Search Term: " GABA "
Can CBD oil help with pain, and can raisins really help you sleep?
March 09, 2019 09:44 AM
1.There is scientific support for the use of cannabis-based medicines to manage chronic pain. However, medicinal marijuana is not availabe in all states. Where it is not available, some are using CBD oil as an alternative. CBD is cannabidiol, a compound derived from cannabis. 2.Hot compresses are sometimes prescribed to treat a condition called blepharitis, which affects the eyelids. It can be difficult to keep a hot compress hot for more than a short time. Hand warmers and reheatable Dry Eye Relief Masks are a good alternative. 3.Eating a handful of raisins before bedtime can reduce the number of bathroom trips during the night.
"I live in an upscale retirement community, and a large number of people here are using marijuana oil to relieve pain without side effects."
Read more: https://www.seattletimes.com/life/wellness/pharmacy-marijuana-senior-citizens/
Is magnesium the secret to ending PMS? Vitamin eases headaches andcramps
February 20, 2019 03:49 PM
The vast majority of women will suffer from common PMS symptoms like cramps, insomnia, headaches, anxiety and mood swings. Roughly five percent of women will suffer more serious symptoms — known as premenstrual dysphoric disorder — involving anger and depression. However, studies suggest that women who take a daily magnesium supplement suffer from less severe PMS symptoms, possibly because magnesium helps promote higher levels of gamma-Aminobutyric acid (GABA), a neurotransmitter which helps regulate sleep. Women who experience exhaustion as a central PMS symptom are particularly likely to need more magnesium.
"According to PubMed Health, during this time, some women feel a wide range of physical discomforts, such as abdominal pain, abdominal cramping, backache, headaches, bloating, weight gain, breast tenderness, possible sleeping issues and digestive discomfort."
Read more: https://www.dailymail.co.uk/health/article-6697649/Is-magnesium-secret-ending-PMS-Vitamin-eases-headaches-cramps.html
Why Are Diabetics More Prone to Heart Diseases?
May 28, 2017 07:14 PM
Diabetes Mellitus is a chronic disease that can lead to many dangerous complications, including coronary heart disease, cerebro-vascular disease, retinopathy, nephropathy, and neuropathy. Of these complications, coronary heart disease is of one of the most worrisome. Having diabetes doubles the risk of heart disease in men and triples the risk in women. This is because people with diabetes have vessel blockages that make them more susceptible to cardiac problems. It is important for people with diabetes to manage their risk by monitoring their blood sugar and lipid levels. They can do this by making lifestyle changes, such as exercising, avoiding smoking, and having appropriate screened tests performed.
Read more: Why Are Diabetics More Prone to Heart Diseases?
'Now I take cannabis oil, I'm starting to get my life back again'
February 22, 2017 12:59 PM
Cannabis oil is one of those controversial things that do wonders for some people but not others. This is one person's positive experience with it. It is legal in a lot of places so is worth a look if you have problems with pain but it's not guaranteed to help anyone. It may or may not.
"Affecting one in every 10,000 people in the UK, it causes small patches of red and swollen tissue, called granulomas, to develop in the organs of the body. It usually affects the lungs and skin. There is no cure."
Master mineral: Why you need the magic of magnesium
December 12, 2016 12:59 PM
There are many essential vitamins and minerals that your body needs to keep it working properly. Magnesium is one of those nutrients, but it is also one that many people become deficient in easily. In addition to helping with nerve, muscle, and immune function, it also promotes normal blood pressure, metabolism, and protein synthesis. Through these processes, magnesium is helpful in promoting good sleep and decreasing anxiety. Not getting enough of this mineral can put us in a bad mood and make it hard for us to sleep and relax.
"Magnesium also helps promote deep, quality sleep by calming your nervous system and activating the GABA receptors in your brain."
What Is GABA And Why Is It Important For The Brain
December 21, 2013 01:22 AM
What is GABA
The human brains need various supplements to make it work better. One such supplement is the gamma aminobutyric acid, abbreviated as GABA. It is the second most important neurotransmitter for the brain. The neurotransmitters allow synapses that transfer information to gray matter in human. This amino acid gives human an inhibiting experience thus making one calm. This makes it possible for one to have a feeling of well being and tranquility.
GABA on Human Body
GABA is useful in the human body because it acts as neurotransmitters. This means you are protected from nerve impulses. This neurotransmitter cools the brain. Research has shown that it helps to increase alpha wave production. This is related to the feeling of relaxation we have in brains.
With enough GABA, it is known to prevent the feeling of insomnia. This comes when neurons firing decreases to make one have a restful sleep. The calming effect helps an individual’s brain to have elevated moods which is an important part for reducing blood pressure. To enable an individual have more concentrations when working, they need to have increased levels of GABA.
Health benefits of GABA
October 07, 2012 05:17 PM
GABA - Gamma-Amino butyric Acid
GABA derived from its chemical name, Gamma-Amino butyric Acid is an amino acid and a neurotransmitter. This acid is produced by the body and is responsible for transmitting information from one cell to another. Scientist claims that GABA supplements can increase the GABA level in the body and thus consequently can be used as a treatment for anxiety, depression, Attention Deficit Hyperactivity Disorder (ADHD), post menstrual syndrome and hypertension.
Though GABA deficiency is rare, depletion of GABA level in the body can occur due to toxins in the environment and other external stressors which may result to the above mentioned disorders.
Other benefit of the GABA in human nutrition apart from the curative effect is, it help people to control their weight, it also relieves pain and injuries ,help one to increase exercise tolerance, also It induces a sense of relaxation thereby reducing stress, increase memory and cognitive function and help reducing insomnia , and it is a good supplement for people with convulsive disorders.
The Health benefits of P-5-P
July 20, 2012 07:51 AM
P-5-P or Pyridoxal-5-phosphate
P-5-P or the most commonly called Pyridoxal-5-phosphate is known to be the most active form of the Vitamin B6. This is known to be converted from organic compounds pyridoxal, pyridoxine and pyridoxamine. The Vitamin P-5-P is a coenzyme which support several other enzymes in the body which play a important role in biosynthesis. This also makes optimum use of the vitamin B6 by improving the body metabolism and many other biological process as well. The vitamin B6 traditionally comes in the form of pyridoxine hydrochloride which the body finds difficult to synthesize in its existing state. Hence, this pyridoxine hydrochloride is processed and is formed as Pyridoxal-5-phosphate to help the body to use the vitamin B6 effectively.
There are a lot of benefits of the vitamin P-5-P
Let us have a look at some of them.
Pyridoxal-5-phosphate uses the information from the genes ad helps to produce proteins.P-5-P is also helpful in the formation of hemoglobin, histamine and neurotransmitters and is also helpful in the metabolism of amino acids, fats and glucose.Pyridoxal-5-phosphate also helps in the conversion of dopa which is a useful substance used in the treatment of Parkinson's disease. Dopa is converted to dopamine which is a neurotransmitter which is produced in the brain and is released by the hypothalamus.
The P5P is also helpful in the utilization of the food sources for the formation of energy and also helps in the easy release of glycogen which is the stored energy.P5P also converts glutamate into GABA which is gamma amino butyric acid which is again a neurotransmitter which is known to be found in the mammals. This is found in their central nervous system.The Pyridoxal-5-phosphate also helpful in the process of decarboxylation which is the conversion of histidine to histamine.
This also converts SAM-e to propylamine which is known to be a precursor of polyamines.The Vitamin P5P is also responsible to lower the homocystenie levels which are caused by the intake of high amounts of methionine.The Vitamin Pyridoxal-5-phosphate helps in the treatment of irregular heartbeat , which is a condition termed as arrhythmia.This plays a important role in the treatment of myocardial infections. This prevents the blood platelets from sticking to each other which usually causes blood clots.The enzymes produced by the Pyridoxal-5-phosphate also helps in the formation of different kinds of amino acid reactions which keeps the carbon ions stable. This process is very important in the metabolism of the cells.The P5P also helps in the metabolism of the amino acids.
Here it helps in converting methionine to cysteine and also converts tryptophan to niacin.Pyridoxal-5-phosphate also plays a vital role in the formation of glucose. This process is known as gluconeogenesis.This also acts a important co-enzyme in the process of glycogenolysis which happens in the liver and muscles and this is known to be a reaction which occurs due to presence of glycogen.The P5P also helps in the formation of antibodies and also assists in the process of hemoglobin synthesis as well.
To keep it simpler, the vitamin P5P performs many functions which is very beneficial to the whole human body. The P5P deficiency can also happen in many individuals and even such symptoms are hard to identify. Any person suffering from the P5P deficiency will have symptoms like muscle weakness, irritability or depression. Consulting a physician and taking necessary supplements will help to overcome the P5P deficiency.
Getting Sleep the Natural Way - What Are Some Natural Remedies For Sleep?
July 04, 2012 08:13 AM
Sleep is a vital part of everyone's life, and without it things can really start to go wrong. It is a proven fact that people who do not get the proper amount of sleep are less healthy then people who sleep properly. There are a lot of ways to get sleep, but many people do not want to take a sleeping pill prescribed by a doctor, or something over the counter. For those that want to get a good night's sleep, but do not want to go buy some harsh drug there are options. Here is a list of some natural ways for someone to catch up on their sleep.
This is an herbal supplement that has been used as a way to cure insomnia for a very long time. Valerian is available in any herbal shop and usually comes in a liquid form. All you need to do is add a few drops to water and drink it right before you go to bed. What makes valerian effective is that the ingredient GABA, which is a neurotransmitter that helps ease the body and make it nice and calm. The best thing about valerian is that it is not addicting and people wake up feeling refreshed in the morning.
Unlike Valerian, melatonin is not anherb, it is a hormone that is found in the body naturally. In the brain there is a gland called the pineal, and it is this little gland that produces melatonin. The debate is out about how effective melatonin is, and people with certain conditions like depression, or auto immune problems should be careful when taking it since this is a hormone associated with the brain.
Ever heard of chamomile tea? Known for its ability to fight bacteria, chamomile is also known as a way to help people fall asleep by calming their body down and causing it to relax. Chamomile tea is also good for the digestion.
Another herbal remedy, kava is known to be good for anxiety. People who take kava as a remedy for anxiety have reported that they tend to sleep better as well.
Every Thanksgiving holiday, people find themselves getting sleepy after they eat and end up taking a post-meal nap. Is it because they ate too much? Well, yes and no. The size of the meal does not matter, but the fact they ate turkey does. Turkey is loaded with tryptophan, though there are supplements also available that contain it. Just be aware that no everyone who eats turkey or takes the pills gets sleepy, some people are immune to the effects of tryptophan.
Everyone needs to sleep if they want to function in their everyday lives. When sleep does not come easy, people tend to turn to the natural world for help. There are a number of remedies available to help a person fall asleep including valerian, melatonin, chamomile, and kava. Before taking any of these remedies or others, please do your research and make sure you get your good night's sleep and nothing more.
How Does GABA Help Brain Function?
May 16, 2012 08:43 AM
Gamma Amino Butyric Acid, GABA, is a neurotransmitter found in central nervous system. It has an inhibitory action on nerve transmission and helps in regulating brain activity and function.
Healthy functioning of brain is important to achieve optimal health. In today's fast paced lifestyle, work related stress and anxiety have taken a toll on man's health. Mental stress and anxiety can cause havoc on the internal systems of the body. According to American Psychological Association, stress can affect the physical as well as mental health of a person. It impairs the brain's ability to block certain toxins and can lead to certain aging conditions such as diabetes, cardiovascular diseases and cancer. Stress can affect brain's normal functioning and affect intellectual abilities and memory. GABA helps in calming the stress and thereby enhancing the functioning capacity of the brain. Let us understand how does GABA help in brain function?
Role of GABA in cerebral cortex:
The nervous system comprises of neurons, brain, spinal cord and neurotransmitters. The role of neurotransmitters is to transmit nerve signals from one neuron to another or from neuron to muscle or gland cell. The most abundant neurotransmitters in cerebral cortex, Glutamate and GABA, have opposite action on the neuron cells.
Glutamate is an excitatory neurotransmitter, which results in neuron fires and sends an electrical impulse down its length. On the other hand, GABA, made from glutamate, has inhibitory action on the nerve cells and does not allow the electrical impulse to pass through the neuron. In case of deficiency of GABA, nerve cells will fire too often and too easily, resulting in wide number of anxiety disorders such as panic attacks, seizure disorders, headaches and other cognitive impairment disorders. Hence, GABA helps in stopping the transmission of nerve impulses from one neuron to another and thereby regulating brain activity. It has a calming effect on the brain.
Once the activity in the brain is regulated and cognitive abilities are restored by GABA, the person can think better and perform better. This natural tranquilizer allows your brain to function more efficiently. Studies have related many higher brain functions such as visual recognition and language comprehension with declining levels of GABA with advancing age. This results in easy firing of neurons by stimulus, slowing down processing of information in brain.
Health benefits of GABA:
According to studies, GABA plays an important role in healthy functioning of mind and body. It helps in:
1. Treating conditions like depression, anxiety, Attention Deficit Hyperactivity Disorder and epilepsy. The result is due to the calming effect of GABA on brain activity. It helps in clear thinking and better reasoning.
2. Preventing age related conditions such as cardiovascular disorder, diabetes and cancer.
3. Inducing a sense of relaxation by providing tranquilizing effect. GABA increases dopamine hormone in the body and gives a sense of euphoria. You remain happy and of course this has a positive effect on sexual system.
4. Relieving pain.
5. Promoting body building and losing extra fat.
GABA can be purchased as a supplement in the form of pill, capsule or powder form. It is a natural alternative for relieving stress and improving brain function.
Herbs For Depression: Alternative Solutions To Improve Your Mood
February 17, 2012 07:29 AM
What Herbs Can Help With Depression?
Depression - Introduction:
Depression is brain system disorders that can make many people weaken from functioning normally during episodic events. Some types of depression actually paralyze people and prevent them from leading a normal life.
In addition, it is important for individuals who suffer from depression to realize, that they do not have to hide this condition and think that they suffer alone. In fact, many people have some form of depressive disorder. Something must be done is to take action to reduce their depression treatment.
Depression - Herbs That Can Help Reduce:
Depression and anxiety are very common in the modern world, and there is no single drug offers an effective cure. However, there are many herbal remedies that can help you reduce depression:
1. St John's Wort (Hypericum perforatum).
St Johns Wortis a eternalcompoundwith littleyellow flowers that originally came from Europe, but also widely used intoAmerican. It is used extensively by European physicians to reducedepression. Two compounds, hypericin and hyperforin, give St. John's Wort potencyto keepmood and fight depression. St. John's Wort also contains flavonoids and proanthoclanidin substances that can affect the peace and balance to the nervous system.
Valerian is the most popular herbs to relieve nervous tension. Sedative effect was first recognized in the seventeenth century, and since then enjoyed a long history of safe use effectively. Research believe that valerian binds to GABA receptors, which produces lower levels of anxiety. This does not completely eliminate anxiety, just change the way that the brain and your body reacts physiologically and give peace to the nervous system.
3. Kava kava.
Kava kava is a plant found in the Pacific Islands. The roots and bark are usually used as a slurry and then combined with cold water to drink. Due to the active compounds in Kava kava, a chemical known as kavalactone, destroyed by high temperatures, use cold or warm water is very important in its preparation. And studies have suggested a correlation between active ingredients and enhanced mood. To be specific, Kava Kava is estimated to have a relaxing impactand reduce fatigue in the human brain.
4. Ginkgo Biloba.
Ginkgo Biloba is the oldest tree used by China to treat various diseases. In the 1700's it has been introduced in Europe. Ginkgo Biloba is mainly composed of active components such as terpene lactones and flavnonoids, which gives a positive effect on mental well-being. With capabilities that are known to increase blood circulation to the brain, this herb has also decreasethe amount of free radicals in the body and brain, so it appears relaxation that can reduce stress or depression.
5. Lavender Oils.
Lavender is a very popular herbal aroma is mainly due to growing importance as a beautiful and essential oils. The smell of lavender oil can stimulate the nerves that send signals to the brain limbic system, which spur the peace and comfort to the physiological function of human emotional. Lavender has been believed by experts to help relieve anxiety, tension, stress and fear that are part of depression.
6. Lemon Balm.
Lemon Balm serves to inhibit the production of thyroid hormones and can help treat primary or secondary brain diseases and to provide a stimulant for the antioxidant that gives relief to your brain space. Some modern studies have found that lemon balm is useful for promoting sleep quality and reduce the effects of depression tranquility.
Chamomile is a very popular herb in Europe and has been widely used for centuries agoas a treatment for some diseases, such as sleep disorders, stress, anxiety, and depression. Other active compositions including flavonoids and matricinid which gives a feeling of relaxation and regulate the nervous system. Now it has proven to be one of the safest herbs on the market to relieve stress.
Although the use of herbs for depression is widely spread, overall there is definitely reaction for the benefits of herbs for reduce depression disorders. Apparent when compared with normally drugs for depression that usually can not serve as the first choice of treatment options. However, when other treatments have failed more established, might have to be used.
February 15, 2012 06:58 AM
Ashwagandha is a popularly known dietary supplement that is commonly grown in India and North America. Also known by the name Indian Winter Cherry, ashwagandha is a product of the brown roots of a shrub that goes by the same name and which is believed to have a wide range of benefits for many ailments. Ashwagandha has always been considered as a very important herb in ayurvedic medicinal systems. This is particularly because of its wide application in curing a wide range of ailments, which has earned it a lot of respect in the eyes of traditional herbal healers. In fact, even modern science has started grasping the herb's potent abilities. Research has already confirmed that ashwagandha possess antioxidant, anti-inflammatory as well as anti-stress properties. This article will hence discuss some of the benefits of ashwagandha to our bodies.
Ashwagandha is particularly recognized for it calming effect on the body. Some researchers have even indicated that it has the ability to induce sleep. Research has demonstrated that it calming and sleep-inducing effects or properties are much similar to that of the popular amino acid known as GABA.
Ashwagandha is also popularly recognized for its ability to ease restlessness or anxiety in addition to reduction of drug withdrawal symptoms. It has the ability to stabilize one's moods in addition to encouraging adrenal recovery which has made it very valuable among herbalists.
The benefits of ashwagandha extend far beyond mood stabilization as it also finds applicable use in helping elderly people to have a better cognitive ability, mental agility as well as enhance their memory and retention. Other than the above, ashwagandha is also known as a very effective remedy for fighting the symptoms of colds as well as coughs.
Recent research has also provided reliable prove that ashwagandha bears a lot of potential ability towards decreasing or inhibiting the growth of cancer cells without having any side effects on other healthy cells.
Ashwagandha is also an antioxidant that contains anti-aging properties and is traditionally recognized for its ability in the nourishment of muscles and the brain as well as strengthening the immune system. Studies have also indicated that the orange berries of the ashwagandha shrub can be tropically used in the treatment of skin ulcers, tumors and carbuncles. Ashwagandha also has anti-inflammatory properties that provide relief to swellings as well as restores blood supply.
It also works as a suppressant to any form of pain. This is due to its “ushan virya” potency properties that help in the eradication of pain in the body. It is also known as an effective remedy for diseases such as osteoarthritis, rheumatoid arthritis, as well as sciatica. It use also has effective application as a remedy for goiter, lymphadenopathy, as well as healing any wounds or injuries.
As a powerful aphrodisiac, ashwagandha helps in the enhancement of sexual energy in addition to long lasting endurance in both men and women. In men, it improves sperm count as well as sperm quality.
Further research has indicated that ashwagandha is an effective treatment for diabetes, constipation, nerve problems, memory loss, impotency, bipolar disorder among a list of other endless physical ailments.
Ashwagandha, taken with a healthy diet as well as accompanied by healthy lifestyle choices is a great way of guaranteeing one's protection from minor ailments as well as promotion of physical strength.
What does GABA Do in the Brain?
November 02, 2011 07:41 AM
GABA or Gamma Amino Butyric Acid is a neurotransmitter of the brain. It is considered to be the main inhibitory brain chemical among mammals. In ordinary terms, it significantly regulates the firing of impulses by the neurons. This chemical is naturally produced by the brain and generally acts as a balancer together with other neurotransmitters. This neurotransmitter has a key role in the regulation of nerve excitability all throughout the nervous system. It effectively maintains the equilibrium of the body and the brain in excitation status. Chemically speaking, GABA is classified as an amino acid. However, GABA is not a building block of protein like the other amino acids. This is the reason why in the medical field, GABA is rarely considered as an amino acid.
Moreover, GABA is the prime brain chemical responsible for the regulation of muscle tone among humans. In a disorder called Spastic Diplegia, the absorption of GABA into the muscles is weakened because of damage nervous tissues and cells. This would significantly lead to hypertonic muscles in which the muscles will experience spasms and can not anymore recognize and process the neurotransmitter GABA. On the other hand, GABA in insects acts as both inhibitory and excitatory neurotransmitter.
As mentioned above, GABA is an inhibitory neurochemical. It functions at the inhibitory synapses of the brain by attaching to receptor sites in the plasma membrane of both pre – and post – synaptic nerves. Once GABA has bind with the receptor sites, it will cause the ion channels to open and permit either the entry of chloride ion which has a negative charge or exit of potassium ion which has a positive charge. Potassium is the main electrolyte inside the cell. This opening of ion channels will then cause the cell to be either hyperpolarized or re – polarized.
During brain development, GABA also plays a significant role. It significantly controls the proliferation of brain progenitor cells and development of synapses as well as the differentiation and maturation of neurites. Furthermore, GABA is also responsible for the growth and development of embryonic and nerve stem cells. It also activates GABA receptors which lead to the halting of cell cycling in the S – phase. As a result, this will limit the growth of cell thus preventing abnormal growth and even malignancies.
If GABA is in inadequate level, muscle tone is disturbed making it always tensed and the mind will keep on working and working because there is no brain chemical to stop it. Therefore, GABA must be importantly maintained within normal limits.
GABA is naturally produced by nerve cells. However, GABA supplement is now available so that adequate amount of such brain chemical will be administered to the body as needed. GABA supplements can enhance the sleep onset and quality. It can also provide a relaxing feeling and reduce stress and muscle over – activity. Other theories also state that it can regulate mood and behavior thus promoting the total well – being of the person. Ongoing studies are being conducted to show more evidence on GABA’s effect with Human Growth Hormones.
Can Alpha GPC Really Help With Memory And Growth ?
September 29, 2011 11:52 AM
What Are The Benefits Of Alpha GPC?
L-Alpha Glycerylphosphorylcholine, or abbreviated as Alpha GPC, is a natural compound which is choline in nature. It is considered to be an acetylcholine precursor which is now being studied as a treatment for the degenerative disease called Alzheimer’s disease. This chemical compound also has a parasympathomimetic property and is widely used as a nutritional supplement for enhancing memory and concentration. The other name of Alpha GPC is Choline Alfoscerate. Alpha GPC has the capacity to rapidly transport choline to the central nervous system by passing through the blood - brain barrier. Alpha GPC can be extracted from highly distilled soy phospholipids such as lecithin. Inside the body, this chemical compound can be found in high quantity in neuronal membranes. Some of its benefits are:
1. IMPROVES ACETYLCHOLINE LEVEL. As mentioned earlier, Alpha GPC can cross the blood – brain barrier. Once inside the brain, it positively influences brain activity by enhancing the production of acetylcholine. Acetylcholine is a neurotransmitter which is responsible for improving the individual’s learning process. Acetylcholine acts on both the peripheral and central nervous system. In the former, this neurotransmitter functions as the main neurotransmitter in the autonomic nervous system. It is also involved in the contraction of body muscles. In the latter, acetylcholine acts as an anti – excitatory chemical in the cholinergic system.
2. MEMBRANE COMPONENT. Another health benefit of Alpha GPC is that it can effectively protect nerve cells thus improving the transmission of impulse. Aside from maintaining the integrity of the nerves and nerve cells, Alpha GPC also serves as a precursor of the phospholipids found on membranes.
3. INCREASE HUMAN GROWTH HORMONE. Studies on Alpha GPC have revealed that it can relatively influence the action of the body’s Growth Hormone – Releasing Hormone (GHrH), thus improving the release of growth hormones. In addition, it can also enhance the effects of human growth hormone especially among young individuals.
4. A MODALITY FOR DEMENTIA. Alpha GPC has been long studied for the treatment of senile dementia. Initial result of such studies revealed that patients supplemented with Alpha GPC showed improvement but on a smaller extent. Further studies are still being conducted so that efficacy and safety as well as the appropriate dosage will be determined.
5. INFLUENCES GABA. Studies reveal that Alpha GPC significantly increase the synthesis and release of Gamma Amino – Butyric Acid or GABA. Increased synthesis of GABA is also potentiated by atropine. GABA is considered as the principal inhibitory brain chemical among mammals. It has a significant role in controlling neuronal excitation all over the nervous system. Like acetylcholine, GABA is also one of the primary responsible chemicals for the control of muscle tone.
Alpha GPC is formulated as supplement. It is available in 300 to 1,200 milligram oral supplements. Though it is generally safe, it is important that you should consult your doctor first before using this supplement. This would significantly avoid the occurrence of adverse effects and drug interactions. Appropriate dosage will also be determined by your doctor. Remember, any medication or supplement varies from person to person on its therapeutic and adverse effects.
Can The Herb Passion Flower Help Pain?
September 08, 2011 11:43 AM
Furthermore, it is able to do so by not affecting respiratory activity and mental health functions unlike many of the synthetic pharmaceutical drugs available today for use of sedation. There are many Americans suffering from chronic pain and other symptoms that involve incessant pain in the muscles and other parts of the body. Many of us look towards medication for some relief however the side effects are enormous. Because in the same way that this medication can alleviate pain it also hinders many of our nervous system functions and the most important of which is brain functions. Side effects can range from being groggy to lack of mental alertness.
How passion flower works
Passionflower has a long history dating back to the ancient worlds to have uses against anxiety, insomnia, restlessness, epilepsy, and other conditions of hyperactivity because of its calming properties and this is in a general sense however let us try to look into how it is able to have these properties and how it translates to bodily functions. The key so far to its potency is its affects on muscle tension and mental conflicts. This is the same reason why a lot of medication in the market today has some sort of derivative of passionflower. It has been part of many nerve disorder treatments to aid in further relief of anxiety and even has shown signs of being helpful towards blood pressure regulation and aid in relief of heart palpitations.
Although it has been shown not be as strong as most drugs when it is not processed and just left as close to its natural form as possible it also does not have the same side effects and prevents addiction as well unlike most medications. The main way that it is able to play a big role in any efficient sedation process to relieve pain is because it has the ability to lessen neurotransmitter production or even as some research suggests block it all together through increasing GABA (gamma-aminobutyric acid) production which is a neurotransmitter inhibitor. Additionally it also has potent phytochemicals that studies have to shown to inhibit prostaglandin which is a chemical responsible for letting us feel pain. Therefore, passion flower could be used as a pain remedy!
Grab some passion flower today and feel the difference.
What Are The Symptoms Of GABA Deficiency?
September 05, 2011 11:19 AM
In this modern age many of our illnesses comes from the lack of certain substances, chemicals or enzymes just to name a few possibilities but the list could go on. They are called so many different things but they all have one thing in common and that’s being essential to our day to day bodily functions. In this writing we will look into possible symptoms of GABA deficiency.
GABA or Gamma aminobutyric Acid
Gamma-aminobutyric acid (GABA) is an essential neurotransmitter in the body. Its main function is as an inhibitor which mainly focuses on regulating neuronal excitability throughout the nervous system and another function that this chemical has it to aid in the regulation of muscle tone in human beings. In terms of its chemical makeup it is essentially an amino acid however it is very seldom to be called that in the scientific community.
The reason mainly for this is because it is not an alpha amino acid and is never incorporated with a protein which what the term amino acid is commonly reserved for in the medical science world. GABA, to keep things simple is mainly essential to the nervous system and brain health. It is responsible for the maintenance of our nervous system functions and some parts of the brain by allowing the nerves to complete the processes needed to get all the necessary chemicals to keep nerve functions healthy.
GABA Deficiency and Symptoms
As a neurotransmitter it has the ability to influence relaxation and aid in preventing anxiety when GABA levels are too low in the body there are a variety of unwanted effects that can happen. The reasons for GABA being too low in the body can possibly be two things, it can either be genetic or acquired reasons. Just to name some specific possible factors in GABA levels being low are chronic stress and chronic pain. Furthermore, inadequate sleep, caffeine excess, excessive electromagnetic radiation and progesterone deficiency may also further initiate the lowering of GABA levels in the body. With GABA being an essential neurotransmitter the first symptom that may arise with a lack of this brain chemical in the body is expectedly anxiety and depression.
Many studies have shown individuals that suffer from some form of anxiety and depression commonly has low levels of GABA in their body and it has also confirmed that when subjects are supplemented with this brain chemical in an attempt to raise levels in the body they are alleviated of the incidence of depression and anxiety. Feeling panicky, nervous and having a low tolerance for stress are also possible symptoms and also have been shown in researches to be alleviated through GABA supplementation. The most common medication for people suffering from these symptoms is valium and as most of us know, even for those who haven’t used it, it has nasty side effects and one of them is addiction to it however more natural means of supplementing with GABA will be able to give the same desired improvements but with lesser side effects.
What Vitamins And Minerals Are For Mental Alertness?
August 29, 2011 10:33 AM
There are many vitamins and minerals which can help improve the health and functioning of the nervous system. Vitamins and minerals are significantly involved in many biological processes of the body. It influences the activities of the organs of the body including the brain. In fact, deficiencies on vitamins and minerals may result to psychological or even psychiatric symptoms in certain individuals. People with psychiatric problems are also prescribed with vitamin and mineral supplements which serve as one of its conventional treatment.
The vitamins and minerals which are good for the improvement of brain function and improvement of mental alertness are the following:
1. THIAMINE OR VITAMIN B1. Generally, insufficient amount of this enzyme may result to mild psychiatric symptoms. Studies revealed that people with inadequate amount of this vitamin has the symptoms of fearfulness, anxiety, depression, agitation and behavioral instability. This vitamin is necessary for the activity the body’s enzyme called pyruvate dehydrogenase. This enzyme is required for the conversion of pyruvate to acetyl – coenzyme A. If pyruvate is not catalyzed into acetyl – coenzyme A, the excess pyruvate in the body might be converted into lactate which can cause muscle pains and also psychiatric symptoms such as anxiety. Deficiency of this vitamin must be suspected when the person is alcoholic or malnourished.
2. RIBOFLAVIN OR VITAMIN B2. This vitamin is closely associated with major depression in relation to oxidative stress. Riboflavin is required for the metabolism of protein, fats and carbohydrates. The building blocks of these macronutrients are important for the maintenance of brain health and proper functioning of the nervous system. It can improve the energy levels and functioning of the brain, thus improving an individual’s mental alertness.
3. PYRIDOXINE OR VITAMIN B6. Studies show that low level of vitamin B6 is directly related to depression. Inside the body, pyridoxine is converted into its biochemical active form called pyridoxal phosphate which is important for mental alertness and brain functioning. Pyridoxine acts as a coenzyme involved in the synthesis of brain chemicals such as serotonin, dopamine and gamma aminobutyric acid (GABA). This vitamin is also involved in the metabolism of carbohydrates and amino acids which are essential for boosting energy levels.
4. COBALAMIN OR VITAMIN B12. Deficiency of this vitamin is closely related to decrease mental functioning. Vitamin B12 is a cofactor of the enzyme methionine synthase which is important in the conversion of homocysteine to methionine. This is required for the production of energy in fatty acids and proteins which is important for the methylation reactions of brain chemicals.
5. VITAMIN C. This vitamin is considered to be a cofactor of the neurotransmitter dopamine and is involved in the conversion of dopamine to norepinephrine. These brain chemicals are important for the maintenance of proper mental alertness.
6. FOLATE. Decreased mental alertness and depression is a common symptom of low levels of folate in the body. This mineral is involved in the methylation and synthesis of DNA. It is important for the development of brain function and improvement of mental alertness.
7. MAGNESIUM. This mineral is involved in many reactions of the body. Individuals with decreased mental alertness are found to have low levels of magnesium in their cerebrospinal fluids.
8. ZINC. This is a mineral which is important in the catalyses of many enzyme sin the body. It is found in high amount in the brain which is important for nervous activities.
How Does Taurine Help the Brain?
May 13, 2011 01:09 PM
Taurine is an amino acid often added to energy drinks. There have been several theories on how taurine affects brain chemicals and improve cognitive function. For many years, it has been compared to caffeine due to its effects on the human brain that appear to enhance mood. Its exact mechanisms of action remain a mystery to the scientific community, but recent studies are believed to be closing in.
It has long been known that taurine crosses the blood brain barrier, allowing it to exert some effects on several neurotransmitters found in the central nervous system. It has been tied to the alleviation of many mental illnesses, such as epilepsy, post traumatic stress disorder, clinical depression, bipolar disorder, and anxiety, making it the subject of a number of studies in the past few years.
Rebalances Brain Chemicals
It has been postulated that taurine influences the activities of neurotransmitters in the brain, but only recently has brain scientists been able to actually track its activities in the brain. A team of researchers at Cornell University managed to find a site for the neurological activity of taurine, with initial results pointing to its relationship with gamma the neurotransmitter aminobutyric acid, or GABA. The researchers do not discount the possibility that taurine may even have a receptor of its own.
Whether taurine interacts with brain chemicals is no longer debatable as it creates homeostasis in the central nervous system. It acts on receptors that the researchers discovered to be the same receptors present in GABAergic mechanisms. That being said, scientists remain inconclusive as to how its interaction with GABA receptors provides energy-boosting benefits as it is marketed in the food and drug industries.
Prevents Neuron Damage
The scientific community is convinced that taurine has neuroprotective properties. High levels of taurine in the brain have been observed to protect brain tissues from cerebral ischemia. Taurine has been linked to many metabolic pathways that are known to promote neurological health, such as the activation of glycine receptors and the regulation of enzymes called cysteine-dependent aspartate-directed proteases.
In addition, taurine serves as antioxidants that protect nerve cells from cellular damage brought on by oxidative stress. The presence of taurine within cells reduces damage from calcium excesses and increases mitochondrial events. For decades, supplementation of taurine has benefited sufferers of brain ischemia, epileptic seizures, panic attacks, anxiety symptoms, and even alcohol withdrawal.
Enhances Cognitive Function
Taurine has already been associated with physiological functions the hypothalamus controls, such as sleep-wake cycle and responses to fatigue. In several laboratory studies, administrations of taurine by way of intraperitoneal injection have successfully induced social interaction in animal subjects. It is one of the amino acids that affect cognitive development, especially in children. While it is one of the most abundant amino acids in the brain, it is depleted as we age, making supplementation a good option.
Protect your brain with Taurine by taking it daily!
How Does Passion Flower Help Me Relax ?
April 07, 2011 01:39 PM
Passion flower refers to a group of flowering plants that belongs to the genus Passiflora, comprising of up to 500 species. The commonly known plant species of Passiflora are climbing vines with a woody stem system although there are a few herbaceous shrubs. They are found across the globe with the exception of arctic and sub-Saharan regions and easily recognizable by their unique flower structure which often contains prominent styles and stamens. Passiflora incarnata, or more commonly known as Maypop in the vernacular, has a long association with folk medicine of American Indians, who use various parts of the plant as a relaxant.
Different species of Passiflora are called different names, but the trivial name passion flower pertains to the corona that resembles the crown of thorns worn by Jesus. Moreover, the Christians have ascribed many symbolisms for the intricate parts of the flower. For example, the ovary is believed to represent the Holy Grail. Early European settlers in the Americas discovered the calming effects of teas made from Passiflora species through the Indians, and popularized its use against anxiety soon after in Europe.
Produces Tranquilizing Effects
Several studies have investigated the effects of passion flower on human health, with a few comparing it to the drug exazepam. Its mechanism of action is still under scrutiny, but scientists are convinced that its sedative effects are very similar to the herbs Valeriana officinalis and Piper methysticum. More often than not, it is used in combination with these two herbs. As a mild relaxant with a slow onset of action, Passiflora incarnata, or Maypop, have been documented to benefit individuals suffering from irritability, insomnia, and agitation. In conjunction with a drug called clonidine, it also appears to relieve muscle tremors.
Increases Inhibitory Brain Chemicals
It has long been postulated that passion flower works on the principle of raising the levels of inhibitory neurotransmitters, such as gamma-aminobutryric acid, or GABA. Glutamic acid, the biological precursor of gamma-aminobutyric acid, has been linked to neuronal excitotoxicity that leads to many known diseases of the nervous system. By aiding the metabolic pathway responsible for converting glutamate into gamma-aminobutyric acid, passion flower not only increases the amounts of the chief inhibitory brain chemicals in the human brain and the rest of the central nervous system, but also lowers the levels of excitatory neurotransmitters. This results in a drop in neuronal activities and a reduced risk of excitotoxicity, which translated into a more relaxed feeling.
Alleviates Physical Fatigue
Passion flower is known to counter the harmful effects of stress. In addition to alleviating psychiatric symptoms of anxiety, Passiflora incarnata has also been tied to the treatment of muscle weakness characteristic of fibromyalgia. It is one of the herbal nervines used in combination with other herbal adaptogens in combating physical fatigue due to long hours at work and the consequent sleep deprivation. Fortunately, passion flower is generally considered safe and nontoxic, with dosages equivalent to food proportions in general.
Passion flower can be taken with valerian and skull cap to help calm the mind and body when under intense stress. Give it a try and See for yourself!
The Amino Acid Glycine Is A Component Of Collagen And Essential For Good Health?
March 23, 2011 03:45 PM
What Is The Amino Acid Glycine And How does it Work In the Body
Glycine is the smallest amino acid found in the human body. It is present not only in water-based environments but also in fatty tissues. Being one of the earliest amino acids to be discovered, it has been a subject of numerous studies in the last century. The abundance of data points to its indispensable role in maintaining the overall health of the body since it is quite ubiquitous at the cellular level.
Supplies Amino Acid Requirement of Proteins in Cells
It is a widely accepted fact that glycine is an amino acid necessitated for the production of proteins that the human body uses and accounts for more than 30 per cent of the protein group called collagen. Human cells in particular utilize glycine in manufacturing fibrous and muscle tissues, the reason why it has been in use in treatment of degenerative diseases. The total absence of glycine in the human body is impossible, given the role it plays in protein synthesis, but low levels of glycine can be harmful.
Converts into Glucose and Helps Regulate Blood Sugar
Glucogenic amino acids are a number of amino acids that can be converted into glucose. First on the list is glycine, which does not only aid against a sudden drop in blood sugar but also provides the body with enough glucose to support cellular functions. Feelings of weakness characteristic of fibromyalgia and chronic fatigue are often attributable to an impaired capacity to produce enough energy. The process of gluconeogenesis converts non-carbohydrate compounds into glucose as a response.
Displays Inhibitory and Excitatory Neuronal Activities
While GABA is the primary inhibitory neurotransmitter in human beings, glycine is also known to display inhibitory activities in the central nervous system. The spinal cord, brainstem, and the forebrain have all been identified to employ this amino acid in gylcinergic neurotransmission, which may be inhibitory or excitatory. It is postulated that glycine plays a major role in various mental disorders, and several studies concerning its psychoactive potential are well underway.
Scavenges Free Radicals and Reactive Oxygen Species
Although it is not considered an essential amino acid, which means the body produces quantities adequate to support physiological functions, depleting levels of glycine is not uncommon especially in individuals suffering from malnutrition and malabsorption. Glycine supplements have seen a surge in popularity in the latter half of the century as they are also known for their antioxidant activities. Enzymes responsible for antioxidant defenses necessitate glycine, which is an antioxidant in itself.
Supplementation of glycine has risen in the past few years especially when studies associating this amino acid to degenerative diseases have started to surface. A number of scientists believed that age-related and other degenerative diseases such as arthritis and osteoporosis may be classified as deficiency diseases in that these diseases can easily be prevented or reversed with diet modifications. The incorporation of glycine in food products has also been reported to contribute to the upkeep of protein complexes needed by joints, muscles, and other parts of the body.
Taurine - Essential or Non-Essential Amino Acid - You Decide?
February 17, 2011 10:56 AM
Amino Acid Taurine Is Essential For More Than You Think
Taurine is an organic compound with acidic properties, which is synthesized in the pancreas in adults, but an essential amino acid in infants. Many neutraceutical products for infants are fortified with taurine, inasmuch as some newborns do not have the enzymes required to synthesize taurine. Taurine deficiency in adults results from deficiencies in other organic compounds, notably methionine and cysteine, which are its immediate precursors within the body.
Helps in Brain Development
It has long been postulated that taurine plays an important role in the human brain, especially in infants, protecting the nerve cells from possible neonatal damages. Taurine continues to affect the nervous system as we age, acting on gamma-aminobutyric acid, or GABA, and consequently enhances inhibitory synaptic transmissions. In addition, taurine is alleged to stimulate continuous activation of synapses characteristic of long-term potentiation, which memory and learning ability stem from.
Stabilizes Glucose Levels
Taurine is a powerful inhibitor of glycation, a process by which sugar molecules attach themselves to other biomolecules without the aid of enzymes, and thus subsequently impair the functions of these biomolecules. This process may take place inside or outside the body, but the substances that result from this process, which are referred to as advanced glycation end-products or AGEs, contribute to the formation of a number of major disorders in later life such as cardiovascular diseases, Alzheimer’s disease, age-related deafness and blindness, and cancer. Taurine keeps the cells from taking up AGEs from the blood, which is slowly excreted in the urine.
Regulates Adipose Tissues
It has also been observed that dietary taurine influences the metabolic pathways that give rise to the formation of adipose tissues, the fat reserves of the human body. These fat depot appear anywhere in the body, but are commonly tied to the subcutaneous fats, those that we see on the belly, chest, arms, and thighs. Moreover, body fat percentage has been an indicator of obesity, which is central to the use of taurine in regulating adipose tissues.
Influences Lipid Absorption
Taurine is a major component of bile, the fluid produced by the liver, stored in the gallbladder, and secreted in the small intestines to aid in the digestion of triglycerides, cholesterol, and other lipids. Also, several studies point to the effect of taurine on the binding of proteins to lipids to form lipoproteins, compounds that have been notoriously labeled as bad cholesterol. Not surprisingly, taurine has been suggested to maintain healthy levels of blood cholesterol and prevent cardiovascular diseases.
Fights Oxidative Stress
Sodas have become a part of our daily diet today, but little did we know that they are risk factors for oxidative stress, the continued peroxidation of cellular structures. Fructose in sodas and other sweetened beverages is the most dangerous of all sugars, inasmuch as it releases by-products called AGEs, which are highly reactive to oxidation. AGEs do not get excreted right away and are instead absorbed by cells, leading to irreversible damages to neuronal and vascular tissues in later life. Intake of taurine removes this problem.
Have you had your Taurine Today?
Fight Anxiety Disorders Naturally
December 14, 2010 04:27 PM
Do you suffer from an Anxiety Disorder?
Before considering how to test for anxiety disorders and discussing natural supplements that can help we should first discuss what anxiety disorders are - what the term means and if there are degrees of anxiety disorders as there are of depression and stress. First, what is anxiety?
Anxiety is a natural reaction to stress and it is anxiety that makes you worry about the consequences of not studying for an exam - so you study. It focuses you on problems so that you will be more likely to solve them, and helps you to perform better whatever you are doing. However, it can get out of hand and these positive mental processes become negative anxiety disorders.
With some people, anxiety becomes a dread of situations that were once everyday occurrences and can make your life a misery. Here are some forms of anxiety disorder.
Typical Anxiety Disorders
General Anxiety Disorder
Its symptoms include excessive sweating, worry, headaches, irritability, difficulty in sleeping, tiredness and tension in your muscles. It can lead to substance abuse and deep depression if left untreated.
These are three typical forms of anxiety, but how do you test for anxieties? Here are some tests that are used, beginning with the easiest - doing it yourself!
Testing for Anxiety Disorders
Many that believe they may have an anxiety disorder either tend to panic or go into a depression. It is far better to carry out a self-test. This anxiety test is very simple: simply tick which of the symptoms below you have experienced in the past six months:
I can't relax
I am always worried about something.
I get headaches for no apparent reason
I frequently sweat a lot and get hot flashes
I have no time for anybody and am easily annoyed
I find it hard to sleep and I often wake up during the night
My attention keeps wandering and I can't focus on anything
I sometimes get so worried I want to be sick or have a lump in my throat
If you have ticked more than three then perhaps you should pay your doctor a visit, or try some of the recommendations below.
b) Doctors' Tests
If you feel you might be suffering some form of anxiety disorder you should consult your doctor, particularly if you have tried the self test above and it indicates that you might be. Your doctor might carry out various tests for your general health, and if it is felt necessary you may be asked about your family history: is there any history of mental problems in the family, particularly with your mother or father.
Other questions may appertain to your own physical and mental background, such as have you been stressed for any reason lately, have you suffered anxiety or panic attacks in the past and what is your normal use of prescription and non-prescription medications and drugs. Do you smoke, drink or take any social drugs.
It is important that you are totally honest: the doctor is not judging you, simply trying to find the cause of your problem. Under the terms of their oath they cannot divulge anything you tell them to anyone else, so be honest and let them help you. Among the tests you will be given will be to declare all your history of anxiety-related symptoms. To achieve that, you will be asked a series of questions while the doctor assesses your mental condition.
Finally, you may be referred to a psychiatrist who will be able to help you more than your doctor. Psychiatrists have a good record in resolving anxiety disorders, but once you are diagnosed positively, what then? Chemical drugs? Or perhaps you would prefer something more natural such as herbal remedies.
Herbal Remedies for Anxiety
There are a number of herbs that can be used to treat anxiety disorders. Here are the more commonly used of these:
Passion flower contains the active substances maltol and ethylmaltol that your body's biochemistry uses to increase the concentration of GABA (gamma-butyric acid) in your brain. GABA is a neurotransmitter that calms you and helps you to relax and forget anything that is making you anxious. It relieves muscle tension, can lower your blood pressure and some equate its effect to that of Valium: although it is totally different chemically it is similar in its effect. It offers a sedative effect and helps you sleep.
Kava Kava root
Kava kava. Generally just referred to as kava, comes from the Pacific and the kavalactones it contains increase the concentration of neurotransmitters in your vascular system, particularly serotonin, the feel-good substance. Its sedative effects have been likened to that of alcohol, and it can certainly give you a lift and certainly helps you worry less as it reduces the negative symptoms of stress and depression.
St. John's Wort
St. John's wort is a well-known anti-depressant and it can also help reduce the symptom of anxiety. The hyperforin the plant contains helps to improve the brain's content of the neurotransmitters serotonin, dopamine and norepinephrine that make you feel good, and St. John's wort certainly washes away your anxiety. Not only that, but the napththodianthrone in another of its important components, hypericin, promotes a reduction in depression through the inhibition of monoamine oxidase, a pro-depressive enzyme.
An extract of valerian root can help you to relax and sleep well, and this can often be enough to prevent your anxiety attacks. A lot depends on their cause, but if the attacks are mild and don't require extensive medical or psychiatric intervention, then valerian can help, particularly in treating stress-related anxiety. Make sure you stick to the recommended dose because valerian can be dangerous if taken to excess.
The four herbal remedies above should between them be all you need to treat your anxiety. One major problem is that, just like any chemical drugs, they only treat the symptoms and not the underlying cause which is something you and your physician will have to work on yourselves.
However, until then, the above herbal remedies for anxiety disorders are generally safer to use than prescription drugs and each has a well proven effect, both on the symptoms of anxiety and on depression.
Herbs For Depression
December 13, 2010 12:34 PM
Fight Depression with Natural Herbs
Before discussing treating depression with natural herbs we should first consider depression itself: what is it and what causes people to become depressed? Psychiatrists and psychologists will suggest a number of definitions although most experts agree that there are two forms of depression.
Causes of Depression
Exogenous depression comes about as a result of external factors such as bereavement, heavy debt, job loss, etc, while endogenous depression comes from within and is believed to be due to biochemical problems, including food allergies, hormonal changes, thyroid problems, nutritional deficiencies, particularly Vitamin B deficiency, and addictions. There are many other reasons for people becoming depressed, some of which can be established by the particular symptoms of the individual.
In many cases of depression the external factors are often easier to treat than those due to internal factors. Many exogenous causes of depression such as bereavement are alleviated through time, while causes such as job loss and debt can be resolved once the cause has been rectified: thus, if the patient is no longer in debt or is re-employed, the depression tends to disappear with the cause.
Symptoms of Depression
Depression is not diagnosed from a single symptom, but from a number of symptoms that can point to a person being clinically depressed and requiring treatment. Among the symptoms of depression are:
Prolonged periods of sadness or despair
Forms of Depression
Many normal people can suffer one or two of the above systems, and would not be diagnosed as depressed because of it. We can all get mood swings, feel a bit worthless now and again or be unable to concentrate or focus at times, but that does not mean we are clinically depressed.
Depression would not be diagnosed in a patient with just one of these symptoms but five or more likely would be. In fact, the American Psychiatric Association in the Diagnostic and Statistical Manual of Mental Disorders deem the patient suffering clinical depression if displaying 5 or more of the bottom 8 symptoms above for a month or more. This is believed to be the case with around 17 million Americans so it is a significant problem.
Manic depression is otherwise known as bipolar disorder, where patients have large mood swings from high and extreme hyperactivity and excitability to very low deeply depressive moods and is a clinical condition generally treated using drugs.
Treatment of Depression With Natural Herbs
The usual treatments are drugs that often have undesirable side effects; so many people are trying natural remedies instead. There are a number of herbs that can be used to treat depression, one of the most familiar being St. John's Wort. However, there are others, and here is a synopsis of each.
St. John's Wort
St. John's wort (hypericum perforatum) is likely the best known herbal treatment for depression. In fact, in Germany it is prescribed by doctors to children and adolescents for the treatment of mild depression and is available over the counter in many countries.
However, it can also be used in cases of severe depression, and a report in the Cochrane Database Review[8(4)] by K. Linde, M.M. Berner and L. Kriston in 2008 stated that of 29 separate tests carried out on a total of over 5,000 patients, the conclusion was that St. John's wort extracts were at least as good in treating severe depression with 5 times lower side-effects as tricyclic antidepressants and twice lower than the new selective serotonin reuptake inhibitors (SSRI).
It should be stated, however, that one trial on 340 subjects indicated no improvement over a placebo. However, the anti-depressive drug sertraline (Zoloft) was also shown to be no better than the placebo in this test, so some doubts must lie regarding its accuracy. Of all the herbal treatments, St. John's wort has had most testing carried out and it seems to be effective in treating mild to severe depression although not all experts are yet agreed.
Kava Kava Root
Kava kava can be used to treat depression and anxiety, largely due its content of kavalactones that are believed to increase the amount of a number of neurotransmitters in the blood, including the feel-good neurotransmitter serotonin. Kava kava root is mildly intoxicating, having much the same effect as alcohol, and can also reduce the symptoms of depression and anxiety.
However, it is doubtful if its effects are permanent and so it may be less of a depression cure as a short-medium term treatment. Its effects are also variable on different people, some describing it as making them feel relaxed and 'dreamy', while others find it therapeutic and making them feel better in themselves.
Kava kava should not be taken without your doctor knowing about because there have been concerns about its effect on the liver if taken in excess. A European-wide ban was lifted about two years ago after testing found the risks of taking it to be very low. It has been used for centuries as an intoxicating drink on islands such as Fiji.
Passion flower has been used for centuries to treat anxiety, stress and depression, its active ingredients believed to be maltol and ethylmaltol that help to increase the level of gamma-aminobutyric acid (GABA) in the brain. GABA is one of the brain's key neurotransmitters and has been described by some as the brain's own 'Valium' supply.
Through the intervention of GABA, passion flower extract helps in reducing anxiety levels and makes you feel a lot calmer. If you suffer forms of depression that make you hyper or excitable, passion flower will help to reduce this and also helps to cure insomnia. It is a component of many natural sleeping pills.
These are just three natural substances that can be used to treat depression. However, you must inform your doctor or physician if you decide to take them since they may interfere with or change the effect of any antidepressant drug you are currently taking.
Call today for natural remedies for depression
Natural Anxiety Remedies
November 11, 2010 05:44 PM
Anxiety disorder is a much more common problem than what was once thought. It often affects people in their teenage years through middle age and later. Anxiety disorder appears to affect twice as many women as men. However, there may not be that wide of a disparity between the sexes. Psychologists simply believe that men are far less prone to report or even acknowledge that they have a problem of this nature. Anxiety disorders can either be acute or chronic. Acute anxiety disorder manifests itself in episodes that are commonly known as panic attacks. A panic attack occurs when the body’s natural “fight or flight” reaction occurs at the wrong time. This is a complex response in which the body prepares itself to deal with an emergency situation. Stress can often cause the body to produce more adrenal hormones, especially adrenaline. The increased production of adrenaline causes the body to step up its metabolism of proteins, fats, and carbohydrates to quickly produce energy for the body to use. Additionally, the muscles tense up and the heartbeat and breathing become more rapid.
When faced with an assault, accident, or a natural disaster, this type of reaction is perfectly normal. However, the symptoms that are caused by the surge in adrenaline can be distressing and frightening when they occur at the wrong time. A person having a panic attack is often overwhelmed by a sense of impending disaster or death, which makes it impossible to think clearly. Other feelings that can accompany a panic attack include shortness of breath, a smothering, claustrophobic sensation, heart palpitations, chest pain, dizziness, hot flashes or chills, trembling, numbness or tingling sensations in the extremities, sweating, nausea, a feeling of unreality, and a distorted perception of the passage of time. This disorder can eventually have other cumulative effects such as generalized aches and pains, muscular twitching and stiffness, depression, insomnia, nightmares and early waking, decreased libido, and abnormal feelings of tension with an accompanying inability to relax.
Panic attacks are usually abrupt and intense, occurring at any time of the day or night, and lasting from several seconds up to half an hour. To the panic sufferer, it often feels as though they are much longer. A person having a panic attack sometimes believes that he or she is experiencing a heart attack or stroke. The attacks themselves are very unpredictable, with some people experiencing one every few weeks, and others having several each day. Panic attacks are often triggered by stress or certain emotions, but they can also be a response to certain foods, drugs, or illness.
Many people with acute anxiety disorder become afraid of being alone and visiting public places because they fear having a panic attack. This only adds to the level of anxiety and leads to abnormally restricted lives. Psychologists often believe that at least in some cases, panic attacks are self-induced, meaning that the fear of the panic attack is the very thing that brings it on. The following nutrients are recommended for dealing with anxiety disorders: calcium, magnesium, B1, B12, multivitamin and mineral complex, SAMe, vitamin B, vitamin C, vitamin E, zinc, chromium picolinate, DLPA, L-glutamine, coenzyme A, essential fatty acids, GABA, melatonin, bilberry, ginkgo biloba, milk thistle, catnip, chamomile, cramp bark, kava kava, hops, linden flower, motherwort, passionflower, skullcap, fennel, lemon balm, willow bark, feverfew, St. John’s wort, skullcap, valerian root, and mandarin oil.
Natural vitamins and herbs can be found at VitaNet ®, LLC Vitamin Store.
June 26, 2009 12:15 PM
Depression affects 22 percent of Americans between the ages of eighteen and older each year. It is one of the most common medical problems in the United States. Depression affects both young and old, and women twice as much as men. Depression is an illness of the whole body. It affects the nervous system, moods, thoughts, and behavior. It also affects the way you eat and sleep, the way you feel about yourself, and the way you react to and think about the people and things around you. Symptoms of depression can last for weeks, months, or years. There are various types of depression, which vary in the number of symptoms, the severity, and persistence.
People with depression generally withdraw and hide from society, losing interest in things around them and becoming incapable of experiencing pleasure. Symptoms of depression include chronic fatigue, sleep disturbances, changes in appetite, headaches, backaches, digestive disorders, restlessness, irritability, quickness to anger, loss of interest or pleasure in hobbies, and feelings of worthlessness and inadequacy. Many people who are depressed think about death and consider suicide. Things appear bleak and time seems to pass slowly. Someone with depression can be chronically angry and irritable, sad and despairing, or display little or no emotion at all. Some people try to sleep off depression, while others do nothing but sit or lie around.
There are three main types of clinical depression: major depressive disorder, dysthmyic disorder, and bipolar depression. There are variations in the number of associated mental symptoms, severity, and persistence within these types. Dysthmic disorder is a chronic, but less severe type of depresses ion. It is characterized by milder, persistent symptoms that may last for years. It usually doesn’t interfere with everyday tasks. Bipolar disorders usually begin as depression but progress into alternating episodes of depression and mania, characterized by abnormally and persistently elevated mood, energy, restlessness, or irritability. Bipolar depression is commonly known as manic depression. It has other symptoms including inflated self-esteem, a decreased need for sleep, and increased talkativeness, racing thoughts, distractibility, physical agitation, and excessive risk-taking.
The causes of depression are not fully understood. However, it is assumed that there are most likely many and they are varied. Depression may be triggered by tension, stress, a traumatic life event, a hyper-stimulated immune system, chemical imbalances in the brain, thyroid disorders, nutritional deficiencies, poor diet, the consumption of sugar, mononucleosis, lack of exercise, endometriosis, any serious physical disorder, or even allergies. Whatever the factors that trigger it, depression starts with a disturbance in the part of the brain that governs moods. Most people can handle everyday stresses, with their bodies simply readjusting to these pressures. When stress is too great for a person and his or her adjustment mechanism is unresponsive, depression may be triggered.
The following vitamin nutrients are helpful for those who are suffering from depression: essential fatty acids, 5-HTP, L-tyrosine, SAMe, taurine, omega-3, vitamin B complex, zinc, choline, calcium, magnesium, chromium, GABA, lithium, NADH, and vitamin C with bioflavonoids. Additionally, the following herbs may be beneficial: lemon balm, ginger, ginkgo biloba, licorice root, oat straw, peppermint, Siberian ginseng, kava kava, and St. John’s wort.
Great vitamin supplements like the ones listed above are available at your local or internet health food store. When looking for natural vitamin supplements, always look for name brands to ensure that you receive a high quality and pure product.
*Statements contained herein have not been evaluated by the Food and Drug Administration. Vitamins, minerals, and herbs are not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.
April 05, 2009 01:40 PM
Attention deficit hyperactivity disorder (ADHD) is the newest name that has been given to a group of disorders of the central nervous system. With the long list of names this disorder has been given over the years, it is often confusing as to which criteria are for a diagnosis of ADHD or ADD. It is estimated that between 3 and 5 percent of children in the United States have ADHD, meaning that at least one child in a classroom of twenty-five to thirty children will have ADHD. There are three times as many boys diagnosed with ADHD, but the condition is increasingly being diagnosed in girls as well.
Although ADHD was primarily thought of as a childhood disorder, it can be found in adults as well. Experts have estimated that as many as 8 million adults may be affected, but 80 percent of them do not realize it. Some studies show that there is significant decline in ADHD symptoms as a person ages, while others estimate that between 30 and 70 percent of children with ADHD will carry some symptoms into adulthood. ADHD is a more complex disorder in adults, but it manifests itself into a problem with self-regulation. Without this self-control, an adult’s ability to do tasks is impaired. This condition can lead to marital conflicts, substance abuse, and financial problems. Infidelity is common because ADHD adults easily become bored with things, including spouses.
Factors that have been linked to the development of ADHD include heredity, anxiety, allergies, smoking during pregnancy, hyperinsulinemia, oxygen deprivation at birth, environmental stress or pollutants, artificial food additives, injury, infection, lead poisoning, and prenatal trauma. More emphasis has been placed on the role of diet in ADHD in recent years. Many people with these conditions react to certain preservatives, dyes, and salicylates in foods. These problems can cause the balance of chemistry in the brain to be thrown off, which produces undesirable changes in behavior. A low-protein diet may also be a contributing factor. Although a hotly debated topic for decades, studies have definitely shown that food additives do play a major role in hyperactivity.
Many researchers feel that ADHD is being over-diagnosed nowadays. It is difficult to accurately diagnose this condition because many of the symptoms appear in the normal, healthy children at many times during childhood. In fact, more than 60 percent of parents suspect that their child has ADHD at some point in their upbringing. What may merely be creativity or a high energy level can be diagnosed as ADHD. A diagnosis of ADHD should be made by a team of specialists who are experts in the disorder and it is wise to get a second opinion.
One should considered nutritional deficiencies and dietary measures for treating ADHD. The following nutrients are recommended: calcium, magnesium, GABA, a multivitamin and mineral complex, Omega-3 fish oil, Pycnogenol, Quercetin, SAMe, acetylcholine, DMAE, l-cysteine, phosphatidyl serine, vitamin C with bioflavonoids, and zinc. Additionally, the following herbs may be beneficial: ginkgo biloba, ginseng, mullein oil, valerian root, catnip, chamomile, gotu kola, hops, kava kava, lemon balm, licorice, lobelia, oats, passionflower, skullcap, St. John’s wort, thyme, and wood betony.
Creating a nutritionally sound diet for children and adults can go a long way to controlling ADHD and ADD in general. Reducing sugar intake and adding good quality food that hasn’t been over processed which removes the needed vitamins, minerals and phytonutrients we all need to live healthy lives. The above vitamins, minerals and herbs are suggested to be helpful for those suffering as well as those who aren’t, but always consult your health care provider before adding dietary supplements to ones diet while on prescription drugs. Quality vitamins can be found at your local or internet health food store.
*Statements contained herein have not been evaluated by the Food and Drug Administration. Vitamins, minerals, and herbs are not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.
August 26, 2008 04:58 PM
GABA is gama amino butyric acid, and is an inhibitory neurotransmitter that is essential for the proper function of your brain and the central nervous system, and has the effect of reducing excessive brain activity and promoting a state of calm.
For many people, the rush of daily life, with its problems, worries and external stimuli, can over-stimulate the brain to the extent that it can all seem too much for them. They feel anxious and overwhelmed, and wish that they could just go into a quiet corner to get away from it all. Most people have felt like that at some time, but the demands of life do not allow them that luxury. They just have to bear it and get on with life.
That is where GABA can come in. It can be used to bring your nervous system back to base, and make you feel more relaxed, calmer and more able to meet these challenges that life often throws at you. When you feel that you just can’t relax or concentrate on what you are doing, GABA can help you. If you look around you and everybody else seems OK, without apparently feeling the stress and irritability that you feel, and then perhaps your problem is due to a GABA deficiency. GABA is the principal inhibitory neurotransmitter in your brain, and a deficiency would certainly give you the symptoms that you are feeling. Let me explain why.
As your brain becomes excited, it can run out of control and needs some form of modification or inhibition to keep it acting as normal. Without this you would become increasingly more restless and irritable, and ultimately have seizures. GABA is not only the main inhibitor in your brain, but also helps in the production of endorphins that provide you with a sense of well being. That sense of calm you feel when endorphins are produced, for example during exercise or sexual intercourse, is commonly referred to as the ‘endorphin effect’.
GABA is at its highest concentration in specific areas of the brain, including the hypothalamus, the hippocampus and the central brain area, and is present in up to 40% of all synapses, the small gaps between neurons across which brain cells can communicate with each other.
It is produced during the Krebs or Citric Acid Cycle that is responsible for cell respiration or the production of energy from carbohydrates. It is synthesized from alpha-keto glutarate, which is produced just before the Succinyl Co-A stage of the Krebs Cycle in the brain. Vitamin B6 in involved in its metabolism, and a Vitamin B6 deficiency can lead to a deficiency in GABA that might result in seizures.
Basically GABA works by inhibiting the firing of neurons in your brain, and thus reducing general brain activity. The GABA receptor allows more chloride ion to enter the brain cell, thus helping to maintain the electrical charge within the cells. Bezodiazepines (e.g. diazepam) work by increasing the effectiveness of GABA in opening the chloride ion cells to allow more chloride ion to enter the neurons, and caffeine does the opposite, and inhibits this property of GABA. Thus diazepam works as a minor tranquilizer and caffeine as a stimulant.
Alcohol has a similar effect to the benzodiazepines, increasing the release of chloride into the neurons, and is the major way in which alcohol affects the brain. In fact, tolerance to drugs and withdrawal symptoms can be explained by the receptors adapting to the drug. They may increase in number, which means that more of the drug is needed to work on them, and they can become hypoactive in the event of the drug being withdrawn, that enhances the symptoms that the drug was intended to treat.
So basically, that is the way that GABA works. In simple terms it increases the flow of chloride electrolyte to the brain, and in so doing affects our mood. This effect is enhanced by prescription drugs such as Valium and Ativan, which are used by those that suffer the effects of a GABA deficiency. However, these drugs have side effects, not the least of which is dependency due to the GABA receptors becoming modified to suit the drug. There is a more natural way to overcome many stress problems and symptoms of mood swings.
Knowing what causes these symptoms, it makes sense to eat foods that stimulate the creation of neurotransmitters to replace those that are deficient. Since GABA is produced in the Krebs Cycle and complex carbohydrates produce glutamine that is an important part of that Cycle, and is also the precursor to GABA, then the consumption of such foods should in theory produce more GABA. In this case the theory works, and you should eat foods rich in complex carbohydrates such as whole grains, brown rice and oats as part of your diet.
Other foods that are high in glutamine or its precursors, glutamic acid and glutamate, include citrus fruits, beef liver, broccoli, halibut and lentils. A useful supplement to take is L-theanine, an amino acid found in green tea, and available in supplement form. L-theanine can calm your nerves while maintaining clarity of thought. In other words it calms you down, but doesn’t make you drowsy and allows you to enjoy your day with anxiety.
Your doctor can determine whether or not you have a neurotransmitter deficiency through a simple urine test, and might also test your saliva for hormone content. A GABA supplement might be indicated, and if so it other beneficial effects on your body other than its effect on your brain cells.
It improves your sleep cycles and promotes vivid dreaming, and can also have a positive effect on your blood pressure. It is also an effective pain killer, and can provide relief from such conditions as back pain and arthritis. Its stimulating effect on the anterior pituitary gland to secrete Human Growth Hormone might also be regarded as a benefit by many. Increasing the level of HGH in your blood can lead to fat loss and improved anabolic activity (increase in muscle tissue). This can be of benefit to older people whose level of HGH secretion has dropped off, and who find it more difficult to lose fat.
GABA is a substance that has many known benefits and no known side effects other than a slight tingling and increase in heart rate when the supplement is first used. It has a definite benefit for people to whom the world seems too hectic and overwhelming.
Wake up! This is National Sleep Awareness Week!
March 28, 2006 04:51 PM
We live in stressful times. Maybe that’s why more than 70 million Americans suffer from occasional sleeplessness, according to the National Institutes of health. Job related worries, marital and relation ship problems, even excitement about happy occasions—vacations or holidays—can all make it hard to fall asleep. Sleeplessness can also occur with jet lag, shift work, major schedule changes, even digestive problems.
Just turn on the TV and it’s obvious there are millions of customers looking for products to help them get a good nights sleep. And Source Naturals has an array of natural, effective sleep support supplements.
NightRest: This bio-aligned formula combines the powerful properties of melatonin and GABA with additional amino acids and herbs.
Melatonin: A neurohormone used as a restorative for occational sleeplessness.
Nutrasleep: a Unique herbal-nutrient blend, including skullcap, passion flower, valerian and chamomile.
Theanine Serene: Features L-Theanine, derived from Green tea, Plus GABA, Taurine, magnesium, and holy basil.
GABA: the chief inhibitory neurotransmitter in the brain, associated with mental states of calm and serenity.
L-Tryptophan: an essential amino acid, which helps support relaxation, restful sleep, and a positive outlook.
5-Htp: An intermediate to the conversion of tryptophan to serotonin, shown in clinical studies to support normal sleep cycles.
Benefits of Acetyl-L-Carnitine
February 12, 2006 01:55 PM
Theanine Serene™ with Relora® - to ease tension, improve relaxation
July 07, 2005 03:52 PM
NEW PRODUCT ANNOUNCEMENT
New and Improved!
Relora is a registered trademark of Next Pharmaceuticals.
Suggested Use: 2 tablets daily, or as recommended by your health care professional.
June 30, 2005 09:20 AM
Depression By Ellen J. Kamhi, Ph. D. with Dorie Greenblatt Depression is a widespread health imbalance that effects many people at some point in their lives, and may be caused by a multifaceted list of factors. Depression can be triggered by personal tragedy, loss of a loved one, or changes in life situations (even if they are positive!). Some of the less recognized causes of depression may involve diet, including over-consumption of sugar, artificial sweeteners, chemical flavorings and preservatives, insufficient nutrition and foods that causes an allergic or sensitivity reaction in an individual. Lack of exercise and not enough sunlight, (i.e. Seasonal Affective Disorder), may be implicated as well. It is essential that those suffering from severe depression seek professional care. Since depression can arise from many different sources and operate on multiple levels, it is helpful to remember that “true healing” requires one to explore and address the root cause(s), not just attempt to cover up the symptom. Proper nutrition is essential. B vitamins can be helpful, such as Nature’s Answer’s B-Stress with Herbs, along with other nutrients such as the amino acids, GABA (particularly for anxiety), Tyrosine and Phenylalanine. Regular exercise, and a nice relaxing bath in lavender oil and sea salt are also enjoyable aids for lifting one’s spirits.
Herbs can be useful in relieving the symptoms of mild to moderate depression. Nature’s Answer offers many high-quality, single herb and combination formulas (liquid or capsule) that feature ingredients well-known for balancing emotional mood. Relora®* features a patented propriety blend of two herbs, Magnolia (standardized to 1.5% honokiol (3.75mg)) and Phellodendron (standardized to 0.1% berberine (0.25mg)) which, when combined according to a particular method, may help reduce the negative effects of stress, a factor that leads to depression as well as “stress overeating”. When the body is under stress, it causes the release of specific “stress hormones” that influence mood and emotional well-being. Relora® is unique because its active plant constituents work on the body’s natural chemistry to re-establish a normal equilibrium of stress hormones, while enhancing feelings of relaxation and cheerful outlook.
Another powerful, “all-in-one” proprietary herbal blend formula from Nature’s Answer® is Mood Balance 2™ (alcohol free liquid, vegetarian capsule). Mood Balance 2™ contains key ingredients well-recognized for their beneficial actions on emotional health, including St. John’s Wort, California Spikenard, Gotu Kola, Skullcap and Eleuthero root**. This combination of ingredients can help “lift the spirits”. (Note that these herbs are also available from Nature’s Answer® as single herb formulas in concentrated liquid herbal extracts and/or vegetarian capsules; Kosher).
Key ingredients in Mood Balance 2™include:
St. John’s Wort (Hypericum perforatum), used for a range of nerve disorders and said to “chase away evil spirits.” Since 1996, it has become one of the most popular herbs in the US due to its use as a mild to moderate antidepressant. A number of current studies confirm its effectiveness, including a review in the British Medical Journal of 23 clinical trials, which reported that it worked nearly as well as the leading pharmaceuticals with far fewer side effects. Although more research is needed, it appears that the activity of St. John’s Wort is due to a variety of naturally occurring components, including Hypericin and Hyperforin. Nature’s Answer’s exclusive formula, Super St. John’s Wort (vegetarian capsule), is standardized to both 3.0% hyperforin and 0.3% hypericin. Gotu Kola (Centella asiatica), used for centuries in Ayurvedic medicine as a nerve tonic and to treat emotional upset, insomnia, stress, anxiety and memory problems. It is currently used along with meditation and yoga due to its abilities to both calm and energize nerves. Skullcap (Scutellaria lateriflora) has the double action of relaxing nervous tension while building the central nervous system. As a mild bitter it will also help stimulate digestion and help the liver. Eleuthero root** (Eleutherococcus senticosus) is an “adaptogen” that helps to balance the entire system. It gives strength and fortitude, especially when dealing with stress; so often a factor in depression.
References for Educational Purposes:
ALPHA GPC - Improves Mental Performance
June 28, 2005 06:21 PM
The quality of our life experience—and our ability to live life to the fullest—is a direct result of optimal brain function. Only a few years ago, nothing could be done to stem the tide of poor circulation, forgetfulness and “mental fog.” But neurological science exploration has identified a fundamental brain compound critical to attention, learning, memory, and even the higher cognitive functions of reasoning and intuition. Research confirms that L-alpha-glycerylphosphorylcholine (called Alpha-GPC for convenience) is crucial to neuronal function and structure. Derived from purified soy lecithin, Source Naturals ALPHA-GPC readily converts to acetylcholine in the brain, helping to maintain neuronal structure integrity. Source Naturals provides an easy and convenient means to profoundly impact the very nexus of our body and mind.
GPC Is Unique
No other nutritional compound comes close to GPC in its ability to boost critically important acetylcholine levels. Found in both the brain and the peripheral nervous system (including the nerve-muscle junctions), acetylcholine is a key nerve messenger molecule, or neurotransmitter. Aging brains are characterized by functional deficiencies in both acetylcholine and its cholinergic receptors. GPC is a highly bioavailable supplement that boosts acetylcholine levels to improve cognitive function. It is also a major choline reservoir, helping to protect the brain against damage from poor circulation and potentially toxic metabolites.
Deficiencies in acetylcholine can cause the body to break down phosphatidylcholine for its choline content, leading to the death of brain cells. Yet in controlled clinical trials of middle-aged subjects taking GPC, reaction time was enhanced and there was improved energy generation and electrical coordination in the brain. For older subjects, double-blind trials demonstrated that GPC had superior benefits over certain other brain nutrients for mental focus, recall, verbal fluency—a unique, marked overall enhancement of mental performance. GPC is an example of what the great Linus Pauling referred to as “orthomolecules,” that is, molecules that are “orthodox” or “correct” for the body. GPC excels as a protective nutraceutical for memory loss and mood enhancement. It protects cells of the brain (and other organs) from damage, shielding a range of important biomolecules against toxin build-up.
Extensive Clinical Testing
In clinical trials that involved more than 5,000 patients, GPC showed marked improvement in overall brain performance. Depending on the particular trial, 50-70 percent of the patients who received GPC had their mental functions improved to a degree “meaningful to life quality.” GPC has shown revitalizing effects on the declining brain, and preliminary evidence suggests GPC may act on the pituitary gland to partially restore its capacity to make vital for cell maintenance and longevity. Other unique brain features of GPC are its benefits for attention and recall in young healthy adults, and its superior bioavailability. GPC readily crosses the bloodbrain barrier to raise brain choline levels within a few hours following oral intake. GPC helps with body-mind integration by being a ready reservoir for acetylcholine. This neurotransmitter is ubiquitous in brain circuit maturation, expansion, renewal and repair, as well as in the “agility” or adjustments of the circuitry that occur during adult life. In addition, an animal study has shown that GPC increases the release of GABA (gamma-aminobutyric acid), the most important and abundant inhibitory neurotransmitter in the brain. It acts as a “balancer” for the brain and helps induce relaxation and sleep. Without sufficient GABA, neurons fire at random, unable to make sense of incoming signals. GABA helps minimize “neural noise,” making it easier to focus and concentrate.
Why you should take GPC:
Enhancer for Youthful Vitality
June 16, 2005 08:20 PM
NEW PRODUCT ANNOUNCEMENT
Enhancer for Youthful Vitality
Five tablets contain:
Suggested Use: 5 tablets before exercise and/or at bedtime with plenty of water at least two hours after the last meal. Discontinue use or reduce dosage if any of the following symptoms are present: nausea, excessive salivation, vomiting, diarrhea, muscle spasms, cramps, excessive urination, insomnia, headache, cardiac arrhythmias, high blood pressure, or changes in mood or emotional balance.
PREGNENOLONE - The Balancing Hormone
June 04, 2005 01:40 PM
Hormones are potent regulators of the most intricate biochemical functions involved in our metabolism, growth, development, emotion and behavior. For our bodies to function properly, our hormones must be in balance with one another. But aging, stress and environmental factors can contribute to hormonal imbalances, with serious impact on our well-being. Today, science has rediscovered a beneficial hormone with the capacity to reduce stress, fatigue and support mental alertness. This hormone is broad – spectrum in its influences - with the ability to balance the levels of other hormones in our bodies. Unfortunately, our production of this hormone declines as we grow older - suggesting the desirability of supplementation. Introducing: Source Naturals PREGNENOLONE.
A Wide Range of Beneficial Properties
Pregnenolone - a hormone produced from cholesterol in our adrenal glands, liver, skin, testicles, ovaries, and brain - was the subject of intense interest in the 1940’s. Some of the earliest studies, performed by well-known researcher Hans Selye, found it to be helpful in reducing stress and fatigue. Additional studies were conducted throughout the decade, with positive results. Pregnenolone supplementation was found to benefit people who were under excessive stress. It also was reported to support joint and tissue function and to contribute to skin elasticity. Pregnenolone is believed to affect stress levels through its influence on the adrenal glands, which produce more steroid hormones when people are under stress. Pregnenolone may also affect brain chemistry in beneficial ways. It has been found to inhibit the GABA receptors in brain cells - which may result in increased mental alertness. It may also stimulate the NMDA (N-methyl-D-aspartate) receptors, which play an important role in regulating synapses, thus influencing learning and memory.
Pregnenolone: The Unique Hormone
Much of the current interest in pregnenolone is related to its role as “the grandmother of all steroid hormones.” Pregnenolone is the starting point from which all steroid hormones are manufactured in our bodies. As a “hormone balancer,” it has the capacity to increase the levels of steroid hormones that are deficient in our bodies and to reduce the levels of excess circulating hormones. Some scientists believe pregnenolone is converted into other hormones only as they are needed by our bodies. The conversion of pregnenolone follows different pathways, depending upon cellular requirements. Pregnenolone may be converted into DHEA (dehydroepiandrosterone), which in turn can be changed into androgens (including testosterone), estrogens and other steroids; or, it may be converted into any or all of a chain of hormones including progesterone, corticosterone, and aldosterone. These characteristics make pregnenolone unique. Because cells may only convert pregnenolone into other hormones on an “as needed” basis, pregnenolone may correct imbalances in the levels of some hormones, without affecting others. This is a great advantage over steroid hormones like DHEA, which may create excess estrogen and testosterone. Pregnenolone is also distinctive because of the innumerable bodily activities it can influence. As a steroid hormone precursor, it is believed to be involved in every biochemical action exhibited by any steroid hormone. This means it may impact memory, mental alertness, stress responses, female reproductive cycles, the body’s natural defenses, and joint and tissue function. With such a wide spectrum of involvement, the potential uses of pregnenolone could be boundless. Source Naturals PREGNENOLONE is available in 10 mg sublinguals and tablets, as well as in 25 mg tablets. All potencies are sold in 60 and 120 tablet bottles.
Positive Thought - Balance Emotions and Mood...
June 04, 2005 01:34 PM
As modern life becomes increasingly stressful, people are seeking out natural products that promote calmness and relaxation. But unless your supplement addresses multiple body systems, a healthy positive outlook may be out of reach. POSITIVE THOUGHTS Bio-Aligned Formula supports the interrelated systems and functions involved with emotional balance: inhibitory, stimulating and balancing neurotransmitters, and energy metabolism. This comprehensive herbal-nutrient blend features St. John’s wort, which has been clinically shown to support a good mood.
A Bio-Aligned Formula™
POSITIVE THOUGHTS is designed to bring alignment to the multiple, interconnected systems that influence a positive mood. Here’s how:
Neurotransmitters are brain chemicals that aid in the process of nerve cell communication. Inhibitory neurotransmitters, such as GABA, reduce brain stimulation, helping to support a sense of relaxation and calm. The nerve cell membrane- stabilizing properties of taurine also support relaxation, as do the included herbs. In addition to supplying GABA and taurine, POSITIVE THOUGHTS supports inhibitory neuro-modulation with kava, lemon balm, valerian, and vitamin B-6.
Stimulating neurotransmitters help promote drive, ambition, alert mental functioning, and memory. They support a positive mental outlook by providing a feeling of energy and vitality. POSITIVE THOUGHTS supports stimulating neuromodulation with DMAE, L-phenylalanine, L-tyrosine, N-acetyl-L-tyrosine, and vitamins B-5 and B-6.
In our high-powered, stress-filled world, the balancing properties of St. John’s wort can help maintain a positive outlook and a sense of well-being. Studies have shown that St. John’s wort can help support a positive mood.
Acetylcholine is one of the most important neurotransmitters in the brain. It is vital for memory, cognitive function, focus, concentration, and muscle movement. POSITIVE THOUGHTS contains DMAE, vitamins B-1, B-5 and B-12, and pantothenic acid to support acetylcholine production.
The brain’s energy supports the vast electric, chemical, and structural processes that are the basis of a positive outlook. The brain uses 60% of the glucose used by the body at rest. Nutrients help convert glucose to the energy that the brain requires. They are also a component of many coenzymes needed for the synthesis of key neurotransmitters. POSITIVE THOUGHTS addresses energy metabolism with these nutrients: magnesium, manganese, zinc, vitamins B-1, B-2, B- 3, B-5, B-6, B-12 and C, biotin, and folic acid.
Strategies for WellnessSM: A Healthy Mood Plan
Lifestyle choices can help you maintain a positive attitude in response to the normal stresses of everyday life.
Neuro-Modulation—Inhibitory: GABA, Kava Kava, Lemon Balm, Taurine, Valerian, Vitamin B-6
Neuro-Modulation—Stimulating: DMAE, L-Phenylalanine, LTyrosine, N-Acetyl-L-Tyrosine, Vitamins B-5 & B-6
Neuro-Modulation—Balancing: St. John’s Wort
Acetylcholine Production: DMAE, Vitamins B-1, B-5 & B-12, Pantothenic Acid
Energy Metabolism: Magnesium, Manganese, Zinc, Vitamins B-1, B-2, B-3, B-5, B-6, B-12 & C, Biotin, Folic Acid
Mega Mind - re-align your body systems ...
June 03, 2005 05:24 PM
Aging and nutritional imbalances can disrupt the multiple body systems that affect healthy brain function. The result: cognitive symptoms* such as forgetfulness, inability to focus, and mental fatigue. MEGAMIND™ is a Bio-Aligned Formula™ that helps align multiple systems: neurotransmitter production, antioxidant defense, energy generation, circulation, and myelin sheath generation. Complementary Formulations Source Naturals can help keep your mind sharp and alert. Use MENTAL EDGE® Bio-Aligned Formula for foundational support, or MEGAMIND, when memory symptoms* are severe. HIGHER MINDTM is an additional Bio-Aligned choice. Take these formulas alone or as the core of a program that includes additional ingredients such as DHA (NEUROMINS®), GINKGO-24™, PHOSPHATIDYL SERINE, VINCAMINE, and VINPOCETINE.
In today’s complex world, we are bombarded with information. Our ability to process this massive input depends on how well we nourish the multiple body systems related to brain health. In addition, normal aging is associated with impairment of certain mental functions, according to the National Institute on Aging. The brain undergoes changes including functional decline in neurons important to learning, memory, planning, and other complex mental activities, as well as increased oxidative stress. In healthy people, these changes may result in varying degrees of age-related memory decline. Source Naturals can help, with a full line of cognitive support products.
Mental Edge®: Bio-Aligned Formula
MENTAL EDGE is a literal multivitamin for your brain. MENTAL EDGE supports production of neurotransmitters including acetylcholine, antioxidant defense, energy generation, stress response and myelin sheath generation. It features nutrients needed for production of neurotransmitters— chemical messengers in the brain’s communication system. One of the most important of these is acetylcholine, which is necessary for memory and muscle movement. MENTAL EDGE also contains antioxidants—vitamin C, ginkgo, DMAE, and zinc—to protect the neuron cell membranes where electrical signaling takes place. Adaptogenic herbs provide the brain with support and energy to deal with environmental stress. Energy-generating ingredients such as ginkgo and B-vitamins are vital to the high-powered functioning of your brain. Vitamins B-5 and B-12 are also important for formation of myelin, a substance that forms a protective insulating cover around certain nerve fibers and increases nerve impulse conduction.
MegaMind™: Bio-Aligned Formula When memory symptoms* are severe, you may need a formula with extraordinary cognitive support. MEGAMIND addresses many of the same body systems as MENTAL EDGE, but does so with megadoses of brain nutrients, such as L-pyroglutamic acid and vitamin B-1 for neurotransmitter production. It also adds bacopa and the inhibitory neurotransmitter GABA to support neurotransmitter production, and higher potency vitamin B-12 for myelin sheath generation. Like MENTAL EDGE, MEGAMIND supports energy generation and antioxidant defense. MEGAMIND augments basic support for the brain’s immense energy requirements with higher potency vitamin B-1, and with one of nutritional science’s most advanced, high-tech nutrients, alpha-lipoic acid. Lipoic acid is also an antioxidant, as are gotu kola and grape seed. MEGAMIND also supports circulation with ginkgo and gotu kola.
Mega Mind: Bio-Aligned Formula HIGHER MIND is another multi-system support formula, which features phosphatidyl serine, a structural component of nerve cell membranes, and the botanical vinpocetine. HIGHER MIND nourishes neurotransmitter production, cell membrane stability, energy generation, antioxidant defense and myelin sheath generation.
Neurotransmitter Production: Bacopa, GABA, L-Glutamine, L-Pyroglutamic Acid, Taurine, N-Acetyl L-Tyrosine, Manganese, Vitamins B-1 & B-6
Acetylcholine Production: Acetyl L-Carnitine, DMAE, Gotu Kola, L-Pyroglutamic Acid, Vitamin B-5
Myelin Sheath Generation: Vitamins B-5 & B-12
Energy Metabolism: Acetyl L-Carnitine, Ginkgo Biloba, L-Glutamine, alpha-Lipoic Acid, Calcium, Magnesium, Manganese, Potassium, Zinc, Vitamins B-1, B-2, B-3, B-5, B-6 & B-12, Biotin,Folic Acid
Circulation: Ginkgo Biloba, Gotu Kola
Antioxidant Defense: DMAE, Ginkgo Biloba, Gotu Kola, Grape Seed, alpha-Lipoic Acid, Zinc, Vitamin C
Complementary Cognitive Support Products
For additional support, you can supplement Source Naturals Bio-Aligned formulas with these single ingredient products: ACETYL L-CARNITINE and DMAE are both important to the synthesis of acetylcholine, a key neurotransmitter associated with higher cognitive functions, such as learning and memory. DHA (NEUROMINS®) is an omega-3 fatty acid that plays a significant role in cerebral development, especially during fetal development and infancy. GINKGO is renowned for promoting blood flow to the brain. Source Naturals GINKGO-24™ is a standardized concentration of Ginkgo biloba leaves, yielding 24% ginkgo flavone glycosides and 6% terpenes (the key constituents). PHOSPHATIDYL SERINE is necessary for the health of nerve cell membranes, where electrical signaling takes place. These membranes are critical to information processing. VINCAMINE, an alkaloid obtained from the periwinkle plant, supports cerebral metabolism by promoting blood flow and oxygen and glucose utilization. VINPOCETINE is a derivative of vincamine, shown in research studies to improve cognitive performance and alleviate the short-term memory loss that may accompany stress or aging.
Lifestyle Tips for Cognitive Health: A Strategy for Wellness SM
Eat Well: Recent research suggests that diets rich in beta-carotene and vitamins C and E help reduce memory problems, probably by lessening oxidative stress. And new animal research at the University of Toronto found that a high-fat diet slowed the ability of rats to learn new tasks. Use Your Brain: Learn a foreign language or new hobby, do crossword puzzles, read books, and cut back on TV. Scientists at Case Western found that people who were less mentally active in middle age were three times more likely to experience memory decline as they got older. Stay Active: Vigorous walking can improve mental processes in aging individuals, according to research. Aerobic exercise increases oxygenation and blood flow to the brain, resulting in improved memory, organization, and the ability to juggle intellectual tasks. Manage Stress: Longterm anxiety or depression can make a person more forgetful. Try to regulate stress, increase social contacts, and, if necessary, seek professional help. Get Organized: Make the most of your cognitive abilities, through the use of memory aids such as “to-do” lists, notes, or calendars.
Joint Response and Ultra Joint Response
June 02, 2005 01:01 PM
Many people are unaware of the multiple body systems involved with joint health. Source Naturals ULTRA JOINT RESPONSE™ is a Bio-Aligned Formula™ that goes deep to bring alignment to these multiple systems. It features structural building blocks, tissue production cofactors, and ingredients that aid the body’s mechanisms for soothing relief and antioxidant defense.
Joint Support Formulations
You can use ULTRA JOINT RESPONSE alone or as the core of your healthy joints program, complementing it with additional potencies and ingredients. These include: GLUCOSAMINE CHONDROITIN WITH MSM™, MSM Cream, SAME, CM COMPLEX™ Cetyl Myristoleate, and BROMELAIN. For muscle discomfort and fatigue, Source Naturals also offers you FIBRO-RESPONSE™ Bio-Aligned Formula.
ULTRA JOINT RESPONSE™: BIO-ALIGNED FORMULA
ULTRA JOINT RESPONSE uses scientifically researched ingredients and nutritive co-factors for a comprehensive approach to soothing, lubricating, rebuilding and aligning connective tissue, joints, tendons and ligaments. MSM dietary sulfur, glucosamine and sea cucumber provide structural building blocks that are necessary to help maintain the integrity of joints and connective tissue. Vitamins A, B-6 and C, zinc, manganese, and copper act as co-factors or parts of enzymes that play a role in connective tissue formation and maintenance. Various soothing herbs, rich in polysaccharides and other constituents, assist the body’s natural mechanisms for soothing relief. Finally, N-acetyl cysteine, grape seed, beta carotene, vitamin C, zinc, selenium, horse chestnut, turmeric, and quercetin support the body’s natural antioxidant response, thereby helping maintain the health and integrity of joints and tissues (specifically cell membranes).
GLUCOSAMINE CHONDROITIN WITH MSM: HOT RESEARCHED INGREDIENTS
For added support, Source Naturals offers you a formula that combines higher potencies of the most popular joint nutrients: glucosamine sulfate, chondroitin sulfate and MSM. GLUCOSAMINE CHONDROITIN COMPLEX WITH MSM provides the same amounts of chondroitin and glucosamine shown in recent research to support healthy joints—along with MSM, vitamin C, and molybdenum, for a more powerful product. Together, these ingredients promote joint, tendon and ligament flexibility and easy joint movement.
FIBRO-RESPONSE: BIO-ALIGNED FORMULA Dealing with the muscle discomfort that affects millions in our society requires more than alleviating fatigue. FIBRO-RESPONSE influences specific body systems and tissues involved in joint health and muscular metabolism. Malic acid and magnesium, supplied in the same amounts used in recent research, help support muscular energy production, along with coenzyme Q10, lipoic acid and B-complex vitamins. MSM, copper, manganese, molybdenum, zinc, vitamin C, and beta carotene support healthy connective tissue, which is essential for proper joint and muscle function. Key ingredients, including N-acetyl cysteine and silymarin aid the liver in eliminating toxic waste from blood and tissues. Ingredients including lipoic acid, selenium, N-acetyl cysteine, and coenzyme Q10 support antioxidant defense, thereby helping to maintain tissue integrity. And ginkgo and GABA are among the ingredients that support clear focus and stress reduction.
LIFESTYLE TIPS FOR HEALTHY JOINTS: A STRATEGY FOR WELLNESSSM Healthy lifestyle habits should be part of your individual strategy for joint wellness. Watch Your Weight: Population-based studies, including the well-known Framingham study, have consistently shown a link between obesity and challenges to joint health. Excess weight causes pressure on joints, and can speed the rate at which cartilage wears down. Eat Healthy: To support healthy joints, increase your intake of omega-3 fatty acids from salmon, sardines, flax seeds or flax oil, avoid excess protein intake, and replace animal with plant proteins when possible. You should also eat lots of organically grown fruits and vegetables, and eliminate polyunsaturated and hydrogenated oils. Exercise Regularly: Regular physical activity helps lubricate cartilage, strengthens muscles around joints, and promotes weight control. An exercise program geared to joint health includes stretching, mild weight training, and low-impact aerobics. Rest and Relaxation: Regularly scheduled rest gives your body time to recover and rebuild, allowing you to make the most of your exercise program. It’s important to know when to slow down. Supplementation: In addition to the formulas described above, Source Naturals offers a range of products that can supplement your strategy for joint wellness. These include the pineapple enzyme BROMELAIN; SAMe, a natural compound formed from the amino acid methionine, which has been found to support joint comfort and mobility; and CM COMPLEX™ Cetyl Myristoleate, a fatty acid ester shown in recent research to reduce joint discomfort.
Higher Mind - Smart Nutrients for the Performance of a Lifetime...
June 02, 2005 12:18 PM
Our adult years are the time to reap the fruit of an active, meaningful life – appreciated by family and friends who value our experience and knowledge. For some, however, their later years are clouded by a mental decline that erodes their capacity to enjoy life. More of us are becoming apprehensive about the future health of our minds. Will we still be able to communicate our needs as well as our wisdom? As science focuses its investigative might on the workings of the human brain, new findings suggest that it is possible to enjoy a vital, healthy brain and mind – well into old age. Based on compelling research, Source Naturals formulated HIGHER MIND. It contains the most important Neuroceuticals™ now recognized by nutrition scientists – including phosphatidyl serine, a natural nutrient that promotes cognitive function. The connection is clear: nourish your brain; enrich your life.
To have a healthy, well-functioning brain and nervous system, we need the correct nutrients. Our diets must provide the necessary raw materials for nerve cells to grow, for the synthesis of neurochemicals, and for the maintenance of nerve cell membranes. Nutritional deficiencies can alter the brain’s metabolism, which is expressed by changes in perception and thinking, behavior and mood.
Brain Cells – Issued at Birth
Before birth, neurons (nerve cells) are created at the amazing rate of 15 million per hour. As infants, we have over 100 billion neurons, but this is the most we will ever have because – unlike most other cells in our body – nerve cells do not reproduce. A different strategy is used to replace the neurons that are naturally lost throughout life: nerve cells repair themselves and grow by extending branches of nerve fibers called dendrites (from the Latin word for tree). These are the communication links with other neurons that form the circuitry of the brain. A single neuron may be in contact with up to a hundred thousand others! When the density of this fragile organic communication network decreases, we experience a corresponding decline in mental acuity.
Brain Cell Membranes
The membrane is the working surface of a cell. It needs to be strong yet flexible, so the cell can maintain its integrity and be able to move and change shape. The membrane regulates the flow of nutrients into the cell and the removal of waste, plus controls the passage of molecular messages from outside the cell to its interior. Membrane ion pumps use a third of the cell’s energy just to maintain the correct ratio of sodium to potassium. In neurons, a rapid exchange of sodium and potassium ions across the nerve membrane is responsible for their unique ability to generate the electrical impulses that are the basis of all communication in the nervous system. As cells age, their membranes become less fluid and more rigid. Key membrane molecules called phospholipids are crucial to the health of neuron membranes, allowing the brain to maintain its youthful quality. The phospholipids in HIGHER MIND – especially phosphatidyl serine and phosphatidyl choline – are essential nutritional supplements for the aging brain.
Phosphatidyl Serine – Key to Cognition
For the past decade, researchers have been investigating the role in brain health of a remarkable neuroceutical, phosphatidyl serine (PS). This key structural molecule is integral to the matrix of fats and proteins that compose cell membranes. Although PS is found in all the cells of the body, its highest concentration is in nerve cell membranes. PS is rarely found in the foods we eat, so the body has to synthesize it, but the process is energy- intensive and becomes less efficient with age. Consequently, our levels of PS tend to decline as we get older. PS taken as a dietary supplement is well-absorbed, readily reaching the brain, where it helps create more effective, well-structured nerve cell membranes. The positive effects of PS supplementation have been demonstrated by 23 clinical studies with over 1200 human subjects, ages 43 to 90. Consistent and statistically significant results have confirmed the value of PS in improving age-related cognitive decline, as well as in improving behavioral aspects such as apathy and withdrawal.1 A major study concluded that for one particular measurable parameter of higher mental functions, PS recipients achieved scores of persons roughly 12 years younger.2 Nerve Growth Factor (NGF) is one of the most important proteins the body makes. It enables neurons to extend dendrites out to other neurons, allowing the brain to maintain an effective communication network. In experiments, PS enhanced the production and reception of NGF, which tend to drop off radically with age.3 The effects of PS at the cellular level are manifest in the performance of the brain as a whole. Subjects taking PS showed increased levels of brain energy metabolism. This enhancement corresponded to higher performances on cognitive tests.4
The Chemistry of Thought
Science now understands the role of neurotransmitters in regulating the body’s complex network of behavior. Neurotransmitters are the chemicals used by neurons to communicate with each other. Activated by a neuron’s electrical impulse, neurotransmitters travel between nerve cells, where they excite or inhibit (in various degrees) the electrical impulse in neighboring cells. One of HIGHER MIND’S key strategies is to improve the brain’s ability to produce and use acetylcholine, a key excitatory neurotransmitter. Acetylcholine is essential for both the storage and recall of memory, and partly responsible for concentration and focus. It also plays a significant role in muscular coordination. Patients showing cognitive decline may exhibit reduced ability to synthesize and utilize acetylcholine.5 The chemical building blocks of acetylcholine and other neurotransmitters are called precursors. The most important one for acetylcholine is DMAE (dimethylaminoethanol). This natural substance is found in various fish, such as anchovies and sardines. Supplements of DMAE (and phosphatidyl choline) promote increased levels of choline in the brain. Acetylcholine is created when an acetyl group is attached to the choline molecule, with the help of choline acetyl transferase (CAT), a key brain enzyme. Acetyl L-carnitine is an amino acid that activates this enzyme. Acetyl L-carnitine may also help reduce lipofuscin deposits in the brain because of its involvement in the metabolism of fatty acids.6 Lipofuscin is composed of oxidized fats and proteins; the brown “age spots” on the back of an elderly person’s hand are made of lipofuscin. The amino acid L-pyroglutamic acid sensitizes the acetylcholine receptor sites on a neuron membrane. A given amount of acetylcholine will then have a larger, more powerful effect. Studies have shown that supplements of L-pyroglutamic acid seem to enhance the ability to focus, remember, and learn.
Total Nutrition for the Brain
The neurotransmitters dopamine and noradrenalin are critical to motor coordination, motivation, concentration, and alertness. Like acetylcholine, their production tends to decline with age. The precursors and activators of dopamine and noradrenalin included in HIGHER MIND are the amino acids N-Acetyl L-Tyrosine and DL-phenylalanine (DLPA), plus folic acid, vitamins B-3, B-6, and C. DLPA is also a precursor to PEA, a neuroamine that has a stimulating effect on the brain. Glutamine is an amino acid precursor to glutamic acid, a major excitatory neurotransmitter involved in mental activity and learning. Glutamine acts as an alternative fuel source for the brain when blood sugar levels are low. It also helps the brain dispose of waste ammonia, which is a natural result of protein breakdown but is irritating to neurons even at low levels. GABA is a dietary amino acid which is also an inhibitory neurotransmitter. GABA works to calm and balance the mind, enhancing mental focus. Along with taurine, these two relaxing neurotransmitters provide a balancing influence to the other, excitatory neurotransmitters. Taurine is found in brain tissue more than anywhere else in the body. It has antioxidant properties and serves as a nerve cell membrane stabilizer, preventing excessive or erratic electrical activity in the brain.
The Importance of Magnesium
Magnesium must be present in adequate amounts in the synaptic gaps between neurons or the neurons become hyper-reactive: causing noises to sound excessively loud and emotional reactions to be extreme. Magnesium also activates a key enzyme responsible for maintaining cellular sodium- potassium balance, which is absolutely essential to the electrical activity of nerve cells, as well as to the existence of the cell itself. (Cells would burst if the sodium-potassium ratio were wrong.) Magnesium also helps relax cerebral blood vessels and is important to the manufacture of ATP, the chief energy molecule of the brain. A buildup of aluminum has been found in the brains of some elderly. In 1989, the British medical journal Lancet published a study showing that drinking water with aluminum can increase the risk of damage by up to 50%. An abundant natural element, aluminum is now a common feature in our culture. It’s found in tap water, cookware, deodorants, beverage containers, baked goods, and of course as aluminum foil. In the brain, aluminum breaks down the structure of neurons – causing them to starve – by displacing magnesium from tubulin, a glycoprotein responsible for making microtubules. These tiny pipe-like structures within a neuron provide needed rigidity, as well as transport nutrients from the nucleus down the dendrites to the ends of the nerve cell. Magnesium malate is an excellent form of magnesium that ensures neurons receive this vital mineral.
B is for Brain Vitamins
HIGHER MIND also contains a high profile of B vitamins and other key nutrients that are often N A T U R A L S S O U R C E Strategies for Wellness SM ¤ lacking in older individuals. A deficiency in any of the B vitamins can alter nerve function and psychological well-being. Thiamine (B-1), known as the “nerve vitamin,” was first recognized because its deficiency caused beriberi, a degenerative nerve disease. Thiamine is part of the structure of nerve cell membranes and is important to the reparative process that neurons need to offset the stress of continual firing of the electrical impulse. Low amounts of thiamine can cause cell malnutrition in the hypothalamus, the brain’s memory center. 7 NAD and NADH, two coenzyme forms of Niacin (B-3), are the most plentiful coenzymes in the brain. They are essential to hundreds of enzymatic reactions, including ones that produce energy. NADH can stimulate the synthesis of key mood-elevating neurotransmitters. It is also one of the body’s most potent antioxidants. Pantothenic acid (B-5), cyanocobalamin (B-12), and folic acid are required to form the myelin sheath – the insulating covering of nerve fibers. A diet low in pantothenic acid has been shown to make test subjects emotionally upset, irritable, and depressed.7 A lack of B-12 can result in poor concentration and, in severe deficiencies, hallucinations. Pyridoxine (B-6) is precursor to over 60 enzymatic reactions and is involved in the synthesis of several neurotransmitters.
Brain cells almost exclusively burn glucose for their energy (other cells can also burn fat), and typically require 50% of all the glucose in the blood. Two B-like vitamins help in the utilization of glucose: PAK (pyridoxine alpha-ketoglutarate) may potentiate the effects of insulin and improve glucose utilization to the cells;8 Biotin is important for the transformation of glucose into energy in the brain. Lipoic acid and coenzyme Q10 are metabolic energizers that help produce ATP, the primary energy molecule in the body. Since the brain uses 20% of the body’s total energy supply, efficient ATP production is vital. Lipoic acid and CoQ10 are also powerful antioxidants that help regenerate other antioxidants in the body. The blood vessels feeding the brain become less efficient as we pass middle age. Since the brain depends on the bloodstream to deliver nutrients and oxygen and to remove waste, the quality of this blood flow is paramount to proper brain nutrition. Ginkgo biloba leaf extract has been shown in scientific studies to increase blood flow to the brain by helping vessels to dilate. It also promotes the smoothness and healthy integrity of blood vessel linings.
For the Life of Your Mind Without proper nutrition, the brain will deteriorate; therefore strategies are needed to both enhance current brain function and protect it throughout life. Based on the latest scientific findings, Source Naturals HIGHER MIND is formulated with neuroceuticals that support the mental functions that tend to decline with age. They give your brain the nourishment it needs to integrate perception, memory, and learning into a more comprehensive awareness – so you can excel for a lifetime.
Fibro Response - Feel your Vitality ...
June 02, 2005 09:56 AM
Millions of Americans, the majority of them women, are looking for a product to soothe muscles, relieve joints, support energy, and assist the liver’s natural detoxification process. Source Naturals FIBRO-RESPONSE is based on recent research into the physiological mechanisms involved in muscular metabolism. This research has given new hope to millions of people.
Fibro-Response: A Bio-Aligned Formulation™ FIBRO-RESPONSE is the latest in a series of formulas we refer to as Bio- Aligned Formulations. We evaluate the underlying causes of system imbalances, then design products that support alignment and harmony in your body’s interdependent systems and functions. These formulas provide targeted nutrition to help create Body Systems in Harmony™.
FIBRO-RESPONSE was designed to help bring harmony to the interdependent systems and functions that influence joint and muscle health. Our muscles need energy and oxygen to prevent them from becoming fatigued. FIBRO-RESPONSE soothes muscles and joints by supporting oxygen supply and energy production, provides powerful antioxidants for healthy joints and connective tissue, assists healthy liver function, and supports the nervous system and circulation. The ingredients were carefully selected to influence a range of body systems. Some were included for their combined effects with other ingredients; some play important roles in more than one body system.
Muscles and Energy Production: Our muscle cells are powered by adenosine triphosphate (ATP), a compound popularly referred to as “the energy molecule.” ATP supplies energy for all the body’s myriad physiological processes. To provide this chemical energy, the body generates and uses an amazing two to three pounds of ATP every day! ATP production occurs through a series of complex chemical reactions, including the Krebs cycle and the electron transport chain—and these energy production systems in turn require sufficient nutrients. Malic acid, a natural fruit acid that is also produced in our cells, and the essential mineral magnesium, are critical components of the energy production cycle in muscle cells. FIBRO-RESPONSE supplies both in the amounts used in recent scientific research. Additional ingredients that support energy production include coenzyme Q10, a coenzyme in the energy- producing pathways; manganese, which activates many metabolic enzymes; and copper, an important component of energy-producing enzymes. Pantothenic acid, and alpha-lipoic acid help form coenzyme A, a primary starting material for ATP production (pantothenic acid also supports the adrenal glands). Vitamins B-1, B-2, niacin and B-6 are all required for energy production.
Connective Tissue: Healthy connective tissue is essential for proper muscle function. MSM dietary sulfur supports the integrity of connective tissue and joints. MSM is included in FIBRO-RESPONSE in the amount used in recent joint health studies. Vitamins A and C, zinc, manganese, and copper all have important roles in supporting connective tissue. Liver Support: The liver is the largest and one of the most important body organs. Its vital functions include clearing the blood of toxins, and producing bile, which aids in fat digestion and carries waste products away from the liver. Liver detoxification is essential for muscle and joint comfort. Silymarin from milk thistle seeds is an important contributor to the support of healthy liver function. N-acetyl cysteine serves as a precursor to glutathione, a critical selenium-containing antioxidant produced in the liver, which binds to toxins to help remove them from the body. Alpha-lipoic acid and coenzyme Q10 play important roles in supporting liver health. This is partly because they are components of the body’s energy production process, and the liver demands a great deal of energy. FIBRORESPONSE also contains a classic Chinese herbal combination traditionally used to harmonize liver “chi” or “energy”: bupleurum, ginseng, pinellia, skullcap, ginger, cinnamon, and licorice. Their actions are complemented by the traditional Western herb dandelion.
Antioxidant Support: Antioxidants protect tissues and joints from highly destructive molecules called free radicals. Alpha-lipoic acid, termed the “ideal antioxidant,” complements the antioxidant activity of beta carotene and coenzyme Q10. Nacetyl cysteine, best known for supporting the liver, is also highly valued as an antoxidant. Zinc, selenium and copper support our natural defenses. Together, they provide a full armory of powerful antioxidants for joints and connective tissue.
Nervous System Support: Ginkgo biloba is renowned for promoting blood flow to the brain. This is crucial, since brain tissue is very metabolically active, accounting for 2% of our body weight, yet using 15% of our total energy supply. GABA is an inhibitory neurotransmitter that may regulate the nervous system and support clear focus. The herb skullcap, and vitamin B-6, add further support.
Taking Back Your Life: A Strategy for WellnessSM
Source Naturals’ expert formulators have created an experiential product that can make a difference in the way you feel. But supplementation is only part of the picture. Healthy lifestyle habits can redefine and empower your own strategy for wellness.
Rest and Relaxation. Deep, uninterrupted sleep is essential for energy and a healthy nervous system. Sleep 8 to 10 hours nightly and aim to finish meals two hours before retiring.
Exercise. Even if you feel exhausted and it hurts to move your muscles, you must keep moving. Start easy with nonimpact movement—yoga is an excellent beginning. Do some gentle stretches, followed by 5 to 10 minutes of blood-pumping activity (i.e. biking, stair-stepping, or dancing). Listen to your body: increase activity time only when it feels comfortable. Food and Nutrition. You’ve heard it before but now it’s time to pay attention: eat healthy. Avoid spicy, oily foods and choose light, mild alternatives. Go easy on sugar and incorporate whole grains into your diet. Enjoy steamed vegetables, alternate brown and white rice, and eat less red meat and more fish or soy. Reduce or eliminate milk products. Relax and take time to chew. And drink LOTS of water—it is essential for hydrating the body, flushing out wastes, and absorbing nutrients.
Breathing. Many people hold their breath unintentionally, often as a result of stress or anxiety. This can become a habit, reducing blood oxygen, interrupting the pumping mechanism of the diaphragm that helps circulation, and causing muscles to become tense. Breathe deeply and feel your lungs expand and fill. Notice how different you feel.
You have in your hand a powerful, comprehensive formula. Combined with a healthy lifestyle FIBRO-RESPONSE can help you make lasting changes that will empower you throughout life.
FIBRO-RESPONSE is available in bottles of 45, 90 and 180 tablets.
References Abraham, G. and J. Flechas. 1992. J. Nutritional Medicine (3): 49-59. American Medical Association, Encyclopedia of Medicine. New York: Random House, 1989. Garfinkel, L. and D. 1985. Magnesium (4): 60-72. Russell, I.J. et al. 1995. J. Rheumatology 22(5): 953-8.
Targeted Nutrition Muscle Cell Metabolism Malic Acid, Magnesium, CoQ10, Vitamin B-1, (ATP Production) Vitamin B-2, Vitamin B-3, Vitamin B-6, Manganese, Pantothenic Acid, Copper, alpha-Lipoic Acid. Connective Tissue MSM, Vitamin A, Vitamin C, Zinc, Manganese, Copper Liver Silymarin from Milk Thistle, N-Acetyl Cysteine, Ginkgo Biloba, Dandelion Root, Chinese Liver Blend (Bupleurum, Skullcap, Panax Ginseng, Pinellia Root, Ginger, Cinnamon, Licorice Root) Antioxidant Support N-Acetyl Cysteine, alpha-Lipoic Acid, Beta Carotene, CoQ10, Zinc, Selenium, Copper, Nervous System GABA, Skullcap, Ginkgo Biloba, Vitamin B-6.
Diet Metabo 7 -- It's all about Mood and Metabolism ...
June 01, 2005 12:08 PM
It’s incredibly difficult to stay committed to a weight loss program—to change the eating habits of a lifetime and resist “emotional overeating.” You need a weight loss program that helps you break the unhealthful cycle of dieting and losing— followed by bingeing and gaining back.
We can’t stop the Yo-Yo®, but we can give you a fighting chance.
DIET METABO-7 supports seven body systems related to successful weight loss, including cellular energy generation and metabolism, and neurotransmitter production to support calmness, drive and determination.
DIET METABO-7 SUPPORTS SEVEN BODY SYSTEMS
Your body is composed of complex interactive systems that work on many levels. Likewise, the nutrients in DIET METABO-7 target specific body systems and the connections between them. This full spectrum nutritional formula helps instill balance and harmony by addressing seven interrelated systems whose healthy function is necessary for successful dieting: the brain and nervous system, metabolic energy, liver, thyroid, blood sugar levels, adrenals and fluid balance.
MOOD MANAGEMENT: A POSITIVE ATTITUDE
DIET METABO-7 can help you change your habitual response to eating and start making healthy food choices. A key strategy involves the production of neurotransmitters, the brain chemicals that regulate your nervous system. When certain neurotransmitter levels are low in your brain, you may feel depressed. You crave simple carbohydrates and sugars from bread, pasta or candy— because when the brain is low in mood-enhancing neurotransmitters, it does whatever it can to increase them. It will cause you to crave those foods that produce the building blocks your body uses to raise those neurotransmitter levels. DIET METABO-7 provides specific vitamins and amino acids necessary for your brain to make norepinephrine, serotonin, dopamine and GABA, the major neurotransmitters that help regulate mood and attention, support clear focus and active calm, and affect drive and determination. Included are the amino acids tyrosine, glutamine, phenylalanine and GABA. For example, the brain uses phenylalanine and tyrosine to manufacture norepinephrine. Increased amounts of norepinephrine can block the drive to eat and may help provide a sense of well-being.
METABOLIC ACTIVATORS: HERBAL ENERGIZERS
To support a sustained reduction of body fat, it’s helpful to increase metabolism via exercise and herbal stimulation while lowering caloric intake by curbing appetite. High doses of stimulants, however, are counterproductive and can make you nervous and irritable. To avoid being overly stimulative, DIETMETABO-7 is formulated with appropriate amounts of herbal metabolic activators that promote calorie burning and suppress appetite.
Used since ancient times in India to support health, Sida cordifolia contains a profile of naturally occurring ephedrine alkaloids that act as stimulants to promote the metabolism of fat. This thermogenic effect is augmented by the natural caffeine contained in standardized extracts of green tea, yerba mate, and kola nut. Also included are specific B vitamins essential to the production of energy from the breakdown of fats and carbohydrates.
HELPING THE LIVER: DETOXIFICATION AND CIRCULATION
One of the most overworked organs is the liver, the body’s chief manufacturing and detoxification plant. It constantly regulates the levels of chemicals circulating throughout the bloodstream and plays a key role in breaking down fat and eliminating waste products. The amino acid N-acetyl cysteine is an antioxidant that strongly supports liver function. Your liver needs it to make glutathione, a crucial detoxifying substance used to remove harmful compounds from your bloodstream. Optimal metabolic energy depends on healthy circulation, especially while dieting, when the bloodstream is delivering excess waste products to the liver for removal. To help maintain a healthy circulatory system, DIET METABO-7 includes standardized extracts of ginkgo and horse chestnut. In use for centuries, these botanicals have been the subject of numerous chemical and pharmacological investigations.
THE THYROID: YOUR BODY’S THERMOSTAT
Your thyroid gland produces hormones that control how quickly you burn calories and use energy. Tyrosine is an amino acid building block of thyroid hormones. Low blood levels of tyrosine have been associated with the underproduction of thyroid hormones. Kelp and bladderwrack provide natural sources of iodine, the basic substance of thyroid hormones.
STABILIZING BLOOD SUGAR: CONTROLLING MOOD SWINGS An important strategy of DIET METABO-7 is to minimize the changes in blood sugar levels that can cause unwanted mood swings, which diminish your physical and mental energy. Chromium, an essential mineral, is important to carbohydrate and fat metabolism and tends to increase insulin efficiency. It helps stabilize blood sugar levels and keep you on an even keel.
DEALING WITH THE STRESS FACTOR
Dieting often adds more stress to your life, and stress hormones affect the mind and body in many ways. They disrupt liver function and blood sugar levels, which lowers energy production in the brain, adversely influencing mood and motivation. Because your adrenals need extra attention, DIET METABO-7 helps nourish these hardworking glands with pantothenic acid and ascorbic acid, both necessary for healthy adrenal function. Also, pantothenic acid provides additional support for energy generation during dieting.
Potassium is an essential mineral with many functions, including the transmission of electrical impulses in the brain. It works with sodium to control the body’s water balance. Dieting tends to deplete potassium levels in the body, therefore DIET METABO-7 replenishes this vital nutrient.
THE WEIGHT IS OVER
DIET METABO-7 provides necessary cofactors to balance body systems involved with healthy weight management. When used with the Maximum Metabolism Weight Loss Plan and exercise program, Source Naturals DIET METABO-7 may help you achieve your goal of a healthy and more vibrant life.
Calm Thoughts Kava - from Source Naturals
June 01, 2005 09:31 AM
Stress: it disturbs your serenity. Ultimately it takes a physical toll on your health. And it seems to be an unavoidable part of the hectic modern lifestyle. Source Naturals CALM THOUGHTS KAVA is a comprehensive formula designed to help you stay calm in the face of stress and anxiety—without sacrificing the clarity and focus you need to function effectively. CALM THOUGHTS is centered around a standardized extract of kava kava, the relaxing herb of choice for generations of South Pacific Islanders. But CALM THOUGHTS goes further, with soothing herbs and nutrients, rejuvenating ingredients and neurotransmitter support.
CALM THOUGHTS is centered around the renowned calmative kava kava. Used for generations by South Pacific Islanders, kava is known traditionally for its ability to help a person achieve a tranquil, meditative, yet focused state. Kava is an integral part of the spiritual and social fabric of Pacific Islanders’ life, used to help people relax and socialize. In Europe, where kava has been the subject of a number of double-blind, placebo-controlled clinical trials, science has confirmed its beneficial effects, and made kava a popular alternative for reducing stress. Those studies found reduced anxiety levels in individuals given standardized kava extracts. CALM THOUGHTS enhances kava’s calming properties with a number of supporting herbs. One of these is bacopa, known commonly as Brahmi in Indian herbalism and used extensively as a nervous system tonic. The formula also includes St. John’s wort, the most extensively studied herb in the market today, and the well-known calmatives lemon balm and valerian.
Several of the botanicals in CALM THOUGHTS are tonic herbs, helping to promote overall well-being. These include the adaptogens schizandra, ashwagandha and Siberian ginseng, all of which help the body deal with external stresses. Also featured are warming ginger, energizing licorice, and Ginkgo biloba, to promote circulation.
CALM THOUGHTS includes ingredients which influence brain neurotransmitters involved in the body’s reactions to stress. GABA is an inhibitory neurotransmitter which may have regulatory effects on the nervous system. Tyrosine is a precursor to the catecholamines norepinephrine and dopamine, which play an important role in mood balance and may have a role in emotional feelings and behavior. Dopamine is a precursor to norepinephrine, an “activating” type neurotransmitter which is involved with attention, arousal, the sleep-wake cycle, and appetite regulation.
CALM THOUGHTS contains a range of vitamins, minerals and amino acids. Calcium is essential for the healthy functioning of nerves and muscles. Magnesium is mildly relaxing to the muscles, while taurine modulates certain nerve impulses. Vitamins C and B-5 are important for healthy functioning of the adrenal glands and help in the body’s response to stress. Vitamin B-6 is important for healthy functioning of nerves and aids in the metabolism of tyrosine and taurine. For calmness with clarity and focus, choose Source Naturals CALM THOUGHTS KAVA. This groundbreaking formula is available in 45 and 90-tablet bottles.
May 24, 2005 10:05 AM
Abstract A dietary supplement for promoting healthy hormonal balance in adult human subjects, and especially in elderly subjects, that comprises a secretagogue for stimulating the release by the pituitary, and the conversion by to Insulin-Like G, in combination with 7-keto dehydroepiandosterone (7-keto DHEA). The dietary supplement also includes other interacting ingredients for delivering antioxidants for retarding damage at the cellular level caused by the presence of free radicals, and natural herbs for promoting physiological health.
Other References Jamieson, J. et al., "The Role of Intermediates as an Alternative to High Injections," American College for Advancement in Medicine, (Oct. 30, 1997).
What is claimed is:
GABA to improve memory ...
May 23, 2005 10:44 AM
Cerebral glutamate/GABA system to regulate learning and memory. Zhang, S. S.; Zhang, L.; Zhang, D. S. Pharmacol. Lab., Wenzhou Coll. Med., Wenzhou, Peop. Rep. China. Yaoxue Xuebao (1997), 32(8), 638-640. CODEN: YHHPAL ISSN: 0513-4870. Journal; General Review written in Chinese. CAN 131:111463 AN 1999:485466 CAPLUS
A review with 28 refs., on pharmacol. of stimulation and injury of learning and memory, discussing the involvement of neurotransmitters GABA, glutamate, and piracetam, with the emphasis of glutamate/GABA system in regulation and maintenance of learning and memory.
Study done in laboratory on male rats state that GABA increases memory and Learning
GABA involvement in memory consolidation: evidence from posttrial amino-oxyacetic acid. Katz, R. J.; Liebler, L. Ment. Health Res. Inst., Univ. Michigan Med. Cent., Ann Arbor, MI, USA. Psychopharmacology (Berlin, Germany) (1978), 56(2), 191-3. CODEN: PSCHDL ISSN: 0033-3158. Journal written in English. CAN 88:164675 AN 1978:164675 CAPLUS
In order to assess the possible effects of central GABA [56-12-2] activation on the consolidation of shock avoidance, the GABA inhibitor aminooxyacetic acid (I) [645-88-5] was administered posttrial to adult male rats. Learning was assessed over 9 widely spaced sessions of 20 trials each. I-treated animals showed learning within sessions and a lack of consolidation across sessions. Controls, on the other hand, showed learning both within and across sessions. This evidence agrees with previous reports suggesting GABA involvement in memory processes.