal. In fact, no other medication, drug, or nutritional supplemental has ever been shown to cause a decline in the progression of this terrible disease.
The study compared CoQ10 against remacemide (an investigational HD drug made by AstraZeneca Pharmaceuticals), in 347 HD patients who were in the early stages of the disease. Remacemide blocks glutamate, the neurotransmitter scientists think may cause the death of brain cells that occurs in Huntington’s disease. While remacemide had no effect on the progression of HD, CoQ10 showed a trend toward slowing the disease by an average of 15%. This meant the HD group taking CoQ10 was able to handle every day activities of life a little longer than the patients taking remacemide or a placebo. They also were able to focus their attention better, were less depressed, and less irritable. The 15% slowing of decline means that CoQ10 can result in about one more year of independence for HD patients. Needless to say, the gift of an additional year of health in the lives of HD patients is incredibly significant.
Because of these impressive results with HD, researchers are hopeful that the studies of CoQ10 in those with ALS and Parkinson’s disease will similarly have a positive effect on the symptoms and/or progression of these neurological disorders, too.
Q. Why is it crucial for a CoQ10 supplement to cross the blood-brain barrier?
A. The brains’ blood vessels are composed of cells with extremely tight junctions. These junctions form the blood-brain barrier, which restricts what can pass from the bloodstream into the brain. While this barrier protects the brain, it can be a significant obstacle to central nervous system therapy. To leave the bloodstream and reach the brain cells, a substance must pass through the tightly connected cells of the capillary walls. Only substances with unique solubilities or those with a transport system can cross the blood-brain barrier to a significant degree. As a result, crossing the blood-brain barrier presents a significant challenge to supporting neurological health.
While most CoQ10 supplements enter the bloodstream and increase blood serum levels, only special forms of CoQ10 have been shown to cross the blood-brain barrier. For CoQ10 to enter the mitochondria within the brain, CoQ10 must first cross the blood-brain barrier to produce significant neurosupportive clinical results.
Q. How can one supplement have applications for neurological diseases, heart health, and even the immune system?
A. Supplements often have more than one function, especially when it’s a substance like CoQ10, which is present in all parts of the body. All nucleated cells (most cells other than red blood cells) have mitochondria and all cells require energy to function. CoQ10 is vital to ATP production. Thus, CoQ10 has applications not only in neurological (neurons or nervous system cells) and cardiac health (myocardium or heart tissue), but also for the immune system.
Q. Are all CoQ10 supplements created equal? Doesn’t CoQ10 just have to get into the bloodstream to be effective?
A. There are some important distinctions among CoQ10 products, as they vary greatly in quality and absorbability. It’s crucial to find a CoQ10 product that’s:
1. Scientifically shown to absorb through the digestive tract, cross cellular membranes, and increase mitochondrial levels of CoQ10. Chewable forms of CoQ10 provide rapid bioavailability and absorption. Serum level determination of CoQ10 in the bloodstream is not necessarily the most important measure of efficacy. For a CoQ10 supplement to be fully effective, it must cross the cellular barrier and raise intracellular CoQ10 levels. A key indicator of effective CoQ10 supplementation is its presence in cell mitochondria.
2. The natural form of CoQ10. The natural process uses living organisms. CoQ10 also can be synthesized by a chemical process, which produces a distinctly different product that contains chemical compounds not found in the natural form.
3. Formulated with ingredients that provide the transport system CoQ10 needs to cross cellular membranes and the blood-brain barrier. Not all forms of CoQ10 have been scientifically proven to cross cell membranes and the blood-brain barrier. Some prestigious groups that have investigated this issue include researchers at
4. Studied by respected organizations, with research published in peer-reviewed journals by reputable scientists.
Q. How much CoQ10 should I take?
A. Take 100 to 200 mg of CoQ10 daily, depending on your family history of heart disease and personal heart disease experience.
CoQ10’s safety has been evaluated. Dosages in studies have ranged from 100 mg to 1,200 mg per day. To date, no toxicities have been reported. Occasional mild stomach upset may occur. Taking CoQ10 with meals usually alleviates this rare effect.
Q. What are some other heart-friendly supplements?
A. CoQ10 is an excellent supplement for overall cardiovascular health, as in L-carnitine. L-carnitine is the naturally occurring form of carnitine that’s found in food and synthesized in the body. Much of the body’s L-carnitine is found in the heart and skeletal muscle, tissues that rely on fatty acid oxidation for most of their energy. Nearly 70% of the energy needed for heart function is derived from fatty acid breakdown. Proper L-carnitine supplementation transports fatty acids into cell mitochondria, where it’s burned for energy. L-carnitine is an excellent addition to CoQ10, especially for people with heart disease, and has been shown to improve many symptoms associated with CVD. In one study, people who had experienced one heart attack received either L-carnitine or placebo. The L-carnitine group had a statistically significant reduction in second heart attacks, and improved overall survival.
Q. What supplements support healthy blood pressure and cholesterol?
A. In addition to maintaining overall cardiovascular health, it’s also important to address your essential fats/lipids levels and healthy circulation/blood pressure. Fish oil supplements can significantly reduce blood pressure, cholesterol, and homocysteine levels. Choose a supplement that’s a rich source of EPA and DHA, omega-3 fatty acids naturally obtainable in fish oil. Find a product that’s been clinically studied and purified to ensure it contains the beneficial active constituents of the whole oil, while removing any dioxins, DDT, PCBs, or heavy metals, toxins present in some commercial fish oil preparations. An enteric-coated garlic product that provides a minimum of 5,000 mcg of beneficial allicin supports healthy blood pressure and circulation. And magnesium, niacin, vitamin E, folic acid, hawthorn extract, and L-cysteine provide overall nutritional support to the heart and vascular system.
Conclusion
CoQ10 is not the only answer to the complex issues of heart disease, neurological disease, or immune dysfunction; however, research indicates that it’s a bigger piece of the puzzle than physicians and scientists ever imagined. The more we study this naturally occurring compound, the more benefits we find.
The key to this supplement is the manufacturing quality. For safety and overall effectiveness, use a CoQ10 product that’s supported by product-specific research from reputable institutions. Choose tested products from a well-respected company to increase your potential to achieve and maintain heart and blood vessel health.
Supplementation with clinically studied products can have a major impact on your heart’s health and strength. However, no supplement replaces the need to eat a healthful diet low in refined foods (especially sugar), and saturated fats, and to exercise your most important muscle – your heart – on a regular basis.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1501) Neurological Health and CoQ10
Date:
February 25, 2007 12:06 PM
Between 1946 and 1965, 78 million Americans were born, creating the largest number of children in U.S. history. This Baby Boom generation has greatly influenced the makeup of American society and undoubtedly w ill continue to do so. Thanks to good nutrition and health care, Baby Boomers are aging well and have an excellent life expectancy. For the first time in history, we have more people turning 60 every day, and record numbers of adults reaching their seventh decade. As a result, neurological diseases associated with aging, such as Parkinson’s disease, are becoming major health care concerns. The good news is CoQ10 has applications for neurological diseases, in addition to its better known use for cardiovascular diseases. Q. What is CoQ10? A. CoQ10 is a natural, fat-soluble nutrient present in virtually all cells. CoQ10 also is known as ubiquinone (existing everywhere there is human life). CoQ10 is vital to the production of adenosine triphosphate (ATP). ATP is the energy-rich compound used for all energy-requiring processes in the body. Q. Isn’t CoQ10 a supplement for heart health? A. Yes, it is. Because the heart requires lots of ATP to meet its high energy needs, CoQ10’s function in heart health is well understood. Numerous clinical studies have demonstrated that when individuals with heart disease take CoQ10, their symptoms improve, sometimes quite dramatically. Supplemental CoQ10 improves the heart’s pumping ability, improves blood circulation, increases tolerance to exercise, and improves the heart’s muscle tone. CoQ10 also is a powerful antioxidant and protects heart tissue from free-radical damage. Q. How does CoQ10 affect brain health? A. CoQ10 works in the brain the same way it works elsewhere in the body: it’s essential to ATP production. Nearly all human cells contain tiny structures called mitochondria. Mitochondria are referred to as cell powerhouses because they produce cellular energy. Depending on what each cell’s job is. There can be several thousand mitochondria in one cell. If a cell needs a lot of energy, it will have more mitochondria. This explains why heart cells contain so many mitochondria; the continual pumping of blood requires continual ATP production. The brain also requires huge amounts of uninterrupted energy to regulate, integrate, and coordinate ongoing nervous system transmissions. To meet this need, ATP production within the mitochondria of brain cells is vital. Since CoQ10 exerts such a powerful influence on heart cells in ATP production, it was a natural progression for scientists to wonder how it affects brain cells. Brain and nervous system research led to the conclusion that the same intracellular principles apply. CoQ10 is produced in the body to assist in ATP production. Without it, ATP cannot be produced. The most important discovery regarding CoQ10 and the brain is that CoQ10, when formulated with certain ingredients, can cross the blood-brain barrier and enter the brain’s mitochondria. If large amounts of CoQ10 can get into the brain cell’s mitochondria, its ability to make ATP is greatly enhanced. Q. What is the blood-brain barrier and why is it important? A. The blood-brain barrier is a unique anatomical structure. The cells that make up the blood vessels that provide blood to the brain are extremely close together. This greatly restricts what can leave the bloodstream and enter the brain. While the blood-brain barrier protects the brain and spinal cord from potentially toxic substances, it also can be a significant obstacle to therapy of central nervous system disorders. Only substances with certain solubilities or those that have a transport system can cross the blood-brain barrier to a significant degree. Obtaining optimal absorption of CoQ10 is difficult. The CoQ10 molecule is large and inflexible. The easiest and least expensive way to increase absorption levels is with the use of harsh solvents such as propylene glycol. However, at higher doses, these types of chemicals are considered dangerous (neurotoxic) to the person with a serious neurodegenerative disease. It is more difficult, as well as more expensive (considering raw materials, research, and proper manufacturing methods) to promote absorption with less harmful alternatives. However, reputable companies ensure that their products are safe for all their customers. Look for CoQ10 products formulated with vitamin E and other safe ingredients such as Micosolle. Nearly all CoQ10 supplements enter the bloodstream. But, only CoQ10 supplements with special formulations have been scientifically shown to enter the mitochondria and cross the blood-brain barrier. Q. If CoQ10 is made in the body, why take supplements? A. While CoQ10 is synthesized in the body, these levels may be insufficient to meet the body’s requirements. Researchers have discovered CoQ10 levels diminish with age and as a result of dietary inadequacies and various disease states. They also have determined some medications significantly reduce CoQ10 levels in the body. Although CoQ10 exists in some dietary sources, it may not be realistic to obtain CoQ10 through food alone. For example, it would take approximately 3 pounds of sardines, 7 pounds of beef, or 8 pounds of peanuts to equal 100 mg of supplemental CoQ10. Q. How does CoQ10 help people with Parkinson’s disease? A. CoQ10 seems to have several beneficial actions in the illness. Researchers have looked at mitochondria in brain cells and determined people with Parkinson’s disease have reduced activity of Complex I in the electron transport chain. Recent research has proposed the reduced activity of Complex I interferes with the brain-signaling chemical dopamine. Stored and newly synthesized dopamine is depleted. The dopamine depletion causes nerve cell degeneration. A recent clinical study involved 80 patients with Parkinson’s disease (both men and women). The researchers first evaluated all the participants to establish scores for basic motor skills (measuring the ability to control physical movements such as walking), mental status (whether the person was depressed or experiencing memory loss) and the activities of daily living (whether the person was experiencing difficulty with handwriting, dressing themselves, using utensils such as knives and forks, and so on). This scale is known as the Unified Parkinson’s Disease Rating Scale (UPDRS). This process is known as establishing “baseline values,” that is, the condition of the patient before receiving any treatment. Participants were divided into 4 groups. Each group received either 300 mg, 600 mg, or 1200 mg of the special form of CoQ10, or a placebo. The researchers observed the participants for 16 months. The results of the study showed that all the participants who received CoQ10 had smaller declines in function compared to the placebo group, but the smallest decline was experienced by the group taking the highest amount of the special form of CoQ10. The most significant results were noted specifically in the activities of daily living scores by the people taking 1200 mg of CoQ10 daily. These people retained better ability to feed and dress themselves, speak, walk, and bathe or shower by themselves. They maintained greater independence for a longer time. Parkinson’s disease, as with other neurodegenerative diseases, robs the sufferer of their ability to control the movements of their own body and care for themselves. Supplementation with CoQ10, while not a cure, is the first intervention that showed a slowing in the progressive deterioration of the function associated with this disease. Q. What were the results of clinical research on Huntington’s Disease? A. A randomized, double-blind, placebo controlled study respected type of study, was conducted at the University of Rochester. All of the 347 Huntington’s disease (HD) patients were experiencing some HD symptoms, but were still in the early stages of the disease. The patients (who did not know which drug they were receiving) were randomly assigned to four different treatment groups: 25 percent received Remacemide, 25 percent received CoQ10, 25 percent received both, and 25 percent received a placebo, or sugar pill. The researchers, who also did not know which patients got which drug, watched and recorded their progress for two and one-half years. Remacemide is a new drug made by Astra Seneca that blocks the neurotransmitter glutamate in the brain, that has long been suspected of contributing to the death of brain cells in Huntington’s disease. Unfortunately, in the CARE-HD study, Remacemide had no effect on the progression of the disease in patients in the early stages. However, the individuals who received 600 mg of CoQ10 per day experienced some slowing of the disease progression. They were able to manage daily activities, such as meal preparation, housekeeping tasks, and personal care longer than those not on CoQ10. They were also able to focus their attention better and were less depressed and irritable. The portion of the studied patients receiving 600 mg of CoQ10 per day experienced a 15 percent decline in the progression of HD. According to the researchers conducting the study, a 15 percent decline in the progression of HD would roughly translate into approximately one more year of independence for patients. This is the very first study from more than a dozen Huntington’s disease patient trails that showed any modification of the course of the illness. Of note, the effects of the CoQ10 had not abated at the end of the research study. That is, the benefit of using CoQ10, 600 mg per day, was still increasing; this suggests that the longer a patient supplements with CoQ10, the greater the decline in the progression of HD. The next phase of the CARE-HD research will test a higher dose of CoQ10 (1200 mg or more per day), with more patients (over 1000), for a longer period of time (approximately 5 years). This study should improve our understanding of the optimal dose and the total achievable decline in the progression of HD. The CoQ10 product used in the CARE-HD study was designated an Orphan Drug by the FDA. The product utilizes a proprietary, patent-pending delivery mechanism, which is proven to be safe and tolerable at high doses for people suffering from neurodegenerative diseases, substantially improving brain tissue levels of CoQ10. Q. What other diseases could benefit from CoQ10 supplementation? A. Studies show CoQ10 levels are greatly reduced in Alzheimer’s patients. Mitochondrial abnormalities also are noted; however, research has yet to determine how or why this occurs. Some scientists believe damage to mitochondria is an early feature of the disease. Free-radical damage also is a feature of Alzheimer’s. In a study of 27 Alzheimer’s patients, subjects were given 60 mg of CoQ10, 150 mg of iron, and 180 mg of vitamin B6 daily. Each patient’s mitochondria activity was effectively activated. All patients continued to experience gradual decline. However, researchers believed that with this combination, the progression was much slower and allowed the patients to experience 1 to 2 years of extended good health. ALS (also known as Lou Gehrig’s disease) is a progressive, fatal, neurological disease. It occurs when the nerve cells in the brain that control voluntary movement gradually degenerate. Investigation of CoQ10 in individuals with ALS is just beginning. Researchers at the Eleanor and Lou Gehrig ALS Center at Columbia University recently conducted a small clinical pilot trial of CoQ10 in ALS. The study was an open label study, which meant that everyone enrolled received CoQ10, 400 mg three times per day. Of the 16 patients originally enrolled, nine patients completed the study. Six of these nine patients experienced some benefits. The patients declined from 0 – 25 percent in functional scores, 6 percent in strength, and 10 percent in breathing ability. These scores reflect a positive trend compared to the 50 percent decline that is seen in the natural history of ALS over the same period of time (5 to 9 months). Citing the need to conduct more studies of the effectiveness of CoQ10 for people with ALS is rapidly and efficiently as possible to get answers to patients and clinicians, another clinical trial is currently underway at the Gehrig ALS Center. This is a pilot study to determine if CoQ10 has short-term effects on motor nerves in the brain using magnetic resonance spectroscopy (MRS). The researchers are going to try to “see” if CoQ10 can change the chemical sin the brain’s upper motor nerves of people with ALS, an important next step of the investigation. Q. Can taking CoQ10 prevent neurodegenerative disease? A. To date, there have been no studies or research examining whether CoQ10 can prevent these diseases. Alzheimer’s disease prevention is being clinically investigated. Researchers have determined that people who take certain anti-inflammatory medications seem less likely to develop the illness. A large, multi-centered trial is studying this connection. Q. How much CoQ10 should I take? A. Depending on your family history of neurological disease and your disease experience, studies show benefits at doses of 100 to 200 mg of CoQ10 daily. Some studies used doses of up to 1,200 mg per day. CoQ10’s safety has been evaluated. To date, no toxicities have been reported. Mild stomach upset may occur. Taking CoQ10 with meals usually alleviates this rare effect. Q. What should I look for in a CoQ10 supplement? A. Use products which have a strong clinical research track record, supported by product-specific research from reputable institutions, and have been proven to be safe, tolerable and effective in treatment of neurodegenerative diseases. The CoQ10 product you choose should be proven to: be absorbed, enter the blood stream, cross the blood brain barrier and increase mitochondrial levels of CoQ10. If the product you are considering does not have evidence to support these points, keep looking. Once you have found a candidate, examine the product’s safety and efficacy record for neurodegenerative diseases- if the product has not been proven to be safe and effective, keep looking. Good products exist; however, caveat emptor. Conclusion CoQ10 supplementation for people with neurodegenerative diseases is supported by contemporary clinical research. CoQ10 is certainly not the only answer to the complex issues of management and treatment of these types of diseases. However, research indicates that it is a bigger piece of the puzzle than physicians and scientists ever imagined. As we continue to study this naturally occurring compound, we are finding more and more benefits to the body. All CoQ10 is not created equal. For safety and overall effectiveness, use a CoQ10 product that is supported by product-specific research from reputable institution, which is proven to be safe, tolerable and effective at high doses; deviating from this set of criteria may do more harm than good for people with these serious illnesses. Choose clinically tested products from a well-respected company and increase the potential to achieve and maintain brain and neurological health.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1459) For Better Heart Health ...
Date:
February 06, 2007 12:57 PM
Nutrients Every Heart Needs
High blood pressure. High cholesterol levels. Ever increasing stress. All are factors related to the development of heart disease – the leading cause of death for both men and women. In fact, 1 in 2 women in the
Fortunately, heart disease is a problem you can do something about. Proven ways to prevent or mitigate the effects of heart disease include taking targeted nutritional supplements, making changes in the foods we eat, exercising most days of the week, drinking in moderation, eliminating tobacco use and adapting a positive attitude. Research shows that those of us who are often angry and depressed have more heart disease than people that live their lives with a more positive outlook.
In this Ask the Doctor, we’ll talk about specific nutritional supplements that are heart healthy, whether your goal is to prevent heart disease or reduce the effects of heart disease if you currently have it.
Q. I am trying hard to live a healthier life. But it all seems so overwhelming. How do I start?
A. It may help to know that you’re not alone in feeling overwhelmed. Lots of people feel this way. This is why the Centers for Disease Control and the American Heart Association are both urging people to prevent heart disease by identifying their individual health risk factors.
A risk factor is an indicator of whether or not you may develop a certain health condition. In heart disease prevention, there are two kinds of risk factors. There are risk factor you can control – such as diet, exercise, and the supplements you take. There are also risk factors you can’t change or control –your age, race, and gender, as well as your family’s history of heart disease.
Examples can be really helpful. Let’s follow three adults – Fred, Jane, and Earl – and determine their risk factors.
Low Risk
Fred is 32, single, has a job he loves, has an optimistic attitude about his life, and works out 5 days a week. Most days Fred’s diet is fruits, vegetables, whole grains and low fat. Occasionally Fred will eat a cheeseburger and fries when he watches the game with his buddies. Fred’s risk factors are his male gender and the occasional high fat content in his diet.
Moderate Risk
Jane is 55, a lawyer, married, and has a very stressful job. Jane eats lots of salads, fruits, and whole grains. However, her job requires her to work long hours which leaves little time to exercise. Jane is for the most part happy with her life, but her work stress had led to times of negativity. Her father had a heart attack when he was 56. Jane’s risk factors include her age (greater than 50), negativity from job stress, lack of regular exercise, and a family history of heart disease.
High Risk
Earl is 65, married, and has just retired from a job he hated. He spends most of his day watching TV and eating potato chips and other high fat, salty snacks. Earl has told his friends and family since he worked so hard for so long, he is sure to drop dead soon after retiring. He has high cholesterol and high blood pressure. Earl’s father had a heart attack and died when he was 73. Earl’s risk is his male gender, age (greater than 50), sedentary lifestyle, poor diet, negative outlook on life, high cholesterol and high blood pressure, and a family history of heart disease.
Q. OK, it’s pretty easy to see that Fred needs to watch his diet, Jane needs to exercise more, and Earl needs lots of help. But, which supplements should they take?
A. The Whole Heart Nutrition chart is an easy way to determine the supplements each risk level needs. As you can see, everyone wanting to prevent heart disease – Fred, Jane, Earl, you, and I – need to take quality heart formula multivitamin, garlic, and a fish oil supplement providing Omega-3 fatty acids. CoQ10 is also a smart choice for complete heart heath support.
Q. Why do we all need to take a “heart multivitamin”? Why can’t we take a regular multivitamin to prevent heart disease?
A. Since the human heart simply cannot function without adequate amounts of certain vitamins and minerals, it seems logical that a multivitamin would be the foundation of good nutrition for your heart. Heart-health formulated multivitamins provide the exact nutrients needed to prevent heart disease.
That’s why we need to take a specially formulated heart-focused multi-vitamin. The cells and the tissues that make up the heart must have vitamins C, A, and E, as well as B1, B6, and B12 to function. Folic acid, the little B vitamin that is so crucial in preventing spina bifida (a birth defect), breast cancer, and Alzheimer’s disease is also needed to keep heart muscles strong. The B vitamins and folic acid are very important to heart health because they help lower homocysteine levels. Homocysteine is a potential and emerging cardiac risk factor,
Magnesium is a mighty mineral and healthy hearts need it every day. Aloha lipoic acid, a fatty acid, provides protection against heart cholesterol and high blood pressure. Lutein and lycopene are all-natural nutrients and keep our arteries free from the buildup of plaque, a condition linked to heart attacks and strokes.
Multivitamins formulated with these exact vitamins, minerals, and nutrients will work with medications often prescribed to treat heart disease and provide the nutrition our hearts need.
Q. Don’t all multivitamins work with medications prescribed to treat heart disease?
A. Many multivitamin formulas contain herbs and other nutrients that can interfere with prescription medications, especially mediations prescribed to treat heart disease. One multivitamin does not fit all.
The more risk factors you have, the greater your chance of developing heart disease.
Q. What can garlic supplements do for Fred, Jane and Earl or other people with low to high risk factors?
A. Garlic supplements have a very long and very successful history of preventing premature death from heart attacks. Lately, however, there have been some conflicting news stories about supplemental garlic’s ability to lower high cholesterol and high blood pressure – the causes of heart disease and death. That’s because many different garlic supplements have been used in these studies – garlic oil, garlic powder, aged garlic extract, and supplements made from fresh garlic. They have all been studied clinically for their effects in heart disease.
The best garlic supplements (and the ones that showed the best effects in garlic studies) contain alliin, which is then converted to allicin. Allicin is the compound that lowers harmfully high cholesterol levels and dangerous blood pressure readings. Allicin is also responsible for garlic’s characteristic odor. Because alliin is very stable when dry, properly prepared and enteric coated fresh garlic preparations preserve the allicin-producing action until the garlic mixes with the fluids of the intestinal tract. Fresh garlic extract’s enteric coating also prevents garlic breath. In contrast, aged garlic contains absolutely no allicin or allicin potential. This fact is probably responsible for the poor results noted in lowering cholesterol and blood pressure from aged garlic preparations.
The most effective garlic supplements are made from fresh garlic, enteric coated, and provide a daily dose of at least 10 milligrams (mg) alliin or a total allicin potential of 4,000 micrograms (mcg). Taking a once-daily garlic supplement that delivers 4,000 mcg of allicin will lower Jane’s and Earl’s high blood pressure and Earl’s high cholesterol, naturally and effectively.
Whole Heart Nutrition
Each additional risk factor requires additional supplements or increased doses for protection from heart disease.
Q. What about fish oil supplements? I know they can prevent heart disease but I’ve also heard they contain harmful substances, too.
A. You’re right on both counts. But, there are excellent fish oil supplements naturally loaded with Omega-3 fatty acids, powerful nutrients that prevent heart disease, that are also certified free of harmful contaminants.
In the 1980s, researchers first began noticing the native Inuit (Eskimo) populations of Greenland and
Research has shown that the Omega-3 fatty acids in fish oil supplements can:
-Reduce the risk of arrhythmias, lethal heartbeat rhythms that cause sudden death.
-Lower the levels of triglycerides, fats in the blood that can increase a person’s
risk of dying from a heart attack, even if a person’s cholesterol levels are normal.
-Slow atherosclerosis – the growth of harmful plaque on artery walls.
Atherosclerosis develops over many years. If the plaque growth is slow and
stable, chances are low that a heart attack will result. However, rapidly growing
or unstable plaques can rupture. The body responds with inflammation, which
causes blood clots to form. These blood clots block the artery and cause a heart
attack.
-Keep blood pressure levels low. Many people have high blood pressure for years
without knowing it. That’s because it has no symptoms. Uncontrolled high
blood pressure can lead to stroke, heart attack, heart failure, and kidney failure.
While 25% of Americans have high blood pressure, nearly one-third of these
people don’t know they have it. This is why high blood pressure is often called
the “silent killer.”
You can get all of this heart disease preventive protection from just 600-1800 mg of fish oil. It’s pretty simple to see why Fred, Jane, Earl, and you and I need to take fish oil supplements every day.
However, it is absolutely critical that the fish oil supplement you take is free of contaminants and guaranteed fresh! Make sure that the manufacturer of the fish oil supplement you buy is able to provide documentation of purity in their product. Supplements should contain no detectable dioxin (a widely used toxic preservative), DDT (a toxic insecticide), PCBs (polychlorinated biphenyls) or heavy metals such as mercury and lead.
Before you buy any fish oil supplement, ask the clerk if you can open the bottle or jar and smell the contents. A fishy smelling fish oil supplementation means it is rancid. Rancid fish oil is not going to help your heart at all and may actually hurt it.
Q. That leaves CoQ10. Why is it important for Jane and Earl?
A. CoQ10, also known as ubiquinone, is the premier heart supplement! CoQ10 is part of our energy producing system. It works directly in the mitochondria of each cell. Mitochondria are highly specialized structures within each cell and are often referred to as powerhouses. These tiny energy producers generate 95% of the energy the body requires. The number of mitochondria in a cell depends on its function and energy needs. The heart has very important functions and requires a vast amount of energy. Thus, the heart has a lot of mitochondria or little powerhouses.
CoQ10 is incredibly crucial to the health of our hearts. Especially to hearts that are pumping blood with too much cholesterol. But, in a dangerous paradox, CoQ10 levels can become dangerously depleted when physicians treat high cholesterol in their patients with certain medications. The so-called “statin” drugs (Mevacor/lovastatin and Crestor/rosubastatin are two examples) are powerful and medications prescribed to lower harmful cholesterol levels. However, one very harmful side effect they share is that they deprive cells of CoQ10. While some physicians are aware of this serious side effect and tell their patients to take at least 400 mg of CoQ10 each day, most are not. The result? Any good the statin drugs may be doing is actually negated by their depletion of CoQ10.
Q. How does CoQ10 actually work? Has it been studied in heart disease?
A. Yes, it has! CoQ10 has been extensively studied in heart disease. This natural nutrient is present in every nucleated cell in our body (the only cells that don’t contain CoQ10 are red blood cells). Heart cells, however, are absolutely loaded with CoQ10. Its job is fairly simply – CoQ10 is vital to the production of adenosine triphosphate (ATP), the compound our body uses for 95% of its energy needs.
In 1998, 144 patients who had been admitted to the hospital after a heart attack, participated in a CoQ10 study. Half of the patients received 120 mg of CoQ10 a day in addition to the usual treatments given to heart attack patients. The other half, the control group, received the usual treatments and a placebo, but no CoQ10.
The results showed that the group taking CoQ10 had less irregular heartbeat, experienced less angina (a type of heart pain), and had much better function in the left ventricle (the most essential chamber of the heart), compared to the placebo group. Total deaths due to sudden heart failure or another heart attack were also reduced in the CoQ10 group.
Q. What if I have already been diagnosed with Congestive Heart Failure? Will CoQ10 still help me?
A. CoQ10 has been proven in study after study to help slow down the destruction that occurs in congestive heart failure (CHF), a serious heart disease, and heal the heart muscles damaged by heart attacks. In fact, heart attacks often occur when the body’s CoQ10 levels are low.
In a CHF study, patients received 100 mg of CoQ10 or a placebo twice daily for 12 weeks. Before and after the treatment period, the researchers introduced a catheter into the right ventricle of the patients’ hearts to determine the degree of muscle damage CHF had caused. In the group who took CoQ10, the pumping ability of the heart improved significantly. The placebo group’s hearts did not. The researchers conducting the study recommended that people with CHF add CoQ10 to the other medications they need to take to stay alive and well.
Q. Are some types of CoQ10 better than others?
A. Indeed they are. CoQ10 products are not created equally. The key to this natural medicine is the quality of the manufacturing. Take a CoQ10 supplement that’s been used in research conducted by prestigious universities (it will tell you this right on the label). Researchers want the best CoQ10 for their studies. You want the best CoQ10 for yourself and your loved ones.
The best CoQ10 has to meet the following criteria:
1. Must be easily absorbed during the digestion process so that it can get into the
bloodstream.
2. Must reach the mitochondria in the cell.
3. Must be proven effective in studies.
4. Must be safe and free of impurities.
Q. It sounds as if CoQ10 is only for people with moderate or high risk factors. Can others benefit from this supplement?
A. Many people, including those like Fred with low risk factors or no risk of heart disease take CoQ10 every day. CoQ10 supplements may reduce your risk of cancer, prevent gum disease, and help certain nerve cells work more effectively.
Conclusion
Understanding your personal risk factors, making it better lifestyle choices, taking a multivitamin formulated for your heart, an enteric-coated fresh garlic supplement, fish oil supplement with Omega-3 fatty acids, and CoQ10 – the heart’s super-nutrient – can help keep your heart healthy and strong.
Helen Keller, the famous lecturer and author, who was both blind and deaf wrote, “The best and most beautiful things in the world cannot e seen or even touched. They must be felt with the human heart.”
Healthy hearts have the most opportunities to “feel” the best and are the most beautiful thing our world has to offer.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1449) Mangoni - Complete SuperFruit Food 1oz equals 3 servings of Vegetables
Date:
December 27, 2006 12:26 PM
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1440) HDL Booster - Boost your good cholesterol
Date:
March 16, 2006 12:51 PM
HDL BOOSTER
(Product No. 02922)
DESCRIPTION:
HDL Booster is a physician-developed dietary supplement that has been clinically shown to increase good cholesterol levels, particularly HDL-2, the best form of cholesterol.* The formula combines essential vitamins and minerals, at levels recommended by the American Heart Association (AHA), with key amino acids, powerful antioxidants, and traditional herbal extracts to provide superior support for cardiovascular health.*
HDL Booster:
· Formulated by Dr. Dennis Goodman, Chief of Cardiology at
· Clinically studied to increase good cholesterol levels up to 23%*1
· All-inclusive formula; includes ingredients recommended in accordance with the American Heart Association
· Replaces the CoQ10 depleted by cholesterol lowering (statin) drugs.*2
STRUCTURE/FUNCTION:
HDL Booster has been clinically shown to increase HDL cholesterol levels.* HDL Booster also supports healthy cholesterol and healthy triglyceride levels already within the normal ranges.* By reducing C-reactive protein levels, HDL Booster helps support the body’s natural anti-inflammatory response.*
FORMULA:
Two tablets (one serving) contain:
Vitamin C (ascorbic acid) 148 mg
Vitamin E (as natural mixed tocopherols) 35 IU
Niacin (as niacinamide) 21 mg
Vitamin B6 (as pyridoxine HCl) 3 mg
Folic Acid 301 mcg
Vitamin B12 (as cyanocobalamin) 20 mcg
Magnesium (from magnesium amino acid chelate) 10 mg
Selenium (as L-selenomethionine) 49 mcg
Proprietary Blend 388 mg
hawthorn (Crategus oxyacantha) berry extract,
taurine, garlic (Allium sativum) bulb, grape seed (Vitis
vinifera) extract, grape skin (Vitis vinifera) extract,
N-acetyl-L-cysteine, alpha-lipoic acid, soy (Glycine
max) isoflavones, tocotrienols
L-Arginine (as L-arginine HCl) 153 mg
L-Carnitine (as L-carnitine L-tartrate) 51 mg
Coenzyme Q10 (CoQ10)(ubiquinone 10) 25 mg
Policosanol 7 mg
Other ingredients: See label for most current information.
Contains no: sugar, salt, yeast, wheat, gluten, corn, dairy products, artificial coloring, artificial flavoring, or preservatives. This product contains natural ingredients; color variations are normal.
INTRODUCTION:
Cholesterol, the soft, waxy substance present among the lipids (fats) in the bloodstream and in all cells, is important for wide variety of physiological functions. It is essential for the formation of cellular membranes, necessary for the production of bile salts, and also plays a role in the synthesis of certain hormones.3-5
Cholesterol is both produced by the body and obtained from food. Endogenous cholesterol is formed by human cells, particularly liver cells, whereas exogenous cholesterol is absorbed through the gastrointestinal tract from food.3,4
Because cholesterol can not be metabolized for energy, it must be removed from the body once it has served its function. The major route of removal is through the liver, where it is processed and subsequently excreted from the body.3,4
Types of Cholesterol
Cholesterol is lipophilic (“fat loving” or water insoluble) by nature. It can not be dissolved in the blood, and must, therefore, be transported by carriers known as lipoproteins. These carriers are classified by density, with LDL (low density lipoproteins) and HDL (high density lipoproteins) being the most common.4,5
LDL is often referred to as “bad” cholesterol. LDLs carry cholesterol throughout the body. Conversely, HDL, or “good” cholesterol, is responsible for carrying cholesterol away from the arteries to the liver where it is eventually processed and eliminated from the body.3,4,6
Scientific studies have shown that both types of cholesterol are important indicators of cardiovascular health. But recent research, focusing on the beneficial subtypes of HDL, has found that certain fractions of HDL may be more supportive of cardiovascular health than others. The two most notably supportive HDL fractions are HDL-2 and HDL-3.7
The smaller HDL-3 is synthesized by the liver and intestines. This form, which is known as “free cholesterol-rich” HDL, scavenges or “scoops up” free cholesterol. The cholesterol is then chemically altered by the addition of an ester group. When sufficient cholesterol is esterified, HDL-3 becomes HDL-2, which is therefore referred to as “cholesterol ester-rich” HDL. HDL-2 is larger in size and has been shown to be more cardiosupportive than HDL-3.*7
HOW IT WORKS:
HDL is known to possess antioxidant activity and to help balance the body’s natural anti-inflammatory response, both of which are important for cardiovascular health, but its most important function is the role it plays in cholesterol transport.6,8 High levels of HDL cholesterol are also associated with reduced platelet activity, another key indicator of arterial and venous health.9
Both HDL and LDL levels are important indicators of healthy cardiovascular function.* Therefore, supplements that increase the level of good cholesterol can profoundly impact heart health.* In 2002, an open label pilot study was conducted at
The following chart summarizes the benefits of each of the ingredients in HDL Booster:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1238) Coenzyme Q10 and Cardiovascular Health.
Date:
December 13, 2005 11:34 AM
CoQ10 is a vitamin-like compound that is produced naturally in the human body and is also found in most living organisms. It is also called ubiquinone, a combination of quinone, a type of coenzyme, and ubiquitous, meaning it exists everywhere in the human body. CoQ10 plays an important role in your body’s energy production and is an essential component of the mitochondria, where it helps to metabolize fats and carbohydrates and maintain cell membrane flexibility. CoQ10 is also involved in the production of several key enzymes that are used to create ATP, which is burned by your body for energy, and used in the energy transfer between mitochondria and cells. Without CoQ10, you would not be able to function! CoQ10 is also an effective antioxidant that may beneficially affect the aging process. As we age, our body’s production of CoQ10 declines by as much as 80 percent. Because it is so important to energy production, and therefore life, researchers believe that this decline may be a factor in the effects of aging on the human body. Clinical trials on both animal and human subjects have revealed a marked decrease in CoQ10 levels in relation to a wide variety of diseases. As a free radical scavenger, CoQ10 inhibits lipid peroxidation – a normal aspect of the aging process that is implicated in certain agerelated diseases. Studies conducted in the last fifteen years suggest CoQ10 is important for maintaining healthy intracellular activity, and some researchers have compared its efficiency to that of vitamin E, one of the most effective of all dietary antioxidants. Research has shown that CoQ10, along with glutathione and selenium, works to regenerate or recycle vitamin E after it’s capacity to fight radicals has been diminished, thereby allowing vitamin E to remain active as an antioxidant for a longer period of time in your body. CoQ10 was first discovered by Dr. Frederick Crane of the University of Wisconsin in 1957. One year later, Professor Karl Folkers and others at Merck Inc. identified and recorded CoQ10’s chemical structure, and were the first to produce it through fermentation. Intermittent research led to its use in Japan for cardiac insufficiencies during the 1960’s. Dr. Folkers championed more intensive research into CoQ10’s role in cardiovascular health in 1972, after he and an Italian scientist, Gian Paolo Littarru, discovered that persons with cardiac insufficiencies had very low levels of CoQ10, and supplementation increased CoQ10 levels and positively affected heart health. Soon afterwards, the Japanese developed a method that allowed pure CoQ10 to be produced in quantities large enough for significant clinical trials. During the 1980’s this method was perfected in Japan, and medical technology finally allowed scientists to measure CoQ10 levels in blood and tissues, leading to a surge in further research. It was during this time that a Swedish researcher, Lars Ernster, drew attention to CoQ10’s role as a free radical-scavenging antioxidant. Today a multitude of research supports CoQ10’s health benefits. As a result of the overwhelmingly positive reports from studies conducted since CoQ10’s discovery, the Japanese were the first to approve widespread use of CoQ10, granting market approval for it in 1974. From 1974 to 1982, CoQ10 use in Japan grew rapidly until it was one of the most widely used products in the Japanese pharmaceutical industry. It is still widely used today, and has a long history of safe use. In “An Introduction To Coenzyme Q10” by Peter H. Langsjoen, M.D., F.A.C.C., he lists the substantial amount of scientific evidence that supports CoQ10’s benefits. “Internationally, there have been at least nine placebo controlled studies on the treatment of heart disease with CoQ10: two in Japan, two in the United States, two in Italy, two in Germany, and one in Sweden. All nine of these studies have confirmed the effectiveness of CoQ10 as well as it’s remarkable safety. There have now been eight international symposia on the biomedical and clinical aspects of CoQ10 (from 1976 through 1993). These eight symposia comprised over 3000 papers presented by approximately 200 different physicians and scientists from 18 countries.” “The majority of the clinical studies concerned the treatment of heart disease and were remarkably consistent in their conclusions: that treatment with CoQ10 significantly improved heart muscle function while producing no adverse effects or drug interactions.” There are many CoQ10 supplements on the market today, and it can be difficult to choose the best brand and dosage. CoQ10 is a fat-soluble substance, which means it is more easily absorbed and used by your body in the presence of fat. CoQ10 supplements that include lecithin or another dietary fat will be more effective, and CoQ10 in a softgel form should be in an oil base, usually soybean oil. The dosage most commonly used in research is 30 mg, but higher doses are optimal and may be required to maintain optimal levels as we age. Always remember to consult your health practitioner before taking dietary supplements if you have current health problems or are taking prescription medication. Now Foods continues to be a leading supplier of high-quality, low cost CoQ10 products. In 1999 and 2003 NOW Foods CoQ10 was voted the best-selling brand in health food stores nationwide, earning the Vity Award from Vitamin Retailer magazine. NOW carries eight different effective potencies of CoQ10, ranging from 30mg to 400mg, in lonzenges, softgels, and vegetable capsules. Many of our formulas are complexed with other synergistic nutrients like vitamin E, selenium, lecithin, and hawthorn for greater absorption and efficiency.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1012) Hypericin’s Photodynamic Ability
Date:
July 15, 2005 09:08 AM
Hypericin’s Photodynamic Ability One of hypericin’s qualities that enhances its ability to act therapeutically is that of being photodynamic; that is, its different qualities are either initiated by the presence of light or enhanced by it. Most of the contemporary studies dealing with hypericin have in some way or another dealt with how hypericin performs in its various functions when exposed to light. A 1995 study published in Photochemistry-Photobiology touts hypericin’s therapeutic actions in the viral and cancer worlds, especially when exposed to light. A 1994 Laryngyscope study suggested that hypericin has shown the ability to be an effective photosensitizer for certain forms of human cancer. And a 1994 Photochemistry-Photobiology study states that “the photocytocidal activity of this quinone on neoplastic cells is superior to that of antitumor anthraquinone drugs, such as daunomycin and mitoxanthrone . . .”4 The list goes on and on. The consensus seems to be that not only does hypericin possess various therapeutic properties, but that these properties are usually augmented by the presence of light.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=624) HERBS FOR SUMMER HEALTH
Date:
July 11, 2005 09:29 PM
HERBS FOR SUMMER HEALTH Just about everyone looks forward to the summer months when school is out and more time can be spent outside. Backpacking, hiking, camping, boating, and bike riding are just a few of the adventures available. It’s a time for connecting and becoming reacquainted with nature while exploring the out of doors. Family camping trips and backpacking through the wilderness can help us put our hectic lives in perspective and renew as well as refresh the body. Along with the adventures, a few bumps, bruises, bites and stings are expected. Before the summer holiday begins, prepare by having some herbal remedies on hand to help with minor accidents that may occur. Aloe vera Aloe is one of the best choices for the first aid kit. Commercial preparations can be taken along on trips. A leaf from the plant can be sealed in a zip lock bag and tucked in the first aid kit for short term use. The plant has numerous healing abilities and can be used on minor burns, rashes, bumps, scrapes and bruises. The aloe plant is very useful for many conditions. Modern research has proven many of the benefits of Aloe vera. It has been used effectively for treating radiation burns, skin disorders, wounds, sunburn and dermatitis, to name a few. Aloe vera can help clean, soothe and relieve pain on contact. It penetrates through all three layers of the skin rapidly to promote healing. There are many different types of aloe products. Some include: Aloe gel: This is the undiluted gooey substance that is found in the center of the leaves. Aloe concentrate: The concentrate is the gel when the water content has been removed. Aloe juice: The juice is a digestible version of the aloe plant made from the gel with at least 50 percent Aloe vera gel. Aloe latex (aloin): The latex is the bitter yellow liquid from the pericyclic tubules of the outer rind of the leaf. The main constituent of this is aloin.1 Aloe is known for its healing and soothing effect on burns, wounds, and rashes. It can help clean, soothe and relieve pain on contact. It is able to penetrate all three layers of the skin rapidly to promote healing. It contains salicylic acid and magnesium which work together to produce an aspirin like analgesic and anti-inflammatory effect. The transparent gel on the inner leaf is applied directly to areas of the skin to treat burns, wounds, skin irritations and frostbite. The gel can is commonly found in many first-aid creams. Research has found that aloe when applied externally can actually help speed healing and restore skin tissue.2 It also aids in healing when used externally in cases of wounds, frostbite and burns.3 The healing of burns may be due in part to the moisturizing effect of aloe. It is easily absorbed into the skin preventing the air from drying the damaged skin tissue.4 Aloe can help with many minor irritations that can occur during the summer months. Steven R. Schechter, N.D. conducted a study in 1967 at the Children’s Hospital in Cincinnati to determine the healing benefits of aloe. Research animals were being treated for laser burns. Dr. Schechter used several different preparations and consistently found the aloe vera gel to produce the most healing results. He found the gel to help with many skin disorders including burns, lesions and cancers. 5 As much as we try to avoid sun exposure, it is almost impossible to completely avoid getting a sunburn at some point in our lives. We may forget the sunscreen or stay out longer than expected. Excessive exposure to the sun can be detrimental to health. But, aloe vera may help to lessen the damaging effects of the sun. A sunburn can damage the skin as well as the immune system. Research by Dr. Faith Strickland of the Anderson Cancer Center at the University of Texas points to the possibility of aloe vera helping to eliminate the damage done to the immune system and skin. It may even help to restore the immune system to full function. Many individuals have found that having an aloe vera plant growing in the home, within easy access, is an easy and simple way to treat common injuries. Commercial p reparations are also available which contain aloe. Scientists have found the plant to contain antiseptic, antiviral, antibacterial, anesthetic and tissue healing properties. So why shouldn’t it be useful as a natural home remedy? Simply break off a leaf of the plant and slice down the middle of the leaf. Apply the thick inner gel to the injury whether it be a burn, insect bite, abrasion, scrape, rash, or other injury. The cut leaf can be placed directly on the wound and wrapped with gauze to secure it into place for a more serious injury. The skin will soak up of the gel as it soothes the affected area. Toxicity is rare, but some do have allergic reactions to Aloe vera products. The aloin, found in the bitter yellow latex, containing anthraquinones, may cause severe cramping and should be avoided by pregnant women and children. Aloe can also help with the following:
Endnotes
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=572) HAWAIIAN NONI (Morinda citrifolia)
Date:
July 11, 2005 08:50 PM
INTRODUCTION In a time when we are more concerned than ever with issues of health, a tried and true tropical herb called noni needs t o be added t o our list of the best natural remedies. It susage over hundreds of years supports it s description as a veritable panacea of therapeutic actions. At this writing, noni continues to accrue impressive medicinal credentials, and its emergence as an effective nat ural healing agent is a timely one. Amidst rising cancer rates, the high incidence of degenerative diseases like diabetes, and the evolution of ant ibiotic resist ant bacteria and new viral strains, herbs like noni are sought after for their natural pharmaceutical properties. Unquest ionably, all of us want to know how to:
Genus Rubiaceae Common Names Indian Mulberry (India), Noni (Hawaii), Nono (Tahiti and Raratonga), Polynesian Bush Fruit, Painkiller Tree (Caribbean islands), Lada (Guam), Mengkudo (Malaysia), Nhau (Southeast Asia), Grand Morinda (Vietnam), Cheesefruit (Australia), Kura (Fiji), Bumbo (Africa) Note: This is only a small sampling of vernacular names for Morinda citrifolia. Almost every island nation of the South Pacific and Caribbean has a term for this particular plant . This booklet will refer to the herb mainly as “ noni” or M. citrifolia, and is referring primarily to Hawaiin noni. Parts Used The parts of the noni plant most used for their medicinal and nutritional purposes are the fruit, seeds, bark, leaves, and flowers. Virtually every part of the noni plant is utilized for its individual medicinal properties; however, it is the fruit portion that is regarded as its most valuable. The seeds have a purgative action, the leaves are used to treat external inflammations and relieve pain, the bark has strong astringent properties and can treat malaria, the root extracts lower blood pressure, the flower essences relieve eye inflammations and the f ruit has a number of medicinal actions. Physical Description Morinda citrifolia is technically an evergreen shrub or bush, which can grow to heights of fifteen to twenty feet . It has rigid, coarse branches which bear dark, oval, glossy leaves. Small white fragrant flowers bloom out of cluster-like pods which bear creamy-white colored fruit. The fruit is fleshy and gel-like when ripened, resembling a small breadf ruit . The flesh of the fruit is characterist ically bitter, and when completely ripe produces a rancid and very dist inctive odor. Noni has buoyant seeds that can float formont hs in ocean bodies. The wood of the inflammatory, astringent, emollient, emmenagogue, laxative, sedative, hypotensive (lowers blood pressure) , blood purif ier, and tonic. Chemical Constituents Noni has various chemical constituents. First, it has an impressive array of terpene compounds, three of which—L. Asperuloside, aucubin, and glucose— have been identified by their actyl derivatives. Both caproic and caprylic acids have been isolated.1 Second, bushfruits, a category of which noni fruit is a member, are also considered a good source of vit - amin C.2 Third, Hawaiin noni has been linked to the synthesis of xeronine in the body which has significant and widespread health implications. Last , the alkaloid cont ent of the noni fruit is thought to be responsible for its therapeutic actions. Alkaloids exhibit a wide range of pharmacological and biological act ivitiesin the human body. They are nitrogencontaining organic compounds which can react with acids to form salts and which are the basis of many medicines. The following is an in-depth chemical analysis of each plant part and it s chemical constituents.
FLOWER
FRUIT
discovered an alkaloid in the Hawaiin noni fruit which he calls proxeronine and which he believes has appreciable physiological actions by acting as a precursor to xeronine, a very crucial compound (see later sections) . In addition, a compound found in the fruit called damnacanthol is believed to help inhibit cert ain viruses and cellular mutations involved in cancer. ROOT AND ROOT BARK
Pharmacology Recent surveys have suggested that noni fruit exerts antibiotic action. In fact, a variety of compounds which have antibacterial properties (such as aucubin) have been identified in the fruit.5 The 6-Dglucopyranose pentaacet ate of the fruit extract is not considered bacteriostatic.6 Constituents found in the fruit portion have exhibited ant imicrobial action against Escherichia coli, Salmonella typhi (and other types) , Shigella paradysenteriae, and Staphylococcus aureaus. Compounds found in the root have the ability to reduce swollen mucous membrane and lower blood pressure in animal studies. Proxeronine is an alkaloid constituent found in Hawaiin noni fruit which may prompt the production of xeronine in the body. It is considered a xeronine precursor and was discovered in noni fruit by Dr. Ralph M. Heinicke. He has theorized that this proenzyme can be effective in initiating a series of beneficial cellular reactions through its involvement with the integrity of specific proteins. He points out that tissues contain cells which possess certain recept or sites for xeronine. Because the reactions that can occur are so varied, many different therapeutic actions can result when xeronine production escalates, explaining why Hawaiin noni is good for so many seemingly unrelated disorders. Damnacanthol is another compound contained in the fruit of the Hawaiin noni plant which has shown the ability to block or inhibit the cellular function of RAS cells, considered pre-cancerous cells. Body Systems Targeted The following body systems have all been effec-freeze-dried capsules, dehydrated powder or fruit, and oil. Noni plant constituents are sometimes offered in combination with other herbs. Some products contain a percent age of the fruit, bark, root and seeds for their individual therapeutic properties. Satety Extracts of M. citrifolia are considered safe if used as directed; however, pregnant or nursing mothers should consult their physicians before taking any supplement . High doses of root extracts may cause constipation. Taking noni supplements with coffee, alcohol or nicotine is not recommended. Suggested Uses Ideally, noni extracts should be taken on an empty stomach prior to meals. The process of digesting food can interfere with the medicinal value of the alkaloid compounds found in Hawaiin noni, especially in its fruit . Apparently, stomach acids and enzymes destroy the specific enzyme which frees up the xeronine compound. Take noni supplements without food, coffee, nicotine or alcohol. Using supplements that have been made from the semi-ripe or light - green fruit is also considered preferable to the ripe, whit ish fruit . NONI: ITS USE AND HISTORY Noni is a tropical wandering plant indigenous to areas of Australia, Malaysia and Polynesia. It is considered native to Southeast Asia although it grows from India to the eastern region of Polynesia. Morinda citrifolia has a long history of medicinal use throughout these areas. It is thought to be the “most widely and commonly used medicinal plant prior to the European era.” 7 Centuries ago, the bushfruit was introduced to native Hawaiians, who subsequently called it “noni” and considered its fruit and root as prized medicinal agents. Among all Polynesian botanical agents of the 19th and 20th centuries, Hawaiin noni has the widest array of medical applications. Samoan and Hawaiian medical practitioners used noni for bowel disorders (especially infant diarrhea, constipation, or intestinal parasites) , indigestion, skin inflammation, infection, mouth sores, fever, contusions and sprains. Hawaiians commonly prepared noni tonics designed to treat diabetes, stings, burns and fish poisoning.8 The herb’s remarkable ability to purge the intestinal tract and promote colon health was well known among older Hawaiian and Tahitian natives and folk healers. Interestingly, field observations regarding its repu-remarkable healing agent . Wonder Herb of Island Folk Healers Common to t he thickets and forests of Malaysia and Polynesia, and the low hilly regions of the Philippine islands, noni has been cultivated throughout communities in the South Pacific for hundreds of years. Its Hawaiian use is thought to originate from inter-island canoe travel and settlement dating to before Christ . Its hardy seeds have the ability to float which has also contributed to its distribution among various seacoasts in the South Pacific region. Historical investigation has established the fact that some of Hawaii’s earliest settlers probably came viaTahiti. For this reason, Tahitian herbal practices have specific bearing on the herbal therapeutics of islands to the nort h. The very obvious similarities between the Hawaiian vernacular for herbal plants like noni and Tahitian names strongly suggests the theory of Polynesian migrations to Hawaii. Cultures native to these regions favored using Morinda citrifolia for treating major diseases and ut ilized it as a source of nourishment in times of famine.9 Noni fruit has been recognized for centuries as an excellent source of nutrition. The peoples of Fiji, Samoa and Rarat onga use the fruit in both its raw and cooked forms.10 Traditionally, the fruit was propicked before it was fully ripe and placed in the sunlight . After being allowed to ripen, it was typically mashed and its juice extracted through a cloth. Noni leaves provided a veget able dish and their resiliency made them desirable as a fish wrap for cooking. Noni’s Medical Reputation Elaborate traditionalrituals and praying rites usually accompanied the administration of noni. Int erestingly, cultures indigenous to the Polynesian islands had a significant understanding of their flora. For example, native Hawaiians maint ained a folkmedicine taxonomy t hat was considered second to none.11 Noni was not only used for medicinal purposes but for its food value, for clot hing and for cloth dyes as well. Research indicates that noni was among the few herbal remedies that islanders considered “ tried and true.” In Hawaii, trained herbal practitioners reserved the right to prescribe plant therapies.12 Records indicate that Hawaiian medical practices were based on extensive and very meticulous descriptions of symptoms and their prescribed herbal treatments. Dosages were controlled and the collection and administration of plant extracts was carefully monitored.13 In addition to Morinda, it was not uncommon for these herbal doctors to also recommend using In regard to its application for common ailments, Hawaiians and other island communities traditionally prescribed noni to purge the bowel, reduce fever, cure respiratory infections such as asthma, ease skin inflammations, and heal bruises and sprains. In other words, noni was widely used and highly regarded as a botanical medicine. A Timely Reemer gence Today, the natural pharmaceutical actions of the chemical constituents contained in noni are scientif-ically emerging as valuable bot anical medicines. Tahitian “nono” intrigued medical practitioners decades ago; however, due to the eventual emergence of synthetic drugs, interest in this island botanical diminished until recent years. Ethnobot anists are once again rediscovering why Hawaiian people havet reasured and cultivat ed Morinda citrifolia for generations. Noni is now finding its way into western therapeutics and is referred to as “ the queen” of the genus Rubiaceae. Its ability to reduce joint inflammation and target the immune system have made it the focus of the modern scientific inquiry. Dr. Ralph Heinicke has conducted some fascinating studies on the chemical constituents of the Hawaiin noni fruit. His research centers on the proxeronine content of the fruit juice and how it profoundly influences human physiology. In addition, scientific studies investigating noni as an anti-cancer agent have been encouraging. It s conspicuous attributes and varied uses have elevat edits status to one of the best of the healing herbs. Today Morinda citrifolia is available in liquid, juice, freezedried capsules, or oil forms, and is considered one of nature’s most precious botanicals. TRADITIONAL USES OF NONI Throughout tropical regions, virtually every part of Morinda citrifolia was used to treat disease or injury. Its curative properties were well known and commonly employed. PatoaTama Benioni, a member of the Maoritribe from the Cook Islands and a lecturer on island plants explains: Traditionally Polynesians use noni for basically everything in the treatment of illness. Noni is a part of our lives. Any Polynesian boy will tell you he’s had exper ience with it . We use juice from its roots, its flowers, and its fruit... my grandmother taught me to use noni from the roots and the leaves to make medicine for external as well as internal use, and for all kinds of ailments, such as coughs, boils, diseases of the skin, and cuts.15 decoctions to stimulate delayed menst ruation.
XERONINE: THE SECRET OF NONI? One informed professional on the subject of noni is Dr. Ralph Heinicke, a biochemist who has researched the active compounds of noni fruit for a number of years. He discovered that the Hawaiin noni fruit contains an alkaloid precursor to a very vital compound called xeronine. Wit hout xeronine, life would cease. In Dr. Heinicke’s view, noni fruit provides a safe and effective way to increase xeronine levels, which exert a crucial influence on cell health and protction. His research suggests that the juice from the M. citrifolia fruit contains what could technically be considered a precursor of xeronine—proxeronine. This compound initiates the release of xeronine in the intestinal tract after it comes in contact with a specific enzyme which is also contained in the fruit . Because proteins and enzymes have so many varied roles within cell processes, the normalization of these proteins with noni supplemenation could initiate avery wide variety of body responses and treat many disease condit ions. Proteins are the most important catalysts found in the body. The beauty of obtaining a precursor to xeronine from the noni fruit is that the body naturally decides how much of this precursor to convert to xeronine. Disease, stress, anger, trauma and injury can lower xeronine levels in the body, thus creat ing a xeronine deficit . Supplementing the body with noni fruit is considered an excellent way to safely and naturally raise xeronine levels. It is the research and theories of Dr. Heinicke which have made the juice of the Hawaiin noni fruit a viable medicinal substance. He writes: Xeronine is analkaloid, a substance the body produces in order to activate enzymes so they can function properly. It also energizes and regulates the body. This par-ticular alkaloid has never been found because the body makes it, immediately uses it, and then breaks it down. At no time is there an appreciable, isolable amount in the blood. But xeronine is so basic to the functioning of proteins, we would die without it . Its absence can cause many kinds of illness.17 Because so many diseases result from an enzyme malfunction, Dr. Heinicke believes that using the noni fruit can result in an impressive array of curative applications. Interestingly, he believes that we manufacture proxeronine while we are sleeping. He proposes t hat if we could constantly supply our bodies wit h proxeronine from other sources, our need to sleep would diminish.18 NONI PROCESSING How an herb is processed is crucial to how beneficial it is: this is especially true of noni, with its unique enzymes and alkaloids. Morinda citrifolia should be picked when the fruit is turning from its dark green immature color to its lighter green color, and certainly before it ripens to its white, almost translucent color. Once picked, noni, like aloe, will denature extremely quickly due to its very active enzymes. After harvesting, it should swiftly be flash frozen. This is similar to what is done to fish caught at sea to keep them f esh. This stops it from losing its potency while not damaging any of its constituents. To process noni, freeze-drying is recommended. This removes only the water without damaging any of this miracle plant’s vital enzymes and other phytonutrients like xeronine and proxeronine. This pure high-quality noni fruit juice powder is then encapsu-has a very harsh taste and an extremely foul smell, similar to the fruit it self . Other methods of processing include thermal processing, dehydrat ion and air drying. Thermal processing is generally found in liquids, while the dehydrat ed noni is then milled and encapsulated. Unfortunately both methods utilize high heat (110+°F) , which can deactivate many of the vital compounds that make noni so import ant . Air-drying is effect ive without using damaging heat but has serious quality control problems for commercial production. MODERN APPLICATIONS OF NONI Overview Noni possesses a wide variety of medicinal properties which originat e from its differing plant component s. The fruit and leaves of the shrub exert antibacterial activities. Its roots promote the expulsion of mucus and the shrinkage of swollen membranes making it an ideal therapeutic for nasal congest ion, lung infect ions, and hemorrhoids. Noni root compounds have also shown natural sedative properties as well as the ability to lower blood pressure. Leaf extracts are able to inhibit excessive blood flow or to inhibit the formation of blood clots. Noni is particularly useful for its ability to treat painful joint conditions and to resolve skin inflammations. Many people drink noni fruit extracts in juice form for hypert ension, painful menstruation, arthritis, gastric ulcers, diabetes, and depression. Recent studies suggest that its anticancer activit y should also be considered. Concerning the therapeutic potential of the Hawaiin noni fruit, Dr. Heinicke writes: I have seen the compound found in noni work wonders. When I was still investigating its possibilities, I had a friend who was a medical research scientist administer the proxeronine to a woman who had been comatose for three months. Two hour safter receiving the compound, she sat up in bed and asked where she was. . . . Noni is probably the best source of proxeronine that we have today.19 Studies and surveys combined support the ability of noni to act as an immunost imulant, inhibit the growth of certain tumors, enhance and normalize cellular function and boost tissue regeneration. It is considered a powerful blood purifier and contributor to overall homeostasis. xeronine, which appears to be able to regulate the shape and integrity of cert in proteins that individually contribute to specific cellular activities. Interestingly, this effect seems to occur after ingestion, inferring that the most active compound of noni may not be present in uneaten forms of the fruit or other plant parts. Some practitioners believe that xeronine is best obtained from a noni fruit juice precursor compound. The enzymatic reactions that occur with taking the juice on an empty stomach are what Dr. Heinicke believes set cellular repair intomotion. Cancer A study conducted in 1994 cited the anticancer activity of Morinda citrifolia against lung cancer. A team of scientists from the University of Hawaii used live laboratory mice to test the medicinal properties of the fruit against Lewis lung carcinomas which were artificially transferred to lung tissue. The mice that were left untreated died in nine to twelve days. However, giving noni juice in consistent daily doses significantly prolonged their life span. Almost half of these mice lived for more than fifty days.20 Research conclusions state that the chemical constituents of the juice acted indirectly by enhancing the ability of the immune system to deal with the invading malig-nancy by boosting macrophage or lymphocyte activit y. Furt her evaluation theorizes that the unique chemical constituents of Morinda citrifolia initiate enhanced T-cell activity, a reaction that may explain noni’s ability to treat a variety of infectious diseases. 21 In Japan, similar studies on tropical plant extracts found that damnacanthol, a compound found in Morinda citrifolia, is able to inhibit the function of KRAS- NRK cells, which are considered precursors to certain types of malignancies.22 The experiment involved adding noni plant extract to RAS cells and incubating them for a number of days. Observation disclosed that noni was able to significantly inhibit RAS cellular function. Among 500 plant extracts, Morinda citrifolia was determined to contain the most effective compounds against RAS cells. Its damnacanthol content was clinically described in 1993 as “a new inhibit or of RAS function.” 2 3 The xeronine fact or is also involved in that xeronine helps to normalize the way malignant cells behave. While they are still technically cancer cells, they no longer function as cells with unchecked growth. In time, the body’s immune system may be able to eradicate these cells. Arthritis with arthritic disease. One link to arthritic pain may be the inability to properly or completely digest proteins which can then form crystal-like deposits in the joints. The ability of noni fruit to enhance protein digestion through enhanced enzymatic function may help to eliminate this particular phenomenon. In addition, the alkaloid compounds and plant met abolites of noni may be linked to its apparent anti-inflammatory action. Plant sterols can assist in inhibiting the inflammatory response which causes swelling and pain. In addition, the antioxidant effect of noni may help to decrease free radical damage in joint cells, which can exacerbate discomfort and degeneration. Immune System The alkaloid and other chemical compounds found in noni have proven themselves to effectively control or kill over six types of infectious bacterial strains including: Escherichia coli, salmonellatyphi (and other types) , shigella paradysenteriae, and staphylo - coccus aureaus.25 In addition, damnacanthol, was able to inhibitt he early antigen stage of the Epstein- Barr virus. The bioactive components of the whole plant, combined or in separate portions, have demonst rat - ed the ability to inhibit several different strains of bacteria. Anecdotal reports support this action in that noni seems particularly effective in shortening the duration of certain types of infection. This may explain why noni is commonly used to treat colds and flu. The chemical constituents found in noni and the possibility that they stimulate xeronine production— as well as initiate alkaloid therapy—may explain noni’s reputation for having immuno-stimulatory properties. Alkaloids have been able to boost phagocytosis which is the process in which certain white blood cells called macrophages attack and literally digest infectious organisms. Interestingly, the ant it umoraction of noni has been ascribed to an immune system response which involves stimulating T-cells. tropical regions during World War II learned of the fruit’s ability to boost endurance and stamina. Native cultures in Samoa, Tahiti, Raratonga and Australia used the fruit in cooked and raw forms. M. citrifolia is considered a tonic and is especially recommended for debilitated conditions. Antioxidant The process of aging bombards the body with free radicals which can cause all kinds of degenerative diseases. The xeronine theory promoted by Dr. Heinicke submit s t hat as our bodies age, we lose our ability to synthesize xeronine. To make matters worse, the presence of many environment altoxins actually blocks the production of xeronine as well. He believes that the proxeronine content of Hawaiin noni fruit juice can help to block these actions, thereby working as an antiaging compound.26 The phytonutrients found in noni assist in promot - ing cell nourishment and prot ect ion from free radicals created by exposure to pollution and other potentially damaging agents. In addition, Morinda citrifolia contains selenium, which is considered one of the best antioxidant compounds available. Diabetes While scientific studies are lacking in this particular application of noni, Hawaiians used various parts of the plant and its fruit to treat blood sugar disorders. Anecdotal surveys have found t hat noni is current ly recommended for anyone with diabetes. Pain Killer A 1990 study found that extracts derived from the Morinda citrifolia root have the ability to kill pain in animal experiments.27 Interest ingly, it was during this study that the natural sedative action of the root was also noted. This study involved a French team of scientists who noted a significant central analgesic activity in laboratory mice.28 Dr. Heinicke has stated, “Xeronine also acts as a pain reliever. A man wit h very advanced int est inal cancer was given three months to live. He began taking the proxeronine and lived for a whole year, pain-free.” 29 Skin Healing Agent One of the most prevalent hist rical uses of noni was in poultice form for cuts, wounds, abrasions, burns and bruises. Using its fruit extract for very serious burns has resulted in some extraordinary healing. Because skin is comprised of protein, it immediately responds to the presence of xeronine. burn site throught he direct application of a noni poultice is considered quite effective by Dr. Heinicke and his colleagues, who have studied enzymatic therapy. Concerning burns, he has written: I believe that each tissue has cells which contain proteins which have receptor sites for the absorption of xeronine. Certain of these proteins are the inert for ms of enzymes which require absorbed xeronine to become active. This xeronine, by converting the body’s procol- langenase system into a specific protease, quickly and safely removes the dead tissue from burns.30 Drug Addiction The xeronine link to treat ing drug addiction is based on the notion that flooding t he brain with extra xeronine can reverse the neurochemical basis for addiction. This natural alkaloid is thought to normalize brain receptors which subsequent ly results in the cessation of physiological dependence on a certain chemical like nicotine.3 1 The potential of Hawaiin noni as a natural stimulat or for t he production of xeronine may have profound implications in treating various types of addictions. Complementary Agents of Noni
PrimaryApplications of Noni
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=570) Pep Up and Go!
Date:
June 14, 2005 05:45 PM
Pep Up and Go! by Harris Parker Energy Times, February 2, 2000 Feel your energy flagging? You've lost count of the number of phone calls you fielded all afternoon-the last was from your son, who missed the late bus home from school-and colleagues needing your decision are lined up outside your office. Your husband has invited clients home for dinner. You wilt like a new hairdo on a damp August day and pray for a miracle to jump-start your engine. Your pep quotient depends on three essential ingredients: nutrients you consume through your diet and supplements, how much you exercise and your sleep schedule.(Of course, if you're troubled by any kind of disabling, ceaseless fatigue accompanied by mental fuzziness, joint pain, sore throat, swollen glands, headaches and other chronic distress, consult your health practitioner.) Vitamins and Energy Certain nutrients are called vitamins because scientists consider them to be crucial for vitality. They generally function as coenzymes, partnering with the enzymes that are catalysts for the chemical reactions constantly taking place in our bodies. Our need to replenish our store of vitamins, which may merge with cell, muscle, enzyme, hormone, blood and bone structure once they have been absorbed, depends on their rate of utilization, according to The Real Vitamin & Mineral Book (Avery) by Shari Lieberman, PhD, and Nancy Bruning. While a low-fat diet rich in raw fruits and vegetables helps supply important nutrients, a B complex supplement and a balanced multivitamin can guarantee daily vitamin levels. Be Energetic with B Vitamins Vitamins, especially the B vitamins, play extremely important roles in producing cellular energy. The chart on page 39 lists the key vitamins and describes their effects as well as the consequences of not getting enough of them. Their benefit is felt most profoundly in the energy producing process known as the Krebs cycle (which we'll explain in a moment). Vitamins B2 and B3, for example, supply the major building blocks for substances that are called flavin adenine dinucleotide (FAD and FADH) and nicotinamide adenine dinucleotide (NAD and NADH), which are critical elements of energy production in the Krebs cycle as well as a process called oxidative phosphorylation. Hundreds of Reactions Even though you may never have heard of NAD and NADH, these molecules are found in very many places throughout your body; they play a role in hundreds of biochemical reactions in all kinds of cells. B vitamins also combine with other materials to build coenzymes, chemicals which help form other chemicals necessary for cellular energy. B vitamins are crucial: miss out on one or more and you may break these metabolic chains necessary for peak energy. Energy to Spend The main energy currency of every cell single cell is ATP: a chemical called adenosine triphosphate. This material is used by cells for every imaginable task including reproduction, growth, movement and metabolism. Specialized metabolic cycles within the cell are designed to generate ATP. Consequently, the more ATP our cells create, the more energy can be generated. The raw materials used to make cellular energy are glucose (blood sugar) and "free" fatty acids. The best way to supply your cells with the sugar they need is to consume complex carbohydrates which also supply fiber and other nutrients. When you eat carbohydrates, they are made into glucose which is stored as a starch called glycogen in muscles and the liver. Your body can rapidly turn glycogen into glucose for extra energy. (The process of making energy from glycogen yields carbon dioxide and water as well as ATP.) Making Energy The first step in making glucose into energy is called glycolysis. This complicated process requires nine different steps. During these steps, glucose is made into a substance called pyruvate. The process of glycolysis requires ATP, but yields twice as much ATP as is present when it starts. From here, the process gets a little more complicated as pyruvate enters into a complex chain of events in tiny cellular structures called mitochondria. (Many metabolic events take place in the mitochondria.) The pyruvate molecules are converted to a molecule known as acetyl coenzyme A and eventually made into carbon dioxide, water and more ATP. This process is known as the Krebs cycle or citric acid cycle. It also involves a series of events known as oxidative phosphorylation in which NADH formed during the Krebs cycle is oxidized to form ATP. Why is fat such a concentrated source of energy? Free fatty acids enter the Krebs cycle to help generate ATP much more efficiently than glucose - producing roughly six times more energy per gram than glucose. And Don't Overlook. . . . . .other supplements that may aid energy production: • Alpha Lipoic Acid, an antioxidant that works in the fatty tissues of cell membranes and in cells' watery interiors • Coenzyme Q10, also known as ubiquinone as it exists everywhere in the body, acts like a vitamin because it stimulates some reactions. CoQ10 protects cell membranes, especially of the heart, against oxidation and toxins. Ginsengs: Energy Generators With their legendary and slightly mysterious characteristics, the ginsengs are greatly respected natural energy boosters. " Perhaps no herb has excited so much interest in medical circles as ginseng, and yet, strangely, it does not actually 'cure' any one particular ailment," reports Michael Hallowell, the author of Herbal Healing (Avery) and a frequent lecturer on botanic medicine. "Rather, its virtue lies in its tremendous power as a tonic and invigorator. Russian athletes are prescribed large amounts of ginseng because researchers in Moscow have shown that it not only improves stamina, but also increases the efficiency with which blood is pumped to the muscles." What are the physiological mechanisms that allow ginseng to bolster your get up and go? In order to unravel the legend and lore of ginseng, the first step is understanding the intricacies of the three types: • Asian (Panax ginseng), which produces the strongest and most profound stimulation; • American (Panax quinquefolium), which soothes at a more subtle level; • Siberian (Eleutherococcus senticosus), a stamina booster embraced by a wide range of athletes. All three varieties are treasured for their ability to help people adjust to stress. Biologically Active The ginsengs are adaptogens, "biologically active substances found in certain herbs and plants that help the body and mind adapt to the changes and stress of life," says Stephen Fulder, MD, author of The Book of Ginseng and Other Chinese Herbs for Vitality (Inner Traditions). "Stress is not an illness in itself. Stress is change, our ability to adapt to all the changes that occur in life, emotional or physical, from exercise, work, chemicals, drugs, food, radiation, bacteria, disease, temperature, or simply too many late nights or too much fun." The body reacts to stress by producing the hormone adrenaline, which throws the whole body into a state of alert. Metabolism, blood pressure and circulation accelerate; immunity and resistance drastically decline; performance suffers. Top-Notch Tonics Enter the ginsengs, with their varied, subtle tonic qualities. The Greek name for this herb, "panax," means "panacea" or cure-all. But the Chinese, who first referred to it 2,000 years ago, more literally called it "ren shen" or "person root," in reference to its physical resemblance to a miniature human form. " Most exhibit medicinal properties, but each species has a different chemical makeup and has a unique application in Traditional Chinese Medicine (TCM)," says Kim Derek Pritts, author of Ginseng: How to Find, Grow and Use America's Forest Gold (Stackpole). "In general, all true ginseng contains biologically active saponins (chemicals similar to human hormones), essential oils, carbohydrates, sugars, organic acids, nitrogenous substances, amino acids, peptides, vitamins and minerals." Building Vital Energy All the ginsengs strengthen, nourish and build Qi, the TCM concept describing basic vital energy circulating through our bodies. Every physical and mental function, from breathing, thinking, nutrition and circulation, is regulated by Qi. Although many of the Native American tribes used the abundant, indigenous Panax quinquefolium ginseng extensively, particularly to increase mental acuity and boost fertility, the herb never has been as popular in North America as it is in Asia. American ginseng traditionally has been a lucrative export crop to China, where the wild native variety suffers from overharvesting. Even today, according to Paul Bergner in The Healing Power of Ginseng & the Tonic Herbs (Prima), 95% of the American ginseng crop is exported to China, where XiYang Shen, or "western sea root," as it is called, is immensely valued and costs double what it does here. Energy Boost Jacques MoraMarco, author of The Complete Ginseng Handbook: A Practical Guide for Energy, Health and Longevity (Contemporary), as well as a licensed acupuncturist and doctor of Eastern medicine, suggests American ginseng for a slight energy boost. The moderate effect of American ginseng is considered a more appropriate tonic to the intensity of our pace and diet. Variations on a Theme In TCM terms, American ginseng cools and moistens, as well as lubricates and strengthens the body. It is reputed to reduce fevers and night sweats and alleviate hot, dry lung problems like smoker's cough. With its emollient qualities, American ginseng is considered to treat dry, wrinkled skin effectively. The Bolder Energizer Asian ginseng, which includes red Korean panax, is a bolder energizer taken by those who feel depleted from anemia, blood loss, cardiovascular weakness, injury, shock or trauma, as well as the disabling effects of age. In general, Asian ginseng is warming and stimulating, urging the body to run faster. Siberian ginseng, though botanically not a true ginseng, still acts similarly to Asian ginseng in its reputed power to control stress, boost energy, support the immune system, enhance performance and increase longevity. Called Wu Cha Seng in Chinese, Siberian ginseng is perceived by natural practitioners as an ideal herb for the healthy who want to lift both stamina and endurance. Experts believe it counteracts the effects of cortisol, the stress hormone produced by the adrenal glands in response to injury, pain or emotional turmoil. Natural Energy Boosters The herbal pharmacopeia includes several other natural energy boosters available in various forms-shakes and bars for those on the run-loaded with nutrition absent from commercial snacks. Some choices: • Ginkgo biloba-used in Chinese medicine to heat the body and increase sexual energy. Ginkgo enthusiasts take this herb to increase the supply of oxygen to the brain and generally increase circulation. • Gotu kola-may stimulate the central nervous system and help eliminate excess fluid, thereby reducing fatigue. • Astragalus-a Chinese herb that enhances energy and builds the immune system. It is credited with strengthening digestion, improving metabolism, increasing appetite, combating diarrhea and healing sores. • Schisandra-also a Chinese herb, treats respiratory illness, insomnia and irritability and rejuvenates sexual energy. Its mild adaptogens help the body to handle stress. • Licorice-is a favored endocrine toner in Chinese medicine. It is reputed to support the adrenals, the pair of small glands directly above the kidneys that secrete steroidal hormones, norepinephrine and epinephrine, the "fight or flight" hormones. People with high blood pressure or edema, or pregnant women, should avoid it. • Ashwagandha-an Ayurvedic herb used for thousands of years in the traditional healing of India as a potent strength builder for men and women. Experienced herbal practitioners acquire an impressive and fascinating store of knowledge and experience-you'll find it helpful to visit one as you begin your course of ginseng or other energy-boosting herbs. TCM Visitation When you visit a TCM practitioner, you'll notice that she evaluates your body's condition through an extremely careful examination of all the different systems: Several pulse points are felt in order to ferret out and detect troubling abnormalities. The condition and color of the tongue is observed to decipher digestive disorders. In addition, your urine may be examined to determine other imbalances and specific health problems. In many cases, your TCM practitioner will recommend ginseng as an adaptogen that can give you an overall boost. When taking ginseng, follow the directions on the package. Note: in some cases, you may want to consume a little bit less if you suffer headaches, insomnia or high blood pressure. Consult your health practitioner if you are afflicted with either acute inflammatory disease or bronchitis. Then take comfort in the eternal soothing wisdom of Chinese Traditional Medicine. In the first century A.D., the Shen Nong Ben Cao Jing (The Divine Husbandman's Classic of the Materia Medica) effusively described ginseng and the tonic herbs in this beguiling and intriguing manner: "The first class of drugs...are considered to perform the work of sovereigns. They support human life and they resemble heaven. They are not poisonous regardless of the quality and duration of administration."
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=353) Heart Science - A Five-Tiered Approach to Heart Health ...
Date:
June 02, 2005 12:07 PM
Your heart is crucial to every function of your body. It is the sole organ which pumps oxygen-rich blood through the entire circulatory system, feeding your cells and making life possible. Only recently are Americans realizing the importance of a proper low-fat diet, regular exercise, giving up cigarette smoking, and cutting down alcohol consumption to maintaining a healthy heart. Unfortunately, there has been a huge gap in the number of nutritional supplements which provide nutrients and herbs to support normal heart function. That’s where Source Naturals HEART SCIENCE comes in. Two years in the making, and backed by numerous scientific studies, the nutrients in HEART SCIENCE are some of the most soundly researched of all. Combining high potencies of these super-nutrients, HEART SCIENCE is the most comprehensive, cutting edge nutritional approach to proper heart care available. Source Naturals HEART SCIENCE— The Five Tiered Approach to Heart Health
Your heart never rests. Even while you sleep, your heart must keep working, relying on the constant generation of energy by the body for its very survival. If this vital organ stops beating for even a short amount of time, all bodily functions cease and life ends. Source Naturals HEART SCIENCE helps support heart function on the chemical, cellular, structural, and energetic levels. This broad spectrum formula includes ingredients specifically geared for Energy Generators for An Energetic Organ Every day, the human heart beats about 104,000 times, pumping over 8,000 liters of blood through the body! Because it requires so much energy to perform efficiently, the experts at Source Naturals included specialty nutrients in HEART SCIENCE such as Coenzyme Q10 and L-Carnitine — integral factors in the body’s energy production cycles — to enhance the body’s energy supply. There are three main interconnected energy generating cycles in our cells — the Glycolytic (sugar-burning) cycle, the Krebs’ (citric acid) cycle, and the Electron Transport Chain. Together they supply about 90 to 95% of our body’s entire energy supply, using fats, sugars, and amino acids as fuel. Coenzyme Q10 is one of the non-vitamin nutrients needed to maximally convert food into ATP (the energy producing molecule). It is the vital connecting link for three of the four main enzyme complexes in the Electron Transport Chain, the next step in energy generation after the Krebs’ cycle. Using the raw materials generated by the Krebs’ cycle, the Electron Transport Chain produces most of the body’s total energy! The heart is one of the bodily organs which contains the highest levels of CoQ10, precisely because it needs so much energy to function efficiently. CoQ10 is one of the most promising nutrients for the heart under investigation today. It has been postulated that as a result of its participation in energy production, CoQ10 improves heart muscle metabolism and the electrical functioning of the heart by enhancing its pumping capacity.8 Many factors such as a high fat diet, lack of exercise, and cigarette smoking can lead to suboptimal functioning of the heart, and therefore failure of the heart to maintain adequate circulation of blood. Interestingly, people whose lifestyles reflect the above factors also tend to have depleted levels of CoQ10 in the heart muscle.10 Researchers suggest taking between 10-100 mg per day of CoQ10;18,29 HEART SCIENCE provides an impressive 60 mg of CoQ10 per 6 tablets. Similar to CoQ10, L-Carnitine is important for energy production in heart cells. It is a natural amino acid-like substance which plays a key role in transporting fatty acids, the heart’s main source of energy, to the mitochondria, the “power plants” of each cell, where they are utilized for the production of ATP. Heart and skeletal muscles are particularly vulnerable to L-Carnitine deficiency. Studies have shown that supplementation with LCarnitine improves exercise tolerance in individuals with suboptimal heart and circulatory function, and seems to lower blood lipid status and increase HDL (good) cholesterol.16, 22 Each daily dose of HEART SCIENCE contains 500 mg of this extremely important compound. Like CoQ10 and L-Carnitine, B Vitamins help improve the ability of the heart muscle to function optimally. Each B Vitamin, after being converted to its active coenzyme form, acts as a catalytic “spark plug” for the body’s production of energy. Vitamin B-1, for example, is converted to Cocarboxylase, which serves as a critical link between the Glycolytic and Krebs’ Cycles, and also participates in the conversion of amino acids into energy. A deficiency of B coenzymes within contracting muscle cells can lead to a weakened pumping of the heart.21 HEART SCIENCE is formulated with high quantities of the most absorbable forms of B Vitamins providing maximum nutrition for the high energy demands of heart cells. Homocysteine Regulators B Vitamins also play a crucial role in the conversion of homocysteine, a group of potentially harmful amino acids produced by the body, to methionine, another more beneficial amino acid. While it is normal for the body to produce some homocysteine, even a small elevation in homocysteine levels can have negative implications. It is well documented that individuals who are genetically predisposed to having elevated homocysteine levels (homocysteinemics) tend to have excessive plaque accumulation in the arteries and premature damage to endothelial cells (cells lining the blood vessels and heart).26 Researchers have found that even those without this genetic abnormality, whose homocysteine levels are much lower than those of homocysteinemics, still have an increased risk for premature endothelial damage and the development of plaque in the arteries.24, 26 One study conducted among normal men and women found that those with the highest levels of homocysteine were twice as likely to have clogged arteries as were those with the lowest levels.24 Furthermore, it was found that the lower the research subjects’ blood levels of folate and B-6, the higher their homocysteine levels.24 Another study found that Folic Acid administered to normal men and women who were not even deficient in folate caused a significant reduction in plasma concentrations of homocysteine!3 In order to regulate homocysteine levels, it is critical to provide the body with sufficient amounts of B-6, B-12, and Folate, whether through the diet or through supplementation. HEART SCIENCE includes high levels of these three nutrients, providing B-6 in the regular and coenzyme form for maximum utilization. The Dangers of Oxidized LDL Cholesterol While many people have heard that high cholesterol levels may negatively affect normal heart function, few people understand exactly what cholesterol is, or how it can become harmful. Cholesterol is a white, waxy substance produced in the liver by all animals, and used for a variety of necessary activities in the body. Your liver also manufactures two main kinds of carrier molecules which transport cholesterol throughout the system: Low Density Lipoprotein (LDL) and High Density Lipoprotein (HDL). Cholesterol is either carried out by LDL from the liver to all tissues in the body where it is deposited, or carried back by HDLs which remove cholesterol deposits from the arteries and carry them to the liver for disposal. Because of this, LDL cholesterol is considered damaging, while HDL is considered protective. Problems occur when there is too much LDL cholesterol in the body and not enough HDL. When the body becomes overloaded with fat, an over-abundance of LDL particles are manufactured to process it, and they in turn become elevated in the body to a degree that the liver cannot handle. Rich in fatty acids and cholesterol, these particles are highly susceptible to free radical attack (oxidation). Once oxidized, LDL particles are no longer recognized by the body, which attacks them with immune cells. Immune cells which are bloated by oxidized lipids (called foam cells) are a key factor in the development of “fatty streaks” — the first sign of excess arterial fat accumulation. The bloated immune cells accumulate in artery lesions and create plaque in blood vessels, leading to obstruction and constriction of the vessels. Plus, these lodged foam cells continue to secrete free radicals into the bloodstream, making the problem worse. The development of lesions in the arteries is not an uncommon problem. Arterial (and all blood vessel) walls are composed of a chemical matrix which holds the endothelial cells in place. That endothelial layer is the first and most important line of defense in preventing large molecules, such as cholesterol and fat, from entering the vessel wall. This matrix is composed of proteins, collagen, elastin, and glycosaminoglycans (amino sugars). Arterial lesions can be caused by suboptimal collagen and elastin synthesis due to three factors: 1. Vitamin C deficiency (since Vitamin C is a key building block for collagen and elastin); 2. excessive consumption of rancid fats, or heavy usage of alcohol or cigarettes; and 3. free radical damage. Once these lesions are created, the body attempts to repair them by depositing LDL cholesterol — similar to the way one would patch a tire. If that cholesterol is not oxidized, i.e. chemically changed to a harmful, unstable molecule, then this process does not create a problem. But when arterial lesions are “patched” with foam cells, arterial walls suffer page 3 page 4 even more damage, because those foam cells release free radicals which can further damage cell membranes. Unfortunately, most people have a lot of oxidized cholesterol floating through the bloodstream. The typical American diet, with its low antioxidant intake and overconsumption of fried and overcooked foods, contributes to the overall levels of harmful oxidized cholesterol. In fact, the average American intake of antioxidants is low even by USRDA standards, making Americans particularly prone to having high levels of oxidized cholesterol. Cholesterol Fighters Fortunately, there are concrete steps you can take to prevent the oxidation of cholesterol, and its subsequent ill effects on health. In addition to cutting out high-cholesterol and fatty foods, supplementation can protect existing cholesterol and all tissue cells — from oxidation. Antioxidants, substances which scavenge and neutralize free radicals, protect the cardiovascular system by halting the oxidation of cholesterol, and helping to prevent plaque accumulation in the arteries and the continual secretion of free radicals by foam cells. Supplementing the diet with high amounts of Vitamin C, a key antioxidant, also encourages a more healthy “patching” of existing lesions by using collagen (made from Vitamin C) instead of cholesterol. HEART SCIENCE contains generous amounts of the following antioxidants for their protective benefits: The Regulating Trio Three nutrients — Magnesium, Potassium, and Taurine — work closely together in the body to help maintain the normal electrical rhythm of the heart, promote proper fluid balance, and prevent excessive Calcium levels from building up in the heart and artery linings. Artery Lining Protectors Your arteries form an integral part of your cardiovascular system, carrying blood away from the heart to nourish other parts of the body. In a healthy heart, blood surges through the arteries with every beat of the heart. The arteries expand with each pulse to accommodate the flow of blood. When arteries become hardened and narrowed by the build-up of plaque, they can’t expand and are not able to transport blood efficiently throughout the body. This inability to open up increases blood pressure, putting a strain on the heart as well as the arteries. HEART SCIENCE includes ingredients specifically geared to protect against plaque formation within arteries and maintain the flexibility of these vital blood vessels. N-Acetyl Glucosamine (NAG) is a key amino sugar which forms the building blocks of mucopolysaccharides. Mucopolysaccharides, which are long chain sugars, are an integral component of connective tissue. They combine to form gel-like matrixes which are present throughout tissues in the body, helping to maintain the elasticity of blood vessels which must continually adapt to the changing pressures of blood flow. Each daily dose of HEART SCIENCE provides 500 mg — a substantial amount — of this vital tissue building block. There is evidence indicating that Silicon, a natural mineral, may protect against plaque formation in the arteries. Silicon is found mainly in connective tissues, where it helps bind the body’s chemical matrix. Bound Silicon is found in high amounts in arterial walls. Researchers have found that there is a steady decline in the Silicon content of the aorta and other arteries as we age. This may be due to the low fiber content of the typical American diet, since fiber is a key dietary source of Silicon.23 HEART SCIENCE includes 400 mg of Horsetail herb extract, a natural source of Silicon. Hawthorn Berry is without question the herb most widely used to encourage normal heart function. The beneficial actions of Hawthorn Berry on cardiac function have been repeatedly demonstrated in experimental studies. Supplementation with Hawthorn Berry has been shown to improve both the blood supply to the heart by dilating coronary vessels, and the metabolic processes in the heart, resulting in normal, strong contractions of the heart muscle.34 Also, Hawthorn may inhibit the angiotensen converting enzyme, which is responsible for converting angiotensen I to angiotensen II, a powerful constrictor of blood vessels.34 Bromelain, a natural enzyme derived from pineapples, has become well-known for its neuromuscular relaxing properties. Researchers have reported favorable results when using Bromelain for soothing vascular linings. Initial research also indicates that Bromelain may break down fibrin, the glue which holds platelets together to form blood clots.6 Capillary Strengtheners Capillaries are the smallest, yet some of the most important, blood vessels. If you think of your cardiovascular system as a series of roads which transport blood and oxygen, then your arteries are akin to interstate highways, your arterioles are the main city boulevards, and your capillaries are local residential streets. Capillaries are so small, in fact, that single red blood cells actually have to fold up to fit through them. Because of their tiny size and the intricate nature of their network throughout the body, capillaries are responsible for actually nourishing each individual tissue cell! Along the length of the capillaries are small openings called slit pores through which oxygen, glucose, and nutrients leave the capillaries and enter the surrounding interstitial fluid. From there, they cross cell membranes and nourish the cells. Similarly, the waste products of cells enter the fluid and cross over into the capillaries, where they are then transported to the liver and kidneys for disposal. If the capillary slit pores are torn or have lesions, then blood proteins and Sodium will leak out and cause the interstitial fluid to take on a more gel-like nature. This makes the transfer of oxygen and nutrients to the cells more difficult, as well as the disposal of cell waste products, turning the fluid into a stagnant swamp instead of a flowing river. In addition to its powerful antioxidant actions, Proanthodyn also helps protect collagen and elastin, the main constituents of tissue in the capillaries, and throughout the body. It is absolutely essential for capillary walls — which are only one cell thick — to be strong and stable, so that they do not allow blood proteins to leak into the interstitial fluid. Once the interstitial fluid takes on a gel-like consistency, the surrounding cells literally become starved from lack of nutrition. The exciting news is that the proanthocyanidins contained in Proanthodyn are among the few substances yet discovered which can help strengthen capillary walls, ensuring the liquid nature of the interstitial fluid.2 Plus, proanthocyanidins help keep capillary and artery walls flexible, allowing for proper blood flow to the heart. Heart Smarts The 1990’s mark a decade of increased awareness among Americans of important health issues. Much of the discussion has revolved around protecting that precious center of life we call the heart. Simple lifestyle change is one of the most effective ways to maintain and protect the functioning of the cardiovascular system. In order to take a holistic approach to heart care, make sure you include plenty of fresh fruits and vegetables (organic, if possible) in your diet, and cut down on fatty and cholesterol-forming foods. Reduce your salt and alcohol intake to a minimum. Try to get regular, sustained aerobic exercise for at least 30 minutes three times a week. Don’t smoke – or if you do smoke, try to eat even more fresh fruits and antioxidant-rich vegetables to counter the amount of free radicals being produced in your body. Lastly, consider adding Source Naturals HEART SCIENCE to your health regimen. HEART SCIENCE, the most comprehensive formula of its kind, provides targeted protection to the entire cardiovascular system. By approaching the promotion of normal heart function on five different levels — through the inclusion of ingredients which supply energy, decrease harmful homocysteine levels, fight cholesterol build-up, help regulate electrical rhythm, and protect artery and capillary linings — HEART SCIENCE is the perfect addition to a holistic approach to heart care. Source Naturals HEART SCIENCE™
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(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=155) Ellagic Active - Raspberry Extract - Promotes Healthy Cells ...
Date:
June 01, 2005 01:22 PM
You may think raspberries are strictly a summertime indulgence. Yet scientists know this simple fruit is far more valuable than a delicious snack or gourmet dessert. Raspberries have the highest content of ellagitannins— amazing health compounds— which are converted into ellagic acids in the body. These compounds are highly regarded for their positive effects on the growth and regulation of various cells and tissues, including those in the breast, pancreas, esophageal, skin, colon and prostate. Ellagic acid is also a powerful antioxidant (even stronger than vitamin C) that supports DNA integrity and promotes overall cell health, according to animal and in-vitro research. Source Naturals offers ELLAGIC ACID in response to a breakthrough in cell research. We strive to be ahead of mainstream nutritional science and are passionate about our commitment to informed health choices. Protective Benefits Dieticians have long stressed the importance of the consumption of fruits and vegetables for general health and well-being, but now these food items are being recognized as even greater contributors to human health. We know that ellagic acid binds to DNA, and acts as a shield, protecting DNA and increasing the expression of the enzyme p21, which arrests division of cells with DNA damage. Raspberries contain phytochemicals that provide protective action: One study showed that ellagic acid was able to induce the production of NAD(P)H:quinone reductase (QR), a major detoxification enzyme. Ellagic acid acts as a free radical scavenger to “bind” irritant-causing chemicals, making them inactive. Ellagic acid stimulates the activity of the enzyme glutathione-S-transferase that supports healthy cell growth. Extensive Research Raspberry is also a traditional remedy in support of the gastrointestinal and respiratory tract. It is used to promote healthy blood vessels, as a mouth and throat remedy and is said to help maintain a “normal, balanced feeling” in the stomach. Research studies on the protective effects of ellagic acid have been extensive—there are approximately 126 published studies. Berries also contain a natural form of salicylates, which provide cardio support. British researchers analyzed the blood of subjects and found salicylates were present from dietary sources, including raspberries and blackberries. Researchers at the National Center for Health Statistics (NCHS) in Hyattsville, Maryland established a connection between reduced health risks and increased intake of salicylates. Animal tests also suggest that red raspberry may reduce levels of glucose (blood sugar) to support normal blood sugar levels. Potent Defense Research in the past decade has determined that ellagic acid is one of the most exciting and promising compounds for its striking effect on cell division, regeneration and growth. While ellagic acid has been found to occur naturally in 46 different foods, red raspberry has been identified as having the highest natural content. Each tablet contains 300 mg of raspberry leaf extract (40% ellagitannins), which is ten times higher than other raspberry products. Source Naturals again joins forces with your natural foods retailer to bring you this unparalleled supplement.
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(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=143) CAT’S CLAW DEFENSE COMPLEX - Health Secrets from the Rainforest
Date:
June 01, 2005 09:59 AM
Standard pharmaceutical drugs came into common use only around the turn of the century. Before that, herbal preparations were administered for health concerns. Today, in nearly every country in the world, herbs are used by health care practitioners as the focal point of health care. Only in the United States is the otherwise widespread use of herbs missing in mainstream culture. But now modern scientific investigation is confirming the benefits of herbal supplementation, which is paving the way for us to reclaim and implement herbs into our everyday lives.
The primary need for preserving the rainforestsRain Forest Herbs Scientists’ knowledge of the varied rain forest flora is far from complete. The plants which have been thus far identified are so elaborate in molecular structure that it’s difficult to understand how these molecules function, let alone how to reproduce them. What is known is that the biodiversity of the rain forest yields numerous biologically active plant constituents which can have a profound influence on supporting the body through times of imbalance. Preserving the rain forest means preserving these precious herbs and the unique constituents contained within them.
Cat’s Claw Defense Complex contains powerful rainforest herbsA Synergistic Blend Source Naturals CAT’S CLAW DEFENSE COMPLEX harnesses the power of some of the most complex botanicals on earth into a synergistic blend of defense-enhancing herbs, each with a unique set of compounds which complement the body’s natural physiology. Source Naturals CAT’S CLAW DEFENSE COMPLEX is the first step in the rediscovery of a long-standing herbal tradition. Source Naturals was the first full-line supplement company to introduce the herbal superstar, Cat’s Claw, and the first to offer it in a combination formula. CAT’S CLAW DEFENSE COMPLEX provides 2000 mg of Cat’s Claw per four tablets – more than many companies’ single ingredient Cat’s Claw products! It combines powerful rain forest herbs like Pau D’Arco and Western herbs such as Aloe Vera and St. John’s Wort with legendary Chinese herbs (Reishi Mushroom and Astragalus). Source Naturals Cat’s Claw Defense Complex also includes two categories of antioxidants for broad spectrum support.
How we ensure quality and potencyCat’s Claw & Pau D’Arco – Peruvian Jungle Discoveries Cat’s Claw was discovered in the depths of the Peruvian Amazon jungle. Researchers have discovered that components extracted from the herb can bolster the body’s innate defenses, address discomforts associated with stress, and support intestinal health. Source Naturals uses only the highest quality Cat’s Claw inner bark – which is at least twenty years old, the amount of time it takes the bark to reach its peak biological activity– and uses a careful process to insure that harvesting the bark doesn’t weaken or destroy the plant. Like all of our herbs, each shipment of Cat’s Claw is also routinely inspected and tested by a trained herbalist to ensure maximum quality and potency. Pau D’Arco is also native to the South American rain forest and, like Cat’s Claw, has a high concentration of active constituents – a combination of anthraquinones and naphthoquinones, primarily lapachol – in the bark of the plant. Each daily dosage of CAT’S CLAW DEFENSE COMPLEX contains 100 mg of Pau D’Arco bark and 100 mg of concentrated Pau D’Arco bark extract for broad spectrum support. Herbs — Adaptogens for Balance Of the Chinese herbs, Siberian Ginseng is one of the best known adaptogens. Adaptogens have a balancing effect, helping us adapt to increased stress levels and other changes, like different altitudes or time zones. Thus, supplementation with Siberian Ginseng can help prevent stress-related health concerns. Schizandra, a small creeping vine with red berries, is a Chinese adaptogen which helps regulate the body’s functions and cleanse it of toxins.
Herbs that energize the body and build resistance to impaired bodily functionThe trio of Chinese mushrooms – Reishi, Shiitake, and Maitake – has been used by Chinese herbalists for centuries, and provides the highest quality natural support for the body’s defenses. Modern science has revealed the true power behind Reishi, Shiitake, and Maitake: high levels of polysaccharides – long chain sugar macromolecules which are known for their protective and cleansing abilities. CAT’S CLAW DEFENSE COMPLEX utilizes only the mycelia biomass of Reishi (200 mg), Shiitake (200 mg), and Maitake (150 mg) to ensure the highest level of activity. Astragalus is the premier tonic – or internal strengthener – of Chinese herbalism. In addition to helping energize the body, Astragalus also builds resistance to weakness and to impaired bodily function. Isatis is a cooling herb which has been shown to have a broad spectrum inhibitory action in in-vitro studies, and helps support normal liver function. Used for thousands of years, the aloe plant has been treasured for its varied uses both externally and internally. Aloe Vera juice is high in mucopolysaccharides, which have been found to have powerful protective capabilities. CAT’S CLAW DEFENSE COMPLEX provides 200 mg of aloe (200:1 concentration) extracted from the whole leaf of the plant.
Why St. John’s Wort is powerful and usefulIt is generally agreed that hypericin and pseudohypericin, two bioflavonoids which are the active constituents in St. John’s Wort, probably act as monoamine oxidase (MAO) inhibitors, which current research has shown are powerful as internal cleansing agents. St. John’s Wort is particularly useful because of its ability to cross the Blood-Brain Barrier, through which many elements are unable to pass.
The liver’s health is essential because of its responsibility for over 500 different functionsAntioxidants and Plantioxidants – Supporting Complete Health Source Naturals CAT’S CLAW DEFENSE COMPLEX includes key liver-supporting antioxidants like Zinc, Beta Carotene, and Vitamin C – nutrients that help protect the liver from stress and pollution induced free radical damage. These three nutrients are also wellknown for their ability to help strengthen the body’s resistance and move through imbalances quickly. The liver is responsible for over 500 functions, including converting vitamins to their active forms, and processing and eliminating waste products from the body; therefore its health is vital. Plantioxidants™ is Source Naturals’ term for Plant-Derived Antioxidant Bioflavonoids. Though most people are only aware of the vitamin and mineral antioxidants, the latest scientific research has indicated that the plant kingdom may provide the most potent antioxidants in the world. Plants, trees, and citrus fruits all contain bioflavonoids (also called polyphenols) – a large group of restorative compounds with similar chemical structures which help protect the body from the ravages of oxidative damage due to free radicals. Some of the Plantioxidants included in CAT’S CLAW DEFENSE COMPLEX are: Quercetin, which helps inhibit the body’s sensitivity to dangerous particles in the air; Proanthodyn, which promotes tissue repair by helping to strengthen collagen and elastin, the two primary structural components in cartilage; Silymarin, which promotes liver-tissue regeneration and optimizes liver-cell function; Green Tea, a remarkably potent antioxidant; and Ginkgo, which is renowned for helping transport oxygen to the brain.
The way to naturally bolster the body’s defensesA Holistic Natural Answer The natural world provides us with a seemingly endless supply of complex herbal compounds with unreplicable and unique constituents so varied and numerous that most doctors aren’t even aware of their existence. Source Naturals would like to change that with CAT’S CLAW DEFENSE COMPLEX – the natural way to bolster the body’s innate defenses. All the ingredients included are at optimal potencies, and in the forms best absorbed by the body. The result? The most powerful, holistic product available to help maintain the structure and function of the natural defenses – Source Naturals CAT’S CLAW DEFENSE COMPLEX.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=130) Red Wine and Resveratrol 
Date:
May 23, 2005 09:20 AM
The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: Implications for protection against coronary heart disease Authors: Pace-Asciak, Cecil R.a; Hahn, Susanb; Diamandis, Eleftherios P.b; Soleas, Georgec; Goldberg, David M. Affiliations: a. Department of Pharmacology, University of Toronto and Research Institute, Hospital for Sick Children, Toronto, Canada b. Department of Clinical Biochemistry, University of Toronto, 100 College Street, Banting Institute, Toronto, Ontario, M5G 1L5, Canada c. Andres Wines Ltd., Grimsby, Ontario, Canada Keywords: Atherosclerosis; Thromboxane B2; Hepoxilins; Anti-oxidants; Resveratrol; Quercetin Abstract: A number of lines of evidence suggest that red wine may be more effective than other alcoholic beverages in decreasing the risk of coronary heart disease (CHD) mortality. This protection over and above that due to ethanol itself may be explained by phenolic components with which red wines are richly endowed. We have studied the effects of the trihydroxy stilbenetrans -resveratrol on human platelet aggregation and on the synthesis of three eicosanoids from arachidonate by platelets, i.e. thromboxane B2 (TxB2), hydroxyheptadecatrienoate (HHT) and 12-hydroxyeicosatetraenoate (12-HETE). These effects were compared with the actions of other wine phenolics (quercetin, catechin and epicatechin) and antioxidants (a-tocopherol, hydroquinone and butylated hydroxytoluene). trans-Resveratrol and quercetin demonstrated a dose-dependent inhibition of both thrombin-induced and ADP-induced platelet aggregation, whereas ethanol inhibited only thrombin-induced aggregation. The other compounds tested were inactive. trans-Resveratrol also inhibited the synthesis of TxB2, HHT, and to a lesser extent 12-HETE, from arachidonate in a dose-dependent manner. Quercetin inhibited only 12-HETE synthesis, and hydroquinone caused slight inhibition of TxB2 synthesis, the remaining compounds being ineffective. De-alcoholized red wines inhibited platelet aggregation; their ability to inhibit the synthesis of TxB2 but not that of 12-HETE from labelled arachidonate by washed human platelets was proportional to their trans-resveratrol concentration. These results are consistent with the notion that trans-resveratrol may contribute to the presumed protective role of red wine against atherosclerosis and CHD.
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If you want to stay healthy, it's important that you know what cellular mitochondria does in the body. Mitochondria are organelles found in the cytoplasm of cells. They are responsible for producing energy for the cell. Without them, the cell would not be able to function properly. We will discuss the role of mitochondria in the body, and how they impact our health. 
Nutritional Supplement
system. More research is needed before it will be recommended for treatment, but so far, the findings have been promising. 
Pau d'arco is known in South America for its healing powers by the Callawaya tribe. These people called the herb taheebo and have been using it for over one thousand years. This herb was used anciently by the Inca civilization's medicine men. Pau d'arco was included in traditions that were passed down through the generations. Pau d'arco has been used to treat cancer and other illnesses since the 1970s in the Santo Andre Hospital in Rio de Janeiro, Brazil. This herb has become a well-known herb for healing and protecting the body from disease. 
It is often referred to as the “everything” herb due to its uses for many disorders. Pau d'arco has been used by many, along with other medications. There seem to be no problems that are associated with the combination. It is also used to help counteract the side effects of some medications and is believed to reduce the liver damage that is caused by some drugs. Many herbalists have used this herb to treat a variety of conditions. It is effective as an immune system enhancer. It can also aid in treating conditions such as cancer, leukemia, tumors, and blood disorders. Pau d'arco is also used to treat the pain of arthritis and also for diabetes, candidiasis, herpes, liver ailments, hypoglycemia, and assimilation of nutrients. 
