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The Health-Supporting Properties of Curcumin
September 14, 2022 11:19 AM
Curcumin, the active polyphenolic extract of turmeric, is one of the most scientifically investigated plant compounds. Curcumin's health-supporting properties depend on its bioavailability. NOW Curcumin Phytosome is a unique form of curcumin complexed with Phosphatidylcholine that clinically demonstrates enhanced absorption and bioavailability as compared with standard curcumin extracts. Clinical studies also show that curcumin phytosome is a powerful free radical scavenger, can help to support a balanced immune system response to normal metabolic stress, and can promote healthy joint mobility and flexibility.
The Benefits of Curcumin
Curcumin has been shown to offer a wide range of health benefits, thanks to its potent antioxidant and anti-inflammatory properties.* Some of the ways in which curcumin supports health include:
Brain Health: Curcumin has been shown to promote cognitive function and healthy brain aging.* It does this by reducing inflammation and oxidative stress, two factors that are known to contribute to age-related cognitive decline.*
Heart Health: Curcumin has been shown to support cardiovascular health by helping to maintain healthy cholesterol levels already within the normal range.* It also promotes healthy blood vessel function.*
Digestive Health: Curcuin supports a healthy inflammatory response in the digestive tract.* This helps to keep the gut lining healthy and promote regularity.*
In conclusion, curcumin is a powerhouse compound with numerous health-supporting properties. Thanks to its unique formulation as a complex with Phosphatidylcholine, NOW Curcumin Phytosome is one of the most bioavailable forms of curcumin on the market today. If you're looking for a supplement to support brain, heart, and digestive health, look no further than curcumin phytosome!*
Omega-3s are a potent way to treat depression without resorting todangerous prescription medications
May 17, 2019 04:01 PM
One can treat poor mood and depression without using pharmaceutical drugs. One of these approaches involves using omega-3 fatty acid. Foods rich in this fatty acid can help. It has been shown by many scientific studies that the risk of having depression is reduced when one takes foods rich in omega-3 fatty acid. Some of the means that have been identified as the pathways in which omega-3 fatty acids work is that they can make the CNS to release more serotonin, they can reduce the risk of an inflammation and also its severity, and they can stop phosphatidyl-inositol from releasing hormones that make a person to have depressive moods. The way omega-3 fatty acids do this has been found to be similar to the way anti-depressant drugs work. Omega-3 fatty acids have been found to counter the release of serotonin in the brain that trigger depressive moods and they also have effect on the release of cytokines in the heart that relates to lowering the risk of one having coronary heart disease. And fortunately, heart disease is linked to major depressive moods. So, omega-3 fatty acid is a powerful compound that can be used to treat both problems. But what researchers have not agreed upon though is the required dosage of omega-3 fatty acid that a person should take each day to reap these benefits.
"The fatty acids achieve their natural antidepressant effects through several means. Omega-3s can raise the activity of CNS seratonin, reduce the risk and severity of inflammation, and stop phosphatidyl-inositol from sending signals that bring about depressive moods."
Read more: https://www.naturalnews.com/2019-04-15-omega-3s-are-a-potent-way-to-treat-depression.html
Emerging research finds inositol to be an effective treatment forpanic disorder
March 15, 2019 10:44 AM
Inositol is another name for vitamin B8, and it is showing to be highly effective in the treatment of panic disorder. Taking doses of approximately 20 grams per day has shown to reduce both the frequency and severity of panic attacks that those with the disorder experience. In a recent study, inositol was shown to be just as effective as fluvoxamine in treating panic disorder. Inositol has also shown to help in treating Obsessive Compulsive Disorder (OCD).
"However, based on the results of study, a type of sugar called inositol could be used to reduce the frequency of these panic attacks."
Read more: https://www.naturalnews.com/2019-01-19-inositol-for-panic-disorder.html
Heart Disease and Poor Gut Health Go Hand In Hand
December 07, 2016 02:59 PM
A new mechanism has been discovered that connects Phosphatidyl choline (also called lecithin), a common dietary fat, along with intestinal microflora, to an increased risk of heart disease. The study shows that the heart risk of people with a diet high in the lipid depends on how the micro-organisms that live in their digestive tracts metabolize it. When lecithin and choline were fed to mice, the substances were converted to a heart disease-forming product by the intestinal microbes. In humans, higher blood levels of choline and the heart disease forming microorganism products are strongly associated with increased cardiovascular disease risk.
"Finding Balance: Empower Yourself with Tools to Combat Stress and Illness,” discuss heart disease and stomach bugs, and how the bacteria in your gut affects your health."
How Does Silymarin Protect the Liver?
September 05, 2015 07:45 AM
For thousands of years, the flowering herb milk thistle has been used as a natural remedy for many different ailments, including liver problems. The herb is still widely used today – in fact, the University of Maryland Medical Center reports that several scientific studies have shown that milk thistle helps protect the liver from toxins and may provide many other benefits.
How Does Milk Thistle/Silymarin Help the Liver?
So how does this ancient Mediterranean herb help treat present-day liver disorders? The seeds of milk thistle contain silymarin, a powerful bioflavonoid complex. Silymarin is actually comprised of three different flavonoids: silybin, silydianin and silychristin. Working together, these flavonoids provide antioxidant properties that are believed to help repair damaged liver cells by generating the growth of new ones. These reparative properties make silymarin particularly useful at treating liver damage conditions such as cirrhosis.
For example: in a clinical trial of patients suffering from cirrhosis of the liver, some were treated with daily doses of oral silymarin while a control group was given a placebo. After four years of treatment, the study found that those patients who were given silymarin had a significantly higher survival rate as compared with those treated with the placebo.
In addition to supplying a concentrated boost of antioxidants, silymarin also has anti-inflammation properties which may be helpful in treating hepatitis or general liver inflammation.
How to Take Silymarin
Once silymarin is extracted from milk thistle seeds, it may be taken in a few different forms: Capsule, Liquid form, and Silymarin Phosphatidylcholine complex.
The silynmarin Phosphatidylcholine complex may offer added liver protection benefits. Studies have shown that it may be easier for the body to absorb than the form from ordinary milk thistle seed extract. This is because Phosphatidylcholine helps the silymarin attach to cell membranes, which may block harmful toxins from entering the liver.
Phosphatidyl Serine is Good For Memory improvment
March 23, 2014 06:05 PM
In order to remember things in a proper order and to have sharp memory, brain uses a lot of chemicals for its functioning. Out of all these chemicals Phosphatidyl serine is one of the most important chemicals for better memory. Although body can make this chemical by itself, but it gets most of this chemical from food only.
Effects of Phosphatidyl serine
If we talk about the effect of Phosphatidyl serine on memory, doctors use this chemical to against Alzheimer disease. Also, doctors recommend the same chemical as a medicine for those old people that stay in confusion or lose their capability of remembering things for a longer time. Also, many experts believe that if people will use this chemical as a supplement then it can help them to get a better memory.
Talking about the base of these beliefs, many studies found that Phosphatidylserine is highly effective on memory enhancement and all the researches received only positive result from it. In these researches experts and researchers found that all those people or animal that used Phosphatidyl serine had great visible improvement in their memory.
In case you are wondering about the side effects of this chemical, then it is safe for everyone and researchers did not find any kind of side effect on people after its consumption. In order to make sure they get accurate results about its side effect, they did an extensive experiment study of six months and they found that it is safe to use for any person.
So, we can say that Phosphatidyl serine is highly effective in the improvement of memory and if you are planning to take this chemical for your memory improvement, you can easily take it. However, you need to make sure that you buy it from a manufacture that is known to provide high quality medicine and supplements and has a good reputation among all the experts of related field.
Supplements That Can Improve Focus
March 23, 2014 07:57 AM
A focused mind is one that is able to concentrate on a particular issue and think about it, discuss it or deal with it and pay special attention to that subject. This explains why people have different focus abilities as brought about by their varying environments and capabilities. Enhanced minds quickly grasp ideas as opposed to low minded ones. A determined mind therefore understands and interpret facts more readily in an effective way, and this is why it is important for individuals to to be focused at school. However, there are instances where learners have limited focus abilities, but this can be improved by use of focus supplements. The following are the supplements that can be used to boost an individual's focus levels.
Supplement that can help improve focus
Various health Benefits of lecithin
December 22, 2013 04:45 PM
What is Lecithin
When we talk about fat, most of us presume that this is not good for health and we should avoid all kind of fat to heave a healthy life. However, this is not true because fat substances are essential for healthy body and Lecithin is one of those important fat substances that make sure your body remains healthy and protected from a variety of problems.
Talking about the Lecithin it is a specific fat that is commonly known phospholipids that is available in every cell of human body. This phospholipid is responsible for maintenance of cell membrane structure and if Lecithin goes below the required amount, then cell membrane may not perform properly and it may not protect or nourish the cell.
Benefits of Lecithin
If we talk about all the benefits of Lecithin, we can make a long list of all the benefits of this particular fat substance. However, improvement in brain function, healthy weight loss, reducing of cholesterol level, increasing of liver health, and prevention of various diseases are few of the most important benefits of Lecithin.
In order to improve the function of brain Lecithin break down the Phosphatidylcholine into choline that is well known for prevention of memory loss. Talking about the weight loss effect, it emulsifies the fat in a very natural way that makes it a healthy weight loss solution as well. Other than this it also help the blood stream to absorb the nutrients from body that give extra energy to body and a person can do more exercise so he can reduce the weight and can get into shape.In addition to this it can detoxify all the harmful elements as well from your body that give extra strength to your liver and you get a better and healthy body along with a strong and healthy liver.
What Is Solaray Phosphatidyl Serine?
January 04, 2013 01:00 PM
Phosphatidyl Serine : What are its Health Benefits?
Phosphatidyl serine is a popular medication for people who need to improve their memory and mental well-being. Not only does it work to improve your memory, it also has other health benefits to your body.
What is Phosphatidyl serine?
Each cell in your body has a membrane that protects its internal contents from the surrounding environment as well as control what enters the cell and what goes out. This serine is one of four major phospholipids that make up part of this membrane. This lipid is found in high concentrations in the cell membrane that surrounds the hippocampus of the brain, which is associated with your memory.
How does Phosphatidyl serine supplementation benefit you?
As you age, the cells around the hippocampus also lose their potential to fully function. This makes your mental processes to slow down. Providing your body with this serine will provide material necessary to rejuvenate the cell membrane, thus improving your memory. This compound is useful in stressful situations. Some situations need you to concentrate on what you are doing and yet you may be tired.
For example, you may face an exam which needs you to be at full concentration and be alert at all times. This serine helps boost your memory and concentration, which in turn increases your focus thus improve learning. When you get stressed, your body releases cortisol which damages the tissues of the hypothalamus in your brain. To reduce the effects of this hormone, you need Phosphatidyl serine to repair the tissues that have been damaged. This helps you to retain your memory after a stressful situation.
For your body to function properly, the cell membrane surrounding various organs has to be in good health. Phosphatidyl serine will work to improve the health of various membranes, such as myelin sheaths found in the central nervous system. The compound is found in small amounts in foods such as liver and soy, therefore it is advisable to use supplements which provide a high level of the compound.
What Are The Health Benefits Of DMAE?
April 26, 2012 12:57 PM
Dimethylaminoethanol or DMAE is anorganic compound that is metabolically produced by the adrenal glands, testes and the brain in small quantities. It is converted into testosterone, estrogen and cortisone by the body. It is a known fact that the liver processes DMAE into choline, but the molecule thus produced is charged and cannot break the blood-brain barrier. Studies have shown that DMAE methylated in the brain acts as the precursor for the manufacture of acetylcholine, a neurotransmitter that plays a key role in the conduction of signals in the brain as well as the nervous system.
DMAE also stimulates Phosphatidylcholine, a crucial part of cell membranes. However, the DMAE naturally produced by the body is sufficient only to maintain healthy brain and functions. It will not improve their functions. Though DMAE is found in fish such as salmon, anchovies, and sardines, supplementation in the pill form is important because of the practical difficulties having these foods in the right form and quantity on a daily basis to derive the benefits. DMAE supplements for oral consumption are through stores that sell health foods and groceries.
Daily consumption of DMAE in the supplement form provides a number of benefits to the body. Some of the benefits are as follows:
It helps prevent as well as treat cardiovascular problems and boost the body's immune system because of its strong antioxidant properties.It protects cells from the harmful effects of free-radicals by helping them retain the nutrients that are essential and expelling waste.As a precursor in the production of the neurotransmitter acetylcholine, it supports the functioning of the brain in a number of ways. It increases a person's attention span, relieves behavioral problems and hyperactivity or attention deficit hyperactivity disorder. It is also helpful in treating memory lapses and Alzheimer's disease.
It helps stop production of arachidonic acid which is responsible for wrinkling and aging of skin. Topical creams containing DMAE help tighten skin and reduce wrinkles and fine lines.It is found to be effective in burning fat because of its involvement in the production of acetylcholine. It increases the metabolism in the body because of its thermogenic effect.It can be beneficial as an anti-inflammatory as well.It can reduce the amount of sleep required for a person by up to one hour.It can safely be used as a substitute for anabolic steroids.
Research studies have shown that consumption of 200 to 500 mg of DMAE on a daily basis is helpful in improving health. However, it is important to start with a low dosage of DMAE and then gradually increase the dosage level to the optimum level. Higher dosage can cause headaches, insomnia and muscle tension. People suffering from conditions such as schizophrenia, mental depression and epilepsy should not have DMAE supplements. Pregnant and lactating women also should not have DMAE.
Summarizing, consumption of recommended amounts of DMAE is believed to be safe. Side effects due to consumption of DMAE are rare and not generally serious. However, it is important to use high-quality supplements in order to increase DMAE levels in the body and reap the benefits.
How Does Phosphatidyl Serine Improve Your Health?
April 17, 2012 07:22 AM
Health Benefits Of Phosphatidyl Serine
Phosphatidyl serine is phospholipid that is vital to your brain functioning. The phospholipid are molecules containing both fatty acids and amino acids found in every cell in the body. Phodphatidyl Serine supplements are plant extracts that has been proven safe and effective therapeutic substance in remedying memory disorders as well as in enhancing higher brain functions. Clinical trials have shown that this vitamin supplement do strengthen your memory, increase mental acuity, increase concentration, boosts learning, enhances attention and vigilance. In addition, Phodphatidyl serine relieves depression while improving your mood and inhibits increases in cortisol induced by exercise and stress.
The supplement works by enabling your brain cells to metabolize glucose and releases it to bind with neurotransmitters which hence support learning, memory and other cognitive functions. Phodphatidyl serine enhances the cells communication in the brain through increasing the number of membrane receptor sites. It is also important to note that this natural supplement modulates the fluidity of the cell membranes which are essential in supporting the ability of brain cells to send and receive chemical communications.
Another health benefit associated with Phodphatidyl serine is its ability to restore the supply and output of acetylcholine in the brain. Acetylcholine is an essential transmitter to memory and is associated in reversing aging. Further, it increases the availability of endogenous chlorine used for de novo synthesis and production. Patients diagnosed with clinical depression that have ben put under the treatment of Phodphatidyl serine have registered a remarkable improvement with their symptoms. This follows from the fact that the supplement stimulates the production of dopamine by the brain. A deficit in dopamine in the brain has also been associated with attention deficit disorder and hence the natural supplement of Phodphatidyl serine has demonstrated to be an effective remedy for the disorder.
Research indicates that athletes involved in weight training, endurance running and cycling can reduce muscle soreness when they use Phodphatidyl serine. The athletes on this supplement have also been reported to undergo speed recovery during their rigorous training sessions. Other benefits of the supplement include; testicular function, formation of bone matrix, heart beat coordination, cell repair and removal by the immune system and secretion of hormones by the adrenal glands.
It is vital to note that phodphatidyl serine is present in almost every cell in our body and the membrane proteins it activates are important in all these cells. However, our bodies cannot produce enough amounts of it when under stress, when there is a deficit in necessary enzymes and metabolic cofactors, and when aged. Stress increases the demands for phospatidylserine thus depleting the available levels in the cells. On the other hand, aging not only increases the brain's requirement for Phosphatidylserine but also leads to inefficiency in the digestive and metabolic functions of the body. This makes it difficult for aged people to acquire enough of it from the diet and thus it is recommended that aged people should use Phosphatidyl serine supplements.
Modern diets with low fat and low cholesterol levels have been shown to be lacking in phodphotidyl serine to levels of up to 150 mg per day. A vegetarian diet on the other hand may have a deficit of up to 250 mg per day. This deficit in supply of Phodphatidyl serine in the diet leads to impairment of your brain's ability to form, store, process and even remember. It is vital hence to consider taking vitamin supplements with Phosphatidyl serine to cater for the deficit which may be detrimental to your health.
Lecithin And Its Brain Boosting Properties
March 02, 2012 07:10 AM
Lecithin is a group of fatty substances, which occur in the tissues of plants and animals. It composed of fatty acids, choline, phosphoric acid, triglycerides, glycolipids, B vitamins, glycerol, and phospholipids. Liver produces this substance daily if you follow a complete nutritional diet. Lecithin is also inevitable for all cells in your body,protecting your cells from oxidation, and it is a major building block of cell membranes. It also supports the circulatory system of your body because it is a fat emulsifier too.
The first isolation of lecithin was done by a French pharmacist and chemist, Theodore Gobley in 1846 and he named Phosphatidylcholine Lechithine in 1850. He isolated it originally from egg yolk. Today, lecithin can very easily be extracted mechanically or chemically from soybean, grape seed, and sunflower. However, in plants, the most common source of lecithin is soybean. This substance is used for medicinal purposes and as a food supplement. Sometimes, it is used as an emulsifier in cooking for preventing sticking.
Your body gets adequate amount of lecithin from your diet because it is naturally found in foods such as soybeans, egg yolk, peanuts, yeast, legumes, fish, wheat germ, grains, etc. It is also available in the market in the form of capsules, granules, and powder. This is also used as a supplement for promoting weight loss. Besides, you can also take lecithin in the form of pill or mixed in health shakes.
Health benefits of lecithin
It is believed that lecithin is beneficial for solving a number of health problems. So it is effective for:
* Cell communication,
Brain Boosting Properties of Lecithin
The major brain chemical for improving memory is acetycholine and the deficiency of this chemical is the major cause of declining memory. This chemical can be derived from nutrient choline. Fish is a rich source of acetylcholine. It can also be obtained from eggs, nuts, peanuts, soy beans, liver, etc. Eating more egg is beneficial for enhancing your memory.
There are lots of studies has been conducted for finding the effectiveness of lecithin in improving the memory. As per the findings of experts, lecithin is highly effective for improving concentration, memory, and for preventing Alzheimer's disease and maniac depression (bipolar disorder). Lecithin helps to run your brain smoothly by improving insulation around the nerves. A major part of cell membranes consists of lecithin and it is essential for the proper functioning and growth of nerve. Organ meats and egg yolks are rich sources of lecithin but the usage of these products is very less due to the fear of cholesterol. Experts think that this is the major reason for the increase of concentration and memory problems.
If you use lecithin properly, you can improve your concentration, memory, mind and nerves.
What Are the Health Benefits of Phosphatidyl Serine
February 21, 2012 07:53 AM
Phosphatidyl Serine is a phospholipid produced by the brain that brings about a number of beneficial effects to the human body. It is found in every cell of the body but it is abundantly available in the brain. Though it is manufactured naturally in the brain, this type of fat can also be derived from meat, vegetables, dairy products and supplements. In fact, lots of Phosphatidyl Serine supplements are offered on the market today because of its helpful benefits to the human body. So what are the health benefits of Phosphatidyl Serine?
Basically, Phosphatidyl Serine is a powerful nutrient that improves the cardiovascular and overall fitness and boosts the cognitive function of an individual. It increases one's mental clarity, focus, concentration and alertness. Phosphatidyl Serine is actually considered as ‘brain food' that nourishes and enhances the functions of the brain even at an old age. Intake of Phosphatidyl Serine can significantly reduce the individual's risk of suffering from life threatening diseases. In fact, clinical studies show that Phosphatidyl Serine contains powerful components that prevent an individual from developing hypertension and treat atherosclerosis.
Phosphatidyl Serine and Memory
Phosphatidyl Serine is also proven to be effective in boosting the cognitive function of the user. Studies show that the phospholipid can significantly enhance the focus and concentration of an individual. Furthermore, it improves one's learning abilities and helps in alleviating the symptoms of age-related memory loss. This type of fat regulates the production and release of neurotransmitters in the brain. Phosphatidyl Serine is also effective in preventing the development of dementia and treating it.
Studies show that production of Phosphatidyl Serine in the brain decreases with age. This results to the increased occurrence of age-related memory problems as one gets older. Phosphatidyl Serine is even effective in treating the symptoms of Alzheimer's disease that is mainly triggered by a disruption in the normal functioning in the part of the brain that controls memory, thought and language. Intake of 300g of Phosphatidyl Serine daily for two months can reduce the symptoms of the debilitating condition.
Some studies revealed that Phosphatidyl Serine has the ultimate capacity to boost the health of the cell membranes and lower the level of stress hormone in the body. This substance is also believed to be effective in reducing the impact of stress to an individual. Phosphatidyl Serine combats exercise-induced stress by reducing the level of cortisol produced by the adrenal glands during stressful situations.
A clinical study in 1990 shows that intake of Phosphatidyl Serine can significantly reduce the symptoms of depression in elderly women. Researchers claimed that depression is mainly triggered by chemical imbalances in the brain or a stressful event such as accidents and death of a spouse, children and relatives. By mitigating the impact of stress, Phosphatidyl Serine prevents the occurrence of the debilitating symptoms of depression.
Phosphatidyl Serine is also beneficial in building muscles during workout and endurance trainings. It dramatically increases the recovery time of the muscle builders between workouts. It reduces muscle soreness during workouts and increases the physical performance of an individual.
Some researchers claim that Phosphatidyl Serine can help children who have been diagnosed with ADHD. Furthermore, the substance is believed to be effective in regulating the mood of the user.
What Makes Curamed such a good Pain Remedy?
October 24, 2011 08:24 AM
Curamed And Pain (Inflammation)Curamed is an herbal supplement primarily used as a pain relief treatment. This product is a combination of many herbs which has anti - inflammatory properties. In addition, this supplement which is a blend of many herbs is also useful in enhancing the defense mechanism of the body against harmful microorganisms and illnesses. And not to mention, Curamed also contains powerful antioxidants to help protect the body from free radical damage.
Many users have reported that Curamed is effective as a pain remedy. Clinically, Curamed is approximately equal to 4,000 milligrams of curcumin and 85,000 milligrams of turmeric. Turmeric is a pepper - like herb which has a bitter taste but mild aroma. This herb is commonly used since the ancient times as a home remedy for pain. The mechanism of action of this herb is said to be because of its ability to reduce inflammation thus reducing swelling and pain sensation. Clinical studies showed that the substance in turmeric is called curcumin. This is the chemical substance in the herb which has a strong anti – inflammatory property. It can even relieve swelling and pain during osteoarthritis and rheumatoid arthritis attacks. The anti –inflammatory effect of curcumin has been compared to that of the common and effective anti -inflammatory drugs such as hydrocortisone and phenylbutazone. The good thing is that though they may have similar actions, curcumin does not have the toxic effects associated with those drugs such as ulcer formation, leucopenia and intestinal bleeding.
Curamed supplement contains proprietary complex which can provide an enhanced bioavailability and constant retention time inside the body. It is formulated using a distinctive and patented process so that it can deliver the anti – inflammatory ingredient curcumin to the body 1000%. The patented process also allows the chemicals to be inside the body for about 8 to 12 hours. Curamed is clinically studied and proven with the help of intensive research. In addition, Curamed has also been found to be an effective liver detoxifier and protectant.
Other ingredients containing the Curamed supplement include triglycerides, glycerin Phosphatidylcholine lecithin, purified water and beeswax. It contains only natural ingredients and has no sugar therefore it is safe for diabetic patients and those who are under weight loss programs. It also contains no salt and gluten making it safe for cardiovascular disease and Celiac disease patients, respectively. Each product container contains 30, 60 or 120 750 milligram – soft gel. It is made available in health food stores, drug stores and even Online. Make sure to check labels before purchasing since there are many imitations and fraud.
Recommended dosage depends on the individual’s age, gender, pain threshold, health condition and other related factors. The recommended dosage is usually one to two soft gels everyday. Give Curamed a try and feel the difference!
Phosphatidyl choline, Aging, And Intelligence What You Must Know
May 24, 2011 10:52 AM
If you are aging and wish to maintain your intelligence, experts are turning to the belief that a supplement of Phosphatidylcholine could enable you to do this. For a long time, lecithin supplements have been recommended to people seeking a way to maintain their faculties as they age, and in a number of cases it appears to have been effective. Now it is Phosphatidylcholine that is being recommended, and it is certainly no coincidence that this phospholipid/choline combination constitutes the bulk of lecithin.
Nor is it any coincidence that the cell membranes of the brain and everywhere else in your body contains large quantities of Phosphatidylcholine, or at least should do for maximum effectiveness. The membranes of the brain cells of a young infant consist of around 90% of this phospholipid, while those of the brain cells of a 60 -70 year old contain only around 10%. This figure will naturally vary with each person, and some individuals could have a considerably higher amount and others less, but that is a rough average.
It follows, then, and many experts agree, that by taking a supplement of Phosphatidylcholine you can slow down the natural loss of cognitive ability, memory and overall brain function. If taken according to the recommended doses there are no significant side effects, so what do you have to lose? Certainly not your memory and your ability to make that decision because you are going to lose that in any case - unless these experts are correct in their thinking and you take their advice.
Did You Know Lecithin is More than a Brain Food
February 15, 2011 04:16 PM
Lecithin, first discovered as the yellow substance in egg yolk, is now associated with a wide array of health benefits. It is in fact made up of a number of naturally occurring substances that all play an important role in promoting overall health at the right amounts. Today lecithin is made available as over-the-counter supplements and utilized for many different purposes in the food industry.
Lecithin has been proven to reduce cholesterol serum levels. For one, it has a direct effect on the digestion of triglycerides and cholesterol from the foods we eat, blocking the pathway that breaks down fats into smaller particles and their consequent absorption by intestinal walls. Also, lecithin has been observed to attract free fatty acids in the bloodstream and move them away from arterial walls. More importantly, it inhibits the release of bad cholesterol and instead raises good cholesterol levels.
Induces Weight Loss
There are dietary supplements that make use of lecithin to assist weight loss. Since the amount of lecithin present in our diet contributes to the ability of the intestinal walls to break down fats, notably cholesterol, it practically flushes away unwanted calories. Lecithin is a part of a class of compounds called lipids, and, as a lipid, it is readily utilized by the cells to burn fats and power cellular functions.
Phosphatidylcholine, a major constituent of lecithin, is in the employ of every cell in the body as a form of protection and in cellular communication. It is one of the compounds that make up the lipid bilayer of cell membranes. Unfortunately, our systems use up more lecithin as a dynamic source of energy than what we supply our body, and this explains why we become more susceptible to stress.
Protects the Liver
Lecithin has always shown to be one of the compounds that promote liver health, and has been in use against certain diseases of the liver such as cirrhosis. This compound is responsible for speeding up the metabolism of lipids in the liver, and produce them only when needed, thereby removing the hazards associated with the buildup of fatty tissues that interferes with the functions of the liver.
Helps during Pregnancy
Choline is one of the most important compounds during pregnancy. It is in itself an essential nutrient with established daily value, being required to support healthy body functions, and lecithin is its best known precursor. Intake of lecithin before getting pregnant is recommendable as choline must be produced at sufficient amounts prior to conception to ensure healthy fetal development.
Lecithin, being a precursor of choline, is involved in improving brain function. There are neuronal processes that rely entirely on choline, whose absence in the nervous system results in decreased activity of these processes. In addition, it has long been postulated that the functional decline tied to aging is due to the depleting levels of choline in the body. Hence, it is prudent to replenish our choline reserves by eating foods rich in lecithin.
May 02, 2009 11:41 AM
Methionine is an essential amino acid, meaning that it is not synthesized by the body, and so has to be taken as part of your diet. It also contains sulfur, one of two sulfur-containing amino acids that can form proteins, the other being cysteine. It is a precursor for taurine, which is an aminosulphonic acid, and not strictly an amino acid, which together with cysteine supports the health of your cardiovascular system and helps to eliminate toxins from the body.
Maintenance of Cell Membranes
It is also an important intermediary in the maintenance of cell membranes. Phospholipids are fat-soluble components of the cell membrane, Phosphatidylcholine being a very important example. Also known as lecithin, this substance is derived from choline, itself biosynthesized in a chemical pathway involving S-adenosylmethionine.
This substance is made in the body from ATP (adenosine triphosphate) and methionine with the help of the enzyme methionine adensosyltransferase. Known as SAM (or SAM-e), S-adenosylmethionine employs a number of metabolic pathways in its reaction, though generally aminopropylation, transmethylation and transsulfuration. These add aminopropyl, sulfo and methyl groups to a number of substances, the most common being the methylation of proteins, nucleic acids and lipids.
Phosphatidylcholine is produced by the enzyme-catalyzed sequential methylation of Phosphatidylethanolamine, SAM donating the methyl groups. The maintenance of the integrity of the cellular membrane by Phosphatidylcholine is critical to all of the basic processes in human biology, including communication between cells, flow of information and bioenergetics.
A by-product of this reaction is homocysteine, formed in the liver from the S-adenosylhomocysteine that SAM is changed to after donating methyl groups. Excess homocysteine in the blood can create the risk of myocardial infarction and cardiovascular disease. SAM is also of use in the treatment of depression and of arthritis.
Creatine is a substance well known to athletes as being useful in provide short-term energy for high-intensity training. Although available in the diet, about 50% creatine used by the body is biosynthesized from methionine and two other amino acids, glycine and arginine. It allows a burst of energy lasting about 10 seconds, carried out without the use of glycogen reserves or fatty tissue.
Glycine and arginine combine to release ornithine as a by-product, and form guanidino acetate. SAM donates a methyl group to the latter to form creatine, about 95% of which is then stored in the skeletal muscle tissue. The stored creatine phosphate has the effect of allowing the muscle cells to hold more water, which also enables an enhanced level of protein synthesis, and hence an increase in muscle bulk, which also results from the increased blood flow resulting from the short-term high-intensity exercise that creatine allows.
Creatine can also increase the levels of MRF4 (myogenic transcription factor), resulting in an increasing in the myonuclei provided by satellite cells to damaged muscle tissue, that not only repair damaged muscle fibers, but also increase their ability to grow.
Detoxification of the Liver
Substances that help the liver to process fats, or lipids, are known as lipotropic, and the important lipotropics in human biochemistry are imositol, betaine, choline and methionine. They prevent fat from accumulating in the liver, and methionine is also useful in its effect of glutathione. This is a substance that helps the liver to neutralize toxins, such as excessive doses of acetaminophen, and its supplies are regulated by methionine.
Methionine and Autism
Research into autism is closely studying the Methionine/Glutathione Transsulfuration Pathway. This pathway is a very important biochemical means of detoxification, whereby toxins are methylated and then excreted. This pathway seems to be disrupted in autistic individuals.
Not only that, but disruption can lead to oxidative stress which results in many health problems. An example of this is the build-up of the oxidant homocysteine when there is insufficient Vitamin B6 to convert it into cysteine. This has been discussed previously, and is discussed again below.
Although research is in its infancy, it appears that AIDS sufferers also have decreased levels of methionine in their blood. It is believed that the process of AIDS could be linked to this, particularly the dementia that can occur as a result of the deterioration of the nervous system.
It is also hoped that it can help with some symptoms of Parkinson's disease, and pancreatitis. Initial research into this use of methionine has been very promising, as are studies into its use for urinary tract infections. It appears to operate like cranberry in this respect, preventing bacteria from attaching to the cell walls and multiplying in the urinary tract.
Methionine is believed to be essential for the formation of collagen, and for healthy pliable skin, hair, nails and other forms of connective tissue. For this reason it is often used as a supplement for the treatment of arthritis, although an excess should be avoided for reasons discussed above. S-Adenosylmethionine generates homocysteine during the biosynthesis of Phosphatidylcholine, and this can cause cardiovascular problems.
So stick to the recommended doses when you use methionine as a supplement. Used properly, and according to instructions, it offers many health benefits, and can also be used to bulk up your muscle tissue and give increased energy when you need it most.
Dietary sources include fish, eggs, lentils, onions, garlic, meat, seeds, spinach and yoghurt. A good supplement would be from 800mg - 1000mg per day, and is best taken along with a B vitamin complex, or at least folic acid and vitamins B6 and B12, in order to prevent the increased generation of homocysteine.
Methionine also promotes the excretion of estrogen, so is a possible supplement for women on oral contraceptives that lower the production of this hormone. The elderly might also benefit from a supplement although, if taken for any specific condition, your health professional should be consulted first, as they should be for any supplement.
Nevertheless, methionine is a very useful supplement, and can be taken to prevent a large number of conditions. Research is continuing on its effect on AIDS patients, and Parkinson's, and it is hopeful that it will one day be recommended to help people suffering from these conditions.
April 05, 2009 01:40 PM
Attention deficit hyperactivity disorder (ADHD) is the newest name that has been given to a group of disorders of the central nervous system. With the long list of names this disorder has been given over the years, it is often confusing as to which criteria are for a diagnosis of ADHD or ADD. It is estimated that between 3 and 5 percent of children in the United States have ADHD, meaning that at least one child in a classroom of twenty-five to thirty children will have ADHD. There are three times as many boys diagnosed with ADHD, but the condition is increasingly being diagnosed in girls as well.
Although ADHD was primarily thought of as a childhood disorder, it can be found in adults as well. Experts have estimated that as many as 8 million adults may be affected, but 80 percent of them do not realize it. Some studies show that there is significant decline in ADHD symptoms as a person ages, while others estimate that between 30 and 70 percent of children with ADHD will carry some symptoms into adulthood. ADHD is a more complex disorder in adults, but it manifests itself into a problem with self-regulation. Without this self-control, an adult’s ability to do tasks is impaired. This condition can lead to marital conflicts, substance abuse, and financial problems. Infidelity is common because ADHD adults easily become bored with things, including spouses.
Factors that have been linked to the development of ADHD include heredity, anxiety, allergies, smoking during pregnancy, hyperinsulinemia, oxygen deprivation at birth, environmental stress or pollutants, artificial food additives, injury, infection, lead poisoning, and prenatal trauma. More emphasis has been placed on the role of diet in ADHD in recent years. Many people with these conditions react to certain preservatives, dyes, and salicylates in foods. These problems can cause the balance of chemistry in the brain to be thrown off, which produces undesirable changes in behavior. A low-protein diet may also be a contributing factor. Although a hotly debated topic for decades, studies have definitely shown that food additives do play a major role in hyperactivity.
Many researchers feel that ADHD is being over-diagnosed nowadays. It is difficult to accurately diagnose this condition because many of the symptoms appear in the normal, healthy children at many times during childhood. In fact, more than 60 percent of parents suspect that their child has ADHD at some point in their upbringing. What may merely be creativity or a high energy level can be diagnosed as ADHD. A diagnosis of ADHD should be made by a team of specialists who are experts in the disorder and it is wise to get a second opinion.
One should considered nutritional deficiencies and dietary measures for treating ADHD. The following nutrients are recommended: calcium, magnesium, GABA, a multivitamin and mineral complex, Omega-3 fish oil, Pycnogenol, Quercetin, SAMe, acetylcholine, DMAE, l-cysteine, Phosphatidyl serine, vitamin C with bioflavonoids, and zinc. Additionally, the following herbs may be beneficial: ginkgo biloba, ginseng, mullein oil, valerian root, catnip, chamomile, gotu kola, hops, kava kava, lemon balm, licorice, lobelia, oats, passionflower, skullcap, St. John’s wort, thyme, and wood betony.
Creating a nutritionally sound diet for children and adults can go a long way to controlling ADHD and ADD in general. Reducing sugar intake and adding good quality food that hasn’t been over processed which removes the needed vitamins, minerals and phytonutrients we all need to live healthy lives. The above vitamins, minerals and herbs are suggested to be helpful for those suffering as well as those who aren’t, but always consult your health care provider before adding dietary supplements to ones diet while on prescription drugs. Quality vitamins can be found at your local or internet health food store.
*Statements contained herein have not been evaluated by the Food and Drug Administration. Vitamins, minerals, and herbs are not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.
April 01, 2009 05:35 PM
Infertility is typically defined as a failure to conceive after a year or more of regular intimate activity during the time of ovulation. This term can also refer to the inability to carry a pregnancy to term. About 6.1 million American couples are impaired when it comes to their ability to have children, with 2.1 million of these couples being infertile. The exact cause of the problem can be extremely difficult to pinpoint, as ovulation, fertilization, and the passage to the fertilized ovum through the fallopian tube and to the uterus are extremely complex processes. In order for pregnancy to occur, many events must work together perfectly.
In 40 percent of infertile couples, problems that affect the male partner are either partially or wholly the cause of infertility. Infertility in men is usually the result of a low sperm count or an anatomical abnormality. There are a variety of factors that can result in a low sperm count. Among these factors are alcohol consumption, endocrine disorders, exposure to toxins, radiation or excessive heat, recent acute illness or prolonged fever, testicular injury, and rarely, mumps-induced wasting of the testicles. An abnormal enlargement of veins that drain the testicles, referred to as varicoceles, can cause infertility in men. This is because the veins of the testes are no longer able to moderate the temperature of the testicles correctly, which can negatively affect sperm.
The most common causes of infertility in women include an ovulatory failure or defect, blocked fallopian tubes, endometriosis, and uterine fibroids. Additionally, some women are able to develop antibodies to their partners’ sperm, which causes the woman to almost be allergic to them. Chlamydia, a transmitted disease which affects 4 million Americans each year, also causes many cases of infertility. There are also psychological issues, such as stress or fear of parenthood, which can also contribute to infertility.
However, in most cases, stress is usually the result of infertility, not the cause of it. Sperm abnormalities account for about 41 percent of infertility cases. The following reasons are the most common to explain why couples cannot conceive: the woman has endometriosis; the man has abnormal sperm, a low sperm count, or erectile dysfunction; the woman’s fallopian tubes are blocked; ovulation takes place rarely or irregularly; the couple is unable to have complete intimate relations; the cervical mucous attacks and kills the sperm; the woman does not manufacture enough progesterone to carry a baby to term; the woman is over thirty-four; and/or one or both members of the couple eats a poor diet and experiences too much stress. The following nutrients are extremely beneficial in helping one or both partners deal with infertility: selenium, vitamin C with bioflavonoids, vitamin E, zinc, DMG, octacosanol, Phosphatidyl choline, essential fatty acids, l-arginine, manganese, proteolytic enzymes, pycnogenol, raw orchic glandular, raw ovarian glandular, 7-keto DHEA, vitamin A, and vitamin B complex. Also, the following herbs have been shown to be beneficial in dealing with infertility: astragalus, damiana, ginseng, sarsaparilla, saw palmetto, yohimbe, dong quai, false unicorn root, gotu kola, licorice root, wild yam root, green oat, and yin-yang-huo. It should also be noted that heavy use of Echinacea, ginkgo biloba, and St. John’s wort may cause infertility in men, and should be avoided.
Infertility can be a complicated and mentally depressing due to lack of pregnancy by both men and women. Depression can lead to more stress and needs managed by a health care provider. Always consult your doctor when you think you are infertile. Natural vitamins like the ones listed above are available at your local or internet health food store. Look for name brands vitamins to ensure you receive quality supplements.
*Statements contained herein have not been evaluated by the Food and Drug Administration. Vitamins and herbs are not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.
March 23, 2009 01:56 PM
Our memory is as natural to us as breathing. An ability we all have, but don’t often think of, it doesn’t seem to cross our mind until we perceive that we are losing the ability. Memory lapses are an annoyance in themselves, but the anxiety that often comes along with them seems to be even worse. We often wonder if our memory problems are a symptom of some other problem like midlife depression, arteriosclerosis, or even Alzheimer’s disease. Although Alzheimer’s disease is a fairly common disorder among older people, one must realize that most memory lapses have nothing to do with Alzheimer’s disease.
Generally, it is believed that increasing age brings about an increased likelihood of developing memory loss. The mildest form of this illness is called age-associated memory impairment. This is characterized by one’s perception of his or her own memory loss and it is estimated that it is experienced by 40 percent of Americans over the age of sixty-five. Not all memory loss is attributable to aging, as occasional memory lapses are a natural normal part of life at almost any age, and are not likely to precede serious memory loss. With a proper diet, nutrition, and memory use, the memory should remain sharp and active well into one’s nineties or beyond.
One big reason why people suffer from memory loss is an insufficient supply of necessary nutrients to the brain. The life of the body is in the blood, as it literally feeds and nourishes every cell within our bodies. Only certain substances are allowed to pass from the bloodstream into the brain, thanks to the protective envelope that is known as the blood-brain barrier. If the blood is thick with cholesterol and triglycerides, the amount of nutrient-rich blood that can pass through the blood-brain barrier decreases. This can result in the brain becoming malnourished over time.
The functioning of the brain also depends upon substances that are referred to as neurotransmitters, which are brain chemicals that act as electrical switches in the brain and are responsible for all the functions of the body. If the brain does not have an adequate supply of neurotransmitters, or the nutrients to make them, it starts to develop something similar to a power failure or a short circuit. If you are trying to recall as specific fact or piece of information and your mind goes blank, it is likely that the above “short circuit” has occurred.
There are many other factors that are involved in the deterioration of the memory. One of the most important is exposure to free radicals, which can cause huge amounts of damage if the memory is unchecked. Alcoholics and drug addicts often suffer a great deal of memory loss, with alcoholics being notorious for huge memory gaps that occur even though they are conscious. Allergies, candidiasis, stress, thyroid disorders, and poor circulation to the brain can also contribute to memory loss, while hypoglycemia can play a role in memory loss as well, as the brain requires that the level of glucose in the blood fall within a specific narrow range. Wide swings in blood sugar levels affect brain function and memory.
The following nutrients are beneficial in dealing with and preventing memory loss: acetylcholine, boron, DMAE, garlic, huperzine A, lecithin granules, manganese, multivitamin and mineral complex, omega-3 fatty acid complex, Phosphatidyl choline, Phosphatidyl serine, SOD, vitamin A, vitamin B complex, vitamin B3, vitamin C, vitamin E, zinc, acetyl-l-carnitine, l-glutamine, l-tyrosine, coenzyme Q10, DHEA, DMG, melatonin, NADH, pregnenolone, RNA and DNA, Brahmi, ginkgo biloba, anise, blue cohosh, ginseng, gotu kola, and rosemary.
All of the above mentioned as well as formulas tailored to help improve memory can be found in capsule, table, or power forms. Remember, only look to name brands such as Solaray, Source Naturals and Natures Plus for quality products. Memory vitamins and herbs can be found at your local or internet health food store.
*Statements contained herein have not been evaluated by the Food and Drug Administration. Vitamins and herbs are not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.
October 31, 2008 04:28 PM
Contrary to popular belief, Attention deficit and hyper activity (ADHD) doesn’t always go away when children grow up. Many of the children affected by this disorder as children carry it on into adult hood. This complicated disease can cause all sorts of problems mostly lost of work.
One survey studying over seven thousand workers between the ages of eighteen and forty four discovered that three and one half percent of these workers studied had ADHD. The ability to concentrate cost these individuals over twenty days of work. Both women and men experience mood, anxiety and most likely abuse drugs and alcohol. Fortunately there is an alternative, changing ones diet can help.
Dietary changes can help reduce the occurrence of ADHD in both children and adults. Have you ever noticed when you eat a meal high in carbohydrates you become sleepy where a meal higher in protein then carbohydrates does not make you sleepy but increase your mental acuity?
A high protein meal can reduce the amount of tryptophan that crosses the blood brain barrier in turn causes more phenylalanine and tyrosine to enter the brain. These two amino acids boost mental alertness. They are converted into neurotransmitters like norepinephrine, epinephrine, and dopamine which are adrenaline like neurotransmitters. High carbohydrate meals cause an insulin spike in the blood which causes the body to absorb protein into the muscles and frees up tryptophan.
Tryptophan when not in competition with other amino acids will cross the blood brain barrier which then is converted to serotonin a sleep neurotransmitter. To help over come this, one should eat a meal high in protein at breakfast and moderate protein / carbohydrate meal at lunch, leaving the last big meal of the day rich in carbohydrates.
Some older individuals may notice that they have a hard time sleeping at night; this may largely be due to a high protein meal later in the evening which stimulates the brain. A over stimulated brain will hinder ones sleep and could cause insomnia.
Other things that can help with ADHD are omega-3 fish oil that is high in DHA, Phosphatidyl serine, and DMEA. The later two convert to neurotransmitters that can help support healthy mental function and alertness.
June 14, 2008 03:22 PM
DMAE (dimethylaminoethanol) enhances mental function through the improvement of concentration, mental clarity and mental alertness. It is also a mild brain stimulant because it increases and sustains the energy levels in the brain. It also improves the level of restful nighttime sleep because the sleep is deeper and less time is needed to reach a rejuvenated state. DMAE helps to boost mental function through an increase in the levels of acetylcholine and choline. These are the brain’s chemical messengers.
Because of DMAE’s ability to stimulate mental cognitive function, it also has been shown to improve learning, increase intelligence and elevate mood.
* Accelerates mental processes * Decreases irritability and overactivity * Does not cause drowsiness * Improves concentration * Improves IQ * Increases attention * Relieves mild depression * Aids in long-term treatment of schizophrenia
It is believed that DMAE may also increase physical energy. Athletes and other active individuals are using DMAE more and more because of its ability to enhance these brain functions. The connection between the mind and muscles is a means to focus on form and reduce the risk of injury. So, when the mind is enhanced, it communicates better with the muscles to improve and refine function.
Due to DMAE’s mild stimulating effect on the brain, athletes report that it is a good alternative for a quick lift instead of coffee. They also believe the stimulating effects last longer than they do with caffeine. DMAE used as a mild stimulant is also safer and healthier than caffeine.
How It Works:
DMAE, once consumed, is transported to the liver where it is converted into choline through the process of metabolism. A small amount is then converted into acetylcholine, which is a brain transmitter. Through this process, DMAE increases the levels of these brain transmitters (neurotransmitters). This causes a boost in mental cognitive function and memory.
Acetylcholine is also responsible for helping to conduct nerve impulses in the brain. Choline is also converted in the brain into Phosphatidylcholine. This chemical rebuilds and protects existing cell membranes inside the brain. DMAE has the ability to cross the blood-brain barrier faster than choline. Through this quicker travel, DMAE enhances cell protection and repair and helps our brains function better and create enhanced, positive behavioral changes in most people.
Other DMAE Uses:
DMAE is being studied for use in aiding a movement disorder in Parkinson’s patients. This disorder, called dyskenesis is caused by L-Dopa, which is administered to treat the effects of the disease. DMAE seems to counteract dyskenesis effectively and safely without interfering with the benefits of the therapy. DMAE is proving to reduce the effects of other disorders that involve involuntary movements. Two of these disorders being treated are blepharospasm (eyelid twitching) and benign essential tremors.
Age spot sufferers may find hope for treatment of their condition as well. DMAE has been found to inhibit the formation of pigment caused by aging (lipofuscin) and liver spots (lentigo). It may actually flush lipofuscin from the body, causing the skin spots to disappear over a few month’s time.
DMAE is being studied for its possible ability in helping to reduce cognitive impairments related to age. Aside from increased mental cognitive function, research has shown that DMAE may also be useful in treating the following conditions.
* Alzheimer’s disease * ADD (attention deficit disorder) * Hyperactivity
The use of DMAE as a regular dietary supplement is increasing steadily. All of its benefits in aiding mental cognitive function and brain stimulation are an attractive quality for everyone. Additional research showing that DMAE is useful in treating debilitating conditions such as Parkinson’s gives us new hope. As research continues and more new uses for DMAE are discovered, its popularity will continue to grow as well.
May 28, 2008 03:25 PM
Phosphatidylserine (PS), a phospholipid, and DHA, an omega-3 fatty acid, are major components of cell membranes, particularly the membranes of nerve cells. They facilitate the electric signals that are the basis of neuron communication, supporting memory, mood, concentration, stress control and other cognitive functions. This DHA conjugate form of PS is believed to increase the delivery of this vital compound to the brain, supporting advanced brain protection and enhanced cell function.
• PhosphatidylSerine is a phospholipid essential to the brain’s structure and function. DHA is an omega-3 fatty acid, well known for supporting healthy cognitive function.
• The combination of PS and DHA is designed to function like animal phospholipids: supporting healthy cognitive function including memory, learning, comprehension, and word recall.
• With Phospatidylserine/Dha Optimized, P-S from soy is conjoined with DHA from fish oil. This replicates our natural, healthy neuron membranes.
1 capsule contains:
Suggested Use: 1 capsule three times daily with meals for the first 8 weeks, then 1 capsule daily with a meal thereafter.
Lipid content by percentage
May 13, 2008 04:54 PM
Phosphatidylcholine (PC) 68% Assists in the introduction of DHA into the or Marine Lecithin heart muscle. Protects the mitochondria from oxidative damage, decreasing the impact of auditory and visual aging.
Phosphatidylethanolamine (PE) 11% Combined with PC, helps in the building of the myelin sheath.
Phosphatidylserine (PS) 9% The most widespread of all membrane PLs, protects from ischemic attacks (stroke) or age-related dementias.
Phosphatidylinositol (PI) 5% Acts on the regulation of cellular calcium. Has shown its effectiveness on obsessive compulsive disorders, panic attacks, depression, manic depression and Alzheimer’s disease.
Sphingomyelin (Sph) 5% Its pro-apoptotic activity decreases the risks of coronary hear t disease and cancer of the bowel (colon). Decreases parietal cell toxicity of bile salts. Sphingolipids are mostly present in the myelin sheathes.
Depression and Vitamins
April 17, 2008 11:20 AM
Most men dealing with depression have stories that are very similar, waking with a heavy head even in the happiest of times. A bad day is described as one in which you can’t get out of bed and it feels as if there is a dark cloud hanging over your head. Today, as the NFL season moves towards playoffs, many athletes are living with depression related to multiple concussions. A study of over 2,500 retired NFL players concluded that three concussions triple the chance of experiencing depression. This is extremely important in a sport in which brain trauma is so often and easily dismissed.
Just like helmets cover the faces of men playing a violent game, the angry aggression that is so commonly associated with normal guy behavior may actually be a mask for depression and physical injury is not needed to suffer its effects. It has actually been discovered that depression is more common in men than anyone ever knew, as male depression has often been under-diagnosed because the standard diagnostic manual portrays the depression symptoms more commonly associated with women. About six million men will be diagnosed with depression in 2008, not counting the one million more that will go undiagnosed.
The sad weepiness that is commonly associated with depression is much more commonly found in women, while a man is more likely to be short-tempered, fatigued, and uninterested in sex, work, or hobbies. However, it is work that provides depressed men a distraction to their painful inner feelings. Men are more likely to try downing their pain in alcohol or drugs instead of getting treatment. Untreated depression explains why the male suicide rate is more than four times the rate of female suicide. Although there are hormonal differences in depression of the different genders, the common factor is stress.
Although some men are open to being told they are depressed, most only act out with more anger. An effective, but not exactly subtle approach to telling a man he may have depression is leaving and article or book around the house for him to pick up. Severe depression requires immediate attention by a trained practitioner, along with various medical interventions. Once the worst is over, it is important to try to maintain a depression-free lifestyle. This can be done by reduction stress and finding social support as well as dietary changes.
This is a difficult step for men who are used to conversations which revolve around scores and transactions, but good places to start are men’s groups at houses of worship (church) or those groups such as AA if substance abuse is part of the problem. By fortifying the brain with depression-fighting nutrients, including a B vitamin complex, one can maintain and promote normal mental functioning. Many depressed people are extremely deficient in folic acid as well as dietary essential fatty acids.
Omega-3 fatty acids are needed to build healthy brain cells, along with Phosphatidyl serine. Other herbs, including eleuthero, rhodiola, and ginseng, can help the body to adapt to stress, while St. John’s wort and SAMe work as natural antidepressants.
The most severe mistake that can be made is to play down depression, which applies to raging men just as much as it does to weeping women. Both genders need to seek help if feeling this way. If you feel you are experiencing depression, seek professional help as well as look into dietary changes, exercise, and the support of family can be a good start to a healthier outlook on life.
Leci-PS - Boost Brain Power
April 10, 2008 06:03 PM
Phosphatidyl serine (PS) is an important phospholipid that is present in every biological human membrane, and therefore vital in the support of all the body’s major systems. While it plays an important role throughout the body, it is of considerable importance to the human brain. PS is actively involved in billions of neurotransmissions taking place every second within the body. its unique size and structure allows it to cross the blood-brain barrier to transfer supporting nutrients and remove waste. The brain, like every other organ, needs nutrients to function properly. PS makes it possible for these nutrients to reach their destination, by improving the quality of transmission, clearing the paths upon which they travel, and protecting brain cells from free radical corruption. Unfortunately, as the body ages, its natural production of PS steadily declines.
Phosphatidyl serine’s cognitive health benefits have also been recognized by the FDA, as evidenced by a qualified health claim stating that, “consumption of Phosphatidyl serine may reduce the risk of dementia in the elderly. Very limited and preliminary scientific research suggests that Phosphatidyl serine may reduce the risk of dementia in the elderly.”*
Considering the vast importance of this important biological multi-tasking phospholipid, NOW is devout in using only the finest Phosphatidyl serine raw materials when formulating their products. Leci-PS®, a product of Cargill Incorporated, has established itself as the absolute highest grade available. Leci-PS® contains 90% Phosphatidyl serine thus offering the highest concentration PS available anywhere within the natural product industry. It has been named GRAS (Generally recognized as safe) by the US Food And Drug Administration, and is manufactured in Cargill’s state-of-the-art GMP-Certified facility.
Natural Supplements Like Fish Oils And Phosphatidylserine Can Boost Memory
January 14, 2008 03:24 PM
We often think of our brain as being different from other organs, but the brain undergoes changes over time, just like the heart. Up until recently, brain aging and everything that goes along with it was associated with neuron failure. Actually, brain neurons do not undergo massive die-off with age. Although some neurons are lost, the brain continues to grow new ones, though at a slower pace. Decreasing cognitive function is now believed to start as early as one's late thirties, which is the result of a lowered vascular function for oxygen and nutrient supply, increased oxidative stress, and decreased production of neurotransmitters. Other issues impact memory too such as normal aging, emotional trauma, alcoholism, depression, seizures, dementias, stroke, neurodegenerative illnesses, and obesity. All of these can lead to devastating changes in mood and memory. Additionally, it is widely known that the use of cholesterol-lowering drugs can severely impact skills that involve brain functions.
Neptune Krill Oil - EPA and DHA Rich!
July 02, 2007 12:43 PM
Complete List of Now Vitamins Starting at 40% OFF.The oil of Atlantic Krill, a zooplankton crustacean, contains one of the most unique nutrient profiles ever discovered. In addition to rich concentrations of EPA and DHA, krill also boasts an impressive amount of phospholipids, all-trans retinol vitamin A, natural vitamin E, and omega-9 fatty acids. The oil is an excellent source of esterified astaxanthin—a powerful, immune supporting carotenoid that has been clinically proven to quench singlet oxygen radicals within cell membranes. The potent arrangement of naturally occurring compounds exhibits strong synergist properties that support and protect many of the body’s most vital system.*
At the most basic level, krill oil contains compounds that the body needs in order to construct healthy cell membranes. By nature, omega-3 essential fatty acids can be particularly sensitive to oxidation. Atlantic krill, however, contain antioxidants and Carotenoids that bind to these fatty acids, thus improving the biological stability. Accordingly, studies have shown that as much as 95% - 95% of the EPA and DHA in krill oil is capable of being absorbed for use throughout the body.
Among its most impressive qualities, Neptune Krill Oil contains phospholipids that are rich in EPA and DHA, and structurally similar to those produced by the human brain. The most significant include Phosphatidyl Choline, Phosphatidyl Inositol, and Phosphatidyl ethanolamine. Researchers believe that their unique structure and ability to cross the blood-brain barrier make it possible for those compounds to support brain and cognitive health.* Now Vitamins Neptune Krill Oil is manufactured under the strict quality control, and tested to be free of potentially harmful levels of mercury and other heavy metals, PCB’s, dioxins and other contaminants.
100% Pure Neptune Krill Oil
Complete Liver Cleanse
April 19, 2007 04:17 PM
Complete Liver Cleanse
Technical Data Sheet
The liver performs over 500 functions, including metabolizing carbohydrates and proteins, synthesizing and storing vitamins, and regulating hormones – naming just a few. To do this job, the liver is also required to be exposed to potentially harmful toxins and chemicals, every day.
One way to support the liver is through periodic supplementation with the proper balance of herbal ingredients, phytosterols, and fiber. Complete Liver Cleanse is a convenient, multi-ingredient formula that supports overall liver health and detoxification.
Complete Liver Cleanse:
Includes ingredients for various aspects of liver and gallbladder support:
-Herbal ingredients that support liver and gallbladder health
-Detoxifying ingredients that keep bound toxins from being reabsorbed
-Phytosterols to block cholesterol absorption in the intestines
-Fiber that moves cholesterol and toxins out of the body
-Oat beta-glucan fiber with up to 4 times higher viscosity than other beta-glucan
-Simple, two week liver cleanse program
Each 3 capsules contain:
Calcium (as calcium D-glucarate) 13 mg
Proprietary PuraFiber Blend: 1 mg
Viscofiber Oat B-Gucan Concentrate, phytosterols
(beta sitosterol, campesterol, stigmasterol, brassicasterol,
and other plant sterols), and glucomannan
Milk Thistle (Silybum marianum) Fruit Phytosome 220 mg
One part Milk Thistle Extract, standardized to contain 80%
Silymarin bound to two parts Phosphatidylcholine (soy) using
a patented process
Burdock (Arctium lappa) Root Extract 4:1 100 mg
Calcium D-Glucarate 100 mg
Boldo (Peumus boldus) Leaf Extract 2:1 75 mg
Turmeric (Curcuma longa) Rhizome Extract 50 mg
Standardized to contain 90% curcuminoids
Dandelion (Taraxacum offinale) Root Extract 4:1 50 mg
Artichoke (Cynara scolymus) Leaf Extract 30 mg
Standardized to contain 13-18% caffeylquinic
Acids calculated as chlorogenic acid
Contains no: sugar, salt, yeast, wheat, dairy products, artificial coloring, artificial flavoring, ingredients of animal origin, or preservatives. This product contains natural ingredients; color variations are normal.
Other ingredients: See label for most current information
Viscofiber is a registered trademark of Cebena Bioproducts, Inc. The use and composition of the Viscofiber proprietary formula is protected by patients and patent applications filed in the
This product contains calcium D-glucarate, the use of which is licensed from Applied Food Sciences, LLC, and protected by
HOW DOES IT WORK?
Every day, the liver must process an almost unbelievable amount of blood – at a rate of three pints every minute. All the while, the liver performs over 500 physiologic functions, including protein and glucose synthesis, carbohydrate metabolism, vitamin and mineral storage, synthesis of clotting factors, urea formation, metabolism of medications, and the production of bile. The liver also assists in hormonal regulation, blood glucose control, and other regulatory functions.
Harmful substances that have been neutralized by the liver are carried to the intestines and kidneys for excretion. They are transported by bile, a greenish, watery solution that is synthesized, and continuously being excreted, by the liver. Stored in the gallbladder, a small sac cupped in the under surface of the liver, bile is also required for the digestion of dietary fats. However, in the case of toxins, bile is primarily an early transporter of the toxic compounds to the intestines, where they can be bound to fiber that helps transport them out of the body. Environmental toxins, including lipid (fat) soluble toxins, are broken into water-soluble components by bile to be excreted through the kidneys or colon.
Detoxification refers to the process of excreting potentially harmful compounds that are both generated by the body and acquired through exposure to the environment. In the body, toxins are generated as by-products of cellular metabolic processes. Examples include dead and digested bacteria, hydrogen peroxide, cellular debris, and carbon dioxide.
The Environmental Protection Agency has determined that the amount of environmental toxins in the air, groundwater, and soil has increased significantly in the last 40 years. In fact, the use of pesticides has doubled every ten years since 1945. Americans are increasingly exposed to heavy metals, pesticides, fossil fuel emissions, sulfur oxides, hydrocarbons, and other harmful chemicals. The Environmental Protection Agency reports that traces of toxic chemicals can now be found in nearly every American.
Herbal Liver Support
One of the major components in Complete Liver Cleanse is its milk thistle extract, standardized to contain 80% silymarin, the plant’s most bioactive compound. Milk Thistle provides support, at a cellular level, for healthy liver function. A patented delivery system, known as the Phytosome process, provides superior absorption of the milk thistle extract.
Silymarin, a key compound found in milk thistle, is a mixture of flavonoids with a long history of liver support. Silymarin supports the health of Kupffer cells, specialized liver cells responsible for removing bacteria, old blood cells, and other foreign matter from the liver’s blood supply. Silymarin scavenges free radicals (superoxide anion radical and nitric oxide) produced by activated Kupffer cells, supports healthy leukotriene levels, and supports glutathione production that is used in detoxification.
Silymarin also supports the health of hepatocytes, highly versatile liver cells with unique physiologic functions. Studies of silymarin have demonstrated that it supports the health of the hepatocyte outer membrane, which is crucial to the liver’s detoxification processes. Silymarin also supports the healthy regenerative ability of the liver through support of protein synthesis in the hepatocytes.
A special, patented proves known as Phytosome enhances the absorption of milk thistle in Complete Liver Cleanse. The Phytosome process pairs herbal ingredients with Phosphatidylcholine molecules. Phosphatidylcholine is a naturally occurring substance found in soybeans, egg yolks, and some vegetables. In the body, Phosphatidylcholine is an important building block of cell membranes.
When milk thistle (or other herbs) are bound with Phosphatidylcholine, the Phosphatidylcholine molecule facilitates absorption through the intestines into the bloodstream. Research has shown increased blood and serum levels for phytosome herbs in comparison to the individual herb alone.
To test whether binding an herb with Phosphatidylcholine increased its bioavailability, researchers gave volunteers identical amounts of either milk thistle alone, or milk thistle phytosome. The researchers then took blood sample from the participants and measured the level of silybin (a key compound in milk thistle). The measurements showed that silybin levels in participants taking the phytosome form of milk thistle were higher, and that silybin was detected for a longer time, than those who took milk thistle without the phytosome delivery system.
Other Herbal Liver Supportive Ingredients
Herbal extracts are often at their best when they are working synergistically – that is, when different constituents of each plant work together and support each other. Complete Liver Cleanse contains a variety of herbal extracts that have noted benefits for supporting the body’s healthy bile flow and free-radical scavenging effects. These ingredients provide a wide spectrum of liver supportive benefits.
For instance, dandelion root extract supports healthy bile flow from the gallbladder.
Burdock is originally native to Europe and Asia, but was introduced to
Burdock root (Arctium lappa) supports the natural physiologic processes of organs involved in detoxification and elimination: notably, the liver, kidneys, and intestines.
Bolodo (pemus boldus) is a small evergreen native to South America, but naturalized to southern
In scientific studies, boldo appears to have strong free-radical scavenging ability, mostly attributed to the catechin and flavonoids content of its leaves. In a clinical study, boldo also appears to relax smooth muscle and support intestinal transit time.
Artichoke Leaf extract specifically supports healthy bile production in the liver and healthy gastrointestinal function in general. Research into artichoke’s gastrointestinal supportive properties has included at least three clinical trials. Artichoke’s role in supporting healthy cholesterol levels within normal limits has also been investigated.
Turmeric (Curcuma longa) is a perennial shrub native to southern
More recently, turmeric has been investigated for its support of healthy bile secretion, and pancreatic and gastric function.
In a scientific study, dietary curcuminoids derived from turmeric supported healthy lipid metabolism and cholesterol levels already within normal limits.
Curcumin has also been shown in scientific studies to enhance the activity of glutathione S-transferase - an enzyme responsible for linking glutathione (one of the body’s natural antioxidants) with toxins to help remove them from the body. In this way, it provides additional support for healthy liver function.
The process of detoxification is the breakdown and excretion of substances that are no longer needed or may be harmful to the body. One of the ways in which the body excretes hormones and toxins is by binding them to glucuronic acid in the liver, and then excreting this compound in the bile.
However, this process can be disrupted by B-glucuronidase, an enzyme that is produced by intestinal bacteria. This enzyme has the ability to break (uncouple) the chemical bond established by glucuronic acid. This action releases the bound toxins, which are then reabsorbed into the body instead of being excreted.
Calcium D-Glucarate is the calcium salt of d-glucaric acid. It is found in both the human body, and in some plant sources, including broccoli and oranges.
Calcium d0glucarate enhances the body’s detoxification systems by inhibiting the actions of beta-glucuronidase. This helps decrease the portion of active compounds that could be hazardous to the body.
Cholesterol is a waxy, fat-like substance that is vital to fat digestion, cell structure, nerve insulation and hormone production. Cholesterol comes from two sources: dietary or “exogenous” cholesterol absorbed in the intestine, and “endogenous” cholesterol formed mostly by the liver and stored in the gallbladder.
Cholesterol occurs in two forms known as lipoproteins. Lipoproteins act as transports that carry fat s to and from the cells.
High-density lipoprotein (HDL) carries low lipid density cholesterol (LDL) away from arterial walls and returns it to the bloodstream. LDL then travels back to the liver, which processes and eliminates it. While high levels of HDL cholesterol is desirable, high amounts of LDL cholesterol is not supportive of optimal health.
LDL-cholesterol is both synthesized in the body, or absorbed into the bloodstream through receptor sites in the intestines. Think of these receptors as “parking spaces” for cholesterol. As it happens, the liver can receive up to 500 mg per day of cholesterol from intestinal absorption. (It can also produce as much as 1000 mg per day).
One way to help reduce the absorption of LDL cholesterol molecules it to occupy their “parking places” in the intestines. Phytosterols in Liver Cleanse are essentially the “fat” of plants. They’re found in nuts, corn and rice and are some of the “good” fats associated with the benefits of olive oil, flaxseed oil and other healthy oils.
The structure of phytosterols is so similar to cholesterol that they fit perfectly in the specially-shaped intestinal parking spaces that LDL-cholesterol would normally occupy.
Taken with, or just before meals, phytosterols block the cholesterol receptor sites so that cholesterol is excreted from the body rather than absorbed. Phytosterols also have the additional role of helping promote healthy bile salt excretion in the intestines.
The phytosterol blend in Complete Liver Cleanse can help minimize the absorption of cholesterol from high-protein food sources, help retain healthy cholesterol levels that are within normal limits, and move bile sat through the digestive system.
Fiber and detoxification
Fiber plays a key role in the removal and excretion of intestinal toxins in detoxification. Only fibers that can effectively bind toxins will be successful in eliminating these harmful substances. Due to the unique benefits of individual fibers, the best binding, removal, and elimination effects are noted when combining different fiber types. Complete Liver Cleanse contains a combination of oat beta-glucan and konjac fiber that has been shown in scientific studies to bind to bile salts.
Dietary fibers are complex mixtures of cellulose, hemicellulose, pectin, mucilage, and gums, which are resistant to digestive fluids or enzymes – that is, they aren’t absorbed into the bloodstream. So, while fiber itself doesn’t necessarily provide nutrients, it does promote laxation and modulate gastric and intestinal physiology. Intestinal flora that normally reside within the colon utilize fiber as a medium for microbial fermentation, resulting in the synthesis of the vitamins, vitamin K and biotin, and the formation of short chain fatty acids, or SCFA.
SCFA have a simple, but important job: to be absorbed by the colon mucosa, increasing fecal matter bulk and providing energy. Fiber has been demonstrated in numerous clinical studies to provide support of gastrointestinal, cardiovascular, immune, and endocrine function health.
Complete Liver Cleanse also features two unique fibers to promote detoxification – konjac and oat beta-glucan.
Konjac, (Amorphophallus Konjac) is a tuber native to
As a fiber, konjac has shown positive results maintaining healthy cholesterol levels within normal limits in clinical studies. This beneficial effect is due to konjac’s ability to boost excretion of bile acid.
Oat beta-glucan has been a widely studied fiber source for supporting healthy cholesterol levels within normal limits.
In a randomized clinical study, oat beta-glucan showed support of healthy HDL/LDL ratios already within normal limits in individuals over a three week trial.
Closely linked to cholesterol, oat beta-glucan has also been studied for its support of healthy bile excretion.
Fiber has benefits beyond maintaining healthy cholesterol levels already within normal limits. It also contributes to healthy blood sugar levels already within normal limits. In a double-blind, clinical study, the oat beta-glucan fiber used in Liver Cleanse was shown to have 4 times higher viscosity than another high concentrate beta-glucan fiber.
Viscosity – the resistance to flow – is an important factor in beta-glucan, and all fiber. Water, for instance, would have a low viscosity, because it provides very little resistance to movement. Fiber, on the other hand, should have a higher viscosity in order to maximize its transit time through the GI tract, providing a gentle “scrubbing” on the intestinal walls. Therefore, the higher the viscosity, the greater the potential benefit.
Three capsules in the morning and three capsules at bedtime for 14 days.
Warnings: Do not use if you know or suspect you have an obstructed bile duct or problematic gallstones. If pregnant, nursing or taking prescription drugs, consult your healthcare practitioner prior to use. Keep out of reach of children.
Which Calcium is Best?
October 17, 2006 03:52 PM
Customers walking into a health food store today are faced with a vast array of calcium supplements. They might ask: which one should I pick? Which one is best? Not easy questions to answer. All calcium forms will accomplish the same task: providing your body with a nutrient that it needs to build healthy bones and teeth; however, which form of calcium has the features that you want in a calcium supplement? Looking at shelves of calcium products is kind of like shopping for a car; there are many makes and many models—some are basic and others are more sophisticated.
Fortunately, there are many forms of calcium to satisfy your needs. Like the car lot, a health food store offers many options; therefore, you have to select a calcium product that consumers will feel confident in taking regularly and that will provide the most benefit.
Some consumers have done research and will come armed with information. They have already made choices based on advertising, word-of-mouth or an article they have read. They already know the form of calcium they want, be it a “Ferrari” or a “Ford.” If the client doesn’t have a specific preference: asking these basic questions will help in the selection process:
1. Do you prefer tablets, capsules, softgels, liquid or powder?
2. Do you have high or low stomach acid?
3. Do you have absorption issues?
What is calcium?
Calcium (Ca) is one of the most important minerals found in our bones and teeth—99 percent of body calcium is found there. But the calcium molecule does not like to travel alone and, in its more basic state, it comes bounded to carbon (C), Oxygen (O), and/or hydrogen (H) molecules or in more complex form, it is bonded to organic or amino acids that act as stabilizing carriers. On most labels, the amount of calcium listed actually indicates the pure or elemental calcium because it is that amount of the calcium that is deemed important to our daily supplementation, not the complex of the materials with which it is bonded.
Where does calcium come from?
Other than the calcium found in bone, the only natural form of calcium found in nature is calcium carbonate, a calcium molecule bonded to one molecule of carbon and three molecules of oxygen (CaCO3). One of the most common minerals on the face of the earth, calcium carbonate is called calcite, aragonite or vaterite by geologists. In its geological form, it constitutes approximately four percent, by weight, or the earth’s crust.
Commercial sources of calcium carbonate used to make supplements are: limestone, dolomite, oyster cell, egg shell, coral and sea water (have you ever seen that white deposit left by hard water? That’s mostly calcium carbonate). Calcium carbonate is the starting material for all other forms of calcium supplements. From this starting material, calcium can be reduced to more concentrated forms, such as oxide or hydroxide or it can be chelated (bonded) to organic acids and amino acids to help support enhanced absorption.
Lets look more closely at the different forms of calcium that are available as supplements.
Calcium Oxide (CaO): this form is 71 percent elemental calcium and is also called “lime” commercially. This is one of the oldest and most inexpensive forms of calcium used in a variety of commercial applications and it is occasionally used in supplements where space and price are a factor. It sometimes can be found in inexpensive mass market calcium/mineral combinations or multivitamin/mineral products and in a unique algal calcium from Japan. Unfortunately, CaO is a strong alkali that may cause stomach distress, which is why it isn’t often used in health food supplements.
Calcium Hydroxide (CaHO): at 54 percent elemental calcium, it is the next highest source of elemental calcium and is also known commercially as “slaked lime.” It is used where space is an issue. Although it is also a strong alkali, it is more stable than calcium oxide. It is most often used as a component of multi-mineral formulations or in addition to other forms of calcium (i.e., calcium citrate) to provide potency where space is an issue. It is not often used as a single ingredient in health food supplementation. This is for people who want a high dosage of calcium from a minimum amount of pills in multi-mineral formulas.
Calcium Carbonate (CaCO3): at 40 percent elemental calcium, it is the most widely used form of calcium in single ingredient calcium supplements as well as combination supplements. Inexpensive and an abundant source of elemental calcium, it is the only form of calcium found in nature outside of bone. It is the primary form of calcium used in the mass market and in antacid products. This is for people who have high stomach acid and who need a buffering type of calcium. Also for people who want a high dose of calcium in a minimum amount of pills.
Calcium Citrate: at 21 percent elemental calcium, it is one of the most popular forms of calcium supplements in the health food market as well as the mass market. This calcium salt does not lower stomach acid as much as calcium carbonate. This calcium salt is usually recommended for people who have low stomach acid, have had stomach surgery or who need a form of calcium that will not lower their stomach acid further.
Calcium Gluconate and Lactate: these two forms of calcium are high soluble. Since the amount of elemental calcium is much lower (9 percent and 13 percent respectively), they are used more often in powder form and mixed with liquids or food. When mixed in a beverage, the calcium is already dissolved and is ready to be absorbed. This is the best calcium salt for people who have overactive bowels, who have trouble swallowing pills or who don’t like the taste of pre-formed liquid calcium supplements. These calcium powders can be mixed in juices or smoothies or added to food as they are virtually tasteless.
Calcium Orotate and Asporotate: In the mid 20th century, Dr. Hans Nieper, a German scientist, advanced a theory that orotic and aspartic salt forms of calcium are transported directly to cell membranes for better absorption. The Solaray brand developed an asporotate formula, which combines three organic acids: aspartic acid (-Asp), orotic acid (-oro) and citric acid (-tate) into one product. The asporotate formula has become one of the most popular calcium formulas and is exclusive to the Solaray brand. This product is for customers who appreciate the idea of combining the enhanced absorbability of three organic acids into one. Aspartate and citrate are also part of the krebs (energy) cycle and are natural to the body’s metabolic systems and, according to Neiper, calcium Orotate and Aspartate are mineral transporters that enter into the cells to facilitate enzymatic actions rather than being extra-cellular. For people who believe that intracellular calcium is of importance, calcium Orotate and asporotate may be good choice.
Calcium Hydroxyapatite: this is another “natural form of calcium usually as a mineral ash form bovine source bone. Bone meal is also a form of calcium from bovine bone. These forms of animal derived calcium are for customers who want a source that is closest to their own bone matrix. Not for vegetarians.
Calcium Amino Acid Chelates (*HVP): this form is calcium carbonate bonded (Chelated) to a form of amino acid complex such as whole rice concentrate or other grain source. This form is for customers who want the additional bioavailability of amino acids.
Calcium AEP: Another form of calcium endorsed by Dr. Hans Nieper who theorized that calcium would cross the cell membranes more readily when it was combined with Phosphatidyl ethanolamine or Amino Ethanol Phosphate (AEP), a nutrient found in nerve sheaths. This highly specialized form is for very educated customers who are proponets of Hans Niepers theory.
So, which form is best?
Calcium, like cars, comes in a variety of forms. Isn’t it wonderful that we have so many choices? The point is, there is no best one, there are only individual choices. Although we have our favorites, taking a calcium supplement, regardless of which one it is, should:
Our primary concern when choosing a calcium supplement should be to provide our body with the right amount of calcium daily so that our skeleton and teeth can maintain proper mineralization and strength as the cells continuously break down and rebuild. The type of calcium complex we prefer is entirely up to us.
*HVP = Hydrolyzed Vegetable Protein
An Interview with Congressman Sam Farr, Representing California’s Central Coast.
May 30, 2006 02:36 PM
Ambassador to Health Profile
An Interview with Congressman Sam Farr, Representing California’s Central Coast.
Congressman Sam Farr, a fifth-generation Californian, represents the state’s beautiful central coast. His district encompasses the length of the big Sur coastline in Monterey County, the Monterey Bay National Marine Sanctuary, the Salinas Valley “Salad bowl,” the redwoods, mountains and beaches of Santa Cruz County, and the majestic rural landscape of San Benito County. The health and wealth of this region has been strengthened by Rep. Farr’s focus on the environment, education and the economy. Rep. Farr was raised in Carmel, California and graduated from Willamette University with a BS in biology. He later attended the Monterey Institute of International Studies and the University of Santa Clara. He is fluent in Spanish. As a tough advocate for the health food industry, he has lobbied for strict federal organic standards.
Todd: Congressman Farr, thank you for taking the time to speak with us! Id also like to thank you for all the great things you’ve done for our community, form funding marine sanctuaries and authoring the Ocean’s Act to expanding Pinnacles national Monument. The League of Conservation Voters and others have recognized you as an “Environmental Hero”. And, you’ve worked hard to support the economic vitality of central coast’s $3 billion agriculture industry which includes a substantial organic segment. Our backyard here is also the home of a robust group of nutritional supplement manufacturers. An estimated 187 million Americans are currently taking dietary supplements as part of their daily healthy diet. In California, we’ve got 792 natural product manufacturers and distributors. Where do you stand on the state of our industry?
Congressman Farr: Well, thank you for the introduction and for asking to talk to me about nutritional supplement issues. I am very supportive of this industry and include myself in the 187 million Americans taking dietary supplements. I think supplements offer many safe and viable tools to maintain your health. The continued growth of this industry is an indication of both consumer confidence in the products and the products’ ability to fill the gaps where conventional medical care falls short.
Todd: It is estimated that by 2030, more than 70 million Americans will be over the age of 65 and the cost of health care could reach $16 Trillion per year. A recent study by the Lewin Group showed that by taking certain dietary supplements, seniors can lead healthier, more productive, independent lives while saving billions in reduced hospitalizations and physician services. Do you share our view that a Wellness Revolution is needed to counter the dilemma of an aging population versus shrinking health care support in the future?
Congressman Farr: Our health care system is definitely facing a challenge, especially as the Baby Boomers hit their 60’s and Americans are living longer than ever before. As a Baby Boomer myself, I am well aware of America’s aging population and the impact that will likely have not only on our social institutions but also our fiscal well-being. I agree that dietary supplements do play and will play an even larger role in the future as more seniors look for a way to augment their diets in order to stay healthy and active longer than past generations.
Todd: Our industry is regulated by DSHEA (the Dietary Supplement Health and Education Act), which was passed unanimously by Congress in 1994 to create a reasonable regulatory framework for access to, information about, dietary supplements. But many say that the FDA and DSHEA weren’t adequately funded to do the job as tasked. “Supplements are unregulated” is a false argument we sometimes hear. To ensure that the FDA is able to carry out the law as Congress intended, Representatives Dan Burton (R-Ind.) and Frank Pallone (D-N.J.) introduced H.R. 2485, the DSHEA Full Implementation and Enforcement Act of 2005. Did you support this bill and where does it stand today?
Congressman Farr: I think the DSHEA is a critical law and was proud to support it when Congress considered it in 1993 and 1994. I would certainly support H.R. 2485 if it came up for a vote in Congress. Unfortunately this bill has not moved since it was first introduced and referred to the Subcommittee on health in the house energy and commerce committee. Since this is an election year we have a tight schedule with only about 60 legislative days scheduled before we adjourn. That means it’s likely Congress will only finalize bills such as the appropriation bills that fund government before adjournment.
Todd: Our business climate has included some valid and rigorous challenges to improve our industry, from good manufacturing practices (GMP), to allergy labeling, to implications of Prop-65 in California. It’s disconcerting that a new bill, H.R. 3156 The Dietary Supplement Access and Awareness Act would try to capitalize on misconceptions about the industry. In an era of declining health care and declining insurance coverage, this bill would regulate supplements as prescription drugs. Among other things, it would also require adverse event reports to be turned over to the FDA, even though other foods, including those with identical ingredients, do not have the same requirements. This has the potential to be the next Prop-65-like Lawsuit mill. The result of H.R. 3156 would be chilling. It will knock smaller producers out of the market. It will result in higher prices for all supplements. It will decrease the availability of health-giving supplements to the public. What’s your feeling on this?
Congressman Farr: I am similarly concerned about H.R. 3156 and would oppose it if it came up for a vote in Congress. Like H.R. 2485, this legislation has been referred to a subcommittee on Health in the House Energy and Commerce Committee without any further action. The supplement industry has worked in good faith with the FDA since passage of DSHEA and H.R. 3156 would re-invent a wheel that isn’t needed. Instead, adequate funding as proposed in H.R. 2485 would provide ample oversight for the industry.
Todd: According to a recent study, 72% of the general population believe the government should fund more research on health benefits of nutritional supplements. Do you agreen and what can be done to meet this need?
Congressman Farr: I definitely agree that the federal government should play a bigger role in support of research regarding the health benefits of nutritional supplements. As a member of the House Appropriation Committee, I sit on the subcommittee that has jurisdiction over the FDA’s budget and I know the tight fiscal restraints the agency is under. I’ve worked with my colleagues to provide adequate funding, but it’s an uphill battle especially when we’re in a “robbing Peter to pay Paul” kind of situation. I recommend that people within the industry organize and use your consumer base to actively lobby Congress for additional funds. I’m fond of reminding people that the squeaky wheel gets grease – so let every Congress member and Senator know how much this issue matters to you.
Todd: When there is overwhelming scientific evidence that nutritional supplements provides relief for a disease condition, it currently takes a lawsuit to get the FDA to relent and allow the claim. Even then, the FDA strictly limits the claim and requires a disclaimer that does more harm than good in communicating this important information to the public. There is a new bill, H.R. 4282, The Health Freedom Protection Act that would end FDA and FTC censorship of health information. As an example, the 50% of all adult males who suffer from an enlarged prostate could receive relief from that condition by consuming a simple and safe ingredient, saw palmetto derived from the fruit of the dwarf American palm tree. The FDA censors that information. The public deserves a better opportunity to be informed about omega-3 EFA and heart disease, folic acid and birth defects, Phosphatidylserine and cognitive impairment. Do you agree and do you support this bill?
Congressman Farr: I agree the public needs to access to the best information possible so they can make well informed choices about their health. I likely would support H.R. 4282 if it came up for a vote in Congress. Unfortunately this bill is in a similar situation as other we’ve mentioned in this interview – and again because of the tight schedule of an election year, it’s unlikely action will happen this year.
Todd: According to the barometer study, 85% of the US population is currently using some type of dietary supplement. Do you? Looking at your busy schedule from co-chairing the House Oceans Caucus to your seat on the Travel and Tourism Caucus, you are one busy congressman! Are you popping nutritional supplements please tell us!
Congressman Farr: I do take some nutritional supplements, though they vary and since Ginkgo Biloba isn’t among them I cant remember their names off-hand! One product I do use faithfully is Airborne to help me combat germs and colds that I might get from sitting on an airplane. But, like many Americans my life is over-scheduled and combined with the amount of air-travel I do, I find nutritional supplements helpful as I try to stay healthy despite my hectic lifestyle.
Todd: Thank you Congressman Farr! Live long and prosper!
DSEA Release of Health/Cost Impact Study Conducted by the Lewin Group, Initial Results, Wash DC; Nov. 2, 2005
NNFA database. Adam.F on 3-15-06.
DSEA Nutritional Supplement Barometer Study, 2005 Report, Prepared by the Natural Marketing Institute (NMI).
Todd Williams; Source Naturals Marketing Programs Manager.
Phosphatidyl Serine - HEALTHY COGNITION BRAIN FUNCTION
December 21, 2005 11:04 AM
“To the dull mind, nature is leaden. To the illumined mind, the whole world burns and sparkles with light.” Ralph Waldo Emerson
From the moment we rise to the moment we rest, our brain is in a decision-making frenzy. When we’re thirsty, our brain tells us that we need water. When we’re hungry, it reminds us that we have a refrigerator full of food. When we’re tired, it lets us know that we need to sleep, and so on. But despite the thousands of decisions we make everyday, our brain still hasn’t figured out a way to let us know what it needs to func¬tion.
Though ironic, this raises a very serious issue. The human brain, like every other organ in the body, demands nutrition - period. Unfortunately, it leaves that up to us to figure out. Thanks to notable advance¬ments in research, we’re finally learning which nutri¬ents are most important for optimal brain function. Phosphatidyl Serine (PS) is a perfect example. This naturally occurring phospholipid has been the subject of numerous studies regarding its ability to boost cognitive function and delay (or potentially reverse) memory deterioration, and suggests that PS may be able to increase the effectiveness of neural transmissions. Interestingly, PS accounts for roughly 15% of the brain’s phospholipid supply. This is enor¬mous because phospholipids play a significant role in the billions of neurotransmissions that take place every second. Yes, billions.
Brain cells are constantly communicating with one another, and send astonishing amounts of impulses throughout the nervous system. This is accomplished via neurotransmitters - chemical messengers that send and receive impulses over the synapses of the brain and throughout the body. Mentally, we’re function¬ing at our best when these cells are well nourished. We can think more clearly, recall memories with ease and operate with greater efficiency. However, a de¬ficiency in neural-nutrients can prevent these mind messengers from functioning as they should. For¬tunately, PS has the ability to cross the blood-brain barrier to deliver critical nutrients and remove mind-slowing waste.
Consider this. The brain functions in the same man¬ner that a major airport does around the holidays. There are millions of actions taking place. Impulses departing, nutrients arriving, endless communication, the occasional problem and more reactions than any¬one could possibly count. There’s confusion, delay and emotion, not to mention the endless series of transmissions that take place every second. Imagine PS as that ultra-motivated employee who shows up to work everyday anxious to expedite everything in sight. It helps neural travelers get to and from their respec¬tive gates, ensures that they have everything they need, simplifies processes that could result in breakdown, and clears isles that are cluttered with junk. Simply stated, PS is the brain’s overachieving go-getter.
PS can help us think more clearly.
It’s 3:06 in the afternoon and you’re scrambling to get to a meeting that you’re already late for. That fluster could be the result of poor neurotransmission caused by a deficiency in essential nutrients like PS. Moreover, these innocent brain-bursts can exhaust our PS reserves, leaving us somewhere hovering be¬tween frantic and sluggish. Every impulse, thought, action, reaction, movement, emotion and desire is the end result of neurotransmitters in action. PS is a major supporter of these actions. Therefore, as we increase the amount of PS in our system, we gain the ability to think and act with greater ease.
PS can reduce the adverse impacts of stress on our body and mind.
What do we do when we’re down in the dumps? While plopping down on the sofa with a snack might be an easy solution, it comes with a price. Not only does stress interfere with mood, but it can also inspire inactivity, over-eating and sluggishness. This is due largely in part to cortisol - a catabolic hormone released by the adrenal glands in response to emotional stress. Studies done to determine the effectiveness of PS on cortisol suppression have shown that it works by suppressing the hormones that produce cortisol. As a result, supplementing with PS may be able to help reduce the amount of stress related hormones that ultimately leave us singing the blues.
PS can expedite post workout recovery time.
Endurance athletes who carefully monitor their body’s response levels are increasingly turning to PS. Immediately following strenuous activity, the body responds by releasing adrenocorticotropin (ACTH) – a hormone that discourages testosterone and encourages cortisol. By limiting ACTH pro¬duction, PS reduces the amount of muscle tissue breakdown that occurs during exercise. A common misconception is that muscles grow during exercise - wrong. In fact, muscles are torn down during ex¬ercise and grow in-between workouts – hence the term recovery. During recovery, PS helps prevent the activity of growth-inhibiting hormones. This helps athletes recover faster so their gains are realized more quickly.
In short, Phosphatidyl Serine appears to be a completely safe and beneficial dietary supple¬ment that can offer a wide range of physical and mental health benefits. NOW® Phosphatidyl Serine is derived from soy leci¬thin, and includes Choline and Inositol – two metabolites that work synergistically to help in¬crease circulation and cognitive response.
Anti-Aging and Antioxidant Protection
December 19, 2005 09:50 AM
The most effective antiaging program is one that protects and nourishes all of the vital systems that allow us to age in the first place. Our cell structure, immune system, skin and cognition are most significantly affected by the aging process. These supplements each serve a unique purpose, and have shown great promise in providing the essentials needed to attain longevity and vitality.
December 19, 2005 09:19 AM
Phosphatidyl Serine - As we age, our natural production of Phosphatidyl Serine (PS) slows. As a result, our ability to learn, concentrate and recall memories inevitably declines. This multi-tasking phospholipid is a major component of neural membranes, and aids in the transition of impulses as well as the absorption of cognitive nutrients. PS has also been shown to inhibit the secretion of cortisol, a hormone often found elevated in individuals who are frequently stressed and depressed.*
Life Force - The Energy Activator
June 29, 2005 10:35 AM
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LIFE FORCE MULTIPLE was chosen as one of America’s most elite and comprehensive multiples, as reported in the Comparative Guide to Dietary Supplements by Lyle MacWilliam, 3rd ed. LIFE FORCE received this acknowledgement by nutrition experts because it is uniquely effective. This Bio-Aligned Formula™ goes beyond ordinary multiples that simply replace nutrients missing from the diet. LIFE FORCE provides key organ-specific nutrients to support your body’s energy generation, heart, brain, immune system, musculoskeletal system, skin, liver, eyes, and more. When all your body systems function in harmony, everything in life comes together. Your mood is positive, your mind is clear, you’ve got energy in your step—that’s your LIFE FORCE working for you.
Get Ahead with Activated Energy and a Healthy Metabolism
Your metabolism determines how much you weigh, how energetic you feel, and the effective functioning of all your systems. LIFE FORCE is a rarity – a unique multiple containing an incredible number of nutrients at the potency levels that truly support your healthy metabolic function. For example, it contains coenzyme Q10, which plays a crucial role in cellular energy production. CoQ10 is a vital intermediate in the electron transport chain, one of the body’s energy production cycles, which converts glucose, or blood sugar, into ATP (Adenosine Triphosphate), a high energy molecule that is the body’s “energy currency.” LIFE FORCE also supplies alpha-lipoic acid and the potent R-lipoic acid form of lipoic acid, which are both referred to as the universal antioxidants and important intermediaries in the Krebs cycle, another energy production cycle.
LIFE FORCE also contains tyrosine and iodine, both precursors to thyroid hormones. These hormones regulate key metabolic functions like heart rate, digestive function, weight management and energy levels. No discussion of metabolism would be complete without mentioning the B vitamins and their coenzymated forms, such as thiamin cocarboxylase, riboflavin mononucleotide, and the methylcobalamin form of vitamin B- 12. These critical vitamins and their immediately bioavailable coenzymated forms are formulated to play critical roles in thousands of enzyme reactions that promote carbohydrate metabolism, energy production, and the mental functions that invigorate and activate you as you move through your busy days. And now green tea extract with EGCG (Epigallocatechin Gallate) has been added to the formula for added metabolic support.
Protect Your Heart and Circulatory System
The amazing muscular organ that is your heart beats more than 100,000 times a day, 365 days a year, promoting vitality and alertness by constantly oxygenating our tissues. LIFE FORCE supports your cardiovascular system with antioxidant coenzyme Q10, which helps support heart muscle metabolism. LIFE FORCE also contains the minerals potassium and magnesium, electrolytes vital for healthy heartbeat and heart function, and the herb hawthorn, a rich source of antioxidant flavonoids, which has traditionally been used as a heart tonic. LIFE FORCE also supplies vitamins B-6, B-12 and folic acid to help maintain healthy homocysteine levels and vitamin K to support healthy circulation. Unlike common multiples, it supports cholesterol wellness, circulatory health and antioxidant cardiovascular protection, with both the typical d-alpha form of vitamin E but and the more potent and effective gamma-tocopherol and similarly structured tocotrienols.
Skin and Musculoskeletal Support
LIFE FORCE furnishes nutrients to build healthy bones, muscles and skin. We all know that calcium and magnesium are crucial for bone health, but many people don't know that there are a variety of nutritional cofactors that help build bone, such as vitamin D (which enhances calcium absorption and utilization), boron, manganese and copper. LIFE FORCE also supplies vitamin C and copper, necessary nutrients for collagen production (collagen is a key constituent of connective tissue in joints, skin and other areas), and the cutting-edge nutrient methylsulfonylmethane (MSM), an assimilable form of the mineral sulfur, used by the body to build and maintain connective tissues, including joint cartilage, hair, skin and nails. Additional nutraceuticals to support healthy skin include DMAE bitartrate, CoQ10, and alpha lipoic acid. LIFE FORCE also now includes rutin, quercetin, green tea extract and 65% more turmeric extract for your joint comfort.
Brain and Nerves Nutrition
The hectic pace and constant demands of life can keep our pulse racing, our nerves jangling and our temples throbbing. Our nervous systems are crying out, “Help!” LIFE FORCE provides that help. LIFE FORCE supplies the most highly bioavailable and bioactive forms of the amino acid tyrosine – the N-acetyl form and the acetyl-L form. Tyrosine is an important precursor to epinephrine and norepinephrine (collectively known as the catecholamines), which helps you respond to stress. It also contains high doses of vitamins C and B-6, required by the adrenal glands to produce the catecholamines. In addition, LIFE FORCE delivers the full spectrum of B vitamins, all important for healthy nervous system function. Now LIFE FORCE also contains a more bio-available form of tyrosine, acetyl-L-Tyrosine. And LIFE FORCE contains Neuroceutical® nutrients that support healthy brain function by furnishing DMAE and choline. Both are precursors to the important neurotransmitter acetylcholine and are important for memory focus and muscular movement. Choline is also a precursor to Phosphatidylcholine, an important constituent of the cellular membranes that surround and protect our brain cells. In addition, LIFE FORCE contains the renowned herb Ginkgo biloba and now even more grape seed extract, both effective antioxidants that can prevent lipid peroxidation, which is critically important for the high amounts of fatty tissue in the brain. LIFE FORCE—good food for the brain.
LIFE FORCE MULTIPLE supports your immune system, so you can feel your best through the seasons. LIFE FORCE contains the immunosupportive nutrient vitamin A, which fosters cell-mediated immunity and protects the epithelial linings of the respiratory and digestive tracts. Two forms of vitamin A are supplied: preformed vitamin A and its precursor, the potent antioxidant betacarotene. Other immuno-supportive nutrients in LIFE FORCE include vitamin B-6, vitamin C and zinc, which is fundamental for proper functioning of our T-cells, the “seek and destroy” cells of our immune system. LIFE FORCE also now includes 40% more lipoic acid, including the highly bioavailable alpha and R-isomer forms. Lipoic acid along with the B vitamins and CoQ10 promote building the energy reserves needed when the immune system needs to kick into high gear.
Powerful Liver Support
Your liver is responsible for converting many nutrients into their metabolically active forms before your body can use them. After activation, these nutrients travel through the blood stream to target organs where they perform their metabolic functions. Not only does the liver activate nutrients, but it also plays a crucial role in a variety of other metabolic functions, from fat digestion and cholesterol production to blood sugar regulation to the processing and elimination of toxins, an important role in today’s increasingly polluted world. For all these reasons, nourishing the liver is crucial. And LIFE FORCE does just that. LIFE FORCE contains alpha-lipoic acid, turmeric, silymarin and N-acetyl cysteine (NAC) – all potent antioxidants that support healthy liver function. NAC and alpha-lipoic acid both help produce glutathione, one of the liver’s primary detoxifying molecules. Silymarin, the active flavonoid complex of the herb milk thistle, as well as coenzyme Q10, have been shown in vitro to inhibit lipid peroxidation of cell membranes. Turmeric extract promotes bile flow and is a rich source of the antioxidant, curcumin. LIFE FORCE also contains choline and inositol, vitamin- like molecules which act as lipotropics, unique substances that prevent the deposition of fat in the liver. Since the liver is naturally high in fats, LIFE FORCE is one of the only multiples that contains the fat-soluble form of vitamin C, ascorbyl palmitate, for antioxidant protection.
Complete Antioxidant Defense
Oxidative stress is the primary cause of accelerated aging. This and other forms of free radical damage are constantly threatening your body. Whether it is from pollution, ultraviolet light, food additives, or from other sources, it is more critical than ever to protect your body with antioxidants. LIFE FORCE contains 24 of the most powerful antioxidants known to science, including eight new antioxidants based on the latest research. It contains antioxidants that are water soluble, such as quercetin and rutin, and ones that are fat soluble, such as alpha-lipoic acid and lycopene. There are antioxidants that are especially protective of specific body systems, such as lutein to protect the macula in your eye, lycopene to protect your prostate gland, and tocotrienols to protect your arteries.
Cutting-Edge Vision Nutrition
The structure and functions of your eyes are very complex. LIFE FORCE contains nutrients to help support and maintain healthy eye tissue, which is particularly susceptible to oxidative stress from free radicals. To support your healthy macula, aqueous tissue and optical nerve signals, LIFE FORCE includes ingredients such as lutein, astaxanthin, beta carotene, bilberry, zinc, lipoic acid and quercetin.
Life Force Replenishes Essential Nutrients to Support Your Low Carb Lifestyle
LIFE FORCE contains optimal levels of many nutrients that might be deficient in low carb meals. Counting carbs can lead to restrictions of nutrient-dense foods, such as dairy products, grains, fruits and vegetables. LIFE FORCE contains many of the same protective antioxidants, vitamins and minerals as fruits and vegetables, including betacarotene, vitamin C, vitamin E, flavinols, magnesium and selenium. It also contains high levels of the same vitamins found in grains, including all of the B vitamins, to support your body’s healthy energy metabolism. And it contains nutrients found in dairy products, such as calcium, potassium, vitamin A and vitamin D.
Support Healthy Fat and Protein Consumption with Life Force
Low carb lifestyles mean higher consumption of proteins and fats. Unfortunately, there are artery, heart, colon and many other health concerns associated with meals that are high in fat and protein and low in fiber and produce. However, the nutrients in LIFE FORCE can help you better process these foods when eating this way. LIFE FORCE contains high levels of protective fat-soluble antioxidants such as alpha lipoic acid, ascorbyl palmitate (vitamin C ester) and vitamin E to protect your body from the free radicals generated by consuming more fats. It also contains many nutrients for liver health, such as silymarin, CoQ10, NAcetyl Cysteine and turmeric to help support the fat metabolism your liver is responsible for. LIFE FORCE also contains a high level of the B vitamin biotin, which aids in fat, protein and energy metabolism.
Complete Energizing Nutrition
LIFE FORCE is the only multiple to target organ systems with specific nutrients and bio-botanicals, antioxidants and Neuroceuticals® for total body harmony and energy activation, system by system. Only this dedication to going deep to the cellular root of system imbalances can produce a multiple so effective that it is acknowledged in a prestigious scientific review, the Comparative Guide to Nutritional Supplements. A nutritional program with LIFE FORCE at its center can be an easy first step in joining the Wellness Revolution. The goal of this revolution is a long, healthy and fulfilling life. Allow yourself to feel your best, to achieve mental and physical harmony, to radiate energy and vitality. Feel your LIFE FORCE!
ALPHA GPC - Improves Mental Performance
June 28, 2005 06:21 PM
The quality of our life experience—and our ability to live life to the fullest—is a direct result of optimal brain function. Only a few years ago, nothing could be done to stem the tide of poor circulation, forgetfulness and “mental fog.” But neurological science exploration has identified a fundamental brain compound critical to attention, learning, memory, and even the higher cognitive functions of reasoning and intuition. Research confirms that L-alpha-glycerylphosphorylcholine (called Alpha-GPC for convenience) is crucial to neuronal function and structure. Derived from purified soy lecithin, Source Naturals ALPHA-GPC readily converts to acetylcholine in the brain, helping to maintain neuronal structure integrity. Source Naturals provides an easy and convenient means to profoundly impact the very nexus of our body and mind.
GPC Is Unique
No other nutritional compound comes close to GPC in its ability to boost critically important acetylcholine levels. Found in both the brain and the peripheral nervous system (including the nerve-muscle junctions), acetylcholine is a key nerve messenger molecule, or neurotransmitter. Aging brains are characterized by functional deficiencies in both acetylcholine and its cholinergic receptors. GPC is a highly bioavailable supplement that boosts acetylcholine levels to improve cognitive function. It is also a major choline reservoir, helping to protect the brain against damage from poor circulation and potentially toxic metabolites.
Deficiencies in acetylcholine can cause the body to break down Phosphatidylcholine for its choline content, leading to the death of brain cells. Yet in controlled clinical trials of middle-aged subjects taking GPC, reaction time was enhanced and there was improved energy generation and electrical coordination in the brain. For older subjects, double-blind trials demonstrated that GPC had superior benefits over certain other brain nutrients for mental focus, recall, verbal fluency—a unique, marked overall enhancement of mental performance. GPC is an example of what the great Linus Pauling referred to as “orthomolecules,” that is, molecules that are “orthodox” or “correct” for the body. GPC excels as a protective nutraceutical for memory loss and mood enhancement. It protects cells of the brain (and other organs) from damage, shielding a range of important biomolecules against toxin build-up.
Extensive Clinical Testing
In clinical trials that involved more than 5,000 patients, GPC showed marked improvement in overall brain performance. Depending on the particular trial, 50-70 percent of the patients who received GPC had their mental functions improved to a degree “meaningful to life quality.” GPC has shown revitalizing effects on the declining brain, and preliminary evidence suggests GPC may act on the pituitary gland to partially restore its capacity to make vital for cell maintenance and longevity. Other unique brain features of GPC are its benefits for attention and recall in young healthy adults, and its superior bioavailability. GPC readily crosses the bloodbrain barrier to raise brain choline levels within a few hours following oral intake. GPC helps with body-mind integration by being a ready reservoir for acetylcholine. This neurotransmitter is ubiquitous in brain circuit maturation, expansion, renewal and repair, as well as in the “agility” or adjustments of the circuitry that occur during adult life. In addition, an animal study has shown that GPC increases the release of GABA (gamma-aminobutyric acid), the most important and abundant inhibitory neurotransmitter in the brain. It acts as a “balancer” for the brain and helps induce relaxation and sleep. Without sufficient GABA, neurons fire at random, unable to make sense of incoming signals. GABA helps minimize “neural noise,” making it easier to focus and concentrate.
Why you should take GPC:
How Does CLA Work?
June 22, 2005 09:46 PM
How Does CLA Work?
How could CLA hinder the growth and development of certain cancers in animals? Scientists have developed some intriguing possibilities, and many of them are related to the theory of antioxidants.
WHAT IS AN ANTIOXIDANT?
Well, one of the ironies of life is that oxygen, so essential to human life, also causes decay. Look at the parts of your car where paint may have pealed away, and you will notice rust, what scientists call oxidation. Molecules of oxygen combine with the iron or chromium on your car and change its chemical alignment to iron oxide or chromium oxide—rust. In a very real sense, the same thing happens to you as you age. Inside your cells, thousands of chemical reactions take place each moment. These reactions break apart the long chains of carbon, oxygen and hydrogen that make up body tissues and combines them in new ways. Some of those combinations cause decay. One example is when a free radical—a single atom of roaming oxygen—attaches itself to something useful, rendering it useless or even dangerous. If a free radical were to change DNA, for example, that could mutate a cell. This free radical process is one way this oxidation occurs, and antioxidants, often called free radical scavengers, attach themselves to the free radicals, blocking their damage. This can help improve life and help to cut the problems of oxidation. Indeed, many see antioxidants as a way of lessening the risks of cancer.
Many people know about important antioxidants, such as ascorbigen (vitamin C), selenium or alpha tocopherol (vitamin E), but nature provides numerous antioxidants. Many exciting ones are emerging, such as proanthocyanidins (often known as pycnogenol), quercetin (common in many fruits) and selenium (a mineral). C LA may be another antioxidant emerging from the research. Dr. Pariza and others found in a 1991 experiment that in the test tube, CLA was effective in battling free radicals. 28 It helped prevent damage to the DNA inside the cells. Pariza says in another paper, “Our hypothesis is that the antioxidant activity of CLA may at least in part explain its anticarcinogenic effect.”29 That would mean that one way CLA prevents cancer is because it blocks these dangerous free radicals. (Other theories about how it fights cancer include breaking down the chemicals that cause cancer into others that don’t .30 All the theories may be true in specific situations, and none might.) But like many other emerging, exciting areas of scientific inquiry, this idea that CLA is an antioxidant has doubters. Researchers J.J. van den Berg, N.E. Cook and D.L. Tribble wanted to see if CLA protected fatty membranes comprised of a substance called palmitoyl-2-linoleoyl Phosphatidylcholine (PLPC) from the damage of biologic oxidation. In research published in 1995, they compared CLA’s effect to the wellknown antioxidant vitamin E. While vitamin E protected well, CLA did relatively little. They also found that CLA did not become a mineral chelator, an agent that helps natural minerals become available biologically. They bluntly said, “On the basis of our observations, a role for CLA as an antioxidant does not seem plausible.”31
Another study in 1995, however, showed that CLA can break down into other substances, called feran derivatives, that do act as antioxidants.32 As in all emerging sciences, debates ensue among honest, dedicated researchers. CLA may not, itself, be a antioxidant. Perhaps it acts as antioxidant in only certain situations. Perhaps things that come from CLA act like antioxidants. That is the state of the research today. (Indeed, Dr. Pariza says such debates are common in the field of antioxidants. 33)
What is important to remember is that in numerous animal models, CLA protected against the dangers of many different kinds of cancer in animals, and that, according to scientists, it is one of the most potent cancer-preventing substances of its kind known to science. Whether the cause of this effect was because of CLA or because of some other reason really isn’t that important.
Another thing to remember is that CLA is not a cancer drug. It is something that would be useful in addition to other cancer treatments. It is something to consider to lower your risks and, perhaps, lessen the effects of treatment. It should not be considered a treatment option on its own.
Thanks for the Memory
June 11, 2005 03:49 PM
Thanks for the Memory by Estelle Sobel , February 6, 2002
Thanks for the Memory By Estelle Sobel
"I feel like every day, I lose my memory more and more. It started when I couldn't find my car keys, sometimes I forget directions. My mother has Alzheimer's so I'm concerned," says Jerry Solowitz, a 63 year old man.
Ellen Lerner, 37, sometimes worries that she can't keep track of everything in her job as a public relations executive. "I feel like stress can get to me easily, and I worry because I forget simple things like where I put a file."
Should these people be concerned?
"Yes," says Lynda Toth, Ph.D., co-author with Pavel Yutsis, M.D., of Why Can't I Remember? Reversing Memory Loss (Avery, 1999).
Jerry should start a specific program with a health practitioner who specializes in memory loss, due to lots of unsuspected new causes for memory dysfunction. Ellen needs to make lifestyle changes, as stress can definitely lead to memory loss.
"Cortisol, which is one of the stress hormones, can be harmful because it keeps calcium in the memory pathway too long and destroys the neurons, which is very damaging to the brain," notes Toth.
Why Does Memory Fail?
Memory fails for several reasons, says Augustine DiGiovanna, M.D., author of Human Aging: Biological Perspectives, (McGraw-Hill 2000), and Professor of Biology at Salisbury State University in Salisbury, MD.
Normal Aging: Much of diminished memory as we age is due to reduced blood flow to the brain from atherosclerosis, which is hardening and narrowing of the arteries. Decreased blood flow causes neurons to shrink and function less effectively.
Also, as we age we lose neurons and neuron connections that can lead to memory loss. So the way people think, how much they remember, and the mental activities they do determine how many brain cells survive through the years.
Finally, as people live longer, the chance is greater that the body's immune system and other defense mechanisms won't be able to protect against certain diseases that affect the brain and memory (Parkinson's, strokes, Alzheimers, atherosclerosis).
A Starving Brain: The brain is not getting fed the nutrients it needs (vitamins, minerals, amino acids, glucose). Without the right "food" the brain's energy levels become lowered and stop powering the memory cells. Then, free radicals can do more dirty work and continue to rust memory cells.
Drink And Sink: Alcohol passes through the blood-brain barrier and slows down the processing of information between memory neurons. Memory loss increases over time, as memory tissues shrink.
Sad Stories: Depression can imbalance the neurotransmitters and electrical charges of neurons.
Tense and Tight: High blood pressure can constrict and narrow blood vessels, limiting blood and oxygen flow to the brain.
One way to boost brain power is to take the right supplements.
Ginkgo biloba: The powerful medicinal herb ginkgo biloba increases blood flow and circulation to the head by dilating blood vessels in the brain, allowing more oxygenated blood to get to the neurons. It also protects against free radical damage.
Research: Ginkgo biloba extract displayed a significant effect on helping the mental abilities of people 50-59 years old (Phytotherapy Research 13, 1999: 408-415).
Pregnenolone: This powerful hormone regulates the balance between excitation and inhibition in the nervous system and helps enhance memory and brain function, possibly by repairing a fatty substance that is part of the myelin sheath that surrounds nerve cells. Research: A St. Louis University School of Medicine study on mice showed that pregnenolone enhanced memory and helped mice to navigate mazes better.
Huperzine A: This herbal supplement is derived from club moss found in China; in purified form it inhibits the enzyme that breaks down acetylcholine, a neurotransmitter produced in the brain that you need for memory.
Research: Studies conducted by Alan Mazurek, M.D., found that huperzine A in purified form improves memory, enhances focus and concentration and has been used to improve memory loss in Alzheimer's patients (Alt. Ther. in Health Med. 5 , March 1999: 97-98).
Another study in The Journal of Neuroscience Research showed that huperzine A is a potent inhibitor of cholinesterase, which penetrates the brain and produces a dose-dependent increase of the neurotransmitters acetylcholine, norepinephrine and dopamine in rat cortex (41, 1995: 828-835).
Phosphatidylserine (PS): This substance, which occurs naturally in nerve cell membranes, helps keep fatty substances soluble and cell membranes fluid and helps reduce levels of cortisone which are damaging to tissues.
Research: Phosphatidylserine encourages a sense of calm by raising the levels of alpha brain waves and increasing the production of acetylcholine (Neuropsychobiology 24, 1990-1991: 42-48).
Vitamin E: This potent antioxidant attaches to bad cholesterol and helps prevent free radical damage to cells.
Research: Age-related processes like memory function and problem solving can be affected by free radical damage. Several studies show that vitamin E might slow the effects of Parkinson's disease and Alzheimer's disease (JAMA 282, August 18, 1999: 621). Acetyl-l-carnitine: Increases cognitive performance because it rejuvenates cellular membranes of mitochondria, the storehouses of energy contained in every living cell.
Alpha-Lipoic Acid: Preserves memory tissue by increasing glutathione levels, which protect fat stores in neurons from being damaged.
Nine Ways to Remember
Dr. Lynda Toth suggests the following ways to make the most of what you've now got.
1) Power Up Your Smile. Remove dental fillings and replace them with porcelain or ceramic ones. The mercury in metal fillings may be harmful (some believe) and can affect the brain and nervous system, inflaming memory tissue and preventing the entry of nutrients into the cells.
2) Don't Be a Tin Man/Woman Avoid exposure to aluminum. Don't use aluminum pots to cook in. Aluminum accumulates in memory tissue, damaging cells. In fact, autopsies of Alzheimers patients show they have unusually huge amounts of aluminum in the brain. But no one knows where this aluminum comes from.
3) Eat Right. Eat organic and pesticide-free foods. Pesticides get into the cells and can damage DNA.
4) A Matter of Taste. Avoid foods with artificial coloring, monosodium glutamate (MSG, often called "natural flavors" or "natural seasoning"). Also avoid processed foods with taste enhancers called exito toxins such as l-cysteine and aspartic acid.
5) In the Raw. Make sure that your diet consists of enzyme-rich 50% raw foods (fruits and vegetables) to feed the brain. Eat less animal fats.
* Drink green juices to support levels of the brain's clean-up enzymes.
*Eat lots of fiber, which helps remove toxins from the body. Pick up psyllium fiber.
*Limit intake of processed sugar, caffeine and alcohol to lessen the load on the liver and pancreas.
6) Cut Bait. Watch the fish that you eat. Lots of ocean and inland-caught fish are contaminated with mercury. Go for deep, cold water fish such as cod. Avoid shark and swordfish.
7). Oil Up. Supplement your diet with omega-3 fatty acids, such as cod liver oil or flaxseed oil. These fats lubricate memory cells.
8) Work That Body. Stay fit and exercise. Exercise helps oxygenate the body, reduces cholesterol, and builds and energizes new memory cells which reduces wear and tear on the brain function.
9) Do Mind Games. Read, listen to music. Tune into different radio stations than the ones you normally listen to. Do crossword puzzles and a wide selection of word games which can stretch your brain and give it a tough workout.
Student of Life
You need to keep learning your whole life to keep your brain and memory in tip top shape. The brain is adaptable, and you are always building new neurons, says Dr. Toth, which means that there is no limit to how long it can develop. Anything that stimulates the brain will help it to grow. That's why as you get older it's even more important to take classes, start a new hobby, travel. In fact, the challenge of learning and doing new things (without stopping in a fit of frustration) causes your brain to grow, says Dr. Mazurek.
The Good News
As people get older, their brains may actually improve and repair themselves through a complicated process that is designed to eliminate faulty neurons that are prone to making mistakes. At the same time, brain activity goes on that results in the development of new and improved connections with neighboring neurons.
Research also shows that memory improves if you train people to have faith in themselves. (The brain helps those who help themselves.) Apparently, a confident perspective can encourage the brain to actually improve to the point where its new-found abilities may increase to the point where it fulfills expectations.
So keep your chin up and stay away from the artery-clogging saturated fat that can cut off the brain's blood supply. It's all in the attitude, says Dr. DiGiovanna. And, of course, the key to a long and happy life with your brain is also on the end of your fork and in that bottle of supplements.
Estelle Sobel, is the co-author of Beautiful Skin: Every Woman's Guide to Looking Her Best at Any Age (Adams Media, May 2000).
Improove Memory ...
June 09, 2005 05:49 PM
Mesmerizing Memory by Cal Orey Energy Times, January 1, 1999
In the 60s, the same rock 'n' rollers who belted out "One pill makes you larger and one pill makes you small," often espoused the belief that certain pills could expand the mind. While counter-culture pill purveyors were pilloried for their pill-popping claims, 90s nutritional research has uncovered a stash of supplements that may amplify mental improvement.
Like a blues singer bending a high note, researchers are now humming with dramatic assertions that certain nutritional supplements can sustain and enhance concentration and memory function. For instance, studies reveal possible benefits for cognitive powers from vitamin C, magnesium and Ginkgo biloba. A recent report in the Journal of the American Medical Association (JAMA 278:1327-1332) said that an extract of Ginkgo biloba "can stabilize and, in some cases, improve the cognitive function and social behavior of demented patients."
A researcher in the Proceedings of the National Academy of Sciences noted that a daily dose of vitamin E may "help protect the brain and its memories from the ravages of time." And the beat goes on: other evidence indicates that zinc, iron and boron may pump up short-term memory attention span and cut the time it takes to perform mental tasks.
Lester Packer, PhD, professor of molecular and cell biology at UC Berkeley, told a joint 1996 United Nations-World Health Organization conference on Aging that "there is a growing body of evidence indicating that the free radical theory of aging and aging-related disease is valid," and that dietary and supplemental antioxidants can help fight illness and mental deterioration.
Vitamin E and other memory aids are believed to protect brain chemicals called neurotransmitters, "the ferrymen of the brain's communication system," that influence concentration and memory. Experts say that sustaining the level of these nerve chemicals in the brain can potentially improve all mental processes.
Too much alcohol, for example, commonly causes progressive mental decline, according to Secrets of the Superyoung (Villard) by David Weeks and Jamie James. The authors also point out that "the memory tends to worsen noticeably after 15 years of alcohol drinking, and much sooner in people who go on massive binges."
"The effects of cigarette smoke are subtler because the poisonous effects of carbon monoxide in each puff are temporarily offset by the alerting effects of the nicotine," they add. Can't remember the name of that singer cavorting in a music video? Tests have shown that smokers are worse at connecting peoples' names to their faces than nonsmokers.
n Learn something new: A second language, musical instrument, or unique puzzles and games keep neurons working like new.
n Turn off the TV: Read. Studies show that passively watching TV requires less concentration than eating cereal. Mental rejuvenation also requires physical activity. Exercise increases oxygen flow to the brain, which supports memory, concentration and cognition. One study has shown that exercise significantly brightened the moods of middle-aged and older women, regardless of whether they were pre- or post-menopausal, with or without hormone replacement therapy.
Supplemental Brain Help
Antioxidants, including the previously mentioned vitamin E (You haven't forgotten vitamin E already, have you?), provide crucial help for vigorous cerebral function. The free radicals created by tobacco smoke, air pollution, ultraviolet light and certain carcinogenic chemicals deconstruct cell membranes and may foster microscopic brain cell havoc. Antioxidant enzymes convert free radicals to more neutral, benign substances and nutritional antioxidants can neutralize free radicals by linking up with them.
Vitamin C, a brainy antioxidant all star, performs so well that, according to Dr. Khalsa, its levels in the brain are almost 15 times higher than in other parts of the body. This nutrient, he asserts, aids mental and physical longevity. In a UCLA study, people who ingested at least 300 mg of vitamin C daily lived more than six years longer than those who ingested less.
Added to this mix, magnesium also scavenges free-radicals, according to Dr. Khalsa. Plus, experts recommend grape seed extract (phytochemicals that protect a wide range of cellular structures) to safeguard nerve cells and mental capacity.
B Vitamins for the Mind
Boron plays a crucial part in mental function. Scientists at the USDA's Human Nutrition Research Center have linked boron deficiencies to chronic lethargy and fatigue. In brain studies, they found that the electrical activity of the gray matter in the boron deficient indicated increased drowsiness and mental sluggishness.
HupA basically protects the brain from free radical damage (due to low levels of antioxidant defenses) and maintains or enhances crucial neurotransmitter action. More specifically, HupA helps reduce the breakdown of acetylcholine, the vital neurotransmitter, and makes this substance more bioavailable. In addition, HupA helps make choline accessible to the brain for the synthesis of acetylcholine, according to a study in Neuropharmacology (30, 1991: 763-768).
Normally, the brain manufactures sufficient levels of the chemical Phosphatidylserine, a lecithin-derivative that helps boost neurotransmitter release, but deficiencies of vitamin B12 and folic acid, or of essential fatty acids, may retard that production. Low levels of Phosphatidylserine in the brain are related to impaired mental function and depression in the elderly. Scientists reporting in Aging (5, 1993; 123-33) describe "good results" using Phosphatidylserine in the treatment of age-related cognitive ills.
Ginkgo Brain Power
Another ingredient in what seems like an alphabet-soup of brain nourishment is DHA (docosahexaenoic acid), an omega-3 fat essential for normal brain function. Researchers met recently at The New York Hospital-Cornell Medical Center's Nutrition Information Center to discuss "Keeping Your Brain in Shape: New Insights into DHA." Their findings revealed links between low levels of DHA and Alzheimer's, depression, memory loss, attention-deficit/hyperactivity disorder (ADHD) and certain behavioral traits including aggression and hostility.
Researchers from the National Institutes of Health point out, however, that fish is an excellent dietary source of DHA. In their studies, they discovered that depression rates in Japan and Taiwan, where fish ranks a top spot on the menu, are significantly lower than in North America and Europe.
DHA also is crucial to the neurological development of children, according to findings published in Pediatrics (vol. 101, no. 1, January 1998). Researchers suggest that DHA-rich breast milk should be the model for infant formulas that enhance babies' neurological development. Scientists also have correlated some behavioral problems in children-ADHD, for example-to DHA deficiencies.
If you are a vegetarian, or have other cause for concern about a potential lack of DHA in your diet, you can rely on dietary supplementation of DHA. Bruce J. Holub, PhD, of the University of Guelph in Canada provided vegetarians in his research project with DHA supplements over a 42-day period and substantially increased their DHA blood levels.
The bottom line to enhanced mental performance is to take a balanced approach, says Robert Snider, MD, who specializes in preventive medicine in Massena, New York. "Maintaining brain power includes exercise, stress reduction and good nutrition." The message to keep in mind: Don't lose your nutritional balance or you could lose a piece of your peace of mind.
Recommended Reading: & Brain Builders (Reward Books, 1995), by Richard Leviton.
Brain Longevity (Warner Books, 1997), by Dharma Singh Khalsa, MD.
Omega 3 Oils to Improve Mental Health, Fight Degenerative Diseases and Extend Life (Avery, 1996), by Donald Rudin, MD, and Clara Felix.
Successful Aging (Pantheon, 1998), by John W. Rowe, MD, and Robert L. Kahn, PhD.
Essential Fatty Acids - Lipids, Cell Memgranes & Eicosanoids
June 09, 2005 09:35 AM
Essential Fatty Acids and Phospholipids
Essential fatty acids & phospholipids are primary constituents of cell membranes, and as such they are vital to the makeup of the human body. Essential fatty acids are used to generate certain intra-cellular hormone-like substances, including prostaglandins and leukotrienes, which are responsible for regulating key bodily processes. Source Naturals essential fatty acid supplements are potent, effective and chemical-free.
LIPIDS, CELL MEMBRANES & EICOSANOIDS
Almost by definition, life is composed of cells, and cells are defined by membranes. One theory suggests that, around four billion years ago, self-replicating molecules, similar to the ribonucleic acid or RNA in our own cells, were synthesized from organic molecules. These self-replicating molecules adapted to changes in their environment to increase their potential for survival. Thus began the process of evolution that has led, over the eons, to us. One turning point was when these molecules developed membranes - envelopes which could help concentrate chemicals needed for the cell's survival. There existed in the "primordial soup" substances uniquely suited to this purpose: a class of organic compounds we call lipids . Lipids are more commonly called fats, and in this health and image-conscious age people often think of them as something to be avoided. However, the word fat refers to a variety of substances with a diverse range of chemical properties, which are essential for survival and well-being . The simplest lipids, fatty acids such as palmitic acid, consist of a hydrocarbon "tail" connected to a carboxyl group (COOH). The majority of lipids in food and in the human body occur in the form of triglycerides - a molecular configuration in which three fatty acid chains are attached to a 'backbone' of glycerol (an organic alcohol composed of a 3-carbon chain with an alcohol group attached to each carbon). The major roles of lipids can be described as energy and storage, structural, and metabolic.
Energy and Storage
Molecules can contain more or less chemical energy. In living systems most of the energy needed to drive chemical reactions is derived from oxidation. Oxygen, the ultimate electron acceptor, is a strong oxidant: it has a marked tendency to attract electrons, becoming reduced in the process. When a molecule undergoes a chemical reaction from a high-energy reduced state to a low-energy oxidized state, energy is released. This is what happens in a fire: the high-energy carbohydrates in wood, such as glucose, react with oxygen, releasing heat and the low-energy molecules of carbon dioxide and water. This is similar to what happens in metabolism.
Most of the carbon in a fatty acid chain is highly reduced, which makes fats more energy-rich than the other organic molecules that can be burned as food. This is what we mean when we say fats are high in calories - a measure of the amount of energy released when a substance is oxidized. Fats contain more than twice as many calories as carbohydrates. This makes fats an important storage fuel for most of the body.
Another important class of lipids in the human body consists of the phospholipids. Like triglycerides, phospholipids contain fatty acid chains- in this case two, one saturated and one unsaturated, attached to a glycerol backbone. Unlike triglycerides, in phospholipids the third carbon of the glycerol molecule is attached to a phosphate (a molecular group that contains phosphorus and oxygen), which is in turn attached to either an amino acid or, in the case of Phosphatidyl choline, a molecule of the B-vitamin - like substance, choline.
Their unique molecular structure makes phospholipids amphipathic, which means 'likes both':
Fats, being hydrophobic, tend to separate out from water. When fat is mixed with phospholipids in the presence of water, the phospholipid molecules attach themselves to the molecules of fat and bring them into the water solution, enabling the fats to dissolve in water.
Phospholipids form a structure called a lipid bilayer, a two-ply sheet of phospholipid molecules in which the hydrophilic head groups face outward and are in contact with the water, and the hydrophobic tails face each other on the inside of the bilayer. This structure is one of the key constituents of the cell membranes that surround every living cell.
The lipid bilayer of cell membranes is a fluid in which membrane-embedded proteins "float." These proteins serve a wide variety of different functions. Some are enzymes, serving to carry out chemical reactions in the adjacent solution. Some are involved in signaling, in which a biochemical action in a cell is 'commanded' by means of a hormone or some such other signaling molecule. Still others are involved in transporting substances across the membrane, into or out of the cell.
The functions of membrane-embedded proteins are dependent on a very precise balance of phospholipids for their function. Phosphatidyl serine, for instance, has a negatively-charged head group that associates preferentially with a class of membrane-bound proteins called ATPases. ATPases regulate, among other things, the balance of sodium and potassium in intra- and extracellular fluids, a balance that is necessary for the integrity of our cells and also for the electrochemical impulses that make up our thoughts and feelings. Without Phosphatidyl serine, these vitally important membrane-embedded proteins could not function.
Cholesterol is a waxy substance that is essential to the structure of cell membranes, which depend for their function on a delicate balance between fluidity and solidity. Cholesterol provides a semifluid matrix, as well as enhancing membrane fluidity. About 80% of the cholesterol the body uses is manufactured by the liver; the other 20% is consumed in food. Elevated blood cholesterol levels are associated with heart disease. Saturated fats are converted into cholesterol more readily than unsaturated fats, and polyunsaturated fats usually depress blood cholesterol concentration to some degree. Researchers have thus recommended that people lower their consumption of saturated fats and increase their consumption of polyunsaturated fats. A process called hydrogenation , in which hydrogen molecules are added, is used to harden these unsaturated fats to create solid spreads, such as margarine. This process causes formation of altered fats called trans fatty acids. Although the results are not conclusive, human and animal studies have pointed to possible deleterious effects from consumption of trans - fatty acids, which are estimated to account for 5.5% of all fats consumed by Americans. These studies include one in men and women that showed harmful effects of trans - fatty acids on blood cholesterol ratios.
When each link of a fatty acid chain contains an atom of hydrogen, as in palmitic acid, that fatty acid is said to be saturated . If two carbon links are double bonded to each other, each has one less hydrogen atom, and the fatty acid chain is said to be unsaturated. If a fatty acid contains one double bond, it is said to be monounsaturated, and if it has two or more double bonds it is said to be polyunsaturated . Certain polyunsaturated fatty acids cannot be manufactured by the body and must be obtained from the diet. These nutrients are called essential fatty acids and are necessary for the normal function of all tissues. The essential fatty acids fall into two categories:
In addition to being phospholipid precursors, essential fatty acids can be converted to a class of hormone like intracellular messengers called eicosanoids. The physiologic effects of eicosanoids are potent in minute quantities. Their effects are so powerful that they need to be produced near the site of their action and are quickly inactivated. The important eicosanoids include the thromboxanes, leukotrienes and prostaglandins (PGs ). Prostaglandin molecules consist of a five-carbon ring with two side chains. They can be distinguished from each other by numbers that refer to the number of double bonds in their molecular side chains: 1-series PGs have one double bond, 2-series have two double bonds, and so on. Prostaglandins mediate a variety of bodily processes, including inflammatory reactions, blood vessel contraction and dilation, and platelet aggregation. The different PGs have different effects on the body, and different essential fatty acids act as precursors for different PGs.
Important essential fatty acids in humans are the omega-6 fatty acids, which include linoleic acid (LA), gamma-linolenic acid (GLA), and arachidonic acid (AA). 1-series PGs are derived from GLA and tend to cause blood vessels to dilate and reduce the stickiness of platelets (cell fragments in the blood that help initiate blood clotting). 2-series PGs are derived from arachidonic acid and tend to increase platelet stickiness and cause blood vessels to constrict. Meat and dairy products are dietary sources of the PG2 precursor, arachidonic acid; American diets tend to be rich in these foods. The rate-limiting step for production of GLA in the human body is an enzyme called delta-6-desaturase (D6D). The action of this important enzyme can be blocked by a number of different lifestyle factors, including a diet high in saturated or trans- fatty acids and chronic alcohol consumption. A modest increase in consumption of GLA will significantly increase the ratio of GLA to AA in the tissues, which may have a beneficial effect on the homeostasis of the cardiovascular system. Supplementation with omega-3 fatty acids, such as flaxseed oil or fish oil, is beneficial for similar reasons. Omega-3 fatty acids are precursors for 3-series PGs, which reduce platelet stickiness. Series-3 PGs also tend to inhibit conversion of AA into its metabolites, the 2-series PGs.
The lipid composition of our diets has changed radically in the 20th century. Our intake of saturated fats has increased dramatically, and trans fatty acids, which did not exist before the advent of modern food processing technology, now form a major part of our diets. We eat less fish and green leafy vegetables, important sources of omega-3 fatty acids, than our ancestors did. Far from being an inert, homogeneous substance, fat is dynamic and varied - a subtle and interactive matrix for many of the biological processes taking place in our bodies, minute by minute.
PHOSPHATIDYL SERINE (PS) - Maintain healthy cells ...
June 04, 2005 11:08 AM
All we have ever known or will ever feel, begins and ends with the hundreds of billions of nerve cells that form our brain. Without them, there can be no experience; for us, nothing would exist. Our mind and personality, the sense of who we are, emanate from this immensely intricate system of nerves. The brain’s remarkable ability to perceive and perform, remember and learn, is severely challenged by today’s social and physical environment. These environmental factors accelerate the decline in nerve cell activity that normally occurs with age. Recent clinical research is revealing how previously unrecognized nutrients can strengthen the body’s natural defenses against age-related cognitive decline. Source Naturals is proud to present the latest breakthrough in nutritional support for the brain: Phosphatidyl SERINE.
Phosphatidyl Serine (PS) is a phospholipid which forms an essential part of every human cell, but it’s particularly concentrated in the membranes of nerve cells. Since the electronic messages that communicate and regulate every aspect of our lives travel along nerve cell membranes, the structural integrity of these membranes is imperative to our health. The nerve cell membrane is the site where molecules of sodium and potassium exchange electrons, causing the electrical impulse to be generated. This bio-electric current then travels along the membrane to trigger the release of neurotransmitters. These are the chemical messengers that cross synapses (gaps between nerve cells) to relay information to neighboring nerve cells. This sets other electrical currents in motion– along thousands of other nerve cells. This happens billions of times each second, and is how the brain and nerves coordinate and communicate with the rest of the body. PS has a very important function in the nerve cell membrane. As a key bio-structural molecule, PS provides vital support for the membrane proteins that enable nerve cells to communicate and grow.
Regulating the Flow
Unlike other cells in the body, nerve cells do not reproduce. Instead, they repair and rebuild themselves, using proteins called Nerve Growth Factor (NGF). Experiments verify that PS enhances the synthesis and reception of NGF, which tend to drop off radically with age.1 PS supplements enhance the cerebral cortex’s output of acetylcholine, the neurotransmitter associated with our ability to think, reason, and concentrate. PS also stimulates the synthesis and release of dopamine, related to heightened states of attention.2 The brain’s response to stress also appears to be related to PS. When healthy young men were subjected to exercise-induced stress, those taking PS had a lowered stress response. This was measured by blood levels of ACTH, the pituitary hormone that triggers the adrenals to secrete the stress hormone cortisol.3
Subjects taking PS showed increased levels of brain energy metabolism and scored higher on cognitive tests.4 Behavioral factors were also measured in elderly subjects; PS positively affected their mood states.5 Over 23 clinical trials have investigated the effect of PS supplements on more than 1200 human subjects, ages 40-93. Consistent and statistically significant results suggest that PS supports brain functions that tend to diminish with age.
Nutritional research continually reveals new potentials for wellness. Source Naturals is committed to helping people achieve a fulfilling life, and a fully functioning nervous system is central to this aim. Source Naturals Phosphatidyl SERINE can help support your body’s natural regenerative processes, keeping your brain healthy and vital for a long, long time. Experience the difference with Source Naturals Phosphatidyl SERINE.
Mental Edge - Support proper Brain Function...
June 03, 2005 06:07 PM
Aging and nutritional imbalances can disrupt the multiple body systems that affect healthy brain function. The result: cognitive symptoms* such as forgetfulness, inability to focus, and mental fatigue. MENTAL EDGE® is a Bio-Aligned Formula™ that supports the interdependent body systems involved with healthy brain function. These include neurotransmitter production, myelin sheath generation, stress response, energy metabolism, and antioxidant defense.
Mental Edge®: A Bio-Aligned Formula™
Many scientists believe that only a small portion of the brain is fully utilized. MENTAL EDGE is a literal multivitamin for your brain. This comprehensive herbal-nutrient formula optimizes brain function by addressing the multiple body systems involved with cognitive health.
Neurons (nerve cells) communicate with each other when neurotransmitters (brain chemicals) cross a small gap called a synapse to convey a message from one neuron to the next. Second messengers help transmit the message from the membrane of a receiving neuron to its inner environment. MENTAL EDGE supports neurotransmitter production with L-glutamine, L-phenylalanine, L-pyroglutamic acid, taurine, L-tyrosine, manganese, vitamins B-1 and B-6, and inositol.
Acetylcholine is one of the most important neurotransmitters. It is vital for memory and muscle movement. The ingredients DMAE, Phosphatidylcholine, L-pyroglutamic acid, vitamin B-5 and choline are precursors to acetylcholine. DMAE is particularly important because it crosses the protective blood-brain barrier more easily than the others. DMAE also enhances mental concentration.
Adaptogenic herbs help provide the brain with the support and energy it needs to deal with the physical and mental stresses of an ever-changing environment. MENTAL EDGE supports stress response with the botanicals gotu kola, schizandra, and Siberian ginseng, and with the nutrients taurine, calcium, magnesium, potassium, vitamins B-5 and C, and inositol.
Just as every cell needs the proper nutrients to survive, so do neurons. The brain accounts for 2% of our body weight, yet uses 15% of our total energy supply. Adequate levels of energy-generating nutrients are vital to the high-powered functioning of this organ. MENTAL EDGE supports energy generation with ginkgo biloba, L-glutamine, calcium, magnesium, manganese, potassium, zinc, B-vitamins, biotin and folic acid.
Myelin Sheath Generation
Myelin, composed of fat and protein, makes up the myelin sheath that forms a protective insulating covering around certain nerve fibers. Properly formed myelin increases nerve impulse conduction. MENTAL EDGE contains vitamins B-5 and B-12, which are needed for myelin sheath generation.
Lifestyle Tips for Cognitive
Health: A Strategy for WellnessSM Eat Well: Recent research suggests that diets rich in beta-carotene and vitamins C and E help reduce memory problems, probably by lessening oxidative stress. And new animal research at the University of Toronto found that a highfat diet slowed the ability of rats to learn new tasks. Use Your Brain: Learn a foreign language or new hobby, do crossword puzzles, read books, and cut back on TV. Scientists at Case Western found that people who were less mentally active in middle age were three times more likely to experience memory decline as they got older. Stay Active: Vigorous walking can improve mental processes in aging individuals, according to research. Aerobic exercise increases oxygenation and blood flow to the brain, resulting in improved memory, organization, and the ability to juggle intellectual tasks. Manage Stress: Long-term anxiety or depression can make a person more forgetful. Try to regulate stress, increase social contacts, and, if necessary, seek professional help. Get Organized: Make the most of your cognitive abilities through the use of memory aids such as “to-do” lists, notes, or calendars.
Neurotransmitter Production: L-Glutamine, L-Phenylalanine, L-Pyroglutamic Acid, Taurine, L-Tyrosine, Manganese, Vitamins B-1 & B-6, Inositol
Acetylcholine Production: DMAE, Phosphatidylcholine, L-Pyroglutamic Acid, Vitamin B-5, Choline
Antioxidant Defense: DMAE, Ginkgo Biloba, Zinc, Vitamin C
Stress Response Gotu Kola, Schizandra, Siberian Ginseng, Taurine, Calcium, Magnesium, Potassium, Vitamins B-5 & C, Inositol
Energy Metabolism: Ginkgo Biloba, L-Glutamine, Calcium, Magnesium, Manganese, Potassium, Zinc, Vitamins B-1, B-2, B-3, B-5, B-6, & B-12, Biotin, Folic Acid
Myelin Sheath Generation: Vitamins B-5 and B-12
Mega Mind - re-align your body systems ...
June 03, 2005 05:24 PM
Aging and nutritional imbalances can disrupt the multiple body systems that affect healthy brain function. The result: cognitive symptoms* such as forgetfulness, inability to focus, and mental fatigue. MEGAMIND™ is a Bio-Aligned Formula™ that helps align multiple systems: neurotransmitter production, antioxidant defense, energy generation, circulation, and myelin sheath generation. Complementary Formulations Source Naturals can help keep your mind sharp and alert. Use MENTAL EDGE® Bio-Aligned Formula for foundational support, or MEGAMIND, when memory symptoms* are severe. HIGHER MINDTM is an additional Bio-Aligned choice. Take these formulas alone or as the core of a program that includes additional ingredients such as DHA (NEUROMINS®), GINKGO-24™, Phosphatidyl SERINE, VINCAMINE, and VINPOCETINE.
In today’s complex world, we are bombarded with information. Our ability to process this massive input depends on how well we nourish the multiple body systems related to brain health. In addition, normal aging is associated with impairment of certain mental functions, according to the National Institute on Aging. The brain undergoes changes including functional decline in neurons important to learning, memory, planning, and other complex mental activities, as well as increased oxidative stress. In healthy people, these changes may result in varying degrees of age-related memory decline. Source Naturals can help, with a full line of cognitive support products.
Mental Edge®: Bio-Aligned Formula
MENTAL EDGE is a literal multivitamin for your brain. MENTAL EDGE supports production of neurotransmitters including acetylcholine, antioxidant defense, energy generation, stress response and myelin sheath generation. It features nutrients needed for production of neurotransmitters— chemical messengers in the brain’s communication system. One of the most important of these is acetylcholine, which is necessary for memory and muscle movement. MENTAL EDGE also contains antioxidants—vitamin C, ginkgo, DMAE, and zinc—to protect the neuron cell membranes where electrical signaling takes place. Adaptogenic herbs provide the brain with support and energy to deal with environmental stress. Energy-generating ingredients such as ginkgo and B-vitamins are vital to the high-powered functioning of your brain. Vitamins B-5 and B-12 are also important for formation of myelin, a substance that forms a protective insulating cover around certain nerve fibers and increases nerve impulse conduction.
MegaMind™: Bio-Aligned Formula When memory symptoms* are severe, you may need a formula with extraordinary cognitive support. MEGAMIND addresses many of the same body systems as MENTAL EDGE, but does so with megadoses of brain nutrients, such as L-pyroglutamic acid and vitamin B-1 for neurotransmitter production. It also adds bacopa and the inhibitory neurotransmitter GABA to support neurotransmitter production, and higher potency vitamin B-12 for myelin sheath generation. Like MENTAL EDGE, MEGAMIND supports energy generation and antioxidant defense. MEGAMIND augments basic support for the brain’s immense energy requirements with higher potency vitamin B-1, and with one of nutritional science’s most advanced, high-tech nutrients, alpha-lipoic acid. Lipoic acid is also an antioxidant, as are gotu kola and grape seed. MEGAMIND also supports circulation with ginkgo and gotu kola.
Mega Mind: Bio-Aligned Formula HIGHER MIND is another multi-system support formula, which features Phosphatidyl serine, a structural component of nerve cell membranes, and the botanical vinpocetine. HIGHER MIND nourishes neurotransmitter production, cell membrane stability, energy generation, antioxidant defense and myelin sheath generation.
Neurotransmitter Production: Bacopa, GABA, L-Glutamine, L-Pyroglutamic Acid, Taurine, N-Acetyl L-Tyrosine, Manganese, Vitamins B-1 & B-6
Acetylcholine Production: Acetyl L-Carnitine, DMAE, Gotu Kola, L-Pyroglutamic Acid, Vitamin B-5
Myelin Sheath Generation: Vitamins B-5 & B-12
Energy Metabolism: Acetyl L-Carnitine, Ginkgo Biloba, L-Glutamine, alpha-Lipoic Acid, Calcium, Magnesium, Manganese, Potassium, Zinc, Vitamins B-1, B-2, B-3, B-5, B-6 & B-12, Biotin,Folic Acid
Circulation: Ginkgo Biloba, Gotu Kola
Antioxidant Defense: DMAE, Ginkgo Biloba, Gotu Kola, Grape Seed, alpha-Lipoic Acid, Zinc, Vitamin C
Complementary Cognitive Support Products
For additional support, you can supplement Source Naturals Bio-Aligned formulas with these single ingredient products: ACETYL L-CARNITINE and DMAE are both important to the synthesis of acetylcholine, a key neurotransmitter associated with higher cognitive functions, such as learning and memory. DHA (NEUROMINS®) is an omega-3 fatty acid that plays a significant role in cerebral development, especially during fetal development and infancy. GINKGO is renowned for promoting blood flow to the brain. Source Naturals GINKGO-24™ is a standardized concentration of Ginkgo biloba leaves, yielding 24% ginkgo flavone glycosides and 6% terpenes (the key constituents). Phosphatidyl SERINE is necessary for the health of nerve cell membranes, where electrical signaling takes place. These membranes are critical to information processing. VINCAMINE, an alkaloid obtained from the periwinkle plant, supports cerebral metabolism by promoting blood flow and oxygen and glucose utilization. VINPOCETINE is a derivative of vincamine, shown in research studies to improve cognitive performance and alleviate the short-term memory loss that may accompany stress or aging.
Lifestyle Tips for Cognitive Health: A Strategy for Wellness SM
Eat Well: Recent research suggests that diets rich in beta-carotene and vitamins C and E help reduce memory problems, probably by lessening oxidative stress. And new animal research at the University of Toronto found that a high-fat diet slowed the ability of rats to learn new tasks. Use Your Brain: Learn a foreign language or new hobby, do crossword puzzles, read books, and cut back on TV. Scientists at Case Western found that people who were less mentally active in middle age were three times more likely to experience memory decline as they got older. Stay Active: Vigorous walking can improve mental processes in aging individuals, according to research. Aerobic exercise increases oxygenation and blood flow to the brain, resulting in improved memory, organization, and the ability to juggle intellectual tasks. Manage Stress: Longterm anxiety or depression can make a person more forgetful. Try to regulate stress, increase social contacts, and, if necessary, seek professional help. Get Organized: Make the most of your cognitive abilities, through the use of memory aids such as “to-do” lists, notes, or calendars.
Higher Mind - Smart Nutrients for the Performance of a Lifetime...
June 02, 2005 12:18 PM
Our adult years are the time to reap the fruit of an active, meaningful life – appreciated by family and friends who value our experience and knowledge. For some, however, their later years are clouded by a mental decline that erodes their capacity to enjoy life. More of us are becoming apprehensive about the future health of our minds. Will we still be able to communicate our needs as well as our wisdom? As science focuses its investigative might on the workings of the human brain, new findings suggest that it is possible to enjoy a vital, healthy brain and mind – well into old age. Based on compelling research, Source Naturals formulated HIGHER MIND. It contains the most important Neuroceuticals™ now recognized by nutrition scientists – including Phosphatidyl serine, a natural nutrient that promotes cognitive function. The connection is clear: nourish your brain; enrich your life.
To have a healthy, well-functioning brain and nervous system, we need the correct nutrients. Our diets must provide the necessary raw materials for nerve cells to grow, for the synthesis of neurochemicals, and for the maintenance of nerve cell membranes. Nutritional deficiencies can alter the brain’s metabolism, which is expressed by changes in perception and thinking, behavior and mood.
Brain Cells – Issued at Birth
Before birth, neurons (nerve cells) are created at the amazing rate of 15 million per hour. As infants, we have over 100 billion neurons, but this is the most we will ever have because – unlike most other cells in our body – nerve cells do not reproduce. A different strategy is used to replace the neurons that are naturally lost throughout life: nerve cells repair themselves and grow by extending branches of nerve fibers called dendrites (from the Latin word for tree). These are the communication links with other neurons that form the circuitry of the brain. A single neuron may be in contact with up to a hundred thousand others! When the density of this fragile organic communication network decreases, we experience a corresponding decline in mental acuity.
Brain Cell Membranes
The membrane is the working surface of a cell. It needs to be strong yet flexible, so the cell can maintain its integrity and be able to move and change shape. The membrane regulates the flow of nutrients into the cell and the removal of waste, plus controls the passage of molecular messages from outside the cell to its interior. Membrane ion pumps use a third of the cell’s energy just to maintain the correct ratio of sodium to potassium. In neurons, a rapid exchange of sodium and potassium ions across the nerve membrane is responsible for their unique ability to generate the electrical impulses that are the basis of all communication in the nervous system. As cells age, their membranes become less fluid and more rigid. Key membrane molecules called phospholipids are crucial to the health of neuron membranes, allowing the brain to maintain its youthful quality. The phospholipids in HIGHER MIND – especially Phosphatidyl serine and Phosphatidyl choline – are essential nutritional supplements for the aging brain.
Phosphatidyl Serine – Key to Cognition
For the past decade, researchers have been investigating the role in brain health of a remarkable neuroceutical, Phosphatidyl serine (PS). This key structural molecule is integral to the matrix of fats and proteins that compose cell membranes. Although PS is found in all the cells of the body, its highest concentration is in nerve cell membranes. PS is rarely found in the foods we eat, so the body has to synthesize it, but the process is energy- intensive and becomes less efficient with age. Consequently, our levels of PS tend to decline as we get older. PS taken as a dietary supplement is well-absorbed, readily reaching the brain, where it helps create more effective, well-structured nerve cell membranes. The positive effects of PS supplementation have been demonstrated by 23 clinical studies with over 1200 human subjects, ages 43 to 90. Consistent and statistically significant results have confirmed the value of PS in improving age-related cognitive decline, as well as in improving behavioral aspects such as apathy and withdrawal.1 A major study concluded that for one particular measurable parameter of higher mental functions, PS recipients achieved scores of persons roughly 12 years younger.2 Nerve Growth Factor (NGF) is one of the most important proteins the body makes. It enables neurons to extend dendrites out to other neurons, allowing the brain to maintain an effective communication network. In experiments, PS enhanced the production and reception of NGF, which tend to drop off radically with age.3 The effects of PS at the cellular level are manifest in the performance of the brain as a whole. Subjects taking PS showed increased levels of brain energy metabolism. This enhancement corresponded to higher performances on cognitive tests.4
The Chemistry of Thought
Science now understands the role of neurotransmitters in regulating the body’s complex network of behavior. Neurotransmitters are the chemicals used by neurons to communicate with each other. Activated by a neuron’s electrical impulse, neurotransmitters travel between nerve cells, where they excite or inhibit (in various degrees) the electrical impulse in neighboring cells. One of HIGHER MIND’S key strategies is to improve the brain’s ability to produce and use acetylcholine, a key excitatory neurotransmitter. Acetylcholine is essential for both the storage and recall of memory, and partly responsible for concentration and focus. It also plays a significant role in muscular coordination. Patients showing cognitive decline may exhibit reduced ability to synthesize and utilize acetylcholine.5 The chemical building blocks of acetylcholine and other neurotransmitters are called precursors. The most important one for acetylcholine is DMAE (dimethylaminoethanol). This natural substance is found in various fish, such as anchovies and sardines. Supplements of DMAE (and Phosphatidyl choline) promote increased levels of choline in the brain. Acetylcholine is created when an acetyl group is attached to the choline molecule, with the help of choline acetyl transferase (CAT), a key brain enzyme. Acetyl L-carnitine is an amino acid that activates this enzyme. Acetyl L-carnitine may also help reduce lipofuscin deposits in the brain because of its involvement in the metabolism of fatty acids.6 Lipofuscin is composed of oxidized fats and proteins; the brown “age spots” on the back of an elderly person’s hand are made of lipofuscin. The amino acid L-pyroglutamic acid sensitizes the acetylcholine receptor sites on a neuron membrane. A given amount of acetylcholine will then have a larger, more powerful effect. Studies have shown that supplements of L-pyroglutamic acid seem to enhance the ability to focus, remember, and learn.
Total Nutrition for the Brain
The neurotransmitters dopamine and noradrenalin are critical to motor coordination, motivation, concentration, and alertness. Like acetylcholine, their production tends to decline with age. The precursors and activators of dopamine and noradrenalin included in HIGHER MIND are the amino acids N-Acetyl L-Tyrosine and DL-phenylalanine (DLPA), plus folic acid, vitamins B-3, B-6, and C. DLPA is also a precursor to PEA, a neuroamine that has a stimulating effect on the brain. Glutamine is an amino acid precursor to glutamic acid, a major excitatory neurotransmitter involved in mental activity and learning. Glutamine acts as an alternative fuel source for the brain when blood sugar levels are low. It also helps the brain dispose of waste ammonia, which is a natural result of protein breakdown but is irritating to neurons even at low levels. GABA is a dietary amino acid which is also an inhibitory neurotransmitter. GABA works to calm and balance the mind, enhancing mental focus. Along with taurine, these two relaxing neurotransmitters provide a balancing influence to the other, excitatory neurotransmitters. Taurine is found in brain tissue more than anywhere else in the body. It has antioxidant properties and serves as a nerve cell membrane stabilizer, preventing excessive or erratic electrical activity in the brain.
The Importance of Magnesium
Magnesium must be present in adequate amounts in the synaptic gaps between neurons or the neurons become hyper-reactive: causing noises to sound excessively loud and emotional reactions to be extreme. Magnesium also activates a key enzyme responsible for maintaining cellular sodium- potassium balance, which is absolutely essential to the electrical activity of nerve cells, as well as to the existence of the cell itself. (Cells would burst if the sodium-potassium ratio were wrong.) Magnesium also helps relax cerebral blood vessels and is important to the manufacture of ATP, the chief energy molecule of the brain. A buildup of aluminum has been found in the brains of some elderly. In 1989, the British medical journal Lancet published a study showing that drinking water with aluminum can increase the risk of damage by up to 50%. An abundant natural element, aluminum is now a common feature in our culture. It’s found in tap water, cookware, deodorants, beverage containers, baked goods, and of course as aluminum foil. In the brain, aluminum breaks down the structure of neurons – causing them to starve – by displacing magnesium from tubulin, a glycoprotein responsible for making microtubules. These tiny pipe-like structures within a neuron provide needed rigidity, as well as transport nutrients from the nucleus down the dendrites to the ends of the nerve cell. Magnesium malate is an excellent form of magnesium that ensures neurons receive this vital mineral.
B is for Brain Vitamins
HIGHER MIND also contains a high profile of B vitamins and other key nutrients that are often N A T U R A L S S O U R C E Strategies for Wellness SM ¤ lacking in older individuals. A deficiency in any of the B vitamins can alter nerve function and psychological well-being. Thiamine (B-1), known as the “nerve vitamin,” was first recognized because its deficiency caused beriberi, a degenerative nerve disease. Thiamine is part of the structure of nerve cell membranes and is important to the reparative process that neurons need to offset the stress of continual firing of the electrical impulse. Low amounts of thiamine can cause cell malnutrition in the hypothalamus, the brain’s memory center. 7 NAD and NADH, two coenzyme forms of Niacin (B-3), are the most plentiful coenzymes in the brain. They are essential to hundreds of enzymatic reactions, including ones that produce energy. NADH can stimulate the synthesis of key mood-elevating neurotransmitters. It is also one of the body’s most potent antioxidants. Pantothenic acid (B-5), cyanocobalamin (B-12), and folic acid are required to form the myelin sheath – the insulating covering of nerve fibers. A diet low in pantothenic acid has been shown to make test subjects emotionally upset, irritable, and depressed.7 A lack of B-12 can result in poor concentration and, in severe deficiencies, hallucinations. Pyridoxine (B-6) is precursor to over 60 enzymatic reactions and is involved in the synthesis of several neurotransmitters.
Brain cells almost exclusively burn glucose for their energy (other cells can also burn fat), and typically require 50% of all the glucose in the blood. Two B-like vitamins help in the utilization of glucose: PAK (pyridoxine alpha-ketoglutarate) may potentiate the effects of insulin and improve glucose utilization to the cells;8 Biotin is important for the transformation of glucose into energy in the brain. Lipoic acid and coenzyme Q10 are metabolic energizers that help produce ATP, the primary energy molecule in the body. Since the brain uses 20% of the body’s total energy supply, efficient ATP production is vital. Lipoic acid and CoQ10 are also powerful antioxidants that help regenerate other antioxidants in the body. The blood vessels feeding the brain become less efficient as we pass middle age. Since the brain depends on the bloodstream to deliver nutrients and oxygen and to remove waste, the quality of this blood flow is paramount to proper brain nutrition. Ginkgo biloba leaf extract has been shown in scientific studies to increase blood flow to the brain by helping vessels to dilate. It also promotes the smoothness and healthy integrity of blood vessel linings.
For the Life of Your Mind Without proper nutrition, the brain will deteriorate; therefore strategies are needed to both enhance current brain function and protect it throughout life. Based on the latest scientific findings, Source Naturals HIGHER MIND is formulated with neuroceuticals that support the mental functions that tend to decline with age. They give your brain the nourishment it needs to integrate perception, memory, and learning into a more comprehensive awareness – so you can excel for a lifetime.
Hangover Formula - Fight Hangovers with this formula...
June 02, 2005 11:37 AM
Whether you plan to “tie one on” during a holiday, or just sip a little wine with dinner, you should be aware that you may experience a form of low-level toxicity. When you drink, your body converts alcohol into toxic by-products, especially one called acetaldehyde. These toxins cause free radical damage and other problems, and are to blame for the hangover experience. HANGOVER FORMULA from Source Naturals may help to prevent and relieve some of the causes of hangovers. Its potent combination of antioxidants and Western and Chinese herbs is designed to help neutralize the negative effects of alcohol and replenish the nutrients it destroys.
Fight Free Radicals
Acetaldehyde causes the creation of free radicals, which can disrupt cellular activities throughout your body. This causes damage that accumulates with continued use, and is particularly threatening in its effect on the liver. But research shows that Vitamins C and E, and the amino acid Cysteine, act as an antioxidant force to counter the acetaldehyde-produced free radicals, helping to protect against long-term damage. HANGOVER FORMULA provides substantial amounts of these nutrients, and includes Cysteine both in its free form and as the powerful N-Acetyl Cysteine.
Help Counteract the Energy Drain
Acetaldehyde also poisons the energy-generating processes in our cells, the Krebs and glycolytic cycles. It breaks down the protein fraction of enzymes needed to keep these energy generation cycles going. It also damages enzymes that help carry nutrients through the intestinal walls, and others used by the liver to activate vitamins so they can be used in the body. This destruction of critical enzyme systems causes the intense fatigue and the feeling of literally being poisoned that are associated with hangovers and with too much drink, too fast. HANGOVER FORMULA provides the vitamins and minerals necessary to replace the damaged enzymes and keep the Krebs and glycolytic energy cycles going. The result? You feel better — stronger and healthier — than you might otherwise.
Guard Against Severe Depletion of Critical Vitamins and Minerals
Alcohol impairs absorption of a wide range of essential vitamins and minerals by the intestines. Many of the vitamins at particular risk are BVitamins such as B1, or Thiamine. Alcohol also disrupts the kidneys’ ability to conserve the mineral Magnesium, which is then flushed out in the urine. To help reduce the risk of severe depletion, HANGOVER FORMULA provides two of the principal minerals related to nerve function — Calcium and Magnesium — plus substantial amounts of all the B-Vitamins, with an especially high level of Thiamine.
The Acetylcholine Connection
Another major effect of alcohol in the body is the destruction of acetylcholine, one of the body’s most important neurotransmitters. HANGOVER FORMULA includes Phosphatidyl Choline, Choline Bitartrate, and DMAE (dimethylaminoethanol), which are precursors for acetylcholine. Alcohol also causes the brain’s sensitive cell membranes to get very “puffy” (or “fluidized” in scientific terms). This is followed by a rebound effect, and thecell membranes get too “thin,” which can result in a lack of coordination and focus. The acetylcholine precursors in HANGOVER FORMULA also help restore the normal levels of fluidity to these cell membranes, and assist in clearing and focusing the mind again.
Naturopaths worldwide address hangovers with cleansing herbs that help the body regain its natural balance. HANGOVER FORMULA employs a sophisticated selection of these powerful herbs. Chinese Herbology contributes Pueraria Flowers (Ko Hua), specifically to cleanse; Magnolia Bark (Hou Pu), to relieve food stagnation; and Gastrodiae Root (Tien Ma), to relieve tension and excessive “liver yang.” Western Herbology provides Gravel Root, Slippery Elm, and Peach Leaves to restore fluid balance, plus Fennel Seeds, Cloves, and Mint to enhance assimilation. Other herbs of benefit include Germinated Rice, Crysanthemum Flowers, Marshmallow Root, and most importantly, Feverfew Leaf and Milk Thistle Seeds. Numerous studies in the scientific publication Lancet have demonstrated the amazing efficacy of the Feverfew Leaf. This traditional herbal remedy apparently helps to block the effects of hormone-like biochemicals called leukotrienes, which — when out of control — cause intense discomfort, until the body can once again get in balance. Three tablets of HANGOVER FORMULA provides 100 mg of a very potent Feverfew Extract. Silymarin, an extract of Milk Thistle Seeds, is the most popular herb in Germany for the liver. It helps keep this major cleansing organ in optimal working order by fighting free radicals and thus minimizing damage. In addition, Silymarin enhances the unique self-regenerative properties of the liver by helping accelerate repair when damage has been done.
Complete Nutritional & Herbal Support
To counter nutrient depletion and ease discomfort during hangover miseries, HANGOVER FORMULA is here to help.
Attentive Child - Enhances Mental Concentration ...
May 31, 2005 05:14 PM
Most children are creative, energetic and spontaneous, but sometimes they don’t focus on requested activities. Sometimes kids find it difficult to apply themselves to the task at hand. Your child’s brain also may work differently than most people’s brains— just like the 5% of the population that is left-handed. Most people think an ultra-active child means an active brain, but active children may actually need a boost in brain metabolism. Source Naturals ATTENTIVE CHILD is a Bio-Aligned Formula™ designed to address the multiple systems that affect children’s ability to focus: neurotransmitters and brain metabolism, nerve cell communication, antioxidant defense, and essential fatty acid metabolism.
Comprehensive Brain Support
Parents are looking for a safe and natural product to support their children’s ability to focus. Source Naturals studied the research and created an experiential formula, based on the latest breakthroughs in cerebral and nervous system biochemistry. Each ingredient in ATTENTIVE CHILD plays a role in brain and nervous system structure or functioning, or is involved in important biochemical pathways. DMAE, a substance normally found in the brain, boosts brain metabolism and has been shown to enhance concentration. L-Aspartate is an amino acid neurotransmitter that stimulates brain activity. Research has shown that some ultra-active children may have special dietary needs for magnesium, zinc and DHA (docosahexaenoic acid). Magnesium is necessary for the transmission of nerve signals, and, along with zinc, for the processing of essential fatty acids into other vital biochemicals. DHA is an essential fatty acid that is very important for cerebral development and effective communication between nerve cells in the brain. Lecithin contains four phospholipids—fatty acid building-block molecules in nerve cell membranes. Phosphatidylserine, in particular, is vital in nerve cell communication and the electrical activity of the brain. Grape seed extract is a plant-derived antioxidant that protects the integrity of fatty acids in nerve cell membranes.
ATTENTIVE DHA™ in Tiny Kid Caps™
The ATTENTIVE CHILD formula can be supplemented with additional DHA. ATTENTIVE DHA Kid Caps are available in easy-to-swallow, small oval softgels, each containing 100 mg of DHA. For children who can’t swallow caps, simply pierce the gel and mix the oil with food. Sweeteners with Low Impact on Blood Sugar The delicious sweetand- tart taste in ATTENTIVE CHILD wafers comes from natural flavors, specially manufactured without sugar for Source Naturals. Unless specified, most flavors in other products contain maltodextrin, a sugar with a high glycemic index. The ATTENTIVE CHILD wafer itself is sweetened with crystalline fructose (natural fruit sugar) and xylitol (a naturally occurring sweetening agent found in many fruits and vegetables). These select natural sweeteners have a very low glycemic index—so ATTENTIVE CHILD will taste great to your child, but have little effect on blood sugar levels. We recommend carefully reviewing the labels of other products. They may contain honey, glucose, sucrose, maltodextrin, and maltose—all of which have moderate-tohigh glycemic indexes. In addition, maple sugar, molasses, malt syrup, rice syrup, and beet sugar contain varying amounts of high-glycemic-index sugars, which can set off blood sugar fluctuations that may affect concentration. Beware of children’s nutritional bars designed to enhance focus and concentration. Most have over 20 grams of sugar per bar. In contrast, each serving of ATTENTIVE CHILD contains only two grams of crystalline fructose, which has little effect on blood sugar.
Glycemic Index of Various Sweeteners
The glycemic index is a ranking of foods based on their immediate effect on blood glucose levels. It measures how much your blood glucose increases over a period of two or three hours after intake. The higher the glycemic index (GI), the greater the fluctuations in blood sugar. Sweetener Glycemic Index†
*sweeteners used in ATTENTIVE CHILD ™ †based on rate of 100 for glucose ††for information, see website www.wcommerce.com
Lifestyle Strategies for Your Child
You can help your child concentrate on schoolwork, chores and other challenges. Start with ATTENTIVE CHILD and ATTENTIVE DHA, and then incorporate a healthy lifestyle and nutrition routine.
Have your child’s overall health checked by a welltrained holistic health care professional, such as a naturopathic physician. It is particularly important to examine the functioning of your child’s thyroid gland (the master regulator of the body’s metabolism, which influences mood and energy level), and blood sugar metabolism (the brain depends on a steady supply of glucose to function properly, particularly when you are trying to concentrate).
Nutritional Health: Feeding the Brain
Help your child maintain a steady supply of energy and brain fuel by providing a balanced diet. Small, frequent meals are preferable since they dispense a steady level of glucose to the brain. Include foods high in the amino acid tyrosine, a precursor to neurotransmitters that support an alert state. It is found in protein foods, such as meat, poultry, beans, tofu, lentils and seafood. Also include complex carbohydrates such as whole grains, fruits and vegetables, which are metabolized slowly and yield a steady supply of glucose. The simple sugars found in candy, cookies, sodas and other processed foods can lead to a rapid rise in blood sugar levels, followed by an abrupt decline, and should be discouraged. It is important to include essential fatty acids, especially omega-3 fatty acids, which are abundant in the brain and essential for its development and normal functioning. Supplement with ATTENTIVE DHA, and encourage your child to eat cold-water fish, such as salmon. Avoid the hydrogenated fats found in processed foods and margarine, as well as chemicals and food additives. A nutrition program consisting of fresh, unprocessed natural foods is the healthiest choice for everyone.
Some experts believe extended time watching TV and playing video games does not support optimal health or school performance. EEG studies have shown that these activities decrease brain activity rather than activating the brain. Encourage your child to spend time in outdoor physical recreation and in creative, challenging activities.
Supplement with ATTENTIVE CHILD and ATTENTIVE DHA
ATTENTIVE CHILD is available in bottles of 30 & 60 chewable wafers. ATTENTIVE DHA Kid Caps (algal-source Neuromins®) are available in 30- & 60-softgel bottles. References Amen, D. Windows into the....Mind. Fairfield, CA: MindWorks Press, 1997. Foster-Powell, K. & Miller, J.B. 1995, International tables of glycemic index. Am J Clin Nutr. 62:871S-93S. Natah, S.S. et al. 1997. Metabolic response to lactitol and xylitol in healthy men. Am J Clin Nutr. Apr; 65(4):947-50. Schmidt, Michael. Smart Fats. Berkeley: Frog, Ltd., 1997. Sears, William. Boston: Little, Brown & Co., 1998.
PhosChol® PPC - Polyenylphosphatidylcholine for memory and liver function ...
May 26, 2005 09:57 AM
PhosChol ® PPC (30sg,60sg)
One Softgel Contains:
Suggested Use: 1 softgel, 3 times daily, or as directed by your health care professional.
PhosChol ® PPC For imporved Brain and Liver Funtion
Phospholipids are the building blocks for cell membranes--the protective layer and gatekeeper of all cells. A good balance of phosphalipids in the diet provides building blocks for healthy cells, but an imbalance can lead to health concerns for customers.
Now Source Naturals offers PhosChol ® PPC, an all-natural, soy-derived, 100% pure source of PolyenylPhosphatidylcholine (PPC). PPC is a phospholipid found in certain foods and in every cell of your body. It is an integral part of cell membranes, essential for their structual and functional integrity. Studies show that PPC helps to maintain and improve membrane fluidity, supports healthy liver, pancreas, cardiovascular and gastrointestinal health.
Composition and Method of increasing Testonsterone...
May 17, 2005 04:01 PM
Composition and method for increasing testosterone levels
Abstract This invention provides compositions and methods related to the administration of deer antler, one or more nor-testosterone precursors, and one or more testosterone precursors, to increase testosterone levels, treat sexual dysfunction, improve sexual function, improve energy, enhance feelings of well-being and increase muscle mass in males. This invention also provides for inhibitors of the enzymes aromatase and/or 5-alpha reductase, to support testosterone levels and avoid undesirable metabolites.
May reduce DHT:
By using velvet deer antler along with the testosterone and nor-testosterone precursors, the antler promotes youth film testosterone levels while balancing and ameliorating dangerous spikes in these levels. Another embodiment of the invention includes herbs that inhibits 5-alpha-reductase reducing undesirable levels of dihyrotestosterone. Another embodiment includes chrysin, which inhibits aromatase and the production of estrogenic steroids.
Deer antler (called Rokujo in Ancient Chinese Medicine) is used for its sexual-reinforcing and anti-aging actions. Wang et al., 36(7) CHEM. PHARM. BULL. 2587-92 (1988). Velvet antler is living tissue that grows at a rate of up to 2 cm/day in some species. Cartilage, bone and support tissues such as nerves, blood vessels and hair follicles of the antler also evidence accelerated growth. Antler is the only mammalian organ that regenerates. These features, responsible for the accelerate growth of velvet antler are likely to be caused by either unique regulatory substances or substances found in other tissues but at lower levels. It is believed that factors actually responsible for the rapid regeneration of the velvet antler can explain the powerful health benefits of the product. Specifically, velvet deer antler regulates the adrenal cortex and energy metabolism, promotes sexual function and growth, and strengthens resistance. Its functions fall into the major categories of general body strengthening, healing, promoting blood cell growth and improving immune and cardiovascular function.
Some of velvet deer antler's key ingredients include lysoPhosphatidyl choline, with hypotensive activity, Phosphatidyl ethanolamines, sphingomyelin, Phosphatidyl choline hypothanthene and uridene, with monoamine oxidase (MAO)-inhibiting and anti-aging effects; polyamines spermine, spermidine and putrescine, with RNA polymerase stimulating effects; gangliosides that may promote memory and learning; and anti-inflammatory amino acids. A wide variety of growth factors are also found in velvet, and may be associated with its growth-promoting activity. Tsujibo et al., 35(2) CHEM. PHARM. BULL. 654-59 (1987).
As taught by ancient Chinese medicine, deer antler tonifies the yang, primarily deficient yang of the kidneys, spleen and heart. Because kidneys are the seat of the basal yang, the most important use of this class of herbs is to tonify the kidney yang, whose principal manifestation of deficiency is systemic exhaustion. Yang deficiency causes impotence, spermatorrhea, watery vaginal discharge, infertility, enuresis, polyuria, wheezing and daybreak diarrhea. Patients with deficient kidney yang very often have decreased plasma thyroid hormone binding proteins, 24-hour urinary 17-ketosteroids, and decreased rate of glycolysis. When treated with tonifiers such as deer antler, these measurements return to normal ranges. BENSKY ET AL., CHINESE HERBAL MEDICINE, MATERIA MEDICA, REVISED EDITION Eastland Press, Seattle, Wash. (1993).
Deer Antler Velvet Full Spectrum Planetary Formulas 30Ct
Deer Antler Velvet Full Spectrum 60ct
Phosphatidylserine––A Nutrient for Mental Fitness...
May 11, 2005 10:26 AM
Phosphatidylserine––A Nutrient for Mental Fitness, an Anti-aging Nutrient for the Brainby Richard Conant, L.Ac., C.N.
As baby boomers age and the senior population swells, more and more people are faced with the impact of aging on the brain. Loss of memory and thinking ability ranks high among aging's most debilitating consequences. Gradual memory loss in people over fifty, when not caused by a specific neurological disease or other medical problem, is defined as "age associated mental impairment" or "AAMI."1
Source Naturals® Phosphatidyl Serine Retains High Potency
May 09, 2005 09:54 AM
Source Naturals® Phosphatidyl Serine Retains High Potency
Formulation Guarantees Most Shelf Stable Product in Soft Gels
Scotts Valley, California - November 5, 2003 - Source Naturals, creators of the highly acclaimed line of health and wellness supplements, is touting its improved form of Phosphatidyl Serine (PS) soft gels as the most shelf-stable PS available. The activity of PS was investigated by the makers of Leci-PS®, and two critical aspects were identified which influence the concentration of PS in soft gels. First, an enzyme used in the manufacture of PS must be eliminated prior to encapsulation, because this enzyme reacts with glycerol (in the gelatin), causing a degradation of PS. Second, it was found that moisture from the gelatin shell must be blocked from migrating into the capsule fill, because the presence of water in the PS fluid will cause a further loss of content.
The new, patent-pending Leci-PS® 20V blend, introduced in Source Naturals Phosphatidyl Serine Complex soft gels, contains an advanced PS formulation, 100% free of residual enzyme activity, which continually inhibits moisture migration. While nearly all other PS soft gels lose potency while sitting on the shelf, Source Naturals' new Leci-PS® soft gels remain stable.
PS is best known for its ability to reverse the effects of age-related cognitive decline and loss of memory, as well as playing a vital role in other brain functions. Phosphatidyl serine has also been shown to reduce stress and depression. PS is found naturally in soy beans, green leafy vegetables, rice and certain meat products. However, consuming an effective amount of PS simply through food is difficult, because the typical American diet includes many refined and processed foods, resulting in a loss of PS content.
"The natural PS content in soybeans is quite low. Approximately 3 kg of soybeans would have to be consumed to attain 100 mg of PS," said Stephen Sturm, Senior Project Manager in Product Development at Source Naturals. "We recommend supplementing the diet with 100 to 300 mg of our pure PS per day. This supplementation is especially beneficial for vegetarians, people on low-fat or low-cholesterol diets, and the elderly."
Source Naturals' PS is derived strictly from plant sources, and manufactured by the company that pioneered the use of plant-based PS. Numerous animal studies and human clinical trials have proven that soy-derived PS is just as efficacious as bovine-derived PS for mental decline. A clinical trial by Crook (1998) showed that three months of supplementation has effects on memory and cognition that are comparable to those of bovine-derived PS, with results even slightly favoring the soy-derived Leci-PS®.