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Did you know that glutathione is not only great for liver health, but it also promotes beautiful, radiant skin?
Date:
December 07, 2023 12:12 PM
Did you know that glutathione is not only great for liver health, but it also promotes beautiful, radiant skin?Glutathione (GSH), often considered as an amino acid but actually a tripeptide, is an antioxidant primarily synthesized in the liver. Composed of cysteine, glutamic acid, and glycine, it plays a crucial role in the synthesis and repair of DNA and protein, as well as the synthesis of prostaglandins. With its involvement in various functions like amino acid transport, toxin and carcinogen metabolism, immune system function, prevention of oxidative cell damage, and activation of enzymes, it is undoubtedly the most important tripeptide in the body. While the benefits of supplementing with glutathione are numerous, two particularly compelling reasons are its positive impact on liver health and beautiful skin, which are the key focus of this article. However, before diving into the specifics of liver health and skin benefits, it's important to review the data on glutathione depletion and absorption. GSH depletion can occur due to various oxidative stressors such as radiation, v.infections, enviro toxins, household chemicals, heavy metals, surgery, inflammation, burns, septic shock, and dietary deficiencies of GSH precursors and enzyme cofactors. Additionally, research suggests that GSH levels tend to decline with age. The bioavailability of glutathione as a dietary supplement has encountered challenges in the past. Studies in the 1990s suggested that oral GSH might be inactivated by peptidases in the gut, as the levels of glutathione in the body did not seem to correlate with dietary intake, despite its presence in fruits, vegetables, and meats. Moreover, previous studies showed no significant increase in blood GSH levels when subjects were given high doses of 1,000-3,000 mg. As a result, alternative strategies like supplementation with NAC were used to boost GSH levels. In 2014, something interesting happened that changed the way we look at the bioavailability of GSH. A groundbreaking study published in the Journal of Agricultural and Food Chemistry shed new light on the old research. This study showed that GSH, when taken in its intact form as OPITAC, a yeast-derived glutathione by Kohjin/Mitsubishi, can actually be rapidly transported across intestinal epithelial cells. Once inside, it gets rapidly converted into oxidized glutathione (GSSG) and accumulates in red blood cells and the liver, with only a small presence in plasma. So, although the GSH was indeed absorbed, it didn't show up in blood plasma because it transformed into GSSG and stored in the red blood cells and the liver. The bottom line is, supplementing with GSH is an effective way to boost GSH levels in the body. This finding was further confirmed in another study that described how OPITAC, as a yeast-derived glutathione by Kohjin/Mitsubishi, is directly absorbed in its electrochemically reduced form in the intestine, then transported in the blood in bound forms, and eventually deposited into the liver in its reduced form. But here's where it gets even more significant. A six-month randomized, double-blinded, placebo-controlled trial involving 54 adults was conducted to investigate the effects of oral GSH supplementation (250 or 1,000 mg/day, as OPITAC glutathione, Kohjin/Mitsubishi) on GSH levels in various parts of the body, including blood, erythrocytes, plasma, lymphocytes, and exfoliated buccal mucosal cells. The results were astounding. After one, three, and six months, GSH levels in blood increased significantly compared to baseline in both dosage groups. At the six-month mark, GSH levels skyrocketed 30-35 percent in erythrocytes, plasma, and lymphocytes, and a mind-boggling 260 percent in buccal cells in the 1,000 mg group (P < 0.05). Even in the low-dose group, GSH levels in blood and erythrocytes increased by 17 and 29 percent, respectively (P < 0.05). This research clearly demonstrates that supplementation with GSH is not only effective for increasing GSH levels in the body but also for maintaining them. So, to sum it all up, the evidence speaks volumes - supplementing with GSH can have a profound impact on your body's GSH levels, and trust me, that's definitely a good thing! Liver HealthWhen it comes to our well-being, the liver is a true superhero. Let's dive into some fascinating details about this essential organ. Did you know that the liver is not only the largest reservoir of GSH (glutathione) but also a major site of GSH manufacture in the body? Pretty impressive, right? Special cells in the liver work tirelessly to synthesize GSH, which plays a crucial role in detoxification. Speaking of detoxification, the liver is a champion in this field. Its cells have sophisticated mechanisms to break down toxic substances, be it internal or external compounds. During the detoxification process, the liver attaches or conjugates the toxins to water-soluble substances. This attachment makes the toxic molecules more water-soluble, less harmful, and easier to eliminate via urine or bile. In fact, glutathione conjugation produces water-soluble mercaptates that are excreted via the kidneys, effectively detoxifying acetaminophen and nicotine. Isn't it amazing how this process helps our bodies get rid of harmful substances? But that's not all. Adequate levels of glutathione are crucial for the elimination of fat-soluble compounds, particularly heavy metals like mercury and lead. What's more, GSH serves as a cofactor for various peroxidase enzymes, aiding in the detoxification of peroxides generated from oxygen radical attacks on biological molecules. It also assists transhydrogenase enzymes in reducing oxidized centers on DNA, proteins, and other biomolecules. Talk about a multitasker! The practical significance of this liver superhero was demonstrated in a study involving workers exposed to lead. A group of five workers received GSH at 200 mg/day for 30 days, while five others served as the control group. The results were striking. The group receiving GSH showed a significant increase in ALA dehydratase activity (which is inhibited by lead) compared to the control group (p < 0.05). This indicates that GSH could be a valuable solution for treating patients with lead poisoning. So, let's take a moment to appreciate the remarkable liver and its incredible role in maintaining our health and well-being! Alcohol IntoxicationAlcohol consumption is widely recognized for its capability to induce hepatic steatosis, also known as fatty liver disease, and disrupt biomembranes due to hepatic lipid peroxidation. This can lead to various lifestyle-related diseases and even hepatic cirrhosis by diminishing hepatic physiological function. Nevertheless, animal studies have shown that hepatic damage caused by alcohol intoxication can be mitigated by glutathione (GSH), a powerful antioxidant found in cells. To further investigate the impact of GSH supplementation on the effects of alcohol intake, a human crossover comparative study was conducted. The study involved twenty healthy men and women who were grouped into three categories: placebo, 100 mg GSH (as OPITAC glutathione, Kohjin/Mitsubishi), and 30 mg curcumin. The study evaluated laboratory parameters, including breath alcohol concentration at different time intervals (20, 60, 120, and 180 minutes post-alcohol consumption) as measured by an alcohol checker. Additionally, subjective feelings were assessed through a questionnaire. During the study, all participants consumed whiskey in a quantity equal to their body weight multiplied by 1.25 mL, and were instructed to drink the entire sample within 10 minutes. The results revealed that the breath alcohol concentration in the group supplemented with GSH significantly decreased compared to the placebo and curcumin groups at 20 (p<0.01), 60 (p<0.01), 120 (p<0.05), and 180 (p<0.08) minutes post-consumption. Furthermore, the GSH group reported lower levels of "sleepiness," "headache," and "upset stomach" in the subjective feeling questionnaire. Importantly, the concentration of aspartate aminotransferase (AST), an indicator of alcohol-induced organ damage, was significantly lower in the GSH group after two months compared to the placebo group. The oral intake of GSH has demonstrated its effectiveness in reducing alcohol consumption-related stress and improving long-term hepatic function. These findings highlight the potential benefits of GSH supplementation in alleviating the detrimental effects of alcohol intoxication on the liver. Nonalcoholic fatty liver diseaseNonalcoholic fatty liver disease (NAFLD) is a condition characterized by the build-up of fat in the liver of individuals who consume little or no alcohol. Unfortunately, NAFLD is quite common, affecting nearly one-third of all American adults. Interestingly, it often presents without readily apparent signs or symptoms, sometimes resulting in complications, and can lead to liver inflammation and scarring as the fat accumulates. Additionally, NAFLD is typically associated with conditions such as insulin resistance, central obesity, reduced glucose tolerance, type-2 diabetes, and elevated triglyceride levels. Recognizing the substantial role glutathione (GSH) plays in phase 2 liver detoxification, a pilot trial was conducted to examine the therapeutic effects of GSH supplementation in patients with NAFLD. The trial included 29 individuals, and the patients were provided with daily oral supplementation of GSH at a dose of 300 mg (in the form of OPITAC glutathione, from Kohjin/Mitsubishi). The patients' clinical parameters were assessed before and after the GSH supplementation, and liver fat and fibrosis were quantified as well. The primary goal of the study was to determine any changes in alanine aminotransferase (ALT) levels. The results indicated a significant decrease in ALT levels following the GSH supplementation. Furthermore, triglycerides, non-esterified fatty acids, and ferritin levels also showed a reduction. This pilot study provides promising evidence for the potential therapeutic effects of oral glutathione administration, even at practical doses, in patients diagnosed with NAFLD. However, further investigation through large-scale clinical trials is necessary to validate its efficacy. In summary, NAFLD is a prevalent condition with potential serious consequences, but studies like the aforementioned pilot trial shed light on potential treatment options such as GSH supplementation. The findings demonstrate the need for continued research in order to provide more conclusive evidence and expand our understanding of NAFLD management. Beautiful SkinBy activating melanocytes in the skin, there is a notable increase in melanin formation, resulting in various blemishes such as freckles, pigmentation, and UV-induced skin spots, commonly known as age spots or liver spots. This is especially prominent after prolonged sun exposure and tanning. Age spots appear when melanin becomes concentrated or "clumped" in areas that have had years of frequent sun exposure. Luckily, there are materials like glutathione that can prevent or improve such pigmentation-related skin conditions. Another aspect to consider is skin pigmentation, wrinkles, and pores. In a study conducted with eight women in their 30s or early 40s, each supplemented with 100 mg/day of GSH (as OPITAC glutathione, Kohjin/Mitsubishi) for two months, their skin conditions were evaluated using the Robo Skin Analyzer. Several parameters were analyzed, including skin brightness, the amount and area of skin pigmentation, number of pores, and number of wrinkles under the eyes. It was observed that all subjects' skin brightness improved when measured on the second day of the study. Additionally, over the course of the two months, both the amount and area of skin pigmentation decreased, leading to an improvement in blemishes and pigmentation. Not only did glutathione exhibit a whitening effect, but it also reduced the number of wrinkles under the eyes and minimized pores. Furthermore, a randomized, double-blind, two-arm, placebo-controlled study was conducted with 60 otherwise healthy medical students. The purpose was to investigate whether supplementing with 500 mg of glutathione daily for four weeks would affect the skin melanin index compared to a placebo. Melanin indices were measured at six different sites on the body. The results demonstrated that melanin indices consistently decreased at all six sites in subjects who received glutathione after four weeks. The reductions were statistically significant compared to those who received the placebo at two sites: the right side of the face and the sun-exposed left forearm (p = 0.021 and 0.036, respectively). This improvement was likewise reflected in the reduction of UV spots. Importantly, both glutathione and placebo were well-tolerated. In conclusion, oral administration of glutathione leads to a lightening of skin color in the tested subjects. Skin LighteningSkin lightening is a process that is of interest to many individuals who seek to achieve a more even and radiant complexion. In recent studies, the use of a lozenge containing GSH 500 mg was explored as a means of skin lightening through an open-label, single-arm trial. The focus of this trial was to evaluate the buccal mucosa as a route for GSH administration and its potential in relation to skin lightening. It is worth noting that substances absorbed through the buccal route have the advantage of entering directly into the systemic circulation, effectively byPassing the gastrointestinal tract. The trial involved thirty Filipino females with Fitzpatrick skin types IV or V who received a daily glutathione-containing lozenge for eight weeks. The results from this trial demonstrated a significant decrease in melanin indices from baseline to endpoint. What is fascinating is that this visible change became evident in as little as two weeks. It is important to highlight that during this trial, there were no recorded serious adverse events, and the laboratory examination findings remained normal. Based on these findings, the researchers concluded that the lozenge containing glutathione was deemed safe and effective in lightening the skin of Filipino women. In addition to the aforementioned buccal route administration, another interesting approach that emerged from the studies is the topical application of GSH. A double-blind randomized clinical trial35 conducted in Yogyakarta, Indonesia, involved 74 healthy Indonesian women, with an average age of 33.3 ± 5.9 years, to explore the potential benefits of topical GSH. The trial subjects received supervised applications of facial wash twice a day, along with day cream containing sunscreen and night cream. The subjects were divided into three groups based on the active ingredients of the tested products, which included GSH (as OPITAC glutathione, Kohjin/Mitsubishi) at concentrations of 0.1 percent and 0.5 percent, and a control group without GSH. Throughout the trial, the effects of the tested products on skin color and pigmentation were measured using colorimetry with Chromameter Minolta for L. Compared to the baseline measurements, there were significant increases in lightness (L) detected as early as week 2 for the group using GSH at 0.1 percent concentration. Interestingly, this increase was significantly higher compared to the group using GSH at the higher concentration of 0.5 percent, as well as the group without GSH. It is important to note that hyperpigmented lesions also showed improvement, particularly in the group using GSH at 0.5 percent concentration, which displayed superiority compared to the other groups at week 8. In conclusion, the skin care products containing GSH at 0.1 percent and 0.5 percent concentrations were found to be effective in lightening facial skin. The findings from these studies shed light on the potential benefits of GSH in achieving skin lightening, either through buccal administration or topical application. It is worth noting that these studies focused on specific populations and more research is necessary to explore its effectiveness and safety across different skin types and ethnicities. In summary, the administration of glutathione, whether oral, buccal, or topical, has shown promising results in skin lightening and the improvement of complexion. Studies have demonstrated that glutathione not only enhances skin brightness but also reduces hyperpigmentation, wrinkles, and minimizes pores. Moreover, its effects have been evident in as little as two weeks, with a sustained impact over longer periods. These benefits were observed across a range of different skin types and ethnicities. However, it is important to highlight that these findings are based on specific populations, and more research needs to be conducted to confirm the consistency of these effects across a broader spectrum of skin types and ethnicities. The studies have also confirmed that the usage of glutathione is well-tolerated with no serious adverse effects reported.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6592) Congress Finally Frees Hemp From Jail: Big News For Farmers and CBDIndustry
Date:
January 06, 2019 04:20 PM
The Farm Act that was recently passed by Congress allows farmers across the nation to freely grow hemp as they please. Unfortunately, there are still restrictions set on the production of CBD products, which leaves a grey area in terms of what is acceptable and unacceptable. CBD oil is becoming more and more prevalent in treating psychological symptoms without the psychoactive effects that marijuana has. Industry leaders suspect that this bill passing is the first step in the CBD industry ultimately exploding. Key Takeaways:
"At any rate, the passing of the Farm Bill is sure to have implications on the growing CBD industry." Read more: https://www.thealternativedaily.com/congress-frees-hemp-from-jail-news-farmers-cbd-industry/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5937) Cannabis extract fights â??incurable formâ?? of Leukemia
Date:
June 20, 2018 04:44 PM
More and more researching is emerging surrounding the benefits of cannabis when it comes to its medicinal properties. A study was shown that involved a 14-year-old girl who was diagnosed with cancer. She had undergone several aggressive treatments such as chemotherapy, and her family wanted to seek out another alternative route. They started seeing a doctor who overlooked her consumption of cannabis for medicinal purposes, and it was shown to have quite a positive impact on her recovery. She ended up passing of causes unrelated to the cannabis use, but it doesn't take away from the success that medicinal marijuana helped her and her family achieve. Key Takeaways:
"There are plenty of anecdotal reports of the successful use of cannabis in treating cancer, but few cases occur under conventional medical supervision, and virtually none make it into a peer-reviewed biomedical journal as a case report." Read more: https://www.healthnutnews.com/cannabis-extract-fights-incurable-form-of-leukemia/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5636) The Surprising Anti-Aging Benefits of Fiber
Date:
February 19, 2018 03:59 PM
Fiber is one of those things we rarely we get enough of. Often we skip the whole grain food and go right to the processed. On the whole, we are eating 16 grams of fiber per day, but should be eating around 25 grams. Fiber is overall helpful in your diet. Not only does it help you feel full, but it has benefits to heart health and colon health. It can also help cut cholesterol by binding to it before passing out of the body. Key Takeaways:
"Technically, it isn’t a nutrient because it isn’t broken down and absorbed. But that’s what makes it so beneficial." Read more: https://www.consumerreports.org/diet-nutrition/anti-aging-benefits-of-fiber/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5534) Cannabis bills making headway in the Statehouse
Date:
January 27, 2018 03:59 PM
Indiana lawmakers are advancing a bill which would allow study of the use of medical cannabis in that state. Last Thursday, they voted 94-0 to advance the bill towards passage. Additionally, they passed a second bill which would allow for the possession and sale of hemp in the state. Simultaneously, a number of other bills are under consideration regarding the use of different types of oils derived from cannabis. Given the different positions and number of bills under review, it seems that it will be some time before there is complete legal clarity on this topic in Indiana. Key Takeaways:
"Thursday morning, a House committee, passed a bill legalizing the sale and possession of hemp by a vote of 12 to 0. State Rep. Jim Lucas, a Republican from Seymour, said his House Bill 1137 includes CBD oil." Read more: http://wane.com/2018/01/25/cannabis-bills-making-headway-in-the-statehouse/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5509) CBD and MS: Can Marijuana Treat Multiple Sclerosis?
Date:
April 26, 2017 03:59 PM
Although cannabis is still illegal on a federal level, more states have been passing laws to make this miracle plant available to those in medical need (and some even recreational). Cannabis has been shown to greatly help people who are suffering with MS by treating some of the symptoms (inflammation, pain, sleep deprivation, and even depression). It has also been noticed to have a preventive factor when it comes to protecting the eyesight of the patient. Key Takeaways:
"As the many benefits of marijuana continue to be discovered across the country, more and more states are deciding to legalize the plant for both recreational and medicinal use. One of the disorders that is considered treatable by medical marijuana is Multiple Sclerosis (MS)." Read more: http://www.marijuanaresources.com/cbd-and-ms-can-marijuana-treat-multiple-sclerosis/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4485) AVOID THESE 10 FOODS TO AVOID WORSE JOINT PAIN!!
Date:
February 14, 2017 10:19 AM
When you have arthritis, your body is in an inflammatory state. What you eat may not only increase inflammation, it can also set you up for other chronic conditions such as obesity, heart disease and diabetes. There are 8 food ingredients that may trigger more inflammation in your body, and most come from high fat and sugar content. https://www.youtube.com/watch?v=o9WeGDeS6kYKey Takeaways:
"Fat can make the pain of arthritis much worse."
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3939) Is Beta Carotene The Safe Vitamin A?
Date:
March 21, 2014 02:29 AM
What is beta carotene Beta Carotene is a capable pwerful antioxidant that is useful for the heart and circulatory. In the constitution, it is changed into Vitamin A for the support of solid skin, great vision, and a strong immune system. Vitamin An is fundamental for ordinary structure of epithelial cells that ensures the form from ecological defilement. Sources
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3071) Xylitol, a Healthy and Safe Sweetener.
Date:
March 12, 2014 09:05 PM
What is xylitol Xylitol is a comprehensively utilized regular sweetening operator that was initially uncovered by a German Chemist in the nineteenth century. The primary crude materials utilized for its assembling are birch trees and corn, however can moreover be processed from plums and berries. It is worth specifying that it is in addition commonly handled in little amounts by the human form. Xylitol is without a doubt not the most well known sugar substitute or nourishment added substance yet that doesn't imply that it isn't an essential one since it pushes various health profits. Researchers began investigating these profits once again a large portion of a century prior and more conceivable solid profits are continuously investigated today. Artificially it is a sugar liquor that has five carbon iotas in its compound structure and this structure is answerable for a large portion of its properties that make it gainful. As we specified, xylitol has various profits, yet the particular case that is best thought about is the way that it can avoid dental caries. Research discoveries are strong to the point, that this profit is undeniable. There are numerous instruments that are answerable for this valuable impact. One of them is that dissimilar to sugar and starchy sustenances it doesn't result in an abatement of the ph in the mouth, despite what might be expected it can help kill it. Acidic conditions in the oral pit are valuable for microorganisms like S. Mutans that are the primary driver of dental caries. Moreover, the acids processed can bring about harms to the tooth veneer that ensures our teeth. Other than securing tooth veneer, there are proof that propose it can additionally help restore it. Notwithstanding that, these microorganisms can't age xylitol to handle vitality so as to duplicate, then again sugar is their favored vitality source. At long last, xylitol can extraordinarily diminish the adherence of the organisms on the tooth surface and as a result their capacity to manufacture plaque. All the reasons above help xylitol's tooth day battling profits. It has been made clear that xylitol has various vital profits. On the other hand, it is paramount to note that it has several minor reactions also. The two fundamental symptoms that could be created by the utilization of xylitol are bloating and looseness of the bowels. These symptoms are created on the grounds that xylitol is ingested by inactive dispersion and happen assuming that somebody expends it above his laxation limit. It is likewise worth noting that the laxation limit can expand over the long run as the physique adjusts to the routine ingestion of xylitol. A couple of extra symptoms like unfavorable susceptibilities have been accounted for however they are not decently archived or affirmed via research information. At long last, most official associations, including the FDA have sanction it as a safe nourishment added substance for people.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3059) What is Xylitol?
Date:
February 09, 2014 08:50 AM
What is Xylitol? Xylitol is a 5-carbon Sugar alcoholic recognized even more particularly like a polyalcohol (polyol) and it has already been getting used because the 60's. You can find this within nourishments with regard to unique nutritional reasons as well as a number of without having Sugar goodies, candy, mints as well as biting down hard gums.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3012) Can Too Much Fiber Block Mineral Absorption ?
Date:
October 12, 2011 01:39 PM
Fiber Overview Fiber has always been known to be a helpful substance in many ways related to digestion and our bowel movements. In terms of how much is too much though we would need to look at first what fiber can do and how it works in the colon to have a broader point of view and to take all aspects into account before determining if too much fiber can cause health issues and specifically in this case, can cause a form of blockade for mineral absorption. What is Fiber and what does it do? Fiber, simply put is a substance that is found primarily in the outer layers of plants. Fiber is considered a carbohydrate and a special one at that because of its ability to stay intact even after Passing through our digestive system unlike other carbohydrates that gets broken down by food and used for energy. For better understanding let’s talk more about its importance. For one, it has the ability to influence our digestive process in so many ways. It’s most evident importance and function is how it is able to regulate digestion and virtually slow the process down. With this, it is able to allow us to feel full longer which will cause less appetite therefore affecting weight and in turn overall health. With the same process it slows glucose processing as well which will aid in sugar levels and also helps nourish the colon’s lining to keep it from damage and maintain its health. However in a more practical sense, it aids in our digestion because of its sponge like qualities. So if coupled with a good amount of water in the stomach it will aid and ease the stool and help bowel movements along. This is more known to many as a cleansing process which brings me back to the question, can it be too much and affect mineral absorption? Can too much affect absorption? A simple and most straight forward answer is “yes”. Yes it can, absolutely it can and “how?” you ask. As discussed above, one of the ways that fiber functions is aid with the cleansing process and the same sponge like qualities are the primary reason why it can affect mineral absorption in the colon. The reason why fiber is effective for cleansing is because it absorbs bacteria and any other toxin or harmful substances in the colon and flushes it out therefore promoting good health however it can’t filter through its absorption process and select only those toxins, rather it absorbs both good and bad substances, the good in this case being the minerals. So before it can be absorbed by the body, fiber already caused it to be excreted. But this does not mean you stop taking fiber, remember the key words here are “too much” and all we need to do to avoid any mineral deficiency is to follow the right amount, we can check with our doctor for best advice but most experts believe getting somewhere around 30 – 35g maybe too much but then again most Americans does not even come close to that with their regular diets.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2506) When Should Probiotics Be Taken?
Date:
October 04, 2011 02:00 PM
Probiotics are digestive bacteria which are naturally present in the gastric environment. This type of bacteria is necessary for the proper digestion of food as well as absorption of nutrients. Clinical studies have shown that the digestive tract must contain at least 10 to 15 % good bacteria to have a healthy digestion. In addition, trace amount of bad bacteria is also present inside the digestive tract. This is also important for digestion because these bacteria produce essential enzymes that aid digestion and absorption. The most popular probiotics is called Lactobacillus acidophilus. This kind of bacteria produces lactic acid inside the stomach when they reproduce. Lactic acid increases the acidity of the gastric environment thus enhancing digestion. The acidity of the digestive tract also helps protect the stomach and intestines from overgrowth of harmful microorganisms such as yeasts, spores, molds and bacteria such as Escherichia coli and Salmonella. The population of good bacteria in the digestive tract is depleted when the individual is on antibiotic therapy or under prolonged stress. Antibiotics are non – selective. This means that they do not only kill the harmful microorganisms but also the good ones. Good thing probiotics can be obtained from the diet such as yogurt, buttermilk, kefir and other fermented products. In addition, probiotics can also be provided by supplements. Therefore, when the person is to have an antibiotic therapy, the physician usually prescribes probiotic supplement to replenish the digestive tract with the killed good bacteria. Moreover, if probiotics are prescribed, another form of supplement may also be recommended to aid the activity of probiotic supplements. These are called prebiotics which are considered to be fibers, either soluble or insoluble. These prebiotics does not increase the number of good bacteria in the digestive tract. Prebiotics serve as food for good bacteria thus making them healthy and strong against bad bacteria. Sources of prebiotics include fruits, vegetables, legumes and grains. Other health benefits of probiotics are that it can enhance the health of the immune system and boost the intestinal barrier function. Probiotics also lessen the development of allergies to food and drugs. For lactose – intolerant individuals, yogurts with live and active cultures of lactobacillus acidophilus are recommended to relieve its disturbing symptoms. In addition, probiotics also has an anti – diarrheal property and at the same time helps in the regulation of normal bowel movement. A good probiotic supplement must have at least ten million live bacteria. Experts also stressed that the good bacteria contained in a supplement must be that of the Lactobacillus strains. This family of bacteria is the only considered group of good bacteria which is strong enough to reach the intestines, byPassing the acidic environment of the stomach. Another helpful tip on what a good probiotic supplement must be is that the product must be guaranteed organic. Organic probiotics ensure that the bacteria are in its natural and live state and have not been destroyed with heat and strong chemicals during processes. Experts also suggest that you must choose those probiotic supplements in which the source is from organic vegetables.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2475) Can Alpha GPC Really Help With Memory And Growth ?
Date:
September 29, 2011 11:52 AM
What Are The Benefits Of Alpha GPC? L-Alpha Glycerylphosphorylcholine, or abbreviated as Alpha GPC, is a natural compound which is choline in nature. It is considered to be an acetylcholine precursor which is now being studied as a treatment for the degenerative disease called Alzheimer’s disease. This chemical compound also has a parasympathomimetic property and is widely used as a nutritional supplement for enhancing memory and concentration. The other name of Alpha GPC is Choline Alfoscerate. Alpha GPC has the capacity to rapidly transport choline to the central nervous system by Passing through the blood - brain barrier. Alpha GPC can be extracted from highly distilled soy phospholipids such as lecithin. Inside the body, this chemical compound can be found in high quantity in neuronal membranes. Some of its benefits are: 1. IMPROVES ACETYLCHOLINE LEVEL. As mentioned earlier, Alpha GPC can cross the blood – brain barrier. Once inside the brain, it positively influences brain activity by enhancing the production of acetylcholine. Acetylcholine is a neurotransmitter which is responsible for improving the individual’s learning process. Acetylcholine acts on both the peripheral and central nervous system. In the former, this neurotransmitter functions as the main neurotransmitter in the autonomic nervous system. It is also involved in the contraction of body muscles. In the latter, acetylcholine acts as an anti – excitatory chemical in the cholinergic system. 2. MEMBRANE COMPONENT. Another health benefit of Alpha GPC is that it can effectively protect nerve cells thus improving the transmission of impulse. Aside from maintaining the integrity of the nerves and nerve cells, Alpha GPC also serves as a precursor of the phospholipids found on membranes. 3. INCREASE HUMAN GROWTH HORMONE. Studies on Alpha GPC have revealed that it can relatively influence the action of the body’s Growth Hormone – Releasing Hormone (GHrH), thus improving the release of growth hormones. In addition, it can also enhance the effects of human growth hormone especially among young individuals. 4. A MODALITY FOR DEMENTIA. Alpha GPC has been long studied for the treatment of senile dementia. Initial result of such studies revealed that patients supplemented with Alpha GPC showed improvement but on a smaller extent. Further studies are still being conducted so that efficacy and safety as well as the appropriate dosage will be determined. 5. INFLUENCES GABA. Studies reveal that Alpha GPC significantly increase the synthesis and release of Gamma Amino – Butyric Acid or GABA. Increased synthesis of GABA is also potentiated by atropine. GABA is considered as the principal inhibitory brain chemical among mammals. It has a significant role in controlling neuronal excitation all over the nervous system. Like acetylcholine, GABA is also one of the primary responsible chemicals for the control of muscle tone. Alpha GPC is formulated as supplement. It is available in 300 to 1,200 milligram oral supplements. Though it is generally safe, it is important that you should consult your doctor first before using this supplement. This would significantly avoid the occurrence of adverse effects and drug interactions. Appropriate dosage will also be determined by your doctor. Remember, any medication or supplement varies from person to person on its therapeutic and adverse effects.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2468) BPH
Date:
October 04, 2010 03:30 PM
Saw Palmetto Health benefitsSaw Palmetto has been used traditionally to treat a number of ailments, particularly in the medicine of Native Americans and Central Americans. It is specifically the fruit or berries of the plant that is used and its historical uses have included treating female infertility, menstrual pains and lactation problems. In men it has been used to reduce enlarged prostate glands and it is also used in the treatment of whooping cough, laryngitis and as an expectorant.Present-day saw palmetto benefits are generally focused on the treatment of benign prostatic hyperplasia (BPH), commonly known as an 'enlarged prostate, characterized by the development of large nodules in the area of the prostate around the urethra. This causes the urethra to be compressed, and the flow of urine to be partially blocked - in fact sometimes complete blockage occurs. Saw palmetto benefits in this respect are believed to lie in relaxation of the smooth muscle tissue and enable improvement in the Passing of urination. Native American medicine men used to carry a medicine bag of saw palmetto with them to treat these and related conditions.
Have you had your Saw Palmetto Berry Extract Today?
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2189) Colostrum and immunity
Date:
June 17, 2009 10:13 AM
In order to obtain a smooth running immune system, communication between cells is absolutely essential. To communicate between cells, the system uses hormone-like signal substances, which can often be found in colostrum. It has been found in studies that an immune response can literally be transferred from a donor to another recipient by simply feeding that person with an extract of leucocytes. This extract contained a factor that was capable of Passing on the donor’s immunity to the recipient. Scientists and researchers still do not know the exact constituents of colostrum, as colostrum extracts have been estimated to contain more than 200 individual compounds which each play a role in the communication process. Because an immature response within the immune system to an infection can take anywhere from ten days to two weeks to completely develop, colostrum is essential because it can reduce this delay in reaction time due to two factors it possesses: an inducer/helper function, and a suppressor function. The inducer function allows the body to develop a mature response in as little time as twenty-four hours. However, an overactive immune response to agents that are always present like pollens and the body’s own cells is not healthy. The suppression factor comes in here, as it helps to control hyper-reactive responses that commonly turn into allergies and autoimmune diseases. Together, all of this helps to keep the immune system and the body’s overall health in a balanced state. An infant’s first food is usually a mother’s milk, which is full of nutrient-rich colostrum. Colostrum contains valuable components which help the immune system to communicate and pass information between the cells. There are agents passed through colostrum that are not species-specific, meaning that they are equally effective in one species as they are in another. Additionally, this means that these agents generally do not cause allergies. Colostrum and its derivatives can be used for many conditions including herpes, hepatitis, chronic fatigue syndrome, candidiasis, cancer, type I diabetes, intestinal injury, autism, rheumatoid arthritis, AIDS, and the Epstein-Barr virus. Herpes, which is a commonly found disease in today’s world that manifests itself in recurrent outbreaks which are characterized by sores and other skin lesions. Colostrum has been found to decrease the frequency of herpes outbreaks, as well as shortening the duration of any outbreak that is experienced. Agents found within colostrum are specifically programmed to fight the hepatitis viruses and are even able to prevent the onset of hepatitis. Because colostrum and its immune agents are able to effectively help the body combat a variety of pathogens, it is also believed that colostrum can help to fight conditions like chronic candidiasis. Cancer may be prevented and fought with the use of colostrum and its various agents. Diabetes, which is one of the world’s most widespread and debilitating disorder, is increasingly associated with dysfunction of the immune system. Research has shown that colostrum and its compounds may have the ability to reverse diabetes. Colostrum has also been proven in studies to reverse the effects of autism on a child to the extent that the child can return to a mainstream school and participate in social activities. The Epstein-Barr virus, which is associated with symptoms including extreme fatigue and headaches, may be affected by colostrum, as studies have shown the total remission of symptoms in patients with this virus. Colostrum is an amazing substance. Fortunately, it can be found at your local or internet health food store in capsule or tablet forms for easy consumption. Always purchase name brands like Source Naturals, Kal, and Now Foods to ensure quality and purity of the product you purchase.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2019) Stop Constipation
Date:
March 29, 2009 10:08 AM
Constipation occurs when one has difficulty Passing stools, or infrequently passes hard, dry stools. This is the result of food moving extremely slowly through the large intestine. From time to time, most people experience constipation. However, lifestyle changes and better eating habits can help to relieve the symptoms and prevent recurrences. Constipation usually results from insufficient amounts of fiber and fluids in the diet. Fiber can be found in plant foods like whole grains, fruits, and vegetables. Fiber that is water-soluble takes on a soft texture and is helpful in softening the stools. Insoluble fiber goes through the large intestine unchanged and is helpful in adding bulk to the stools to stimulate bowel contractions. Other factors that can cause constipation include inadequate exercise, advanced age, muscle disorders, structural abnormalities, bowel diseases, neurogenic disorders, and a poor diet, especially a heavy consumption of junk food. Constipation can also be a side effect of iron supplements and some drugs, like painkillers and antidepressants. It is also common during pregnancy. High levels of calcium and low levels of thyroid hormone can also lead to constipation. Those with kidney failure are also prone to having problems with constipation. Constipation is often caused by dehydration in older individuals, with depression being a factor in people of any age. Some medications, like cough syrups, pain medications that contain codeine, antidepressants, iron supplements, blood pressure and heart medicines, calcium supplements, and some antihistamines can also cause constipation. A small percentage of people with spinal injuries and other similar problems have constipation because the nerves that usually regulate bowel movement have been damaged or destroyed. A condition referred to as Hirshsprung’s disease makes the normal excretion of feces impossible because the nerves inside the bowel are missing. The nerve cells in the colon can also be damaged by long-term use of laxatives, which makes constipation inevitable. A thrombosed hemorrhoid, anal fissure, or a pocket of infection at the anus can create a spasm of pain that is strong enough to contract the muscles and prevent the evacuation of stools. Constipation can cause a variety of other ailments such as appendicitis, bad breath, body odor, coated tongue, depression, diverticulitis, fatigue, gas, headaches, hemorrhoids, hernia, indigestion, insomnia, mal-absorption syndrome, obesity, and varicose veins. It may even be involved in the development of other serious diseases like bowel cancer. It is important to have regular bowel movements in order to remove toxins from the body. Toxins from bowel bacteria and undigested food particles play a part in the development of diabetes mellitus, meningitis, myasthenia gravis, thyroid disease, candidiasis, chronic gas and bloating, migraines, fatigue, and ulcerative colitis. People can have bowel movements as infrequently as three times a week and still not be constipated, but there are some health practitioners that believe that it is important to have a bowel movement every day. The following nutrients are very helpful in dealing with and preventing constipation: garlic, vitamin C with bioflavonoids, apple pectin, chlorophyll liquid, essential fatty acids, a multi-enzyme complex, a multivitamin and mineral complex, vitamin B complex, vitamin D3, vitamin E. Additionally, the following herbs are also beneficial: alfalfa extract, fennel seed, aloe vera, ginger, milk thistle, triphala, cascara sagrada, goldenseal, rhubarb root, senna leaves, and yerba mate. Adding a good fiber supplement as well as the above mentioned supplements can help one stop constipation and start normal bowel movements again. Natural fiber, vitamins, and herbs are available at your local or internet health food store. Look for name brands such as Source Naturals, Solaray, Kal, Planetary Formulas, and Natures Plus to ensure quality and safely of all your natural supplement needs.
*Statements contained herein have not been evaluated by the Food and Drug Administration. Vitamins, herbs, and fibers are not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1984) Inositol And Choline
Date:
December 11, 2008 12:19 PM
Inositol is a member of the vitamin B complex family, being referred to as vitamin B8, but is not strictly a vitamin because it is biosynthesized in your body. Vitamins are essential substances that are not manufactured by your natural biochemistry, and must be taken in your diet. However, to all intents and purposes it works like a member of the vitamin B family. The main function of myo-inositol (the commonest isomer of inositol) is in the health of cell membranes, particularly those that comprise the marrow, eyes, intestines and the brain. Without proper regulation of the cell membrane, the cell cannot function effectively. Some of its effects include healthy hair and controlling estrogen levels. It is also believed to help to reduce cholesterol levels in the blood. A deficiency will result in hair loss, eczema, increased blood cholesterol levels and eye abnormalities. You might also suffer constipation, although this is not as serious a condition as those preceding. It is present at highest levels in the heart and brain, which indicates where it is mostly used, although it also helps the liver to break down fats and enables the nerves and muscles to operate as they should. Those that are depressed are frequently found to have low inositol levels in their spinal fluid, so it is believed to play a part in that condition. It is known that the substance takes part in the function of the neurotransmitter serotonin, which is known to play a part in depression, and initial signs are that its use in the treatment of depression could be effective. Neurotransmitters are responsible for Passing messages across the gap (synapses) between nerve cells, their messages being decoded by the neuroreceptors. A healthy nervous system depends on healthy neurotransmitters. For these reasons, inositol has also been tried on other conditions of the nervous system. These include bipolar disorder, bulimia, panic disorder, obsessive compulsive disorder and attention deficit disorder. So far, results have been inconclusive as to its effectiveness, but it is early days yet and field tests are continuing. A test carried out in Beersheva, Israel, in 1997, found that treatment with inositol produced significant improvement in the depression of 28 patients after four weeks on the Hamilton Depression Scale1, and 21 patients tested with panic disorder (with and without agoraphobia) showed significant improvements in their condition, including agoraphobia. Results on 13 patients with obsessive compulsive disorder also showed significant improvement. These were all double-blind tests. However, not all tests have been so conclusive, and a study on 42 people with sever depression who did not respond to conventional antidepressant, also failed to respond when inositol was added to their medication.2 Results are therefore not conclusive. Four hundred people took part in a double-blind test that indicated a possible improvement in the symptoms of polycystic ovary syndrome when treated with inositol 3,4 and another that inositol treatment on patients taking lithium could help reduce the symptoms of psoriasis, a skin condition believed to be caused by a reaction of the immune system and nerves.5 The supplement has also been found to be just as effective as Luvox (fluvoxamine – similar to Prozac) after four weeks treatment. Although these results are good, they are inconclusive, and more data is need before any indisputable conclusions can be drawn. However, treatment with inositol might be worth considering if conventional treatment for these conditions has been unsuccessful. The most common natural form of inositol is myo-inositol, an isomer of cyclohehexanehexol, a carbocyclic polyol that form the structural basis for secondary messengers in the cells of eukaryotes. A secondary messenger system is one whereby a signaling molecule is released in response to a signal from a primary messenger such as a neuroreceptor, which then activates certain intracellular proteins known as effector proteins that exert a response from the cell. An example is cAMP (cyclic adenosine monophosphate) that is a secondary messenger that activates protein kinases and allows them to phosphorylated proteins. Eukaryotes are organisms that contain cells composed of complex components contained within a cellular membrane, and that also contain a nucleus. Examples are fungi, plants and all animals. Examples of non eukaryotes include the bacteria family. It is frequently recommended that inositol is most effective when taken with an equal amount of choline, although this might be due to the fact that when inositol deficiency is detected, choline is also frequently deficient. Both are vitamin B family like, and both are lipotropic, in that they aid the breakdown of fats in the body. It is not clear whether this is true or not, but taking both would certainly not harm you, and might be of great benefit. Inositol is not essential, because it can be obtained from beans, nuts, seeds, whole grains, cantaloupe, brewer’s yeast, liver and vegetables. Bacteria in the gut also act on the phytic acid (inositol hexaphosphate) contained in citrus fruits to form inositol. However, be careful if you drink a lot of coffee. It destroys inositol, and if you are taking the supplement medicinally, steer clear of coffee during your period of treatment because it will lose its effect. Excessive coffee drinking can also result in a general depletion of inositol from your diet, and hence a deficiency. In such a case you are advised to take a supplement, preferably along with choline that might also be deficient. Although there have been no adverse side effects reported, no specific longer term safety studies have been carried out on inositol. Because of the way it works, inositol should be avoided by people with liver or kidney disease, and also by expectant or nursing women. It should be avoided by young children until safety tests have been carried out, and it is believed that it can cause manic effects in those suffering bipolar disorder. Other than for these specific cases, trials with many times the average daily intake of the substance, it currently appears safe to take inositol as a long-term supplement. However, as with all such supplements intended for specific disorders, you should seek the advice of your physician. References: 1. Levine J: Ministry of Health Mental Health Center, Faculty of Health Sciences, Ben Gurion University of the Negev,Beersheva, Israel ur Neuropsychopharmacol, 1997 May, 7:2, 147-55 2. Nemets B, Mishory A, Levine J, et al. Inositol addition does not improve depression in SSRI treatment failures. J Neural Transm. 1999;106:795-798. 3. Gerli S, Mignosa M, Di Renzo GC. Effects of inositol on ovarian function and metabolic factors in women with PCOS: a randomized double blind placebo-controlled trial. Eur Rev Med Pharmacol Sci. 2003;7:151-9. 4. Gerli S, Papaleo E, Ferrari A, et al. Randomized, double-blind, placebo-controlled trial: effects of myo-inositol on ovarian function and metabolic factors in women with PCOS. Eur Rev Med Pharmacol Sci. 2007;11:347-354.
5. Allan SJ, Kavanagh GM, Herd RM, et al. The effect of inositol supplements on the psoriasis of patients taking lithium: arandomized, placebo-controlled trial. Br J Dermatol. 2004;150:966-969.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1948) What Is Fiber?
Date:
July 21, 2008 02:56 PM
Fiber often has been called roughage, as it technically is a food component that is undigested and processed through the gastrointestinal tract. Since it readily absorbs water, it helps to add to the bulk that is required in order to form a good bowel movement. Fiber is often described as a complex carbohydrate, which consists of the polysaccharide and lignin substance that often gives structure to the cell of a plant and is the portion of plant food that is not digested. Fiber which is insoluble has the capability of Passing through the intestines intact and unchanged. Unlike fats, carbohydrates, and proteins, fiber does not give the body nutrients or fuel for energy, and has no caloric value. Dietary fiber can only be found in plant components including vegetables, fruits, and whole grains. Primarily, there are only two types of fiber: soluble and insoluble, with some foods containing both types. Soluble fiber is eventually digested in the large intestine, causing it to have limited bulking power. Soluble fibers dissolve in water and have often been linked to helping prevent blood sugar highs and lows, helping to lower blood cholesterol, lowering the risk of heart disease, helping to control high blood pressure, and encouraging friendly bacteria growth. Soluble fiber can be found in pectin, lignin, gums, mucilages, and other sources such as psyllium, beans, apples, pears, and oat bran. Soluble fiber doesn’t usually seem like fiber. It is digestible and, when broken down, it creates a gel as it absorbs water in the intestinal tract. It does not bulk the stool to the extent of insoluble fiber, but it does slow down the rate at which food is digested. Soluble fiber is found in vegetables, particularly onions, bulbs, leeks, and asparagus, and also fruits, including dried varieties. Insoluble fiber remains undigested for the most part and promotes a faster stool transit time. Insoluble fiber can keep the bowel clean and operative and also help to bind dangerous toxins and hormones in order to promote better excretion. Insoluble fiber also fosters regularity in the body, contributes to better digestion, prevents constipation, and helps to lower the risk of bowel disease. Insoluble fiber is primarily composed of cellulose and hemicelulose. Cellulose is a non-digestible form of fiber, found in outer portions of vegetables and fruits. Bran or seed covering of whole grains is another type of insoluble fiber. Hemicellulose fibers remain unchanged and absorb water as they travel the digestive tract. They increase stool bulk and transit time, preventing constipation and conditions like hemorrhoids. Stalks, stems, peels, and fruit and vegetable skins are all made up of insoluble fiber. However, the insoluble fiber content of fruits is actually found in its flesh and stringy membranes, rather than its peelings. The average person needs a good variety of foods that contribute to at least 35 grams of dietary fiber in our diet daily. Most foods contain both types of fiber, but the ones that are most fiber rich are not usually the ones that we commonly eat. Whole grain cereal, raw fruits and vegetables, split peas, beans, lentils, millet, and barley are the best sources of fiber. Unfortunately, statistics have shown that most of us only get 9 grams of fiber each day, if we are lucky.
Finally, fiber has the ability to increase fecal bulk by retaining water, decrease stool transit time, keep blood sugar levels more stable, lower blood serum and liver cholesterol, help prevent weight gain by slowing the rate of digestion and absorption and controlling hunger, expediting the removal of dangerous toxins, binding with bile salts to help decrease the risk of gallbladder disease and certain types of cancer, and creating the presence of healthier intestinal bacteria.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1840) ChewyZymes
Date:
June 05, 2008 04:15 PM
Positioning purpose: As the body’s biological workforce, enzymes are fundamental to healthy digestion and metabolism, energy production, and immune system balance. Unfortunately, very few people actually consume an adequate amount of enzymes from their day-to-day modern diets. As the body ages, it produces fewer enzymes with each Passing year. Over time, the system-wide effects of insufficient enzymes can manifest in a number of unsuspected ways. Hormone and neurotransmitter production can decline, wounds may not heal as fast, fatigue can become a more regular occurrence, digestion may suffer, and the body may become more susceptible to infection. Product Description: ChewyZymes™ utilizes National Enzyme’s BioCore system, a broad spectrum digestive enzyme formulation in a natural berry-flavored, vegetarian chewable tablet that is perfectly suitable for both adults and children. It is designed to support improved digestion of meals. Digestive enzymes are essential to the body’s absorption and full use of food. The enzymes in this product are non-GMO. They have been proven in a controlled laboratory study by TNO Nutrition and Foods Research to have efficacy throughout the entire pH range of the digestive system and to not be degraded by acid in the stomach.* Each serving (2 lozenges) is equal to 1 capsule of our popular Optimal Digestive System. Ingredients: Ideal Users: Ideal for healthy adults and children who may benefit from additional enzymes in their diet. Complementary Products: Consider taking this product with NOW® BerryDophilus, Kid Vits, or Chewable C.
Recommended Use: Adults: Chew 2 lozenges before a meal. Children: Chew 1 lozenge before a meal. Supporting Science * These statements have not been evaluated by the FDA. This product is not intended to diagnose, prevent, treat or cure any disease.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1811) Increase Absorption Of Your Discount Vitamins With Bioperine
Date:
November 02, 2007 04:54 PM
In order to understand how you increase absorption of your discount vitamins with Bioperine, it is necessary to understand the metabolic process of thermogenesis. First, however, let’s have a look at what Bioperine is and where it comes from. Bioperine is obtained from the fruit of Piper nigrum L (black pepper) or Piper longum L (long pepper) of which it is a patented standardized extract. These peppers contain the alkaloid piperine, and the extract contains 95% piperine. The plants are grown in the ideal damp soil in regions of Southern India where the earth is rich in nutrients. The barriers are harvested just before ripening, and then dried in the hot sun before the extraction process is started. Piperine has many uses from flavoring to fly killer, but people have been using it for centuries to heal wounds though this is apparently unconnected with the use to which the extract is put. It has recently been found to help increase the absorption of a number of discount vitamins and minerals, including Vitamin B, beta-carotene, and selenium, by increasing the thermogenic activity of the body. Thermogenesis is one of the metabolic processes of the body that takes place within our cells whereby glucose is converted to energy, but at an accelerated metabolic rate. It is the rise in the metabolic rate that is referred to as thermogenesis. When you eat food, or take supplements, the metabolism increases above the normal rate, the amount of increase depending upon the type on nutrient taken. Fats will increase your metabolism at a lower rate than proteins will, for example, since more energy is needed to break down proteins than for fats. Another substance that stimulates thermogenesis is piperine. It does so by utilizing the biochemistry of the body so that the chemicals needed for thermogenesis are made available. Piperine triggers the release of compounds known as catecholamines, hormones that in turn stimulate the thermogenetic process. However, this occurs over a short period of time, so the nutrients that are needed should be present in the gut as well since the window of absorption is very narrow. The substance also modifies the epithelial cell wall of the intestine to make it easier for the nutrients to be absorbed into the bloodstream, and it also gives amino acids a kick to get moving to the cells in which they are required. Bioperine, then, not only sets off the metabolic changes that demand vitamins and other nutrients and enzymes, but also improves the conditions in your intestines so that these nutrients can more easily get to where they are needed. Basically, what Bioperine does is to cause the intestinal wall to become more permeable to nutrients, so that vitamins and drugs are not degraded when Passing through the intestinal wall to the bloodstream. This improves digestion and absorption of minerals and vitamins, in addition to protein supplements frequently used in weight loss diets. Bioperine starts by generating a need for nutrition and then increase the bioavailability of the nutrients provided to meet that need. However, due to the short window of absorption that piperine generates, the vitamins and minerals you want absorbed should be co-administered with the Bioperine so that they are in place ready to be absorbed at exactly the right time. There have been several studies carried on the efficiency with which piperine achieves this. The absorption of three different types of nutrients has been measured with and without Bioperine. These were beta-carotene, a fat soluble vitamin, vitamin B-6, a water soluble vitamin, and also a mineral, selenium which was provided as selenomethionine. The absorption of these by the digestive system was measured by detecting them before and after in the blood, and were found to increase considerably when taken along with Bioperine, but not so with the control group without it. Measured increases were a 60% increase in beta-carotene, similar to that of vitamin B-6, and was 30% in selenium. The tests used a 5 mg dose of the Bioperine. Other studies have indicated an increase in the absorption of Coenzyme Q-10 of between 30% - 200%. This is the only piperine based product that has been patented for its effect in increasing the absorption of nutrients into the body, and also the only piperine based product to undergo such tests in the U.S. to substantiate its claims and prove its safety for use. The black pepper itself is a common household spice, and has been used in India for its medicinal properties for centuries. It is mentioned in the practice of Ayurveda and its concentration on the function of the digestive tract in human health. Many of its formulas contain black pepper amongst their ingredients. The bioavailability of nutrients is a significant factor in the health of any specific population, and the exponents of Ayurveda overcame this problem, by chance or design, six millennia ago. It has been demonstrated time and time again that diet is not the factor of importance in nutrition, but how much of that diet is absorbed through the intestines. This is yet another example of the medicines of our ancestors being shown to have a solid scientific basis, and perhaps we should pay more attention to those others that are disregarded by modern science. It could be that we have only scratched the surface of understanding human metabolism and biochemistry, and that there is much left to learn. Ancient wisdom should never be disregarded. Bioperine is also available in many supplement mixtures so that it is taken at the same time as the relevant vitamins and minerals. The recommended dosage is from 1 mg – 5 mg from 2 – 3 times daily. It takes around 2 – 5 mg of Bioperine to provide sufficient enhancement of absorption of the nutrients that are taken with it. Keep in mind that the nutrients are best taken at the same time, and that taking the extract itself will simple increase the absorption of any nutrients that are in the intestine at that time. Bioperine can be purchased at your local or internet vitamin store.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1615) Omega-3 Relieves Depression in Some Individuals
Date:
November 02, 2007 03:27 PM
Omega-3 oils contain fatty acids that are known as essential fatty acids because they cannot be manufactured in your body but have to be taken in your diet. They provide many benefits to your body, and are also believed to relieve depression in some individuals. First, however, an overview of the more conventional benefits of omega-3 oils. Obtainable in your diet from oily fish such as mackerel, herring, salmon and the like, omega-3 fatty acids play an important part in your normal growth and development, and are also crucial to normal brain function. They can reduce inflammation and protect you from heart disease and some cancers. Studies have shown the fatty acids to be particularly concentrated in the brain and to be important for cognitive processes and memory. The effects of omega 3 fish oils on the brain are well documented, and they are known to be effective treatments in some cases of bipolar and schizophrenia. It is believed that they could also be used as a treatment in other disorders such as attention deficit disorder and dyslexia, but there is as yet no evidence that this is the case. Omega-3 fatty acids reduce the so-called ‘bad’ low density lipoprotein (LDL) cholesterol levels and increase the high density lipoproteins (HDL) that take the cholesterol back to the liver for destruction. The end result is a reduction in the cholesterol content of the blood that can be deposited on the artery walls and promote atherosclerosis. Diets high in omega-3 fatty acids appear to lower blood pressure in those suffering from hypertension, and so reduce their chances of heart attacks and strokes. Omega 3 oils are also natural inflammatories, and help prevent conditions involving inflammation such as arthritis, asthma and menstrual cramps. They appear to help the immune system to fight these conditions and reduce the inflammation and its causes. They are also important in the formation of prostaglandins that are responsible for the regulation of important functions such as blood pressure, blood clotting and immune response. They are hormone-like substances and also control the synthesis in the body of other hormones. If the balance of fatty acids in the diet is not right, then the subsequent imbalance in prostaglandin and hormone production can lead to disease. It is in its effect on depression and mood, however, that has surprised many in the medical, profession. Ethyl-eicosapentaenoate, known as ethyl EPA, is a constituent of omega-3 fish oil and many studies have demonstrated that this substance helps cases of depression and related disorders. However, are people justified in turning to ethyl EPA to help them be cured of this condition? In one study involving 20 people, six out of ten people given the supplement displayed significantly reduced symptoms of depression after four weeks. The effects were noticed as early as two weeks and many of the depression symptoms, such as worthlessness and insomnia, had improved after three weeks. This conformed with the results of many other studies that have been carried out world wide. In Scotland, a number of patients were studied who had failed to respond to traditional antidepressant drugs. Of the seventy patients involved in the trial, all of the patients who were treated with EPA displayed significant improvements in all the symptoms of their depression after four weeks whereas those with the placebo showed no improvement. Of the two main components of omega-3 fish oil, EPA and docosahexaenoic acid (DHA), only the EPA has this property, and the EPA works best alone when the DHA has been extracted. Studies and tests have indicated that the DHA appears to be important for the brain’s structure, but the EPA for its function, hence the reason for the ineffectiveness of the former in relieving depression which is a function of the brain rather connected to its structure. In fact, depressed people have been found to be deficient in EPA in comparison to those not suffering from the condition. The original idea for this originated with the late Dr. Horribin who was pioneer in researching the effects of lipids on the biochemistry of the brain as far back as the 1970s. Since then the world-wide research has confirmed his theory. However, the reason why this theory works in practice is not yet understood. It has been established that a diet rich in trans fats can unfavorably affect the hormones in the brain that stabilize mood, possibly due to the fats slowing down the system of messaging within the brain. This kind of effect can cause depression. This is likely due to the slowing down of the messages Passing between the synapses. Brain cells communicate by means of chemicals that cross the synapses, or small gaps between the individual cells. They are not directly connected like normal electrical circuits. It has been theorized that the EPA speeds up the passage of these messages between neurotransmitters and neuroreceptors. Other theories have also been promoted, such as that the EPA has properties of its own that cure depression by another route altogether. A possible clue could be in the findings of one study on a man aged 21 years old whose brain was scanned before and after EPA treatment. The result showed in increase in the mass of brain cells after the treatment. This was contrary to the belief that brain cells could neither be generated nor grown once a person reaches maturity. An individual suffering depression who would like to treat themselves with EPA would have to buy a lot of oily fish since high doses are needed for this level of therapy. However, it is found in high concentrations in a few supplements available on the market, and when choosing you must use the highest grade of EPA you can get, with as low a DHA content as you can find. There is little doubt now; however, that the EPA content of omega-3 relieves depression in some individuals, although more work is needed to prove without doubt that it is effective with all forms of depression.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1613) Aloe Vera’s Healing Properties Recognized 1500 years before Christ
Date:
April 21, 2007 01:53 PM
Fifteen centuries before the birth of Christ, Egyptian writings acclaimed the miracle plant we know as Aloe Vera, even then referred to as an ancient cure. Cleopatra, Alexander the Great and Aristotle were fans of this strange succulent prized for its soothing, healing and analgesic ability. Indians in central and South America used it to treat burns, kidney and bladder infections, dysentery, stomach and intestinal disorders. The pulp of the plant has been used to reduce swelling and pain from injuries, while in Mexico its used to treat arthritis and gout. For many years people have kept aloe plants around for emergency burns. We took a good look at this fascinating botanical wonder. Of the 200 plus varieties, we quickly found that only five or six fit the enzymatic structure for the cosmetic and so-called “medicinal properties” mentioned. Then while we were studying these succulents in their natural desert setting, we observed the roadrunner bird drinking the juice of the aloe vera, Passing up many aloe plants to get to a particular variety, Aloe Barbadensis Miller. We then studied acre after acre and found the roadrunner “peck marks” only on one particular species. The other aloe plants were untouched. In studying this species of plant more carefully, our Houston lab found that, indeed it had much different gel than other aloes. The products now labeled as Georges “Always Active” Aloe are exclusively from Aloe Barbadensis Miller, the Roadrunners’ choice. George Warren, an Independent research chemist in Houston, Texus developed the special processing method that prevents the spoilage without diminishing the essential properties of the Aloe Vera plant. This new method completely eliminates the anthraquinones that are mildly toxic and can cause irritation to the digestive tract. Aloins are also removed, which give a bitter taste (and the Greenish color) to Aloe Vera juices along with the starches and sugars from the polysaccharide molecular chain and thus, George “Always Active” Aloe requires no refrigeration, and will not spoil in its natural state. This method adds no water, no preservatives and no chemicals of any kind. The finished product looks and tastes like spring water.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1524) Peppermint Oil for IBS
Date:
March 24, 2007 11:01 AM
Irritable bowel syndrome (IBS) is a painful and frequently frustrating disorder of the intestines that’s often difficult to treat. Fortunately, there are scientifically studied natural products that effectively reduce the distressing symptoms of IBS. Q. What is IBS? A. IBS causes crampy pain, gassiness, bloating, and alterations in bowel habits. IBS is termed a functional disorder, because when the colon is examined, there is no visible sign of disease. While IBS causes significant pain and distress, no actual damage is occurring in the intestines. There is a wide variability in IBS. Symptoms may be mild and fairly well tolerated. Or, the pain, discomfort, and bowel dysfunction may be disabling, limiting social interactions, employment, or travel.
While some individuals with IBS have diarrhea (frequent, loose stools with an urgent need to move the bowels), others have constipation (hard, infrequent stools that are difficult to pass). And, still others may experience both. Individuals with IBS also may have painful abdominal cramps and feel an urgent need to move the bowels, but are unable to do so. A. The small intestine receives digestive material from the stomach and delivers it to the large intestine (colon). About two quarts (2,000 ml) of digestive material enter the colon from the small intestine every day. The colon absorbs water and salts from the material, which is progressively moved through the colon. This progressive movement continues until most of the fluid and salts are absorbed into the body and stool is formed. The stool passes to the left side of the colon, where it is stored until a bowel movement occurs. Because researchers haven’t been able to find actual damage in the colon, it once was suggested that individuals with IBS have emotional problems or are overly susceptible to stress. While stress may cause symptoms of IBS to intensify, it doesn’t cause the condition. Recent study has determined the colon muscle of an individual with IBS spasms after only mild stimulation. It’s thought the symptoms of IBS are produced by hyperactivity of the intestines. In other words, the intestines of individuals with IBS are more reactive to stressors and diet than usual. Almost everyone has experienced abdominal queasiness in response to everyday stress or certain foods. This may result in a brief bout of diarrhea or an upset stomach. However, this response is exaggerated in individuals with IBS. Q. How prevalent is IBS?
A. IBS is very common. In fact, it’s one of the most frequent problems seen by family physicians. It’s the most common disorder diagnosed by gastroenterologists (physicians specializing in the treatment of digestive disorders). The overall prevalence rates range from 10% to 20% of the general population in most industrialized countries. As a result, the pain and disabling symptoms associated with IBS result in significant socioeconomic costs, as wall as reduction in quality of life for many individuals. A. Normal bowel function varies from person to person. Some people move their bowels daily, while others may only have two to three stools a week. A normal bowel movement is soft, formed, and is easily passed without cramping or pain. IBS, however, causes abdominal cramps and pain, which are often severe and disabling. Bowel movements may be irregular and alternate between diarrhea and constipation. The diarrhea may be quite loose and watery. Mucous may be passed. There is often much straining, urgency, and feeling of incomplete evacuation (emptying). Abdominal bloating and Passing of gas is common. Nausea, lack of appetite, heartburn, and belching may also be present. Sleep may be disrupted resulting in fatigue and lack of energy. Understandably, persons with IBS often feel anxious and depressed. Diagnosis of IBS is usually based on the continuous presence or recurrence of these symptoms for at least three months. Other intestinal conditions must be ruled out. These include Chron’s disease, ulcerative colitis, inflammatory bowel disease, colon cancer, inflammatory conditions of the stomach or pancreas, ulcers, infectious disease, or gastroesphageal reflux disease. Q. Are there clinically demonstrated natural alternatives to the over-the-counter drugs prescribed by my doctor? A. Yes, both enteric-coated peppermint oil and clown’s mustard (in combination with other herbs) have significant scientific research behind them. Both have been demonstrated to benefit individuals with IBS. Q. What is clown’s mustard and what does it do? A. The scientific name for clown’s mustard is Iberis amara. Other names for this herb are wild candytuft and bitter candytuft. Clown’s mustard is a white-flowering plant from Spain, where it grows in dry soil on hillsides and in cornfields. It is also grown in Britain, France, and the United States. Iberis amara is a member of the Brassicaceae family. Iberis refers to its place of origin, the Iberian Peninsula. Amara means bitter. The key components of clown’s mustard are glycosides and flavonoids that have specific actions on gastrointestinal tract tone. Q. Is there scientific evidence that clown’s mustard benefits people with IBS? A. There has been very impressive research on clown’s mustard (in combination with other herbs). And, it has been used with great success in Germany for many years to treat IBS and other gastrointestinal diseases. In a study of an herbal combination containing clown’s mustard, 20 patients were given the herbal combination for three to 32 days. They all had been diagnosed with chronic functional disorders for at least one to 20 years. The symptoms the patients experienced included pressure and pain in the abdomen, belching, heartburn, vomiting, nausea, fullness, lack of appetite, constipation, and diarrhea. The patients have been treated for their problems with a variety of antacids, anti-spasmodic agents, and motility-inducing substances. For the purposes of the study, the patients stopped taking these medications and received treatment only with the herbal combination. Abdominal pressure and pain in the abdomen was the most common of all the experienced symptoms, with 11 of the patients rating it as severe. After six days of treatment, only sic of the patients continued to rate their abdominal pain and pressure as severe. After two weeks, this symptom had completely resolved for 16 of the patients. Diarrhea had been rated as severe in five of the patients. By day 14, only one patient continued to have moderate diarrhea. Medications prescribed and taken for cardiovascular diseases, arthritis, and autoimmune diseases often cause gastrointestinal problems. Because these conditions are chronic, these medications must be taken for a long time, often for life. With long-term use, these medications can cause erosion of the stomach lining and actual ulcers. Many of these medication-caused symptoms are similar to IBS symptoms: pressure and pain in the upper abdomen, nausea, abdominal fullness, and lack of appetite. Most, if not all, of the individuals who have gastrointestinal problems caused from medications experience two or more of these IBS symptoms. Forty patients who were taking medications for various types of cardiovascular disease and arthritis, and who are experiencing gastrointestinal problems related to their medications, were enrolled in a study. These symptoms included pressure and pain in the upper abdomen, nausea, abdominal fullness, and lack of appetite. Twenty patients received clown’s mustard combined with other herbs that support gastrointestinal motility. Three days after the trial started, a significant improvement of all s symptoms was noted in those taking this combination. By day 14, abdominal pressure and pain, nausea, and heartburn were completely eliminated in the herbal combination group. Several other clinical trials that were conducted in Germany report similar results. Q. How does this herb compare to prescription drugs? A. A study compared clown’s mustard (combined with other herbs) to Reglan (metoclopramide), which is frequently prescribed to reduce the symptoms of IBS. While metoclopramide is a very effective medication, it also has numerous side effects. Metoclopramide can cause fatigue, anxiety, agitation, jitteriness, insomnia, yellowing of the skin or eyes, changes in vision, hallucinations, and seizures. Because of these serious side effects, metoclopramide must not be taken longer than 12 weeks. In comparison study, 77 subjects were randomized to receive treatment of either clown’s mustard in a combination with other herbs, or metoclopramide. All subjects had pain and pressure in the abdomen, cramping, abdominal fullness, nausea, heartburn, and lack of appetite. The subjects took 20 drops of their assigned treatment after meals three times daily. The duration of treatment was one to two weeks. In both groups, a parallel improvement of all symptoms was observed. At no point in the study was a statistically significant difference in symptoms found. Both treatments significantly reduced pain and pressure in the abdomen, cramping, abdominal fullness, nausea, heartburn, and lack of appetite. In short, both metoclopramide and the clown’s mustard herbal combination worked well at reducing the symptoms of IBS.
However, side effects occurred more frequently and severely in the metoclopramide group. Given the lack of differences noted between the products at reducing symptoms of IBS, it would seem sensible to choose the treatment with the fewest reported side effects and no limits on duration of use. A. Peppermint oil has been shown to relax intestinal smooth muscle. In Great Britain, peppermint oil is currently being prescribed for IBS by physicians and it has been used as a digestive aid and to soothe upset stomachs for generations. Peppermint oil has also been studied for use in an important examination of the colon. A colonoscopy is a procedure of viewing the interior lining of the large intestine (colon) using a colonoscope, a slender, flexible, hollow, lighted tube about the thickness of a finger. A study published in the New England Journal of Medicine supports the idea that even people who are not at risk for colon cancer should have this test. The American Cancer Society recommends that men and women at average risk of colon cancer should have a colonoscopy every 10 years, beginning at age 50. During a colonoscopy, individuals are sedated and almost no discomfort is experienced. The insertion of the colonoscope into the rectum and up through the colon causes some spasming. This is a natural and expected event and the physician performing the exam administers medications that effectively reduce the spasms. A recent study compared the use of peppermint oil and commonly used medications to reduce the colonic spasming in colonoscopy. The peppermint oil was introduced directly into the colon. Effective reduction of colon spasming was observed in 88% of the patients. In a critical review and meta-analysis of peppermint oil for irritable bowel syndrome published in The American Journal of Gastroenterology, eight randomized controlled trials were identified. The studies collectively showed peppermint oil is superior to placebo in improvement of the symptoms of IBS. Because of the good results of these trials, the authors of the review urged additional study of peppermint oil in IBS. However, straight peppermint oil is rapidly absorbed into the blood stream from the stomach. In recent studies comparing enteric-coated peppermint oil capsules and non-enteric coated oil, both preparations provided effective symptom relief. However, the studies concluded the enteric-coated capsules delivered the benefit of the peppermint oil directly to the intestines. In the treatment of IBS, enteric-coated supplemental peppermint is most definitely preferred. In fact, an enteric-coated peppermint oil capsule containing rosemary and thyme is extremely effective in the treatment of IBS. All three of these oils are classified as volatile oils, derivatives found in plants that impart taste and aroma. The combination of peppermint, thyme, and rosemary oils in enteric-coated capsules provides significant relief in IBS-related pain. Q. Can clown’s mustard and other herbs be taken with enteric-coated peppermint oil? A. Yes, peppermint oil capsules and clown’s mustard can be used together. However, depending on the symptoms, individuals with IBS may want to start with one supplement and then add the other if needed. Q. How do consumers find these formulas? A. Fortunately, herbal combinations containing clown’s mustard and enteric-coated peppermint oil capsules are both available at health food stores, natural product supermarkets, pharmacies, and from health professionals. Most knowledgeable sales personnel and health professionals can direct consumers to the most effective products. Q. What should customers look for when purchasing peppermint oil? A. As mentioned before, enteric coating of the peppermint oil is extremely important. The coating prevents the oil from being absorbed in the stomach. The enteric coated-capsule moves through the stomach to the small intestine and eventually to the colon, where it is released for maximum benefit. Q. What is the dosage for peppermint oil? A. The German Commission E approved peppermint oil for the treatment of irritable colon. In enteric-coated form, the Commission E recommends 0.6 ml per day. Enteric-coated peppermint capsules are available. Q. Are there side effects or other contraindications? A. Sometimes, the enteric-coated peppermint oil capsules may cause a transient burning sensation in the rectum when moving bowls. Reducing the dose will correct this. Individuals who must refrain from alcohol should not take clown’s mustard in an herbal tincture, which may contain alcohol. Q. What else can IBS patients do to feel better? A. Food allergies or food intolerance may be associated with IBS. Dairy products and certain grains may trigger a painful episode of IBS. Determining those foods that initiate the problems and eliminating them from your diet can be very helpful. Many people report their symptoms occur after a meal. Hyperactivity of the intestine of IBS is the response. Often, the strength of this response after a meal is in direct relation to the number of calories and he amount of fat in the meal. Reducing saturated fat, limiting calories, and increasing fiber intake may be helpful. Stress also stimulates the intestinal hyperactivity. Relaxation training may reduce some IBS symptoms. Listening to therapeutic audiotapes, hypnosis, counseling, and biofeedback all have been shown to improve the healing response in persons with IBS. Conclusion IBS can be painful and frustrating, capable of causing much distress. While currently there is no cure for IBS, the symptoms can be managed. The pain, abdominal discomfort, and bowel problems of IBS all respond well to treatment with the use of key herbs, including clown’s mustard, and enteric-coated peppermint oil. These herbal combinations can be both effective and safe in treating IBS. Clown’s mustard and enteric-coated peppermint oil are both effective front-line natural alternatives for IBS treatment.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1494) The Power Plant of the Amazon
Date:
March 02, 2007 11:34 AM
Enzymatic Therapy Amazon Herbs It may surprise most Americans to know that rainforest plants are the original source for one-fourth of the chemotherapy medications used today. Plants offer a plethora of beneficial compounds, and rainforests contain a superabundance of beneficial plants. In fact, plant medicines are the most widely used medicines of all types in the world. Over eighty-five percent of the world’s population uses plant and herbal medicines as their primary medicines. That’s 5.1 billion (5,100,000,000) people worldwide! While Americans overwhelmingly use synthetically manufactured pharmaceuticals to cure their ills, the vast majority of Earth’s inhabitants use healing plant medicines instead. One of the most powerful healing rainforest plant medicines is cat’s claw, or Uncaria tomentosa. This high climbing woody vine grows at the base of tall trees in the Peruvian rainforest. The plant’s claw-shaped thorns latch onto the trees and spiral further upward, nourished by the lush rainforest environment. For over 2,000 years, the Ashaninka, a tribal people of the Peruvian rainforest, have used the root of U. tomentosa to treat illnesses in the tribe, including asthma, bladder infections, infected wounds, arthritis, bone pain, bowel inflammation, and cancer. Q. I’ve heard about cat’s claw, but what does it do and how do I know which one is right for me? Cat’s claw might be one of the most confusing (and most effective!) nutritional supplements available in health food stores today. One reason that it’s so confusing is there are so many kinds of cat’s claw supplements-there are cat’s claw leaves, cat’s claw bark, and even cat’s claw twigs. While each of these supplements claim to help the immune system, it is the root of Uncaria tomentosa that is proven to impart the true cat’s claw health benefits. Scientists, who have extensively studied every part of the plant, discovered that extracts made from selected cat’s claw roots possess the healing power to treat and prevent diseases like cancer, rheumatoid arthritis, ulcers and degenerative diseases. In addition, it demonstrates anti-inflammatory, anti-viral and anti-microbial benefits. Adding to the confusion is the fact that not all Uncaria tomentosa roots actually contain healing properties. Healers in the Ashaninka tribe attribute the healing properties in cat’s claw to the “good spirits” that live in the plant’s roots. The Ashaninka healers, or sancoshi, are able to actually “see” the good spirits hidden inside the root of the plant before they harvest them. Some cat’s claw plant roots have the good spirits. Some don’t. If the good spirits are mixed with any cat’s claw root without good spirits, the healing power is lost. While there are no apparent differences in the plants or the roots to the untrained eye, only certain cat’s claw roots possess the power to heal. And, for a very long time, only the Ashaninka tribal healer seemed to be able to identify them. They call the good spirit cat’s claw Saventaro, or “powerful plant”. However, scientists who were given cat’s claw roots by the Ashaninka to study in the laboratory discovered that they could “see” the good spirits, too! Using high performance liquid chromatography, or HPLC, a laboratory process that identifies various chemical compounds, the good spirits of cat’s claw roots were revealed to be important medicinal compounds called pentacyclic oxindole alkaloids (POAs). Research has learned that POAs provide powerful benefits for the human immune response. Q. Why are good spirits, or POA’s, good for the immune system? Cat’s claw POAs work to keep us healthy by directly interacting with white blood cells, the backbone of our immune system. Our white blood cells are the disease fighting cells of the human body. These highly specialized cells fight diseases we catch, such as colds and flu, as well as diseases that start within our own cells, such as cancer and autoimmune diseases. There are many kinds of white blood cells; each has a specific job to do in fighting diseases. Certain POAs help white blood cells called macrophages work faster. The macrophages’ job is to engulf and digest foreign material. This means that macrophages can ingest m ore bacteria and disease causing microbes when they are exposed to POAs. The scientists also discovered that POA cat’s claw extract increases the production of a chemical protein called interleukin that is secreted by macrophages. This macrophage-secreted interleukin (IL-1) has important immune enhancing properties. IL-1 alerts resting white blood cells and spurs them into action. It also helps make other biochemicals that are essential to an activated immune system. POAs also help B cells. B cells are white blood cells that make antibodies that kill germs. Each B cell is programmed to make one specific antibody that is effective against one specific germ (such as a bacteria, virus, or fungus). When scientists looked at the number of B cells after they were exposed to POA cat’s claw root extract, they found that the B cells had increased significantly, resulting in an increased supply of antibodies. And perhaps most importantly as they relate to cancer, the POAs in cat’s claw root extract help increase the number of T cells, the true soldiers of the immune system. There are many different kinds of these white blood cells, including Helper T cells, Suppressor T cells, and Killer T cells. Increased Helper, Suppressor, and Killer T-cells can more effectively destroy cancer cells. Increasing the number of circulating T-cells is very important in a disease like AIDS as well. Q. Can cat’s claw and other plants in the rainforest really cure diseases? Isn’t that just folklore? It’s folk use and modern science combined-plants have long been known for their ability to kill cancer cells. In fact, the National Cancer Institute (NCI) has identified over 3000 plant extracts that can kill cancer cells. More than 70 percent of these plants are found only in the rainforest. Q. What is it about the rainforest that gives plants like cat’s claw these cancer killing compounds? Most of the time when we talk about rainforests, we’re talking about the tropical rainforests. While other forests, like the old-growth temperate forests of the Pacific Northwest, also have high rainfalls and tall trees, the tropical rainforests located near the equator are where most plant medicines come from. The Amazon rainforest in South America is the world’s largest, covering an area about two-thirds the size of the continental United States. Depending on the elevation and distance to the equator the Amazon rainforest receives between 160 and 400 inches of rain per year. The rain is spread pretty evenly from January to December-it’s always the rainy season-and the temperatures remain between 75-80 degrees Fahrenheit all year. This fertile environment continually recycles itself. When leaves fall from the trees, flowers wilt, and animals die in the rainforest-all of the nutrients are recycled back into the roots of the trees and plants. Because the rainforest reuses almost everything that falls to the ground, the plant growth is amazingly rich in alkaloids and other medicinal compounds. Researchers think these compounds and alkaloids, like POAs, protect the plants from illness and insect attacks. These are the very same compounds that protect us from disease. Q. When the Ashaninka harvest the cat’s claw roots, does it impact the rest of the plant? No. The Ashaninka work intelligently to keep rainforest cat’s claw plants perpetually healthy. The Ashaninka employ responsible and innovative harvesting techniques to keep the plants alive and tribal members healthy. Individual cat’s claw plants are never completely harvested. Only one third of the lateral roots are collected at any one time to allow re-growth by the remaining root. Once a plant’s lateral roots have been partially harvested, that plant is left to regenerate, and no more root is harvested from it for 10 years. Q. Why are the Ashaninka willing to share their cat’s claw? They are generous people. The Ashaninka see no benefit in hoarding cat’s claw for themselves alone. They also want to make sure that the plant’s healing properties continue on. As their homelands continue to be destroyed by deforestation, rainforest peoples are also disappearing. There were an estimated ten million tribal and indigenous peoples living in the Amazonian Rainforest in 1510. Today there are less than 200,000. Since the 1900’s more than 90 indigenous tribes have died out and disappeared. Each time a rainforest medicine man or woman dies without Passing their arts on to the next generation, the tribe and the world loses thousands of years of irreplaceable knowledge about medicinal plants. With them, centuries of accumulated knowledge of the medicinal value of rainforest species have been lost. A good example of the impact of this loss can be seen in cat’s claw. When European explorers began venturing into the Amazon River basin, t hey were skeptical of the stories the Ashaninka people told them of U. tomentosa’s amazing healing powers. But when the explorers became sick with colds, flu, or other illnesses, they harvested cat’s claw root for themselves and gave the plant a try. Sometimes the explorers got better when they used the cat’s claw root, sometimes they stayed the same. Q. Why didn’t the cat’s claw root help all the explorers? Because some cat’s claw plant roots have good spirits-POAs-and some cat’s claw plant roots have tetracyclic oxindole alkaloids, or TOAs. While the POAs have very powerful effects in the immune system, the TOAs have different effects in the body, none of which help the immune system cells at all. All U. tomentosa plants look virtually identical, so it’s hard to tell if they have the healing POAs or non-helpful TOAs. What makes cat’s claw identification even more challenging is the fact that plants with POAs one year will have TOAs the next. Cat’s claw plants seem to change their alkaloid chemotypes at will, an incredibly powerful accomplishment for a plant to possess. Harvesting of cat’s claw roots that contain POAs is very tricky. Unless the person gathering the root extract is an Ashaninka sancoshi. These medicine men know which cat’s claw to use; they can actually “see” the good spirits hidden inside the root. When scientists studying cat’s claw discovered they could “see” presence of TOAs using HPLC technology, they were able to harvest cat’s claw root extracts with POAs that consistently helps people get and stay healthy. Q. Do some cat’s claw root extract supplements contain TOAs? Yes they do. And buying those products will only benefit the cat’s claw distributor; they won’t help you stay healthy. When cat’s claw root is harvested from the rainforest, responsible supplement maker examine the root with HPLC to make sure that only POA roots are collected. But, this identification of the chemotypes takes significant time and costs money. For these reasons, many cat’s claw distributors don’t include this important process in their harvesting. The POAs and TOAs are simply just mixed together and sold as a cat’s claw product with no mention of any alkaloid content on the label. Q. Why should I avoid TOAs? While the POAs in cat’s claw root extracts have numerous benefits to the immune system, the TOAs have different effects in the body, none helping the immune system cells. Most importantly, however, when POAs and TOAs are mixed together, the TOAs actually work against the POAs. TOAs reduce the capacity of POAs to beneficially modulate the immune system. Q. How can I be sure the cat’s claw I buy is POA cat’s claw? Read the label of the cat’s claw root extract product you are considering buying. If it does not clearly state that it is the high POA cat’s claw, then chances are that it’s not. Q. What do the Ashaninka receive in return for the cat’s claw harvesting? The Ashaninka and reputable distributors of cat’s claw root extract have established a mutual and ethical relationship. Both groups benefit from the sale of the plant material. Maintaining this relationship is important for both the tribe and the distributors. The distributors are paying a fair price for the raw material directly to the tribe. No intermediary is involved. This payment covers the raw material itself, a license-fee for the k knowledge of the plant, and a guarantee (from both sides) of a lasting relationship. Payment is also made for the protection of the rainforest. No deforestation is allowed. The area where the cat’s claw materials are processed is also leased and payment is made for this, as well. This arrangement allows the Ashaninka to make independent decisions in how to spend this income from sale of their cat’s claw plants. They have been able to make improvements in the tribe’s water supply and in their living areas. They are also able to obtain outside medical aid as needed and provide for education of their children. The partnership with cat’s claw distributors has created a sustainable resource for the Ashaninka. The tribe has been able to not only preserve their rainforest, but also compete financially with unsustainable income sources offered by timber and agricultural firms. Q. Why is it important to preserve the rainforest? The most amazing fact about these impressive medicinal plants is the vast number that5 has yet to be discovered. In fact, the rainforest’s abundance is one reason it is home to so many healing plants. Within a four square mile patch of rainforest, you could see 1500 species of flowering plants, 750 species of trees, 125 mammal species, 400 species of birds, 100 reptile species, 60 amphibian species, and 150 different species of butterflies. Unfortunately, not everyone looks to the rainforest for the same reasons. Many consider its real value in board feet and cultivated acreage. The forces pushing industrial development move quickly; experts estimate that we’re losing over 130 plant, animal, and insect species every day/ That amount to almost 50,000 species a year. A combination of logging, petroleum interests, cattle grazing operations, and, of course, our own consumer appetites are putting pressure on rainforest resources. The consequences are sobering:
By leaving the rainforest intact, however, and harvesting its many nuts, fruits, oil-producing, and medicinal plants, the rainforest has more economic value than if it was cut down for timber or to make grazing land for cattle. If managed properly, the rainforest can provide the world’s need for sustainably harvested natural resources on a perpetual basis. That’s what the Ashaninka are doing with their cat’s claw harvesting. Conclusion The discovery of medicinal plants is dependent upon healthy rainforests. When an acre of tropical rainforest is lost due to deforestation, the impact on the number of plant and animal species lost and their possible uses is staggering. We can all help the development of sustainable rainforest industries. By purchasing renewable and sustainable rainforest products, like POA type cat’s claw root extract, we are keeping rainforests alive and well. By benefiting from the innate wisdom of the Ashaninka people we are keeping ourselves just as alive and well. By honoring the science and the sacred of the world’s rainforests, like my friend the oncology nurse, the massive wealth and diversity will be there for generations to come.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1476) New Natural Energy Drink - LifeBlast Extreme Energy Drink
Date:
April 01, 2006 12:20 PM
New Natural Energy Drink For most folks, the world seems to be spinning at a faster pace than ever before. Twelve-hour work days, family responsibilities, social commitments, volunteering, spiritual life—and don’t forget that hour at the gym!—all seem impossibly crammed into an all too short 24 hours forget about downtime. As life becomes more difficult and demanding with every Passing day, many people are looking for products that can help them be more productive and keep up with the pressures of the modern world. A lot of those would-be movers and shakers are turning to energy drinks to give them that extra edge. These drinks make up a phenomenal market that scores huge numbers with patrons the world over. However, the energy drinks sold in convenience stores and supermarkets are anything but healthy. Filled with chemicals sweeteners, synthetic stimulants and artificial colors, mass market energy drinks will only drain consumers of their vigor in the long run. Now, a better alternative, a natural product that provides all the benefits of these quick-jolt energy products with healthier ingredients: Nature’s Plus LifeBlast Extreme Energy. LifeBlast offers inner vitality with a potent profile of the most energizing vitamins and herbs. With each sip of luscious, succulent Berry Blast flavor and invigorating nutrition, this eight once drink takes energy to exhilarating new heights. Each serving delivers 1260mg of the most energizing nutrients energy formula available. The extreme energy blend delivers many essential energy nutrients; each serving provides 120% of the recommended daily amount of Vitamin C, 80% of niacin, 110% of vitamin B-6, 110% of vitamin B-12 and 70% of pantothenic acid. In addition, LifeBlast consists of numerous energizing and rejuvenating vitamins and herbal cofactors that will deliver a burst of energy without the jitters, such as taurine, guarana, inositol, carnitine and ginseng. One of LifeBlast’s greatest features, though, is what it doesn’t have. There are no unnatural ingredients that you may find in other energy drinks. LifeBlast contains no aspartame, acesulfame K, glucuronolacone, synthetic caffeine or artificial flavors and colors. LifeBlast satisfies the demand for a delicious, enlivening and nutritious energy beverage. It also meets the requirements for a quality formulation with a clean nutrient profile. LifeBlast delivers amazing energy to its users and is only available in health food stores. Whether the customer is seeking sharper mental focus, peak performance or enhanced endurance, LifeBlast Extreme Energy delivers the pure, exhilarating energy that will propel customers to success. Its time to blast off with Natures Plus LifeBlast Extreme Energy!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1245) Nutritional Supplements Could Save U.S. $6.5 Billion.
Date:
January 07, 2006 12:26 PM
Health Care Crisis Bankrupting U.S. BudgetNutritional Supplements Could Save U.S. $6.5 Billion. You probably never heard about it on the radio, nor saw its actions reported on CNN. Others can’t guess what its acronym stands for. The United States Government Accountability Office (GAO) is an investigative arm of Congress examining the receipt and payment of public funds. This government office exists for the sole purpose of communicating to Congress those facts and figures which we, as a society, can’t afford to overlook. And they are saying that the healthcare system is going to bankrupt us. The agency recently issued a special report called 21st Century Challenges, which concludes that current U.S. fiscal policies are unsustainable and, unless radical changes are initiated relatively soon, will “result in large, escalating, and persistent deficits. The Money Pit According to the GAO report, the United States spends more than 15% of our gross domestic product on health care, and that figures growing fast. We spend a larger percentage than is spent by any other industrialized country. What’s even more suprising is how little we get for the money. An estimated 45million Americans are uninsured. The United States continues to compare abysmally to the other industrialized nations in critical areas like infant mortality, life expectancy, and premature and preventable deaths. Medicare and Medicaid together devour 20% of the federal budget. With the baby boomers—individuals born between the end of WWII 1960—hitting retirement age this year, those figures will only grow larger with each Passing year. Unless, as the GAO report says, something is done quickly. A report released just weeks ago by the Dietary Supplement Education Alliance (DSEA) demonstrates that the government can save at least 6.5 billion in health care cost reductions if nutritional supplements are integerated into the healthcare system. The Lewin Group, a market research firm, developed a report, entitled: Increasing Quality of Life While Minimizing Costs. It focused in on just two supplements, both of which concern reduction in disease prevention for people over age 65. Omega-3 oil, popular for its reduction in coronary heart disease, is projected to save 3.1 billion dollars. Lutein and Zeaxanthin, which supports healthy vision, will save 2.5 billion dollars if this supplement is added to health care plans, according to the study. Savings would come from reduced hospitalizations and doctor’s fees, as well as reduced nursing home use for those who in good health, could remain independent rather than needing to transfer to live-in care facilities. Critical Mass Early last month, a bipartisan caucus on dietary supplements kicked off. It will be co-chaired by Rep. Chris Cannon (R-Utah), and Rep. Fran Pallone (D-N.J.), and its goal will be to examine the manner in which nutritional supplements may become a component of healthcare reform, such as part of an individual flexible Spending Account or health Saving account. As the GAO report indicates, the government interest is reaching critical mass and nutritional supplements are on the verge of entering a new era. As Congressman Cannon said during a November 2nd press conference, government needs to develop a sound policy supporting nutritional supplements “As more and more Americans start taking responsibility for their own health.” Sources/Links for Further Reading: Visit the website of the United States Government Accountability Office. //www.gao.gov/ House Government Reform Subcommittee on Human Rights Wellness. //reform.house.gov/ For more information about the Lewin Group’s Health Impact Study, please visit: //www.supplementinfo.org/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1172) HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (HPLC)
Date:
December 27, 2005 09:08 AM
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (HPLC)HPLC is used to examine and verify potency claims on finished products and/or raw materials. For example, we use HPLC to measure the amount of active SAMe ion in our SAMe supplements, or the parthenolide content in organic feverfew herb. HPLC allows scientists to target and separate specific active ingredients from a solution by Passing it through a sophisticated separation column combined with a mobile phase. The separated ingredients are then measured using ultraviolet light or other detection methods. Development of HPLC methods is a complex and precise science involving significant cost.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1085) HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (HPLC)
Date:
December 27, 2005 09:08 AM
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (HPLC)HPLC is used to examine and verify potency claims on finished products and/or raw materials. For example, we use HPLC to measure the amount of active SAMe ion in our SAMe supplements, or the parthenolide content in organic feverfew herb. HPLC allows scientists to target and separate specific active ingredients from a solution by Passing it through a sophisticated separation column combined with a mobile phase. The separated ingredients are then measured using ultraviolet light or other detection methods. Development of HPLC methods is a complex and precise science involving significant cost.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1084) GliSODin Anti-Aging and Antioxidant Protection
Date:
December 19, 2005 08:47 AM
GliSODin Anti-Aging and Antioxidant Protection
In the time it takes you to finish reading this article, you, your body and your cells will have aged. Some, more than others. Nevertheless, every second that ticks away should serve as a reminder that our time here is temporary. How much time we actually end up with depends on many things. Diet. Lifestyle. Environment. Superoxide Dismutase? I’ll explain. What some of the healthiest individuals fail to realize is that our bodies age from the inside out. Aging is not the result of Passing time, but rather the result of what we’re exposed to environmentally, physically and chemically. It is the integrity of our cells, not our clocks, that determine how smooth the aging process fares. Each day, we’re subjected to millions of elements that affect us in ways seldom seen, felt or noticed. From the moment we’re born, we rely on our cells to work around the clock - producing energy, fighting infections and sustaining life. These same cells eventually determine the rate at which we show (or hide) our age. Taking into consideration that our planet has no shortage of toxins & germs, the need to safeguard our cells becomes very real. Constant exposure to exhaust, secondhand smoke, heavy metals, lead, fluoride and uncountable other noxious compounds should ideally provide us with nothing more than a routine immune system workout. Unfortunately, over long periods they hinder our “resistance” abilities and become stepping stones to accelerated aging. Antioxidants. We’ve all heard the term before, and may even have a general understanding of their role. But to better grasp just how vital they are, it helps to know what’s happening at the cellular level. Free radicals are unstable molecular thieves that often lack electrons. To compensate, they rob healthy cells - a process better known as oxidation. Antioxidants work with the immune system to prevent oxidation, and clean up the mess it leaves behind. Hence, the name. There are two types. Exogenous antioxidants are derived from our diet and include vitamins A, E, and C along with others such as alpha lipoic acid, selenium, CoQ10, grape seed, pycnogenol and zinc. To date, we’ve been limited to exogenous antioxidants as a way to increase the rate at which our body wards off oxidation. They are not, however, our first line of defense. At birth, each and every one of us is equipped with three primary endogenous enzymatic antioxidants; SOD (Superoxide Dismutase), Glutathione Peroxidase (GPx) and Catalase. While both types of antioxidants are beneficial, we’ve become reliant on those from the diet to compensate for our inability to boost the effectiveness of our 3 primary antioxidants. For years, researchers have been examining ways to enhance the activity of our built-in bodyguards. One in particular, Superoxide Dismutase (SOD) has been of foremost interest. SOD targets what many researchers regard as one of our greatest health threats and aging accelerators - Superoxide radicals. These highly reactive, merciless molecules incite enormous amounts of oxidative stress and are capable of wreaking havoc on healthy cells. When cells are left unprotected by SOD, the results can be disastrous - respiratory problems, premature aging, memory loss, cardiovascular challenges, vision failure and joint structure damage, among others. Until now, we’ve been at the mercy of our natural SOD reserves to fight superoxides. Researchers have been working feverishly to produce an effective oral SOD supplement, but have continually encountered a frustrating hurdle - exposure to gastric acid denatures SOD, rendering it useless. As a result, the only effective way to supplement SOD was through injections. These, however, only yielded short-term spikes. And then something remarkable happened that changed everything. Nutrition scientists in France determined that by combining Cucumus melo (a melon high in SOD) with a wheat gliadin stabilizer, it would be possible to prevent SOD from deteriorating in the digestive tract, while preserving it in the blood for extended periods. Not only is this the answer to a puzzle that has plagued researchers, it’s a breakthrough that will impact the life of anyone seeking longevity and vitality. As the first proven oral SOD supplement ever introduced to the public, GliSODin® has taken antioxidant protection, immune support and antiaging science to an entirely new level. The primary function of GliSODin® is to scour the body for superoxide radicals and reduce them to less reactive ions that can be swept away; a process known as dismutation. In addition, GliSODin® reduces the oxidation vulnerability of healthy cells, protects mitochondrial activity and safeguards DNA structure. What’s most remarkable is that GliSODin® has actually been shown to stimulate the body’s own natural production of all three enzymatic antioxidants, including SOD. For the first time in history, we will have the ability to enhance the effectiveness of our body’s primary defense mechanism. New GliSODin® from NOW® represents the ultimate in antioxidant protection. By increasing one’s level of SOD while stimulating the natural production of Glutathione Peroxidase and Catalase, GliSODin® delivers antioxidant protection unlike any previously released dietary supplement. Remember, the aging process begins at a level that we simply can not see, the cellular level. Shielding your cells from superoxide damage is one of the smartest steps you can take against aging before your due time. GliSODin® has made this a reality.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1037) Coming out of depression.
Date:
October 28, 2005 02:46 PM
If a positive outlook is the sun, then depression is a heavy shade drawn across one’s existence. Clinical depression is not the Passing blue mood or feelings of sadness, grief and sorrow in the face of life’s more somber moments. But when sadness seems never-ending, when you can’t concentrate, sleep or enjoy anything, when you feel hopeless and that life isn’t worth the bother—now that’s depression. If your moods are especially dark, seek professional help. What you may be experiencing, though, is more of a sneeze n’ sniffle melancholy than the heavy chest-cold kind (and the analogy is apt, given how common a disorder depression truly is). If that’s the case, you may find the following supplements helpful: Omega-3 Fatty acids: A healthy brain needs plenty of these healthy fats. Flax seed oil and fish oil are two common sources. SAM-e: This naturally occurring substance helps activate serotonin and dopamine, two brain chemicals vital to healthy mood. St. John’s Wort: One of the best-known natural depression fighters, St. John’s Wort also helps reduce the mild anxiety that often accompanies depression. It usually takes four to six weeks to reach full effectiveness. Tryptophan: An amino acid the body uses to create serotonin. Natural tryptophan is found in milk protein concentrate. Speak with health care practitioner if you are taking prescription medications for depression (or any other condition, for that matter). Do not stop taking synthetic antidepressants without proper guidance.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=903) Research on SAMe....
Date:
October 26, 2005 12:49 PM
Two groups of researchers have conducted analyses of trials that utilized SAM-e for mood enhancement. One meta-analysis was published in 1994. The researchers analyzed the efficacy of SAM-e in oral or injection forms based on published trials dated between 1973 and 1992. The authors concluded that there was a significant improvement of 17 to 38% seen in trials of SAM-e compared to placebo response. They state that the efficacy of SAM-e was superior to placebo and its administration caused few side effects.5 A second review was published in 2002. The authors analyzed studies in which SAM-e doses ranged from 200 to 1600 mg daily. They also found a significant effect of SAM-e in comparison to placebo, with an evident rapid onset of effect at enhancing mood.6 Promotes Joint Comfort and Mobility* As a sulfur donor to connective tissue, SAM-e plays a major role in protecting the integrity of cartilage tissue. An in vitro trial assessed the actions of SAM-e in cultured human articular chondrocytes. At a concentration of 10 micrograms/ml, proteoglycan synthesis and sulfate residue incorporation in chondrocytes was shown to be 60% higher than control levels. Based on these results, it was shown that SAM-e has a positive influence on the growth and health of cartilaginous connective tissue.7 In a double-blind trial with 734 individuals with compromised joint health. SAM-e given orally at a dose of 1200 mg daily for 30 days was shown to significantly promote joint comfort compared to placebo, with a high level of tolerability and low incidence of side effects. The researchers concluded that SAM-e is a highly effective supplement for enhancing joint comfort.8 Another trial evaluated the response of individuals experiencing discomfort in the joints to a regimen of 1200 mg SAM-e for 1 week followed by 800 mg for the second week, and then 400 mg for weeks 3 through 8. This open trial of 20, 641 people showed a strong ability of SAM-e to enhance feelings of comfort within the joints. The treatment was rated as “very good” or “good” in 71% of the participants, with an additional 21% rating the treatment effect as “moderate”.9 In a long-term trial lasting 24 months, SAM-e was given to 108 participants with compromised joint function. Individuals were given 600 mg orally per day for the first two weeks followed by 400 mg daily for the remainder of the trial. Individuals experienced significant enhancements in joint comfort, with dramatic improvements noted after 2-4 weeks of treatment. Improvements continued to 6 months and beyond.10 In addition to the above studies, a review was conducted in 1987 to assess the results of SAM-e supplementation in clinical trials for enhancing joint mobility and function. Over 22,000 individuals had participated in the clinical trials that were the subject of this review. The author concluded from his analysis that SAM-e was shown to be highly efficacious, rivaling or surPassing the effectiveness of other treatments, and also possessing a high level of safety.11 Because of this, SAM-e may be the treatment of choice for enhancing joint function. Supports Liver Health and Detoxification* SAM-e supplementation can have profound benefits on liver function. These benefits center around its function as the major methyl donor in the liver, as well as its lipotropic activity. SAM-e also enhances the production of the antioxidant glutathione. A number of trials have been conducted showing the ability of SAM-e to support liver detoxification functions and enhance liver health in individuals susceptible to toxin-induced liver compromise. SAM-e has the ability to normalize liver function by increasing the activity of enzymes needed to upregulate liver detoxification. These effects are comprehensive and rapid. Dosages used in these studies range from 600 mg to 1600 mg daily for 2 months to two years.12,13,14 In these trials, significant benefits of SAM-e supplementation were seen over placebo. Safety SAM-e has an excellent safety profile and is considered well-suited for long term use based on multiple clinical trials. Individuals diagnosed with manic depression should avoid SAM-e supplementation, as it may aggravate the manic phase *This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Scientific References 1. Agnoli A, Andreoli V, Casacchia M, Cerbo R. Effect of s-adenosyl-l-methionine (SAMe) upon depressive symptoms. J Psychiatr Res. 1976;13(1):43-54. 2. De Leo D. S-adenosylmethionine as an antidepressant. Curr Ther Research. 1987;41(6):865-70. 3. Kagan BL, Sultzer DL, Rosenlicht N,Gerner RH. Oral S-adenosylmethionine in depression: a randomized, double-blind, placebo-controlled trial. Am J Psychiatry. 1990 May;147(5):591-5. 4.Salmaggi P,Bressa GM,Nicchia G,Coniglio M,La Greca P,Le Grazie C.Doubleblind, placebo-controlled study of S-adenosyl-L-methionine in depressed postmenopausal women. Psychother Psychosom. 1993;59(1):34-40. 5. Bressa GM. S-adenosyl-l-methionine (SAMe) as antidepressant: metaanalysis of clinical studies. Acta Neurol Scand Suppl. 1994;154:7-14. 6.Mischoulon D, Fava M. Role of S-adenosyl-L-methionine in the treatment of depression: a review of the evidence. Am J Clin Nutr. 2002 Nov;76(5):1158S-61S. 7. Harmand MF, Vilamitjana J,Maloche E, Duphil R, Ducassou D. Effects of Sadenosylmethionine on human articular chondrocyte differentiation. An in vitro study. Am J Med. 1987 Nov 20;83(5A):48-54. 8. Caruso I, . Italian double-blind multicenter study comparing S-adenosylmethionine, naproxen, and placebo in the treatment of degenerative joint disease. Am J Med. 1987 Nov 20;83(5A):66-71. 9. Berger R, Nowak H. A new medical approach to the treatment of osteoarthritis. Report of an open phase IV study with ademetionine (Gumbaral). Am J Med. 1987 Nov 20;83(5A):84-8. 10. Konig B. A long-term (two years) clinical trial with S-adenosylmethionine for the treatment of osteoarthritis. Am J Med. 1987 Nov 20;83(5A):89-94. 11. di Padova C. S-adenosylmethionine in the treatment of osteoarthritis. Review of the clinical studies. Am J Med. 1987 Nov 20;83(5A):60-5. 12. Frezza M, et al. S-adenosylmethionine counteracts oral contraceptive hepatotoxicity in women. Am J Med Sci. 1987; 293(4):234-238. 13. Frezza M, Surrenti C, Manzillo G, Fiaccadori F, Bortolini M, Di Padova C. Oral S-adenosylmethionine in the symptomatic treatment of intrahepatic cholestasis. A double-blind, placebo-controlled study. Gastroenterology. 1990 Jul;99(1):211-5. 14. Mato JM, et al. S-adenosylmethionine in alcoholic liver cirrhosis: a randomized, placebo-controlled, double-blind, multicenter clinical trial. J Hepatol. 1999 Jun;30(6):1081-9.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=900) Cuddlin’ in the Kitchen
Date:
July 27, 2005 03:44 PM
Cuddlin’ in the Kitchen You and your sweetie can turn up the heat by cooking together. Since the beginning of time, the pleasures of the table have been intertwined with those of the boudoir. (Remember the scene in the film Tom Jomes in which Tom and his amorata-of-the-moment wolf down a meal while staring lustily into each other’s eyes?) But when most of your kitchen time is spent trying to get everyone fed and out of the house in time for the night’s soccer game/ PTA meeting/ballet lesson, it can be tough keeping the pilot light lit on your love. That’s why one of the best ways to spice up your sex life is to prepare a sensuous meal together sans offspring (thank heavens for doting grandparents with spare rooms!). A little fourhanded cooking- preferably while sharing some suggestive banter- can create chemistry that allows your playful, non-parenting side s to emerge, enhancing intimacy and setting the stage for the seductive feast to follow. Just as the frenzied pace of modern living can often foster a sense of separation, cooking together as a couple can promote a sense of union. “Eventually you get a feel for your partner’s rhythms and adjust yours accordingly,” says food TV personality Jacqui Malouf, author of Booty Food (Bloomsbury). “Before you know it you’re Passing the coriander, peeling the potatoes and stirring the risotto at precisely the right moments.” With time, you can learn what each of you does best: Who has a flair for combining spices in just the right proportions? Who can chop carrots into perfect little matchsticks without taking all night? Since nothing kills the mood more than arguing over who misplaced the baker’s chocolate or the pasta platter, buy your ingredients earlier in the day and have all the necessary utensils out and at the ready. (Safety note: while two in a tiny kitchen can be steamily cozy, do be careful with hot pots and sharp knives.) Four hands can also be better than two, so why not make the most of it? Malouf suggests approaching your combined efforts with a sense of adventure: “Use more than three ingredients in a salad dressing! Be daring with your desserts! Try concocting something with squab or squid or quince or quail- the sky’s the limit.” Intriguing Ingredients One advantage of using exotic ingredients (or at least foods not normally found on your weekly shopping list) is that they can help you and your partner break through the limits of everyday experience by reawakening long-dormant senses. Go ahead- run your fingertips over the rough rind of a pomegranate before feeling the smooth, full seeds within. Inhale the sweet, perfumed scent of a dead-ripe apricot, and appreciate its downy skin. Admire the cool green beauty of a cut avocado, and share a spoonful with your sweetie. Avocado, in fact, is one of the foods known for inflaming passion based on its suggestive shape, along with artichoke and asparagus- and that’s just the AS! (Chocoholics rejoice: Chocolate, full of the same feel-good chemical released by the brain when one falls in love, also makes the ecstasy encouraging grade, even when obtained in standard shapes.) “coincidentally, many foods long considered aphrodisiacs are low in fat (avocado and chocolate are delectably healthy exceptions) and are high in vitamins and minerals,” write Martha Hopkins and Randall Lockridge in Intercourses: An Aphrodisiac Cookbook (Terrace Publishing). “A diet heavy in these foods, then, yields a healthy blood healthy body with the energy, blood flow and nutrients needed for a peak sexual experience.” (The way these foods feed the imagination- the ultimate smorgasbord of pleasure- is a bountiful bonus.) Other foods, such as honey, have been treasured for supplying the energy needed to fan love’s flames far into the night; no wonder the sweet, sticky stuff shows up in a number of naughty-night concoctions. Just as Venus, the Roman goddess of love, emerged fully formed from the sea, so do the foods that best encourage those under her spell. In addition to being chockfull of healthy protein, “seafood is elegant, clean and light enough to keep your sleek loving machine fully fueled but never weighed down,” says Jacqui Malouf. Oysters are famous- or infamous- for their amorous effects (Cassanova was fond of them) but aren’t for everyone; other romantic dining favorites include shrimp or scallops. Time to Eat Once you’ve worked your kitchen magic together, it’s time to move the action into the dining room. Again, a little preparation can keep the evening at a slow, sensuous boil. Use the best china you have, along with matching silverware, cloth napkins and nice glasses (sippy cups don’t count). The warm glow of candlelight can both set off your tantalizing table and set your hearts aflame, along with a rose or two in the most decorative vase you own. Music (from Mozart to Motown, depending on your taste) is another surefire mojo mover. But please guys- catch up with CNN or ESPN some other time. When you do finally sit down to dinner don’t rush, even (especially) if fast-forward eating is the norm in your house. “Treat the food as if you are making love for the first time,” advises Kerry McCloskey in The Ultimate Sex Diet (True Courage Press). “Before putting any in your mouth, inhale its aroma to get your digestive juices flowing…Cut your food into small, bite-sized pieces, (which) will ensure that you enjoy each bite.” The idea is to enhance all of your senses, which will come in handy later on in the evening. You can make your couple dining experience even more intimate by feeding each other; some foods. Like asparagus spears and shrimp, beg for finger-feeding. McCloskey recommends also trying chopsticks: “Because it will take longer to maneuver your food when using them, you will feel full sooner with less food.” That’s important since you don’t want to overeat- Passing out right after dessert is not the way to impress your partner (they’ve seen you snoring away on the couch a hundred times before).
In the wee hours, happily exhausted, you can ponder this: No matter how hectic your lives get, you should always make time for each other. You already share a mortgage and kids. Cooking together is a great way to share sensuality, too.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=710) Strengthens and Protects the Heart
Date:
July 26, 2005 03:11 PM
Strengthens and Protects the Heart The highest concentration of CoQ10 in the human body occurs in heart muscle tissue, the hardest working muscle in the body. Studies are increasingly showing an ability of CoQ10 to improve energy production in heart cell mitochondria by byPassing defective components in the respiratory chain, as well as to protect heart tissue from the effects of chronic oxidative stress.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=684) MILK THISTLE (Silybum marianum)
Date:
July 12, 2005 09:45 AM
MILK THISTLE (Silybum marianum)COMMON NAMES: Christ’s Crown, Holy Thistle, Venus Thistle, Heal Thistle, Wand of God’s Grace PLANT PARTS: ripe seeds, or extract from the shell ACTIVE COMPOUNDS: Seed extract contains a complex of three flavanolignans which are collectively referred to as silymarin. These flavonoid-like compounds are silibin, silychristin and silydianin. PHARMACOLOGY: The flavonoids contained in Milk Thistle have a strong liver protective action and have been extensively used in Europe as pharmaceutical p reparations for liver disorders. These include: silibin, silydianin and silychristin, which all combine to create silymarin. Clinical trials have shown that silymarin can protect the liver by counteracting a number of toxic substances including alcohol, acetaminophen, carbon tetrachloride and the Amanita mushroom poison. Apparently, silymarin actually alters liver cell membranes which prevent toxins from Passing through the cell. It inhibits the release or the synthesis of certain enzymes which are toxic to liver tissue. In addition, these compounds stimulate cellular growth and reproduction by boosting protein synthesis. Milk Thistle seeds are also high in betaine hydrochloride, which may contribute to the hepato-protective properties of the plant. Silymarin has also exhibited significant antioxidant capabilities and can help reduce inflammation by inhibiting certain enzymes. The seeds of the plants appear to have the highest concentration of silymarin. VITAMIN AND MINERAL CONTENT: rich in bioflavonoids CHARACTER: hepato-tonic, alterative, demulcent and protective BODY SYSTEMS TARGETED: liver, gallbladder, pancreas and stomach.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=577) Nature's Cancer fighters ...
Date:
July 07, 2005 12:36 PM
Cancer has always been a word no one wants to hear from a doctor's lips. But as a fatal disease, cancer has gone from dread to worse, Passing heart disease as the number-one killer of Americans under the age of 85 (a category that includes the overwhelming majority of us). While death rates for both illnesses has dropped over the past few years, the improvement has been much more pronounced for cardiovascular disorders. According to the American Cancer Society, 476,009 people died of cancer in 2002 (the last year for which statistics are available). Behind every one of those numbers is a web of lives tangled by cancer's relentless onslaught: A child who misses a mother's comforting arms, a bride without a father to walk her down the aisle, a spouse coming home to a dark, cold house every night. And for those fortunate enough to survive a cancer encounter, there's always the dark worry of recurrence that surfaces with every ache or twinge. Many people think of cancer as either a random calamity of a genetically driven inevitability, but it ain't necessarily so. Diet is coming up big as a major cancer-risk player: For example, eating a lot of red meat, especially highly processed meats such as bacon, has been linked to high colorectal cancer risk in an investigation published by the Journal of the American Medical Association. On the positive side, a number of nutrients have shown cancer-fighting power, such as the recently discovered link between the B vitamin folate and reduced risk of colon and other cancers (see page 57). Other useful nutrients appear on the chart that follows. Of course, risk always varies from person to person, and there are some lifestyle issues, like not smoking, that are no-brainers when it comes to cancer deterrence. But isn't it nice to know that protection from such a terrible disease might be as close as the end of your fork?
Nature's Cancer fightersBerries
Citrus Bioflavonoids
Curcumin
EPA
Green Tea
Lycopene
Mushroom Polysaccarides
Selenium
Soy
Vitamin C
Vitamin D
Vitamin E, Natural
Glossary
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=558) Timed-Release St. John’s Wort Once Daily The Next Generation in Mood Support.
Date:
June 29, 2005 09:37 AM
Timed-Release St. John’s Wort Once Daily The Next Generation in Mood Support. In our high-powered world, countless Americans are searching for a wholesome, natural product to help them maintain a positive outlook and sense of well-being. The remarkable botanical, St. John’s wort, is well-known for its established history of safe use. Now Source Naturals offers you the first and only once-daily, TIMED-RELEASE ST. JOHN’S WORT. This premium botanical is manufactured in a special cellulose base, which is tested to release St. John’s wort over a 12-hour period. Source Naturals tests each production lot of TIMED-RELEASE ST. JOHN’SWORT. This exclusive supplement is standardized to 0.3% hypericin, yielding 2.7 mg in every convenient daily dose— the amount shown in research to support mild to moderate maintenance of a positive mood. At a time when our emotional well-being is challenged by unprecedented stress levels, research into the most convenient and effective natural remedies is critical. Source Naturals is your connection to this research, dedicated to quickly bringing you the benefts of the latest emerging wellness strategies. Popular Choice For a Positive Mood—Now Even Better! St. John’s wort, or Hypericum perforatum, has been valued by diverse cultures as far back as the Middle Ages for its ability to support a positive outlook and sense of well-being. Today modern consumers are experiencing the benefits of this renowned herb, which include mood-brightening, relaxation, alertness, and a sense of overall well-being. Unlike other supplements on the market, Source Naturals TIMED-RELEASE ST. JOHN’SWORT is produced using the most advanced scientific methods. The result is a supplement that offers the once-daily convenience today’s consumers have come to expect. Clinical Trials A review of 23 randomized clinical trials encomPassing 1757 subjects was reported in the British Medical Journal. It showed that St. John’s wort was more effective than placebo for mild to moderate maintenance of a positive mental outlook. The Beneficial Constituents The beneficial constituents of the St. John’s Wort plant are believed to be the naphthodianthrones, especially hypericin and pseudohypericin, and a wide variety of flavonoids. Source Naturals TIMED-RELEASE ST. JOHN’S WORT is standardized to consistently yield 0.3% hypericin. Each convenient once-daily dose contains 900 mg of St. John’s Wort extract, yielding 2.7 mg hypericin. This is the optimal amount found in most studies to support a positive outlook and sense of wellbeing. Benefits may be experienced within 4 to 6 weeks of initial use. Emotional Well-Being: Important Component of the Wellness Revolution Source Naturals is pleased to join with your local health food store in offering you the next generation in St. John’s wort supplementation. TIMED RELEASE ST. JOHN’SWORT can help you support a positive mood with the remarkable properties of the plant world, exclusively formulated for once-daily convenience. This advanced product reflects today’s revolution in natural health care, offering you the benefits of natural, cuttingedge supplementation.
References
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=515) VANADIUM W/CHROMIUM - Supports Healthy Blood Sugar Levels
Date:
June 24, 2005 05:15 PM
Today’s sedentary lifestyles and sugar-rich, nutrient-poor foods are contributing to the rise of obesity in our society. The result: challenges to your body’s system of balancing blood sugar levels and insulin activity. Maintaining a healthy diet and lifestyle helps keep blood sugar levels in the normal range, but sometimes you need nutritional support when you don’t have time to make those healthy food choices. Source Naturals, the science company, introduces VANADIUMW/CHROMIUM for blood sugar support. Research shows that these two important minerals help maintain normal blood sugar levels when used as part of your diet. Vanadium works together with chromium to support healthy blood sugar levels. Research has shown that both of these important minerals play a key role in normal insulin function. Vanadium: Balances Insulin Activity Vanadium, named after Vanadis the Norse goddess of beauty, belongs to a group of biologically important metals known as transition elements. These metals have a natural tendency to form complexes with organic compounds called coordination compounds that serve important biological functions. Insulin is secreted by the pancreas in response to high blood glucose levels after meals. Without insulin, glucose cannot enter cells to provide fuel for cellular energy. The sugar that remains in the blood can create problems by binding with protein molecules, resulting in damaged, non-functioning structures, in a process called glycation. Some evidence suggests that vanadium supports these vital metabolic processes because of its ability to mimic the actions of insulin. More Absorbable Form of Vanadium Absorption of dietary vanadium and supplemental vanadium is poor. It is estimated that less than 5% of dietary vanadium is absorbed. Organic forms of vanadium, such as bis-glycinato oxovanadium or BGOV, are recognized as being more absorbable. BGOV is an organically bound, bioavailable form of vanadium complexed with the amino acid glycine. Glycine, an amino acid found in the protein of all life forms, generates superior vanadium absorption. Chromium: Supports Glucose Metabolism Chromium is a trace element the body needs in very small amounts, but it plays a significant role in human nutrition. Its most important function is to help regulate the amount of glucose in the blood. Insulin plays a role in this process, by regulating the movement of glucose out of the blood and into the cells. Chromium is a key constituent of the compound known as glucose tolerance factor (GTF). This mineral enhances the effectiveness of insulin, encouraging glucose to enter cells, where it can be burned for fuel. Chromium participates in glucose metabolism by enhancing the effects of insulin. Insulin binds to insulin receptors on the surface of cells, activating those receptors and stimulating glucose uptake by cells. Through its interaction with insulin receptors, insulin provides cells with glucose for energy and prevents blood glucose levels from becoming elevated. Glucose buildup in the bloodstream is associated with adverse changes in lipid profiles and increased challenges for cardiovascular health. Some studies examining the effects of chromium supplementation on lipid profiles have observed reduction in serum total cholesterol, LDL cholesterol, and triglyceride levels. Source Naturals VANADIUM W/CHROMIUM includes ChromeMate®, a patented compound of chromium and niacin with proven GTF activity. Wellness Nutrition Taking responsibility for your health is at the heart of the wellness revolution. Sometimes life may seem like it’s Passing you by and you may not have time to focus on staying healthy. Your local health food outlet is a great resource for nutritional education and effective, advanced natural products. Source Naturals is pleased to partner with these outlets to bring you products like VANADIUM W/CHROMIUM to help you maintain a healthy balance. References: Anderson, R.1998. Chromium, glucose intolerance and diabetes. Journal of the American College of Nutrition 17(6):548-555. Jellin, J., et al. 2004. Vanadium Monograph. Pharmacists Letter/Prescribers Letter Natural Medicines Comprehensive Database. Therapeutic Research Facility. Nandhini, S., et al. 1993. Insulin-like effects of bis-glycinato oxovanadium complex on experimental diabetic rats. Indian Journal of Biochemistry and Biophysics 30:73-76.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=420) Garlic for the Ages - eat garlic because it's good for your heart...
Date:
June 13, 2005 09:58 AM
Garlic for the Ages by Phyllis D. Light, RH Energy Times, January 1 , 2004 If you eat garlic because it's good for your heart, you swallow a plant renowned through human history: Garlic was eaten by Roman soldiers for courage; Egyptian slaves ate it to build strength; Christians, Moslems and Hindus include it in their sacred books. Others have used it as an aphrodisiac, a vampire deterrent and a magical charm. Garlic has a long history as a culinary and medicinal herb that people either love or hate. Its pungent aroma and warming flavor captivates or repels, but its wealth of natural chemicals does great things for your heart. Garlic (Allium sativum), a member of the onion family, is native to Siberia but, in modern times, has become a treasured naturalized citizen grown all over the world. Garlic's use in folk medicine dates back about 7,000 years, making it one of the oldest known medicinal foods or herbs. In modern times, garlic is generally used as a condiment lending a unique, pungent flavor to dishes, but in medieval times, garlic was cooked and eaten as a vegetable in its own right. Today you can revel in a wealth of garlic choices, consuming garlic raw, cooked in various recipes, as a dried concentrated powder, as a fresh liquid extract or as aged garlic powder. Powerhouse Herb Each little clove of garlic is a powerhouse of good-for-you natural compounds, vitamins and minerals. The biologically active constituents of garlic include allyl sulfur compounds as well as the minerals germanium and selenium. When you chop up raw garlic and allowed it to stand for about 10 minutes or more, the herb's fragments release an enzyme that converts its compounds from allyl sulfur to another natural chemical called allicin. Although some allicin is found in garlic before it is cut apart, the yield multiplies considerably when the garlic clove is chopped or pressed and exposed to water (Garlic Conference, Newport Beach, 11/15/98; Penn State). Many researchers believe that the more allicin produced, the better the health benefits. (Although this is still being debated among the garlic cognoscenti.) But garlic's benefits don't end meekly on the kitchen counter with its allicin content rising. Cooked garlic and aged garlic contain other helpful chemicals called diallyl sulphides. Consequently, in any form, garlic produces beneficial health effects. Fortunately, since raw garlic juice or oil can often irritate the stomach lining, especially in people with sensitive stomachs and delicate digestive systems, garlic supplements and cooked garlic are both helpful for heart health. Aged Garlic Extract Aging garlic significantly reduces its irritating compounds and makes it easier on the stomach. In the aged form, all of garlic's healthy sulfur-containing compounds are converted to water- soluble compounds that retain garlic's natural health benefits. In addition, the pungent odor of the garlic is greatly reduced, an outcome many people desire. When a group of researchers at Brown University studied the effects of aged garlic extract on people's cholesterol levels, they found that after six months, cholesterol dropped about 6% (Am J Clin Nutr 1996; 64:866-70). In another study from Brown, researchers found that aged garlic extract reduced platelet adhesion, a sticky blood problem that can cause vessel blockages (New Drug Clin 45(3):456-66). When platelets are less sticky, they are less likely to form blood clots that can cause heart attacks. Garlic and Heart Disease A growing body of research shows that a clove of garlic a day can significantly reduce your risk of heart disease. A four-year study of 280 people who took dried garlic powder three times a day found a striking reduction in the types of arterial plaque blockages that threaten the blood supply to your heart. Interestingly, in this particular study, women displayed a greater reduction in plaque than men (Atherosclerosis 2000; 150:437-8). Another study found that garlic may also keep important blood vessels more supple and less likely to spasm. Arterial spasms have been linked to heart attacks and other cardiovascular problems in women. Aortic Complications As you age, the aorta, one of the main arteries that carries blood, may harden, reducing blood flow from the heart and placing damaging stress on a number of other bodily organs. In research at Ohio State University, people who took garlic supplements had 15% less aortic stiffness than people who avoided garlic (Circulation). In this study, scientists found that the older people enjoyed the greatest cardiovascular benefits from daily garlic use. Researchers believe this extra benefit is linked to the fact that as you age, the endothelial tissue in the linings of the aorta and other blood vessels become less responsive to the need to dilate (expand). As a result, when more blood flow is required, and the heart pumps faster, these vessels take more of a beating from the friction of blood Passing through them. That restriction in dilation has two damaging consequences: In one instance, vessel walls can be injured. In response to these injuries, cholesterol collects on artery walls, plaque forms and the blood supply to the heart muscle can be restricted, leading to a heart attack. In other cases, arteries can restrict blood flow to the heart simply because of the inability to expand sufficiently. The Ohio State researchers found that arteries in folks aged 70 to 80 benefited the most from taking garlic. But those in their 60s also benefited significantly. Garlic's natural antioxidant properties can also help protect the heart from damage after surgery (BMC Pharmacology 9/02). In a study performed on lab animals, researchers found that oxidative stress, a source of cell damage that takes place after surgery, dropped when the animals ate a diet that included garlic. Oxidative stress can seriously reduce cardiac function, limit the amount of blood the heart can pump and cause permanent damage to the heart muscle. Garlic Against Blood Clots Under normal circumstances, blood clots serve a useful purpose: Cut yourself and a blood clot stops the bleeding. Without this clotting ability, you might bleed to death. But if your blood is too prone to clotting, these clumps can cut off blood supply to your heart and other organs, endangering your life. In a study of apparently healthy individuals whose relatives had already suffered from heart disease, researchers found that their blood formed thick, tangled blood clots, increasing their risk of heart problems (Circulation rapid access 9/23/02). These blood clots are made of a substance called fibrin, a protein in the plasma that can form elastic threads that cut off blood flow. While these researchers recommended aspirin as an anti-clotting measure for people at risk of heart disease, garlic can also help break up fibrin and possibly lower your chance of heart problems (Pharmatherapy 5(2): 83). The fibrin that forms clots is produced by blood cells called platelets. Other scientists who have looked into garlic's benefits believe that one of its natural chemicals called ajoene may keep platelets from producing excessive fibrin and gumming up the flow of blood through arteries. If you've rarely indulged in garlic, you may need a period of adjustment in growing accustomed to its unique taste and aroma. But its heart benefits confirm the long-ago observation by Pliny, an ancient Roman naturalist, that "garlic has powerful properties."
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=320) Maximum Absorption
Date:
June 10, 2005 03:24 PM
Maximum Absorption by Henry Wolfe Energy Times, July 11, 2003 Nutrients do you no good if you don't absorb them. Eating the right stuff and taking the right nutrients can still be wrong if they never make it out of your digestive tract and into your bloodstream. For instance, dietary supplements usually should be taken along with food. The presence of food in the digestive tract aids the absorption of nutrients. As a general rule, if you take dietary supplements on an empty stomach, most of their contents will probably pass through you and never escape your intestinal tract before they are eventually eliminated. This is particularly true for the fat-soluble nutrients such as vitamins A, D and E. By consuming fatty foods when you take these supplements, you enable your body to absorb a large amount of these valuable substances. But there is at least one exception to this rule: Amino acid supplements (protein building blocks) should usually be taken on an empty stomach. Otherwise the other amino acids present in your meal may interfere with your use of these nutrients and counteract the benefits of the supplements. The Standardization of Herbs Taking herbs presents different challenges than consuming dietary supplements. While the chemical structures of nutrients in supplements are usually precisely identified, the active ingredients in herbs is usually a mixture of chemicals. Often, too, researchers disagree on exactly which active ingredients in herbs produce the health benefits linked to these botanicals. But in an effort to derive the most from these substances, many experts recommend what are called standardized forms. Standardized herbal supplements are formulas that have been created to insure they contain consistent and reliable amounts of certain beneficial chemicals that scientists have identified in these plants. In the creation of these supplements, experts determine the standardized chemicals that are most likely the basis of the herbs' effectiveness. By standardizing certain of the supplements' ingredients, therefore, standardized herbs limit the variation among batches of the product. You can rely on the fact that every purchase will contain the same amount of ingredients taken from the original plant. According to Michael Janson, MD, author of Dr. Janson's New Vitamin Revolution (Penguin/Avery), "Although herbs have a long history of use for medicinal purposes, it is only recently that they have been analyzed to reveal their most active components. These active chemicals are commonly present in very variable amounts in herbs, depending on where and how they are grown, soil quality, when they are harvested, the amount of rain and sun, and other factors. "Standardized herbs have guaranteed specific amounts of the known, active herbal components, as well as the other factors that might be of help but are not as well studied" (www.drjanson.com). Herbalists who specialize in using entire plants in their practices can recommend non-standardized preparations that you can often use. In general, that kind of herbal use is more effective when you secure expert advice. If you lack access to an experienced herbalist and you're choosing botanicals on your own, standardized preparations are easier to take. Absorption From the Gut Most of the nutrients you take in are absorbed through the walls of your digestive tract. This most often takes place in the small intestine. What to watch out for: Fast food, fast living and long work hours afflicts our digestion and can disrupt proper absorption. You have to be relaxed to properly absorb the nutrients in your food and supplements. Consequently, the occasions for meals should be relaxed and enjoyable moments. Set aside enough time to appreciate, taste and thoroughly chew your food. Adequate digestion and absorption begin in your mouth. Another way to increase nutrient absorption is with the use of digestive enzymes. Since the digestive tract depends on the enzymatic breakdown of food that reduces nutrients to absorbable form, taking enzymes can help your intestines make better use of nutrients as they pass through the digestive tract. Normally, enzymes are present in raw food, like uncooked fruits and vegetables. Since most of our food is eaten after it is heated, a process that breaks down enzymes, not many enzymes are present in today's diet. Therefore, taking supplemental enzymes may increase absorption. Beyond Stress Beyond everyday stress, a variety of problems can make absorption go astray, allowing important nutrients to escape and permitting unwanted substances to enter the body. For instance, a significant digestive malfunction that many experts have focused on in recent years is a condition that has come to be called "leaky gut." As Anil Minocha, MD, director of digestive diseases at the Mississippi Medical Center and author of Natural Stomach Care (Avery), points out, "In a healthy individual, the wall of the intestinal tract is designed to absorb food molecules and prevent harmful microorganisms and toxic materials from Passing out through the bowel wall and into the bloodstream. "In today's heavily polluted environment, the gastrointestinal tract of even the healthiest individual is called on to process an overwhelmingly large flow of septic and infectious materials." Because of these digestion destroyers, as we take in a startlingly large amount of viruses, bacteria, toxic chemicals, fungi and processed foods, our digestive systems are often overwhelmed and are rendered unable to perform their tasks correctly. This constant assault on the stomach and intestines takes a serious toll. A frequent product of this process is the digestive walls' loss of their crucial ability to keep out unwanted toxins and organisms as they become, in Dr. Minocha's words, "loosened and inflamed." As a result, instead of keeping out harmful substances and absorbing helpful nutrients, spaces open up that begin to allow in "bulky, partially digested food particles, toxic substances and infectious microbes." According to Dr. Minocha, the first signs of this absorption problem can include complaints such as allergic reactions, skin problems, joint pain, digestive difficulties, nausea, fatigue and lack of energy. To improve your digestive absorption, Dr. Minocha recommends a six-part program that includes these steps: * Detoxification by means of fasting and avoiding harmful items like sugar, over-processed foods, coffee and alcohol * Taking herbs that can help the digestive tract heal, recover and repair itself; these include garlic, ginger and milk thistle * Replenishing the beneficial bacteria of the digestive tract by eating yogurt * Keeping track of your daily diet and eliminating foods that cause allergies and other reactions * Consuming more fruits and vegetables while eating a high-fiber, mostly vegetarian diet * Developing consistent, healthy lifestyle habits; these include not smoking, cutting the size of your meals and eating in moderation, exercising several times a week and controlling stress Young and Old Digestion The nutrients in your diet can also beneficially influence the state of your digestive system and its ability to distinguish among substances that are supposed to gain entrance to your body and those that should be kept out. Since aging can further compromise the discriminatory ability of your gut, Dr. Minocha also recommends a steady diet of antioxidant-rich fruits and vegetables plus supplements to keep your digestive tract functioning at full capacity as you grow older. Among the nutrients he recommends: * Coenzyme Q10: By middle age, your body makes less of this powerful antioxidant that helps cells generate energy in the mitochondria (structures within cells that may decrease with age). Dr. Minocha notes that research demonstrates CoQ10 may be able to help people with diabetes control harmful metabolic byproducts that appear in their bloodstreams. * Natural Lycopene: This antioxidant, responsible for the red of both tomatoes and watermelon, has been shown to lower the risk of both heart disease and prostate cancer. As an antioxidant, natural lycopene also helps protect the digestive tract. Absorption of the proper nutrients may be the key to health for many people. By paying closer attention to the well-being of your digestive tract and practicing lifestyle habits that promote maximum absorption, you may be able to substantially improve your nutrition and your health.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=269) Federal Court Overturns FDA Ban on Ephedra at Low Doses
Date:
June 09, 2005 08:41 AM
Federal Court Overturns FDA Ban on Ephedra at Low Doses by Rakesh M. Amin and Mark Blumenthal A Utah Federal District Court recently limited the scope of a year old Food and Drug Administration’s (FDA) Final Rule1 banning the sale of all ephedrine-alkaloid dietary supplements.2 The Court’s ruling has a limited affect on the ability of companies to sell ephedrine nationally, but is important regarding FDA procedure for creating rules and enforcement powers. Ephedrine alkaloids are found primarily in the controversial herb ephedra (Ephedra sincica Stapf., Ephedraceae). The District Court determined that the FDA’s use of a risk-benefit analysis was against the intent of Congress in Passing the Food, Drug and Cosmetic Act,3 which presumes all foods are safe and requires the FDA to prove the existence of a significant or unreasonable risk. The court held that to require food producers to establish a benefit before selling their product places an improper burden on them and was inconsistent with Congress’s intent when it passed the Dietary Supplement Health and Education Act of 1994 (DSHEA) to clearly place the burden of proof of safety of a dietary ingredient on the FDA.4 Secondly, the court determined the FDA had to show by a preponderance of the evidence “a significant or unreasonable risk of illness or injury.”5 Therefore, in order to ban all sales of a given product, the FDA must first prove that the dosage amount in the product presents an unreasonable risk.6 Prior to this ruling, the FDA was not required to consider dosage size before banning a substance. This ruling has limited effects at the moment since the FDA may appeal this decision. Additionally, the ruling has no effect on the laws of several states (including California, Illinois and New York) which have banned all sales of ephedrine alkaloids in dietary supplements. The ruling also only applies to products containing 10 mg or less of ephedrine alkaloids per daily dosage. Any product exceeding that amount is still banned and will continue to be enforced under the FDA rule.7 The court, in its ruling, specifically precluded the FDA from taking any enforcement action against Nutraceutical Corporation, the company that filed the lawsuit, for its sale of products containing 10mg or less of ephedra and for the FDA to consider further rulemaking “consistent with this Order”.8 However, the court did not specifically instruct the FDA to refrain from taking enforcement action against other brands containing less than 10mg of ephedrine.9 As such, companies considering launching new products containing ephedrine alkaloids are advised to do so carefully. Nutraceutical Corporation president Bruce Hough was cited in The New York Times as saying that the company’s reason for filing the suit was not based on ephedra and that his company had no plans to begin marketing ephedra supplements in the near future.10 Hough was quoted as saying, “We filed it [the lawsuit] because the FDA established rules that could cause problems to the rest of our business.” Hough was referring to the legal basis upon which the FDA banned the sale ephedra. He told the American Botanical Council that the FDA was applying a drug standard of risk vs. benefit to herbs and dietary supplements – technically foods under the law. [Hough B. Personal communication to M. Blumenthal, Apr. 27, 2005.] His company filed the lawsuit in an attempt to deter FDA’s new procedure for creating what he considered arbitrary rules which contradict the plain meaning of existing federal law (DSHEA). The American Herbal Products Association (AHPA) issued a statement on April 26 clarifying its policy on the sale of ephedra in dietary supplements.11 AHPA has notified all its members that at this time it is the organization’s policy that none of its members should be selling low doses (10 mg or less) of ephedra in dietary supplements until the FDA has clarified its position on the Court decision. At this time it is not clear whether FDA plans on appealing the decision or will implement the new policy set by the Court. The court decision does not affect the sale of the herb ephedra in traditional formulations intended for use that is consistent with traditional uses, e.g., pulmonary complaints, and are dispensed by licensed healthcare practitioners. As might be expected, court’s decision has stimulated a new round of media and congressional criticism of the relative safety of herbs and dietary supplements as well as DSHEA. For example, a highly critical article by Chris Mooney was posted on the website of the American Prospect on April 25.12 The Prospect is relatively influential in Democratic and progressive political circles in Washington. The article uses language such as the court decision is a “scandal” and a “disturbing ruling”, refers to DSHEA as “a terrible law” and a “peculiar and misguided law” and the “wrongheaded standards encoded in the DSHEA”, and repeats the often-cited media mantra about “unregulated herbal supplements” and that the “FDA has been hamstrung and effectively rendered impotent.” More information regarding the sale of ephedrine products or FDA regulations in general is available from the law offices of Rakesh M. Amin at (312) 327-3382 or rakesh@amin-law.com. References 1 21 C.F.R. Pt. 119, Final Rule Declaring Dietary Supplements Containing Ephedrine Alkaloids Adulterated Because They Present an Unreasonable Risk (Published February 11, 2004) (Effective April 12, 2004) available at /dockets/98fr/1995n-0304-nfr0001.pdf 2 Nutraceutical Corporation and Solaray, Inc. v. Lester Crawford, D.V.M., Acting Commissioner, U.S. Food and Drug Administration, et al., Case No. 2:04CV409TC, U.S. District Court for the Central District of Utah; available at gov/reports/204cv409-28.pdf
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=243) Mega H- Hydrogen (H-)The Fuel of Life
Date:
June 03, 2005 05:00 PM
Our universe is composed of millions of compounds, all derived from just 106 atoms. Of these elements, hydrogen is the first and most fundamental. Hydrogen is also the most abundant element, comprising 90% of all atoms in the cosmos. In our sun and stars, hydrogen nuclei fuse to produce helium, the second element. This generates the enormous energy that powers life on earth. And just as hydrogen fuels the sun, so, in the human body, it is the essential factor in the electrochemical process that produces ATP, the energy molecule. Virtually all the millions of biochemical processes that occur every second of our lives are powered by ATP. These facts are well established. But they are so basic that, until now, they have been overlooked in the world of nutritional science. It took the dedicated research of Dr. Patrick Flanagan to harness the power of active hydrogen for health and human development. Introducing a revolutionary breakthrough in the field of nutritional science: MEGA H-™ Active Hydrogen (H-), the Fuel of Life. The Creation of Mega H- For 30 years Dr. Patrick Flanagan’s life work has been to discover the health and longevity secrets of the Hunza people of the Himalayas. It is believed a much greater percentage of people there live past the age of 100, with far less of the diseases that ravage the West. The locals claimed that their secret was the cloudy, mineral-rich water that rushes down from the Himalayan glaciers. In studying the properties of this Hunza water, Dr. Flanagan found that silica crystals dissolved in the water were able to hold negatively charged hydrogen ions (H-). These compounds are technically called silica hydrides. This makes Hunza water a power source, filled with the same active H- that powers the human body. Typically hydrogen has one positively charged proton in the nucleus and one negatively charged electron orbiting the nucleus. The two opposite charges balance each other, resulting in no charge. Active hydrogen, on the other hand, contains two electrons orbiting the nucleus, creating a negative charge. It is this active hydrogen in its charged form that the body needs to carry out its crucial functions. Dr. Flanagan has recreated this silica hydride compound as MEGA H-™. Cellular Energy: ATP, Hydrogen and Mega H-™ ATP, adenosine triphosphate, is composed of three phosphates. The breaking of the bond between the second and third phosphates releases the energy to power virtually all cellular processes. Amazingly, we all generate enough metabolic energy to produce our own body weight in ATP every day just to function! Every second, each of our approximately 50 trillion cells consumes and regenerates 10 million molecules of ATP. This massive energy generation (ATP production) is the fundamental core function of every human cell. Without it, basic activities such as cellular repair, and protein, enzyme, hormone and neurotransmitter synthesis would not occur. DNA repair and cell reproduction would cease. Thoughts, feelings, communication, and our ability to experience the world through our senses and change it through our actions would stop. The negative implication of poor energy generation for our health and vitality levels is significant. Many factors such as aging, poor nutrition and pollution can impede this critical energy generation. Negatively charged electrons from hydrogen are the source of the energy needed to generate this staggering amount of ATP. This energy production takes place in the mitochondria of the cells at the final stage of the Krebs Cycle, called the electron transport chain. Typically, the hydrogen comes from the breakdown of carbohydrates from food, which yields hydrogen as well as carbon and oxygen. But MEGA H-™ is an alternative, electron- rich source of hydrogen to power energy generation. In fact, MEGA H-™ has been shown to double the production of ATP and NADH, according to in vitro studies. (NADH is the coenzyme form of vitamin B-3, niacin, that carries hydrogen to the production site of ATP.) If this alone was all that MEGA H-™ could accomplish, it would be the most significant nutritional compound yet discovered. But its properties go far beyond energy generation. It is the body’s most efficient and effective antioxidant. MEGA H-™ also increases cellular hydration and the uptake of nutrients into each cell by lowering the surface tension of water (making water “wetter”). And it can improve athletic performance by lowering lactic acid levels after strenuous workouts. Aging and Antioxidant Defense Energy Decline: As we age, there is a decrease in our bodies’ ability to generate cellular energy—and oxidative damage may be a primary factor. Many scientists now accept the theory of aging first proposed by noted scientist Denham Harman, M.D., Ph.D., who argued that “aging changes are induced by free radical reactions, largely initiated by the mitochondria … the rate of damage to the mitochondria determines our life span.” Why is this? While oxygen is necessary for human life, the very act of breathing generates free radicals. Our mitochondria— tiny energy production plants—are the chief source of oxidants produced in our bodies. It is believed these oxidants damage the mitochondria in which they are produced, including the inner mitochondrial membrane, which is the site of ATP production. This would seriously impair the ability of mitochondria to meet cellular energy demands. The result: signs of normal aging such as impaired memory, hearing, vision and stamina. DNA Damage: Oxidants also can damage the cell’s DNA. Hydroxyl radicals cause DNA strands to break; if breaks occur in both strands of DNA, the cell cannot repair the damage and will die. Normally, the body has mechanisms to correct or remove damaged cells. However, as we age and cellular energy production declines, the ability to correct these errors is significantly reduced. Left unrepaired, DNA errors may be passed on when cells divide. Over time, these errors can silently accumulate, leading to cellular changes that go unnoticed until body system imbalances become evident. World’s Most Elemental Antioxidant MEGA H-™ may be the world’s most powerful antioxidant. It is possible to measure the Oxidation Reduction Potential (ORP) of any compound. This rating, which measures the number of electrons present in relation to protons, ranges from (plus) +1,200 to (minus) -800 millivolts; the stronger an antioxidant is, the closer its ORP would be to -800. The more positive the ORP reading, the fewer the number of available electrons from active hydrogen. In chemistry, active hydrogen is defined as hydrogen with an extra electron, also known as the hydrogen anion, negative hydrogen or H-. The strongest natural antioxidants up until now, such as grape seed and green tea, have ORP’s of -100. But Mega H-™ has an ORP of -778 millivolts, as compared to distilled water, making it the most potent natural antioxidant available today. What’s more, MEGA H-™ is in a class by itself, compared to other antioxidants, due to its electrochemical structure. Free radi-cals—unstable molecules that are missing one or more electrons—damage cells by taking electrons from healthy molecules to balance themselves. When other antioxidants donate electrons to quench free radicals, they in turn become reactive free radicals and require electrons from other antioxidants to become stable. The new antioxidant also requires an electron to return to stability. This process continues, resulting in an inefficient and energy-consuming free radical cascade. But MEGA H-™’s negatively charged hydrogen molecule possesses two electrons instead of the typical one. This extra electron can be donated without generating the inefficient free radical cascade. Dr. Flanagan’s profound contribution was his discovery of a method for stabilizing and delivering negatively charged hydrogen (H-). Unlike taking other antioxidants, supplementing with MEGA H-™ provides a net gain of free radical-quenching electrons into the system. Additional Health Benefits MEGA H-™ has been the subject of additional positive research: Increases Cellular Hydration: Water is important to cells, interstitial fluids (surrounding joints, muscles and organs), and the matrix of blood. As the body’s primary fluid, water serves as a solvent for nutrients. Since water is used to carry nutrients into the cell, it is theorized that increased cellular hydration also increases the bioavailability of nutrients. Water also eliminates toxins and waste products from the body. From energy production to joint lubrication, all our systems depend on water. It has been theorized that aging results in cell dehydration. A study done by Gary Osborn and H. Salinas, M.D. of the Texas Institute of Functional Medicines suggests that silica hydride supplements like MEGA H-™ increase intracellular, extracellular and total body water levels. It is theorized they work by decreasing water’s surface tension, which allows water and nutrients to more easily enter cells and become available for use by the body. Assists In Exercise Recovery: During strenuous exercise, the oxygen supply to muscle cells is insufficient to meet energy demands. Muscle cells then turn to anaerobic respiration to continue to generate energy. This creates lactic acid, which diffuses into the blood, causing muscle fatigue, soreness and loss of endurance. A placebo-controlled study on six healthy males showed that blood lactate levels significantly decreased after exercise when silica hydride supplements were taken for one week before an exercise trial. The Scientist Behind Mega H-™ This revolutionary approach to nutrition and health is the brain child of Dr. Patrick Flanagan. Dr. Flanagan was a child prodigy with an intense interest in electronics, biochemistry and physics. At the age of 12, he invented a guided missile and atom bomb detector. This technology was subsequently adopted for use by the U.S. government. At 14 he developed the Neurophone®. This device transmits acoustic information to the brain by means of radio waves into the skin, byPassing the eighth cranial nerve, and may allow some deaf people to hear. By the age of 18, he was named one of the Top Ten most promising young scientists in America by Life Magazine. Dr. Flanagan’s work with MEGA H-™ has its roots in his collaboration with Dr. Henri Coanda, a respected scientist who died in 1972. Dr. Coanda passed along his investigation into Hunza water to Dr. Flanagan. MEGA H- is the culmination of decades of research to bring the energizing and anti-aging benefits of active hydrogen (H-) to the world. Mega H-™ Hydrogen (H-)The Fuel of Life MEGA H-™ is the first supplement available in the natural foods industry to provide a large reservoir of freely available electrons to power the body’s diverse energy functions.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=169) Inflama Rest - Natural COX-2 Inhibitor for Joint Comfort
Date:
June 02, 2005 12:37 PM
It happens. You reach for something and feel a sudden discomfort. Your joints and muscles may feel tender from overuse. Inside, your cellular systems are out of alignment, resulting in lessened mobility. Source Naturals understands how difficult joint discomfort can be to live with. We are deeply committed to developing well-researched formulas that address the root cause of joint distress. Our Bio-Aligned Formulas™ bring alignment to multiple interdependent body systems. Only this type of indepth formulation can provide the long-term relief you are looking for. Regain your comfort with Source Naturals INFLAMA-REST. Unlike many products that contain just a few ingredients to offer temporary relief, INFLAMA-REST is a Bio-Aligned Formula™, scientifically designed to address aches. INFLAMA-REST goes deep to the underlying cause of joint discomfort. These systems include: inhibition of pathways involved in joint discomfort, joint and muscle function, DNA protection and antioxidant defense. Addressing Joint Comfort on a Deep Cellular Level Discomfort can come from many places. From your head to your toes there are many tissues that can become uncomfortable from everyday use. Joint discomfort starts when stress, such as tissue damage, causes an imbalance of the biochemical pathways on a deep cellular level. The body has its own “innate intelligence” encomPassing more than just the thoughts in the brain. It consists of ongoing and complex chemical reactions regulated by a wide variety of enzymes and chemical messengers. These reactions can sometimes get out of balance – but you can control and inhibit key body chemicals that would otherwise lead to cellular irritation. For example, certain types of prostaglandins that regulate normal physiological functions such as blood flow, are maintained at low levels in all our cells under everyday conditions. In response to stress, a message is sent to the outer membranes of certain cells to convert their fatty acids into arachidonic acid, the raw material for prostaglandins. This stress also directs cells to produce Cyclooxygenase enzyme- 2 or COX-2. This enzyme converts arachidonic acid into Prostaglandin E2, a particular type of prostaglandin specifically responsible for irritation on a cellular level. The result: joint discomfort. But that doesn’t have to happen. By supporting inhibition of the culprit COX-2, you can decrease Prostaglandin E2 production to bring your joint tissues back into a healthy and comfortable balance. INFLAMA-REST includes herbs that support inhibition of COX-2 in a variety of pathways. Ginger, turmeric and green tea all support direct COX-2 inhibition. But there are other places in our biochemical communication system where COX-2 production can be inhibited. Two additional factors that lead to COX-2 production are nitric oxide and the enzyme that produces it, nitric oxide synthase (iNOS). Nitric oxide is a free radical associated with cell growth and regeneration, blood vessel elasticity and COX-2 enzyme production. Resveratrol, rosemary and turmeric support iNOS inhibition, thus inhibiting your body’s over-production of nitric oxide and the COX-2 enzyme. A related irritation factor is also one of the latest scientific discoveries in cellular health - Nuclear Factor kappa-B (NF-kappa-B). NF-kappa-B works at the DNA level – at the blueprints of cells. When activated, this factor controls the genes that regulate cell growth, differentiation and regeneration. And blocking this factor is also associated with inhibition of both COX-2 and iNOS enzymes. Stinging nettle, milk thistle and Chinese Skullcap all block unhealthy NF-kappa-B activation in your body and thereby help support COX-2 inhibition. Cytokine Inhibition Compounds called cytokines, or interleukins, can also stimulate biochemical pathways leading to joint discomfort. Cytokines are chemical messengers produced by the immune system to regulate defensive activity when they are stimulated. For example, cytokines are released by macrophages in response to stimuli such as tissue damage. This results in rapid escalation and amplification of cell number and response. Constant stress can shift this system out of balance, resulting in tissue discomfort. Bringing these compounds back into balance can preserve your short-term comfort and longterm health. INFLAMA-REST contains curcumin from the spice turmeric. Curcumin assists the body’s inhibition of cytokine activity to support reduced cellular irritation. And Bioperine®, which is derived from black peppercorns, is added to assist curcumin assimilation. Stress Response: Joints and Muscle Support Inhibition of chemical messengers involved in joint discomfort is just part of a Bio-Aligned strategy for relieving discomfort. Research has shown that emotional stress, particularly long-term, can directly affect the body and set in motion mechanisms that cause physical discomfort. Ashwaganda and Chinese Skullcap (S. baicalensis) are herbs that help modulate the body’s response to stress and may help ease aches and discomfort. Boswellia, ginger, quercetin, milk thistle, feverfew, Oregon grape root and bromelain (an enzyme found in pineapples) provide additional soothing relief to your cells and tissues. Essential nutrients are also vital to maintaining your joint comfort. The tocotrienol forms of vitamin E, along with selenium, protect cell membranes from lipid-based free radicals. Magnesium aids energy metabolism in muscles and can reduce tenderness as well as muscle spasms. Zinc is essential for normal cellular repair mechanisms such as wound healing and is important for the growth and maintenance of connective tissue. And manganese works to protect cells from oxidation and to build healthy connective tissue as well, an essential component of healthy joints and muscles. Protecting Your DNA To reduce cellular irritation, you need to protect the DNA in your cells. DNA is the blueprint for all of the molecules in the body. If your DNA is altered or damaged, then needed molecules may not be produced, leading to short-term and eventually long-term damage. Curcumin, from turmeric, has been shown in in-vitro studies to protect DNA against strand breakage. Quercetin has also been shown to directly protect DNA against strand breakage and base oxidation from free radicals and damaging chemicals, according to recent in-vitro research. Providing Powerful Antioxidant Cellular Protection Antioxidants are selfless bodyguards of your cells. They donate their own electrons to stabilize free radicals in your body. Thus, antioxidants absorb the damage that would have been done to your tissues. Some regulatory chemicals, such as Nitric oxide, are powerful free radicals and oxidants. Oxidants also activate NF-kappa-B. Tissues, lipids, proteins and DNA are extremely sensitive to oxidation. Quercetin, milk thistle, turmeric, ginger, rosemary, vitamin E and resveratrol are all antioxidants that help modulate the activity of these compounds as well as protect cells and tissues from damage. Plus, Superoxide Dismutase (SOD), one of the most important enzyme antioxidants found in your body, has been added in a new cutting-edge form. The vegetarian SOD used in INFLAMA-REST is attached to Gliadin, a wheat protein, that has demonstrated significantly better absorption than SOD alone. Six Lifestyle Strategies for Fewer Aches
Inhibition of COX-2: Turmeric, Ginger, Chinese Skullcap, Green Tea, Resveratrol, Boswellia, Silymarin, White Willow Inhibition of Cytokine Turmeric, Stinging Nettle, Feverfew Inhibition of Rosemary, Green Tea, Resveratrol, Turmeric, Quercetin, Chinese Skullcap NF-kappa-B Activation Silymarin, Chinese Skullcap, Stinging Nettle, Rosemary, Resveratrol Stress Response: Ashwaganda, Magnesium, Chinese Skullcap, Oregon Grape, Feverfew, White Willow DNA Protection Turmeric, Quercetin, Rosemary Antioxidant Defense Silymarin, SOD Gliadin, Turmeric, Rosemary, Tocotrienols, Resveratrol, Ginger, Selenium, Manganese, Zinc Prostaglandin & Leukotrine Synthesis Joint & Muscle Support Inhibition of Nitric Oxide Synthesis Production
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=158) KudZu, Treatment of alcohol dependence or alcohol abuse
Date:
May 19, 2005 09:29 AM
For millennia, folk medicines have been used to treat ‘‘alcohol addiction’’ in China. A thorough literature search of the ancient Chinese pharmacopoeias revealed a long list of traditional remedies, including the 16 ‘‘stop-drinking’’ formulae of Sun Simiao (ca. 600 AD) and the ‘‘anti-alcohol addiction’’ formula of Li Dongyuan (ca. 1200 AD), 2 of the most reputed ‘‘medical doctors’’ in the history of Traditional Chinese Medicine. However, like those discovered by the ancient Romans,11 most of the ancient Chinese remedies for ‘‘alcohol addiction’’ were based on psychological aversion: to deter patients from further drinking by associating alcohol drinking with an unpleasant experience. Interestingly, as time went by, treatments based solely on psychological aversion were gradually eliminated from the ancient Chinese pharmacopoeias, presumably because of their ineffectiveness and/or undesirable side effects. The only remedies that have survived this historical trial-anderror scrutiny are those consisting the root (Radix puerariae, RP) or flower (Flos puerariae, FP) of Pueraria lobata (a medicinal plant known to the West as kudzu). It was on the basis of this historical backdrop, we initiated the search of safe and efficacious anti-dipsotropic (alcohol intake suppressive) agents from RP. This approach has led to the discovery of daidzin,12 an isoflavone that has since been shown to reduce alcohol drinking in all alcohol preferring animal models tested to date.
Alcohol abuseAlcohol abuse and alcohol dependence (i.e., alcoholism) are serious public health problems of modern society. In the United States alone, an estimated 13 million adults exhibit symptoms of alcohol dependence due to excessive alcohol intake, and an additional 7 million abuse alcohol without showing symptoms of dependence according to U.S. Government projections from studies conducted in the mid-1980s. Alcohol dependence and abuse are very expensive: in economic and medical terms, it will cost the U.S. well over $200 billion in 1991 with no prospect of falling or leveling off. The social and psychological damages inflicted on individuals as a consequence of alcohol abuse, e.g., children born with fetal alcohol syndrome (FAS) and victims of alcohol-related accidental death, homicide, suicide, etc., are immense. While it is generally accepted that alcoholism and alcohol abuse are afflictions with staggering international economic, social, medical, and psychological repercussions, success in preventing or otherwise ameliorating the consequences of these problems has been an elusive goal. Only very recently the public view that alcoholism and alcohol abuse are remediable solely by moral imperatives has been changed to include an awareness of alcoholism and alcohol abuse as physiological aberrations whose etiology may be understood and for which therapy may be found through scientific pursuits. Both alcohol abuse and dependence arise as a result of different, complex, and as yet incompletely understood processes. At present, alcohol research is in the mainstream of scientific efforts. Our studies on alcohol (ethanol or ethyl alcohol) have been based on the hypothesis that its abuse can ultimately be understood and dealt with at the molecular level. Such a molecular understanding, if achieved, would provide a basis for the identification and development of appropriate therapeutic agents. Our view hypothesizes that the clinical manifestations of alcoholism and alcohol abuse are the consequence of aberrations or defects within one or more metabolic pathways, affected by the presence of ethyl alcohol. In order to test this hypothesis, our initial studies focused on physical, chemical, and enzymatic properties of human alcohol dehydrogenase (ADH), the enzyme that catalyzes alcohol oxidation according to the following reaction formula: CH.sub.3 CH.sub.2 OH+NAD.sup.+ .fwdarw.CH.sub.3 CHO+NADH In addition, our studies more recently have focused on the aldehyde dehydrogenases (ALDH) which catalyze the subsequent step in the major pathway of ethanol metabolism according to the following reaction formula: CH.sub.3 CHO+NAD.sup.+ .fwdarw.CH.sub.3 COOH+NADH Prior to our research (for example, see Blair and Vallee, 1966, Biochemistry 5:2026-2034), ADH in man was thought to exist in but one or two forms, primarily in the liver, where it was considered the exclusive enzyme for the metabolism of ethanol. Currently, four different classes of ADH encomPassing over twenty ADH isozymes have been identified and isolated from human tissues. There is no reason to believe that all of these ADH isozymes are necessary to catalyze the metabolism of a single molecule, ethanol, even though all of them can interact with it. We have proposed that the normal function of these isozymes is to metabolize other types of alcohols that participate in critical, physiologically important processes, and that ethanol interferes with their function (Vallee, 1966, Therapeutic Notes 14:71-74). Further, we predicted that individual differences in alcohol tolerance might well be based on both qualitative and quantitative differences in isozyme endowment (Vallee, 1966, supra).
Our research has established the structures, properties, tissue distribution, and developmental changes for most of the ADH isozymes, which while structurally quite similar, and presumed to have evolved from a common precursor, are functionally remarkably varied. Of the more than 120 publications from our laboratory that relate to the above subjects, the following, arranged in six categories, are especially useful for instruction in the prior art.
Kudzu Recovery 60ctKudzu Recovery 120ct
Kudzu Root Extract 50capsKudzu Root Extract from Solaray 60ct
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